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SkinBioTherapeutics
Annual Report 2021

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FY2021 Annual Report · SkinBioTherapeutics
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262369 SkinBio Therapeutics plc Cover Spread (3mm Spine).qxp  29/11/2021  10:37  Page 1

Annual Report and Financial Statements 
For the Year Ended 30 June 2021

SkinBioTherapeutics plc 

Company Registration Number: 09632164

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SkinBio
THERAPEUTICS

15 Silk House, Park Green, Macclesfield, SK11 7QJ

SkinBio
THERAPEUTICS

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
262369 SkinBio Therapeutics plc Cover Spread (3mm Spine).qxp  29/11/2021  10:37  Page 2

Contents

Statutory and Other Information

Chairman’s Statement

Strategic and Financial Review

Directors’ Report

Corporate Governance Report

Independent Auditor’s Report to the  
Members of SkinBioTherapeutics Plc

Consolidated Statement of Comprehensive  
Income

1 

2 

3 

10 

13 

23 

28 

Consolidated Statement of Financial Position

29 

Consolidated Statement of Cash Flows

30 

Consolidated Statement of Changes in Equity

31 

Company Statement of Financial Position

Company Statement of Cash Flows

Company Statement of Changes in Equity

Notes to the Financial Statements

Notice of Annual General Meeting

32 

33 

34 

35 

53 

Notes to the Annual General Meeting Notice

55 

Perivan    262369

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  1

Non-Executive Chairman 
Chief Executive Officer 
Chief Financial Officer 
Non-Executive Director 

Statutory and Other Information

Directors

Martin Hunt
Stuart J. Ashman
Doug Quinn
Dr Cathy Prescott

Secretary

Doug Quinn 

Registered office

15 Silk House 
Park Green 
Macclesfield 
SK11 7QJ 

Auditor

Registrars

Nominated adviser
and broker

Bankers

Public relations

Jeffreys Henry LLP 
Finsgate 5-7 Cranwood Street 
London 
EC1V 9EE 

Share Registrars Limited 
The Courtyard 
17 West Street 
Farnham 
GU9 7DR 

Cenkos Securities plc 
6-8 Tokenhouse Yard 
London 
EC2R 7AS 

Barclays Bank PLC 
1 Churchill Place 
London 
E14 5HP 

Instinctif Partners Limited 
65 Gresham Street 
London 
EC2V 7NQ 

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2  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Chairman’s Statement

At an incredibly challenging time for everyone, 2021 was the year SkinBioTherapeutics demonstrated its resourcefulness 
by successfully executing a consumer study for AxisBiotix, paving the way for its commercial launch. Alongside this the 
Group continued to progress its core SkinBiotix technology through its partners Croda and Sederma. The placing and open 
offer completed in November 2020 provided the working capital to support the AxisBiotix consumer study, initiate new 
programmes of work with the University of Manchester and strengthen the Group’s physical infrastructure. 

In 2019 SkinBioTherapeutics’ strategy identified five channels within which to progress its two core elements of technology – 
SkinBiotix  and  an  emerging  area  of  science  focusing  on  the  relationship  between  the  gut  and  skin.  To  support  this 
multi-channel approach and offer greater corporate flexibility, separate legal entities were established for each channel. 
With the progress made in AxisBiotix during the course of this year, SkinBioTherapeutics is presenting group results for the 
first time. Consolidated financial statements are presented along with Company (SkinBioTherapeutics plc) statements of 
financial position, cash flows and changes in equity. 

AxisBiotix has been the Group’s key focus as it sought to capitalise on the area of research exploring the relationship 
between the gut and skin. In the course of 12 months, from having identified a blend of bacterial strains aligned to the 
disease pathways of psoriasis, the Group designed, initiated and completed a ‘self-managed’ consumer study, reporting 
impressive results with c. 72% of participants who completed the study reporting improvements against the key indications. 
To have made such progress in the course of the financial year is testament to the pragmatic approach and hard work of 
everyone on the team. 

Since year end, the Group has reached the significant milestone of becoming a commercial business, with the launch of 
the AxisBiotix product on 29 October 2021, World Psoriasis Day. 

Development  of  the  Group’s  core  technology,  SkinBiotix,  has  continued  through  Sederma,  the  specialist  ingredient 
manufacturer within Croda Plc. Sederma has progressed the scale-up of lysate manufacture through the various stepped 
increases and is currently preparing to manufacture at the commercial scale of 20,000 litres, in anticipation of sales in 2022. 

In November 2020 the Group completed a placing and open offer raising a total of £4.45m (before expenses). The fundraise 
provided headroom to execute the consumer study for AxisBiotix and prepare for its subsequent commercialisation, as well 
as to provide funds to initiate new scientific development programmes with the University of Manchester and to support 
the transition of the Group from a virtual operation to one with an in-house scientific capability. The Group ended the 
financial year with a cash balance of £4.6m (2020: £2.2m). 

On behalf of the Board, I would like to take the opportunity to thank everyone at SkinBioTherapeutics for the considerable 
progress achieved by the Group over the course of the year. 

Martin Hunt 
Chairman 

29 November 2021 

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  3

Strategic and Financial Review

Company background and strategy 
SkinBioTherapeutics is a life sciences business focused on harnessing the microbiome, the bacteria that live on and in our 
bodies, for human health.  

The Group has two core areas of technology that form five strategic pillars addressing opportunities in cosmetics, food 
supplements, medical devices and longer term, the potential for therapeutics.  

−    SkinBiotix®,  the  Group’s  proprietary  technology,  is  designed  to  promote  skin  health  by  harnessing  the  beneficial 
properties of probiotic bacteria and the active components derived from them. SkinBioTherapeutics’ approach is to use 
a ‘lysate’ of probiotic bacteria cells as a topical agent. The use of a lysate rather than live bacteria circumvents the possible 
safety considerations associated with applying live bacteria to the skin and the potential formulation difficulties of 
keeping bacteria alive in a cream. This form also stabilises the bacteria, making it easier to handle and store.  

−    AxisBiotix™ technology is based on the rapidly emerging area of science that is focused on the gut-skin axis and how 
the constitution of the gut microbiome plays a role in various diseases, such as psoriasis. SkinBioTherapeutics has been 
exploring the relationship between the gut and the skin and the potential to introduce probiotic bacteria into the gut 
and  effect  a  direct  improvement  on  human  skin.  AxisBiotix-Ps™  is  the  first  product  developed  by  the  Group  that 
leverages the gut-skin relationship and is designed to alleviate the symptoms associated with psoriasis. 

Operational review 

SkinBiotix® Pillar (skincare/cosmetics) 

In November 2019, an agreement was signed with Croda Plc, a world leader in the field of active skincare ingredients for 
the cosmetic industry, which sells ingredients for skin and hair care products to major cosmetic brands across the world. 
SkinBioTherapeutics is working directly with Sederma, part of Croda and a specialist manufacturer of bioactive ingredients 
for  the  cosmetic  industry.  Sederma  is  responsible  for  the  development,  manufacturing  and  commercialisation  of  the 
SkinBiotix® technology. 

During the course of the year Sederma updated SkinBioTherapeutics that it had made significant progress against the key 
collaboration milestones. Lysate production had been optimised and analytical sample screening and formulation work 
had been completed. Manufacturing scale-up from 1 litre to 600 litres had been completed successfully and with the formal 
handover of the project from Sederma in Paris to Croda’s manufacturing facility at Ditton, near Widnes, the final scale-up to 
20,000 litres is now being progressed. This is the capacity required to mass produce the SkinBiotix® product at industrial 
levels to market to Sederma’s portfolio of 12,000+ global cosmetic customers.  

Throughout this collaboration, Sederma has identified additional potential scientific and marketing claims for the end 
ingredient. The eventual claims will be an important component of the launch and long-term commercial success of the 
ingredient. To this end, Sederma is continuing its lab work to further substantiate these additional potential claims. This work 
is not impacting the manufacturing scale-up. The Group continues to anticipate 2022 as the period for initial royalty revenues.  

Sales and distribution rights are for the cosmetic sector in “active skincare” alone, leaving SkinBioTherapeutics to focus on 
further applications of its technology in other sectors. A key component of the Croda agreement is to provide access to a 
reliable supply of material to SkinBioTherapeutics, whereby Croda will supply SkinBiotix® for the Company to be able to 
use in other sectors outside of those covered by this agreement.  

AxisBiotix™ Pillar (gut/skin axis) 

In February 2020 SkinBioTherapeutics signed an agreement with Winclove Probiotics B.V. for the development of a probiotic 
blend of ‘good’ bacterial strains based on the modifying properties of specific bacterial species in known psoriasis pathways. 

Psoriasis is a chronic relapsing inflammatory condition of the skin with a prevalence of c.2-3% in the western world. The 
worldwide market for psoriasis treatments was valued at approximately $20bn in 2019 and is expected to grow to $41bn 
in 2027 with a CAGR of 9.2%. Current treatments include moisturising treatments or emollients to soothe and hydrate the 
skin for relatively mild disease, through to biologic therapies in severe cases.  

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4  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Strategic and Financial Review (continued)

For the group with mild-to-moderate psoriasis, the mainstay therapies tend to be steroid-based, which cannot be used long 
term and have side effects. In the management’s opinion, there is a clear unmet clinical need for new, safer ways of treating 
patients with mild to moderate psoriasis. In addition, anecdotal evidence from sufferers suggests that many have turned to 
oral probiotics as an ‘alternative’ therapy as a result of preferring more ‘natural’ treatments and have reported success in 
control of their disease.  

Having successfully formulated a bacterial blend as a probiotic food supplement, branded as AxisBiotix-Ps™, the Group 
intended to initiate a study in a clinical environment. Prevented from doing so by the COVID-19 pandemic, the Group 
redesigned the study as a ‘self-managed’ consumer study that could be managed remotely, without the need for participants 
to attend clinics.  

Of the 265 participants that enrolled onto the study, 177 identified themselves as suffering from mild to moderate psoriasis. 
The participants that self-identified as suffering from psoriasis and completed the study reported the following results: 

l    76% reported that their skin felt less itchy; 

l    75% reported that their skin appeared less red; 

l    73% reported that their skin felt less irritable; and 

l    65% reported that they had fewer ‘flaky patches’ of skin.  

Participants who responded positively about their skin health, also reported positive changes to their lifestyle. On average, 
at day 56: 

l    62% reported having more energy; 

l    64% reported better sleep; and 

l    66% reported positive changes to their general mood. 

In addition, participants in the study who self-identified as suffering from psoriasis and at least one other condition – 80% 
reported a reduction in itchiness and 85% reported their skin felt less irritable. Benefits were also experienced by participants 
who self-identified as having either eczema, acne or rosacea.  

The Group is pursuing a ‘direct to consumer’ commercialisation model for AxisBiotix-Ps™, selling the product through the 
website  AxisBiotix.com. The  psoriatic  community  is  highly  communicative  regarding  the  condition  and  its  treatment, 
therefore, management considers that engagement with sufferers both directly through social media and via the national 
psoriasis associations in the target country markets is an efficient and cost-effective way of penetrating the market.  

Post year end, SkinBioTherapeutics launched AxisBiotix-Ps™ on 29 October 2021 - World Psoriasis Day. AxisBiotix-Ps™ is 
targeted to be sold on a subscription basis with sufferers subscribing on a four or eight-week cycle. The product is sold in 
boxes containing 28 daily sachets and is priced per sachet at £1.50 in the UK and $2.00 in the US and in due course in 
Europe at €1.80 (prices include sales tax and exclude duty and shipping costs). As demonstrated in the consumer study, it 
can take three to four weeks for the benefits of AxisBiotix-Ps to be achieved and consequently new customers receive their 
second month’s supply of the product free. Management therefore expects it to be 3-4 months post launch for an indication 
of customer retention levels and will update the market on initial product sales in March 2022 when the Company releases 
its half year financial results. 

The product has initially been launched in the UK and US with Europe expected to follow in the first half of 2022. There are 
country specific requirements for food supplements in Europe, including labelling instructions and languages. The product 
is manufactured in the Netherlands by Winclove, and finished goods are held at a third party logistics company, also in the 
Netherlands,  from  where  they  are  onward  shipped  directly  to  consumers.  Longer  term  and  subject  to  demand, 
SkinBioTherapeutics will consider bulk shipping finished goods to the US and UK and then onward shipping locally to 
consumers. Outside of these markets, for example, Asia, the Group is considering partnering opportunities for distribution 
and, having begun engagement with potential partners, will look to make progress in this regard in 2022.  

Having initially targeted psoriasis as the first opportunity to leverage the gut-skin axis, the Group is now assessing other 
skin conditions that may benefit from a food supplement. As demonstrated in the consumer study, suffers of eczema, rosacea 
and  acne  benefited  from  taking  AxisBiotix-Ps™.  The  Group  believes  that  a  number  of  the  bacterial  strains  within 
AxisBiotix-Ps™ could form the basis of a core blend to target symptoms of other skin conditions beyond psoriasis.  

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  5

SkinBioTherapeutics is now targeting acne as the next opportunity and anticipates being able to develop a bacterial blend 
and initiate a consumer study during the course of 2022.  

MediBiotix™ Pillar (medtech applications e.g. woundcare) 

The MediBiotix channel is focused on medical device applications incorporating the SkinBiotix® technology. To date, the 
initial target has been eczema and generating a data pack to support the mode of action claims for a medical device 
application. Work is continuing in this regard and in parallel, recognising the progress made with AxisBiotix, management 
is considering developing a food supplement that addresses the symptoms of eczema through the gut-skin axis. 

Management also believes there is significant utility for the technology in the treatment of various classes of skin wounds 
and is in discussion with a number of global advanced woundcare companies in this regard. The Group is targeting a 
commercial agreement to develop and test the SkinBiotix® technology in these advanced indications. 

CleanBiotix™ Pillar (anti-infection) 

The area of healthcare acquired infections (HAI) and bacterial resistance remains an area of critical concern for healthcare 
providers and has been brought into sharp focus through the pandemic. The growing resistance of certain infection strains, 
the lack of new antibiotics, and the rise of the “superbug” is driving the need to discover and develop new methods of 
controlling bacterial growth and infection. 

Staphylococcus aureus (SA) is the most common and one of the most aggressive skin pathogens and is one of the major 
causes of HAI. The Group’s SkinBiotix® technology has been shown to have significant capabilities in preventing SA from 
adhering to and growing on the skin and thus offers a potential route of protection from SA-induced healthcare acquired 
infections. The Group has been in discussions with leading companies in the domestic and commercial hygiene sectors as 
to the utility of the SkinBiotix® technology within these environments.  

This is a challenging area both from a technology and regulatory perspective but equally offers significant opportunities. 
SkinBioTherapeutics will continue discussions targeted at identifying a partner to work with to develop all aspects of this 
market channel. 

Other Research Programmes 

In April  2021  SkinBioTherapeutics  extended  its  collaboration  with  the  University  of  Manchester  for  two  new  research 
programmes. The first programme, which will run for two years, will focus on how the microbiome can influence and 
rebalance the body’s response to inflammation in skin health and skin disease. The aim is for SkinBioTherapeutics to develop 
immune-supporting microbiome formulations to market through everyday products such as skin lotions and creams where 
there is an increasing consumer preference for natural ingredients. 

The second programme addresses oral health and will explore the use of different bacteria, including SkinBioTherapeutics’ 
proprietary lysate SkinBiotix, for oral health and wellbeing. The 12-month programme will develop, and test formulations 
designed to support the health of skin surfaces in the oral cavity targeting disease prevention, oral care and hygiene. These 
formulations could be positioned as standalone products or work alongside traditional oral health and wellbeing products.  

Financial review 
In support of its strategy to develop its technology in a number of channels, SkinBioTherapeutics established separate legal 
entities  for  each  channel.  Activity  commenced  in  AxisBiotix  Limited  during  the  course  of  the  year  and  consequently 
SkinBioTherapeutics 
is  presenting  group  results  for  the  financial  year.  Separately  presented  are  Company 
(SkinBioTherapeutics plc) statements of financial position, cash flows and changes in equity. 

Expenditure  for  the  financial  year  was  lower  than  management’s  expectations  as  a  consequence  of  pivoting  to  a 
self-managed consumer study for AxisBiotix-Ps and reduced activity at the University of Manchester due to COVID-19. 
Research and development expenditure was £506k (2020: £635k) and other operating expenses were £991k (2020: £985k). 
Overall, the Group made a loss before tax of £1,498k (2020: £1,620k).  

In November 2020, SkinBioTherapeutics completed a placing and open offer raising a total of £4.45m gross proceeds. The 
funding enabled the Group to expand its technology pipeline with two additional programmes of work with the University 
of Manchester and secure lab space at the Biosphere complex in Newcastle. Cash used in operating activities was £1,555k 
(2020: £892k) and the Group had a cash balance of £4,610k (2020: £2,159k) at year-end.  

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6  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Strategic and Financial Review (continued)

Key performance indicators 
The Board recognises the importance of KPIs and their appropriateness to the stage of development of the business. The 
Group is focused on the development of its technology programmes all of which are cash consuming. The KPIs are therefore 
chosen to monitor the progress of the individual programmes, the external market environment and the cash requirements 
of the Group. 

Financial 

The cash position of the Group is monitored on a continual basis with reference to both the ongoing operational costs of 
the business and more particularly the cash requirements to support its scientific development programmes. The Group 
maintains a low operating cost base such that the majority of its funding is deployed on its development programmes. 

Non-financial 

The Group actively monitors the progress of its development programmes. Timelines exist for each programme with key 
milestones detailed and these are regularly reviewed and updated accordingly. 

In addition, the Group monitors the life science market for; competitive products and technologies, licensing deals within 
the cosmetic industry, scientific research related to the microbiome and regulatory and policy matters in the major markets. 

Principal risks and uncertainties 
Ultimate responsibility for the process by which risk in the business is managed rests with the Board. The principal risks and 
uncertainties facing the Group, as well as mitigating actions, are set out below. While the list is not exhaustive, it is derived 
from the Group’s detailed risk register. These risks are reviewed by the Audit Committee at least biannually, which reports 
its findings to the Board. 

The Group’s internal risk identification and management process is as follows: 

l    The Executive Team prepares and reviews on a periodic basis, by function, the risk register for the Group. The risk register 
details specific risks to the Group, the quantification of those risks in terms of probability and impact, and mitigating 
actions required to manage these risks. 

l    The risk register assigns responsibility for each risk and mitigation plan to one or more members of the Executive Team. 

l    The risk register is circulated to the Board in advance of each board meeting and specific risk items may be discussed 

at board meetings or otherwise as appropriate. 

l    The risk register is reported to the Audit Committee at least biannually. 

COVID-19 

To date the Group has been able to progress its core development programmes with its partners with no material impact 
caused by COVID-19, including commencing and completing a consumer study for AxisBiotix-Ps. Both Croda and Winclove 
have been able to continue operating throughout the pandemic. Development work at the University of Manchester was 
temporarily suspended because of the closure of the lab facilities, with work recommencing in September 2020. 

Brexit 

Following the United Kingdom’s exit from the EU on 31 January 2020 (“Brexit”) and the end of the transition period the 
Group has experienced additional complexities and administration as it prepares its AxisBiotix-Ps product for commercial 
launch. AxisBiotix-Ps is manufactured in the Netherlands and also shipped from the Netherlands to customers. Brexit has 
placed additional demands on the shipping and importing of the product to customers in the UK. Other than incurring 
additional shipping and administrative costs, there has been no additional impact for the initial launch of the product in 
November 2021. The Group is currently assessing the impact of Brexit on the requirements for it to sell product within 
Europe, including the appointment of a food business operator (FBO). It could potentially make it more difficult for the 
Group to operate its business in the EU as a result of any increase in tariffs and/or more burdensome regulations being 
imposed on UK companies (such as changes in applicable legislation affecting the regulatory pathway of the Group’s 
products,  both  in  Europe  and  in  the  UK).  This  could  restrict  the  Group’s  future  prospects  and  adversely  impact  its 
financial condition. 

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  7

Stage of operations 

SkinBioTherapeutics  is  at  an  early  stage  of  development  and  post  year  end,  entering  into  its  first  phase  of  revenue 
generation. The  extent  to  which  it  can  generate  material  revenue  in  the  near  term  will  be  dependent  on  the  market 
penetration of AxisBiotix-Ps and the successful completion of the technical and commercial development of its SkinBiotix® 
platform. The business will incur losses for the immediate future. 

Clinical development risk 

The commercialisation of the Group’s intellectual property and the potential applications of its technologies requires 
ongoing preclinical development, formulation, process development and human consumer/clinical studies that exemplify 
platform claims. There is a risk that one or more of the business’s technologies does not perform as expected and fails to 
perform in the applications identified by the Group. 

Furthermore, clinical development and human studies can result in unexpected costs. Agreeing study designs, study 
endpoints and study recruitment timelines without unforeseen delays with regulatory agencies is key. Regulatory body 
guidelines leading to market authorisation may be subject to alteration and are divergent in different jurisdictions. 

Product development timelines 

Development programme delays, inconclusive results, identification of safety issues, manufacture and formulation failures 
or regulatory challenges may require additional follow-up studies that are not currently envisaged with a consequential 
impact on development timelines and cash resources. 

Dependence of key personnel 

The Group operates with a small team and success is highly dependent on the expertise and experience of its board, 
management and employees. Retention and incentivisation of these individuals is critical to the Group. 

Formulation 

The Group has developed formulations for its initial indications and will need to repeat this process for other indications. 
There are risks associated with the means and timeline in developing formulations and establishing their long-term stability. 
It may require a number of iterations before suitable formulations are able to be produced. 

Human studies 

SkinBioTherapeutics has invested effort and resources in the development of its technologies. Success in human studies in 
part hinges on this continuing development activity. It is however possible that the results of these studies may not be 
predictive  of  those  obtained  in  more  advanced,  later-stage,  expensive,  time  consuming  and  difficult  to  design 
human studies. 

Intellectual property and proprietary technology 

SkinBioTherapeutics is focused on maintaining and expanding its intellectual property portfolio. The portfolio includes 
patent applications, trademarks and know-how. 

Success of the Group will depend in part on its ability to obtain and maintain effective patent rights. These rights need to 
be sufficiently broad to protect SkinBioTherapeutics’ technology in its chosen markets. The application process is expensive 
and time-consuming and SkinBioTherapeutics may not be able to file all its patent applications in all jurisdictions. 

Some of the Group’s patent applications remain pending and have not been given notice of allowance. National patent 
offices may raise objections in relation to the on-going patent applications. These may result in revised applications or 
prevent patent applications from being granted. 

Competitive risk 

The Directors believe the skin microbiome to be an innovative area of development and scientific focus. As such this area 
is subject to significant and rapid technological and consumer change. It is an area of interest to academic institutions, 
government agencies and private and public companies. Competition from existing companies and new entrants has 
emerged and maintaining an IP and technology advantage over the competition will require a sustained development focus. 

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8  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Strategic and Financial Review (continued)

The need for safe and supportive skin health and well-being products is acknowledged by consumers and healthcare 
providers around the globe. Large multinationals have divisions dedicated to the sector and many have established brands 
or approved products on the market. These brand owners have greater financial and human resources which can be 
deployed to build and maintain a brand position. Many also have dedicated R&D units and could therefore choose to 
develop technologies that compete with those of the Group. 

Regulatory environment 

The  Group  operates  in  a  regulated  environment  that  varies  dependent  upon  the  jurisdiction  and  technology.  These 
regulations are subject to change at short notice and differ according to any proposed product claims, intended use or 
marketing route. While the Group will take every effort to ensure that it and its partners comply with all applicable regulations, 
there can be no guarantee of this. Failure to comply with applicable regulations could result in the Group being unable to 
successfully commercialise its technology or any products that incorporates it and/or result in legal action being taken 
against the Group which could have a material adverse effect. 

S172 Statement 
The Directors acknowledge their duty under s.172 of the Companies Act 2006 and consider that they have, both individually 
and together, acted in the way that, in good faith, would be most likely to promote the success of the Company for the 
benefit of its members as a whole. In doing so, they have had regard (amongst other matters) to: 

l     The likely consequences of any decision in the long term 

The Group’s strategic objectives and the progress made against these during the year, together with the principal risks, are 
detailed in the Strategic and Financial Review on pages 3-9. 

l     The interests of the Group’s employees 

SkinBioTherapeutics is a very small company in terms of its number of employees and recognises these employees are key 
to its business success. Members of the Board maintain frequent contact with employees and the executive team engage 
with employees with regards current performance and future plans and ambitions for the Group. 

l     The need to foster the Group’s business relationships with suppliers, customers and others 

A  consideration  of  the  relationship  with  wider  stakeholders  and  their  impact  on  our  long-term  strategic  objectives  is 
disclosed in Principle 3 of the Corporate Governance Report on pages 13-22. 

l     The impact of the Company’s operations on the community and the environment 

The Group is committed to operating with a high level of corporate social responsibility and environmental sustainability. 
Principle 8 of the Corporate Governance Report provides further disclosure on how we promote a corporate culture that is 
based on ethical values and behaviour. 

l     The desirability of the Company maintaining a reputation for high standards of business conduct 

Our intention is to behave in a responsible manner, operating with a high standard of business conduct and corporate 
governance, as detailed in the Corporate Governance Report. 

l     The need to act fairly as between members of the Company 

The Board is fully committed to open and transparent dialogues with all shareholders. A supportive base of investors 
interested in a long-term holding in the Company provides the stability to allow us to execute our strategy and deliver long 
term value for all shareholders. We strive to engage with our investor base with meetings and updates to institutional and 
retail investors through a variety of channels. 

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  9

Outlook  
In the space of 12 months, SkinBioTherapeutics has managed to conduct and report on a ‘self-managed’ consumer study 
and prepare for the launch of its first product for sale.  

A key focus for the Group during the financial year 2022 will be raising awareness of AxisBiotix-Ps™ amongst the psoriatic 
communities and building market share, following its launch at the end of October. With the initial focus on the UK & US 
markets, attention will then turn to Europe and Asian markets, such as China and India.  

Building on the gut-skin axis research, the Group will look to finalise a similarly blended bacterial formulation to address 
acne, generate human data and push towards the commercial launch of a second AxisBiotix product. 

With  the  Croda/Sederma  partnership,  the  focus  for  2022  will  be  to  confirm  the  cosmetic  claims  for  the  SkinBiotix® 
technology as a cosmetic active ingredient and generate traction with Sederma’s key clients, with the aim of future potential 
revenue streams for SkinBioTherapeutics.  

2021 has been a transformational year for SkinBioTherapeutics despite a challenging environment, which is very much 
down to the expertise and dedication of the Group’s team and partners. We look forward to another exciting year in 2022.  

Stuart J. Ashman 
Chief Executive Officer 

29 November 2021 

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10  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Directors’ Report

The Directors present their report and the audited financial statements of the Group for the year ended 30 June 2021. 

Principal activity 
The principal activity of the Group is that of research and development focused on harnessing the microbiome for human 
health. 

Directors 
The directors who served the Company during the year were: 

Stuart J. Ashman 
Doug Quinn 
Martin Hunt 
Dr Cathy Prescott 

The Directors of the Company held the following beneficial interests in the share and share options of SkinBioTherapeutics 
plc at the date of this report: 

Issued share capital

Share options 

Ordinary shares Percentage 

of £0.01 each

Ordinary          Options 
shares of          exercise 
held £0.01 each                price 

Martin Hunt 

Stuart J. Ashman 

Doug Quinn 

Dr Cathy Prescott 

 466,667

 0.3% 

3,892,082               £0.09 

 125,000

 0.1% 

5,189,444               £0.09  
           & £0.18 

 439,474 

 0.3% 

2,594,721               £0.09 

 118,612 

 0.1%

–                        – 

Martin  Hunt’s  shareholding  is  held  through  Invictus  Management  Limited,  a  company  controlled  by  Mr  Hunt.  Of  the  466,667  shares  held  by  Invictus 
Management Limited 11,112 are held in trust for Louise Hunt and 11,111 are held in trust for Oliver Hunt. 

Substantial shareholdings  
As at 15 November 2021, the following interests in 3% or more of the issued share capital appear in the register: 

                                                                                                                                                                                                Percentage of 
                                                                                                                                                                                     issued share capital 

OptiBiotix Health Plc                                                                                                                                                                         20.7% 

Seneca Partners Limited                                                                                                                                                                     8.8% 

Tyndall Investment Management                                                                                                                                                      6.1% 

University of Manchester                                                                                                                                                                    5.1% 

Prof Catherine O’Neill                                                                                                                                                                         3.3% 

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  11

Directors remuneration 
The Directors received the following remuneration during the year: 

Executive                                                                  Salaries

      Share based                 Pension                        Total 
Fees           payments       contributions        remuneration 

Stuart Ashman                                                       £323,296

–               £43,899                   £5,523                £372,718 

Doug Quinn                                                             £12,851 

£116,600                 £4,340                   £3,198                £136,989 

Non-executive 

Martin Hunt                                                              £12,000 

£58,000                 £6,509                              –                  £76,509 

Dr Cathy Prescott                                                      £6,000 

£29,000                            –                              –                  £35,000 

                                                                              £354,147 

£203,600             £54,748                  £8,721              £621,216 

Financial instruments 
The Group’s exposure to financial risk is set out in note 2p) of the financial statements. 

Research and development 
The Strategic and Financial Review on pages 3-9 gives information of the Group’s research and development activities. 

Events after the reporting date 
Refer to note 21 to the financial statements for further details. 

Going concern 
The financial statements have been prepared on the assumption that the Group is a going concern. When assessing the 
foreseeable future, the Directors have considered the budget for the next 12 months from the date of this report and the 
cash at bank available as at the date of approval of this report and are satisfied that the Group should be able to meet its 
financial obligations. 

After making enquiries, the Directors have a reasonable expectation that the Group has adequate resources to continue in 
operational existence for the foreseeable future. Accordingly, they continue to adopt the going concern basis in preparing 
the annual report and financial statements. 

Statement of directors’ responsibilities 
The Directors are responsible for preparing the Strategic Report and Directors’ Report and the financial statements in 
accordance with applicable law and regulations. 

Company law requires the Directors to prepare financial statements for each financial year. Under that law the Directors 
have elected to prepare the financial statements in accordance with International Financial Reporting Standards (IFRSs) as 
adopted by the European Union. 

Under company law the Directors must not approve the financial statements unless they are satisfied that they give a true 
and fair view of the state of affairs and profit or loss of the Group for that period. In preparing these financial statements, 
the Directors are required to: 

l    select suitable accounting policies and then apply them consistently 

l    make judgements and accounting estimates that are reasonable and prudent 

l    state whether the Group and Parent Company financial statements have been prepared in accordance with applicable 
IFRSs as adopted by the European Union subject to any material departures disclosed and explained in the financial 
statements; and 

l    prepare the financial statements on the going concern basis unless it is inappropriate to presume that the Company will 

continue in business 

                                                                                                  
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12  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Directors’ Report (continued)

The Directors are responsible for keeping adequate accounting records that are sufficient to show and explain the Group’s 
transactions and disclose with reasonable accuracy at any time the financial position of the Group and the Company and 
enable them to ensure that the financial statements comply with the Companies Act 2006. They are also responsible for 
safeguarding the assets of the Group and the Company and hence for taking reasonable steps for the prevention and 
detection of fraud and other irregularities. The Directors confirm that: 

l    so far as each director is aware, there is no relevant audit information of which the Group’s auditor is unaware; and 

l    the Directors have taken all the steps that they ought to have taken as directors in order to make themselves aware of 

any relevant audit information and to establish that the Group’s auditor is aware of that information 

The Directors are responsible for the maintenance and integrity of the corporate and financial information included on the 
Company’s website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements 
may differ from legislation in other jurisdictions. 

Auditors 
Jeffrey’s Henry LLP has expressed their willingness to continue in office and a resolution to re-appoint them will be proposed 
at the forthcoming Annual General Meeting. 

This report was approved by the Board of Directors on 29 November 2021 and signed on its behalf by: 

Stuart J. Ashman 
Chief Executive Officer

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  13

Corporate Governance Report 

As Chairman of SkinBioTherapeutics I have overall responsibility for corporate governance and in promoting high standards 
throughout the Group. As well as leading and chairing the Board my responsibilities are to ensure; 

l    Committees are properly structured and operate with appropriate terms of reference 

l    The performance of individual directors, the Board and its committees are reviewed on a regular basis 

l    The Company has a coherent strategy and sets objectives against this 

l    There is effective communication between the Company and its shareholders 

All the directors of SkinBioTherapeutics believe strongly in the importance of good corporate governance for the creation 
of shareholder value over the medium to long-term and to engender trust and support amongst the Company’s wider 
stakeholders. The Board adopted the QCA code in September 2018 and considers that it does not depart from any of the 
principles of the QCA code. 

The QCA code is constructed around ten broad principles and a set of disclosures. The QCA has stated what it considers 
to be appropriate arrangements for growing companies and asks companies to provide an explanation about how they 
are meeting the principles through the prescribed disclosures. The Directors have considered how they apply each principle 
to the extent the Board judges these to be appropriate in the circumstances and below we provide an explanation of the 
approach taken in relation to each. There were no key governance related matters that occurred during the year. 

Martin Hunt, Chairman. 

Principle

Application 

Establish a strategy and business model which 
promotes long-term value for shareholders 

SkinBioTherapeutics  seeks  to  harness  the  microbiome  for  human 
health and has a particular focus on skin. The Group’s proprietary 
technologies are targeted at a number of health indications and the 
Company  is  progressing  applications  of  both  its  SkinBiotix®  and 
AxisBiotix™  technologies  as  a  route  to  initial  value  creation.  The 
Group’s  programme  of  research  and  development  is  intended  to 
build  long-term  shareholder  value  through  a  reliance  on  proven, 
rigorous science and the Group utilises its public listing as a means 
to source capital to support its R&D programme. 

The Group has an ongoing research agreement with the University of 
Manchester to identify and develop technologies. The Group has also 
leased laboratory space at the Biosphere in Newcastle upon Tyne to 
develop its own in-house scientific capability. In doing so the Group 
intends to avoid a reliance on a single technology and ensure that it 
has an ongoing pipeline of technologies, all related to the human 
microbiome, at different stages of development. The Group will seek 
to  licence  technologies  to  large  corporates  once  human  proof  of 
principle  has  been  established  and  intends  to  generate  licence 
revenue through this route. Where it considers it appropriate, the 
Company will also look to develop and market products. This is the 
case  with  AxisBiotix-Ps  where  the  Directors  believe  the  market 
opportunities in the UK, US and Europe are best developed by selling 
to consumers directly.

     
 
 
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14  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Corporate Governance Report (continued)

Principle

Application 

Seek  to  understand  and  meet  shareholder 
needs and expectations

The Board is committed to communicating openly with shareholders 
to ensure that its strategy and performance are clearly understood. 
Between  the  Chairman  and  the  executive  directors  an  open  and 
the  Company’s  major 
regular  dialogue 
shareholders which comprise; 

is  maintained  with 

Shareholder                                                   Holding 15 November 2021 

OptiBiotix Health Plc                                                                     20.7% 

Seneca Partners Limited                                                                 8.8% 

Tyndall Investment Management                                                  6.1% 

University of Manchester                                                                5.1% 

Prof Cath O’Neill                                                                               3.3% 

In November 2020, as part of share placing, Seneca Partners Limited 
and Tyndall Investment Management acquired 3.1m and 2.3m shares 
respectively. 

More generally the Board communicates with shareholders through 
the  Annual  Report  and  the  Interim  Statement,  trading  and  other 
announcements made on RNS and at the Annual General Meeting 
where the Board encourages investors to participate. The Company 
also  maintains  a  website,  www.skinbiotherapeutics.com,  which 
contains  information  on  the  Group’s  business  and  corporate 
information. Following the announcement of the Group’s half year 
and full year results the Chief Executive & CFO make presentations 
to institutional shareholders, private client brokers and investment 
analysts. Existing and prospective shareholders are able to separately 
contact the Chairman and Chief Executive via email as detailed on 
the Company’s website. Periodic meetings are held with existing and 
prospective  institutional  and  other  investors  and  the  Company 
presents at private investor investment events during the course of 
the  year.  The  Company’s  broker  also  produces  periodic  research 
notes on the Group.

     
 
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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  15

Principle

Application 

Take into account wider stakeholder and social 
responsibilities and their implications for long-
term success 

As  a  small  company  engaged  in  the  early  stages  of  technology 
development  the  Group  has  a  limited  but  important  number  of 
stakeholders. Robust science is at the core of the Group’s strategy and 
the Group has a number of key stakeholders, including its employees, 
involved in the different stages from research, through manufacture, 
formulation and testing. The Group assesses each of the companies 
it works with to ensure the requisite standards and values are in place. 
Ultimately the Group’s technology will be used by consumers and 
ensuring the appropriate development, manufacture and marketing 
of  products  will  be  key  to  the  long-term  success  of  the  Group. 
Throughout the various stages from initial technology identification 
to eventual product sales the Group is engaged in a continual process 
of  feedback  and  improvement  with  its  stakeholders,  including 
eventual end users. In addition, the eventual licensees of aspects of 
its technology will be important stakeholders in the interface with 
consumers and the longer-term success of the Group.

Embed effective risk management, considering 
both opportunities and threats, throughout the 
organisation 

Ultimate responsibility for the process by which risk in the business is 
managed rests with the Board. The Group’s internal risk identification 
and management process is as follows: 

l    The Executive Team prepares and reviews on a periodic basis the 
risk register for the Company. The risk register details specific risks 
to  the  Group,  the  quantification  of  those  risks  in  terms  of 
probability and impact, mitigating actions required to manage 
these  risks  and  the  control  mechanisms  that  are  in  place  to 
monitor the risks. 

l    The  risk  register  assigns  responsibility  for  each  risk  and  the 
mitigation plan to one or more members of the Executive Team. 

l    The  risk  register  is  circulated  to  the  Board  in  advance  of  each 
board meeting and specific risk items may be discussed at board 
meetings or otherwise as appropriate. 

l    The  risk  register  is  reported  to  the  Audit  Committee  at  least 

biannually.

     
 
     
 
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16  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Corporate Governance Report (continued)

Principle

Application 

Maintain  the  Board  as  a  well-functioning, 
balanced team led by the chair 

The  Board’s  primary  role  is  to  enhance  shareholders’  long-term 
interests by: 

l    determining the Group’s overall strategy and direction 

l    establishing and maintaining controls, audit processes and risk 
management policies to ensure they counter identified risks and 
that the Group operates efficiently 

l    ensuring effective corporate governance 

l    approving budgets and reviewing performance relative to those 

budgets 

l    approving financial statements 

l    approving material agreements and non-recurring projects  

l    approving senior and Board appointments 

Martin Hunt and Dr Cathy Prescott, both non-executive directors, are 
considered to be independent of the management and are free to 
exercise independence of judgement. 

The Non-Executive Directors are required to commit sufficient time as 
is  necessary,  approximately  two  days  per  month,  to  fulfil  their 
obligations.  Routine  commitments  include  preparation  for  and 
attendance  at  board  and  committee  meetings.  In  addition,  the 
Non-Executive Directors engage in ad-hoc dialogues with members of 
the Executive Team, shareholders and other stakeholders as required. 

All directors are subject to reappointment by shareholders at the first 
Annual General Meeting following their appointment and at each 
AGM thereafter. 

The table on page 22 details the attendance record of each director 
at board and committee meetings during the course of the year.

     
 
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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  17

Principle

Application 

Ensure  that  between  them  the  Directors  have 
the necessary up-to-date experience, skills and 
capabilities 

As  at  1  November  2021  the  board  comprised  an  independent 
non-executive  chairman, 
two  executive  directors  and  one 
independent non-executive director. One director is female and three 
are male.  

Martin Hunt, Independent Non-Executive Chairman 
Appointed as a director & Chairman in October 2016; Chair of the 
Remuneration  Committee  and  member  of  the  Audit  and  Insider 
Committees. 

Martin  has  had  a  long  executive  career  in  the  medtech  and  life 
science sectors including sales and general management roles with 
large corporations in Europe and the US. He was previously CEO of 
biomaterials company Tissue Science Laboratories plc taking it from 
start-up through an AIM listing and eventual sale to Covidien. More 
recently  he  has  held  a  number  of  non-executive  roles  with  both 
private and public companies. Martin is well versed in the early and 
growth  stages  of  companies  in  the  life  science  sector  as  well  as 
bringing  experience  of  corporate  governance  and  shareholder 
communications. 

Martin is the Medtech Industry Engagement Advisor to the National 
Institute  for  Health  Research  (HIHR)  and  a  member  of  the  NIHR 
strategy  board.  Martin  is  currently  Non-Executive  Chairman  of 
Videregen Limited. 

Time commitment of at least two days per month. 

Stuart Ashman, CEO 
Appointed as a director in April 2019 and CEO in July 2019. 

Stuart is an experienced commercial chief executive with considerable 
experience in the medtech and life science sectors. 

Prior to joining the Company, Stuart served as CEO of Onbone Oy 
(“Onbone”),  a  Finnish  private  equity-backed  medical  device 
company. In this role, he successfully established a global sales force 
and  distribution  network  and  led  the  growth  of  a  multi-million 
pound business. 

Prior to Onbone, Stuart was President/CEO of Andover Healthcare 
Inc., a US-based wound management manufacturer, and before then, 
was President/CEO of TI Group, a UK-based medical/engineering 
company. Stuart also served as Senior VP, Global Sales & Strategic 
Marketing,  BSN  Medical  (Biersdorf,  Smith  and  Nephew)  and  was 
Director  of  Sales  &  Marketing  at  Smith  &  Nephew  Plc,  in  its 
Woundcare,  Casting  &  Bandaging  division.  In  these  roles,  Stuart 
gained extensive experience of both direct sales management across 
multiple geographies, and of business to business selling. He has also 
been involved in M&A transactions and has achieved considerable 
commercial success in both small and large companies. 

Stuart is a full-time employee of the Company.

     
 
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18  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Corporate Governance Report (continued)

Principle

Application 

Doug Quinn, CFO 
Appointed as a director and CFO in December 2016 and Company 
Secretary  in  January  2017;  Member  of  the Audit  Committee  and 
Chair of the Insider Committee. 

Doug  has  been  involved  in  early  stage  companies  through  a 
combination of investor, executive and non-executive director and 
CFO roles for over 18 years. He was CFO of Arthro Kinetics Limited, 
an early stage tissue engineering company and part of the team that 
floated  the  Company  on  AIM  in  2006.  A  chartered  management 
accountant, with a number of years of experience in the life science 
sector, he brings financial expertise gained through executive roles 
and corporate finance transactions. 

Doug is a director and part-time CFO with the life science company 
Videregen Limited. 

Time commitment of approximately 3 days per week. 

Dr Catherine Prescott, Independent Non-Executive Director 
Appointed as a director in March 2017; Chair of the Audit Committee 
and member of the Remuneration Committee. 

Cathy  has  over  two  decades  of  experience  in  research  and 
management  in  the  biotech,  pharmaceutical  and  venture  capital 
sectors.  Cathy  is  a  visiting  professor  at  Kings  College  London, 
teaching on the MSc programme ‘Cellular Therapies from bench to 
market’. Cathy brings a broad range of scientific and strategic sector 
expertise and experience. 

Cathy is a non-executive director of Videregen Limited. 

Time commitment of two days per month. 

The Board has not, at this stage in its development, established a 
Nominations Committee. The Board as a whole continues to review 
its structure in order to provide what it considers to be an appropriate 
balance of executive and non-executive experience and skills. 

The  Board  believes  that  its  blend  of  relevant  experience,  skills, 
personal  qualities  and  capabilities  is  sufficient  to  enable  it  to 
successfully execute its strategy. The Board is additionally cognisant 
that with the recent changes to the Board and as the Company seeks 
to commercialise its technology, this may require additions to the 
Executive Team and wider Board. 

Directors attend seminars and other trade events to ensure that their 
knowledge remains current.

     
 
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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  19

Principle

Application 

Evaluate board performance based on clear and 
relevant  objectives, 
continuous 
improvement 

seeking 

Promote  a  corporate  culture  that  is  based  on 
ethical values and behaviours

On  the  formation  of  the  Board,  the  Directors  considered  the 
composition of the Audit Committee. Doug Quinn is an executive 
director  and  CFO  but  a  member  of  the  Committee  due  to  his 
experience  in  this  area.  Both  independent  directors  have  direct 
access to the auditors with the exclusion of Doug and vice versa and 
he is excused from any discussions where there is a potential conflict 
of interest.  

From time to time the Board may require third party advice on various 
matters  pertaining  to  its  business,  for  example  in  relation  to  the 
competitive  landscape.  Appropriate  relationships  to  source  such 
advice have been established. 

The  Directors  also  receive  regular  briefings  from  the  Company’s 
NOMAD in respect of continuing compliance with the AIM Rules.

included 

The Board designed and implemented an internal board evaluation 
exercise in 2020. The exercise was led by the Chairman and topics 
covered 
the  balance  of  skills,  experience  and 
independence,  understanding  of  the  business  and  its  strategy 
together  with  engagement  with  shareholders.  Each  director 
completed  a  questionnaire,  and  this  formed  the  basis  for  a 
subsequent discussion by the Board as a whole. 

Having repeated the process in 2021, the Board considers an internal 
evaluation appropriate and intends to repeat this process annually, 
acting on its findings as appropriate.  

The  Board’s  approach  to  succession  planning  is  based  upon 
identifying the medium to long term objectives of the Group and 
matching  these  against  the  competence  of  directors  and  senior 
managers. The Board will seek to identify potential gaps and recruit 
to fill these allowing a sufficient lead time.

The Board believes that the promotion of a corporate culture based 
on  sound  ethical  values  and  behaviours  is  essential  to  maximise 
shareholder value. The Board considers this particularly relevant to 
the Group in light of the partners with which it works, for example the 
University of Manchester, Croda Plc and Winclove Probiotics B.V., and 
recognising the intended end use of its technology in products to be 
marketed  to  and  purchased  by  consumers.  The  Executive  team 
engenders  open  and  positive  interactions  with  a  key  focus  on; 
scientific  rigour, 
innovation,  creative  solutions  and  collective 
responsibility. As the Group expands its human capability it will look 
to formalise its culture through an agreed set of values and standards.  

The Group’s policies set out its zero-tolerance approach towards any 
form of modern slavery, discrimination or unethical behaviour relating 
to bribery, corruption or business conduct.

     
 
     
 
     
 
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20  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Corporate Governance Report (continued)

Principle

Application 

Maintain governance structures and processes 
that  are  fit  for  purpose  and  support  good 
decision-making by the Board

Alongside setting the vision and strategy for the Group the Board is 
responsible to ensure that the business is managed for the long-term 
benefit  of  all  shareholders  whilst  having  regard  for  internal  and 
external stakeholders, including employees, customers and suppliers. 

The Board defines a series of matters reserved for its decision and 
has  approved  terms  of  reference  for  its  Audit,  Remuneration  and 
Insiders Committees to which certain responsibilities are delegated. 
The chair of each committee reports to the Board on the activities of 
that committee. 

The Audit Committee is responsible for: 

l    reviewing the annual financial statements and interim reports prior 

to approval 

l    reviewing and considering reports on internal financial controls, 

including reports from the auditors 

l    considering the appointment of and reviewing the relationship 
with  the  auditors,  including  reviewing  and  monitoring  of 
independence and objectivity 

l    reviewing the consistency of accounting policies 

l    considering any proposed related party transaction 

The Audit Committee can call for information from the Executive Team 
and consults with the external auditors directly when appropriate or 
when they are required to do so. 

The Remuneration Committee reviews and determines on behalf of 
the Board the pay, benefits and other terms of service of the Executive 
Directors of the Company. In addition, the Committee oversees the 
creation and implementation of all employee share plans. 

The Insider Committee is responsible for: 

l    monitoring and ensuring compliance with the Company’s MAR 

dealing policy 

l    reviewing  the  classification  of  employees,  directors  and  key 

consultants as regards clearance requirements 

l    reviewing and approving or rejecting as appropriate all requests 

for dealings in shares in the Company 

Matters reserved for the Board are; 

l    determining the Group’s overall strategy and direction 

l    establishing and maintaining controls, audit processes and risk 
management policies to ensure they counter identified risks and 
that the Group operates efficiently 

l    ensuring effective corporate governance 

l    approving budgets and reviewing performance relative to those 

budgets 

l    approving financial statements 

l    approving material agreements and non-recurring projects  

l    approving senior and Board appointments

     
 
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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  21

Principle

Application 

The Chairman has overall responsibility for corporate governance 
and in promoting high standards throughout the Group. As well as 
leading and chairing the Board, the Chairman’s responsibilities are 
to ensure; 

l    committees are properly structured and operate with appropriate 

terms of reference 

l    the  performance  of  individual  directors,  the  Board  and  its 

committees are reviewed on a regular basis 

l    the Company has a coherent strategy and sets objectives against 

this 

l    there is effective communication between the Company and its 

shareholders 

The  CEO  provides  coherent  leadership  and  management  of  the 
Group, 
leads  the  development  of  objectives,  strategies  and 
performance  standards  as  agreed  by  the  Board,  ensures  that  the 
assets of the Group are maintained and safeguarded, leads on investor 
relations  activities  to  ensure  communications  and  the  Company’s 
standing with shareholders and financial institutions is maintained. 

The Non-Executive Directors contribute independent thinking and 
judgement through the application of their external experience and 
knowledge,  scrutinise  the  performance  of  management,  provide 
constructive challenge to the executive directors and ensure that the 
Group  is  operating  within  the  governance  and  risk  framework 
approved by the Board. 

The Company Secretary is responsible for providing clear and timely 
information flow to the Board and its committees and supports the 
Board  on  matters  of  corporate  governance  and  risk.  This  role  is 
currently  filled  by  the  Group’s  CFO. The  Board  acknowledges  the 
QCA  guidelines  on  this  matter  and  consider  the  joint  roles 
appropriate  for  the  Company’s  size.  The  Company  Secretary  has 
direct access to the Chairman on matters of corporate governance.

     
 
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22  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Corporate Governance Report (continued)

Principle

Application 

Communicate  how  the  Company  is  governed 
and  is  performing  by  maintaining  a  dialogue 
with 
relevant 
stakeholders

shareholders 

and  other 

In addition to the investor relations activities described above the 
following committee reports are provided; 

The Audit  Committee,  which  comprises  Dr  Cathy  Prescott  (Chair), 
Martin Hunt and Doug Quinn, met three times during the course of 
the year. The Committee met with the external auditors prior to the 
approval  of  the  annual  accounts.  Consideration  was  given  to  the 
auditors’ pre and post audit reports and these provided opportunities 
to review the accounting policies, internal controls and the financial 
information contained within both the annual and interim reports. The 
Committee engaged the external auditors for a review of the interim 
statement prior to its release. 

The Remuneration Committee, which comprises Martin Hunt (Chair) 
and Dr Cathy Prescott met three times during the course of the year.  

Remuneration packages for the executive directors comprise a basic 
salary and performance related bonus. There is a defined pension 
contribution  scheme  in  place  for  all  directors  and  employees.  In 
addition, executive directors and senior employees participate in a 
share option long term incentive plan.  

The Committee reviewed the structure of remuneration packages for 
the executive directors and agreed they remained appropriate.  

In setting remuneration, the committee took into consideration the 
compensation packages of comparable AIM listed companies.  

The Insiders Committee, comprised of Doug Quinn (Chair) and Martin 
Hunt,  met  twice  during  the  course  of  the  year  to  review  the 
Company’s insider lists and review and approve requests for dealing 
in shares in the Company.  

For  information  regarding  the  voting  of  shareholders  at  general 
meetings of the Company please see the Shareholder Information 
section of the website.

                                          PLC board meetings                                                       Committee meetings 
                                                                                                      Audit                             Remuneration                          Insider 
                                       Eligible to      Attended     Eligible to      Attended     Eligible to      Attended    Eligible to      Attended 
Director                                attend                                   attend                                   attend                                  attend                          

Stuart Ashman                           10                   10                      –                      –                     –                      –                     –                      – 

Martin Hunt                                10                   10                     3                     3                     3                     3                     2                     2 

Dr Cathy Prescott                      10                   10                     3                     3                     3                     3                     –                      – 

Doug Quinn                               10                   10                     3                     3                     –                      –                     2                     2 

     
 
262369 SkinBio Therapeutics plc pp01-pp027.qxp  29/11/2021  10:19  Page 23

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  23

Independent Auditor’s Report to the Members of 
SkinBioTherapeutics Plc

Opinion 
We have audited the financial statements of SkinBioTherapeutics Plc for the year ended 30 June 2021 which comprise the 
consolidated statement of comprehensive income, the consolidated statement of financial position, the consolidated 
statement of cash flows, the consolidated statement of changes in equity, the company statement of financial position, the 
company statement of cash flows and the company statement of changes in equity and notes to the financial statements, 
including a summary of significant accounting policies.  

The financial reporting framework that has been applied in the preparation of the financial statements is applicable law and 
International Financial Reporting Standards (IFRSs) as adopted by the European Union. 

In our opinion:  

l the financial statements give a true and fair view of the state of the Group’s and Parent Company’s affairs as at 30 June 

2021 and of the Group’s loss for the year then ended;  

l the financial statements have been properly prepared in accordance with IFRSs as adopted by the European Union;  

l the financial statements have been prepared in accordance with the requirements of the Companies Act 2006. 

Basis for opinion 
We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our 
responsibilities under those standards are further described in the Auditor’s responsibilities for the audit of the financial 
statements section of our report. We are independent of the Company in accordance with the ethical requirements that 
are relevant to our audit of the financial statements in the UK, including the FRC’s Ethical Standard, and we have fulfilled 
our other ethical responsibilities in accordance with these requirements.  

We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion. 

Conclusions relating to going concern 
In auditing the financial statements, we have concluded that the director's use of the going concern basis of accounting in 
the preparation of the financial statements is appropriate. Our evaluation of the directors’ assessment of the entity’s ability 
to continue to adopt the going concern basis of accounting included reviews of expected cash flows for a period of 
12 months, to determine expected cash outflow, which was compared to the liquid assets held in the entity.  

Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions 
that, individually or collectively, may cast significant doubt on the group's ability to continue as a going concern for a period 
of at least twelve months from when the financial statements are authorised for issue. 

Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant 
sections of this report. 

Key audit matters 
Key audit matters are those matters that, in our professional judgment, were of most significance in our audit of the financial 
statements of the current period and include the most significant assessed risks of material misstatement (whether or not 
due to fraud) we identified, including those which had the greatest effect on: the overall audit strategy, the allocation of 
resources in the audit; and directing the efforts of the engagement team. These matters were addressed in the context of 
our audit of the financial statements as a whole, and in forming our opinion thereon, and we do not provide a separate 
opinion on these matters. This is not a complete list of all risks identified by our audit. 

262369 SkinBio Therapeutics plc pp01-pp027.qxp  29/11/2021  10:19  Page 24

24  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Independent Auditor’s Report to the Members of 
SkinBioTherapeutics Plc (continued)   

Key audit matter

Intangible assets 

The  Group  and  Company  had  capitalised  intellectual 
property  costs  amounting  to  £420,538  at  01  July  2020. 
During  the  year,  the  Group  and  Company  capitalised  a 
further  £108,403  (2020:  £73,668)  relating  to  intellectual 
property  costs.  These  capitalised  costs  are  not  yet  being 
amortised as the products are in development stage. 

The  Directors  have  assessed  whether  the  costs  meet  the 
criteria  for  capitalisation  and  whether  there  are  any 
indicators of impairment. 

The risk is that the costs may not qualify for capitalisation or 
technological advancements may render the market value 
of the capitalised costs below its carrying value. 

Profit after tax, which is considered by management to be a 
key  metric,  is  directly  impacted  by  the  amount  of  costs 
capitalised. 

How our audit addressed the key audit matter 

We have performed the following audit procedures: 

l considered  whether  the  nature  of  the  costs  met  the 
necessary  criteria  under  IAS  38  for  the  costs  to  be 
allowed for capitalisation; 

l vouched a sample of the costs capitalised to invoices, to 
confirm that they relate to intellectual property and have 
been accurately recorded; 

l considered  whether  the  Directors’  policy  for  the 
treatment  of  such  costs  was  reasonable  and  assessed 
whether the costs included in the reconciliation were in 
line with the Directors’ policy; 

l confirmed the directors’ assessment that no amortisation 

is necessary is accurate; and 

l reviewed cash flow forecasts for the foreseeable future 
to  assess  the  potential  future  economic  benefit  from 
ownership of the intangible assets. 

Based on the audit work performed we are satisfied, that 
although there are inherent uncertainties associated with the 
forecast and estimation of useful economic life of intangible 
assets,  the  directors  have  made  reasonable  assumptions 
about the valuation and useful economic life of intangible 
assets,  based  on  past  experience  and  expected  future 
revenues. We are also satisfied that all necessary disclosures 
have been made in the financial statements.

Our application of materiality 
The scope of our audit was influenced by our application of materiality. We set certain quantitative thresholds for materiality. 
These, together with qualitative considerations, helped us to determine the scope of our audit and the nature, timing and 
extent of our audit procedures on the individual financial statement line items and disclosures and in evaluating the effect 
of misstatements, both individually and in aggregate on the financial statements as a whole. 

Based on our professional judgment, we determined materiality for the financial statements as a whole as follows: 

Overall materiality

Group Financial Statements
£87,000 (2020: £75,000).

Company Financial Statements 
£86,000 (2020, £75,000) 

How we determined it

Based on 1.5% of gross assets 

Based on 1.5% of gross assets 

Rationale for
benchmark applied

We believe that gross assets is the primary  We believe that gross assets is the primary 
measure used by the shareholders in 
assessing the performance of the Company 
as revenue is yet to be generated.

measure used by the shareholders in  
assessing the performance of the Company 
as revenue is yet to be generated. 

We agreed with the Audit Committee that we would report to them misstatements identified during our audit for the Group 
£4,350 (2020: £3,750) and for the Company above £4,300 (2020: £3,750) as well as misstatements below those amounts 
that, in our view, warranted reporting for qualitative reasons. 

 
262369 SkinBio Therapeutics plc pp01-pp027.qxp  29/11/2021  10:19  Page 25

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  25

An overview of the scope of our audit 
As part of designing our audit, we determined materiality and assessed the risks of material misstatement in the financial 
statements. In particular, we looked at where the Directors made subjective judgments, for example in respect of significant 
accounting estimates that involved making assumptions and considering future events that are inherently uncertain. As in 
all of our audits we also addressed the risk of management override of internal controls, including evaluating whether there 
was evidence of bias by the Directors that represented a risk of material misstatement due to fraud. 

How we tailored the audit scope 

We tailored the scope of our audit to ensure that we performed enough work to be able to give an opinion on the financial 
statements as a whole, taking into account the structure of the Group and the Company, the accounting processes and 
controls, and the industry in which they operate.  

The Group financial statements are a consolidation of 2 reporting units, comprising the Group’s operating businesses and 
holding companies.  

We performed audits of the complete financial information of SkinbioTherapeutics Plc and AxisBiotix Limited reporting 
units, which were individually financially significant and accounted for 100% of the Group’s absolute loss before tax (i.e. the 
sum of the numerical values without regard to whether they were profits or losses for the relevant reporting units) and 100% 
of the Group’s assets and liabilities. We also performed specified audit procedures over certain account balances and 
transaction classes that we regarded as material to the Group at the 2 reporting units.  

We have audited all components within the Group, and no unaudited components remain. 

Other information 
The Directors are responsible for the other information. The other information comprises the information included in the 
annual report, other than the financial statements and our auditor’s report thereon. Our opinion on the financial statements 
does not cover the other information and, except to the extent otherwise explicitly stated in our report, we do not express 
any form of assurance conclusion thereon. 

In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing so, 
consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained 
in the audit or otherwise appears to be materially misstated. If we identify such material inconsistencies or apparent material 
misstatements, we are required to determine whether there is a material misstatement in the financial statements or a 
material misstatement of the other information. If, based on the work we have performed, we conclude that there is a material 
misstatement of this other information, we are required to report that fact. We have nothing to report in this regard. 

Opinions on other matters prescribed by the Companies Act 2006 
In our opinion, based on the work undertaken in the course of the audit: 

l    the information given in the strategic report and the Directors’ report for the financial year for which the financial 

statements are prepared is consistent with the financial statements; and 

l    the strategic report and the Directors’ report have been prepared in accordance with applicable legal requirements. 

Matters on which we are required to report by exception 
In the light of the knowledge and understanding of the Company and its environment obtained in the course of the audit, 
we have not identified material misstatements in the Strategic report nor the Directors’ report. 

We have nothing to report in respect of the following matters in relation to which the Companies Act 2006 requires us to 
report to you if, in our opinion: 

l    adequate accounting records have not been kept by the Company, or returns adequate for our audit have not been 

received from branches not visited by us; or 

262369 SkinBio Therapeutics plc pp01-pp027.qxp  29/11/2021  10:19  Page 26

26  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Independent Auditor’s Report to the Members of 
SkinBioTherapeutics Plc (continued)  

l    the financial statements are not in agreement with the accounting records and returns; or 

l    certain disclosures of Directors’ remuneration specified by law are not made; or 

l    we have not received all the information and explanations we require for our audit. 

Responsibilities of Directors 
As explained more fully in the Directors’ responsibilities statement set out on page 11, the Directors are responsible for the 
preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal control 
as  the  Directors  determine  is  necessary  to  enable  the  preparation  of  financial  statements  that  are  free  from  material 
misstatement, whether due to fraud or error. 

In preparing the financial statements, the Directors are responsible for assessing the Group’s and the Parent Company’s 
ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going 
concern basis of accounting unless the Directors either intend to liquidate the Group or the Parent Company or to cease 
operations, or have no realistic alternative but to do so. 

Auditor’s responsibilities for the audit of the financial statements 
Our objectives are to obtain reasonable assurance about whether the financial statements, as a whole, are free from material 
misstatement, whether due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance 
is a high level of assurance, but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect 
a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually 
or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of 
these financial statements. 

Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line 
with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including fraud. The 
extent to which our procedures are capable of detecting irregularities, including fraud, is detailed below. 

Explanation as to what extent the audit was considered capable of detecting irregularities, including fraud 

The objectives of our audit, in respect to fraud are; to identify and assess the risks of material misstatement of the financial 
statements  due  to  fraud;  to  obtain  sufficient  appropriate  audit  evidence  regarding  the  assessed  risks  of  material 
misstatements due to fraud, through designing and implementing appropriate responses; and to respond appropriately 
to fraud or suspected fraud identified during the audit. However, the primary responsibility for the prevention and detection 
of fraud rests with both those charged with governance of the entity and management.  

Our approach to identifying and assessing the risks of material misstatement in respect of irregularities, including fraud 
and non-compliance with laws and regulations, was as follows:  

l    the senior statutory auditor ensured the engagement team collectively had the appropriate competence, capabilities 

and skills to identify or recognise non-compliance with applicable laws and regulations;  

l    we  identified  the  laws  and  regulations  applicable  to  the  company  through  discussions  with  directors  and  other 

management, and from our knowledge and experience of the entity's activities.  

l    we focused on specific laws and regulations which we considered may have a direct material effect on the financial 
statements or the operations of the company, including Companies Act 2006, taxation legislation, data protection, 
employment and health and safety legislation.  

l    we assessed the extent of compliance with the laws and regulations identified above through making enquiries of 

management and reviewing legal expenditure; and  

l    identified laws and regulations were communicated within the audit team regularly and the team remained alert to 

instances of non-compliance throughout the audit. 

262369 SkinBio Therapeutics plc pp01-pp027.qxp  29/11/2021  10:19  Page 27

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  27

We  assessed  the  susceptibility  of  the  group’s  financial  statements  to  material  misstatement,  including  obtaining  an 
understanding of how fraud might occur, by: 

l    making enquiries of management as to where they considered there was susceptibility to fraud, their knowledge of 

actual, suspected and alleged fraud; and  

l    considering the internal controls in place to mitigate risks of fraud and non-compliance with laws and regulations. 

To address the risk of fraud through management bias and override of controls, we: 

l    performed analytical procedures to identify any unusual or unexpected relationships;  

l    tested journal entries to identify unusual transactions;  

l    assessed whether judgements and assumptions made in determining the accounting estimates were indicative of 

potential bias; and  

l    investigated the rationale behind significant or unusual transactions. 

In response to the risk of irregularities and non-compliance with laws and regulations, we designed procedures which 
included, but were not limited to: 

l    agreeing financial statement disclosures to underlying supporting documentation;  

l    reading the minutes of meetings of those charged with governance; and  

l    enquiring of management as to actual and potential litigation and claims 

There are inherent limitations in our audit procedures described above. The more removed that laws and regulations are 
from financial transactions, the less likely it is that we would become aware of non-compliance. Auditing standards also limit 
the audit procedures required to identify noncompliance with laws and regulations to enquiry of the directors and other 
management and the inspection of regulatory and legal correspondence, if any. 

Material misstatements that arise due to fraud can be harder to detect than those that arise from error as they may involve 
deliberate concealment or collusion. 

A further description of our responsibilities for the audit of the financial statements is located on the Financial Reporting 
Council’s website at: www.frc.org.uk/auditorsresponsibilities. 

This description forms part of our auditor’s report. 

Use of this report 
This report is made solely to the Company’s members, as a body, in accordance with Chapter 3 of Part 16 of the Companies 
Act 2006. Our audit work has been undertaken so that we might state to the Company’s members those matters we are 
required to state to them in an auditor’s report and for no other purpose. To the fullest extent permitted by law, we do not 
accept or assume responsibility to anyone other than the Company and the Company’s members as a body, for our audit 
work, for this report, or for the opinions we have formed. 

Sudhir Rawal (Senior Statutory Auditor) 
For and on behalf of 
Jeffreys Henry LLP, Statutory Auditor 
Finsgate 
5-7 Cranwood Street 
London EC1V 9EE 
29 November 2021

 
262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 28

28  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Consolidated Statement of Comprehensive Income  
For the Year Ended 30 June 2021 

Continuing operations 
Research and development
Operating expenses

Loss from operations
Finance costs

Loss before taxation
Taxation

Loss for the year
Other comprehensive income

Total comprehensive loss for the year

Basic and diluted loss per share (pence)

The notes on pages 35 to 52 form part of these financial statements.

Notes

2021
£

2020 
£ 

(505,627)
(991,481)

(1,497,108)
(926)

(1,498,034)
65,065

(1,432,969)
–

(635,226) 
(984,816) 

(1,620,042) 
– 

(1,620,042) 
119,956 

(1,500,086) 
– 

(1,432,969)

(1,500,086) 

(0.98)

(1.17) 

3
4

6

7

 
262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 29

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  29

Consolidated Statement of Financial Position 

As at 30 June 2021

ASSETS 
Non-current assets 
Property, plant and equipment
Right-of-use assets
Intangible assets

Total non-current assets

Current assets 
Other receivables
Corporation tax receivable
Cash and cash equivalents

Total current assets

Total assets

EQUITY AND LIABILITIES 
Equity 
Capital and reserves 
Called up share capital
Share premium
Other reserves
Accumulated deficit

Total equity

Liabilities 
Non-current liabilities 
Lease liabilities

Total non-current liabilities

Current liabilities
Trade and other payables
Lease liabilities

Total current liabilities

Total liabilities

Total equity and liabilities

Notes

2021
£

2020 
£ 

9
10
11

13
6, 13

–
143,328
528,941

672,269

1,700 
– 
420,538 

422,238 

268,946
183,828
4,609,889

70,622 
118,763 
2,159,054 

5,062,663

2,348,439 

5,734,932

2,770,677 

17
17

1,567,802
8,758,037
384,612
(5,495,193)

1,280,835 
4,923,890 
403,483 
(4,142,352) 

5,215,258

2,465,856 

15

114,780

14
15

114,780

379,820
25,074

404,894

519,674

– 

– 

304,821 
– 

304,821 

304,821 

5,734,932

2,770,677 

These financial statements were approved and authorised for issue by the Board of Directors on  29 November 2021 and 
were signed on its behalf by: 

Doug Quinn 
Director 

Company Registration No. 09632164 

The notes on pages 35 to 52 form part of these financial statements.

 
262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 30

30  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Consolidated Statement of Cash Flows  
For the Year Ended 30 June 2021 

Cash flows from operating activities 
Loss before tax for the period
Depreciation of property, plant and equipment
Right-of-use assets depreciation and interest
Share based payments charge

Changes in working capital 
(lncrease)/decrease in trade and other receivables
Increase in trade and other payables

Cash generated by/(used in) operations

Taxation received

Net cash used in operating activities

Investing activities 
Purchase of IP
Purchase of Right-of-Use Assets

Net cash used in investing activities

Cash flows from financing activities 
Net proceeds from issue of shares
Lease payments made

Net cash generated by financing activities

2021
£

2020 
£ 

(1,498,034)
1,700
3,355
61,257

(1,620,042) 
5,100 
– 
155,811 

(1,431,722)

(1,459,131) 

(198,324)
74,999

171,958 
183,487 

(123,325)

355,445 

–

211,544 

(1,555,047)

(892,142) 

(108,403)
(3,902)

(73,668) 
– 

(112,305)

(73,668) 

4,121,114
(2,927)

4,118,187

– 
– 

– 

Net (decrease)/increase in cash and cash equivalents

2,450,835

(965,810) 

Cash and cash equivalents at the beginning of the period

2,159,054

3,124,864 

Cash and cash equivalents at the end of the period

4,609,889

2,159,054 

The notes on pages 35 to 52 form part of these financial statements.

262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 31

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  31

Consolidated Statement of Changes in Equity  

For the Year Ended 30 June 2021

As at 1 July 2019
Loss for the period
Share-based payments

As at 30 June 2020
Loss for the period
Issue of shares
Costs of share issue
Exercise of share warrants
Share-based payments

As at 30 June 2021

Share
capital
£

Share
premium
£

1,280,835
–
–

1,280,835
–
286,967
–
–
–

4,923,890
–
–

4,923,890
–
4,242,189
(408,042)
–
–

Other
reserves
£

247,672
–
155,811

403,483
–
–
–
(80,128)
61,257

Retained
earnings
£

Total 
£ 

(2,642,266)
(1,500,086)
–

3,810,131 
(1,500,086) 
155,811 

(4,142,352)
(1,432,969)
–
–
80,128
–

2,465,856 
(1,432,969) 
4,529,156 
(408,042) 
– 
61,257 

1,567,802

8,758,037

384,612 (5,495,193) 5,215,258 

Share capital is the amount subscribed for shares at nominal value. 

Share premium is the amount subscribed for share capital in excess of nominal value. 

Other reserves arise from the equity element of a convertible loan issued and converted in the period to 30 June 2017, and 
from share options granted. 

Retained earnings represents accumulated profit or losses to date.  

The notes on pages 35 to 52 form part of these financial statements.

 
262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 32

32  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Company Statement of Financial Position 

As at 30 June 2021

ASSETS 
Non-current assets 
Property, plant and equipment
Right-of-use assets
Intangible assets
Investments
Other receivables

Total non-current assets

Current assets 
Other receivables
Corporation tax receivable
Cash and cash equivalents

Total current assets

Total assets

EQUITY AND LIABILITIES 
Equity 
Capital and reserves 
Called up share capital
Share premium
Other reserves
Accumulated deficit

Total equity

Liabilities 
Non-current liabilities 
Lease liabilities

Total non-current liabilities

Current liabilities 
Trade and other payables
Lease liabilities

Total current liabilities

Total liabilities

Total equity and liabilities

Notes

2021
£

2020 
£ 

9
10
11
12
13

13
6, 13

17
17

15

14
15

–
143,328
528,941
113,733
623,688

1,409,690

1,700 
– 
420,538 
5 
– 

422,243 

59,888
183,828
4,264,690

70,622 
118,763 
2,159,054 

4,508,406

2,348,439 

5,918,096

2,770,682 

1,567,802
8,758,037
384,612
(5,284,889)

1,280,835 
4,923,890 
403,483 
(4,142,352) 

5,425,562

2,465,856 

114,780

114,780

352,680
25,074

377,754

492,534

– 

– 

304,826 
– 

304,826 

304,826 

5,918,096

2,770,682 

No Statement of Comprehensive Income is presented in these financial statements for the Parent Company as provided by 
Section 408 of the Companies Act 2006. The loss for the financial year dealt with in the financial statements of the Parent 
Company was £1,222,665 (2020: £1,500,086). 

These financial statements were approved and authorised for issue by the Board of Directors on 29 November 2021 and 
were signed on its behalf by: 

Doug Quinn 
Director 

Company Registration No. 09632164 

The notes on pages 35 to 52 form part of these financial statements.

262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 33

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  33

Company Statement of Cash Flows  
For the Year Ended 30 June 2021 

Cash flows from operating activities 
Loss before tax for the period
Depreciation of property, plant and equipment
Right-of-use assets depreciation and interest
Impairment of financial assets
Share based payments charge

Changes in working capital 
Decrease in trade and other receivables
Increase in trade and other payables

Cash generated by operations

Taxation received

Net cash used in operating activities

Investing activities 
Purchase of IP
Investment in subsidiaries
Purchase of Right-of-Use Assets

Net cash used in investing activities

Financing activities 
Net proceeds from issue of shares
Lease payments made

Net cash generated by financing activities

2021
£

2020 
£ 

(1,287,730)
1,700
3,355
34,124
61,257

(1,620,042) 
5,100 
– 
– 
155,811 

(1,187,294)

(1,459,131) 

10,734
47,859

58,593

171,958 
183,492 

355,450 

–

211,544 

(1,128,701)

(892,137) 

(108,403)
(771,545)
(3,902)

(73,668) 
(5) 
– 

(883,850)

(73,673) 

4,121,114
(2,927)

4,118,187

– 
– 

– 

Net (decrease)/increase in cash and cash equivalents

2,105,636

(965,810) 

Cash and cash equivalents at the beginning of the period

2,159,054

3,124,864 

Cash and cash equivalents at the end of the period

4,264,690

2,159,054 

The notes on pages 35 to 52 form part of these financial statements.     

262369 SkinBio Therapeutics plc pp28-pp34.qxp  29/11/2021  10:20  Page 34

34  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Company Statement of Changes in Equity  

For the Year Ended 30 June 2021

As at 1 July 2019
Loss for the period
Share-based payments

As at 30 June 2020
Loss for the period
Issue of shares
Costs of share issue
Exercise of share warrants
Share-based payments

As at 30 June 2021

Share
capital
£

Share
premium
£

1,280,835
–
–

1,280,835
–
286,967
–
–
–

4,923,890
–
–

4,923,890
–
4,242,189
(408,042)
–
–

Other
reserves
£

247,672
–
155,811

403,483
–
–
–
(80,128)
61,257

Retained
earnings
£

Total 
£ 

(2,642,266)
(1,500,086)
–

3,810,131 
(1,500,086) 
155,811 

(4,142,352)
(1,222,665)
–
–
80,128
–

2,465,856 
(1,222,665) 
4,529,156 
(408,042) 
– 
61,257 

1,567,802

8,758,037

384,612 (5,284,889) 5,425,562 

Share capital is the amount subscribed for shares at nominal value. 

Share premium is the amount subscribed for share capital in excess of nominal value. 

Other reserves arise from the equity element of a convertible loan issued and converted in the period to 30 June 2017, 
and from share options granted. 

Retained earnings represents accumulated profit or losses to date.  

The notes on pages 35 to 52 form part of these financial statements.

 
262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 35

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  35

Notes to the Financial Statements  

For the Year Ended 30 June 2021

1 General information 
SkinBioTherapeutics plc (‘the Company’) is a public limited company incorporated in England under the Companies Act and 
quoted on the AIM market of the London Stock Exchange (AIM: SBTX). The address of its registered office is given on page 1. 

The  principal  activity  of  the  Group  is  the  identification  and  development  of  technology  that  harnesses  the  human 
microbiome to improve health. 

Significant accounting policies and basis of preparation 

2
a) Statement of compliance 
The consolidated and company financial statements of SkinBioTherapeutics plc have been prepared in accordance with 
International Financial Reporting Standards (‘IFRS’) as adopted by the European Union, IFRS Interpretations Committee 
(IFRIC) and the Companies Act 2006 applicable to companies reporting under IFRS. 

b) Basis of preparation 
The consolidated and company financial statements have been prepared under the historical cost convention modified by 
the revaluation of certain financial instruments. The accounting policies have been applied consistently in all material 
respects. 

The consolidated and company financial statements are presented in Sterling (£) as this is the predominant functional 
currency of the Group and Company, and is the currency of the primary economic environment in which it operates. Foreign 
transactions are accounted in accordance with the policies set out below. 

c) Basis of consolidation 
The consolidated financial statements incorporate the financial statements of the Company and entities controlled by the 
Company (its subsidiaries) made up to 30 June each year. Control is achieved where the Company has the power to govern 
the financial and operating policies of an investee entity so as to obtain benefits from its activities. 

All intra-group transactions, balances, income and expenses are eliminated on consolidation. 

d) Going concern 
These financial statements have been prepared on a going concern basis. In considering the appropriateness of this 
assumption, the Board has considered the Group’s projections for the twelve months from the date of approval of this 
financial information, including cash flow forecasts. The Directors believe that the Group has adequate resources to continue 
in operational existence for the foreseeable future and therefore adopt the going concern basis of accounting in preparing 
these financial statements. 

e) Estimates and judgements 
The preparation of financial statements requires the Board to make judgements, estimates and assumptions that may affect 
the application of accounting policies and reported amounts of assets and liabilities as at each balance sheet date and the 
reported amounts of revenues and expenses during each reporting period. Any estimates and assumptions are based on 
experience and any other factors that are believed to be relevant under the circumstances and which the Board considers 
to be reasonable. Actual outcomes may differ from these estimates. Any revisions to accounting estimates will be recognised 
in the period in which the estimate is revised if the revision affects only that period. If the revision affects both current and 
future periods, the change will be recognised over those periods. 

The following are the critical judgements that the Directors have made in the process of applying the Group’s accounting 
policies and that have the most significant effect on the amounts recognised in the consolidated financial statements. 

Estimation of the lifetime of intangible assets 
Intangible assets recognised are reviewed against the criteria for capitalisation with useful life determined by reference to 
the underlying product being developed. Management believes that the assigned values and useful lives, as well as the 
underlying assumptions, are reasonable, though different assumptions and assigned lives could have a significant impact 
on the reported amounts. 

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36  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

Significant accounting policies and basis of preparation (continued) 

2
e) Estimates and judgements (continued) 
Capitalisation of development costs 
During the year £108,403 (2020: £73,668) of development costs were capitalised, bringing the total amount of development 
costs capitalised, as intangible assets, as at 30 June 2021, to £528,941 (2020: £420,538), net of amortisation. Management 
has reviewed the balances by project, compared the carrying amount to expected future revenues and is satisfied that no 
impairment exists and that the costs capitalised will be fully recovered as the products are launched to market. New product 
projects are monitored regularly and should the technical or market feasibility of a new product be in question, the project 
would be cancelled and capitalised costs to date will be removed from the balance sheet and charged to the statement of 
comprehensive income. 

Share based payments 
The Group measures the cost of equity-settled transactions with employees by reference to the fair value of the equity 
instruments at the date at which they are granted. The fair value is determined by using the Black-Scholes model taking 
into account the terms and conditions upon which the instruments were granted. The accounting estimates and assumptions 
relating to equity-settled share-based payments would have no impact on the carrying amounts of assets and liabilities 
within the next annual reporting period but may impact profit or loss and equity. The judgments made and the model used 
are further specified in note 19. 

Estimate of incremental borrowing rate in accounting for leases under IFRS16 
In recognising a lease liability and right-of-use asset under IFRS 16 the Group has used an estimated incremental borrowing 
rate  of  8%. The  Group  does  not  have  any  borrowings,  so  in  order  to  apply  IFRS  16  it  was  necessary  to  estimate  the 
incremental borrowing rate that would be faced by the Group. The rate of 8% was determined by looking at a range of 
loans available on the market. If the interest rate used in the calculation were higher, this would have the effect of reducing 
the size of both the lease liability and right-of-use asset, reducing the depreciation charge and increasing the interest charge 
in the consolidated income statement. The overall change to the Consolidated Statement of Comprehensive Income and 
the  Consolidated  and  Company  Statement  of  Financial  Position  would  be  immaterial. There  would  be  no  change  to 
operating cash flows or lease payments as a result of a change in the estimate of the incremental interest rate. 

f) Application of new and revised International Financial Reporting Standards (IFRSs) 
No  new  standards  or  interpretations  issued  by  the  International  Accounting  Standards  Board  (‘IASB’)  or  the  IFRS 
Interpretations Committee (‘IFRIC’) have led to any material changes in the Group’s accounting policies or disclosures during 
each reporting period. 

New and revised IFRSs in issue but not yet effective 
There are a number of new and revised IFRSs that have been issued but are not yet effective that the Group has decided 
not to adopt early. The most significant of these are as follows: 

Reference                  Title                                                Summary

IFRS3                        Business Combinations           Amendments updating a reference
                                                                                      to the Conceptual Framework 

IFRS17                      Insurance contracts                  Principles for the recognition, measurement,
                                                                                      presentation and disclosure of insurance
                                                                                      contracts

                                                                                      Amendments to address concerns and
                                                                                      implementation challenges that were identified
                                                                                      after IFRS 17 was published

Application date of 
standard (Periods 
commencing on or after) 

1 January 2022 

1 January 2023 

1 January 2023 

                                                                                            
                                                                                            
 
 
 
 
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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  37

Reference                  Title                                                Summary

IAS1                          Presentation of                          Amendments regarding the classification of
                                  Financial Statements                liabilities

                                                                                      Amendment to defer the effective date of the
                                                                                      January 2020 amendments

                                                                                      Amendments regarding the disclosure of
                                                                                      accounting policies

IAS8                          Accounting Policies,                Amendments regarding the definition of
                                  Changes in Accounting          accounting estimates 
                                  Estimates and Errors 

Application date of 
standard (Periods 
commencing on or after) 

1 January 2023 

1 January 2023 

1 January 2023 

1 January 2023 

The adoption of these Standards and Interpretations is not expected to have a material impact on the financial information 
of the Group in the period of initial application when they come into effect. 

g) Foreign currencies 
Transactions in foreign currencies are translated at the exchange rate ruling at the date of the transaction. Monetary assets 
and liabilities denominated in foreign currencies at the balance sheet date are translated at the exchange rate ruling at that 
date. Foreign exchange differences on translation are recognised in the income statement. Non-monetary assets and 
liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the 
date of the transaction. Non-monetary assets and liabilities denominated in foreign currencies that are stated at fair value 
are translated at foreign exchange rates ruling at the dates the fair value was determined. 

h) Research and development 
Research  expenditure  is  written  off  to  the  statement  of  comprehensive  income  in  the  year  in  which  it  is  incurred. 
Development expenditure is written off in the same way unless the directors are satisfied as to the technical, commercial 
and financial viability of individual projects. In this situation, the expenditure is deferred and amortised over the period 
during which the Group is expected to benefit. 

i) Property, plant and equipment 
Property, plant and equipment are stated at historical cost less subsequent accumulated depreciation and accumulated 
impairment losses, if any. Historical cost includes expenditure that is directly attributable to the acquisition of the items. 

Subsequent costs are included in the asset’s carrying amount or recognised as a separate asset, as appropriate, only when 
it is probable that future economic benefits associated with the item will flow to the Group and the cost of the item can be 
measured reliably. All other repairs and maintenance are charged to profit or loss during the financial period in which they 
are incurred. 

Depreciation on property, plant and equipment is calculated using the straight-line method to write off their cost over their 
estimated useful lives at the following annual rates: 

Plant & machinery 50% 

Useful lives and depreciation method are reviewed and adjusted if appropriate, at the end of each reporting period. 

                                                                                            
                                                                                            
 
 
 
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38  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

Significant accounting policies and basis of preparation (continued) 

2
i) Property, plant and equipment (continued) 
An item of property, plant and equipment is derecognised upon disposal or when no future economic benefits are expected 
to arise from the continued use of the asset. Any gain or loss arising on the disposal or retirement of an item of property, 
plant and equipment is determined as the difference between the sales proceeds and the carrying amount of the relevant 
asset, and is recognised in profit or loss in the year in which the asset is derecognised. 

Impairment testing of intangible assets 

j)
At the end of each reporting period, the Group reviews the carrying amounts of its intangible assets to determine whether 
there is any indication that those assets have suffered an impairment loss. If any such indication exists, the recoverable 
amount of the asset is estimated to determine the extent of the impairment loss (if any). 

Intangible assets with indefinite useful lives are tested for impairment at least annually, and whenever there is an indication 
that the assets may be impaired. 

k) Leasing 
At inception of a contract, the Group assesses whether a contract is, or contains, a lease. 

A lease is defined as ‘a contract, or part of a contract, that conveys the right to use an asset (the underlying asset) for a 
period of time in exchange for consideration’. To apply this definition the Group assesses whether each of the following 
criteria apply: 

l       the contract contains an identified asset, which is either explicitly identified in the contract or implicitly specified by 

being identified at the time the asset is made available to the Group; 

l       the Group has the right to obtain substantially all of the economic benefits from use of the identified asset throughout 

the period of use, considering its rights within the defined scope of the contract; and 

l       the Group has the right to direct the use of the identified asset throughout the period of use. The Group assesses 

whether it has the right to direct ‘how and for what purpose’ the asset is used throughout the period of use. 

Measurement and recognition of leases as a lessee 
At the commencement date of a lease, the Group recognises a right-of-use asset and a lease liability on the balance sheet. 
The right-of-use asset is measured at cost, which is made up of the initial measurement of the lease liability, any initial direct 
costs incurred by the Group, an estimate of any costs to dismantle and remove the asset at the end of the lease, and any 
lease payments made in advance of the lease commencement date, net of any incentives received. 

The Group depreciates right-of-use assets on a straight-line basis from the lease commencement date to the earlier of the 
end of the useful life of the right-of-use asset or the end of the lease term. The Group also assesses the right-of-use asset 
for impairment when indicators of impairment exist. 

At the commencement date of a lease, the Group measures the lease liability at the present value of the lease payments 
unpaid at that date, discounted using the interest rate implicit in the lease if that rate is readily available, or the Group’s 
incremental borrowing rate. Details of this borrowing rate are given in note 2e. 

Lease payments included in the measurement of the lease liability are made up of fixed payments (including in substance 
fixed), variable payments based on an index or rate, amounts expected to be payable under any residual value guarantees 
and payments arising from options reasonably certain to be exercised. 

Subsequent to initial measurement, the liability is reduced for payments made and increased for interest. It is remeasured 
to reflect any reassessment or modification, or if there are changes in in-substance fixed payments. If a lease liability is 
remeasured, a corresponding adjustment is reflected in the value of the right-of-use asset, or, if the carrying value of the 
right-of-use asset is already reduced to zero, the income statement. 

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  39

The Group has elected to account for short-term leases (with a term of up to 12 months) and leases of low-value assets 
using the practical expedients available in IFRS 16. Instead of recognising a right-of-use asset and lease liability, the payments 
in relation to such leases are recognised as an expense in the income statement on a straight-line basis over the lease term. 

l) Tax 
Current tax 
The tax currently payable is based on taxable profit for the period. Taxable profit differs from ‘profit before tax’ as reported 
in the income statement because of items of income or expense that are taxable or deductible in other periods and items 
that are never taxable or deductible. The Group’s current tax is calculated using rates that have been enacted during the 
reporting period. 

Deferred tax 
Deferred tax is provided using the balance sheet liability method, providing for temporary differences between the carrying 
amounts of assets and liabilities for financial reporting purposes and the amounts used for tax purposes. The amount of 
deferred tax provided is based on the expected manner of realisation or settlement of the carrying amount of assets and 
liabilities, using tax rates enacted or substantively enacted at the balance sheet date. 

A deferred tax asset is recognised only if it can be regarded as more likely than not that there will be suitable taxable profits 
from which the future reversal of the underlying temporary differences can be deducted. 

m) Payroll expense and related contributions 
Wages, salaries, payroll tax, paid annual leave and sick leave, bonuses, and non-monetary benefits are accrued in the period 
in which the associated services are rendered. 

n) Share-based compensation 
The Group issues share based payments to certain directors and others providing similar services. The fair value of the 
employee and suppliers services received in exchange for the grant of the options is recognised as an expense. The total 
amount to be expensed over the vesting year is determined by reference to the fair value of the options granted, excluding 
the impact of any non-market vesting conditions (for example, profitability and sales growth targets). Nonmarket vesting 
conditions are included in assumptions about the number of options that are expected to vest. At each statement of financial 
position date, the entity revises its estimates of the number of options that are expected to vest. It recognises the impact of 
the revision to original estimates, if any, in the income statement, with a corresponding adjustment to equity. 

The proceeds received net of any directly attributable transaction costs are credited to share capital (nominal value) and 
share premium when the options are exercised. 

The fair value of share-based payments recognised in the income statement is measured by use of the Black Scholes model, 
which takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used 
in the model is adjusted; based on management’s best estimate, for the effects of non-transferability, exercise restrictions 
and  behavioural  considerations.  The  share  price  volatility  percentage  factor  used  in  the  calculation  is  based  on 
management’s best estimate of future share price behaviour and is selected based on past experience, future expectations 
and benchmarked against peer companies in the industry. 

o) Financial assets and liabilities 
Financial assets and liabilities are recognised when the Group unconditionally becomes a party to the contractual terms of 
the instrument. Unless otherwise indicated, the carrying amounts of financial assets and liabilities are considered by the 
directors to be a reasonable estimate of their fair values at each balance sheet date. 

Financial assets include trade and other receivable; these are classified as loans and receivables. Financial liabilities include 
trade and other payables, convertible loan notes and borrowings; these are classified as other financial liabilities carried at 
amortised cost.

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40  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

Significant accounting policies and basis of preparation (continued) 

2
o) Financial assets and liabilities (continued)  
Classification as debt or equity 
Debt and equity instruments issued by the Group are classified as either financial liabilities or as equity in accordance with 
the substance of the contractual arrangements and the definitions of a financial liability and an equity instrument. 

Equity instruments 
An equity instrument is any contract that evidences a residual interest in the assets of an entity after deducting all of its 
liabilities. Equity instruments issued by the Group are recognised as the proceeds received, net of direct issue costs. 

Derecognition 
Financial assets are derecognised when rights to receive cash flows from the assets expire or, the financial assets are 
transferred and the Group has transferred substantially all the risks and rewards of ownership of the financial assets. On 
derecognition of a financial asset, the difference between the asset’s carrying amount and the sum of the consideration 
received and receivable and the cumulative gain or loss that had been recognised in other comprehensive income and 
accumulated in equity is recognised in profit or loss. 

Financial liabilities are derecognised when the obligation specified in the relevant contract is discharged, cancelled or 
expires. The difference between the carrying amount of the financial liability derecognised and the consideration paid and 
payable is recognised in profit or loss. 

When the terms of a financial liability are renegotiated and result in the Group issuing equity instruments to a creditor of 
the Group to extinguish all or part of the financial liability, the Group recognises the issue of equity instruments at their fair 
values. Any difference between the fair value of the equity instruments and the carrying amount of the financial liability to 
be extinguished is recognised in the income statement. 

Trade and other receivables 
Trade and other receivables are recognised initially at their fair value and subsequently at their amortised cost using the 
effective interest method, less provision for impairment. If there is objective evidence that the recoverability of the asset is 
at risk, appropriate allowances for any estimated irrecoverably amounts are recognised in the income statement. 

Intercompany receivables 
Amounts owed by subsidiary undertakings represent loans made to the Company’s main subsidiary on an interest-free 
basis. No repayment terms have been mandated. 

IFRS 9’s impairment requirements use forward-looking information to recognise expected credit losses – the ‘expected 
credit loss (ECL) model’. 

The Group considers a broad range of information when assessing credit risk and measuring expected credit losses, 
including past events, current conditions, reasonable and supportable forecasts that affect the expected collectability of 
the future cash flows of the instrument. 

In applying this forward-looking approach, a distinction is made between: 

l       financial instruments that have not deteriorated significantly in credit quality since initial recognition or that have low 

credit risk (‘Stage 1’) 

l       financial instruments that have deteriorated significantly in credit quality since initial recognition and whose credit risk 

is not low (‘Stage 2’) 

l       financial assets that have objective evidence of impairment at the reporting date (‘Stage 3’) 

‘12-month expected credit losses’ are recognised for ‘Stage 1’ financial instruments, while ‘lifetime expected credit losses’ 
are recognised for ‘Stage 2’ financial instruments. Measurement of the expected credit losses is determined by a probability 
weighted estimate of credit losses over the expected life of the financial instrument. 

The Group considers that the current intercompany loan should be recognised as Stage 1, and 12-month expected credit 
losses have been calculated.

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  41

Cash and cash equivalents 
Cash and cash equivalents comprise cash in hand. 

Trade and other payables 
Trade and other payables are recognised initially at their fair value, net of transaction costs, and subsequently at their 
amortised cost using the effective interest method. 

p) Financial risk management 
Risk management objectives 
Management identify and evaluate financial risks on an on-going basis. The principal risks to which the Group is exposed 
are market risk (including interest rate risk, and cash flow risk), credit risk, and liquidity risk. 

Market risk 
Market risk is defined as the risk that the fair value of future cash flows of a financial instrument will fluctuate because 
of  changes  in  market  prices. The  Group’s  market  risks  arise  from  open  positions  in  (a)  interest-bearing  assets  and 
liabilities, and (b) foreign currencies; to the extent that these are exposed to general and specific market movements 
(see details below). 

Interest rate risk 
The Group’s interest-bearing assets comprise of only cash and cash equivalents. As the Group’s interest-bearing assets do 
not generate significant amounts of interest; changes in market interest rates do not have any significant direct effect on 
the Group’s income. 

Currency risk 
The Group is exposed to movement in foreign currency exchange rates arising from normal trading transactions that are 
denominated in currencies other than the respective functional currencies of the Group. The Group does not have a policy 
to hedge its exposure to foreign currency exchange risk as currently overseas transactions are only a small percentage of 
total transactions and fluctuations in foreign currencies are not expected to significantly affect the Group’s total transactions. 
In future the Group may consider hedging its exposure to foreign currency exchange risk. 

Credit risk 
Credit risk refers to the risk that a counterparty will default on its contractual obligations resulting in financial loss to the 
Group. Credit risk arises from cash balances (including bank deposits, cash and cash equivalents) and credit exposures to 
trade receivables. The Group’s maximum exposure to credit risk is represented by the carrying value of cash and cash 
equivalents and trade receivables. Credit risk is managed by monitoring clients and performing credit checks before 
accepting any customers. 

Liquidity risk 
Liquidity risk is the risk that the Group may encounter difficulty in meeting its obligations associated with financial liabilities 
that are settled by delivering cash or other financial assets. 

The Group seeks to manage its liquidity risk by ensuring that sufficient liquidity is available to meet its foreseeable needs. 

q) Capital management 
The Group manages its capital to ensure that it will be able to continue as a going concern while maximising the return to 
stakeholders. The Group’s overall strategy remained unchanged during the period. 

The capital structure of the Group consists of cash and cash equivalents, issued capital, the share premium account, the 
share-based compensation reserve resulting from the grant of equity-settled share options to selected directors and others 
providing similar services, and retained earnings. 

The Group is not subject to any externally imposed capital requirements. 

As part of the Group’s management of capital structure, consideration is given to the cost of capital. 

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42  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

3 Operating loss 
An analysis of the Group’s operating loss has been arrived at after charging/(crediting): 

Other income
Research and development
Directors’ remuneration (including share-based
compensation and excluding share issue costs) 
Auditor’s remuneration 
    – audit fees
    – other services
Foreign exchange differences
Impairment of other receivables
Other operating costs

2021
£

(137)
505,627
577,216

17,000
3,200
2,755
–
391,447

Group 

2020 
£ 

(52) 
635,226 
507,467 

11,100 
1,850 
(3) 
– 
464,454 

Total operating expenses

1,497,108

1,620,042 

The Group has one reportable segment, namely that of identifying and developing formulations that harness the human 
microbiome, all within the United Kingdom. 

4

Finance costs 

Interest payable

Interest payable represents amounts arising on leases accounted for under IFRS 16. 

Employees and Directors 

5
Group and company 
The average monthly number of employees and senior management was: 

Executive directors
Non-executive directors
Employees

Average total persons employed

As at 30 June 2021 the Company had 7 employees (2020: 7). 

Group 

2021
£

926

926

2020 
£ 

– 

– 

2021
Number

 2020 
Number 

2
2
3

7

2 
2 
3 

7 

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SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  43

Group and company 
Staff costs in respect of these employees were: 

Wages and salaries
Social security costs
Defined contribution pensions
Share-based payments (see note 19)

Total remuneration

2021
£

561,762
65,408
12,218
61,257

700,645

2020 
£ 

450,863 
52,250 
6,140 
155,811 

665,064 

All staff were directly employed by SkinBioTherapeutics Plc. 

Some of these staff costs are included within research and development and some in share issue costs. 

All the directors above can be considered to be key management and have the responsibility for planning, directing and 
controlling, directly or indirectly, the activities of the Group. 

The remuneration of directors and key executives is determined by the remuneration committee having regard to the 
performance of individuals and market trends. 

The Group operates a defined contribution pension scheme for employees and directors. The assets of the scheme are 
held separately from those of the Group in independently administered funds. The amounts outstanding at 30 June 2021 
are £1,650 (2020: £3,559). 

Group and company 
Directors’ remuneration: 

Stuart J. Ashman
Doug Quinn
Martin Hunt
Dr Cathy Prescott

Total remuneration

Which is made up of: 

Remuneration
Amounts receivable under long term incentive schemes
Company contributions to pension schemes

Total remuneration

2021
£

372,718
136,989
76,509
35,000

621,216

557,747
54,748
8,721

621,216

2020 
£ 

276,294 
130,986 
72,537 
27,650 

507,467 

424,112 
80,598 
2,757 

507,467 

The  number  of  directors  to  whom  retirement  benefits  are  accruing  in  respect  of  qualifying  services  under  defined 
contribution pension schemes is 2 (2020: 2). The highest paid director received total emoluments of £372,718 (2020: 
£276,294) during the year. 

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44  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

Taxation 

6
Income taxes recognised in profit or loss 

Current tax 
Current period – UK corporation tax
R&D tax credit
R&D tax credit – prior year

Tax credit for the year

Group 

2021
£

2020 
£ 

–
67,294
(2,229)

– 
118,763 
1,193 

65,065

119,956 

The tax charge for each period can be reconciled to the loss per the statement of comprehensive income as follows: 

Loss on ordinary activities before tax
Normal applicable rate of tax
Loss on ordinary activities multiplied by normal rate of tax
Effects of: 
Depreciation
Disallowables
R&D enhanced deductions
R&D tax credit
Losses surrendered
Unused tax losses carried forward

UK tax charge/(credit)

(1,498,034)
19.00%
(284,626)

(1,620,042) 
19.00% 
307,808 

323
12,015
(67,899)
(65,065)
88,179
252,008

– 
30,231 
(87,959) 
(119,956) 
155,621 
209,915 

(65,065)

(119,956) 

The Group has an unrecognised deferred tax asset of £759,472 (2020: £507,162) at the period end, which has not been 
recognised in the financial statements due to uncertainty of future profits. The Group has an estimated tax loss of £3,997,223 
(2020: £2,669,276) available to be carried forward against future profits. 

7

Loss per share 

Basic and diluted loss per share 
Loss after tax (£)
Weighted average number of shares

Basic and diluted loss per share (pence)

Group 

2021
£

2020 
£ 

(1,432,969)
146,697,033

(1,500,086) 
128,083,494 

(0.98)

(1.17) 

As the Group is reporting a loss from continuing operations for the year then, in accordance with IAS 33, the share options 
are not considered dilutive because the exercise of the share options would have an anti-dilutive effect. The basic and 
diluted earnings per share as presented on the face of the income statement are therefore identical.

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 45

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  45

Company’s result for the period 

8
The Group has elected to take the exemption under section 408 of the Companies Act 2006 not to present the Parent 
Company income statement account. 

The loss for the Parent Company for the period was £1,222,665 (2020: £1,500,086). 

9

Property, plant and equipment 

Cost 
At 1 July 2019
Additions

At 30 June 2020
Additions

At 30 June 2021

Accumulated amortisation 
At 1 July 2019
Charge for the period

At 30 June 2020
Charge for the period

At 30 June 2021

Net book value 
At 1 July 2019

At 30 June 2020

At 30 June 2021

10 Right-of-use assets 

Cost 
At 1 July 2019
Additions

At 30 June 2020
Additions

At 30 June 2021

Accumulated amortisation 
At 1 July 2019
Charge for the period

At 30 June 2020
Charge for the period

At 30 June 2021

Net book value 
At 1 July 2019

At 30 June 2020

At 30 June 2021

Group
£

10,200
–

10,200
–

10,200

3,400
5,100

8,500
1,700

Company 
£ 

10,200 
– 

10,200 
– 

10,200 

3,400 
5,100 

8,500 
1,700 

10,200

10,200 

6,800

1,700

–

6,800 

1,700 

– 

Group
£

Company 
£ 

–
–

– 
– 

–
145,757

– 
145,757 

145,757

145,757 

–
–

–
2,429

2,429

–

–

– 
– 

– 
2,429 

2,429 

– 

– 

143,328

143,328

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 46

46  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

11 Intangible assets 

Cost 
At 1 July 2019
Additions

At 30 June 2020
Additions

At 30 June 2021

Accumulated amortisation
At 1 July 2019
Charge for the period

At 30 June 2020
Charge for the period

At 30 June 2021

Net book value
At 1 July 2019

At 30 June 2020

At 30 June 2021

Group
£

Company 
£ 

346,870
73,668

420,538
108,403

346,870 
73,668 

420,538 
108,403 

528,941

528,941 

–
–

–
–

–

– 
– 

– 
– 

– 

346,870

420,538

346,870 

420,538 

528,941

528,941 

Intellectual property is to be amortised over the expected period that the asset generates income and is expected to 
commence in the year ending 30 June 2022. 

12 Investments 
Company: Investments in subsidiary undertakings

Cost 
At 1 July 2019
Additions

At 30 June 2020
Additions

At 30 June 2021

£ 

– 
5 

5 
113,728 

113,733 

As at 30 June 2021, the Company directly owned the following subsidiaries: 

Name of company                                     Country of incorporation                           Proportion of equity interest 

SkinBiotix Limited                                      United Kingdom                                          100% of ordinary shares 
AxisBiotix Limited                                      United Kingdom                                          100% of ordinary shares 
CleanBiotix Limited                                   United Kingdom                                          100% of ordinary shares 
MediBiotix Limited                                    United Kingdom                                          100% of ordinary shares 
PharmaBiotix Limited                                United Kingdom                                          100% of ordinary shares

 
 
262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 47

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  47

13 Trade and other receivables 

Current 
Corporation tax
VAT recoverable
Other receivables
Prepayments

Non-current 
Amounts due from group undertakings

Group

2021
£

Company 

2020
£

2021
£

2020 
£ 

183,828
19,597
10,000
239,349

118,763
22,462
150
48,010

183,828
7,793
10,000
42,095

118,763 
22,462 
150 
48,010 

452,774

189,385

243,716

189,385 

–

–

–

–

623,688

623,688

– 

– 

The fair values of the Company’s current trade and other receivables are considered to equate to their carrying amounts. 
The maximum exposure to credit risk for trade receivables is represented by their carrying amount. There are no financial 
assets which are past due but not impaired. No current financial assets are impaired. 

The amounts owed by subsidiary undertakings include a loan to AxisBiotix Limited for £771,544 (2020: £nil) which was 
discounted to £657,812 and then impaired by £34,124 to £623,688 under IFRS 9, as set out in note 2. There is no interest 
payable on this loan which is assumed to be payable in 2023. The Parent Company has confirmed that it does not intend to 
seek repayment of the loan balance for at least twelve months from the date of these financial statements.  

14 Trade and other payables 

Current 
Trade creditors
Accruals
Other taxes
Amounts due to group undertakings
Other payables

Group

2021
£

Company 

2020
£

2021
£

2020 
£ 

78,842
279,922
17,726
–
3,330

138,571
147,019
15,548
–
3,683

71,352
260,272
17,726
–
3,330

138,571 
147,019 
15,548 
5 
3,683 

379,820

304,821

352,680

304,826 

Trade and other payables principally consist of amounts outstanding for trade purchases and ongoing costs. They are non-
interest bearing and are normally settled on 30-day terms. The directors consider that the carrying value of trade and other 
payables approximates to their fair value. All trade and other payables are denominated in Sterling. The Company has 
financial risk management policies in place to ensure that all payables are paid within the credit timeframe and no interest 
has been charged by any suppliers as a result of late payment of invoices during the period. 

The fair value of trade and other payables approximates their current book values. 

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 48

48  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

15 Lease liabilities 

Group and company

Maturity analysis 
Year 1
Year 2
Year 3
Year 4
Year 5

Less future interest charges

Analysed as 
Current
Non-current

2021
£

2020 
£ 

35,122
32,195
33,989
35,122
32,195

168,623
(28,769)

139,854

25,074
114,780

139,854

– 
– 
– 
– 
– 

– 
– 

– 

– 
– 

– 

16 Financial instruments 
Maturity analysis 
A summary table with maturity of financial assets and liabilities presented below is used by management to manage liquidity 
risks. The amounts disclosed in the following tables are the contractual undiscounted cash flows. Undiscounted cash flows 
in respect of balances due within 12 months generally equal their carrying amounts in the statement of financial position, 
as the impact of discounting is not material. 

The maturity analysis of financial instruments at 30 June 2021 is as follows: 

Group

Assets 
Cash and cash equivalents
Trade and other receivables

Liabilities 
Trade and other payables
Lease Liabilities

On demand 
Carrying and less than
3 months
amount
£
£

3 to 12
months 1 to 2 years
£

£

2 to 5 years 
£ 

4,609,889
213,425

4,609,889
213,425

4,823,314

4,823,314

–
–

–

–
–

–

– 
– 

– 

362,094
168,623

362,094
8,781

530,717

370,875

–
26,341

26,341

–
32,195

– 
101,306 

32,195

101,306 

 
262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 49

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  49

Company

Assets 
Cash and cash equivalents
Trade and other receivables

Liabilities 
Trade and other payables
Lease Liabilities

On demand 
Carrying and less than
3 months
amount
£
£

3 to 12
months 1 to 2 years
£

£

2 to 5 years 
£ 

4,264,690
973,165

4,264,690
201,621

5,237,855

4,466,311

–
–

–

–
771,544

771,544

– 
– 

– 

334,954
168,623

334,954
8,781

503,577

343,735

–
26,341

26,341

–
32,195

– 
101,306 

32,195

101,306 

The maturity analysis of financial instruments at 30 June 2020 is as follows: 

Group

Assets 
Cash and cash equivalents
Trade and other receivables

Liabilities 
Trade and other payables

Company

Assets 
Cash and cash equivalents
Trade and other receivables

Liabilities 
Trade and other payables

On demand 
Carrying and less than
3 months
amount
£
£

2,159,054
141,375

2,159,054
141,375

2,300,429

2,300,429

289,273

289,273

289,273

289,273

On demand 
Carrying and less than
3 months
amount
£
£

2,159,054
141,375

2,159,054
141,375

2,300,429

2,300,429

289,278

289,278

289,278

289,278

3 to 12
months 1 to 2 years
£

£

2 to 5 years 
£ 

–
–

–

–

–

–
–

–

–

–

– 
– 

– 

– 

– 

3 to 12
months 1 to 2 years
£

£

2 to 5 years 
£ 

–
–

–

–

–

–
–

–

–

–

– 
– 

– 

– 

– 

 
 
 
262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 50

50  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

17 Share capital 

Company – Issued and fully paid

As at 30 June 2019

As at 30 June 2020

Ordinary shares issued at 16p per share
Costs related to shares issued
Warrants issued at 9p per share

As at 30 June 2021

Number of  
shares

Share capital Share premium  
£ 

£

128,083,494

1,280,835

4,923,890 

128,083,494

1,280,835

4,923,890 

27,806,428

278,064

890,314

8,903

4,170,964 
(408,042) 
71,225 

156,780,236

1,567,802

8,758,037 

On 2 November 2020 27,806,428 ordinary shares were issued by way of a placing at a price of 16p per share to raise 
finance. 

On 19 March 2021 890,314 ordinary shares were issued in connection with the exercise of share warrants at an exercise 
price of 9p per share payable in cash. 

Share capital is the amount subscribed for shares at nominal value, issued and fully paid. 

Share premium is the amount subscribed for share capital in excess of nominal value. 

18 Share-based payments 
Share Options 
The Group operates share-based payment arrangements to remunerate directors and others providing similar services in 
the form of a share option scheme. The exercise price of the option is normally equal to the market price of an ordinary 
share in the Group at the date of grant. Each share option converts into one ordinary share of the Group on exercise. No 
amounts are paid or payable by the recipient on receipt of the option. The options carry neither rights to dividends nor 
voting rights. 

Movements in the number of share options outstanding and their related weighted average exercise prices are as follows: 

2021

2020 

Group and company

Outstanding at 1 July
Granted during the year
Forfeited/cancelled during the year

Number of
options

16,729,343
–
–

Weighted
average
exercise Number of
options

price
£

Weighted 
average 
exercise 
price 
£ 

0.11 14,919,648
1,809,695
–

–
–

0.11 
0.09 
– 

0.11 

Outstanding at 30 June

16,729,343

0.11 16,729,343

On 3 March 2020, 512,334 options were granted at an exercise price of £0.095 per share and are exercisable based upon 
achieving either of two market conditions. These market conditions are based on the signing of a joint development 
agreement between the Company and Winclove Probiotics B.V. or a qualifying exit with a share price of not less than 18p. 
The first condition has been met so the share options are exercisable immediately, although none have yet been exercised. 
The fair value of these share options have been estimated at cost as the share options are available immediately. The total 
charge recognised for the year ended 30 June 2021 for these share options is the entire fair value of £nil (2020: £48,672). 

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 51

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  51

On 8 April 2020, 1,297,361 options were granted at an exercise price of £0.09 per share and are exercisable based upon 
achieving one of three performance conditions. The performance conditions are based on the commercial viability of 
developed products, or the entering into of joint ventures, partnerships, collaborations or agreements for the sale or 
licensing of products. The total charge recognised for the year ended 30 June 2021 for these share options is £5,632 
(2020: £1,296). 

The fair values of the share options issued in the year were derived using the Black Scholes model. The total charge 
recognised for the year ended 30 June 2021 for share options is £61,257 (2020: £155,811). The following assumptions 
were used in the calculations: 

Deed pool
Grant date
Exercise price
Share price at grant date
Risk-free rate
Volatility
Expected life
Fair value

Deed pool
Grant date
Exercise price
Share price at grant date
Risk-free rate
Volatility
Expected life
Fair value

1
05/04/17
9p
9p
0.24%
60%
3.5 years
2.58p

4
18/04/19
18p
18p
0.75%
60%
3.5 years
2.85p

2
05/04/17
9p
9p
0.24%
60%
3.5 years
1.85p

5
18/04/19
18p
18p
0.75%
60%
3.5 years
3.99p

3a
05/04/17
9p
9p
0.16%
60%
2.75 years
2.30p

6
18/04/19
18p
18p
0.75%
60%
3.5 years
3.48p

3b
05/04/17
9p
9p
0.16%
60%
2.75 years
2.30p

7
03/03/20
9.5p
9.5p
0.29%
80%
0 years
9.50p

3c 
05/04/17 
9p 
9p 
0.16% 
60% 
2.75 years 
2.30p 

8 
08/04/20 
9p 
7p 
0.12% 
80% 
2 years 
0.87p 

The closing share price per share at 30 June 2021 was 63.50p (30 June 2020: 17.13p). 

Expected volatility is based on a conservative estimate for an AIM listed entity. The expected life used in the model has 
been  adjusted,  based  on  management’s  best  estimate,  for  the  effects  of  non-transferability,  exercise  restrictions  and 
behavioural considerations. 

19 Related party transactions 
Key management personnel compensation 

Group and company 
Short-term employee benefits including social security costs
Post-employment benefits
Share-based payments

2021
£

2020 
£ 

679,046
10,036
61,257

750,339

537,657 
4,072 
153,890 

695,619 

Compensation figures above include directors and key management personnel. Detailed remuneration disclosures for 
directors are provided in the employees and directors note on page 43, and in the Directors Report.  

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 52

52  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the Financial Statements (continued) 

For the Year Ended 30 June 2021

19 Related party transactions (continued) 
Transactions with other related parties 
During the period ended 30 June 2021, the Company was charged fees of £116,600 (2020: £101,652) by Quinn Corporate 
Services Ltd, a company in which Doug Quinn, a director of the Company, is also a director. These fees relate to Doug 
Quinn’s consultancy services to the Company. As at 30 June 2021 £9,500 (2020: £8,265) was outstanding. 

During the period ended 30 June 2021, the Company was charged fees of £58,000 (2020: £38,342) by Invictus Management 
Ltd, a company in which Martin Hunt, a director of the Company, is also a director. These fees relate to Martin Hunt’s 
consultancy services to the Company. As at 30 June 2021 £4,800 (2020: £4,800) was outstanding. 

During the period ended 30 June 2021, the Company was charged fees of £29,000 (2020: £22,400) by Biolatris Ltd, a 
company in which Dr Cathy Prescott, a director of the Company, is also a director. These fees relate to Dr Cathy Prescott’s 
consultancy services to the Company. As at 30 June 2021 £nil (2020: £nil) was outstanding. 

20 Ultimate controlling party 
No one shareholder has control of the Company. 

21 Events after the reporting date 
The Company has evaluated all events and transactions that occurred after 30 June 2021 up to the date of signing of the 
financial statements. 

No material subsequent events have occurred that would require adjustment to or disclosure in the financial statements. 

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 53

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  53

Notice of Annual General Meeting 

SKINBIOTHERAPEUTICS PLC (the “Company”) 
(Registered in England and Wales with company number 09632164) 

NOTICE IS HEREBY GIVEN THAT the Annual General Meeting of the above named Company will be held at The Core, 
Bath Lane, Newcastle Helix, Newcastle upon Tyne, NE4 5TF on 23 December 2021 at 11:00 AM for the transaction of the 
following business: 

Ordinary Resolutions 
To consider, and if thought fit, to pass the following resolutions 1 to 7 as ordinary resolutions: 

1.   THAT the Directors’ and Auditors’ reports and the financial statements for the financial year ended 30 June 2021 be 

received and adopted. 

2.   THAT Jeffreys Henry be re-appointed as the auditors of the Company until the next Annual General Meeting and the 

Directors be authorised to fix their remuneration. 

3.   THAT Stuart Ashman, be re-elected as a Director of the Company. 

4.   THAT Martin Hunt, be re-elected as a Director of the Company. 

5.   THAT Dr Cathy Prescott, be re-elected as a Director of the Company. 

6.   THAT Doug Quinn, be re-elected as a Director of the Company. 

7.   THAT in substitution for all existing authorities the Directors be given power under Section 551 of the Companies Act 
2006 (“the Act”) to exercise all the powers of the Company to allot shares in the Company and to grant rights to subscribe 
for, or to convert any security into, shares in the Company (“Rights”): 

      (i)

      (ii)

up to an aggregate nominal amount of £522,600.79 being equivalent to one-third of the Company’s issued share 
capital; and, 

up to a further aggregate nominal amount of £522,600.79 provided that (a) they are equity securities (within the 
meaning of section 560(1) of the Act) and (b) they are offered by way of a rights issue to holders of ordinary shares 
in the Company at such record dates as the directors may determine where the equity securities attributable to 
the interests of the ordinary shareholders are proportionate (as nearly as may be practicable) to the respective 
numbers  of  ordinary  shares  held  by  them  on  any  such  record  date,  subject  to  such  exclusions  or  other 
arrangements as the directors may deem necessary or expedient to deal with fractional entitlements or legal or 
practical problems arising under the laws of any overseas territory or the requirements of any regulatory body or 
stock exchange or any other matter whatsoever, provided that this authority shall, unless renewed, varied or revoked 
by the Company, expire twelve months after the date of passing of this Resolution or, if earlier, the date of the next 
AGM of the Company unless any offer or agreement is made before the end of that period in which case the 
Directors may allot shares and grant Rights pursuant to such offer or agreement as if the power granted by this 
resolution had not expired. 

Special Resolutions 
8.   THAT, subject to the passing of Resolution 7 and in accordance with Sections 570 and 573 of the Act, the Directors be 
and are hereby authorised to allot equity securities (as defined in section 560 of the Act) for cash under the authority 
conferred by Resolution 7and/or to sell ordinary shares held by the Company as treasury shares as if section 561 of the 
Act did not apply to any such allotment or sale, provided that such authority shall be limited to: 

      (i)

the allotment of equity securities in connection with rights issues, open offers or other pre-emptive offers in favour 
of holders of equity securities in proportion (as nearly as may be practicable) to their respective holdings or in 
accordance with the rights attaching thereto (but with such exclusions or other arrangements as the Directors may 
deem necessary or expedient to deal with fractional entitlements, record dates or other legal or practical problems 
in or under the laws of, or any requirements of, any recognised regulatory body or stock exchange, in any territory 
or as regards shares held by an approved depositary or in issue in uncertified form or otherwise however); and 

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 54

54  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notice of Annual General Meeting (continued) 

      (ii)

the allotment of equity securities or sale of treasury shares (otherwise than pursuant to sub-paragraph (i) above) 
to a maximum aggregate nominal value of £78,390.12; such power shall expire at the end of the next Annual 
General Meeting of the Company or 30 December 2022 (whichever is the sooner) unless any offer or agreement 
is made which would, or might require equity securities to be allotted (and treasury shares sold) before expiry of 
this power in which case the Directors may allot securities pursuant to such offer or agreement as if the power 
granted by this resolution had not expired. 

9.   THAT, subject to the passing of Resolution 7, and in addition to the power contained in Resolution 8 above, the Directors 
be and are hereby authorised, pursuant to sections 570 and 573 of the Act to allot equity securities (as defined in section 
560 of the Act) for cash, either under the authority conferred by Resolution 7 and/or to sell ordinary shares held by the 
Company as treasury shares as if section 561(1) of the Act did not apply to any such allotment or sale, provided that 
such authority shall be limited to: 

      (i)

the allotment of equity securities or sale of treasury shares, up to a maximum aggregate of £78,390.12; and 

      (ii)

used only for the purposes of financing (or refinancing, if the power is to be exercised within six months after the 
date of the original transaction) a transaction which the Directors determine to be an acquisition or other capital 
investment of a kind contemplated by the Statement of Principles on Disapplying Pre-Emption Rights published 
by the Pre-Emption Group prior to the date of this Notice of Annual General Meeting, such power shall expire at 
the end of the next Annual General Meeting of the Company or 30 December 2022 (whichever is the sooner) 
unless any offer or agreement is made which would, or might require equity securities to be allotted (and treasury 
shares sold) before expiry of this power in which case the Directors may allot securities pursuant to such offer or 
agreement as if the power granted by this resolution had not expired. 

By Order of the Board 

Doug Quinn
Company Secretary

Dated 30 November 2021

Registered Office 
15 Silk House 
Park Green Macclesfield 
England 
SK11 7QJ 

262369 SkinBio Therapeutics plc pp35-imp.qxp  29/11/2021  10:21  Page 55

SkinBioTherapeutics plc  Annual Report & Accounts 2021  |  55

Notes to the AGM notice

Resolution 1 – To receive the Annual Report and Financial Statements 
The Directors are required to present the financial statements, Directors’ Report and Auditor’s Report to the meeting. These 
are contained in the Company’s Annual Report for the year ended 30 June 2021 (the “Annual Report”). A resolution to 
receive the Annual Report is proposed as an ordinary resolution. 

Resolution 2 – Re-appointment and remuneration of Auditor 
At each meeting at which the Company’s financial statements are presented to its shareholders, the Company is required 
to appoint an auditor to serve until the next such meeting. The Board, on the recommendation of the Audit Committee, 
recommends  the  re-appointment  of  Jeffreys  Henry.  The  Resolution  also  authorises  the  directors  to  fix  the  auditor’s 
remuneration. 

Resolutions 3-6 – Re-election of Directors 
The Company’s Articles of Association require that any director that has not been re-elected at either of the preceding three 
annual general meetings shall retire and offer themselves for re-election by shareholders. Notwithstanding this requirement, 
the  Directors  have  determined  that  each  of  them  will  stand  for  re-election  on  an  annual  basis  in  accordance  with 
recommended best practice and in line with the principles of the UK Corporate Governance Code. 

Resolution 7 – Authority to allot shares 
The authority sought by this resolution is for the Directors to be authorised to allot Ordinary Shares up to two-thirds of the 
Company’s current issued share capital at the date of this notice. Paragraph (i) of the resolution will give the Directors a 
general  authority  to  allot  up  to  an  aggregate  nominal  value  of  £522,600.79  being  the  equivalent  of  one-third  of  the 
Company’s issued ordinary share capital at the date of this notice. This is in accordance with the Investment Association 
Share Capital Management Guidelines. In addition, the guidelines permit the authority to extend to a further third of the 
issued share capital, where any such shares allotted using this additional authority are in connection with a rights issue. 
Paragraph (ii) of the resolution proposes this additional authority be granted to the Directors. 

The Directors are seeking the annual renewal of this authority in accordance with best practice and to ensure the Company 
has maximum flexibility in managing its capital resources. The authorities in this Resolution will lapse at the conclusion of 
the next AGM or twelve months after the passing of the Resolution if earlier save for conditions set out in the Resolution. 

Resolutions 8 and 9 – Authority to disapply pre-emption rights 
Resolutions 8 and 9 are special resolutions which, if passed, will enable the Directors to allot shares in the Company, or to 
sell any shares out of treasury, for cash, without first offering those shares to existing shareholders in proportion to their 
existing shareholdings. In March 2015, the Pre-Emption Group published a revision of its Statement of Principles. In addition 
to restating the customary 5% limit on the issuance of shares for cash on a non-pre-emptive basis, the 2015 Statement of 
Principles introduced greater flexibility for companies to undertake non pre-emptive issues for cash in connection with 
acquisitions and specified capital investments. This relaxation allows companies the opportunity to finance expansion 
opportunities as and when they arise. The 2015 Statement of Principles provides that a company may now seek power to 
issue on a non-pre-emptive basis for cash equity securities representing: (i) no more than 5% of the Company’s issued 
ordinary share capital in any one year; and (ii) no more than an additional 5% of the Company’s issued ordinary share capital 
provided that such additional power is only used in connection with an acquisition of specified capital investment. In line 
with best practice, the Company has structured its pre-emption disapplication request as two separate resolutions. 

If Resolution 8 is passed, it will permit Directors to allot ordinary shares on a non-pre-emptive basis and for cash (otherwise 
than in connection with a rights issue or similar pre-emptive issue) up to a maximum nominal amount of £78,390.12. This 
amount represents 5% of the Company’s issued ordinary share capital as at 29 November 2021 (being the latest practicable 
date prior to publication of this document). This resolution will permit the Directors to allot any such shares for cash in any 
circumstances (whether or not in connection with an acquisition or specified capital investment). 

If Resolution 9 is passed, it will allow the Directors an additional power to allot ordinary shares on a non-pre-emptive basis 
and for cash up to a further maximum nominal amount of £78,390.12. This amount represents 5% of the Company’s issued 
ordinary share capital as at 29 November 2021 (being the latest practicable date prior to publication of this document). 

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56  |  SkinBioTherapeutics plc  Annual Report & Accounts 2021

Notes to the AGM notice (continued)

The Directors shall use any power conferred by Resolution 9 only in connection with an acquisition or specified capital 
investment which is announced contemporaneously with the issue, (or which has taken place in the preceding six-month 
period and is disclosed in the announcement at the time). 

1.     As stated above, members will not be entitled to attend the meeting. A member may not appoint a person other than the Chairman of the meeting as his 

proxy to attend and vote at the meeting. 

2.     In accordance with Regulation 41 of the Uncertificated Securities Regulations 2001 and by paragraph 18(c) of The Companies Act (Consequential 
Amendments) (Uncertificated Securities) Order 2009, only those members entered on the Company’s register of members not later than 11:00am on 
21 December 2021, or if the meeting is adjourned, Shareholders entered on the Company’s register of members not later than 2 days before the time 
fixed for the adjourned meeting (excluding non-business days) shall be entitled to vote at the meeting. 

3.     To be effective, the Form of Proxy must be deposited at the office of the Company’s registrars, Share Registrars Limited, Molex House, The Millennium 
Centre, Crosby Way, Farnham, Surrey, GU9 7XX so as to be received not later than 11:00am on 21 December 2021, or if the meeting is adjourned, not 
later than 48 hours (excluding non-business days) before the time fixed for the adjourned meeting. 

4.     CREST members who wish to appoint the Chairman as their proxy by utilising the CREST electronic proxy appointment service may do so for the meeting 
and any adjournment(s) thereof by utilising the procedures described in the CREST Manual. CREST Personal Members or other CREST sponsored members, 
and those CREST members who have appointed a voting service provider(s), should refer to their CREST sponsor or voting service provider(s), who will 
be able to take the appropriate action on their behalf. In order for a proxy appointment made by means of CREST to be valid, the appropriate CREST 
message (a ‘CREST Proxy Instruction’) must be properly authenticated in accordance with Euroclear UK & Ireland Limited’s specifications and must contain 
the information required for such instructions, as described in the CREST Manual. The message, regardless of whether it relates to the appointment of a 
proxy or to an amendment to the instruction given to a previously appointed proxy must, in order to be valid, be transmitted so as to be received by our 
agent Share Registrars Limited (ID 7RA36) no later than 11:00am on 21 December 2021 or, if the meeting is adjourned, 48 hours before the time fixed for 
the adjourned meeting (excluding any part of a day that is not a working day). For this purpose, the time of receipt will be taken to be the time (as 
determined by the timestamp applied to the message by the CREST Applications Host) from which the issuer’s agent, Share Registrars Limited, is able to 
retrieve the message by enquiry to CREST in the manner prescribed by CREST. After this time, any change of instructions to proxies appointed through 
CREST should be communicated to the appointee through other means. The Company may treat as invalid a CREST Proxy Instruction in the circumstances 
set out in Regulation 35(5)(a) of the Uncertificated Securities Regulations 2001. CREST members and, where applicable, their CREST sponsors or voting 
service providers should note that Euroclear UK & Ireland Limited does not make available special procedures in CREST for any particular messages. 
Normal system timings and limitations will therefore apply in relation to the input of CREST Proxy Instructions. It is the responsibility of the CREST member 
concerned to take (or, if the CREST member is a CREST personal member or sponsored member or has appointed a voting service provider(s), to procure 
that his CREST sponsor or voting service provider(s) take(s)) such action as shall be necessary to ensure that a message is transmitted by means of the 
CREST system by any particular time. In this connection, CREST members and, where applicable, their CREST sponsors or voting service providers 
arreeferred, in particular, to those sections of the CREST Manual concerning practical limitations of the CREST system and timings.     

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Contents

Statutory and Other Information

Chairman’s Statement

Strategic and Financial Review

Directors’ Report

Corporate Governance Report

Independent Auditor’s Report to the  
Members of SkinBioTherapeutics Plc

Consolidated Statement of Comprehensive  
Income

1 

2 

3 

10 

13 

23 

28 

Consolidated Statement of Financial Position

29 

Consolidated Statement of Cash Flows

30 

Consolidated Statement of Changes in Equity

31 

Company Statement of Financial Position

Company Statement of Cash Flows

Company Statement of Changes in Equity

Notes to the Financial Statements

Notice of Annual General Meeting

32 

33 

34 

35 

53 

Notes to the Annual General Meeting Notice

55 

Perivan    262369

262369 SkinBio Therapeutics plc Cover Spread (3mm Spine).qxp  29/11/2021  10:37  Page 1

Annual Report and Financial Statements 
For the Year Ended 30 June 2021

SkinBioTherapeutics plc 

Company Registration Number: 09632164

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SkinBio
THERAPEUTICS

15 Silk House, Park Green, Macclesfield, SK11 7QJ

SkinBio
THERAPEUTICS