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Verici Dx plc

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FY2021 Annual Report · Verici Dx plc
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Annual Report and Accounts
for the year ended 31 December 2021

Verici Dx plc

Annual report and financial statements
31 December 2021
for the year

ended

Contents 

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63 

Company Information 

Chairman’s statement 

Chief Executive Officer’s report 

Board of Directors 

Strategic report 

Directors' report 

Corporate governance statement 

Report of the remuneration committee 

Report of the audit of the financial statements 

Consolidated statement of profit or loss and other comprehensive income 

Consolidated statement of financial position 

Company statement of financial position 

Consolidated statement of cash flows 

Company statement of cash flows 

Consolidated statement of changes in equity 

Company statement of changes in equity 

Notes forming part of the consolidated financial statements 

Notice of Annual General Meeting 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Company information 
for the year ended 31 December 2021 

Directors 

Julian Baines, MBE (Non-Executive Chairman) 
Sara Barrington (Chief Executive Officer) 
Sir Ian Carruthers, OBE (Senior Independent Non-Executive Director) 
Dr Erik Lium (Non-Executive Director) 
James McCullough (Non-Executive Director)  
Dr Lorenzo Gallon (Non-Executive Director)  

Company Secretary 

Salim Hamir 

Registered Office 

Avon House 
19 Stanwell Road 
Penarth 
Cardiff, CF64 2EZ 

Company Number 

Registered in England and Wales Number 12567827 

Nominated Adviser 
and Broker 

Legal Adviser to the Company 

Auditors  

Registrar 

Registrar 

Financial PR 

Singer Advisory 
1 Bartholomew Lane 
London, EC2N 2AX 

BDB Pitmans LLP 
One Bartholomew Close 
London, EC1A 7BL 

Crowe U.K. LLP 
55 Ludgate Hill  
London EC4M 7JW 

Link Group 
The Registry 
34 Beckenham Road 
Beckenham 
Kent BR3 4TU 

Link Group 
The Registry  
34 Beckenham Road  
Beckenham  
Kent BR3 4TU 

Walbrook PR Limited 
75 King William Street  
London, EC4N 7BE 

Website 

 www.VericiDx.com 

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Verici Dx plc 

Chairman’s statement 
for the year ended 31 December 2021 

I am pleased to report on the twelve months ended 31 December 2021 for Verici Dx plc, representing the first full 
year of the Company being listed on AIM. 

2021  was  a  year  of  significant  progress  against  the  strategy  set  out  at  IPO  in  November  2020,  as  we  look  to 
commercialise our platform of innovative kidney transplant tests. Along with our two lead products, Clarava™ and 
Tuteva™, we are also developing a third related product, Protega™, resulting from a January 2021 expansion of our 
licence  agreement  with  Mount  Sinai.  Our  full  platform  of  tests  will  allow  us  to  offer  end-to-end  testing  for  kidney 
transplant  patients  and  their  clinicians,  enabling  us  to  improve  outcomes  for  patients  and  also  establish  a  strong 
competitive advantage. 

Our three products are:  

•  Clarava™, a pre-transplant prognosis test for the risk of early acute rejection; 
•  Tuteva™, a post-transplant test focused upon acute cellular rejection; and 
•  Protega™, a liquid biopsy that aims to predict the risk of fibrosis and long-term graft failure. 

There is an urgent clinical need in the kidney transplantation market. Globally, there are c. 300,000 people waiting 
for kidney transplants, with approximately c.100,000 transplants currently performed each year, of which c.24,000 
are performed in the US and 25,000 in Europe.  

During 2021, we completed all of our expected milestones either on time or ahead of schedule. We obtained a CLIA 
Certification of Registration from the Centers for Medicare & Medicaid Services (CMS) for our US clinical laboratory 
in Franklin, Tennessee, ahead of schedule, a significant commercial step at it allows Verici to initiate operations as 
a  diagnostic  laboratory.  We  were  also  granted,  ahead  of  schedule,  CPT®  Proprietary  Laboratory  Analyses 
codes for Clarava™ and Tuteva™ from the American Medical Association, which support the commercial use and 
tracking of these products within the US healthcare system. Critically, we completed the testing requirements of our 
multi-centre validation study for Clarava™ and Tuteva™ in December 2021, following a highly successful enrolment 
programme of partnering clinical sites and study participants over the course of the year; we exceeded our target 
numbers in both of these.  

During the year, we appointed Lorenzo Gallon, MD, as Non-Executive Director, and Chair of Science Advisory Board. 
An expert in nephrology and hypertension as well as organ transplantation, Dr Gallon is currently the Medical Director 
of  the  Translational  Medicine  Programme,  the  Director  of  International  Relations  and  the  Director  of  the  Renal 
Transplant Fellowship at Northwestern University. Dr Gallon’s appointment followed the sad and untimely passing of 
Dr Barbara Murphy, who was of course an integral part of the formation of Verici Dx, and whose legacy lives on in 
the work she inspired. 

Post-period end, Verici’s momentum has continued in the early stages of 2022. Significantly, we recently announced 
that the headline results of our international multi-centre validation study for Tuteva™ have shown a highly positive 
outcome, vindicating our decision to prolong the final close of the trial for Tuteva™ and Clarava™ to ensure greater 
numbers of qualified European patients were eligible for inclusion in the full study results. We believe this establishes 
a new industry standard in the detection of acute kidney transplant rejection, and positions Tuteva™ for commercial 
launch in the United States later this year. In January, we established a collaboration with Illumina, Inc. (NASDAQ: 
ILMN), a leading developer, manufacturer, and marketer of life science tools and integrated systems for large scale 
analysis of genetic variation and function, whereby Verici gained early access to the Illumina Connected Analytics 
(ICA) platform. In February, we also announced the major milestone of successfully completing analytical validation 
for Clarava™ and Tuteva™.  

We recently completed a Fundraise procuring a further £10m in gross proceeds, which will be used along with our 
existing resources, to advance towards key milestones for Protega™, and continue to push the commercialisation 
strategy for Clarava™ and Tuteva™, whilst carrying out planned improvements to the CLIA approved laboratory. 
These laboratory upgrades will accelerate capabilities ahead of marketing the Company's two leading products.  

2 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Chairman’s statement 
for the year ended 31 December 2021 (continued) 

We have been delighted with the progress of the Company in its first full year listed on AIM, and across the rest of 
2022 we look forward to the read-out of the key findings from our multi-centre validation study for Clarava™,  to 
further publications including the fuller implications of the Tuteva™ validation study and continuing to work towards 
the commercial launch of both lead products, as well as performing the necessary steps to efficiently validate our 
third product Protega™.  

On behalf of the Board, I would like to thank our employees, shareholders and partners for their support, and we look 
forward to providing further updates on progress throughout the rest of the year. 

Julian Baines 
Non-executive Chairman 
18 May 2022 

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Verici Dx plc 

Chief Executive Officer’s Report 
for the year ended 31 December 2021 

In our first full year as a listed Company, Verici Dx has made great progress, achieving all of our milestones either 
on or ahead of schedule.  

We  believe  we  have  unique  products  that  support  accurate,  data-driven  clinical  decisions,  such  as  the  most 
appropriate  immunosuppressive  therapy  for  that  patient.  This  has  not  only  near-term  scope  to  reduce  the 
unnecessary  and  serious  consequences  from  over-  or  under-dosing  for  immunosuppression  in  conjunction  with 
kidney transplant, but also to improve the longevity of transplanted kidneys and, by reducing the risk and rate of 
transplant failure, much broader potential to deliver huge health economic benefits by improving transplant outcomes. 

Our platform of innovative kidney transplant tests uses advanced next-generation sequencing that we believe can 
define a personalised risk profile for each patient.  

With the expansion of our product portfolio to cover fibrosis, we aim to address the patient’s entire transplant journey, 
from pre-transplant through to long-term risks, with a view to minimising the risk of transplant rejection.  

Pipeline 

Our two lead products, Clarava™ and Tuteva™, together with our third product Protega™ aim to understand how a 
patient will respond and is responding to a kidney transplant.  

The three products are underpinned by extensive patented and published scientific research from the leading Mount 
Sinai  Medical  Center,  for  which  the  Company  holds  an  exclusive  worldwide  licence.  Patient  enrolment  for  our 
collaborative, multi-centre observational clinical validation study, which we conducted alongside 14 leading US and 
EU medical centres in addition to Australia, was completed for Clarava™ and Tuteva™ in December 2021, in-line 
with expectations. 

We recently announced highly positive data from the validation study for Tuteva™, with the test having demonstrated 
a significantly higher Positive Predictive Value (“PPV”) than currently available blood tests, without enhancement 
from clinical features. Importantly, the validation study utilised generalised ‘all-comers’ patient population, rather than 
a specific subgroup. This means that we were able to test the power of Tuteva™ within a clinically realistic context 
that included all types of rejection, including sub-clinical, borderline, T Cell-mediated, and antibody-mediated rejection 
across  14  international  transplant  centres.  We  believe  that  the  highly  positive  results  reflect  the  wide  clinical 
applicability of the test for comprehensive commercial adoption in a real-world setting, and positions Tuteva™ for 
commercial launch in the US later this year. We expect to receive the read-out from the validation study for Clarava™ 
in the coming weeks. 

In  July  2021,  we  achieved  CLIA-certification  for  our  newly  established  laboratory  in  Tennessee,  a  key  step  in 
commercialising our two lead products, subject to the successful conclusion of our validation studies. 

Post-period end in January 2022, we were granted CPT® Proprietary Laboratory Analyses (“PLA”) codes for both 
Clarava™ and Tuteva™. Receiving these codes, ahead of schedule, marked the first step on the path for commercial 
reimbursement for our two lead products. Reimbursement in the US is comprised of three components: code, price 
and  coverage.  CPT®  codes  offer  health  care  professionals  a  uniform  language  for  coding  medical  services  and 
procedures  and  allows  clinical  laboratories  to  more  specifically  identify  their  tests  when  billing  Medicare  and 
commercial insurers.  

Partnerships and agreements 

In January 2021, we expanded the scope of our licence agreement with Mount Sinai to include an additional patent 
filing related to the analysis of gene expression in a liquid biopsy to predict risk of fibrosis and rejection of the graft. 
This led has led to the ongoing development of Protega™, which is currently undergoing patient enrolment for its 
validation, with enrolment expected to complete by Q3 2022 using the same site network already established for 
validation of our lead products. The end points of the Protega™ validation study are expected to be reached up to 
two years after the completion of enrolment, reflecting the longitudinal follow-up of patients over this period, with data 
expected shortly thereafter around year-end 2024. 

4 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Chief Executive Officer’s Report 

for the year ended 31 December 2021 

(continued)

In April 2021, the Company announced that it had entered into a Material Transfer Agreement with Mount Sinai and 
Principal Investigator Dr Peter Heeger, to allow access to de-identified samples generated from participants from the 
CTOT-19 study, in an effort to validate the performance and development of commercial tests designed to improve 
short and long-term graft and patient survival. 

Access to samples from this important clinical trial was initially intended to be included in the Company’s clinical 
validation studies for Clarava™ and Tuteva™, but the Company decided to keep study separate to provide Verici Dx 
with  a  further  large  and  well-characterised  sample  group  that  will  be  independently  reported.  The  Company’s 
laboratory  will  conduct  a  blinded  evaluation  of  samples  in  Clarava™  and  Tuteva™  and  work  with  investigators, 
including Dr. Peter Heeger, to characterise results after the Company’s validation study in 2022. 

Post-period end, we announced a collaboration with Illumina, Inc. to expedite the operational launch of data analysis 
processing  and  predictive  artificial  intelligence  component  of  our  products,  using  early  access  to  the  Illumina 
Connected  Analytics  (ICA)  platform.  Our  science  depends  on  the  ability  to  process  vast  amounts  of  data  into 
meaningful  and  interpretable  segments,  and  we  were  delighted  to  partner  with  such  a  world-class  provider  as 
Illumina, to help us do so. The partnership represented a key step in the readiness of both the near-term launches 
of Clarava™ and Tuteva™, as well as the longer-term strategy for building the computational data analytics tools 
that will power the future of Verici Dx’s data science and insights. 

Management and staff 

Currently, the Company employs 12 full time members of staff. 

In  November  2021,  we  launched  the  Barbara  T.  Murphy  Endowed  Lectureship  and  the  Career  Development 
Research Grant in conjunction with the American Society of Transplantation, in honour of our late co-founder and 
Board member, Dr Barbara Murphy. These two initiatives will help further the research base within the transplant and 
immunology fields, within which Barbara was a leading voice. 

Financials 

Statement of Comprehensive Income 

The  adjusted  EBITDA  being  the  loss  for  the  year,  before  the  deduction  of  interest,  taxation,  amortisation  and 
depreciation, and excluding the share-based payments charge and the costs of listing in 2020, was $7,151,244 (2020: 
$1,402,926).  This represents the first full year of activity, as the prior period’s activity occurred mainly following the 
admission to AIM on 3 November 2020.  The largest items of expenditure in this loss were staff costs of $1,961,622 
(2020: $258,852) and research and development costs of $2,809,435 (2020: $355,107).  We started the year with 3 
full time employees and ended the year with 10 full time employees. No employee costs are included in the research 
and development cost which relates to the development of our two core products in the year. 

Statement of Financial Position and Cash Flows 

Cash balance at year end was $10,339,788, following a total cash outflow in the year of $7,375,851 and a foreign 
exchange adjustment of $35,448 reducing the carrying value of cash balances at year end.  We spent $617,940 
(2020: $25,851) on tangible assets and $347,919 (2020: $132,259) on legal costs in the development of our patents 
and licenses. 

5 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Chief Executive Officer’s Report 

for the year ended 31 December 2021 

(continued)

Post-period  end  in  March  2022,  we  raised  £10.0m,  before  expenses,  via  a  Placing  and  a  Subscription.  The  net 
proceeds of the Fundraise will be used, together with the Company’s prior resources, to: 

•  Maintain  momentum  on  the  development  of  the  Company’s  third  product,  Protega™,  to  maximise  the 
efficiency gains in using existing validation sites set up for the Company’s two lead products, Clarava™ and 
Tuteva™; 

•  Carry out planned construction of the Company’s expanded CLIA approved laboratory facilities in Tennessee 

to support the scale-up of business operations in advance of commercialisation; 

•  Accelerate the commercialisation of lead products Clarava™ and Tuteva™ including through advocacy with 

clinicians; 

•  Explore  potential  growth  opportunities  including  adding  new  technology  (including  possible  in-licence  or 
acquisition) and Artificial Intelligence (“AI”) capability to support and enhance the use of Verici Dx product 
tests alongside digital histopathology imagery; 
•  Develop the Company’s nascent data assets; and 
•  Support general working capital purposes. 

Outlook 

We are well placed and funded to build on the excellent progress made over the course of 2021 and to continue the 
momentum established at the start of 2022 during the remainder of the year. By the end of 2022, we intend to have 
clearly moved from being a research and development Company to one with a commercial product. 

Following  the  March  2022  fundraise,  we  now  have  the  necessary  resources  to  not  only  commercialise  our  well-
differentiated core products, but also to progress the development of Protega™, as well as to find new exciting growth 
opportunities. Having already obtained CPT codes, we will seek to determine pricing for both of our lead products, 
and coverage determinations for Clarava™. Tuteva™ is expected to be eligible for and covered by an existing local 
coverage determination issued by Palmetto under the MolDX system.  

To support our commercialisation efforts, a health economics model is expected to be completed in the first half of 
2022.  We are also expected to engage in clinical utility and real-world evidence studies to support product adoption 
by the end of 2022. 

Sara Barrington 
Chief Executive Officer 
18 May 2022 

6 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Board of Directors 
for the year ended 31 December 2021 

The Directors of the Company during the period were: 

Julian Baines, MBE – Non-Executive Chairman 

Julian is the Company’s Non-Executive Chairman and member of the remuneration committee. 

Julian is the Deputy Non-Executive Chairman of EKF Diagnostics Holdings plc, previously CEO from 2009 to 2021. During 
his tenure at EKF, he has successfully completed multiple fundraisings and the acquisition and subsequent integration of 
eight businesses in seven countries, building revenue from zero to over £40,000,000. Prior to joining EKF, Julian was 
group chief executive officer of BBI Holdings plc, where he undertook a management buyout in 2000, its AIM flotation in 
2004  and  was  responsible  for  selling  the  business  to  Alere,  Inc.  (now  part  of  Abbott  Laboratories)  in  2008  for  c. 
£85,000,000. 

In 2016, Julian was awarded an MBE for services to the life sciences industry. Julian was appointed a Non-Executive 
Director of the Company on 22 April 2020. 

Sir  Ian  Carruthers,  OBE  –  Senior  Independent  Non-Executive  Director  and  chair  of  the  audit  committee  and 
nomination committee. 

Sir Ian Carruthers holds a number of chair and non-executive board and advisory roles in the public and private sectors. He 
was previously Chief Executive of NHS South of England, comprising three health bodies: South West, South Central and 
South East and his career in the National Health Service spans over 40 years. He was awarded the OBE for services to 
health in 1997 and a Knighthood in 2003 for services to the NHS.   In 2006 he took over as Interim Chief Executive of NHS 
England, amongst the largest organisations in the world with over 1.3 million employees and a budget in excess of £100 
billion. He has been the lead author on several papers on reviewing and improving the NHS and is seen as an international 
expert on healthcare systems and service delivery. 

He is currently Chancellor of the University of the West of England, and was formerly Chair of Healthcare UK, Chair 
of the Innovation Health and Wealth Implementation Board, Co-Chair of the Prime Minister’s Challenge on Dementia 
and Non-Executive Director of Bioquell plc. 

Sir Ian Carruthers was appointed as a Non-Executive Director of the Company on 19 August 2020. 

James  McCullough  –  Non-Executive  Director  and  member  of  the  remuneration  committee  and  the  nomination 
committee 

James is a Non-Executive Director and the CEO of Renalytix. 

James  has  experience  building  emerging  technology  companies  in  both  the  public  and  private  sectors  with  specific 
expertise  in  the  life-sciences  industry.  His  skills  include  equity  and  debt  capital  formation,  strategic  development  and 
partnerships, executive team structuring, regulatory issues and marketing. The Renalytix IPO was completed in November 
2018, raising over £22,000,000 for the company. Following successful progress in validatory development, regulatory 
discussions, reimbursement, pricing and insurance coverage determinations, a follow-on fundraise was arranged in July 
2019 at over double the IPO price, enabling expansion of the team and acceleration of key workstreams. In July 2020, 
Renalytix  successfully  dual-listed  on  Nasdaq  with  a  market  capitalisation  of  £378,130,000  after  raising  a  further 
$85,000,000 (approximately £68,000,000). 

7 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Board of Directors 
for the year ended 31 December 2021 (continued) 

James  McCullough  –  Non-Executive  Director  and  member  of  the  remuneration  committee  and  the  nomination 
committee (continued) 

Prior to his role at Renalytix, James was Chief Executive Officer of Exosome Diagnostics, a venture backed personalised 
medicine company developing non-invasive liquid biopsy diagnostics in cancer. Exosome Diagnostics was acquired by 
Bio-Techne  Corporation  (NASDAQ:  TECH)  in  2018.  James  is  also  a  managing  partner  of  Renwick  Capital,  LLC,  a 
management consulting firm specialising in assisting emerging healthcare technology companies with strategic planning 
and business execution. 

James  received  his  B.A.  from  Boston  University  and  an  M.B.A.  from  Columbia  Business  School.  James  is  currently 
Chairman of BalletNext, a performing arts company in New York City. He currently holds Series 79 and Series 63 securities 
licenses from the Financial Industry Regulatory Authority in the US. 

James was appointed a Non-Executive Director of the Company on 22 April 2020. 

Sara Barrington – Chief Executive Officer 

Sara is an Executive Director. 

Sara has leadership experience both financially and operationally with a focus upon developing and commercialising life 
science products. She was the CEO of LungLife AI a diagnostic company for early-stage lung cancer. Prior to that she 
was with Bruin Biometrics, a LA-based medical device company as EVP Business Operations and previously CFO. In her 
role at Exosome Diagnostics, a venture-backed personalised medicine company the focus was upon the development of 
non-invasive liquid biopsy diagnostics in cancer.  The company was successfully sold to Bio-Techne Corporation in 2018. 
She  was  previously  CFO  at  AusAm  Biotechnologies  developing  diagnostics  in  kidney  disease.  Sara  is  also  CCO  of 
Kantaro Biosciences, a joint venture between Renalytix and Mount Sinai for the commercialisation of COVID-19 antibody 
testing. Prior to working in the US, she worked for British Telecom in London in business development and strategy. 

Sara is qualified as a Chartered Accountant with the Institute of Chartered Accountants in England and Wales. She 
has also qualified with Chartered Institute of Marketing. 

Sara was appointed a Director of the Company on 19 August 2020. 

Dr. Erik Lium – Non-Executive Director and chair of the remuneration committee. 

Dr Lium in his capacity as Non-Executive Director will represent Mount Sinai on the Board as part of the ongoing 
relationship between the Company and Mount Sinai. 

Dr Lium is President of Mount Sinai Innovation Partners (MSIP) and Executive Vice President and Chief Commercial 
Innovation Officer, Mount Sinai Health System. He is also Non-Executive Director of Renalytix. Dr Lium represents Mount 
Sinai on several private company boards and previously served as a member of the investment review committee for the 
Accelerate NY Seed Fund. Dr Lium also serves as chairman of the board of managers of Kantaro. 

Prior to joining Mount Sinai, Dr. Lium served as the Assistant Vice Chancellor of Innovation, Technology & Alliances at the 
University of California, San Francisco (UCSF), and the UCSF Principal Investigator for the Bay area National Science 
Foundation I-Corps node and Assistant Vice Chancellor of. Dr. Lium served as President of LabVelocity Inc. prior to its 
acquisition in 2004. He pursued post-doctoral research at UCSF in the laboratory of J. Michael Bishop, MD, and earned a 
PhD with honours from the Integrated Program in Cellular, Molecular and Biophysical Studies at Columbia University in 
the laboratory of Dr. Saul J. Silverstein. Dr. Lium holds a BS in Biology from Gonzaga University. 

Dr Lium was appointed a Non-Executive Director of the Company on the 19 August 2020. 

8 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Board of Directors 
for the year ended 31 December 2021 (continued) 

Dr. Lorenzo Gallon – Non-Executive Director and member of the audit committee 

A Professor of Medicine (Nephrology and Hypertension) and Surgery (Organ Transplantation), Dr. Gallon is currently 
the Medical Director of the Translational Medicine Programme, the Director of International Relations and the Director 
of the Renal Transplant Fellowship at Northwestern University. He is an alumnus of the University of Padua Medical 
School, Italy and Harvard Medical School. 

An expert in nephrology and hypertension as well as organ transplantation, Dr. Gallon’s primary research interests 
include:  

•  The role of immunosuppressive medications in modulating the immune system,  
•  Genomics of chronic renal allograft rejection,  
•  Prednisone-free and calcineurin inhibitors-free immunosuppressive protocols, 
•  New immunosuppressive strategies, 
•  Focal segmental glomerulosclerosis (FSGS), and 
•  Aging and impact of physical exercise after kidney transplantation. 

With  nearly  20  years’  experience  in  the  life  sciences  industry,  focusing  largely  on  nephrology  and  organ 
transplantation, Dr. Gallon is excellently placed to provide insight and guidance in the development of Verici’s two 
lead products, Clarava™ and Tuteva™.  He was a collaborator and co-author with Verici’s previous SAB Chair, Dr. 
Barbara Murphy, in the GoCar study which was foundational in the development of Verici’s products. He has also 
been a member of the Editorial Board at the journal Nephron since 2019.  

9 

 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 

Our Strategy and Business Model 

Verici Dx plc is an immuno-diagnostics development company, initially focused on the kidney transplantation market. The 
Company’s kidney transplant assays use advanced next-generation sequencing that may define a personalised risk-profile 
of patients over the course of their transplant journey, as well as may detect injury in advance of currently available clinical 
tests. 

The Company successfully admitted trading on AIM, a market operated by the London Stock Exchange on 3 November 
2020 raising gross proceeds of US$18.8m.  In the period to 31 December 2020 the Company focussed on putting in place 
the additional people and resources to enable it to commence its clinical trials in 2021. 

Kidney transplantation is the treatment of choice for subjects with end stage renal disease (“ESRD”). An estimated 37 to 50 
per cent. of recipients have evidence of a rejection event which can be sub-divided into: 

•  Clinical Acute Rejection (“cAR”) occurring in approximately 10 per cent. to 15 per cent. of kidney transplant 
recipients in the first-year post-transplant. This is usually indicated by a rise in serum creatinine over baseline 
and determined by a for-cause biopsy. It is usually alleviated with a change in immunosuppressive therapy. 

•  Subclinical Acute Rejection (“subAR”) occurring in 27 to 40 per cent. of patients with stable serum creatine 
in the first 1-year post- transplant. It can be referred to as silent rejection because it often goes undetected. 
The only way to identify subAR is through a surveillance biopsy. However only 17 per cent. of transplant 
centres in the U.S. employ a surveillance biopsy program. 

It  is  now  well  established  that  the  recipient’s  immune  response  directed  toward  the  transplanted  kidney  drives  acute 
rejection, leading to chronic injury and failure of the transplant, thus necessitating lifelong immunosuppression drug therapy. 
One of the major issues with current immunosuppressive protocols is that they are not tailored to the individual patient’s 
needs. In clinical practice, immunosuppressive therapy is often decided based on broad clinical criteria including anti-HLA 
antibodies, race, prior transplantations and recipient age. However, these indicators perform poorly in predicting individual 
risk for development of acute rejection. As a result, most patients receive a standardised immunosuppressive protocol 
resulting  in  a significant proportion of  individuals  being  exposed  to  either  insufficient  or  excessive  immunosuppression, 
leading to acute rejection and/or complications associated with over-immunosuppression. These complications include 
infections,  malignancy,  diabetes,  hypertension  and  heart  disease.  The  number  of  patients  receiving  higher  doses  of 
immunosuppression around the time of a transplant continues to increase in an attempt to minimise rejection and protect 
the transplanted kidney.  

Current standard of care 

There is no current pre-transplant mechanism to determine the optimal approach to immunosuppressive therapy for a 
given patient beyond the presence of recipient antibodies directed toward the donor tissue, which can be found in only 
approx.  10  per  cent.  of  patients.  Early  identification  of  individuals  at  high  risk  of  acute  rejection  could  allow  targeted 
therapies aimed at improving long-term outcomes. Evidence exists that the phenotype and function of the immune system 
in  patients  before  kidney  transplantation  affects  the  risk  for  subsequent  acute  rejection  after  transplantation,  but  no 
biomarker has been identified to quantify or otherwise assess this risk. Following transplant, clinicians use a standardised 
approach to managing immunosuppression, slowly reducing drug levels to a maintenance level over the first three to six 
months.  There  are  currently  no  biomarkers  available  to  indicate  if  a  patient  is  under  or  over  immunosuppressed. 
Manifestation of clinical acute rejection via measurement of serum creatinine is the standard of care as well as tests that 
use cfDNA used to determine that a patient is experiencing rejection, which means measuring the damage to the kidney 
by observing the effects of the damage after it has happened increasing the risk of rejection. There is no generally accepted 
mechanism to identify patients with subclinical acute rejection, except to find evidence of rejection on a surveillance biopsy. 
Furthermore, there is no clinically available mechanism to identify a patient that is at risk of developing graft injury, either 
inflammation or fibrosis or both, and therefore at risk of long-term graft failure. 

10 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 (continued) 

Our Strategy and Business Model (continued) 

Verici’s proposed solution 

To address this “one size fits all approach” the Company is developing tests to understand how a patient is likely and may 
be responding to organ transplant. There are many biological systems that are important in assessing rejection. One is 
the recipient’s immune system which poses a threat to the grafted organ. Patients’ immune systems vary in their response 
to the presence of the transplanted organ. The Company’s products and solutions are underpinned by extensive scientific 
research into how the recipient’s biological systems are likely to respond to the transplanted organ and how that response 
further influences acute rejection, chronic injury and, ultimately, failure of the transplant. These RNA signatures may also 
assist  clinicians  as  to  their  assessment  of  the  optimal  strategy  for  immunosuppressive  and  other  therapies  to  enable 
successful graft acceptance at the lowest compatible level of treatment-induced side effects. 

The research underpinning our technology is driven by a deep understanding of cell-mediated immunity and is facilitated 
by access to expertly curated, collaborative studies in highly informative cohorts in organ transplant. The Company has an 
exclusive worldwide patent and a non-exclusive technical information licence with Mount Sinai derived from the work of 
the late Professor Barbara Murphy’s and collaborators in transplant immunology, focusing on the use of high throughput 
genomic  technologies  to  understand  better  the  immune  system  mechanisms  that  lead  to  graft  injury  and  loss.  The 
Company’s current and planned clinical development programmes are not only directed by an extensive Science Advisory 
Board of key opinion leaders in the fields of clinical transplant and transplant immunology, but also will be conducted at an 
expanding list of key transplant centres in the US, Europe and Australia for the multi-centre validation trials being funded. 

We are validating three products for commercialisation: 

•  ClaravaTM, which is a pre-transplant prognosis for the risk of early acute rejection (“EAR”); 

•  TutevaTM, a post-transplant diagnostic focused upon acute cellular rejection (“ACR”) including sub-clinical 
rejection not being diagnosed through the current standard of care of rising serum creatine levels; and 

•  ProtegaTM, a liquid biopsy that aims to predict the risk of fibrosis and long-term graft failure. 

These products are planned to be offered as laboratory developed tests (“LDT”) in the US, taking advantage of the lighter 
regulatory burden of authorisation under the CLIA regime, which is administered by CMS, in partnership with state health 
departments, rather than seeking clearance from the FDA. In Europe the company will be seeking CE marking. CE marking 
issued by an EEA Notified Body will remain valid in the UK market until 30 June 2023. To address the UK market post-Brexit, 
the Company will be seeking for UKCA (UK Conformity Assessed) mark as well. In addition to obtaining CE and UKCA 
markings, the products (medical devices) will be registered with MHRA (as required by MHRA since 1 January 2021).  

The Company is planning on complementing this commercial path with an efficient route through reimbursement coding, 
pricing and coverage determinations in the US. For inclusion into NICE guidelines in the UK, evidence-based data (such as 
health economic cost-effectiveness and patient outcome/clinical-effectiveness data, along with diagnostic test accuracy data), 
shall be applied for review by NICE Diagnostic Assessment Programme. 

Market opportunity 

Globally there are approximately 95,000 transplants currently performed each year of which about 24,000 are performed 
in the US and 25,000 in Europe. In the US the comparatively low number of procedures compared to the numbers of 
individuals on the waiting list was recognised as an issue for patients waiting for a transplant for on average 3 to 5 years, 
and  even  longer  in  some  geographical  locations.  It  also  formed  part  of  the  policy  in  the  2019  US  Executive  Order, 
Advancing  American  Kidney  Health  whereby  transplant  organisations  were  required  to  improve  efficiencies  in  the 
transplant  network  and  expand  support  for  living  donors  with  the  further  goal  of  doubling  the  number  of  available 
transplants by 2030.  The Company’s portfolio is likely to support the confidence for living donors from the increased 
success of transplantation. 

11 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 (continued) 

Group and Company History 

The Company was incorporated in England and Wales on 22 April 2020 as a wholly owned subsidiary of Renalytix 
AI plc (“Renalytix”). 

On 4 May 2020 the Company purchased the assets attached to the Fractal DX portfolio of patents previously licensed to 
Renalytix by Mount Sinai, for a consideration of $2,000,000. The consideration was satisfied by the issuance of a non-
interest-bearing Convertible Loan Notes (“CLNs”) from the Company to Renalytix. The CLN instrument provided for a 
total of up to $3,000,000 of borrowing to be made available to the Company. 

On 17 January 2020, ResolveDx Inc was incorporated in the state of Delaware, USA as a wholly owned subsidiary 
of Renalytix. On 14 August 2020, ownership of ResolveDx Inc was transferred to the Company and, on 21 August 
2020 ResolveDx Inc changed its name to Verici Dx Inc. 

Pursuant to the terms of the CLN’s, notice was given by Renalytix on 28 October 2020 to convert all of its existing 
debt of $2,500,000 by the Company into 9,831,681 ordinary shares of £0.001 each at the IPO issue price. 

In anticipation of a distribution in specie by Renalytix of its entire shareholding in the Company on 7 July 2020 the 
entire  issued  share  capital  of  the  Company  was  sub  divided  to  create  1,000  ordinary  shares  of  £0.001  each.  
Additionally,  59,415,135  ordinary  shares  of  £0.001  each  were  allotted.    Those  59,416,135  shares  were  then 
immediately reclassified as 59,416,134 A shares and 1 Golden Share and all the A shares and Golden Share were 
converted into new ordinary shares at the time of the Company’s admission to AIM, a market operated by the London 
Stock Exchange, on 3 November 2020. 

Risks and uncertainties 

Set out below are the risks which the Directors believe could materially affect the Group’s ability to achieve its financial 
and operating objectives and control or mitigating activities adopted to manage them. The risks are not listed in order 
of significance. 

(a)  The Company does not yet have all collaborations in place with institutions that it needs for its validation 
and for utility studies and there is no guarantee that the Company will be able to demonstrate clinical 
utility of the ClaravaTM  or TutevaTM product 

Following the validation study for its products, the Company intends to run a clinical utility study to support applications for 
reimbursement, which is necessary for successful commercialisation and to provide further evidence to support marketing 
claims. 

The Company has identified some initial institutions which will carry out the utility studies and has not yet entered into the 
relevant agreements with these institutions. There is a risk that the Company will not be able to secure these collaborations, 
which would impact the Company’s ability to proceed to the utility study stage. Whilst the utility study is not a source of 
continuing revenue, it is a short-term revenue stream from sales of the ClaravaTM and TutevaTM tests following the validation 
study. 

Furthermore,  there  is  a risk  that  the  Company  will  not  be  able  to  demonstrate  the  clinical  utility  of  the  ClaravaTM  and 
TutevaTM products in a real-world setting, which would impact the Company’s ability to secure reimbursement. If such 
reimbursement  is  not  achieved,  it  will  make  commercialisation  of  the  ClaravaTM  and  TutevaTM  tests  significantly  more 
challenging and would impact the Company’s ability to generate revenue. 

12 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 (continued) 

Risks and uncertainties (continued) 

(b)  There are risks associated with offering the ClaravaTM and TutevaTM tests as an LDT that are outside the 

Company’s control 

The ClaravaTM and TutevaTM tests do not as yet have status as an LDT and the Company does not yet have a CLIA-certified 
laboratory.  The  Company  may  be  able  to  generate  revenue  from  offering  the  ClaravaTM  and  TutevaTM  tests  as  an  LDT. 
However, there are inherent risks associated with offering the ClaravaTM and TutevaTM tests as an LDT that are outside the 
Company’s control, including test uptake, which would have an impact on the amount of revenue the Company could generate 

(c)  The  Company  is  dependent  on  other  third  parties  who  provide  certain  resources  and  services  to  the 

Company as the Company has limited resources in the short-term 

The Company relies in part on external resources to conduct the research, development, supply of supplies and clinical 
testing  of  its  ClaravaTM  and  TutevaTM  products,  including  in  relation  to  the  Company’s  laboratory  systems  which  rely  on 
software developed by external manufacturers. The future development  of  the  ClaravaTM  and  TutevaTM  products  and 
other products will partly depend upon the performance of these third parties. The Company cannot guarantee that 
the relevant third parties will be able to carry out their obligations under the relevant arrangements. 

(d)  The Company is reliant upon the expertise and continued service of a small number of key individuals 

of its management, board of directors and scientific advisors 

The Company relies on the expertise and experience of a small number of key individuals.  The retention of their services 
cannot be guaranteed. Accordingly, the departure of these key individuals could have a negative impact on the Company’s 
operations, financial conditions, its ability to execute the Company’s business strategy and future prospects. 

Going forwards, the Company will rely, in part, on the recruitment of appropriately qualified personnel, including personnel 
with a high level of scientific and technical expertise in the industry. The Company may be unable to find a sufficient number 
of appropriately highly trained individuals to satisfy its growth rate which could affects its ability to develop products as 
planned. 

In addition, if the Company fails to succeed in pre-clinical or clinical studies, it may make it more challenging to recruit and 
retain appropriately qualified personnel. The Company’s inability to recruit key personnel or the loss of the services of key 
personnel or consultants may impede the progress of the Company’s research and development objectives as well as the 
commercialisation of its lead and other products. 

(e)  The Company may need to raise additional funding to take advantage of future opportunities 

The Company may need to raise additional funding to take advantage of future opportunities. No assurance can be 
given that any such additional funding will be available or, if available, that it will be on terms that are favourable to 
the Company or shareholders. If the Company is unable to obtain additional funding as required, it may be required 
to reduce the scope of its operations or anticipated expansion. 

(f)  The Company’s strategy involves generating additional commercially valuable IP that can be protected 

The Company intends to build further its intellectual property portfolio. No assurance can be given that any future patent 
applications  will  result  in  granted  patents,  that  the  scope  of  any  patent  protection  will  exclude  competitors  or  provide 
competitive advantages to the Company, that any of the Company’s patents will be held valid if challenged or that third 
parties will not claim rights in or ownership of the patents and other proprietary rights held by the Company. 

13 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 (continued) 

Risks and uncertainties (continued) 

(g)  Positive results from pilot trials and early clinical studies of the Company’s ClaravaTM and TutevaTM products are 
not necessarily predictive of the results of later clinical studies. If the Company cannot replicate the positive 
results from earlier tests or studies in its later-stage clinical studies, it may be unable to successfully develop, 
obtain regulatory approval for, and commercialise its products 

Positive results from early stage clinical studies may not necessarily be predictive of the results from later-stage clinical 
studies. Many companies in the pharmaceutical biotechnology and medical device industries have suffered significant 
setbacks in later-stage clinical trials after achieving positive results in early-stage development, and the Company cannot 
be certain that it will not face similar setbacks. These setbacks have been caused, among other things, by pre-clinical 
findings made while clinical trials were underway. Moreover, pre-clinical and clinical data is often susceptible to varying 
interpretations and analyses, and many companies that believed their product candidates performed satisfactorily in pre-
clinical studies and clinical trials nonetheless failed to obtain regulatory approval. 

(h)  The Company is subject to research and product development risk 

The Company may not be able to develop new products or to identify specific market needs that can be addressed by 
tests  or  solutions  developed  by  the  Company.  Product  development  will  be  a  key  ongoing  activity  in  the  Company. 
However, there can be no guarantee that further products will be developed, successfully launched, or accepted by the 
market. All new product development has an inherent level of risk and can be a lengthy process and suffer unforeseen 
delays, cost overruns and setbacks, such as difficultly recruiting patients into clinical trials. The nature of the diagnostics 
industry may mean new products may become obsolete as a result of competition or regulatory changes which could 
have a material adverse effect on the Company’s business, results of operations and financial condition. 

In addition, research and development may subject to various requirements, such as research subject protection for 
individuals  participating  in  clinical  evaluations  of  new  products,  institutional  review  board  oversight,  regulatory 
authorisations, and design control requirements. Failure to comply with requirements could result in penalties, delay, or 
prevent commercialisation of products. 

(i)  The Company is subject to risks associated with medical and technological change and obsolescence 

Demand  for  the  Company’s  products  could  be  adversely  impacted  by  the  development  of  alternative  technology  and 
alternative medicines with similar applications. There can be no assurance that the technology and products currently 
being developed by the Company will not be rendered obsolete. As a result, there is the possibility that new technology or 
products may be superior to, or render obsolete, the technology and products that the Company is currently developing. 
Any failure of the Company to ensure that its products remain up to date with the latest advances may have a material 
adverse impact on the Company’s competitiveness and financial performance. The Company’s success will depend, in 
part, on its ability to develop and adapt to these technological changes and industry trends. 

(j)  The Company’s failure to maintain compliance of its clinical laboratory operations with applicable laws could 

result in substantial civil or criminal penalties 

The operation of a clinical laboratory by the Company will be in a highly regulated environment which, among other things, 
will require maintaining compliance with CLIA certification and state clinical laboratory licensing requirements. Failure to 
maintain compliance with these requirements may result in a range of enforcement actions, including certificate or licence 
suspension,  limitation,  or  revocation,  directed  plan  of  action,  onsite  monitoring,  civil  monetary  penalties  and  criminal 
sanctions. Such failure may also result in significant adverse publicity. Any of these consequences could limit or entirely 
prevent continued operation of the Company and therefore impact its financial performance. 

14 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 (continued) 

Risks and uncertainties (continued) 

(k)  The  Company  is  subject  to  various  health  regulatory  laws  pertaining  to  fraud  and  abuse  and  related 
matters, and any failure to comply with such laws could result in substantial civil or criminal penalties 

The Company’s employees, independent contractors, consultants, and collaborators may engage in misconduct or 
other improper activities, including non-compliance with regulatory standards and requirements, which could cause 
significant liability for the Company and harm the Company’s operations and reputation. 

The  Company  is  exposed  to  the  risk  that  the  Company’s  employees,  independent  contractors,  consultants,  and 
collaborators  may  engage  in  fraud  or  other  misconduct  to  comply  with  manufacturing  standards  the  Company  has 
established,  to  comply  with  federal  and  state  healthcare  fraud  and  abuse  laws  and  regulations  and  similar  laws  and 
regulations established and enforced by comparable non-US regulatory authorities, to report financial information or data 
accurately or to disclose unauthorised activities to the Company. Such misconduct could also involve the improper use of 
information obtained in the course of clinical trials, which could result in regulatory sanctions and serious harm to the 
Company’s reputation. It is not always possible to identify and deter misconduct, and the precautions the Company will 
take to detect and prevent this activity may not be effective in controlling unknown or unmanaged risks or losses or in 
protecting the Company from governmental investigations or other actions or lawsuits stemming from a failure to comply 
with such laws, standards or regulations. If any such actions are instituted against the Company, or the Company’s key 
employees, independent contractors, consultants, or collaborators, and the Company is not successful in defending itself 
or asserting the Company’s rights, those actions could have a significant impact on the Company’s business and results 
of  operations,  including  the  imposition  of  significant  criminal,  civil  and  administrative  sanctions  including  monetary 
penalties, damages, fines, disgorgement, individual imprisonment, additional reporting requirements and oversight if the 
Company  becomes  subject  to  a  corporate  integrity  agreement  or  similar  agreement  to  resolve  allegations  of  non-
compliance with these laws, reputational harm, and the Company may be required to curtail or restructure the Company’s 
operations. 

(l)  The Company’s failure to prevent a data breach would result in serious reputational damage to the Company and 

may result in civil or criminal lawsuits and associated penalties 

The Company takes its responsibility to maintain patient confidentiality and protect patient data extremely seriously. By its 
nature, the de-identified data that is being processed is highly sensitive and includes genetic and demographic information, 
the processing of which is subject to the most onerous obligations of applicable data protection legislation. If, due to a 
technical oversight, human error or malicious action by an employee or third party, the privacy, security or integrity of the 
data were compromised, the Company may be obliged to report such breach once it became aware of under applicable 
laws  and  regulations  such  as  Health  Insurance  Portability  and  Accountability  Act  1996  (“HIPAA”),  EU  General  Data 
Protection Regulation (EU) 2016/679 (“GDPR”), Data Protection Act 2018 (“DPA”) or other US state or EU member state 
specific laws as well as the data privacy laws of other countries such as Japan, Singapore, Hong Kong and China. 

Depending on the nature and extent of the breach, the Company may become subject to a regulatory investigation, which 
would divert time and financial resources from the day-to-day operation of the business and may result in civil or criminal 
lawsuits and financial fines and penalties as well as adverse publicity. If third parties and/or customers of the Company 
become aware of such breaches, they may opt to cancel existing contracts or not enter new contracts with the Company, 
reducing  revenue.  The  Company  may  also  be  required  to  personally  inform  the  patients  whose  data  was  released  or 
accessed as a result of a data breach, which may increase the severity of the reputational damage and may lead to patients 
revoking their consent for the data to be used by the Company. In addition, patients may have the right to bring claims for 
compensation for such breaches which might be brought by way of class or representative actions and claim significant 
sums  as  damages.  To  mitigate  the  risk  of  a  data  breach  or  related  issue,  the  Company  will  employ  technical  security 
measures to protect data and work closely with its data providers to ensure that each party understands its obligations to 
protect personal data. 

15 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Strategic report  
for the year ended 31 December 2021 (continued) 

Section 172 Statement 

The Directors, in line with their duties under s172 of the Companies Act 2006, act in a way they consider, in good 
faith, would be most likely to promote the success of the Company for the benefit of its members as a whole, and in 
doing so have regard to a range of matters when making decisions for the long term. Key decisions and matters that 
are of strategic importance to the Company are appropriately informed by s172 factors. 

Section 172(1)(a) to (f) requires each Director to act in the way he or she considers would be most likely to promote 
the success of the company for the benefit of its members as a whole, with regard to the following matters: 

(a)  the likely consequences of any decision in the long term 

(b)  the interests of the Company’s employees 

(c)  the need to foster the Company’s business relationships with suppliers, customers and others.  

(d)  the impact of the Company’s operations on the community and the environment 

(e)  the desirability of the Company maintaining a reputation for high standards of business conduct; and 

(f) 

the need to act fairly between members of the Company. 

The Company’s activities and progress regarding these matters have been described above in the other sections of 
the  Chief  Executive  Officer’s  Report,  Strategic  Report,  and  in  the  Directors’  Report  and  Corporate  Governance 
Statements below.   

This report was approved by the Board of Directors on 18 May 2022 and signed on its behalf by: 

Julian Baines 
Non-executive Chairman 

16 

 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Directors' report  
for the year ended 31 December 2021 

The Directors present their report on the affairs of Verici  Dx plc (the "Company") and its subsidiary, referred  to as the 
Group,  together  with  the  audited  Financial  Statements  and Independent  Auditors’  Report  for the  year  ended  31 
December 2021. 

Principal activities 

The main activity of the Group is the development of a prognostic and diagnostic test for kidney transplant patients. 

Results and dividends 

During the year ended 31 December 2021 the Group recorded a loss after tax of US$8,329,829 and a net cash outflow 
from operating activities of US$6,336,444. 

The Directors do not recommend the payment of a dividend. 

Going concern 

The Group is in the development phase of its business and has not generated any revenues. At 31 December 2021 
the Group has available cash resources of US$10,339,788. 

In considering the appropriateness of this basis of preparation, the Directors have reviewed the Company and Group 
working capital forecasts for a minimum of 12 months from the date of the approval of this financial information. Based 
on their consideration the Directors have reasonable expectation that the Group has adequate resources to continue 
for the foreseeable future and that carrying values of intangible assets are supported. Thus, the adoption of the going 
concern basis of accounting in preparing this financial  information is considered appropriate. 

Political donations 

The Group made no political donations in the period. 

Future developments 

The Group’s future developments are outlined in the Strategic Report on pages 10 to 16.  

Financial risk management 

Financial  risk  management  policies  and  objectives  for  capital  management  are  outlined  in  the  principal  risks  and 
uncertainties section of the Strategic Report on pages 10 to 16 and in note 4 to the financial statements. 

Directors’ indemnities 

The  Group  has  made  qualifying  third-party  indemnity  provisions  for  the  benefit  of  its  Directors,  which  were  made 
during the period and remain in force at the date of this report. 

Events after the reporting period 

Details of significant events since the reporting period are contained in note 22 of the financial statements. 

17 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Directors' report  
for the year ended 31 December 2021 (continued) 

Directors 

The Directors of the company throughout the year and to the date of this report were: 

Julian Baines MBE (appointed 22 April 2020) 
Sir Ian Carruthers OBE (appointed 19 August 2020) 
James McCullough (appointed 22 April 2020) 
Sara Barrington (appointed 19 August 2020) 
Dr Erik Lium (appointed 19 August 2020) 
Dr Barbara Murphy (appointed 22 April 2020, deceased 29 June 2021) 
Dr Lorenzo Gallon (appointed 18 August 2021) 

Directors’ shareholdings 

The holdings in the share capital of the Company of those Directors serving at 31 December 2021 and as at the date 
of signing of these financial statement, all of which are beneficial, were as follows: 

Julian Baines 
Sir Ian Carruthers 
James McCullough 
Sara Barrington 
Dr Erik Lium 
Dr Lorenzo Gallon 

On 31 December 2021 
Ordinary Shares of £0.001 each 
1,351,713 
100,000 
2,870,110 
- 
- 
- 

All of the shares were acquired at the time on IPO on 3 November 2020. 

Substantial shareholdings 

As of 14 April 2022, the following interests in 3% or more of the issued Ordinary Share capital, after taking account 
of the issue of new shares post year end pursuant to the funding, had been notified to the Company: 

Shareholder 
Harwood Capital 
Icahn School of Medicine at Mount Sinai 
Renalytix plc 
EKF Diagnostics Holdings Plc 
Unicorn Asset Management Limited 
Hargreaves Lansdown Asset Management 

Number of shares 
29,769,111 
19,501,330 
9,831,681 
9,820,838 
9,239,660 
6,094,357 

Percentage of issued 
share capital 
17.5% 
11.4% 
5.8% 
5.8% 
5.4% 
3.6% 

Christopher Mills is partner and Chief Investment Officer of Harwood Capital LLP.  Harwood Capital LLP is Investment 
Manager  to  North  Atlantic  Smaller  Companies  Investment  Trust  plc  and  investment  advisor  to  Oryx  International 
Growth  Fund  Limited.    Christopher  Mills’  shareholding  is  made  up  of  16,500,000  ordinary  shares  held  by  North 
Atlantic Smaller Companies Investment Trust plc, 5,500,000 ordinary shares held by Oryx International Growth Fund 
Limited and 1,722,501 ordinary shares are held by Harwood Capital LLP. 

18 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Directors' report  
for the year ended 31 December 2021 (continued) 

Corporate Social Responsibility 

The Board recognises its employment, environmental and health and safety responsibilities. It devotes appropriate 
resources  towards  monitoring  and  improving  compliance  with  existing  standards.  The  Executive  Directors  are 
responsible for these areas at Board level, ensuring that the Group’s policies are upheld and providing the necessary 
resources.  

The Directors consider that the nature of the Group’s activities is not inherently detrimental to the environment. The 
Group  is  committed to  identifying  and  minimising  any  effect  on  the  environment caused by its  operations  and  the 
Board recognises that the Group has  a duty to be a good corporate citizen and to respect and comply with the laws, 
regulations, and where appropriate the customs and culture of the territories in which it operates. 

Employees 

The Group is committed to achieving equal opportunities and to complying with relevant anti-discrimination legislation. 
It is established Group policy to offer employees and job applicants the opportunity to benefit from fair employment, 
without regard to their sex, sexual orientation, marital status, race, religion or belief, age or disability. Employees are 
encouraged to train and develop their careers. 

The Group has continued its policy of informing all employees of matters of concern to them as employees, both in 
their immediate work situation and in the wider context of the Group's well-being. Communication with employees is 
affected through the Board, the Group’s management briefings structure, formal and informal meetings and through 
the Group’s information  systems. 

Directors Responsibilities 

The Directors are responsible for preparing the Strategic Report, the Directors’ Report and the Financial Statements 
in accordance with applicable law and regulations. 

Company  law  requires  the  directors  to  prepare  financial  statements  for  each  financial  year.  Under  that  law  the 
directors  have  elected  to  prepare  the  financial  statements  in  accordance  with  International  Financial  Reporting 
Standards adopted in the UK (UK IFRSs’) and applicable law. 

Under company law the Directors must not approve the financial statements unless they are satisfied that they give 
a true and fair view of the state of affairs of the Company and the Group and of the profit or loss of the Group for that 
period. In preparing these financial statements, the Directors are required to: 

•  Select suitable accounting policies and then apply them  consistently 

•  Make judgements and accounting estimates that are reasonable and prudent 

•  State whether applicable accounting standards have been followed, subject to any material departures disclosed 

and explained in the financial statements;  and 

•  Prepare  ’the  financial  statements  on  the  going  concern  basis  unless  it  is  inappropriate  to  presume  that  the 

Company and Group will continue in  business. 

The Directors are responsible for keeping adequate accounting records that are sufficient to show and explain the 
Company’s transactions and disclose with reasonable accuracy at any time the financial position of the Company 
and  enable  them  to  ensure  that  the  financial  statements  comply  with  the  Companies  Act  2006.  They  are  also 
responsible for safeguarding the assets of the Group and the Company and hence for taking reasonable steps for 
the prevention and detection of fraud and other irregularities. 

19 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Directors' report  
for the year ended 31 December 2021 (continued) 

Directors Responsibilities (continued) 

They are further responsible for ensuring that the Strategic Report and the Directors’ Report and other information 
included in the Annual Report and Financial Statements is prepared in accordance with applicable law in the United 
Kingdom. 

The maintenance and integrity of the Verici Dx plc website is the responsibility of the directors. Legislation in the 
United Kingdom governing the preparation and dissemination of the accounts and the other information included in 
annual reports may differ from legislation in other jurisdictions. 

Auditors 

Each of the persons who are directors at the time when this Directors’ report is approved has confirmed that: 

• 

• 

so far as that Director is aware, there is no relevant audit information of which the Group and the Group’s auditor 
is unaware;  and 
that Director has taken all the steps that ought to have been taken as a Director in order to be aware of any 
relevant audit information and to establish that the Company and the Group’s auditor is aware of that information. 

Crowe U.K. LLP has expressed its willingness to continue in office and a resolution to reappoint the firm as Auditor 
and authorising the Directors to set their remuneration will be proposed at the forthcoming Annual General Meeting 

This report was approved by the Board of Directors on 18 May 2022 and signed on its behalf by: 

Julian Baines 
Non-executive Chairman 

20 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Corporate governance statement  
for the year ended 31 December 2021 

Compliance 

The  Company  recognises  the  value  of  good  corporate  governance  in  every  part  of  its  business.  The  Board  has 
adopted the corporate governance principles of the 2018 Quoted Companies Governance Code. Details of the Code 
can be obtained from the Quoted Companies Alliance’s website (www.theqca.com). 

The following statement describes how the Group seeks to address the principles underlying the Code. 

Board composition and responsibility 

The Board currently comprises one Executive Director and five Non-Executive Directors. Julian Baines has been 
appointed as Non-Executive Chairman. 

It is the Board’s opinion that Julian Baines, Sir Ian Carruthers, James McCullough, Dr Erik Lium, and Dr Barbara 
Murphy  are  independent  in  character  and  judgement  and  that  there  are  no  relationships  or  circumstances  which 
could materially affect or interfere with the exercise of their independent judgement. 

All Directors are subject to election by Shareholders at the first Annual General Meeting after their appointment and 
are subject to re-election at least every three years. Non-Executive Directors are appointed for a specific term of 
office which provides for their removal in certain circumstances, including under section 168 of the Companies Act 
2006.  The  Board  does  not  automatically  re-nominate  Non-Executive  Directors  for  election  by  Shareholders.  The 
terms of appointment of the Non-Executive Directors can be obtained by request to the Company Secretary. 

The Board’s primary objective is to focus on adding value to the assets of the Group by identifying and assessing 
business opportunities and ensuring that potential risks are identified, monitored and controlled. Matters reserved for 
Board  decisions  include  strategic  long-term  objectives  and  capital  structure  of  major  transactions.  The 
implementation of Board decisions and day to day operations of the Group are delegated to Management. 

There is a division of responsibilities between the Non-Executive Chairman, who is responsible for the overall strategy 
of the Group and running the Board, and the CEO, who is responsible for implementing the strategy and day to day 
running of the Group.  

Board meetings 

Three Board meetings were held during the period. The Directors’ attendance record during their period of office was 
as follows: 

Board  
(5 meetings held) 

Audit Committee 
(2 meetings held) 

5/5 
Julian Baines 
5/5 
Sara Barrington 
Sir Ian Carruthers 
5/5 
James McCullough  4/5 
Dr Erik Lium 
5/5 
Dr Barbara Murphy  1/2 
2/2 
Dr Lorenzo Gallon 

N/A 
N/A 
2/2 
N/A 
N/A 
0/1 
1/1 

Remuneration 
Committee 
(No meetings held)  
Nil 
N/A 
N/A 
Nil 
Nil 
N/A 
N/A 

During the year, the Board has not performed an evaluation of their performance and that of the Chairman, as well 
as the effectiveness of the Board committees.   

21 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Corporate governance statement  
for the year ended 31 December 2021 (continued) 

Audit Committee 

The Audit Committee comprises Sir Ian Carruthers, who acts as chair, and Dr Lorenzo Gallon The Audit Committee 
will, among other things, determine and examine matters relating to the financial affairs of the Company including 
the terms of the engagement of the Company’s auditors and, in consultation with the auditors, the scope of the audit. 
It will receive and review the reports from management and the Company’s auditors relating to the half yearly and 
annual accounts and the accounting and the internal control systems in use throughout the Company. 

The committee has met twice during the year ended 31 December 2021. There have been no significant matters 
communicated to the Committee by the auditors and no interaction with the Financial Reporting Council. 

Remuneration Committee 

The Remuneration Committee comprises Dr Erik Lium, who acts as chair, and Julian Baines and James McCullough. 
The  Remuneration  Committee  review  and  makes  recommendations  in  respect  of  the  Executive  Directors’ 
remuneration and benefits packages, including share options and the terms of their appointment. The Remuneration 
Committee also make recommendations to the Board concerning the allocation of share options to employees under 
the intended share option schemes. 

The Committee has not met during year ended 31 December 2021. 

Nomination Committee  

The  Nomination  Committee  comprises  Sir  Ian  Carruthers,  who  acts  as  chair,  and  James  McCullough.  The 
Nomination Committee will review and recommend nominees as new Directors to the Board.  The Committee has 
not met during year ended 31 December 2021. 

Internal control 

The Directors are responsible for ensuring that the Group maintains a system of internal control to provide them with 
reasonable assurance regarding the reliability of financial information used within the business and for publication 
and that the assets are safeguarded. There are inherent limitations in any system of internal control and accordingly 
even  the  most  effective  system  can  provide  only  reasonable,  but  not  absolute,  assurance  with  respect  to  the 
preparation of financial reporting and the safeguarding of assets. 

The Group, in administering its business, has put in place strict authorisation, approval and control levels within which 
senior management operates. These controls reflect the Group’s organisational structure and business objectives. 
The control system includes clear lines of accountability and covers all areas of the organisation. The Board operates 
procedures  which  include  an  appropriate  control  environment  through  the  definition  of  the  above  organisation 
structure and authority levels and the identification of the major business risks. 

Internal financial reporting 

The Directors are responsible for establishing and maintaining the Group’s system of internal reporting and as such 
have put in place a framework of controls to ensure that on-going financial performance is measured in a timely and 
correct manner and that risks are identified as early as is practicably possible. There is a comprehensive budgeting 
system and monthly management accounts are prepared which compare actual results against both the budget and 
the previous year. They are reviewed and approved by the Board and revised forecasts are prepared on a regular 
basis. 

22 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Corporate governance statement  
for the year ended 31 December 2021 (continued) 

Relations with shareholders 

The Company will report to Shareholders twice a year. The Company dispatches the notice of its Annual General 
Meeting, together with a description of the items of special business, at least 21 clear days before the meeting. Each 
substantially separate issue is the subject of a separate resolution, and all Shareholders have the opportunity to put 
questions to the Board at the Annual General Meeting. 

The Chair(s) of the Audit and Remuneration Committees normally attend the Annual General Meeting and will answer 
questions which may be relevant to their work. The Chairman advises the meeting of the details of proxy votes cast 
on  each  of  the  individual  resolutions  after  they  have  been  voted  on  in  the  meeting.  The  Chairman  and  the  Non-
Executive  Directors  intend  to  maintain  a  good  and  continuing  understanding  of  the  objectives  and  views  of  the 
Shareholders. 

Shareholders may contact the Company as follows: 

Tel: +44 (0)20 7933 8780 

Email: investors@vericidx.com 

Corporate social responsibility 

The Board recognises that the Group has a duty to be a good corporate citizen and is conscious that its business 
processes minimise harm to the environment, that it contributes as far as is practicable to the local communities in 
which it operates and takes a responsible and positive approach to employment practices.  

The Corporate Governance Statement was approved by the Board on 18 May 2022 and signed on its behalf by: 

Salim Hamir 
Company Secretary 

23 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the remuneration committee  
for the year ended 31 December 2021 

Statement of compliance 

This report does not constitute a Directors’ Remuneration Report in accordance with the Directors’  Remuneration 
Regulations 2007 which do not apply to the Company as it is not fully listed. This report sets out the Group policy on 
Directors’ remuneration, including emoluments, benefits and other share-based awards made to each Director. 

Policy on Executive Directors’ remuneration 

Remuneration  packages  are  designed  to  motivate  and  retain  the  Executive  Director  to  ensure  the  continued 
development  of  the  Group  and  to  reward  them  for  enhancing  value  to  shareholders.  The  main  elements  of  the 
remuneration package for the Executive Director are basic salary, performance-related bonuses, benefits and share 
based incentives. 

Directors’ remuneration - Audited 

The remuneration of the Directors for the year ended 31 December 2021 is shown below: 

Executive Director 
Sara Barrington 

Base 
Salary and 
fees 
US$ 

Pension 
US$ 

Benefits 
US$ 

Bonus 
US$ 

Year to 
31 
December 
2021 
US$ 

288,113 

10,487 

19,681 

97,500 

415,781 

288,113 

10,487 

19,681 

97,500 

415,781 

Non-Executive Directors 
Julian Baines 
Sir Ian Carruthers 
Dr Erik Lium 
James McCullough 
Dr  Lorenzo  Gallon  (appointed  18 
August 2021) 
Dr  Barbara  Murphy  (deceased  29 
June 2021) 

41,277 
34,397 
34,397 
34,397 
12,760 

17,199 

174,427 

- 
- 
- 
- 
- 

- 

- 

- 
- 
- 
- 
- 

- 

- 

- 
- 
- 
- 
- 

- 

- 

41,277 
34,397 
34,397 
34,397 
12,760 

17,199 

174,427 

Total fees and emoluments 

462,540 

10,487 

19,681 

97,500 

590,208 

Dr Erik Lium is not entitled to receive remuneration as he sits on the Board as a representative of the Icahn School 
of Medicine at Mount Sinai and his fees are paid to Mount Sinai. 

24 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the remuneration committee  
for the year ended 31 December 2021 (continued) 

The remuneration of the Directors for the period ended 31 December 2020 is shown below: 

Base Salary 
and fees 
US$ 

Pension 
US$ 

Benefits 
US$ 

Period to 
31 December 
2020 
US$ 

Executive Director 
Sara Barrington 

Non-Executive Directors 
Julian Baines 
Sir Ian Carruthers 
Dr Erik Lium 
James McCullough 
Dr Barbara Murphy 

92,292 

92,292 

6,721 
5,602 
5,602 
5,602 
5,602 
29,129 

Total fees and emoluments 

121,421 

- 

- 

- 
- 
- 
- 
- 
- 

- 

- 

- 

- 
- 
- 
- 
- 
- 

- 

92,292 

92,292 

6,721 
5,602 
5,602 
      5,602 
5,602 
29,129 

121,421 

25 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the remuneration committee  
for the year ended 31 December 2021 (continued) 

Share option plan 

On 28 October 2020 share options were granted to a number of directors and other parties under the Company’s 
unapproved share-option scheme. The options held by Directors as of 31 December 2021 were as follows: 

Option holder 

Option price per 
ordinary share 

Number of Ordinary 
Shares under option 

Exercise period 

Icahn  School  of  Medicine 
at Mount Sinai 

Sara Barrington 

£0.20 

£0.20 

708,739 

28 October 2020 – 27 October 2030 

5,669,913 

28 October 2020 – 27 October 2030 

Directors’ interests in the share capital of the Company are disclosed in the Directors’ Report on pages 15 to 18. 

Approved by the Board on 18 May 2022 and signed on its behalf by: 

Julian Baines 
Non-executive Chairman 

26 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the audit of the financial statements  
for the year ended 31 December 2021 

INDEPENDENT AUDITOR’S REPORT TO THE SHAREHOLDERS OF VERICI DX PLC 

Opinion 

We have audited the financial statements of Verici Dx plc (the “parent company”) and its subsidiary (the “group”) for 
the  year  ended  31  December  2021  which  comprise  the  Statement  of  Consolidated  Profit  or  Loss  and  Other 
Comprehensive  Income,  the  Consolidated  and  Company  Statements  of  Financial  Position,  the  Consolidated  and 
Company Statements of Cash Flows in Equity, the Consolidated and Company Statement of Changes in Equity and 
notes  to  the  financial  statements,  including  a  summary  of  significant  accounting  policies.  The  financial  reporting 
framework  that  has  been  applied  in  the  preparation  of  the  group  financial  statements  is  applicable  law  and  UK 
adopted International Accounting Standards (IFRSs). The financial reporting framework that has been applied in the 
preparation of the parent company financial statements is applicable law and United Kingdom Accounting Standards, 
including Financial Reporting Standard 101 Reduced Disclosures Framework (United Kingdom Generally Accepted 
Accounting Practice). 

In our opinion: 

• 

• 

• 

• 

the financial statements give a true and fair view of the state of the group’s and of the parent company’s 
affairs as at 31 December 2021 and of the group’s loss for the year then ended; 
the group financial statements have been properly prepared in accordance with UK adopted International 
Accounting Standards; 
the  parent  company  financial  statements  have  been  properly  prepared  in  accordance  with  Financial 
Reporting  Standard  101  Reduced  Disclosures  Framework  (United  Kingdom  Generally  Accepted 
Accounting Practice); and 
the financial statements have been prepared in accordance with the requirements of the Companies Act 
2006.  

Basis for opinion  

We conducted our audit in accordance with International Standards on Auditing (UK) (“ISAs (UK)”) and applicable 
law.  

Our responsibilities under those standards are further described in the auditor’s responsibilities for the audit of the 
financial statements section of our report. We are independent of the group and the company in accordance with the 
ethical requirements that are relevant to our audit of the financial statements in the UK, including the FRC’s Ethical 
Standard, and we have fulfilled our other ethical responsibilities in accordance with these requirements.  

We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion. 

Conclusions relating to going concern 

In  auditing  the  financial  statements,  we  have  concluded  that  the  Directors’  use  of  the  going  concern  basis  of 
accounting in the preparation of the financial statements is appropriate. Our evaluation of the Directors’ assessment 
of the Group and the Parent Company’s ability to continue to adopt the going concern basis of accounting included 
the following procedures: 

The going concern assessment period used by the Directors was at least 12 months from the date of the approval of 
the financial statements. We assessed the appropriateness of the approach, assumptions and arithmetic accuracy 
of the model used by management when performing their going concern assessment. 

27 

 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the audit of the financial statements  
for the year ended 31 December 2021 (continued) 

We evaluated the Directors’ assessment of the Group’s ability to continue as a going concern, including challenging 
the underlying data and key assumptions used to make the assessment. Additionally, we reviewed and challenged 
the results of management’s stress testing, to assess the reasonableness of economic assumptions on the Group’s 
solvency and liquidity position. 

Further details of the Directors’ assessment of going concern is provided in Note 2. 

Based  on  the  work  we  have  performed,  we  have  not  identified  any  material  uncertainties  relating  to  events  or 
conditions that, individually or collectively, may cast significant doubt on the company's ability to continue as a going 
concern for a period of at least twelve months from when the financial statements are authorised for issue.  

Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant 
sections of this report. 

Overview of our audit approach 

Materiality 
In planning and performing our audit we applied the concept of materiality. An item is considered material if it could 
reasonably be expected to change the economic decisions of a user of the financial statements. We used the concept 
of materiality to both focus our testing and to evaluate the impact of misstatements identified. 

Based on our professional judgement, we determined overall materiality for the group financial statements as a whole 
to be $350,000 based on 5% of the expected loss before tax at the planning stage. We did not consider it necessary 
subsequently to amend our assessment. Profit or loss before tax is a generally accepted auditing benchmark. 

We use a different level of materiality (“performance materiality”) to determine the extent of our testing for the audit 
of  the  financial  statements.  Performance  materiality  is  set  based  on  the  audit  materiality  as  adjusted  for  the 
judgements made as to the entity risk and our evaluation of the specific risk of each audit area having regard to the 
internal control environment. We determined the group performance materiality to be $245,000. 

Where considered appropriate, performance materiality may be reduced to a lower level, such as for related party 
transactions and Directors’ remuneration. 

We  agreed  with  the  Audit  Committee  to  report  to  it  all  identified  errors  in  excess  of  $17,500.  Errors  below  that 
threshold would also be reported to it if, in our opinion as auditor, disclosure was required on qualitative grounds. 

The  parent  company  materiality  was  assessed  as  $240,000  based  on  approximately  1%  of  total  assets  at  the 
planning stage. Performance materiality was set at $168,000. Parent company triviality was $12,000. 

Overview of the scope of our audit 
The company’s operations are based in the UK and the USA. In view of the early stage of development of the group’s 
business activities the audit team performed a full scope audit on the group from the UK as a single component.  

28 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the audit of the financial statements  
for the year ended 31 December 2021 (continued) 

Key audit matters 

Key audit matters are those matters that, in our professional judgment, were of most significance in our audit of the 
financial statements of the current period and include the most significant assessed risks of material misstatement 
(whether or not due to fraud) we identified, including those which had the greatest effect on the overall audit strategy, 
the  allocation  of  resources  in  the  audit;  and  directing  the  efforts  of  the  engagement  team.  These  matters  were 
addressed in the context of our audit of the financial statements as a whole, and in forming our opinion thereon, and 
we do not provide a separate opinion on these matters   

There were no matters which we consider should be separately reported as key audit matters. 

Other information 

The  Directors  are  responsible  for  the  other  information  contained  within  the  annual  report.  The  other  information 
comprises the information included in the Annual Report, other than the financial statements and our auditor’s report 
thereon.  Our  opinion  on  the  financial  statements  does  not  cover  the  other  information  and,  except  to  the  extent 
otherwise explicitly stated in our report, we do not express any form of assurance conclusion thereon. 

Our responsibility is to read the other information and, in doing so, consider whether the other information is materially 
inconsistent with the financial statements or our knowledge obtained in the audit or otherwise appears to be materially 
misstated.  If  we  identify  such  material  inconsistencies  or  apparent  material  misstatements,  we  are  required  to 
determine whether this gives rise to a material misstatement in the financial statements themselves. If, based on the 
work we have performed, we conclude that there is a material misstatement of this other information, we are required 
to report that fact.  

We have nothing to report in this regard. 

Opinion on other matters prescribed by the Companies Act 2006 

In our opinion, based on the work undertaken in the course of our audit:  
• 

the information given in the strategic report and the Directors’ report for the financial year for which the financial 
statements are prepared is consistent with the financial statements; and 
the  strategic  report  and  the  Directors’  report  have  been  prepared  in  accordance  with  applicable  legal 
requirements. 

• 

Matters on which we are required to report by exception 

In light of the knowledge and understanding of the company and its environment obtained in the course of the audit, 
we have not identified material misstatements in the strategic report or the Directors’ report. 

We have nothing to report in respect of the following matters where the Companies Act 2006 requires us to report to 
you if, in our opinion: 

•  adequate accounting records have not been kept by the company, or returns adequate for our audit have not 

been received from branches not visited by us; or 
the financial statements are not in agreement with the accounting records and returns; or 

• 
•  certain disclosures of Directors’ remuneration specified by law are not made; or 
•  we have not received all the information and explanations we require for our audit. 

29 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the audit of the financial statements  
for the year ended 31 December 2021 (continued) 

Responsibilities of the Directors for the financial statements 

As explained more fully in the Directors’ responsibilities statement, the Directors are responsible for the preparation 
of the financial statements and for being satisfied that they give a true and fair view, and for such internal control as 
the Directors determine is necessary to enable the preparation of financial statements that are free from material 
misstatement, whether due to fraud or error. 

In preparing the financial statements, the Directors are responsible for assessing the company’s ability to continue 
as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of 
accounting unless the Directors either intend to liquidate the company or to cease operations, or have no realistic 
alternative but to do so. 

Auditor’s responsibilities for the audit of the financial statements 

Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from 
material  misstatement,  whether  due  to  fraud  or  error,  and  to  issue  an  auditor’s  report  that  includes  our  opinion. 
Reasonable assurance is a high level of assurance but is not a guarantee that an audit conducted in accordance 
with ISAs (UK) will always detect a material misstatement when it exists. 

Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could 
reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements. 

Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in 
line with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including 
fraud. The extent to which our procedures are capable of detecting irregularities, including fraud is detailed below:  

We obtained an understanding of the legal and regulatory frameworks within which the company operates, focusing 
on those laws and regulations that have a direct effect on the determination of material amounts and disclosures in 
the financial statements. The laws and regulations we considered in this context were the Companies Act 2006 and 
taxation legislation. Technical, clinical or regulatory laws and regulations which are inherent risks in drug development 
are mitigated and managed by the Board and management in conjunction with expert regulatory consultants in order 
to monitor the latest regulations and planned changes to the regulatory environment. 

We identified the greatest risk of material impact on the financial statements from irregularities, including fraud, to 
be the override of controls by management. Our audit procedures to respond to these risks included enquiries of 
management about their own identification and assessment of the risks of irregularities, sample testing on the 
posting of journals and reviewing accounting estimates for biases.  

Owing  to  the  inherent  limitations  of  an  audit,  there  is  an  unavoidable  risk  that  we  may  not  have  detected  some 
material misstatements in the financial statements, even though we have properly planned and performed our audit 
in  accordance  with  auditing  standards.    We  are  not  responsible  for  preventing  non-compliance  and  cannot  be 
expected to detect non-compliance with all laws and regulations.  

These inherent limitations are particularly significant in the case of misstatement resulting from fraud as this may 
involve  sophisticated  schemes  designed  to  avoid  detection,  including  deliberate  failure  to  record  transactions, 
collusion or the provision of intentional misrepresentations. 

A  further  description  of  our  responsibilities  for  the  audit  of  the financial  statements  is  located  on the Financial 
Reporting Council’s website at: www.frc.org.uk/auditorsresponsibilities. This description forms part of our auditor’s 
report. 

30 

 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Report of the audit of the financial statements  
for the year ended 31 December 2021 (continued) 

Use of our report 

This report is made solely to the company’s members, as a body, in accordance with Chapter 3 of Part 16 of the 
Companies Act 2006. Our audit work has been undertaken so that we might state to the company’s members those 
matters we are required to state to them in an auditor’s report and for no other purpose. To the fullest extent permitted 
by law, we do not accept or assume responsibility to anyone other than the company and the company’s members 
as a body, for our audit work, for this report, or for the opinions we have formed. 

Stephen Bullock  
(Senior Statutory Auditor) 
for and on behalf of Crowe U.K. LLP Statutory Auditor, London 
18.May 2022 

31 

 
 
 
 
 
 
 
 
 
Verici Dx plc 

Consolidated statement of profit or loss and other comprehensive income 
for the year ended 31 December 2021 

Administrative expenses 
Depreciation and amortisation 
Exceptional expense – share based payments 
Exceptional expense – costs of listing 

Loss from operations 

Finance expense 

Loss before tax 

Tax expense 

Note 

5 

19 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

(7,151,244) 
(437,756) 
(740,829) 
- 
_________ 

(1,402,926) 
(192,235) 
(2,794,625) 
(275,508) 
_________ 

(8,329,829) 

(4,665,294) 

9 

- 
_________ 

(69,713) 
_________ 

(8,329,829) 

(4,735,007) 

10 

- 
_________ 

- 
_________ 

Loss from continuing operations 

(8,329,829) 

(4,735,007) 

Other comprehensive income: 

Exchange gains arising on translation of foreign operations 

Loss and total comprehensive income attributable to the 
owners of the Company 

Earnings per share attributable to the  
ordinary equity holders of the parent 

11 

Loss per share 
Basic and diluted (US$ 

(50,002) 
_________ 

1,028,907 
_________ 

(8,379,831) 
_________ 

(3,706,100) 
_________ 

($0.059) 

_________ 

($0.0546) 
_________ 

The results reflected above relate to continuing operations 

The notes on pages 41 to 62 form part of these financial statements. 

32 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Consolidated statement of financial position 
as at 31 December 2021 

Assets 
Current assets 
Trade and other receivables 
Cash and cash equivalents 

Non-current assets 
Property, plant and equipment  
Intangible assets 

Total assets 

Liabilities 
Current liabilities 
Trade and other payables 

NET ASSETS 

Issued capital and reserves attributable to 
owners of the parent 
Share capital 
Share premium reserve 
Share-based payments reserve 
Foreign exchange reserve 
Retained earnings 

TOTAL EQUITY 

Note 

2021 
US$ 

2020 
US$ 

15 

12 
13 

655,847 
10,339,788 
_________ 

323,224 
17,751,087 
_________ 

10,995,635 
_________ 

18,074,311 
_________ 

785,736 
2,007,623 
_________ 

464,042 
1,767,424 
_________ 

2,793,359 
_________ 

2,231,466 
_________ 

13,788,994 
_________ 

20,305,777 
_________ 

16 

1,804,109 
_________ 

681,890 
_________ 

11,984,885 
_________ 

19,623,887 
_________ 

17 
18 
18 

181,614 
20,353,748 
3,535,454 
978,905 
(13,064,836) 
_________ 

181,614 
20,353,748 
2,794,625 
1,028,907 
(4,735,007) 
_________ 

11,984,885 
_________ 

19,623,887 
_________ 

The financial statements on pages 32 to 62 were approved and authorised for issue by the Board of Directors on 18 
May 2022 and were signed on its behalf by: 

Julian Baines - Director 

Sara Barrington - Director 

Company Number 12567827 

The notes on pages 41 to 62 form part of these financial statements. 

33 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Company statement of financial position 
as at 31 December 2021 

Assets 
Current assets 
Trade and other receivables 
Cash and cash equivalents 

Non-current assets 
Property, plant and equipment  
Intangible assets 
Investment in subsidiary undertaking 

Total assets 

Liabilities 
Current liabilities 
Trade and other payables 

NET ASSETS 

Issued capital and reserves attributable to 
owners of the parent 
Share capital 
Share premium reserve 
Share-based payments reserve 
Foreign exchange reserve 
Retained earnings 

TOTAL EQUITY 

Note 

2021 
US$ 

2020 
US$ 

15 

12 
13 
14 

8,344,064 
10,024,102 
_________ 

1,263,856 
17,578,901 
_________ 

18,368,166 
_________ 

18,842,757 
_________ 

249,872 
1,566,331 
10 
_________ 

441,803 
1,651,109 
10 
_________ 

1,816,213 
_________ 

2,092,922 
_________ 

20,184,379 
_________ 

20,935,679 
_________ 

16 

181,129 
_________ 

187,979 
_________ 

20,003,250 
_________ 

20,747,700 
_________ 

17 
18 
18 

181,614 
20,353,748 
247,660 
867,950 
(1,647,722) 
_________ 

181,614 
20,353,748 
189,523 
1,073,823 
(1,051,008) 
_________ 

20,003,250 
_________ 

20,747,700 
_________ 

The Company has taken advantage of the exemptions under section 408 of the Companies Act 2006 not to present 
the  Company  profit  or  loss  statement.  The  loss  of  the  Company  for  the  year  ended  31  December  2021  was 
US$596,714. The financial statements on pages 32 to 62 were approved and authorised for issue by the Board of 
Directors on  18 May 2022 and were signed on its behalf by: 

Julian Baines - Director 

Sara Barrington - Director 

Company Number 12567827 

The notes on pages 41 to 62 form part of these financial statements. 

34 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Consolidated statement of cash flows 
for the year ended 31 December 2021 

Cash flows from operating activities 
Loss from operations 
Adjustments for: 
Depreciation of property, plant and equipment 
Amortisation of intangible fixed assets 
Finance expense 
Share-based payment expense 

Increase in trade and other receivables 
Increase in trade and other payables 
Settled by Convertible Loan Note 
Income taxes paid 

Net cash outflow from operating activities  

Cash flows from investing activities 
Purchases of property, plant and equipment 
Purchase of intangibles 

Net cash used in investing activities 

Cash flows from financing activities 
Issue of ordinary shares 
Expenses of share issue 
Loan repayments 

Net cash from financing activities 

Net (reduction) / increase in cash and cash equivalents 
Cash and cash equivalents at beginning of year 
Exchange (losses) / gains on cash and cash equivalents 

Note 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

23 

(8,329,829) 

(4,665,294) 

295,178 
142,578 
- 
740,829 
_________ 

123,242 
68,993 
(69,713) 
2,794,625 
_________ 

(7,151,244) 

(1,748,147) 

(330,967) 
1,145,7674 
- 
- 
_________ 

(323,224) 
681,890 
535,164 
- 
_________ 

(6,336,444) 
_________ 

(854,317) 
_________ 

(617,940) 
(347,919) 
_________ 

(25,851) 
(132,259) 
_________ 

(965,859) 

(158,110) 

- 
- 
(73,548) 
_________ 

18,795,500 
(959,993) 
- 
_________ 

(73,548) 

17,835,507 

(7,375,851) 
17,751,087 
(35,448) 
_________ 

16,823,080 
- 
928,007 
_________ 

Cash and cash equivalents at end of year 

4 

10,339,788 
_________ 

17,751,087 
_________ 

The notes on pages 41 to 62 form part of these financial statements. 

35 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Company statement of cash flows 
for the year ended 31 December 2021 

Cash flows from operating activities 
Loss for the period 
Adjustments for: 
Depreciation of property, plant and equipment 
Amortisation of intangible fixed assets 
Finance expense 
Share-based payment expense 

Increase in trade and other receivables 
Increase in trade and other payables 
Settled by Convertible Loan Note 
Income taxes paid 

Net cash outflow from operating activities  

Cash flows from investing activities 
Purchase of intangibles 

Net cash used in investing activities 

Cash flows from financing activities 
Issue of ordinary shares 
Expenses of share issue 
Loan repayments 

Note 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

(596,714) 

(981,295) 

190,863 
123,973 
- 
58,137 
_________ 

119,630 
68,274 
(69,713) 
189,523 
_________ 

(223,741) 

(673,581) 

(7,235,782) 
18,057 
- 
- 
_________ 

(1,263,867) 
187,979 
535,164 
- 
_________ 

(7,441,466) 
_________ 

(1,214,305) 
_________ 

(4,337) 
_________ 

(15,225) 
_________ 

(4,337) 

(15,225) 

- 
- 
(73,548) 
_________ 

18,795,500 
(959,993) 
- 
_________ 

Net (outflow) / inflow from financing activities 

(73,548) 

17,835,507 

Net (reduction) / increase in cash and cash equivalents 
Cash and cash equivalents at beginning of year 
Exchange (losses) / gains on cash and cash equivalents 

Cash and cash equivalents at end of year 

(7,519,351) 
17,578,901 
(35,448) 
_________ 

16,605,977 
- 
972,924 
_________ 

4 

10,024,102 
_________ 

17,578,901 
_________ 

The notes on pages 41 to 62 form part of these financial statements. 

36 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 

1  General information 

The principal activity of Verici Dx plc (the “Company”) is the development of prognostic and diagnostic tests for 
kidney transplant patients.  

The Company is a public limited company incorporated in England and Wales and domiciled in the UK. The 
address of the registered office is Avon House, 19 Stanwell Road, Penarth, Cardiff CF64 2EZ and the company 
number is 12567827. 

The Company was incorporated as Verici Dx Limited on 22 April 2020 as a private company and on 9 September 
2020 the Company was re-registered as a public company and changed its name to Verici Dx plc. 

2 

Summary of significant accounting policies 

The  principal  accounting  policies  adopted  in  the  preparation  of  the  historical  financial  information  of  the 
Company, which have been applied consistently to the period presented, are set out below: 

Basis of preparation 

The financial statements have been prepared in accordance with International Financial Reporting Standards 
as adopted by the UK in conformity with the Companies Act 2006. The financial statements of the Company for 
the year ended 31 December 2021 are prepared in accordance with applicable law and UK Accounting Practice, 
included FRS 101 “Reduced Disclosure Framework”. 

The  functional  currency  and  the  presentational  currency  of  the  Company  is  United  States  dollars  (“USD”  or 
“US$”) as this is the currency of the primary economic environment that the Company operates in.  

New  standards  are  not  expected  to  impact  the  Company  or  Group  as  they  are  either  not  relevant  to  the 
Company's  or  Group’s  activities  or  require  accounting  which  is  consistent  with  the  Company's  and  Group’s 
current accounting policies. The Directors have considered those standards and interpretations which have not 
been applied in these financial statements but which are relevant to the Company's or Group’s operations that 
are in issue but not yet effective and do not consider that they will have a material effect on the future results of 
the Company or Group. 

Other 

The Group does not expect any other standards issued by the IASB, but not yet effective, to have a material 
impact on the group. 

Measurement convention 

The financial information has been prepared under the historical cost convention. Historical cost is generally 
based on the fair value of the consideration given in exchange for assets. 

The  preparation  of  the  financial  information  in  compliance  with  IFRS  requires  the  use  of  certain  critical 
accounting  estimates  and  management  judgements  in  applying  the  accounting  policies.  The  significant 
estimates and judgements that have been made and their effect is disclosed in note 3. 

Basis of consolidation 

Where the Company has control over an investee, it is classified as a subsidiary. The Company controls an 
investee if all three of the following elements are present: power over the investee, exposure to variable returns 
from  the  investee,  and  the  ability  of  the  investor  to  use  its  power  to  affect  those  variable  returns.  Control  is 
reassessed whenever facts and circumstances indicate that there may be a change in any of these elements 
of control. 

41 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

2 

Summary of significant accounting policies (continued) 

Basis of consolidation (continued) 

The consolidated financial statements present the results of the Company and its subsidiaries ("the Group") as 
if they formed a single entity. Intercompany transactions and balances between group companies are therefore 
eliminated in full. 

The consolidated financial statements incorporate the results of business combinations using the acquisition 
method.  In  the  statement  of  financial  position,  the  acquiree's  identifiable  assets,  liabilities  and  contingent 
liabilities are initially recognised at their fair values at the acquisition date.  The results of acquired operations 
are included in the consolidated statement of profit or loss and other comprehensive income from the date on 
which control is obtained. They are deconsolidated from the date on which control ceases. 

Going concern 

The Group is in the development phase of its business and has not generated any revenues. At 31 December 
2021 the Group has available cash resources of $10,339,788.  Subsequent to the year end on 11 March 2022 
the Company closed a funding raising GBP10.0m before expenses by the issue of 28,571,429 new shares.    

The Board has considered the impact of the ongoing COVID-19 pandemic. There has been minimal impact on 
the Company to date. Given the impact of COVID-19 in the economy generally, the Board has performed a 
number of stress tests to assess the ability of the Company to continue as a going concern. 

The Directors have prepared cash flow forecasts for the Group for a review period of 12 months from the date 
of approval of this historical financial information. These forecasts reflect an assessment of current and future 
market conditions and their impact on the Company’s future cash flow performance.  

The  forecasts  have  been  sensitised  for  additional  costs  which  may  be  incurred  in  the  review  period.  In  the 
sensitised scenario, the forecasts indicate the Company would still have sufficient cash to continue as a going 
concern. 

Having considered the points above, the Directors remain confident in the long-term future prospects for the 
Group, and their ability to continue as a going concern for the foreseeable future. They therefore adopt the going 
concern basis in preparing the historical financial information of the Group. 

Taxation 

Income tax expense represents the sum of the tax currently payable and deferred tax. 

Current tax 

Current tax payable is based on taxable profit for the year. Taxable profit differs from net profits as reported in 
the income statement because it excludes items of income or expense that are taxable or deductible in other 
years and it further excludes items that are never taxable or deductible. The Company’s liability for current tax 
is calculated using tax rates that have been enacted or substantially enacted by the reporting end date. 

42 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

2 

Summary of significant accounting policies (continued) 

Deferred tax 

Deferred tax is the tax expected to be payable or recoverable on temporary differences between the carrying 
amounts of assets and liabilities in the historical financial information and the corresponding tax bases used in 
the computation of taxable profit, and is accounted for using the balance sheet liability method. Deferred tax 
liabilities are generally recognised for all taxable temporary differences and deferred tax assets are recognised 
to  the  extent  that  it  is  probable  that  taxable  profits  will  be  available  against  which  deductible  temporary 
differences can be utilised. Such assets and liabilities are not recognised if the temporary differences arises 
from goodwill or from the initial recognition of other assets and liabilities in a transaction that affects neither the 
tax profit nor the accounting profit. 

The carrying amount of deferred tax assets is reviewed at each reporting end date and reduced to the extent 
that it is no longer probable that sufficient taxable profits will be available to allow all or part of the asset to be 
recovered. Deferred tax is calculated at the tax rates that are expected to apply in the period when the liability 
is settled or the asset is realised. Deferred tax is charged or credited in the income statement, except when it 
relates to items charged or credited directly to equity, in which case the deferred tax is also dealt with in equity. 
Deferred tax assets and liabilities are offset when the company has a legally enforceable right to offset current 
tax  assets  and  liabilities  and  the  deferred  tax  assets  and  liabilities  relate  to  taxes  levied  by  the  same  tax 
authority. 

Share-based payments 

Where equity settled share options are awarded to employees, the fair value of the options at the date of grant 
is charged to the consolidated statement of comprehensive income over the vesting period.  Non-market vesting 
conditions  are  taken  into  account  by  adjusting  the  number  of  equity  instruments  expected  to  vest  at  each 
reporting date so that, ultimately, the cumulative amount recognised over the vesting period is based on the 
number of options that eventually vest.  Non-vesting conditions and market vesting conditions are factored into 
the fair value of the options granted.  As long as all other vesting conditions are satisfied, a charge is made 
irrespective of whether the market vesting conditions are satisfied.  The cumulative expense is not adjusted for 
failure to achieve a market vesting condition or where a non-vesting condition is not satisfied. 

Where  equity  instruments  are  granted  to  persons  other  than  employees,  the  consolidated  statement  of 
comprehensive income is charged with the fair value of goods and services received. 

Foreign currency translation 

a)  Function and presentational currency 
Items included in the financial statements of the Group are measured using USD, the currency of the primary 
economic  environment  in  which  the  entity  operates  (‘the  functional  currency’),  which  is  also  the  Company’s 
presentation currency. 

b)  Transactions and balances 
Foreign currency transactions are translated into the functional currency using the exchange rates prevailing at 
the  dates  of  the  transactions.  Foreign  exchange  gains  and  losses  resulting  from  the  settlement  of  such 
transactions and from the translation at year-end exchange rates, of monetary assets and liabilities denominated 
in foreign currencies to USD, are recognised in the income statement. 

43 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

2 

Summary of significant accounting policies (continued) 

Intangible assets  

Intangible assets are measured at cost less accumulated amortisation and any accumulated impairment losses.  

Patents are recognised at fair value at the acquisition date. Patents have a finite useful life and are subsequently 
carried at cost less accumulated amortisation and impairment losses. 

The Company amortises intangible assets with a limited useful life on a straight-line basis. The following rates 
are applied: 

Licence and patents - the shorter of the remaining life of the license and 15 years  

Tangible assets 

Tangible fixed assets are stated at cost net of accumulated depreciation and accumulated impairment losses. 
Costs comprise purchase costs together with any incidental costs of acquisition. 

Depreciation is provided to write down the cost less the estimated residual value of all tangible fixed assets by 
equal instalments over their estimated useful economic lives on a straight-line basis. The following rates are 
applied: 

Plant and machinery – 3 years 

The assets’ residual values, useful lives and depreciation methods are reviewed, and adjusted prospectively if 
appropriate, if there is an indication of a significant change since the last reporting date. Low value equipment 
including computers is expensed as incurred. 

Impairment of tangible and intangible assets 

At each reporting end date, the Company reviews the carrying amounts of its tangible and intangible assets to 
determine  whether  there  is  any  indication  that  those  assets  have  suffered  an  impairment  loss.  If  any  such 
indication  exists,  the  recoverable  amount  of  the  asset  is  estimated  in  order  to  determine  the  extent  of  the 
impairment loss (if any). Where it is not possible to estimate the recoverable amount of an individual asset, the 
Company estimates the recoverable amount of the cash-generating unit to which the asset belongs. 

The recoverable amount is the higher of fair value less costs to sell and value in use. In assessing value in use, 
the estimated future cash flows are discounted to their present value using a pre-tax discount rate that reflects 
current  market  assessments  of  the  time  value  of  money  and  the  risks  specific  to  the  asset  for  which  the 
estimates of future cash flows have not been adjusted. 

If the recoverable amount of an asset (or cash-generating unit) is estimated to be less than its carrying amount, 
the carrying amount of the asset (or cash-generating unit) is reduced to its recoverable amount. An impairment 
loss is recognised immediately in profit and loss, unless the relevant asset is carried at a revalued amount, in 
which case the impairment loss is treated as a revaluation decrease. 

Where  an  impairment  subsequently  reverses,  the  carrying  amount  of  the  asset  (or  cash-generating  unit)  is 
increased to the revised estimate of its recoverable amount, but so that the increased carrying amount does not 
exceed the carrying amount that would have been determined had no impairment loss been recognised for the 
asset (or cash-generating unit) in prior years. A reversal of an impairment loss is recognised immediately in 
profit and loss. 

44 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

2 

Summary of significant accounting policies (continued) 

Financial instruments 

The  Company  classifies  financial  instruments,  or  their  component  parts,  on  initial  recognition  as  a  financial 
asset,  a  financial  liability  or  an  equity  instrument  in  accordance  with  the  substance  of  the  contractual 
arrangement. Financial assets and financial liabilities are recognised on the statement of financial position when 
the Company becomes a party to the contractual provisions of the instrument. 

a)  Financial assets 

Financial assets are classified, at initial recognition, at amortised cost or carrying value.  The classification of 
financial assets at initial recognition depends on the financial asset’s contractual cash flow characteristics and 
the Company’s business model for managing them. 

The  classification  depends  on  the  purpose  for  which  the  financial  assets  were  acquired.  Management 
determines the classification of its financial assets at initial recognition and re-evaluates this classification at 
every reporting date.  

As at the reporting date, the Company did not have any financial assets subsequently measured at fair value. 

b)  Financial liabilities 

All financial liabilities are initially measured at fair value and, in the case of loans and borrowings, net of directly 
attributable transaction costs. They are subsequently measured at amortised cost, where applicable, using the 
effective interest method, with interest expense recognised on an effective yield basis. 

c)  Cash and cash equivalents 

Cash and cash equivalents comprise cash balances and deposits with a maturity of less than three months at 
balance sheet date. 

Provisions 

A  provision  is  recognised  in  the  statement  of  financial  position  when  the  Group  has  a  present  legal  or 
constructive  obligation  as  a  result  of  a  past  event,  that  can  be  reliably  measured,  and  it  is  probably  that  an 
outflow  of  economic  benefits  will  be  required  to  the  settle  the  obligation.  Provisions  are  determined  by 
discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability. 

Financing expenses 

Financing expenses comprise interest payable and finance charges on shares classified as liabilities. Foreign 
exchange gains and losses arising on foreign currency transactions are reported within administrative expenses 
in the statement of comprehensive income. 

Interest  payable  is  recognised  in  the  statement  of  comprehensive  income  as  it  accrues,  using  the  effective 
interest method. 

Exceptional items 

Items considered of such significance  to enable the reader to better understand the results for the year are 
presented separately as exceptional items on the face of the statement of comprehensive income. 

45 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

2 

Summary of significant accounting policies (continued) 

Operating segments 

The  directors  are  of  the  opinion  that  the  business  of  the  Group  comprises  a  single  activity,  that  of  the 
development of prognostic and diagnostic tests for kidney transplant patients. Consequently, all activities relate 
to this segment.  

All the non-current assets of the Company are located in, or primarily relate to, the USA 

3 

Judgements and key sources of estimation uncertainty 

The preparation of the Company’s historical financial information under UK IFRS requires  the  Directors  to 
make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure 
of contingent assets and liabilities. Estimates and judgements are continually evaluated and are based on 
historical  experience  and  other  factors  including  expectations  of  future  events  that  are  believed  to  be 
reasonable under the circumstances. Actual results may differ from these estimates. 

The Directors consider that the following estimates and judgements are likely to have the most significant 
effect on the amounts recognised in the financial information. 

Carrying value of  intangible assets, property, plant and equipment 
In determining whether there are indicators of impairment of the Company’s intangible assets, the Directors 
take  into  consideration  various  factors  including  the  economic  viability  and  expected   future  financial 
performance of the asset and when it relates to the intangible assets arising on a business combination, the 
expected future performance of the business acquired. 

4 

Financial instruments - Risk Management 

The Group is exposed through its operations to the following financial risks: 

-  Credit risk 
-  Foreign exchange risk 
- 
Liquidity risk and 
-  Capital disclosures 

The Group is exposed to risks that arise from its use of financial instruments.  This note describes the Group's 
objectives, policies and processes for managing those risks and the methods used to measure them.  Further 
quantitative information in respect of these risks is presented throughout these financial statements. 

(i) Principal financial instruments 

The principal financial instruments used by the Group, from which financial instrument risk arises, are as follows: 

-  Cash and cash equivalents 
-  Trade and other payables 

46 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

4 

Financial instruments - Risk Management (continued) 

Principal financial instruments (continued) 

(ii) Financial instruments by category 

Financial asset 

Cash and cash equivalents 
Trade and other receivables 

Total financial assets 

Financial liabilities 

Group 
Amortised 
cost 
2021 
US$ 

10,339,788 
610,944 
_________ 

Company 
Amortised 
cost 
2021 
US$ 

10,024,102 
117,780 
_________ 

Group 
Amortised 
cost 
2020 
US$ 

17,751,087 
323,224 
_________ 

Company 
Amortised 
cost 
2020 
US$ 

17,578,901 
236,508 
_________ 

10,950,732 
_________ 

10,141,882 
_________ 

18,074,311 
_________ 

17,815,409 
_________ 

Group 
Amortised 
cost 
2021 
US$ 

Company 
Amortised 
cost 
2021 
US$ 

Group 
Amortised 
cost 
2020 
US$ 

Company 
Amortised 
cost 
2020 
US$ 

Trade and other payables and loan 

1,754,109 
_________ 

131,129 
_________ 

681,890 
_________ 

187,979 
_________ 

Total financial liabilities 

1,754,109 
_________ 

131,129 
_________ 

681,890 
_________ 

187,979 
_________ 

(iii) Financial instruments not measured at fair value 

Financial  instruments  not  measured  at  fair  value  includes  cash  and  cash  equivalents,  trade  and  other 
receivables, and trade and other payables. 

Due to their short-term nature, the carrying value of cash and cash equivalents, trade and other receivables, 
and trade and other payables approximates their fair value.  

47 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

4 

Financial instruments - Risk Management (continued) 

(iv) Financial instruments measured at fair value 

General objectives, policies and processes 

The  Board  has  overall  responsibility  for  the  determination  of  the  Group's  risk  management  objectives  and 
policies and, whilst retaining ultimate responsibility for them, it has delegated the authority for designing and 
operating  processes  that  ensure  the  effective  implementation  of  the  objectives  and  policies  to  the  Group's 
finance function.   

The overall objective of the Board is to set policies that seek to reduce risk as far as possible without unduly 
affecting the Group's competitiveness and flexibility.  Further details regarding these policies are set out below: 

Credit risk 

Credit risk is the risk of financial loss to the Group if a customer or counterparty to a financial instrument fails to 
meet its contractual obligations. Due to the absence of revenue, the Group’s exposure to credit risk is on cash 
at bank.  The Company only deposits cash with major banks with high quality credit standing for amounts in 
excess of US$500,000. 

Cash in bank and short-term deposits 

The credit quality of cash has been assessed by reference to external credit rating, based on Standard and 
Poor’s long-term / senior issuer rating: 

Bank A 
Bank B 

Bank A 
Bank B 

Group 
2021 
Cash 
at bank 
US$ 

10,024,102 
315,686 
_________ 

10,339,788 
_________ 

Group 
2020 
Cash 
at bank 
US$ 

17,578,901 
172,186 
_________ 

17,751,087 
_________ 

Company 
2021 

Rating 

A+ 

Company 
2020 

Rating 

A+ 

Company 
2021 
Cash 
at bank 
US$ 

10,024,102 
- 
_________ 

10,024,102 
_________ 

Company 
2020 
Cash 
at bank 
US$ 

17,578,901 
- 
_________ 

17,578,901 
_________ 

Group 
2021 

Rating 

A+ 

Group 
2020 

Rating 

A+ 

48 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

4 

Financial instruments - Risk Management (continued) 

Foreign exchange risk 

Foreign exchange risk arises when individual Group entities enter into transactions denominated in a currency 
other  than  their  functional  currency.    The  Group's  policy  is,  where  possible,  to  allow  group  entities  to  settle 
liabilities denominated in their functional currency. In the period before commercial revenues US dollars are 
transferred from the Company to its US subsidiary to enable it to meet its local obligations.  Currently the Group’s 
liabilities are either US dollar or UK sterling.  No forward contracts or other financial instruments are entered 
into to hedge foreign exchange movements, with funds being transferred from the Company to its US subsidiary 
using spot rates.   

As  at  31  December  2021  assets  held  in  Sterling  amounted  to  US$3,538,160  (2020  -  US$15,844,022)  and 
liabilities held in Sterling amounted to US$131,129 (2020 - US$187,979).   

The  effect  of  a 5%  strengthening  of  the  Sterling  against  US  dollar  at  the  reporting  date  on  the  Sterling 
denominated net assets carried at that date would, all other variables held constant, have resulted in a decrease 
in post-tax loss for the period and increase of net assets of US$170,351 (2020 – US$782,802).  A 5% weakening 
in  the  exchange  rate  would,  on  the  same  basis,  have  increased  post-tax  loss  and  decreased  net  assets  by 
US$170,351 (2020 – US$782,802). 

Liquidity risk 

Liquidity risk is the risk that the Group will encounter difficulty in meeting its financial obligations as they fall due.  
This risk is managed by the production of rolling cash flow projections.  The Group’s continued future operations 
depend on its ability to raise sufficient working capital through the issue of share capital and generating revenue. 

The following table sets out the contractual maturities (representing undiscounted contractual cash-flows) of 
financial liabilities which can all be met from the cash resources currently available: 

Group 

At 31 December 2021 

Trade and other payables 

Total 

Company 

At 31 December 2021 

Trade and other payables 

Total 

Up to 3 
months 
US$ 

Between 
3 and 12 
months 
US$ 

159,534 
_________ 

- 
_________ 

159,534 
_________ 

- 
_________ 

Up to 3 
months 
US$ 

Between 
3 and 12 
months 
US$ 

16,112 
_________ 

- 
_________ 

16,112 
_________ 

- 
_________ 

49 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

4 

Financial instruments - Risk Management (continued) 

Group 

At 31 December 2020 

Trade and other payables 
Loan 

Total 

Company 

At 31 December 2020 

Trade and other payables 
Loan 

Total 

Capital Disclosures 

Up to 3 
months 
US$ 

Between 
3 and 12 
months 
US$ 

394,331 
73,548 
_________ 

- 
- 
_________ 

467,879 
_________ 

- 
_________ 

Up to 3 
months 
US$ 

Between 
3 and 12 
months 
US$ 

44,912 
73,548 
_________ 

- 
- 
_________ 

118,460 
_________ 

- 
_________ 

The  Group  monitors  "adjusted  capital"  which  comprises  all  components  of  equity  (i.e.  share  capital,  share 
premium, and accumulated losses).  

The  Group's  objectives  when  maintaining  capital  are  to  safeguard  the  entity's  ability  to  continue  as  a  going 
concern. 

5 

Expenses by nature 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

2,393,384 
295,178 
142,578 
2,809,435 
250,000 
921,270 
309,067 
(182,010) 
1,390,927 

2,852,641 
123,242 
68,993 
355,107 
- 
553,454 
200,836 
159,538 
75,975 

Employee benefit expenses (see note 7) 
Depreciation of property, plant and equipment  
Amortisation of intangible assets 
Research and development costs 
Licenses 
Professional costs 
Share-based payment expense for non-employees 
Foreign exchange (gain) / losses 
Other costs 

50 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

6 

Auditors’ remuneration  

During the year the Group obtained the following services from the Company’s auditor: 

Fees payable to the Company’s auditor for the audit of the parent 
Company and consolidated financial statements 
Fees payable to the Company’s auditor for other services: 
Tax advisory and compliance services 
Service for finance related transactions 

Total 

7 

Employee benefit expenses 

Employee benefit expenses (including directors) comprise: 

Wages and salaries 
Benefits 
Share-based payment expense (note 19) 
Social security contributions and similar taxes 
Pension contributions 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

43,270 

47,049 

818 
- 
_________ 

6,933 
57,024 
_________ 

44,088 
_________ 

111,006 
_________ 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

1,658,314 
142,829 
431,762 
103,970 
56,509 
_________ 

244,848 
9,223 
2,593,789 
4,781 
- 
_________ 

2,393,384 
_________ 

2,852,641 
_________ 

Key management personnel compensation 

Key management personnel are those persons having authority and responsibility for planning, directing and 
controlling the activities of the Group, including the Directors of the Company. 

Salary 
Share based payment expense 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

560,040 
- 
_________ 

121,421 
2,577,826 
_________ 

560,040 
_________ 

2,699,247 
_________ 

The average number of employees (including Directors) in the Group in the period was 13 (2020 – 8). 

51 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

8 

Segment information 

The  Group  has  one  division  being  the  development  of  prognostic  and  diagnostic  tests  for  kidney  transplant 
patients.  

9 

Finance expense 

Finance expense 

Interest expense on Convertible Loan Note 
Loan interest 

Total finance expense 

10  Tax expense 

Current tax expense 
Current tax on loss for the period 

Total current tax 

Deferred tax asset 
On losses generated in the period 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

- 
- 
_________ 

68,807 
906 
_________ 

- 
_________ 

69,713 
_________ 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

- 
_________ 

- 
_________ 

- 

- 

- 
_________ 

- 
_________ 

- 
_________ 

- 
_________ 

52 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

10  Tax expense (continued) 

The reasons for the difference between the actual tax charge for the year and the standard rate of corporation 
tax in the United Kingdom applied to profits for the year are as follows: 

Loss for the period 

Tax using the Company’s domestic tax rate of 19%  
Expenses not deductible for tax purposes 
Accelerated capital allowances 
Unrecognised deferred tax assets  
Different tax rates applied in overseas jurisdictions 

Total tax expense 

Year to 
31 December 
2021 
US$ 

Period 
22 April to 
31 December 
2020 
US$ 

(8,329,829) 
_________ 

(4,735,007) 
_________ 

(1,582,668) 
58,475 
(143,521) 
2,327,906 
(660,192) 
_________ 

(899,651) 
41,987 
- 
931,344 
(73,680) 
_________ 

- 
_________ 

- 
_________ 

The unrecognised deferred tax relates to two elements: the unrecognised deferred tax arising on share-based 
payments  of  US$198,786  (2020  -  US$583,081)  and  unrecognised  deferred  tax  on  taxable  losses  of 
US$2,129,120  (2020  -  US$348,263).  Total  taxable  losses  carried  forward  are  US$9,256,260  (2020  -
US$1,490,633).  No deferred tax asset is recognised for these losses due to early stage in the development of 
the Group’s activities. The losses do not expire but can only be used against trading profits from the same trade. 

11  Earnings per share 

Numerator 

Year to 
31 December 
2021 
Total 
US$ 

Period 
22 April to 
31 December 
2020 
Total 
US$ 

Loss for the period used in basic EPS 

(8,329,829) 

(4,735,007) 

Denominator 

Weighted average number of ordinary shares used in basic EPS 

141,747,816 

86,728,156 

Resulting loss per share 

(US$0.059) 

(US$0.0546) 

The Company has one category of dilutive potential ordinary share, being share options (see note 19). The 
potential shares were not dilutive in the period as the Group made a loss per share in line with IAS 33.   

53 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

12  Tangible assets 

Group 

Cost or valuation 

At 22 April 2020 
Additions 
Acquired business assets (Note 23) 
Foreign exchange movements 

At 31 December 2020 
Additions 
Foreign exchange movements 

At 31 December 2021 

Accumulated depreciation and impairment 

At 22 April 2020 
Depreciation 
Foreign exchange movements 

At 31 December 2020 
Depreciation 
Foreign exchange movements 

At 31 December 2021 

Net book value 
At 31 December 2021 

At 31 December 2020 

Plant & 
machinery 
US$ 

Total 
US$ 

25,851 
531,484 
36,565 
_________ 

593,900 
617,940 
(5,826) 
_________ 

25,851 
531,484 
36,565 
_________ 

593,900 
617,940 
(5,826) 
_________ 

1,206,014 
_________ 

1,206,014 
_________ 

(123,242) 
(6,616) 
_________ 

(123,242) 
(6,616) 
_________ 

(129,858) 
(295,178) 
4,758 
_________ 

(129,858) 
(295,178) 
4,758 
_________ 

(420,278) 
_________ 

(420,278) 
_________ 

785,736 
_________ 

785,736 
_________ 

464,042 
_________ 

464,042 
_________ 

54 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

12  Tangible assets (continued) 

Company 

Cost or valuation 

At 22 April 2020 
Additions 
Acquired business assets (Note 23) 
Foreign exchange movements 

At 31 December 2020 
Additions 
Foreign exchange movements 

At 31 December 2021 

Accumulated depreciation and impairment 

At 22 April 2020 
Depreciation 
Foreign exchange movements 

At 31 December 2020 
Depreciation 
Foreign exchange movements 

At 31 December 2021 

Net book value 
At 31 December 2021 

At 31 December 2020 

Plant & 
machinery 
US$ 

Total 
US$ 

- 
531,484 
36,565 
_________ 

568,049 
- 
(5,826) 
_________ 

- 
531,484 
36,565 
_________ 

568,049 
- 
(5,826) 
_________ 

562,223 
_________ 

562,223 
_________ 

(119,630) 
(6,616) 
_________ 

(119,630) 
(6,616) 
_________ 

(126,246) 
(190,863) 
4,758 
_________ 

(126,246) 
(190,863) 
4,758 
_________ 

(312,351) 
_________ 

(312,351) 
_________ 

249,872 
_________ 

249,872 
_________ 

441,803 
_________ 

441,803 
_________ 

55 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

13 

Intangible assets 

Group 

Cost 

At 22 April 2020 
Additions  
Acquired business assets (Note 23) 
Foreign exchange movements 

At 31 December 2020 
Additions  
Foreign exchange movements 

At 31 December 2021 

Accumulated amortisation and impairment  

At 22 April 2020 
Amortisation charge  
Foreign exchange movements 

At 31 December 2020 
Amortisation charge  
Foreign exchange movements 

At 31 December 2021 

Net book value 
At 31 December 2021 

At 31 December 2020 

License and 
patents 
US$ 

Total 

US$ 

234,095 
1,468,516 
136,584 
_________ 

1,839,195 
397,919 
(17,663) 
_________ 

234,095 
1,468,516 
136,584 
_________ 

1,839,195 
397,919 
(17,663) 
_________ 

2,219,451 
_________ 

2,219,451 
_________ 

(68,993) 
(2,778) 
_________ 

(68,993) 
(2,778) 
_________ 

(71,771) 
(142,578) 
2,521 
_________ 

(71,771) 
(142,578) 
2,521 
_________ 

(211,828) 
_________ 

(211,828) 
_________ 

2,007,623 
_________ 

2,007,623 
_________ 

1,767,424 
_________ 

1,767,424 
_________ 

56 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

13 

Intangible assets (continued) 

Company 

Cost 

At 22 April 2020 
Additions  
Acquired business assets (Note 23) 
Foreign currency movements 

At 31 December 2020 
Additions  
Foreign currency movements 

At 31 December 2021 

Accumulated amortisation and impairment  

At 22 April 2020 
Amortisation charge  
Foreign exchange movements 

At 31 December 2020 
Amortisation charge  
Foreign exchange movements 

At 31 December 2021 

Net book value 
At 31 December 2021 

At 31 December 2020 

License and 
patents 
US$ 

Total 

US$ 

117,061 
1,468,516 
136,584 
_________ 

1,722,161 
54,337 
(17,663) 
_________ 

117,061 
1,468,516 
136,584 
_________ 

1,722,161 
54,337 
(17,663) 
_________ 

1,758,835 
_________ 

1,758,835 
_________ 

(68,274) 
(2,778) 
_________ 

(68,274) 
(2,778) 
_________ 

(71,052) 
(123,973) 
2,521 
_________ 

(71,052) 
(123,973) 
2,521 
_________ 

(192,504) 
_________ 

(192,504) 
_________ 

1,566,331 
_________ 

1,566,331 
_________ 

1,651,109 
_________ 

1,651,109 
_________ 

The licence was acquired from Renalytix AI Plc on 4 May pursuant to a purchase of business assets (see Note 
23).  This license in turn was granted to Renaltix AI Plc by the Icahn School of Medicine at Mount Sinai for rights 
to intellectual property and data to support the FractalDx families of diagnostic assays. In addition amounts are 
spent on the prosecution and protection of patent applications. 

The Group has tested the carrying value for impairment at 31 December 2021. The recoverable amount was 
assessed in the basis of value in use. The assessed value exceeded the carrying value and no impairment loss 
was recognised. The key assumptions in the calculation to assess value in use are future revenues and costs 
and the ability to generate future cash flows. Recent working capital projections approved by the Board were 
used as well as forecasts for a further four years, followed by an extrapolation of expected cash flows and the 
calculation of a terminal value.  

57 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

14  Subsidiary 

The principal subsidiary of Verici Dx plc, which has been included in these consolidated financial statements at 
a cost of US$10, is as follows: 

Name 

Country of incorporation and  
principal place of business 

Proportion of ownership 
interest at 31 December 
2021 

Verici Dx Inc 

United States of America 

100% 

15  Trade and other receivables 

Prepayments 
Other debtors 
Amount due from wholly owned 
subsidiary undertaking 

16  Trade and other payables 

Trade payables 
Accruals  
Loan 

Total financial liabilities classified as 
financial liabilities measured at 
amortised cost 

Other payables - tax and social 
security payments 

Group 
2021 
US$ 

406,191 
249,656 

Company 
2021 
US$ 

100,537 
17,243 

Group 
2020 
US$ 

202,546 
120,678 

Company 
2020 
US$ 

115,830 
120,678 

- 
_________ 

8,226,284 
_________ 

- 
_________ 

1,027,350 
_________ 

655,847 
_________ 

8,344,064 
_________ 

323,224 
_________ 

1,263,856 
_________ 

Group 
2021 
US$ 

159,534 
1,644,575 
- 
_________ 

Company 
2021 
US$ 

16,112 
165,017 
- 
_________ 

Group 
2020 
US$ 

394,331 
210,953 
73,548 
_________ 

Company 
2020 
US$ 

44,912 
69,519 
73,548 
_________ 

1,804,109 

181,129 

678,832 

187,979 

- 
_________ 

- 
_________ 

3,058 
_________ 

- 
_________ 

Total trade and other payables 

1,804,109 
_________ 

181,129 
_________ 

681,890 
_________ 

187,979 
_________ 

The  carrying  value  of  trade  and  other  payables  classified  as  financial  liabilities  measured  at  amortised  cost 
approximates fair value. 

The loan was interest bearing at 4% and repayable by monthly instalment with the last instalment paid in March 
2021. 

58 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

17  Share capital 

Ordinary shares of £1 each 
On incorporation 

Ordinary shares of £0.001 each 
Sub-division of existing shares into 1,000 ordinary shares  
Issue of new shares  
Issue of shares on conversion of Convertible Loan Notes 
Placing and offer of shares on admission to AIM 

At 31 December 2020 and 2021 

Issued and fully paid 

2021 
Number 

2021 
US$ 

1 
__________ 

1 
__________ 

1,000 
59,415,135 
9,831,681 
72,500,000 
__________ 

1 
74,864 
12,771 
93,978 
__________ 

141,747,816 
__________ 

181,614 
__________ 

On 7 July 2020 the entire issued share capital of the Company was sub divided to create 1,000 ordinary shares of 
£0.001 each and 59,415,135 ordinary shares of £0.001 each were allotted pursuant to a dividend in specie by the then 
parent company, Renalytix AI Plc.  Those 59,416,135 shares were then immediately reclassified as 59,416,134 A 
shares and one Golden Share and all A shares and the Golden Share converted into ordinary shares at the time of the 
Company’s admission to AIM on 3 November 2020. 

On 28 October 2020 pursuant to the conversion of the Convertible Loan Notes is issue at that time of $2,500,000, a 
further 9,831,681 new ordinary shares were issued. 

On 3 November 2020 pursuant to the Company’s shares being admitted to AIM, a market operated by the London 
Stock Exchange, 72,500,000 new ordinary shares were issued at an issue price of £0.20 per share raising gross 
proceeds of US$18,795,500 (£14,500,000).  

18  Reserves 

The following describes the nature and purpose of each reserve within equity: 

Reserve 

Description and purpose 

Share premium 

Amount subscribed for share capital in excess of nominal value. 

Foreign exchange reserve 

Gains/losses  arising  on  retranslating  the  net  assets  of  parent 
company operations into US dollars. 

Convertible debt option reserve 

Amount of proceeds on issue of convertible debt relating to the 
equity  component  (i.e.  option  to  convert  the  debt  into  share 
capital). 

Retained earnings 

All other net gains and losses and transactions with owners (e.g. 
dividends) not recognised elsewhere. 

59 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

19  Share-based payment  

On 28 October 2020, the Board adopted the Share Option Plan to incentivise certain of the Group’s employees and 
Directors. The Share Option Plan provides for the grant of both EMI Options and non-tax favoured options. Options 
granted under the Share Option Plan are subject to exercise conditions as summarised below. 

The  Share  Option  Plan  has  a  non-employee  sub-plan  for  the  grant  of  Options  to  the  Company’s  advisors, 
consultants, non-executive directors, and entities providing, through an individual, such advisory, consultancy, 
or office holder services and a US sub-plan for the grant of Options to eligible participants in the Share Option 
Plan and the Non-Employee Sub-Plan who are US residents and US taxpayers. 

With the exception of options over 10,631,086 shares, which vested immediately on grant in 2020, the options 
vest equally over twelve quarters from the grant date.  If options remain unexercised after the date one day 
before the tenth anniversary of grant such options expire. The Options are subject to exercise conditions such 
that they shall, subject to certain exceptions, vest in equal quarterly instalments over the three years immediately 
following  the  date  of  grant,  which  vesting  shall  accelerate  in  full  in  the  event  of  a  change  of  control  of  the 
Company. 

Outstanding at 22 April 2020 
Granted during the period 
Exercised during the period 

Weighted 
average 
exercise 
price (p) 

- 
32 
20 
_________ 

Number 

- 
14,574,782 
(10,631,086) 
_________ 

Outstanding at 31 December 2020 

32 

3,943,696 

Granted during the year 

Exercisable at 31 December 2020 

62.61 
_________ 
26.03 
_________ 

990,000 
_________ 
4,933,696 
_________ 

_________ 

_________ 

The  exercise  price  of  options  outstanding  at  31  December  2021  ranged  between 20p  and 69.5p  and  their 
weighted average contractual life was 3.85 years.   

The weighted average fair value of each option granted during the year was 26.46p. 

The fair value of each share option granted has been estimated using a Black-Scholes model and ranges from 
10p to 23p. The inputs into the model are a share prices of 20p, 40p,45.5p, 50p and 69.5p and exercise prices 
of 20p, 40p,45.5p, 50p and 69.5p and expected volatility of 48.5%, no expected dividend yield, contractual life 
of  between  2.9  and  1.9  years  and  a  risk-free  interest  rate  of  0.34%.  As  of  31  December  2021,  none  of  the 
granted stock options have been exercised. 

The Group recognised total expenses of $740,829 (2020 - $2,794,625) within administrative expenses relating 
to equity-settled share-based payment transactions during the period. 

60 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

20  Related party transactions 

As noted in Note 23, on 4 May 2020 the Company entered into an Asset Purchase Agreement with Renalytix 
AI Plc.  Renalytix Plc is a shareholder on the Company and James McCullough, a Director of the Company, is 
also a Director and CEO of Renalytix Plc.  

In connection with this transaction the Company also entered into a Convertible Loan Agreement to both fund 
this transaction and also provide working capital until the admission of the shares onto AIM.  The total amount 
advanced  under  the  Convertible  Loan  Note  at  the  time  of  its  redemption  in  full  into  ordinary  shares  of  the 
Company was $2,500,000. 

In the year to 31 December 2021 an amount of US$351,863 was paid to Renalytix Plc as full reimbursement 
for expenses incurred on behalf of the Company.  As of 31 December 2021 the amount owed to Renalytix Plc 
was US$22,312. 

21  Loans and borrowings 

Issue of Convertible Loan Notes  
Amount classified as equity 
Accreted interest 
Converted into ordinary shares 

Group 
2021 
US$ 

- 
- 
- 
- 
_________ 

Company 
2021 
US$ 

- 
- 
- 
- 
_________ 

Group 
2020 
US$ 

Company 
2020 
US$ 

2,500,000 
(165,138) 
68,807 
(2,403,669) 
_________ 

2,500,000 
(165,138) 
68,807 
(2,403,669) 
_________ 

As at 31 December 2020 

- 
_________ 

- 
_________ 

- 
_________ 

- 
_________ 

The initial Convertible Loan Note Instrument of US$2,000,000 (“the Note”) was issued on 4 May 2020.  It had a 
nil % coupon, which has been accounted for at fair value at inception and the difference recognised as a capital 
contribution.  As the conversion feature resulted in the conversion of a fixed amount of stated principal into a 
variable number of shares, it did not satisfy the ‘fixed for fixed’ criterion and, therefore, it was classified as a 
financial  liability.  The  fair  value  of  the  financial  liability  was  calculated  using  a  market  interest  rate  for  an 
equivalent instrument without a conversion option. The discount rate applied was 9%.  

22  Events after the reporting date 

 On  11  March  2022  the  Company  closed  a  fundraising  for  GBP10.0m  before  expenses  by  the  issue  of 
28,571,429 new shares. 

61 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

Notes forming part of the consolidated financial statements 
for the year ended 31 December 2021 (continued) 

23  Acquisition of business assets 

On 4 May 2020 the Company entered into an Asset Purchase Agreement with Renalytix AI Plc. The fair value 
of the assets acquired, and the consideration paid were as follows: 

Assets acquired 
Licence 
Plant & Machinery 

Contractual repayment amount of Convertible Loan Note Instrument at inception 

Consideration - repayment liability 

US$ 

1,468,516 
531,484 
_________ 

2,000,000 
_________ 

2,000,000 
_________ 

2,000,000 
_________ 

Subsequent to the acquisition of the assets, further Convertible Loan Notes were issued by Renalytix AI Plc to 
provide working capital to the Company prior to its admission to the London Stock Exchange on 3 November 
2020.  The Convertible Loan Note was non-interest bearing.   

On 28 October 2020 the total Convertible Loan Note of $2,500,000 was redeemed and converted into 9,831,681 
ordinary shares. 

Non-cash transaction 

This transaction, together with the subsequent funding of working capital of the Company by further issuance 
of Convertible Loan Notes on the same terms until Admission to the AIM on 3 November 2020 represented the 
major non-cash transaction in the year. 

62 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

NOTICE OF ANNUAL GENERAL MEETING 

NOTICE IS HEREBY GIVEN that the Annual General Meeting (Meeting) of Verici Dx plc (Company) will be held at 
Avon House, 19 Stanwell Road, Penarth, Cardiff CF64 2EZ on 27 June 2022 2022 at 3 p.m.  

Introduction 

The Company has decided to hold this year’s AGM as a physical meeting of the shareholders of the Company.  
To submit any questions in advance please contact Walbrook PR via email at verici@walbrookpr.com or call +44 
(0)20 7933 8780.   

Shareholders wishing to vote on any of the matters of business are strongly advised to appoint the Chairman of the 
Meeting as their proxy. Shareholders must appoint a proxy through completion of a form of proxy. Shareholders can 
appoint a proxy by logging on to www.signalshares.com and following the instructions or lodging a proxy appointment 
by using the CREST Proxy Voting Service or requesting a hard copy proxy form by contacting our Registrars, Link 
Group, on 0371 664 0300 from the UK (Calls are charged at the standard geographic rate and will vary by provider. 
Calls outside the United Kingdom will be charged at the applicable international rate) and returning it to the address 
shown on the form.  

Annual General Meeting 

The Annual General Meeting is being held to consider the following resolutions, of which resolutions 1 to 4 will be 
proposed as ordinary resolutions and resolution 5 as a special resolution:  

Ordinary Resolutions 

1. 

2. 
3. 

4. 

for 

the  statement  of  accounts 

the  year  ended  31  December  2021  

To  receive  and  adopt 
together with the reports of the Directors and the auditors thereon. 
To re-elect Dr Lorenzo Gallon, who retires by rotation, as a Director. 
To  re-appoint  Messrs  Crowe  U.K.  LLP  as  auditors  to  act  as  such  until  the  conclusion  of  the 
next General Meeting of the Company at which the requirements of section 437 of the Companies Act 2006 
are complied with and to authorise the Directors of the Company to fix their remuneration. 
That 
the  Directors  be  and  are  hereby  
for  any  existing  such  authority, 
generally  and  unconditionally  authorised  pursuant  to  section  551  of  the  Companies  Act  2006  
(the  “2006  Act”)  to  allot  equity  securities  (as  defined  in  section  560  of  the  2006  Act)  in  the  
 capital of the Company: 
up to a maximum nominal amount of £16,000 (in pursuance of the exercise of outstanding share options and 

in  substitution 

(i) 
other potential shares granted by the Company but for no other purpose); 
(ii) 
(i) above) representing approximately 25% of the Company’s Issued Share Capital, 

up to an aggregate nominal amount of £42,579.81 (in addition to the authorities conferred in sub-paragraphs 

such authorities (unless previously renewed, revoked or varied) to expire at the conclusion of the next Annual General 
Meeting  of  the  Company  to  be  held  in  2023,  save  that  the  Company  may,  before  such  expiry,  make  an  offer  or 
agreement which would or might require equity securities (as defined in section 560 of the 2006 Act) to be allotted 
after such expiry and the directors may allot such equity securities in pursuance of such an offer or agreement as if 
the authority conferred hereby had not expired. 

63 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
     
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

NOTICE OF ANNUAL GENERAL MEETING (continued) 

Special Resolution 

5. 

(i) 

(ii) 

(iii) 

to 

the  Directors  be  given 

the  passing  of  Resolution  4  above 

the  general  
That,  subject 
power  to  allot  equity  securities  (as  defined  in  section  560  of  the  2006  Act)  pursuant  to  the  
authority  conferred  by  Resolution  4  above  as 
the  2006  Act  did  not  
apply to any such allotments provided that this power shall be limited to: 
the  allotment  of  equity  securities  on 
Company; 
the  allotment  of  equity  securities  (otherwise 
for  
cash  in  connection  with  any  rights  issue  or  pre-emptive  offer  in  favour  of  holders  of  equity  
securities generally; and 
the  allotment 
securities 
for 
approximately 25% of the Company’s Issued Share Capital 

than  pursuant 
to  an  aggregate  nominal  amount  of  £42,579.81 

(ii)  above)  of  equity  
representing  

the  share  options  granted  by 

to  sub-paragraphs  (i)  above) 

(otherwise 
cash  up 

if  section  561(1)  of 

to  sub-paragraphs 

the  exercise  of 

than  pursuant 

(i)  and 

the  

provided that such power (unless previously renewed, revoked or varied) shall expire at the conclusion of the Annual 
General Meeting of the Company to be held in 2023, save that the Company may, before such power expires, make 
an offer or enter into an agreement which would or might require equity securities to be allotted after such power 
expires and the Directors may allot equity securities in pursuance of any such offer or agreement notwithstanding 
that the power conferred by this resolution has expired. 

BY ORDER OF THE BOARD 

Salim Hamir  
Company Secretary 

Registered Office: 
Avon House 
19 Stanwell Road Penarth 
CF64 2EZ 

25 May 2022 

64 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Verici Dx plc 

NOTICE OF ANNUAL GENERAL MEETING (continued) 

Additional information 

Notes: 

Every eligible shareholder is entitled to appoint a proxy to exercise all or any of their rights to attend and to 

1. 
speak and vote on their behalf at the AGM.  
Pursuant to Regulation 41 of the Uncertificated Securities Regulations 2001, only those members registered 
2.  
on the Company’s register of members at close of business on 23 May 2022, or, if this general meeting is adjourned, 
members  on  the  Company’s  register  of  members  not  later  than  48  hours  before  the  fixed  time  for  the  adjourned 
meeting, shall be entitled to attend and vote at the General Meeting.   
If you are a Shareholder of the Company at the time set out in note 2 above, you are entitled to appoint a 
3.  
proxy to exercise all or any of your rights to attend, speak and vote at the meeting. A proxy does not need to be a 
shareholder of the Company but must attend the meeting to represent you. You can only appoint a proxy using the 
procedures set out in these notes and the notes to the proxy form.  
4. 
In the case of joint holders, where more than one of the joint holders purports to appoint a proxy, only the 
appointment submitted by the most senior holder will be accepted. Seniority is determined by the order in which the 
names of the joint holders appear in the Company’s register of members in respect of the joint holding (the first-
named being the most senior). 
5. 
A vote withheld is not a vote in law, which means that the vote will not be counted in the calculation of votes 
for or against the resolution. If no voting indication is given, your proxy will vote or abstain from voting at his or her 
discretion. Your proxy will vote (or abstain from voting) as he or she thinks fit in relation to any other matter which is 
put before the Meeting. 
6.  
You may appoint more than one proxy provided each proxy is appointed to exercise the rights attached to a 
different share or shares held by that shareholder. To appoint more than one proxy, please contact the Registrars, 
Link Group at  shareholderenquiries@linkgroup.co.uk or on Tel: 0371 664 0300. Calls outside the United Kingdom 
will  be  charged  at  the  applicable  international  rate.  Lines  are  open  between  09:00  –  17:30,  Monday  to  Friday 
excluding public holidays in England and Wales. You will need to state clearly on each proxy form the number of 
shares in relation to which the proxy is appointed. When two or more valid but differing appointments of proxy are 
received for the same meeting, the one which is last validly delivered or received (regardless of its date or the date 
of its execution) shall be treated as replacing and revoking the other or others as regards that share.  If the Company 
is unable to determine which appointment was last validly delivered or received, none of them shall be treated as 
valid in respect of that share.  
You  will  not  receive  a  hard  copy  form  of  proxy  with  this  document.  Instead,  you  will  be  able  to  vote 
7. 
electronically using the link www.signalshares.com. You will need to log into your Signal Shares account, or register 
if  you  have  not  previously  done  so.  To  register  you  will  need  your  Investor  Code,  this  is  detailed  on  your  share 
certificate or available from our Registrar, Link Group. Votes submitted electronically must be submitted by no later 
than 3pm on 23 June 2022. 
8. 
the  Registrars,  Link  Group  at 
shareholderenquiries@linkgroup.co.uk or on Tel: 0371 664 0300. Calls are charged at the standard geographic rate 
and will vary by provider. Calls outside the United Kingdom will be charged at the applicable international rate. Line 
are open between 09:00 - 17:30, Monday to Friday excluding public holidays in England and Wales. 
If you return more than one proxy appointment, either by paper or electronic communication, the appointment 
9. 
received last by the Registrar before the latest time for the receipt of proxies will take precedence. You are advised 
to read the terms and conditions of use carefully. Electronic communication facilities are open to all shareholders and 
those who use them will not be disadvantaged. 
CREST members who wish to appoint a proxy or proxies through the CREST electronic proxy appointment 
10. 
service may do so for the Meeting (and any adjournment of the Meeting) by using the procedures described in the 
CREST  Manual  (available  from  www.euroclear.com/site/public/EUI).  CREST  Personal  Members  or  other  CREST 
sponsored members, and those CREST members who have appointed a service provider(s), should refer to their 
CREST sponsor or voting service provider(s), who will be able to take the appropriate action on their behalf. 

You  may  request  a  hard  copy 

form  of  proxy  directly 

from 

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NOTICE OF ANNUAL GENERAL MEETING (continued) 

11. 
In order for a proxy appointment or instruction made by means of CREST to be valid, the appropriate CREST 
message (a ‘CREST Proxy Instruction’) must be properly authenticated in accordance with Euroclear UK & Ireland 
Limited’s specifications and must contain the information required for such instructions, as described in the CREST 
Manual. The message must be transmitted so as to be received by the issuer’s agent (ID RA10) by 3 p.m.23 June 
2022 , or, in the event of an adjourned of the Meeting, 48 hours before the adjourned meeting. For this purpose, the 
time of receipt will be taken to mean the time (as determined by the timestamp applied to the message by the CREST 
application host) from which the issuer’s agent is able to retrieve the message by enquiry to CREST in the manner 
prescribed by CREST. After this time, any change of instructions to proxies appointed through CREST should be 
communicated to the appointee through other means. 
12. 
CREST members and, where applicable, their CREST sponsors or voting service providers should note that 
Euroclear UK & Ireland Limited does not make available special procedures in CREST for any particular message. 
Normal system timings and limitations will, therefore, apply in relation to the input of CREST Proxy Instructions. It is 
the responsibility of the CREST member concerned to take (or, if the CREST member is a CREST personal member, 
or sponsored member, or has appointed a voting service provider(s), to procure that his CREST sponsor or voting 
service provider(s) take(s)) such action as shall be necessary to ensure that a message is transmitted by means of 
the CREST system by any particular time. In this connection, CREST members and, where applicable, their CREST 
sponsors or voting system providers are referred, in particular, to those sections of the CREST Manual concerning 
practical limitations of the CREST system and timings. The Company may treat as invalid a CREST Proxy Instruction 
in the circumstances set out in Regulation 35(5)(a) of the Uncertificated Securities Regulations 2001. 
To change your proxy instructions simply submit a new proxy appointment using the methods set out above. 
13. 
Note that the cut-off time for receipt of proxy appointments (see above) also apply in relation to amended instructions; 
any  amended  proxy  appointment  received  after  the  relevant  cut-off  time  will  be  disregarded.  Where  you  have 
appointed a proxy using the hard-copy proxy form and would like to change the instructions using another hard-copy 
proxy form, please contact Link Group at the address noted in note 6 above.  
14. 
In order to revoke a proxy instruction you will need to inform the Company by contacting Link Group on 0371 
664 0300. In the case of a member which is a company, the revocation notice must be executed under its common 
seal or signed on its behalf by an officer of the company or an attorney for the company. Any power of attorney or 
any other authority under which the revocation notice is signed (or a duly certified copy of such power or authority) 
must be included with the revocation notice. The revocation notice must be received by Link Group no later than 3 
p.m. on 23 June 2022. If you attempt to revoke your proxy appointment but the revocation is received after the time 
specified then, subject to the paragraph directly below, your proxy appointment will remain valid. 
15. 
Appointment of a proxy does not preclude you from attending the general meeting and voting in person. If 
you have appointed a proxy and attend the general meeting in person, your proxy appointment will automatically be 
terminated.  
16. 
A corporation which is a member can appoint one or more corporate representatives who may exercise, on 
its behalf, all its powers as a member provided that no more than one corporate representative exercises power over 
the same share. 
Voting on the resolution will be conducted by way of a poll vote. 
17. 
18. 
As at the close of business on the day immediately before the date of this notice of general meeting, the 
Company’s  issued  share  capital  comprised  170,319,245  ordinary  shares  of  nominal  value  0.1  pence  each.  Each 
ordinary share carries the right to one vote at a general meeting of the Company and, therefore, the total number of 
voting rights in the Company as at close of business, on the day immediately before the date of this notice of general 
meeting is 170,319,245. 
19.  
Under Section 527 of the Companies Act 2006, shareholders meeting the threshold requirements set out in 
that section have the right to require the Company to publish on a website a statement setting out any matter relating 
to: (i) the audit of the Company’s financial statements (including the Auditor’s Report and the conduct of the audit) 
that are to be laid before the Meeting; or (ii) any circumstances connected with an auditor of the Company ceasing 
to hold office since the previous meeting at which annual financial statements and reports were laid in accordance 
with Section 437 of the Companies Act 2006 (in each case) that the shareholders propose to raise at the relevant 
meeting.  The  Company  may  not  require  the  shareholders  requesting  any  such  website  publication  to  pay  its 
expenses in complying with Sections 527 or 528 of the Companies Act 2006. Where the Company is required to 
place a statement on a website under Section 527 of the Companies Act 2006, it must forward the statement to the 
Company’s auditor not later than the time when it makes the statement available on the website. The business which 
may be dealt with at the Meeting for the relevant financial year includes any statement that the Company has been 
required under Section 527 of the Companies Act 2006 to publish on a website. 

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NOTICE OF ANNUAL GENERAL MEETING (continued) 

20. 
Any shareholder attending the Meeting has the right to ask questions [and shareholders are reminded to 
submit questions in advance of the Meeting, before 12 p.m. on 24 June 2022 by contacting Walbrook PR via email 
at  verici@walbrookpr.com  or  call  +44  (0)20  7933  8780.]    The  Company  must  cause  to  be  answered  any  such 
question relating to the business being dealt with at the Meeting but no such answer need be given if: (a) to do so 
would interfere unduly with the preparation for the Meeting or involve the disclosure of confidential information; (b) 
the  
answer has already been given on a website in the form of an answer to a question; or (c) it is undesirable in the 
interests of the Company or the good order of the Meeting that the question be answered. 
21.  
The following documents are available for inspection during normal business hours at the registered office 
of the Company on any business day from the date of this Notice until the time of the Meeting and may also be 
inspected  at  the  Meeting  venue,  as  specified  in  this  Notice,  from  10.00  a.m.  on  the  day  of  the  Meeting  until  the 
conclusion of the Meeting: 

- copies of the Directors’ letters of appointment or service contracts. 
22. 
You may not use any electronic address (within the meaning of Section 333(4) of the Companies Act 2006) 
provided  in  either  this  Notice  or  any  related  documents  (including  the  form  of  proxy)  to  communicate  with  the 
Company for any purposes other than those expressly stated. 

A copy of this Notice, and other information required by Section 311A of the Companies Act 2006, can be found on 
the Company’s website at www.vericidx.com 

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Perivan   263540

Verici Dx 
Avon House
19 Stanwell Road
Penarth
Cardiff, CF64 2EZ

vericidx.com