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SkinBioTherapeutics
Annual Report 2019

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FY2019 Annual Report · SkinBioTherapeutics
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256244 SkinBio Therapeutics plc R&A Cover and Spine Spread.qxp  25/11/2019  17:46  Page 1

Annual Report and Financial Statements 
For the Year Ended 30 June 2019

SkinBioTherapeutics plc 

Company Registration Number: 09632164

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SkinBioTherapeutics

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SkinBioTherapeutics

15 Silk House, Park Green, Macclesfield, SK11 7QJ 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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Contents

Statutory and Other Information

Chairman’s Statement

Strategic and Financial Review

Directors’ Report

Corporate Governance Report

Independent Auditor’s Report to the  
Members of SkinBioTherapeutics plc

Statement of Comprehensive Income

Statement of Financial Position

Statement of Cash Flows

Statement of Changes in Equity

Notes to the Financial Statements

1 

2 

3 

8 

11 

20 

23 

24 

25 

26 

27 

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SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  1

Statutory and Other Information

Directors

Secretary

Registered office

Auditor

Registrars

Nominated adviser

Broker

Bankers

Public relations

Martin Hunt
Stuart Ashman (appointed 18 April 2019)
Doug Quinn
Dr Cathy Prescott

Non-Executive Chairman 
Chief Executive Officer 
Chief Financial Officer 
Non-Executive Director 

Doug Quinn 

15 Silk House 
Park Green 
Macclesfield 
SK11 7QJ 

Jeffreys Henry LLP 
Finsgate 5-7 Cranwood Street 
London 
EC1V 9EE 

Share Registrars Limited 
The Courtyard 
17 West Street 
Farnham 
GU9 7DR 

Cairn Financial Advisers LLP 
Cheyne House, Crown Court 
62-63 Cheapside 
London 
EC2V 6AX 

Turner Pope Investments (TPI) Limited
6th Floor, Beckett House
36 Old Jewry
London
EC2R 8DD

SP Angel Corporate Finance LLP 
Prince Frederick House 
35-39 Maddox Street 
London 
W1S 2PP 

Barclays Bank PLC 
1 Churchill Place 
London 
E14 5HP 

Instinctif Partners 
65 Gresham Street 
London 
EC2V 7NQ 

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2  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Chairman’s Statement

2019 has been a transitional and exciting year for SkinBioTherapeutics, with the Company moving from a scientific focus – proving the 
SkinBiotix® technology works in humans - to commencing and, post year end, closing its first commercialisation deal. Overall, the Company 
has been building value through achieving its business objectives and, identifying and developing the future plans and opportunities for its 
technology platform.  

The beginning of the year was dominated by the Company’s first human study, looking at skin irritancy, moisturisation and impact on skin 
barrier. The positive results demonstrated SkinBiotix’s safety and efficacy, and provided the data required to progress its cosmetic application.  

Armed with the positive clinical data and as part of the Company’s transition towards commercialisation, the Board took the decision to 
strengthen the management team with the appointment of Stuart Ashman as Chief Executive in April 2019. This has provided additional 
bandwidth for Dr Catherine O’Neil to focus on the scientific development of the Company and she transitioned into the non-Board role of 
Chief Scientific Officer (CSO).  

The other change has been the Non-Executive Director, Stephen O’Hara. On the back of the positive progress made by the Company since 
its admission to AIM in 2017 and his increasing commitments at OptiBiotix Health plc, he stepped down from the Board in July 2019.   

On behalf of the Board, I would like to take the opportunity to thank both Cath and Stephen for their valuable contributions to the Company 
to date and look forward to Cath’s continuing scientific contribution in her role as CSO.  

During the year, the Company also announced it had raised a total of £1.5m in gross proceeds through a placing of shares to funds managed 
by Seneca Partners Limited, an existing shareholder of the Company. Costs have continued to be carefully managed and the Company ended 
the year with a cash balance of £3.1m (2018: £3.2m), which is line with management’s expectations.   

Since year end, SkinBioTherapeutics has signed its first commercial deal with global specialist chemicals manufacturer Croda International 
plc (“Croda”). Details of the deal were announced recently and are included in the operational review section. This deal marks an important 
milestone for the Company and its proprietary technology, SkinBiotix®. The team is driving other commercialisation opportunities for 2020 
and will update shareholders as soon as these are realised.  

The Company has developed a longer term strategy which will encompass both existing and new technology. The detail is included in the 
strategic section below, but in summary, the Board and management team has identified five different channels in which the Company 
intends to develop its focus. Each channel offers the potential for multiple applications or sub-channels. This ties in with the body of science 
related to the microbiome and its impact on human physiology and diseases which continues to expand and is an area of increasing focus. 

The ‘science-led’ approach will continue to underpin the Company’s strategic focus and is a key element of the commercialisation strategy. 
We look forward to another exciting year ahead. 

Martin Hunt 
Chairman 

25 November 2019

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Strategic and Financial Review

Company background and strategy 
SkinBioTherapeutics seeks to harness the microbiome for human health. The best understood members of the microbiome are the bacteria 
that live in the gut and these have led to the rise in ingesting ‘probiotics’ to promote health. However, an increasing area of focus is the 
microbiome of the skin. 

SkinBioTherapeutics’ proprietary technology, SkinBiotix®, is designed to promote skin health by harnessing the beneficial properties of 
probiotic bacteria and the active components derived from them. The approach taken is to use a ‘lysate’ of probiotic bacteria cells as a topical 
agent. The use of a lysate rather than live bacteria circumvents the possible safety considerations associated with applying live bacteria to 
the skin and the potential formulation difficulties of keeping bacteria alive in a cream. 

Following a strategic review by the Board and new management team, upon appointment of Stuart Ashman, the Company has identified 
five channels in which it intends to develop its focus, encompassing both existing and new technology. Each channel offers the potential 
for multiple applications or sub-channels. 

SkinBiotix® 
This is the Company’s core technology and the primary focus has been on completion of a first human study to generate data and agreeing 
terms for its commercialisation. The agreement with Croda currently extends to the applicability of the SkinBiotix® technology for use in 
cosmetic applications in active skincare. Croda, along with their speciality cosmetics division – Sederma, have a portfolio of over 12,000 global 
cosmetic customers and supply into a market of high growth estimated at $100+bn (Source: Euromonitor passport stats 2016). Opportunities 
exist for the Company to explore the use of the technology in other areas, for example oral indications, toothpaste, mouthwash etc. to prevent 
the build-up of bacteria by reinforcing the gum barriers resistance. Work is underway to further explore this area.  

AxisBiotix 
An emerging area of science is focussed on the gut-skin axis and its role in various diseases. One such disease that is considered to be 
influenced by the gut-skin axis is psoriasis. This is a chronic relapsing inflammatory condition of the skin with a prevalence of ~3% in the 
western world with a market value of $3.9bn with a CAGR of 3.8% (Source Reuters 2019). Current treatments include emollients for relatively 
mild disease, through to the biologic therapies in severe disease. For the group in the middle, mild to moderate psoriasis, mainstay therapy 
tends to be steroid based. Steroids cannot be used long term and have side effects. Thus, there is an unmet clinical need for new, safer ways 
of treating patients in the mild to moderate group. Anecdotal evidence from patients, suggests that many of them have turned to oral 
probiotics as an ‘alternative’ therapy and report success in control of their disease. However, the effects of probiotics on psoriasis has been 
investigated  in  only  two  studies  which  did  not  make  the  choice  of  probiotic  organisms  based  on  known  disease  pathways. 
SkinBioTherapeutics is currently in discussions with a specialist manufacturer of probiotic formulations, in order to design a probiotic blend 
based on known psoriasis disease pathways and the modifying properties of specific bacteria species on these pathways. Since these are 
existing approved formulations there will be little in the way of development work and, subject to agreeing the collaboration agreement 
and initiating the programme, the Company anticipates being able to commence a human study in 2020. 

 
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4  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Strategic and Financial Review (continued)

MediBiotix 
This channel is targeted as the use of technology for medical device applications and currently the Company is focussing on the application 
of its existing SkinBiotix technology for the indication eczema.  

The skin of eczema sufferers is commonly infected with Staphylococcus aureus (S. aureus) and there is documented evidence that this 
infection is the most common cause of eczema flares. On this basis, technologies that can reduce S. aureus load on skin have the potential 
to reduce the incidence of flares. The market for eczema is reported as $3.9bn with CAGR of 3.8% (Source Pharmapoint Global Data 2014). 

Initial work in the lab has demonstrated that SkinBiotix® fulfils a ‘physical mode of action’ with regard to S. aureus – it prevents the attachment 
of S. aureus to the skin. The physical mode of action of SkinBiotix® would allow the Company to progress the eczema programme as a medical 
device rather than a pharmaceutical treatment. This regulatory pathway is potentially a faster route to market.  

In recent months the Company has conducted further lab work to demonstrate the physical mode of action and is currently reviewing this 
data with its regulatory adviser before seeking to engage with the regulatory notified body on the matter. Additionally, the Company is in 
discussions with a number of global advanced woundcare companies to further explore the potential for the use of probiotic lysates in the 
treatment of various categories of wounds.  

CleanBiotix 
Healthcare acquired infections (HAI) remains an area of critical concern for healthcare providers. The growing resistance of certain infection 
strains and the lack of new antibiotics is driving the need to discover and develop new methods of controlling bacterial growth, colonisation 
and infection. The market for HAI is reported at $17.1bn  with a CAGR of 6.1% (Source BCC 2015). 

Opportunities exist in this regard due to the ability of the SkinBiotix® technology preventing the adherence of the pathogen Staphylococcus 
aureus. The Company is working with a third party seeking to initiate exploratory discussions in regard to both HAI and Domestic Hygiene.  

PharmaBiotix 
As an extension to medical device and Axis applications, the Company has the potential to pursue medicinal prescription registration routes 
for current and future technologies. This is a time consuming and expensive pathway, but subject to positive clinical outcomes, has the 
potential for significantly higher financial returns. Whilst SkinBioTherapeutics is not currently targeting this channel it is a future potential 
pathway for both the eczema and psoriasis opportunities and a natural progression from both MediBiotix and AxisBiotix. 

Financial review 
Operating expenditure continued to increase during the course of the year, in line with management forecasts. In February 2019, the Company 
raised £1.5m in gross proceeds through a share placing at 16 pence per share. The Company held £3.1m of cash at year-end (2018: £3.2m). 
Research and development expenditure was £708k (2018: £416k) comprising development work with the University of Manchester, ongoing 
manufacture, scale-up and formulation work as well as the costs for the cosmetic human study. All such expenditure was expensed in 
the period. 

Ongoing operating costs were £652k (2018: £526k) covering employment, consultancy, PLC support costs and marketing. Overall the 
Company made a loss before tax of £1,360k (2018: £941k). 

Operational review 

Clinical update 

The human study for the cosmetic application incorporating the SkinBiotix® technology was the primary focus of the Company for 2019, 
the results of which were detailed in the RNS of 8 April 2019. The study, which commenced in September 2018, was primarily undertaken to 
show the effects of SkinBiotix® on the barrier of healthy skin. The secondary endpoint was to demonstrate that the technology is safe and 
well tolerated in a large group of people (129) using it twice a day for an extended period of time (29 days). The SkinBiotix® technology was 
incorporated within a cream formulation for application by the study subjects.  

The study design involved three groups: 

l Group 1 applied the active (cream containing SkinBiotix®) to one leg and nothing to the other 

l Group 2 applied the vehicle (cream containing no SkinBiotix®) to one leg and nothing to the other 

l Group 3 applied the vehicle to one leg and active to the other. 

Measures of the barrier were then performed in all groups at 15 days and 29 days. The primary measures were Corneometry – a measure of how 
hydrated the skin is, and Transepidermal water loss (“TEWL”) – a measure of water loss from the skin. A change to the barrier might be expected 
to be reflected in an increase in skin hydration or a reduction in TEWL. Some additional measurements of skin elasticity were also taken. 

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The data showed: 

1)    None of the 129 volunteers experienced any adverse skin reactions to the active. 

2)    A statistically significant increase in skin hydration at day 15 with the active, which was better than that produced by the vehicle. This 

effect was seen in the group under 50 years old. At day 29 there was no difference in skin hydration between any of the groups. 

3)    A small but statistically significant decrease in TEWL with the active at day 29 in the group over 60 years old. 

4)    In other age groups and, also, in measures of skin elasticity there was no difference between the vehicle and the active. 

The results of this independent study demonstrated that SkinBiotix® is safe, well tolerated and has efficacy in certain age groups and time 
points. The change in skin hydration and water loss are in line with expectations from laboratory studies which have shown that SkinBiotix® 
increases the levels of proteins within the skin that are crucial for a healthy barrier. The increase in skin hydration in the younger group at day 
15 may reflect the ability of younger skin to respond to the SkinBiotix® faster than older skin.  

First commercialisation agreement signed 

Having completed the study and generated positive data, the Company progressed discussions with third parties interested in licencing the 
technology, culminating in an agreement earlier this month with Croda International Plc. With turnover of c.£1.38bn and a market cap of £6.1bn, 
Croda is a FTSE 100 company using Smart Science to Improve Lives™. Croda delivers innovative, sustainable ingredients across a range of industries: 
Personal Care, Life Sciences, Performance Technologies and Industrial Chemicals. A world leader in the field of skincare actives for the cosmetic 
industry, Croda offers a wide range of ingredients for skin and hair care products that are sold to major cosmetic brands across the world. 

Under  the  terms  of  the  agreement,  SkinBioTherapeutics’  proprietary  SkinBiotix®  platform  will  be  paired  with  Croda’s  expertise  in  the 
development and commercialisation of unique, sustainable, cosmetic ingredients, focusing specifically on the growing skincare actives 
market. Sederma, part of Croda International, is a specialist manufacturer of bioactive ingredients for the cosmetic industry, and will be 
responsible for the development and commercialisation of the SkinBiotix® technology.  

Croda will be establishing a separate manufacturing line for the technology and as design and manufacture of the active ingredient is carried 
out there will be concurrent testing in focussed ingredient application areas which will be detailed in further, additional agreements.  

Any licensed products resulting from this agreement will be sold to Croda’s global portfolio of Personal Care customers. SkinBioTherapeutics 
will be paid tiered royalties based on global sales revenues on any licensed products derived from the partnership which will be covered in 
individual ingredient application agreements. Recognising the development activity required by Croda, the Company anticipates revenue 
generation to commence from these additional agreements from 2021.  

Sales and distribution rights are for the cosmetic sector alone, leaving SkinBioTherapeutics to focus on further applications of its technology 
in other sectors. A key component of this agreement is access to a reliable supply of material and Croda will supply SkinBiotix™ for the 
Company to be able to use in sectors outside of those covered by this agreement.  

Key performance indicators 
The Board recognises the importance of KPIs and their appropriateness to the stage of development of the business. The Company is focused 
on the development of its technology programmes all of which are cash consuming. The KPIs are therefore chosen to monitor the progress 
of the individual programmes, the external market environment and the cash requirements of the Company. 

Financial 

The cash position of the Company is monitored on a continual basis with reference to both the ongoing operational costs of the business 
and more particularly the cash requirements to support its scientific development programmes. The Company maintains a low operating 
cost base such that the majority of its funding is deployed on its development programmes. 

Non-financial 

The Company actively monitors the progress of its development programmes. Timelines exist for each programme with key milestones 
detailed and these are regularly reviewed and updated accordingly. 

In addition, the Company monitors the life science market for; competitive products and technologies, licensing deals within the cosmetic 
industry, scientific research related to the microbiome and regulatory and policy matters in the major markets. 

Principal risks and uncertainties 
Ultimate responsibility for the process by which risk in the business is managed rests with the Board. The principal risks and uncertainties 
facing the Company, as well as mitigating actions, are set out below. While the list is not exhaustive, it is derived from the Company’s detailed 
risk register. These risks are reviewed by the Audit Committee at least biannually, which reports its findings to the Board. 

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6  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Strategic and Financial Review (continued)

The Company’s internal risk identification and management process is as follows: 

l The Executive Team prepares and reviews on a periodic basis, by function, the risk register for the Company. The risk register details 
specific risks to the Company, the quantification of those risks in terms of probability and impact, and mitigating actions required to 
manage these risks. 

l The risk register assigns responsibility for each risk and mitigation plan to one or more members of the Executive Team. 

l The risk register is circulated to the Board in advance of each board meeting and specific risk items may be discussed at board meetings 

or otherwise as appropriate. 

l The risk register is reported to the Audit Committee at least biannually. 

Stage of operations 

SkinBioTherapeutics is at an early stage of development, yet to generate revenues and has a limited history to date. The ability of the business 
to generate revenue depends on the successful completion of the technical and commercial development of its SkinBiotix® platform. The 
business will incur losses for the immediate future and has not yet demonstrated an ability to obtain regulatory approval or commercialise 
its SkinBiotix® platform successfully. 

Clinical development risk 

The commercialisation of the Company’s intellectual property and the potential applications of its technology platform requires ongoing pre-
clinical development, formulation, process development and human consumer/clinical studies that exemplify platform claims. There is a risk 
that the business’s SkinBiotix® platform does not perform as expected and it fails to perform in the applications identified by the Company. 

Furthermore, clinical development and human studies can result in unexpected costs. Agreeing study designs, study endpoints and study 
recruitment timelines without unforeseen delays with regulatory agencies is key. Regulatory body guidelines leading to market authorisation 
may be subject to alteration and are divergent in different jurisdictions. 

Product development timelines 

The Company has identified a number of applications for its SkinBiotix® technology platform. Development programme delays, inconclusive 
results, identification of safety issues, manufacture and formulation failures or regulatory challenges may require additional follow-up studies 
that are not currently envisaged with a consequential impact on development timelines and cash resources. 

Dependence of key personnel 

The Company’s operates with a small team and success is highly dependent on the expertise and experience of its board, management and 
employees. Retention and incentivisation of these individuals is critical to the Company. 

Formulation 

Whilst the Company has developed a formulation appropriate for the cosmetic human study further work is required to ensure the formulation 
remains effective for an extended period. There are risks associated with the means and timeline in establishing the long-term stability of 
the formulation. In addition, the Company will need to develop formulations appropriate for its other indications. It may require a number 
of iterations before suitable formulations are able to be produced. 

Human studies 

SkinBioTherapeutics has invested effort and resources in its SkinBiotix® technology platform and the potential applications of the technology. 
Success in human studies in part hinges on this continuing development activity. It is however possible that the results of these studies may 
not be predictive of those obtained in more advanced, later-stage, expensive, time consuming and difficult to design human studies. 

Intellectual property and proprietary technology 

SkinBioTherapeutics is focused on maintaining and expanding its intellectual property portfolio. The portfolio includes patent applications, 
trademarks and know-how. 

Success of the Company will depend in part on its ability to obtain and maintain effective patent rights. These rights need to be sufficiently 
broad to protect SkinBioTherapeutics’ technology in its chosen markets. The application process is expensive and time-consuming and 
SkinBioTherapeutics may not be able to file all its patent applications in all jurisdictions. 

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SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  7

Some of the Company’s patent applications remain pending and have not been given notice of allowance. National patent offices may raise 
objections in relation to the on-going patent applications. These may result in revised applications or prevent patent applications from being granted. 

Competitive risk 

The Directors believe the skin microbiome to be an innovative area of development and scientific focus. As such this area is subject to 
significant and rapid technological and consumer change. It is an area of interest to academic institutions, government agencies and private 
and public companies. Competition from existing companies and new entrants has emerged and maintaining an IP and technology 
advantage over the competition will require a sustained development focus. 

The need for safe and supportive skin health and well-being products is acknowledged by consumers and healthcare providers around the globe. 
Large multinationals have divisions dedicated to the sector and many have established brands or approved products on the market. These brand 
owners have greater financial and human resources which can be deployed to build and maintain a brand position. Many also have dedicated 
R&D units and could therefore choose to develop technologies that compete with the Company’s SkinBiotix® technology platform. 

Regulatory environment 

The Company operates in a regulated environment that varies dependent upon the jurisdiction. These regulations are subject to change at 
short notice and differ according to any proposed product claims, intended use or marketing route. While the Company will take every effort 
to ensure that it and its partners comply with all applicable regulations, there can be no guarantee of this. Failure to comply with applicable 
regulations could result in the Company being unable to successfully commercialise its technology or any products that incorporates it 
and/or result in legal action being taken against the Company which could have a material adverse effect. 

Brexit 

It is unclear how Brexit will impact the regulatory environment with the relocation of the European Medicines Agency (EMA) and whether 
the Company will require separate approvals for future trade in Europe. The Company may incur delays and additional costs depending on 
the outcome of the Brexit negotiations and the transition of regulatory approvals. 

Outlook 
Having successfully completed the human safety study and subsequently executed a commercial ingredient and manufacturing agreement 
with Croda, the Company will focus on its identified five core areas over the course of 2020 as well as seeking further commercialisation 
opportunities.    

The successful completion of the human safety study for the SkinBiotix® technology was an important milestone this year. The quality of the 
scientific data and the readout from the study have proved to be prerequisites to reaching agreement with Croda. The project will commence 
in early 2020 and supporting its progress will be an important ongoing activity for SkinBioTherapeutics.  

Next in development will be the progression of the eczema programme as a medical device, following the preliminary regulatory assessment. 
This will continue to be a significant workstream in 2020 as will the commencement of the psoriasis programme, something the Company 
expects to be able to announce further progress on early in the new year. The Company will also explore additional application areas in fields 
that include woundcare, skincare, healthcare acquired infections (HAI) and surface cleaning.  

Strong progress has been made this year across the business and the Board and management team are optimistic for the outlook in 2020. 

Stuart J. Ashman 
Chief Executive Officer 

25 November 2019

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8  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Directors’ Report

The Directors present their report and the audited financial statements of the Company for the year ended 30 June 2019. 

Principal activity 
The principal activity of the Company is that of research and development into the effects of lysates derived from the human microbiome 
on skin. 

Directors 
The directors who served the Company during the year were: 

Stuart Ashman
Dr Catherine O’Neill 
Doug Quinn 
Martin Hunt 
Dr Cathy Prescott 
Stephen O’Hara 

(Appointed 18 April 2019) 
(Resigned 4 July 2019) 

(Resigned 4 July 2019) 

The Directors of the Company held the following beneficial interests in the share and share options of SkinBioTherapeutics plc at the date 
of this report: 

Dr Catherine O’Neill

Martin Hunt

Stuart Ashman

Doug Quinn

Dr Cathy Prescott

5,256,989

466,667

–

444,444

56,112

Issued share capital

Ordinary shares
of £0.01 each

Percentage 
held

Share options 
Ordinary              Options 
shares of             exercise 
£0.01 each                    price 

3,892,082                   £0.09 

3,892,082                   £0.09 

4.1%

0.4%

–

3,892,083                   £0.18 

0.3%

2,594,721                   £0.09 

0.04%

Martin Hunt’s shareholding is held through Invictus Management Limited, a company controlled by Mr Hunt. Of the 466,667 shares held by Invictus Management Limited 11,112 
are held in trust for Louise Hunt and 11,111 are held in trust for Oliver Hunt. 

Substantial shareholdings 
As at 20 November 2019, the following interests in 3% or more of the issued share capital appear in the register: 

OptiBiotix Health Plc

Seneca Partners Limited

University of Manchester

Dr Catherine O’Neill

Prof Andrew McBain

                                                              Percentage of 
                                                  issued share capital 
                                                                           35.8% 

                                                                           20.9% 

                                                                             6.2% 

                                                                             4.1% 

                                                                             3.3% 

                             
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SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  9

Directors remuneration 
The Directors received the following remuneration during the year: 

Executive                                                                                  Salaries
Dr Catherine O’Neill (resigned 4 July 2019)                      £41,000

         Share based                      Pension                             Total 
Fees               payments          contributions           remuneration 
–                   £24,620                           £795                       £66,415 

Doug Quinn                                                                           £12,079

£75,140                   £16,414                           £142                     £103,775 

Stuart Ashman (appointed 18 April 2019)                        £52,067

–                      £7,758                           £329                       £60,154 

Non-executive 
Martin Hunt                                                                              £6,180

£24,820                   £24,620                                  –                       £55,620 

Dr Cathy Prescott                                                                     £4,200

£16,800                               –                                  –                       £21,000 

Stephen O’Hara (resigned 4 July 2019)                               £4,200

£16,800                               –                                  –                       £21,000 

                                                                                                            £119,726

£133,560                     £73,412                           £1,266                      £327,964 

Financial instruments 

The Company’s exposure to financial risk is set out in note 2n of the financial statements. 

Research and development 
The Strategic and Financial Review on pages 3-7 gives information of the Company’s research and development activities. 

Events after the reporting date 
Refer to note 17 to the financial statements for further details. 

Going concern 
The financial statements have been prepared on the assumption that the Company is a going concern. When assessing the foreseeable 
future, the Directors have considered the budget for the next 12 months from the date of this report and the cash at bank available as at the 
date of approval of this report and are satisfied that the Company should be able to meet its financial obligations. 

After making enquiries, the Directors have a reasonable expectation that the group has adequate resources to continue in operational 
existence for the foreseeable future. Accordingly, they continue to adopt the going concern basis in preparing the annual report and financial 
statements. 

Statement of directors’ responsibilities 
The Directors are responsible for preparing the Strategic Report and Directors’ Report and the financial statements in accordance with 
applicable law and regulations. 

Company law requires the Directors to prepare financial statements for each financial year. Under that law the Directors have elected to 
prepare the financial statements in accordance with International Financial Reporting Standards (IFRSs) as adopted by the European Union. 
Under company law the Directors must not approve the financial statements unless they are satisfied that they give a true and fair view of 
the state of affairs and profit or loss of the Company for that period. In preparing these financial statements, the Directors are required to: 

l select suitable accounting policies and then apply them consistently 

l make judgements and accounting estimates that are reasonable and prudent 

l state whether applicable IFRSs have been followed subject to any material departures disclosed and explained in the financial statements 

l prepare the financial statements on the going concern basis unless it is inappropriate to presume that the Company will continue in 

business 

                                                                                                                      
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10  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Directors’ Report (continued)

The Directors are responsible for keeping adequate accounting records that are sufficient to show and explain the Company’s transactions 
and disclose with reasonable accuracy at any time the financial position of the Company and enable them to ensure that the financial 
statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the Company and hence for taking 
reasonable steps for the prevention and detection of fraud and other irregularities. The Directors confirm that: 

l so far as each director is aware, there is no relevant audit information of which the Company’s auditor is unaware; and 

l the Directors have taken all the steps that they ought to have taken as directors in order to make themselves aware of any relevant audit 

information and to establish that the Company’s auditor is aware of that information 

The Directors are responsible for the maintenance and integrity of the corporate and financial information included on the Company’s 
website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements may differ from legislation 
in other jurisdictions. 

Auditors 
Jeffrey’s Henry LLP has expressed their willingness to continue in office and a resolution to re-appoint them will be proposed at the 
forthcoming Annual General Meeting. 

This report was approved by the Board of Directors on 25 November 2019 and signed on its behalf by: 

Stuart J. Ashman 
Chief Executive Officer 

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Corporate Governance Report 

As Chairman of SkinBioTherapeutics I have overall responsibility for corporate governance and in promoting high standards throughout the 
Company. As well as leading and chairing the Board my responsibilities are to ensure; 

l Committees are properly structured and operate with appropriate terms of reference 

l The performance of individual directors, the Board and its committees are reviewed on a regular basis 

l The Company has a coherent strategy and sets objectives against this 

l There is effective communication between the Company and its shareholders 

All the directors of SkinBioTherapeutics believe strongly in the importance of good corporate governance for the creation of shareholder 
value over the medium to long-term and to engender trust and support amongst the Company’s wider stakeholders. The Board adopted 
the QCA code in September 2018 and considers that it does not depart from any of the principles of the QCA code. 

The QCA code is constructed around ten broad principles and a set of disclosures. The QCA has stated what it considers to be appropriate 
arrangements for growing companies and asks companies to provide an explanation about how they are meeting the principles through 
the prescribed disclosures. The Directors have considered how they apply each principle to the extent the Board judges these to be 
appropriate in the circumstances and below we provide an explanation of the approach taken in relation to each. There were no key 
governance related matters that occurred during the year. 

Martin Hunt, Chairman. 

Principle

Application 

Establish  a  strategy  and  business  model  which 
promotes long-term value for shareholders 

SkinBioTherapeutics seeks to harness the microbiome for human health and 
has a particular focus on skin. The Company’s proprietary technology is targeted 
at a number of health indications and the Company is initially focused on a 
cosmetic  application  as  a  route  to  initial  value  creation.  The  Company’s 
programme  of  research  and  development  is  intended  to  build  long-term 
shareholder  value  through  a  reliance  on  proven,  rigorous  science  and  the 
Company utilises its public listing as a means to source capital to support its 
R&D programme. 

The  Company  has  an  ongoing  research  agreement  with  the  University  of 
Manchester to identify and develop technologies. In doing so the Company 
intends to avoid a reliance on a single technology and ensure that it has an 
ongoing pipeline of technologies, all related to the human microbiome, at 
different stages of development. The Company will seek to licence technologies 
to large corporates once human proof of principle has been established and 
intends to generate licence revenue through this route. It operates as a virtual 
organisation  with  a  small  but  experienced  management  team  and  a  low 
operating cost base.

     
 
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Corporate Governance Report (continued)

Principle

Application 

Seek to understand and meet shareholder needs and 
expectations 

Take  into  account  wider  stakeholder  and  social 
responsibilities and their implications for long-term 
success 

The Board is committed to communicating openly with shareholders to ensure 
that  its  strategy  and  performance  are  clearly  understood.  Between  the 
Chairman  and  the  executive  directors  an  open  and  regular  dialogue  is 
maintained with the Company’s major shareholders which comprise; 

Shareholder                                                                 Holding 20 November 2019) 

OptiBiotix Health Plc                                                                                      35.8% 

Seneca Partners Limited                                                                                20.9% 

University of Manchester                                                                                 6.2% 

Prof Cath O’Neill                                                                                                4.1% 

Prof Andrew McBain                                                                                         3.3% 

Both  the  University  of  Manchester  and  Andrew  McBain  sold  shares  in  the 
Company in the period June 2018 – August 2018. The sales of these shares were 
actioned in conjunction with the Company’s brokers to maintain an orderly 
market. OptiBiotix Health Plc sold 1.7m shares in August 2019. 

More generally the Board communicates with shareholders through the Annual 
Report and the Interim Statement, trading and other announcement made 
on  RNS  and  at  the  Annual  General  Meeting  where  the  Board  encourages 
to  participate.  The  Company  also  maintains  a  website, 
investors 
www.skinbiotherapeutics.com, which contains information on the Company’s 
business  and  corporate  information.  Following  the  announcement  of  the 
Company’s  half  year  and  full  year  results  the  Chief  Executive  &  CFO,  make 
presentations  to  institutional  shareholders,  private  client  brokers  and 
investment  analysts.  Existing  and  prospective  shareholders  are  able  to 
separately contact the Chairman and Chief Executive via email as detailed on 
the  Company’s  website.  Periodic  meetings  are  held  with  existing  and 
prospective institutional and other investors and the Company presents at 
private investment events during the course of the year. The Company’s brokers 
also produce periodic research notes on the Company.

As a small company engaged in the early stages of technology development 
the Company has a limited but important number of stakeholders. Robust 
science  is  at  the  core  of  the  Company’s  strategy  and  the  Company  has  a 
number of key stakeholders, including its employees, involved in the different 
stages  from  research,  through  manufacture,  formulation  and  testing.  The 
Company assesses each of the companies it works with to ensure the requisite 
standards and values are in place. Ultimately the Company’s technology will be 
used by consumers and ensuring the appropriate development, manufacture 
and marketing of products will be key to the long-term success of the Company. 
Throughout the various stages from initial technology identification to eventual 
product sales the Company is engaged in a continual process of feedback and 
improvement  with  its  stakeholders,  including  eventual  end  users.  The 
Company’s  strategy  is  not  to  market  its  own  products  and  therefore  the 
eventual  licencees  will  be  important  stakeholders  in  the  interface  with 
consumers and the longer-term success of the Company. 

     
 
     
 
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Principle

Application 

Embed effective risk management, considering both 
opportunities 
the 
organisation 

throughout 

threats, 

and 

Ultimate responsibility for the process by which risk in the business is managed 
rests  with  the  Board.  The  Company’s  internal  risk  identification  and 
management process is as follows: 

l The  Executive  Team  prepares  and  reviews  on  a  periodic  basis  the  risk 
register  for  the  Company.  The  risk  register  details  specific  risks  to  the 
Company,  the  quantification  of  those  risks  in  terms  of  probability  and 
impact, mitigating actions required to manage these risks and the control 
mechanisms that are in place to monitor the risks. 

l The risk register assigns responsibility for each risk and the mitigation plan 

to one or more members of the Executive Team. 

l The risk register is circulated to the Board in advance of each board meeting 
and specific risk items may be discussed at board meetings or otherwise as 
appropriate. 

l The risk register is reported to the Audit Committee at least biannually. 

Maintain the Board as a well-functioning, balanced 
team led by the chair

The Board’s primary role is to enhance shareholders’ long-term interests by: 

l determining the Company’s overall strategy and direction 

l establishing  and  maintaining  controls,  audit  processes  and  risk 
management policies to ensure they counter identified risks and that the 
Company operates efficiently 

l ensuring effective corporate governance 

l approving budgets and reviewing performance relative to those budgets 

l approving financial statements 

l approving material agreements and non-recurring projects, and 

l approving senior and Board appointments 

Martin  Hunt  and  Dr  Cathy  Prescott,  both  non-executive  directors,  are 
considered to be independent of the management and are free to exercise 
independence of judgement. 

The  Non-Executive  Directors  are  required  to  commit  sufficient  time  as  is 
necessary, approximately two days per month, to fulfil their obligations. Routine 
commitments include preparation for and attendance at board and committee 
meetings. In addition, the Non-Executive Directors engage in ad-hoc dialogues 
with members or the Executive Team, shareholders and other stakeholders 
as required. 

All directors are subject to reappointment by shareholders at the first Annual 
General Meeting following their appointment and thereafter by rotation. 

The table on page 19 details the attendance record of each director at board 
and committee meetings during the course of the year.

     
 
     
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Corporate Governance Report (continued)

Principle

Application 

Ensure  that  between  them  the  Directors  have  the 
necessary  up-to-date  experience, 
skills  and 
capabilities

Stephen O’Hara and Dr Cath O’Neill both resigned from the Board 4 July 2019. 
Dr O’Neill continues to serve the Company through her engagement as Chief 
Scientific Officer. 

As at 4 July 2019 the Board comprised an independent non-executive chairman, 
two executive directors and one independent non-executive director. One 
director is female and three are male. 

Martin Hunt, Independent Non-Executive Chairman 

Appointed as a director & Chairman in October 2016; Chair of the Remuneration 
Committee and member of the Audit and Insider Committees. 

Martin has had a long executive career in the medtech and life science sectors 
including  sales  and  general  management  roles  with  large  corporations  in 
Europe and the US. He was previously CEO of biomaterials company Tissue 
Science Laboratories plc taking it from start-up through an AIM listing and 
eventual sale to Covidien. More recently he has held a number of non-executive 
roles with both private and public companies. Martin is well versed in the early 
and growth stages of companies in the life science sector as well as bringing 
experience of corporate governance and shareholder communications. 

Martin is the Programme Director of the NIHR translational funding programme 
Invention for Innovation (i4i) and a member of the NIHR strategy board. Martin 
is currently Non-Executive Chairman of Videregen Limited. 

Time commitment of at least two days per month. 

Stuart Ashman, CEO 

Appointed as a director in April 2019 and CEO in July 2019. 

Stuart  is  an  experienced  commercial  chief  executive  with  considerable 
experience in the medtech and life science sectors. 

Prior to joining the Company, Stuart served as CEO of Onbone Oy (“Onbone”), 
a  Finnish  private  equity-backed  medical  device  company.  In  this  role,  he 
successfully established a global sales force and distribution network and led 
the growth of a multi-million pound business. 

Prior  to  Onbone,  Stuart  was  President/CEO  of  Andover  Healthcare  Inc.,  a 
US-based  wound  management  manufacturer,  and  before  then,  was 
President/CEO of TI Group, a UK-based medical/engineering company. Stuart 
also  served  as  Senior  VP,  Global  Sales  &  Strategic  Marketing,  BSN  Medical 
(Biersdorf, Smith and Nephew) and was Director of Sales & Marketing at Smith 
& Nephew Plc, in its Woundcare, Casting & Bandaging division. In these roles, 
Stuart gained extensive experience of both direct sales management across 
multiple geographies, and of business to business selling. He has also been 
involved  in  M&A  transactions  and  has  achieved  considerable  commercial 
success in both small and large companies. 

Stuart is a full-time employee of the Company. 

     
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Principle

Application 

Doug Quinn, CFO 

Appointed as a director and CFO in December 2016 and Company Secretary in 
January  2017;  Member  of  the  Audit  Committee  and  Chair  of  the  Insider 
Committee. 

Doug has been involved in early stage companies through a combination of 
investor, executive and non-executive director and CFO roles for over 18 years. 
He  was  CFO  of  Arthro  Kinetics  Limited,  an  early  stage  tissue  engineering 
company and part of the team that floated the Company on AIM in 2006. A 
chartered management accountant, with a number of years of experience in 
the life science sector, he brings financial expertise gained through executive 
roles and corporate finance transactions. 

Doug is a director and part-time CFO with the life science company Videregen 
Limited. 

Time commitment of between 2-3 days per week. 

Dr Catherine Prescott, Independent Non-Executive Director 

Appointed  as  a  director  in  March  2017;  Chair  of  the  Audit  Committee  and 
member of the Remuneration Committee. 

Cathy has over two decades of experience in research and management in the 
biotech, pharmaceutical and venture capital sectors. Cathy is a visiting professor 
at Kings College London, teaching on the MSc programme ‘Cellular Therapies 
from bench to market’. Cathy brings a broad range of scientific and strategic 
sector expertise and experience. 

Cathy is a non-executive director of Videregen Limited and the International 
Medical Education Trust. 

Time commitment of two days per month. 

The Board has not, at this stage in its development, established a Nominations 
Committee. The Board as a whole continues to review its structure in order to 
provide  what  it  considers  to  be  an  appropriate  balance  of  executive  and 
non-executive experience and skills. 

The Board believes that its blend of relevant experience, skills, personal qualities 
and capabilities is sufficient to enable it to successfully execute its strategy. The 
Board is additionally cognisant that with the recent changes to the Board and as 
the Company seeks to commercialise its technology, this may require additions 
to the Executive Team and wider Board. 

Directors attend seminars and other trade events to ensure that their knowledge 
remains current. 

On the formation of the Board the Directors considered the composition of the 
Audit Committee. Doug Quinn is an executive director and CFO but a member 
of the Committee due to his experience in this area. Both independent directors 
have direct access to the auditors with the exclusion of Doug and vice versa and 
he is excused from any discussions where there is a potential conflict of interest. 

From time to time the Board may require third party advice on various matters 
pertaining to its business, for example in relation to the competitive landscape. 
Appropriate relationships to source such advice have been established.

     
 
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Corporate Governance Report (continued)

Principle

Application 

Evaluate  board  performance  based  on  clear  and 
relevant objectives, seeking continuous improvement 

Promote a corporate culture that is based on ethical 
values and behaviours

With the changes to the Board during the latter months of the financial year 
the Board deferred its evaluation process until this current financial year. The 
performance review will be an internal review managed by the Chairman and 
is expected to be repeated on an annual basis. 

It  is  anticipated  that  the  process  will  involve  each  director  completing  a 
questionnaire as to the effectiveness of the Board and a self-assessment of their 
own contributions. These will be returned to the Chairman and will form the 
basis of individual discussions with each of the directors and a subsequent 
discussion with the Board as a whole. 

The Board’s approach to succession planning is based upon identifying the 
medium to long term objectives of the Company and matching these against 
the  competence  of  directors  and  senior  managers.  The  Board  will  seek  to 
identify potential gaps and recruit to fill these allowing a sufficient lead time. 

The Board believes that the promotion of a corporate culture based on sound 
ethical values and behaviours is essential to maximise shareholder value. The 
Board considers this particularly relevant to the Company in light of the partners 
with which it works, for example the University of Manchester, and recognising 
the intended end use of its technology in products to be marketed to and 
purchased by consumers. The Company operates virtually and aside from its 
board has only two full-time employees. The Executive team engenders open 
and  positive  interactions  with  a  key  focus  on;  scientific  rigour,  innovation, 
creative solutions and collective responsibility. As the Company expands its 
human capability it will look to formalise its culture through an agreed set of 
values and standards. 

The Company’s policies set out its zero-tolerance approach towards any form 
of modern slavery, discrimination or unethical behaviour relating to bribery, 
corruption or business conduct. 

Maintain governance structures and processes that 
are fit for purpose and support good decision-making 
by the Board 

Alongside  setting  the  vision  and  strategy  for  the  Company  the  Board  is 
responsible to ensure that the business is managed for the long-term benefit 
of all shareholders whilst having regard for internal and external stakeholders, 
including employees, customers and suppliers. 

The Board defines a series of matters reserved for its decision and has approved 
terms of reference for its Audit, Remuneration and Insiders Committees to 
which  certain  responsibilities  are  delegated.  The  chair  of  each  committee 
reports to the Board on the activities of that committee. 

     
 
     
 
     
 
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Principle

Application 

The Audit Committee is responsible for: 

l reviewing  the  annual  financial  statements  and  interim  reports  prior  to 

approval 

l reviewing and considering reports on internal financial controls, including 

reports from the auditors 

l considering  the  appointment  of  and  reviewing  the  relationship  with  the 
auditors, including reviewing and monitoring of independence and objectivity 

l reviewing the consistency of accounting policies 

l considering any proposed related party transaction 

The Audit Committee can call for information from the Executive Team and 
consults with the external auditors directly when appropriate or when they are 
required to do so. 

The Remuneration Committee reviews and determines on behalf of the Board 
the pay, benefits and other terms of service of the Executive Directors of the 
Company. 
In  addition,  the  Committee  oversees  the  creation  and 
implementation of all employee share plans. 

The Insider Committee is responsible for: 

l monitoring and ensuring compliance with the Company’s MAR dealing 

policy 

l reviewing the classification of employees, directors and key consultants as 

regards clearance requirements 

l reviewing  and  approving  or  rejecting  as  appropriate  all  requests  for 

dealings in shares in the Company 

Matters reserved for the Board are; 

l determining the Company’s overall strategy and direction 

l establishing  and  maintaining  controls,  audit  processes  and  risk 
management policies to ensure they counter identified risks and that the 
Company operates efficiently 

l ensuring effective corporate governance 

l approving budgets and reviewing performance relative to those budgets 

l approving financial statements 

l approving material agreements and non-recurring projects, and 

l approving senior and Board appointments 

The  Chairman  has  overall  responsibility  for  corporate  governance  and  in 
promoting high standards throughout the Company. As well as leading and 
chairing the Board, the Chairman’s responsibilities are to ensure; 

l committees are properly structured and operate with appropriate terms of 

reference 

l the performance of individual directors, the Board and its committees are 

reviewed on a regular basis

     
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18  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Corporate Governance Report (continued)

Principle

Application 

l the Company has a coherent strategy and sets objectives against this 

l there  is  effective  communication  between  the  Company  and  its 

shareholders 

The CEO provides coherent leadership and management of the Company, leads 
the development of objectives, strategies and performance standards as agreed 
by the Board, ensures that the assets of the Company are maintained and 
safeguarded, leads on investor relations activities to ensure communications 
and the Company’s standing with shareholders and financial institutions is 
maintained. 

The Non-Executive Directors contribute independent thinking and judgement 
through the application of their external experience and knowledge, scrutinise 
the  performance  of  management,  provide  constructive  challenge  to  the 
executive  directors  and  ensure  that  the  Company  is  operating  within  the 
governance and risk framework approved by the Board. 

The  Company  Secretary  is  responsible  for  providing  clear  and  timely 
information flow to the Board and its committees and supports the Board on 
matters of corporate governance and risk. This role is currently filled by the 
Company’s CFO. The Board acknowledges the QCA guidelines on this matter 
and consider the joint roles appropriate for the Company’s size. The Company 
Secretary  has  direct  access  to  the  Chairman  on  matters  of  corporate 
governance. 

In addition to the investor relations activities described above the following 
committee reports are provided; 

The Audit Committee, which comprises Dr Cathy Prescott (Chair), Martin Hunt 
and Doug Quinn, met three times during the course of the year. The Committee 
met with the external auditors prior to the approval of the annual accounts. 
Consideration was given to the auditors’ pre and post audit reports and these 
provided opportunities to review the accounting policies, internal controls and 
the financial information contained within both the annual and interim reports. 
The  Committee  engaged  the  external  auditors  for  a  review  of  the  interim 
statement prior to its release. 

The Remuneration Committee comprised Martin Hunt (Chair) and up to 4 July 
2019,  Stephen  O’Hara  and  met  three  times  during  the  course  of  the  year. 
Dr Cathy Prescott will replace Mr O’Hara on the Committee. 

Remuneration packages for the Executive Directors comprise a basic salary and 
performance  related  bonus.  There  is  a  compulsory  government  pension 
contribution  scheme  in  place  for  all  directors  and  employees.  In  addition, 
Executive Directors and senior employees participate in a share option long 
term incentive plan. 

Communicate how the Company is governed and is 
performing  by  maintaining  a  dialogue  with 
shareholders and other relevant stakeholders 

     
 
     
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Principle

Application 

The  structure  of  the  remuneration  packages  was  established  ahead  of  the 
Company’s IPO in April 2017 and agreed as remaining appropriate. In setting 
remuneration,  including  for  the  incoming  CEO,  the  Committee  took  into 
consideration  the  compensation  packages  of  comparable  AIM 
listed 
companies.  Share  options  were  granted  to  Stuart  Ashman  following  his 
appointment as CEO. 

The Insiders Committee, comprised of Doug Quinn (Chair) and Martin Hunt, 
met seven times during the course of the year to review the Company’s insider 
lists and review and approve requests for dealing in shares in the Company. 

For information regarding the voting of shareholders at general meetings of 
the Company please see the Shareholder Information section of the website. 

Director meeting attendance 
                                                      PLC board meetings                                                                      Committee meetings 
                                                                                                                               Audit                                    Remuneration                                Insider 
                                                 Eligible to        Attended      Eligible to        Attended      Eligible to        Attended      Eligible to        Attended 
Director                                       attend                                           attend                                           attend                                          attend                                

Martin Hunt                                        14                      14                        3                         3                        3                        3                        7                         7 

Stephen O’Hara  
(resigned 4 July 2019)                       14                      12                        –                         –                        3                        3                        –                         – 

Dr Catherine O’Neill  
(resigned 4 July 2019)                       14                      14                        –                         –                        –                        –                        –                         – 

Dr Cathy Prescott                              14                      12                        3                         3                        –                        –                        –                         – 

Doug Quinn                                       14                      14                        3                         3                        –                        –                        7                         7 

Stuart Ashman  
(appointed 18 April 2019)                  2                        2                        –                         –                        –                        –                        –                         – 

     
 
 
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20  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Independent Auditors’ Report to the Members of 
SkinBioTherapeutics Plc 

Opinion 
We have audited the financial statements of SkinBioTherapeutics Plc for the year ended 30 June 2019 which comprise the statement of 
comprehensive income, the statement of financial position, the statement of cash flows, the statement of changes in equity and notes to 
the financial statements, including a summary of significant accounting policies. 

The financial reporting framework that has been applied in the preparation of the financial statements is applicable law and International 
Financial Reporting Standards (IFRSs) as adopted by the European Union. 

In our opinion: 

l the financial statements give a true and fair view of the state of the Company’s affairs as at 30 June 2019 and of the Company’s loss for 

the year then ended; 

l the financial statements have been properly prepared in accordance with IFRSs as adopted by the European Union; 

l the financial statements have been prepared in accordance with the requirements of the Companies Act 2006. 

Basis for opinion 
We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under 
those standards are further described in the Auditor’s responsibilities for the audit of the financial statements section of our report. We are 
independent of the Company in accordance with the ethical requirements that are relevant to our audit of the financial statements in the UK, 
including the FRC’s Ethical Standard as applied to SME listed entities, and we have fulfilled our other ethical responsibilities in accordance with 
these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion. 

Conclusions relating to going concern 
We have nothing to report in respect of the following matters in relation to which the ISAs (UK) require us to report to you where: 

l the Directors’ use of the going concern basis of accounting in the preparation of the financial statements is not appropriate; or 

l the Directors have not disclosed in the financial statements any identified material uncertainties that may cast significant doubt about 
the Company’s ability to continue to adopt the going concern basis of accounting for a period of at least twelve months from the date 
when the financial statements are authorised for issue. 

Key audit matters 
Key audit matters are those matters that, in our professional judgment, were of most significance in our audit of the financial statements of 
the current period and include the most significant assessed risks of material misstatement (whether or not due to fraud) we identified, 
including those which had the greatest effect on: the overall audit strategy, the allocation of resources in the audit; and directing the efforts 
of the engagement team. These matters were addressed in the context of our audit of the financial statements as a whole, and in forming 
our opinion thereon, and we do not provide a separate opinion on these matters. This is not a complete list of all risks identified by our audit. 

Key audit matter

Intangible assets 

The Company had capitalised intellectual property costs amounting 
to £287,672 at 01 July 2018. During the year the Company capitalised 
a further £59,198 (2018: £72,260) relating to intellectual property. 
These capitalised costs are not yet being amortised as the product is 
in the development stage. 

The Directors have assessed whether the costs meet the criteria for 
capitalisation and whether there are any indicators of impairment. 

We focused on whether the costs capitalised met the criteria for 
capitalisation.

How our audit addressed the key audit matter 

We considered whether the nature of the costs met the criteria for 
the costs to be capitalised. 

We vouched a sample of the costs capitalised to invoices to confirm 
that they relate to intellectual property. 

We considered whether the Directors’ policy for the treatment of 
such costs was reasonable and assessed whether the costs included 
in the reconciliation were in line with the Directors’ policy. 

 
 
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Our application of materiality 
The scope of our audit was influenced by our application of materiality. We set certain quantitative thresholds for materiality. These, together 
with qualitative considerations, helped us to determine the scope of our audit and the nature, timing and extent of our audit procedures on 
the individual financial statement line items and disclosures and in evaluating the effect of misstatements, both individually and in aggregate 
on the financial statements as a whole. 

Based on our professional judgment, we determined materiality for the financial statements as a whole as follows: 

Overall materiality

How we determined it

Rationale for benchmark applied 

Financial statements 
£57,000 (2018: £70,000). 

Based on an average of 5% of loss before tax and 1.5% of gross assets. 

We  believe  that  loss  before  tax  and  gross  assets  are  the  primary 
measure used by the shareholders in assessing the performance of the 
Company, whilst gross assets values are a representation of the size of 
the Company. They are generally accepted auditing benchmarks. 

We agreed with the Audit Committee that we would report to them misstatements identified during our audit above £2,850 (2018: £3,500) 
as well as misstatements below those amounts that, in our view, warranted reporting for qualitative reasons. 

An overview of the scope of our audit 
As part of designing our audit, we determined materiality and assessed the risks of material misstatement in the financial statements. In 
particular, we looked at where the Directors made subjective judgments, for example in respect of significant accounting estimates that 
involved making assumptions and considering future events that are inherently uncertain. As in all of our audits we also addressed the risk 
of management override of internal controls, including evaluating whether there was evidence of bias by the Directors that represented a 
risk of material misstatement due to fraud. 

How we tailored the audit scope 

We tailored the scope of our audit to ensure that we performed enough work to be able to give an opinion on the financial statements as a 
whole, taking into account the accounting processes and controls, and the industry in which they operate. 

Other information 
The Directors are responsible for the other information. The other information comprises the information included in the annual report, other 
than the financial statements and our auditor’s report thereon. Our opinion on the financial statements does not cover the other information 
and, except to the extent otherwise explicitly stated in our report, we do not express any form of assurance conclusion thereon. 

In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing so, consider whether 
the other information is materially inconsistent with the financial statements or our knowledge obtained in the audit or otherwise appears 
to be materially misstated. If we identify such material inconsistencies or apparent material misstatements, we are required to determine 
whether there is a material misstatement in the financial statements or a material misstatement of the other information. If, based on the 
work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact. 
We have nothing to report in this regard. 

Opinions on other matters prescribed by the Companies Act 2006 
In our opinion, based on the work undertaken in the course of the audit: 

l the information given in the strategic report and the Directors’ report for the financial year for which the financial statements are prepared 

is consistent with the financial statements; and 

l the strategic report and the Directors’ report have been prepared in accordance with applicable legal requirements. 

256244 SkinBio Therapeutics plc R&A pp01-pp022.qxp  25/11/2019  17:49  Page 22

22  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Independent Auditors’ Report to the Members of 
SkinBioTherapeutics Plc (continued) 

Matters on which we are required to report by exception 
In the light of the knowledge and understanding of the Company and its environment obtained in the course of the audit, we have not 
identified material misstatements in the Directors’ report. 

We have nothing to report in respect of the following matters in relation to which the Companies Act 2006 requires us to report to you if, in 
our opinion: 

l adequate accounting records have not been kept by the Company; or 

l the financial statements are not in agreement with the accounting records and returns; or 

l certain disclosures of Directors’ remuneration specified by law are not made; or 

l we have not received all the information and explanations we require for our audit. 

Responsibilities of Directors 
As explained more fully in the Directors’ responsibilities statement set out on page 9, the Directors are responsible for the preparation of the 
financial statements and for being satisfied that they give a true and fair view, and for such internal control as the Directors determine is 
necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error. 

In preparing the financial statements, the Directors are responsible for assessing the Company’s ability to continue as a going concern, 
disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the Directors either intend 
to liquidate the Company or to cease operations, or have no realistic alternative but to do so. 

Auditor’s responsibilities for the audit of the financial statements 
Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, 
whether due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance is a high level of assurance, 
but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material misstatement when it exists. 
Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected 
to influence the economic decisions of users taken on the basis of these financial statements. 

A further description of our responsibilities for the audit of the financial statements is located on the Financial Reporting Council’s website at: 
www.frc.org.uk/auditorsresponsibilities. 

This description forms part of our auditor’s report. 

Use of this report 
This report is made solely to the Company’s members, as a body, in accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our 
audit work has been undertaken so that we might state to the Company’s members those matters we are required to state to them in an 
auditor’s report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other 
than the Company and the Company’s members as a body, for our audit work, for this report, or for the opinions we have formed. 

Sanjay Parmar (Senior Statutory Auditor) 
For and on behalf of 
Jeffreys Henry LLP, Statutory Auditor 
Finsgate 
5-7 Cranwood Street 
London 
EC1V 9EE 
25 November 2019

 
256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 23

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  23

Statement of Comprehensive Income  
For the Year Ended 30 June 2019 

Continuing operations 
Research and development
Operating expenses

Loss from operations
Finance costs

Loss before taxation
Taxation

Loss for the year
Other comprehensive income

Total comprehensive loss for the year

Basic and diluted loss per share (pence)

The notes on pages 27 to 39 form part of these financial statements.

Notes

2019 
£

2018 
£ 

3

5

(708,081)
(652,400)

(1,360,481)
–

(1,360,481)
212,388

(1,148,093)
–

(1,148,093)

(415,902) 
(525,549) 

(941,451) 
– 

(941,451) 
97,033 

(844,418) 
– 

(844,418) 

14

(0.94)

(0.71) 

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 24

24  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Statement of Financial Position  

As at 30 June 2019

ASSETS 
Non-current assets 
Property, plant and equipment
Intangible assets

Total non-current assets

Current assets
Other receivables
Corporation tax receivable
Cash and cash equivalents

Total current assets

Total assets

EQUITY AND LIABILITIES
Equity
Capital and reserves
Called up share capital
Share premium
Other reserves
Accumulated deficit

Total equity

Liabilities
Current liabilities
Trade and other payables

Total current liabilities

Total liabilities

Total equity and liabilities

Notes

2019
£

2018 
£ 

6
7

8
5, 8

11
11
13
13

9

6,800
346,870

353,670

242,580
210,351
3,124,864

– 
287,672 

287,672 

93,421 
86,272 
3,182,898 

3,577,795

3,362,591 

3,931,465

3,650,263 

1,280,835
4,923,890
247,672
(2,642,266)

1,187,085 
3,577,640 
170,418 
(1,494,173) 

3,810,131

3,440,970 

121,334

121,334

121,334

209,293 

209,293 

209,293 

3,931,465

3,650,263 

These financial statements were approved and authorised for issue by the Board of Directors on 25 November 2019 and were signed on its 
behalf by: 

Doug Quinn 
Director 

Company Registration No. 09632164 

The notes on pages 27 to 39 form part of these financial statements.

 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 25

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  25

Statement of Cash Flows 
For the Year Ended 30 June 2019 

Cash flows from operating activities 
Loss before tax for the period
Depreciation of property, plant and equipment
Share option expenses

Changes in working capital 
(lncrease)/decrease in trade and other receivables
lncrease/(decrease) in trade and other payables

Cash generated by/(used in) operations

Taxation received

Net cash used in operating activities

Cash flows from investing activities 
Payments for property, plant and equipment
Payments for intangible assets

Net cash used in investing activities

Cash flows from financing activities 
Net proceeds from issue of shares

Net cash generated by financing activities

Net (decrease) in cash and cash equivalents
Cash and cash equivalents at the beginning of the period

2019
£

2018 
£ 

(1,360,481)
3,400
77,254

(1,279,827)

(146,159)
(90,959)

(237,118)

88,309

(941,451) 
– 
71,859 

(869,592) 

57,768 
90,633 

148,401 

53,446 

(1,428,636)

(667,745) 

(10,200)
(59,198)

(69,398)

1,440,000

1,440,000

(58,034)
3,182,898

– 
(72,260) 

(72,260) 

– 

– 

(740,005) 
3,922,903 

Cash and cash equivalents at the end of the period

3,124,864

3,182,898 

The notes on pages 27 to 39 form part of these financial statements. 

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 26

26  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Statement of Changes in Equity  

For the Year Ended 30 June 2019

As at 1 July 2017
Loss for the period
Share-based payments

As at 30 June 2018
Loss for the period
Issue of shares
Costs of share issue
Share-based payments

As at 30 June 2019

Share 
capital
£

Share 
premium
£

Other 
reserves
£

1,187,085
–
–

1,187,085
–
93,750
–
–

3,577,640
–
–

3,577,640
–
1,406,250
(60,000)
–

98,559
–
71,859

170,418
–
–
–
77,254

Retained 
earnings
£

(649,755)
(844,418)
–

(1,494,173)
(1,148,093)
–
–
–

Total 
£ 

4,213,529 
(844,418) 
71,859 

3,440,970 
(1,148,093) 
1,500,000 
(60,000) 
77,254 

1,280,835

4,923,890

247,672

(2,642,266)

3,810,131 

Share capital is the amount subscribed for shares at nominal value. 

Share premium is the amount subscribed for share capital in excess of nominal value. 

Other reserves arise from the equity element of a convertible loan issued and converted in the period to 30 June 2017, and from share options 
granted on 5 April 2017 and 18 April 2019. 

Retained earnings represents accumulated profit or losses to date. 

The notes on pages 27 to 39 form part of these financial statements.

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 27

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  27

Notes to the Financial Statements  

For the Year Ended 30 June 2019

General information 

1
SkinBioTherapeutics plc is a public limited company incorporated in England under the Companies Act and quoted on the AIM market of 
the London Stock Exchange (AIM: SBTX). The address of its registered office is given on page 1.  

The principal activity of the Company is the development of technology to protect, manage and restore skin utilising proteins found in the 
human microbiota. 

Significant accounting policies and basis of preparation 

2
a) Statement of compliance 
The Financial statements of SkinBioTherapeutics plc have been prepared in accordance with International Financial Reporting Standards 
('IFRS') as adopted by the European Union, IFRS Interpretations Committee (IFRIC) and the Companies Act 2006 applicable to companies 
reporting under IFRS. 

b) Basis of preparation 
The financial statements have been prepared under the historical cost convention modified by the revaluation of certain financial instruments. 
The accounting policies have been applied consistently in all material respects.  

The financial statements have been presented in Pounds Sterling ('Sterling') as this is the currency of the primary economic environment in 
which the Company operates. 

c) Going concern  
These financial statements have been prepared on a going concern basis. In considering the appropriateness of this assumption, the Board 
has considered the Company's projections for the twelve months from the date of approval of this financial information, including cash flow 
forecasts. The Directors believe that the Company has adequate resources to continue in operational existence for the foreseeable future 
and therefore adopt the going concern basis of accounting in preparing these financial statements. 

d) Estimates and judgements 
The preparation of financial statements requires the Board to make judgements, estimates and assumptions that may affect the application 
of accounting policies and reported amounts of assets and liabilities as at each balance sheet date and the reported amounts of revenues 
and expenses during each reporting period. Any estimates and assumptions are based on experience and any other factors that are believed 
to be relevant under the circumstances and which the Board considers to be reasonable. Actual outcomes may differ from these estimates. 
Any revisions to accounting estimates will be recognised in the period in which the estimate is revised if the revision affects only that period. 
If the revision affects both current and future periods, the change will be recognised over those periods.  

Certain accounting policies which have a significant bearing on the reported financial condition and results of the Company require subjective 
or complex judgements. An example of such areas of judgement is the estimation of the lifetime of intangible assets, the capitalisation of 
development costs and share based payments. 

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 28

28  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2019

Significant accounting policies and basis of preparation continued 

2
e) Application of new and revised International Financial Reporting Standards (IFRSs) 
No new standards or interpretations issued by the International Accounting Standards Board ('IASB') or the IFRS Interpretations Committee 
('IFRIC') have led to any material changes in the Company's accounting policies or disclosures during each reporting period. 

New and revised IFRSs in issue but not yet effective 
The Company has not applied the following new and revised IFRSs that have been issued but are not yet effective: 

Reference

IFRS16

Title

Leases

Summary

Principles for the recognition, measurement,
presentation and disclosure of leases 

Application date of 
standard (Periods 
commencing on or after) 

1 January 2019 

IFRS17

Insurance contracts

Principles for the recognition, measurement,
presentation and disclosure of insurance contracts 

1 January 2021 

The adoption of these Standards and Interpretations is not expected to have a material impact on the financial information of the 
Company in the period of initial application when they come into effect. 

Foreign currencies 

f)
Transactions in foreign currencies are translated at the exchange rate ruling at the date of the transaction. Monetary assets and liabilities 
denominated in foreign currencies at the balance sheet date are translated at the exchange rate ruling at that date. Foreign exchange differences 
on translation are recognised in the income statement. Non-monetary assets and liabilities that are measured in terms of historical cost in a 
foreign currency are translated using the exchange rate at the date of the transaction. Non-monetary assets and liabilities denominated in 
foreign currencies that are stated at fair value are translated at foreign exchange rates ruling at the dates the fair value was determined.  

g) Research and development  
Research expenditure is written off to the statement of comprehensive income in the year in which it is incurred. Development expenditure 
is written off in the same way unless the directors are satisfied as to the technical, commercial and financial viability of individual projects. In 
this situation, the expenditure is deferred and amortised over the period during which the Company is expected to benefit. 

h) Property, plant and equipment  
Property, plant and equipment are stated at historical cost less subsequent accumulated depreciation and accumulated impairment losses, if 
any. Historical cost includes expenditure that is directly attributable to the acquisition of the items.  

Subsequent costs are included in the asset’s carrying amount or recognised as a separate asset, as appropriate, only when it is probable that 
future economic benefits associated with the item will flow to the Company and the cost of the item can be measured reliably. All other repairs 
and maintenance are charged to profit or loss during the financial period in which they are incurred.  

Depreciation on property, plant and equipment is calculated using the straight-line method to write off their cost over their estimated useful 
lives at the following annual rates:  

Plant & machinery 50%  

Useful lives and depreciation method are reviewed and adjusted if appropriate, at the end of each reporting period.  

An item of property, plant and equipment is derecognised upon disposal or when no future economic benefits are expected to arise from the 
continued use of the asset. Any gain or loss arising on the disposal or retirement of an item of property, plant and equipment is determined 
as the difference between the sales proceeds and the carrying amount of the relevant asset, and is recognised in profit or loss in the year in 
which the asset is derecognised.  

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 29

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  29

Impairment testing of intangible assets  

Significant accounting policies and basis of preparation continued 

2
i)
At the end of each reporting period, the Company reviews the carrying amounts of its intangible assets to determine whether there is any 
indication that those assets have suffered an impairment loss. If any such indication exists, the recoverable amount of the asset is estimated to 
determine the extent of the impairment loss (if any).  

Intangible assets with indefinite useful lives are tested for impairment at least annually, and whenever there is an indication that the assets 
may be impaired.  

Tax  
j)
Current tax  
The tax currently payable is based on taxable profit for the period. Taxable profit differs from ‘profit before tax’ as reported in the income 
statement because of items of income or expense that are taxable or deductible in other periods and items that are never taxable or deductible. 
The Company’s current tax is calculated using rates that have been enacted during the reporting period.  

Deferred tax  
Deferred tax is provided using the balance sheet liability method, providing for temporary differences between the carrying amounts of assets 
and liabilities for financial reporting purposes and the amounts used for tax purposes. The amount of deferred tax provided is based on the 
expected manner of realisation or settlement of the carrying amount of assets and liabilities, using tax rates enacted or substantively enacted 
at the balance sheet date.  

A deferred tax asset is recognised only if it can be regarded as more likely than not that there will be suitable taxable profits from which the 
future reversal of the underlying temporary differences can be deducted. 

k) Payroll expense and related contributions  
Wages, salaries, payroll tax, paid annual leave and sick leave, bonuses, and non-monetary benefits are accrued in the period in which the 
associated services are rendered.  

Share-based compensation  

l)
The Company issues share based payments to certain directors and others providing similar services.  

The fair value of the employee and suppliers services received in exchange for the grant of the options is recognised as an expense. The total 
amount to be expensed over the vesting year is determined by reference to the fair value of the options granted, excluding the impact of any 
non-market vesting conditions (for example, profitability and sales growth targets). Non-market vesting conditions are included in assumptions 
about the number of options that are expected to vest. At each statement of financial position date, the entity revises its estimates of the 
number of options that are expected to vest. It recognises the impact of the revision to original estimates, if any, in the income statement, 
with a corresponding adjustment to equity.  

The proceeds received net of any directly attributable transaction costs are credited to share capital (nominal value) and share premium when 
the options are exercised.  

The fair value of share-based payments recognised in the income statement is measured by use of the Black Scholes model, which takes into 
account conditions attached to the vesting and exercise of the equity instruments. The expected life used in the model is adjusted; based on 
management’s best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations. The share price volatility 
percentage factor used in the calculation is based on management’s best estimate of future share price behaviour and is selected based on 
past experience, future expectations and benchmarked against peer companies in the industry. 

m) Financial instruments  
Financial assets and financial liabilities are recognised on the statement of financial position when an entity becomes a party to the contractual 
provisions of the instruments. Financial assets and financial liabilities are initially measured at fair value. Transaction costs that are directly 
attributable to the acquisition or issue of financial assets and financial liabilities (other than financial assets and financial liabilities at fair value 
through profit or loss) are added to or deducted from the fair value of the financial assets or financial liabilities, as appropriate, on initial 
recognition. Transaction costs directly attributable to the acquisition of financial assets or financial liabilities at fair value through profit or loss 
are recognised immediately in the income statement.

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 30

30  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2019

Significant accounting policies and basis of preparation continued 

2
m) Financial instruments continued 
Financial assets 
The Group’s accounting policies for financial assets are set out below. 

Management determine the classification of its financial assets at initial recognition depending on the purpose for which the financial assets 
were acquired and, where allowed and appropriate, revaluate this designation at every reporting date. 

All financial assets are recognised on a trade date when, and only when, the Group becomes a party to the contractual provisions of an 
instrument. When financial assets are recognised initially, they are measured at fair value plus transaction costs, except for those finance assets 
classified as at fair value through profit or loss (‘FVPL’), which are initially measured at fair value. 

Financial assets are classified into the following specified categories: financial assets at FVPL, ‘amortised cost’ or ‘fair value through other 
comprehensive income’ (‘FVOCI’). The classification depends on the nature and purpose of the financial assets and is determined at the time 
of recognition. 

Financial assets are assessed for indicators of impairment at each balance sheet date. Financial assets are impaired where there is objective 
evidence that, as a result of one or more events that occurred after the initial recognition of the financial asset, the estimated future cash flows 
of the investment have been impacted. 

For certain categories of financial asset, such as trade receivables, assets that are assessed not to be impaired individually, the Group recognises 
lifetime expected credit losses (‘ECL’) when there has been a significant increase in credit risk since initial recognition. However, if the credit 
risk on the financial instrument has not increased significantly since initial recognition, the Group measures the loss allowance for that financial 
instrument at an amount equal to 12-month ECL.  

Lifetime ECL represents the expected credit losses that will result from all possible default events over the expected life of a financial instrument. 
In contrast, 12-month ECL represents the portion of lifetime ECL that is expected to result from default events on a financial instrument that 
are possible within 12 months after the reporting date. 

On derecognition of a financial asset measured at amortised cost, the difference between the asset’s carrying amount and the sum of the 
consideration received and receivable is recognised in profit or loss. 

Cash and cash equivalents 
Cash and cash equivalents comprise cash at bank and on hand, demand deposits with banks and other financial institutions, and short-term, 
highly liquid investments that are readily convertible into known amounts of cash and which are subject to an insignificant risk of changes in 
value, having been within three months of maturity at acquisition. Bank overdrafts that are repayable on demand and form an integral part of 
the Group’s cash management are also included as a component of cash and cash equivalents for the purpose of the consolidated statement 
of cash flows. 

Trade receivables 
Trade receivables are recognised initially at the lower of their original invoiced value and recoverable amount. A provision is made when it is 
likely that the balance will not be recovered in full. If there is objective evidence that the recoverability of the asset is at risk, appropriate 
allowances for any estimated irrecoverably amounts are recognised in the income statement. 

Financial liabilities and equity 
Financial liabilities and equity are recognised on the Group’s statement of financial position when the Group becomes a party to a contractual 
provision of an instrument. Financial liabilities and equity instruments issued by the Group are classified according to the substance of the 
contractual arrangements entered into and the definitions of a financial liability and an equity instrument. An equity instrument is any contract 
that evidences a residual interest in the assets of the Group after deducting all of its liabilities. Equity instruments issued by the Group are 
recognised at the proceeds received, net of transaction costs. 

The Group’s financial liabilities include trade payables and accrued liabilities.

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SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  31

Significant accounting policies and basis of preparation continued 

2
m) Financial instruments continued 
Trade payables 
Trade payables are recognised initially at fair value and subsequently measured at amortised cost using the effective interest method. Terms 
on accounts payable range from 10 to 90 days. 

n) Financial risk management  
Risk management objectives  
Management identify and evaluate financial risks on an on-going basis. The principal risks to which the Company is exposed are market risk 
(including interest rate risk, and cash flow risk), credit risk, and liquidity risk.  

Market risk  
Market risk is defined as the risk that the fair value of future cash flows of a financial instrument will fluctuate because of changes in market 
prices. The Company's market risks arise from open positions in (a) interest-bearing assets and liabilities, and (b) foreign currencies; to the 
extent that these are exposed to general and specific market movements (see details below). 

Interest rate risk 
The Company's interest-bearing assets comprise of only cash and cash equivalents. As the Company's interest-bearing assets do not generate 
significant amounts of interest; changes in market interest rates do not have any significant direct effect on the Company's income. 

Currency risk 
The Company is exposed to movement in foreign currency exchange rates arising from normal trading transactions that are denominated 
in currencies other than the respective functional currencies of the Company. The Company does not have a policy to hedge its exposure 
to foreign currency exchange risk as currently overseas transactions are only a small percentage of total transactions and fluctuations in 
foreign currencies are not expected to significantly affect the Company’s total transactions. In future the Company may consider hedging its 
exposure to foreign currency exchange risk. 

Credit risk 
Credit risk refers to the risk that a counterparty will default on its contractual obligations resulting in financial loss to the Company. Credit risk 
arises from cash balances (including bank deposits, cash and cash equivalents) and credit exposures to trade receivables. The Company's 
maximum exposure to credit risk is represented by the carrying value of cash and cash equivalents and trade receivables. Credit risk is 
managed by monitoring clients and performing credit checks before accepting any customers. 

Liquidity risk  
Liquidity risk is the risk that the Company may encounter difficulty in meeting its obligations associated with financial liabilities that are settled 
by delivering cash or other financial assets.  

The Company seeks to manage its liquidity risk by ensuring that sufficient liquidity is available to meet its foreseeable needs.  

o) Capital management  
The Company manages its capital to ensure that it will be able to continue as a going concern while maximising the return to stakeholders. 
The Company's overall strategy remained unchanged during the period.  

The capital structure of the Company consists of cash and cash equivalents, issued capital, the share premium account, the share-based 
compensation reserve resulting from the grant of equity-settled share options to selected directors and others providing similar services, 
and retained earnings.  

The Company is not subject to any externally imposed capital requirements.  

As part of the Company's management of capital structure, consideration is given to the cost of capital.

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 32

32  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2019

3

Operating loss 

An analysis of the Company’s operating loss has been arrived at after charging/(crediting):  
Other income
Research and development
Directors remuneration (including share-based compensation)
Auditors remuneration
    – audit fees
    – other services
Foreign exchange differences
Other operating costs

Total operating expenses

2019
£

(42)
708,081
294,412

9,500
1,750
1,745
345,035

1,360,481

2018 
£ 

(84) 
415,902 
212,541 

10,995 
1,750 
345 
300,002 

941,451 

The Company has one reportable segment, namely the research and development of the SkinBiotix® technology, all within the United 
Kingdom. 

Employees and Directors 

4
The average monthly number of employees and senior management was: 

Executive directors
Non-executive directors
Employees

Average total persons employed

As at 30 June 2019 the Company had 8 employees (2018 : 6). 

Staff costs in respect of these employees were: 

Wages and salaries
Social security costs
Defined contribution pensions
Share-based payments (see note 12)

Total remuneration

2019
Number

 2018 
Number 

2
3
2

7

2019
£

190,613
15,022
2,286
77,254

285,175

2 
3 
1 

6 

2018 
£ 

85,347 
1,799 
427 
71,859 

159,432 

Some of these staff costs are included within research and development. 

All the directors above can be considered to be key management and have the responsibility for planning, directing and controlling, directly 
or indirectly, the activities of the Company. 

The remuneration of directors and key executives is determined by the remuneration committee having regard to the performance of 
individuals and market trends.

  
256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 33

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  33

Employees and directors continued 

4
The Company operates a defined contribution pension scheme for employees and directors. The assets of the scheme are held separately 
from those of the Company in independently administered funds. The amounts outstanding at 30 June 2019 are £1,359 (2018: £841). 

Directors remuneration:

Dr Catherine O'Neill
Doug Quinn
Stuart Ashman
Dr Cathy Prescott
Martin Hunt
Stephen O'Hara

Total remuneration

The highest paid director received total emoluments of £103,775 during the year. 

Taxation 

5
Income taxes recognised in profit or loss 

Current tax 
Current period – UK corporation tax
R&D tax credit
R&D tax credit - prior year

Tax credit for the year

2019
£

66,415
103,775
60,154
21,000
55,620
21,000

327,964

2019
£

–
210,350
2,038

212,388

The tax charge for each period can be reconciled to the loss per the statement of comprehensive income as follows: 

Loss on ordinary activities before tax
Normal applicable rate of tax
Loss on ordinary activities multiplied by normal rate of tax

Effects of:
Disallowables
Capital allowances
R&D enhanced deductions
R&D tax credit
Losses surrendered
Unused tax losses carried forward

UK tax charge/(credit)

(1,360,481)
19.00%
(258,491)

14,846
(1,938)
(155,793)
(212,388)
275,633
125,743

(212,388)

2018 
£ 

64,763 
85,022 
– 
20,083 
54,703 
20,084 

244,655 

2018 
£ 

– 
86,272 
10,761 

97,033 

(941,451) 
19.00% 
(178,876) 

17,180 
– 
(63,895) 
(97,033) 
113,046 
112,545 

(97,033) 

The Company has an unrecognised deferred tax asset of £297,935 at the period end, which has not been recognised in the financial statements 
due to uncertainty of future profits. The Company has an estimated tax loss of £1,568,077 available to be carried forward against future profits. 

 
 
256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 34

34  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2019

6

Property, plant and equipment 

Cost 
At 1 July 2017
Additions

At 30 June 2018
Additions

At 30 June 2019

Accumulated amortisation 
At 1 July 2017
Charge for the period

At 30 June 2018
Charge for the period

At 30 June 2019

Net book value  
At 1 July 2017

At 30 June 2018

At 30 June 2019

7

Intangible assets 

Cost 
At 1 July 2017
Additions

At 30 June 2018
Additions

At 30 June 2019

Accumulated amortisation 
At 1 July 2017
Charge for the period

At 30 June 2018
Charge for the period

At 30 June 2019

Net book value  
At 1 July 2017
At 30 June 2018

At 30 June 2019

Intellectual property is to be amortised over the expected period that the asset generates income. 

Plant &
Machinery
£

–
–

–
10,200

10,200

–
–

–
3,400

3,400

–

–

Total 
£ 

– 
– 

– 
10,200 

10,200 

– 
– 

– 
3,400 

3,400 

– 

– 

6,800

6,800 

Intellectual
property
£

215,412
72,260

287,672
59,198

Total 
£ 

215,412 
72,260 

287,672 
59,198 

346,870

346,870 

–
–

–
–

–

– 
– 

– 
– 

– 

215,412
287,672

215,412 
287,672 

346,870

346,870 

 
 
256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 35

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  35

8

Trade and other receivables 

Corporation tax
VAT recoverable
Other receivables
Prepayments

2019
£

210,351
72,359
3,149
167,072

452,931

2018 
£ 

86,272 
66,086 
150 
27,185 

179,693 

The fair values of the Company's trade and other receivables are considered to equate to their carrying amounts. The maximum exposure to 
credit risk for trade receivables is represented by their carrying amount. There are no financial assets which are past due but not impaired. No 
financial assets are impaired. 

9

Trade and other payables 

Current 
Trade creditors
Accruals
Other taxes
Other payables

2019
£

59,279
45,217
15,479
1,359

121,334

2018 
£ 

130,534 
72,842 
1,835 
4,082 

209,293 

Trade and other payables principally consist of amounts outstanding for trade purchases and ongoing costs. They are non-interest bearing and 
are normally settled on 30-day terms. The directors consider that the carrying value of trade and other payables approximates to their fair value. 
All trade and other payables are denominated in Sterling. The Company has financial risk management policies in place to ensure that all payables 
are paid within the credit timeframe and no interest has been charged by any suppliers as a result of late payment of invoices during the period. 

The fair value of trade and other payables approximates their current book values. 

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 36

36  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2019

10 Financial instruments   
Maturity analysis 
A summary table with maturity of financial assets and liabilities presented below is used by management to manage liquidity risks. The 
amounts disclosed in the following tables are the contractual undiscounted cash flows. Undiscounted cash flows in respect of balances due 
within 12 months generally equal their carrying amounts in the statement of financial position, as the impact of discounting is not material. 

The maturity analysis of financial instruments at 30 June 2019 is as follows: 

Assets 
Cash and cash equivalents
Trade and other receivables

Liabilities 
Trade and other payables
Borrowings

On demand 
Carrying and less than
3 months
amount
£
£

3 to 12
months
£

1 to 2 years
£

2 to 5 years 
£ 

3,124,864
452,931

3,124,864
452,931

3,577,795

3,577,795

121,334
–

121,334

121,334
–

121,334

–
–

–

–
–

–

–
–

–

–
–

–

– 
– 

– 

– 
– 

– 

The maturity analysis of financial instruments at 30 June 2018 is as follows: 

Assets 
Cash and cash equivalents
Trade and other receivables

Liabilities 
Trade and other payables
Borrowings

On demand 
Carrying and less than
3 months
amount
£
£

3 to 12
months
£

1 to 2 years
£

2 to 5 years 
£ 

3,182,898
179,693

3,182,898
179,693

3,362,591

3,362,591

209,293
–

209,293

209,293
–

209,293

–
–

–

–
–

–

–
–

–

–
–

–

– 
– 

– 

– 
– 

– 

 
 
 
 
256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 37

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  37

11 Share capital 

Issued and fully paid

As at 30 June 2017

As at 30 June 2018

Ordinary shares issued at 16p per share
Costs related to shares issued

As at 30 June 2019

Number

Share capital Share premium 
£ 

£

118,708,494

118,708,494

1,187,085

1,187,085

3,577,640 

3,577,640 

9,375,000
–

93,750
–

1,406,250 
(60,000) 

128,083,494

1,280,835

4,923,890 

On 21st February 2019 the Company issued a further 9,375,000 ordinary shares at 16 pence each by way of a further placing of ordinary 
shares to raise finance. 

Share capital is the amount subscribed for shares at nominal value, issued and fully paid. 

Share premium is the amount subscribed for share capital in excess of nominal value. 

The issued ordinary shares carry one voting right per share and do not carry any rights to fixed income. 

12 Share-based payments  
Share Options  
The Company operates share-based payment arrangements to remunerate directors and others providing similar services in the form of a 
share option scheme. The exercise price of the option is normally equal to the market price of an ordinary share in the Company at the date 
of grant. Each share option converts into one ordinary share of the Company on exercise. No amounts are paid or payable by the recipient 
on receipt of the option. The options carry neither rights to dividends nor voting rights.  

Movements in the number of share options outstanding and their related weighted average exercise prices are as follows: 

Outstanding at 1 July
Granted during the year
Forfeited/cancelled during the year

Outstanding at 30 June

2019

2018 

Weighted
average
exercise
price
£

Number of
options

0.09
0.18
–

0.11

11,027,565
–
–

11,027,565

Weighted 
average 
exercise 
price 
£ 

0.09 
– 
– 

0.09 

Number of
options

11,027,565
3,892,083
–

14,919,648

On 30 June 2018 the exercise date of the 648,680 options in pool 3 was extended to 31 December 2019. The fair value was recalculated 
based on the original valuation with the new exercise date, and then the additional fair value added due to the extension charged to the 
statement of comprehensive income over the extended period.  

On 18 April 2019, 3,892,083 options were granted at an exercise price of £0.18 per share and are exercisable based upon achieving three 
performance conditions, with a third of the options being granted for each condition. The performance conditions are based on the 
achievement of an 40p share price for more than a 30-day continuous period, the achievement of an 80p share price for more than a 30-day 
continuous period, and on the commercial viability of developed products, or the entering into of joint ventures, partnerships, collaborations 
or agreements for the sale or licensing of products.  

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 38

38  |  SkinBioTherapeutics plc  Annual Report & Accounts 2019

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2019

12 Share-based payments continued 
The fair values of the share options issued in the year were derived using the Black Scholes model. The total charge recognised for the year 
ended 30 June 2019 for share options is £77,254 (2018: £71,859). The following assumptions were used in the calculations: 

Deed pool
Grant date 
Exercise price 
Share price at grant date 
Risk-free rate 
Volatility 
Expected life 
Fair value 

Deed pool 
Grant date 
Exercise price 
Share price at grant date 
Risk-free rate 
Volatility 
Expected life 
Fair value 

3b
05/04/17 
9p 
9p 
0.05% 
60% 
2.75 years 
2.30p 

3c 
05/04/17 
9p 
9p 
0.05% 
60% 
2.75 years 
2.30p 

1
05/04/17 
9p 
9p 
0.24% 
60% 
3.5 years 
2.58p 

4 
18/04/19 
18p 
18p 
0.75% 
60% 
3.5 years 
2.85p 

2
05/04/17 
9p 
9p 
0.24% 
60% 
3.5 years 
1.85p 

5 
18/04/19 
18p 
18p 
0.75% 
60% 
3.5 years 
3.99p 

3a
05/04/17 
9p 
9p 
0.05% 
60% 
2.75 years 
2.30p 

6 
18/04/19 
18p 
18p 
0.75% 
60% 
3.5 years 
3.48p 

The closing share price per share at 30 June 2019 was 20.00p (2018: 14.50p) 

Expected volatility is based on a conservative estimate for an AIM listed entity. The expected life used in the model has been adjusted, based 
on management’s best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations. 

13 Reserves 

As at 1 July 2017
Issue of share options
Loss for the period

As at 30 June 2018
Issue of share options
Loss for the period

As at 30 June 2019

Other
reserves
£

98,559
71,859
–

170,418
77,254
–

Retained  
earnings
£

(649,755)
–
(844,418)

(1,494,173)
–
(1,148,093)

Total 
£ 

(551,196) 
71,859 
(844,418) 

(1,323,755) 
77,254 
(1,148,093) 

247,672

(2,642,266)

(2,394,594) 

Other reserves arise from the equity element of a convertible loan that was both issued and converted in the year ended 30 June 2016, and 
share-based payments (see note 12). 

Retained earnings represents accumulated profit or losses to date. 

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 39

SkinBioTherapeutics plc  Annual Report & Accounts 2019  |  39

14 Loss per share 

Basic and diluted loss per share 
Loss after tax (£)
Weighted average number of shares
Basic and diluted loss per share (pence)

 2019
£

2018 
£ 

(1,148,093)
122,047,535
(0.94)

(844,418) 
118,708,494 
(0.71) 

As the Company is reporting a loss from continuing operations for the year then, in accordance with IAS 33, the share options are not 
considered dilutive because the exercise of the share options would have an anti-dilutive effect. The basic and diluted earnings per share as 
presented on the face of the income statement are therefore identical. 

15 Related party transactions 
During the period ended 30 June 2019, the Company was charged fees of £76,940 by Quinn Corporate Services Ltd, a company in which 
Doug Quinn, a director of the Company, is also a director. These fees relate to Doug Quinn’s consultancy services to the Company. As at 
30 June 2019 £26,764 was outstanding.  

During the period ended 30 June 2019, the Company was charged fees of £24,820 and travel expenses of £457 by Invictus Management 
Ltd, a company in which Martin Hunt, a director of the Company, is also a director. These fees relate to Martin Hunt’s consultancy services to 
the Company. As at 30 June 2019 £2,703 was outstanding.  

During the period ended 30 June 2019, the Company was charged fees of £16,800 and travel expenses of £626 by Biolatris Ltd, a company 
in which Dr Cathy Prescott, a director of the Company, is also a director. These fees relate to Dr Cathy Prescott’s consultancy services to the 
Company. As at 30 June 2019 nil was outstanding.  

During the period ended 30 June 2019, the Company was charged fees of £16,800 and travel expenses of £107 by Intelligent Biotech Ltd, a 
company in which Stephen O'Hara, who was a director of the Company at the year end, is also a director. These fees relate to Stephen 
O'Hara’s consultancy services to the Company. As at 30 June 2019 nil was outstanding.  

16  Ultimate controlling party  
No one shareholder has control of the Company. 

17  Events after the reporting date  
The Company has evaluated all events and transactions that occurred after 30 June 2019 up to the date of signing of the financial statements.  

No material subsequent events have occurred that would require adjustment to or disclosure in the financial statements. 

256244 SkinBio Therapeutics plc R&A pp23-imp.qxp  25/11/2019  17:54  Page 40

Perivan    256244

256244 SkinBio Therapeutics plc R&A Cover and Spine Spread.qxp  25/11/2019  17:46  Page 2

Contents

Statutory and Other Information

Chairman’s Statement

Strategic and Financial Review

Directors’ Report

Corporate Governance Report

Independent Auditor’s Report to the  
Members of SkinBioTherapeutics plc

Statement of Comprehensive Income

Statement of Financial Position

Statement of Cash Flows

Statement of Changes in Equity

Notes to the Financial Statements

1 

2 

3 

8 

11 

20 

23 

24 

25 

26 

27 

256244 SkinBio Therapeutics plc R&A Cover and Spine Spread.qxp  25/11/2019  17:46  Page 1

Annual Report and Financial Statements 
For the Year Ended 30 June 2019

SkinBioTherapeutics plc 

Company Registration Number: 09632164

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SkinBioTherapeutics

15 Silk House, Park Green, Macclesfield, SK11 7QJ