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Alliance Pharma

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FY2013 Annual Report · Alliance Pharma
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ALLIANCE PHARMA plc Annual Report and
Accounts for the year ended 31 December 2013

2013 Annual Report

Contents

Business Summary*

                                          Highlights     01

                               Our Business Model     02

                                                  Products     04

    International Commercial Presence     06

Report of the Directors

                                     Strategic Report     08

                                  Board of Directors     12

                           Senior Team Members     14

                           Corporate Governance     15

                       Directors’ Remuneration     16

                                          Other Matters     18

Financial Statements

               Independent Auditor’s Report     20
                   to the Members of Alliance
                                              Pharma plc

           Consolidated Income Statement     21

                    Consolidated Statement of         
                         Comprehensive Income     22

                 Consolidated Balance Sheet     23

                        Company Balance Sheet     24

                      Consolidated Statement of     25
                                   Changes in Equity

                             Company Statement of     26
                                      Changes in Equity

                   Consolidated and Company     27
                              Cash Flow Statements

        Notes to the Financial Statements     28

Supplementary Information*

                       Shareholder Information     61

                                 Five Year Summary     62

                                                   Advisors     63

*Unaudited information.

Alliance Pharma plc | Annual Report 2013

Alliance Pharma 
plc is an AIM 
listed speciality
pharmaceutical
company

Alliance has a strong track record of acquiring the 

rights to established niche products and owns or

licences the rights to more than 60 pharmaceutical

products and continues to explore opportunities to

expand the range. The group commenced trading in

1998 and has since grown to an annual turnover of

£46m. Alliance has its headquarters in the UK at

Chippenham, Wiltshire.

Highlights

Business Summary

Key
Numbers

Revenue

Profit 
before tax

44.9

45.5

12.0

10.8

£45.5m

£12.0m

2013
Key Facts

2012

2013 

2012

2013 

Dividend

EPS – basic

0.605

0.55

3.82

3.61

0.908p

3.82p

0.303

0.275

2012

2013 

Interim

Final

2012

2013 

Three acquisitions of
products since June 2013
with annualised gross
margin of £2.6m

France and Germany both
now trading profitably 

Hydromol continues 
good growth, achieving
year on year revenue
growth of 12%

New packaging 
equipment for Ashton &
Parsons Infants’ Powders
now operational, with
production volumes
ramping-up

Full year dividend up 
10% to 0.908p per share
(2012: 0.825p)

Low gearing with Debt to
EBITDA ratio of 1.6 times*

Operating profit 29% 
of sales

*Including proforma EBITDA of acquisitions. 

Alliance Pharma plc | Annual Report 2013

01

Our Business Model

Strategy
Alliance is a speciality pharma company pursuing a buy and build strategy. It expands its portfolio by
acquisition or inward licensing. It does not engage in R&D, except for minor line extensions.

The acquired products are ones whose
market position has been established by
their originators. Where necessary,
Alliance ensures the product’s viability by
regulatory and technical initiatives so that
the established franchise can be relied
upon to provide sustainable cash-flow into
the foreseeable future. Acquired products
are assessed for their potential to respond
to promotional investment. If promotion
would produce an economic return, then it
is implemented via Alliance’s specialised
sales and marketing operation. For many
products, however, having had their

Longevity of Brands

market positions established many years
ago, the most economic strategy is to
maintain them for their cash generation.

servicing and the operational needs 
of the business, is then available for
dividend payments.

Corporate growth is further enhanced by
licensing in and marketing products that
have been developed by other companies’
R&D activities.

Acquisitions of products are typically
financed by a combination of bank debt
and equity in a ratio that optimises
earnings per share, whilst maintaining
acceptable levels of gearing. Surplus cash
generated, after providing for debt

Labour and capital intensive activities,
such as manufacturing, warehousing and
distribution, are outsourced so that new
products may be quickly integrated into
the Alliance portfolio with minimal
increase in overheads. Outsourcing
enables management to concentrate on
key decisions and act quickly to take
advantage of opportunities as they arise.

PRODUCT

Hydromol

Toxicology Product

Nu-Seals

Syntometrine

Buccastem

Forceval

Timodine

Syntocinon

Paludrine

Vitamin E

ANNUAL REVENUE 2013

LAUNCH

£5.3m

£3.9m

£3.0m

£2.8m

£2.3m

£1.9m

£1.6m

£1.6m

£1.5m

£1.5m

1987

1991

1978

1956

1987

1970

1972

1956

1972

1989

Risk Reduction 
Through Diversity
Any potential risk is spread 
across a portfolio of over 
60 products, the largest 
representing just over 
10% of Alliance’s sales.*

Deltacortril 1.3%

Buccastem 4.6%

Forceval 3.9%

Anti malarials 4.3%

Vitamin E 3.1%

Nu-Seals 6.2%

Symmetrel 2.3%

Other Secondary care 2.4%

Opus stoma products 8.0%

Risk Reduction Through Diversity

AVERAGE 
AGE 38
YEARS

Hydromol 10.8%

Naseptin 2.6%

Syntometrine 5.9%

Other Dermatology 7.3%

Other 37.3% (35 products)

*Proforma 2013 Revenue. 

02 Alliance Pharma plc | Annual Report 2013

Business Summary

Product Acquisition Strategy
Product life-cycle: Alliance’s bedrock products are usually at least 10 years post patent expiry with a
stable sales history and a low volume that limits direct competition.

Patent protection
Patent protection

High price/short life
High price/short life

Big Pharma
Big Pharma

Heavy marketing
Heavy marketing

VoVolulumeme r risisk k ++++
Volume risk ++

H
S
A
C

Development Biotechs

Development risk +++

26

60

26 deals
in 16 years

Over 60
products

Building global
operation

2012
£12.4m
2 deals

2013
£9.4m
2 deals

Higher volume – generic
Higher volume – generic
competition
competition

Very price competitive
Very price competitive

Price risk ++
Price risk ++

Lower volume – typically
Lower volume – typically
no competition
no competition

I MT
T I M E

Limited or no
competition
10+ years out of
patent
Stable sales
Low risk

Actively
searching for
acquisitions

Alliance has a strong track
record of successful
acquisitions and has
considerable expertise in
target selection, contract
negotiation and integration 
of the products into its
operations. It has considerable
financial resources available
for future deals.

2010
£16.4m
1 deal

2009
£7.5m
1 deal

2011
£6.5m
3 deals

2001
£4.5m
2 deals

20
2002
£11
£11.1m
2 deals

1999
£2.1m
1 deal

2004
£9.7m
3 deals

Total Investment Since 1999

2008
£0.6m
1 deal

2007
£1.95m
1 deal

2006
£7.4m
5 deals

Alliance Pharma plc | Annual Report 2013

03

Products

Balanced Portfolio
The bedrock of non-promoted products provides considerable cash generation to support the growth
activities behind the Dermatology, Specialised Secondary Care and Consumer products. In this way a
healthy corporate operating profit of 29% of sales is maintained. 

15%

13%

8%

19%

Dermatology
A range of products for the 
remission of eczema and skin 
complaints.

Specialist
Secondary Care
A range of products used by 
hospitals.

Consumer
A range of products sold over
the counter.

International
Products where we hold 
international marketing 
authorisation where required.

45%

The bedrock: core portfolio of non-promoted products

Portfolio Profiles
Alliance has acquired products in a range of therapy areas; details on some of these are 
provided below:

Dermatology

Hydromol – an emollient range of creams,
bath additives and ointments to maintain
skin hydration and prevent exacerbations
of eczema.

Timodine – is used to treat inflamed skin
conditions, such as eczema and severe
nappy rash, particularly involving the
fungal infection Candida albicans.

Gelclair – an oral gel that helps to 
relieve the severe pain associated with oral
mucositis and other oral lesions 
that can occur with common cancer
treatments.

Opus stoma care products – a range 
of ancillary products such as barrier
creams, adhesive removers and absorbent
gels that make the wearing of stoma bags
more comfortable.

Specialist Secondary Care

Consumer

ImmuCyst – Immunotherapy for non-
muscle-invasive bladder cancer.

ImmuCyst is instilled into the bladder and
produces an intensive, local immune
response that destroys the tumour cells.

Ashton & Parsons – a well renowned
herbal product traditionally used in 
infants for the symptomatic relief of 
the pain and stomach upset associated
with teething.

Anbesol – to relieve the pain of mouth
ulcers, denture irritation and teething pain
in children.

Quinoderm – a dual action product for
acne, particularly in teenagers.

MolluDab – a proven treatment for
molluscum contagiosum, which is a
common and highly contagious viral
infection of the skin, particularly in 
school children.

Lypsyl – a classic brand of lip salve for
preventing cracked lips.

04 Alliance Pharma plc | Annual Report 2013

Business Summary

Hydromol

Alliance acquired Hydromol in 2006 from Ferndale Pharmaceuticals. Hydromol is promoted by a small
field force covering hospital and general practice. Sales have grown from £0.9m at the time of
acquisition to £5.3m in 2013.

£6m

£5m

£4m

£3m

£2m

£1m

Hydromol sales

Moving Annual
Total

9
0
-
n
a
J

9
0
-
y
a
M

9
0
-
p
e
S

0
1
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a
J

0
1
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y
a
M

0
1
-
p
e
S

1
1
-
n
a
J

1
1
-
y
a
M

1
1
-
p
e
S

2
1
-
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J

2
1
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M

2
1
-
p
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S

3
1
-
n
a
J

3
1
-
y
a
M

3
1
-
p
e
S

Opus stoma 
care products

Alliance acquired the 
Opus stoma care business 
in 2012. Turnover in 2013 
was £3.9m.

Ashton & Parsons Infants’ Powders

Ashton & Parsons Infants’ Powders were first produced in London in the late 1800s and soon became 
a popular treatment with parents for easing the symptoms of teething.

Alliance acquired the brand in 2011.
However, the specialist packaging
machinery required to produce the
traditional paper wrap originated in the
1950s, was unreliable and could not 
service the demand for the product. 
Alliance has re-designed the pack into a
modern sachet and, together with its
contract manufacturer, has invested in
modern high speed machinery.

Production levels are being ramped up in
2014 to meet the previously unsatisfied
demand. In the past, the brand’s popularity
was maintained through recommendation
by generations of grandparents and
parents. With increased product
availability, promotion of the brand, which

had been limited for decades because of
limited supply, now becomes possible. 
As technology has moved on, so have the
means of communication. The format of
support networks for new mums and dads
has changed and online social forums
have become the main ways of seeking
advice and support from a much wider
network. Responding to this shift, the 2014
Ashton and Parsons communication
program features a family album of mums
through the decades and aims to
encourage parents to spread the word
about Ashton and Parsons which, with full
product availability, no longer has to
remain ‘Mum’s little secret’ and parents
are now free to pass it on!

Alliance Pharma plc | Annual Report 2013

05

International Commercial Presence 

Direct Presence

Joint Venture

Local Partners

Local Partners:

Netherlands
Denmark
Finland
Sweden
Iceland
Spain
Portugal
Italy
Malta
Cyprus
Lebanon
Pakistan
Qatar
Oman
Egypt
Gabon

Niger
Burkina Faso
Madagascar
Kenya
South Africa
Namibia
Swaziland
Mauritius
Sri Lanka
Malaysia
Brunei
Singapore
Hong Kong
Australia
New Zealand
The Caribbean

Europe

Germany

As reported in 2012, Alliance has been
identifying an increasing number of
acquisition opportunities in Germany. 
In January 2014 we moved to a position 
of profitable trading by acquiring Irenat
from Bayer. Irenat is an established
endocrinology brand that is mainly used
for diagnosing and treating
hyperthyroidism.

France

In France where we achieved profitability 
via the anti-malarial business that was
acquired in 2012, we are also seeing a 
large number of opportunities for further
acquisitions.

06 Alliance Pharma plc | Annual Report 2013

Republic of Ireland

Although competition against 
Nu-Seals has increased ahead of the
anticipated price referencing and generic
substitution changes due in 2014, our
commercial activities have been effective
in maintaining sales at a higher level 
than expected.

The Opus stoma care products acquired 
in 2012 grew strongly at 40%.

China

Alliance is well positioned to benefit from
growth in China’s mother and baby market.
Since 2007, via its joint venture partner, it
has been selling the vitamin / mineral
supplement FushiFu (Forceval) for use in
early pregnancy. 

In 2014 Alliance acquired for £0.5m a 20%
stake in Synthasia, a Shanghai based
company supplying the Chinese market with
Suprememil, its advanced infant milk
formula brand, which it has specially
manufactured for it in Switzerland.
Suprememil has an excellent reputation
amongst the increasing numbers of medium
and high income households. Demand for
high quality baby milk products from abroad
is high within China and the future market
may see further growth following the recent

Business Summary

government announcements relaxing the
one child policy.

Alliance has a shareholder agreement
providing it with joint managerial control
and has options to acquire the remaining
80% stake at pre-agreed performance
multiples over the next 9 years. Synthasia
provides an operating base potentially
enabling Alliance to acquire other products
in the fast-growing China market.

Rest of the World

In June 2013 Alliance acquired the
worldwide rights to Syntometrine. 
Alliance already owned the UK rights to
Syntometrine, an obstetric drug used in
the final stage of labour. This acquisition
added several important new territories
including Australia, South Africa and
Malaysia, thus providing Alliance with new
distributor relationships that may be
valuable in the event of further
acquisitions. 

Far left: Suprememil.
Left: Syntometrine.
Above: FushiFu (Forceval).

Alliance Pharma plc | Annual Report 2013

07

Strategic Report

Alliance returned to double-digit headline profit growth in 2013, with pre-tax profits up by 11% to £12.0m.
This robust performance reflects the resilience of the business and the strength of our increasingly
broad product portfolio. Since 2010 the business has absorbed a reduction in gross margin from
Deltacortril of £11m, a product we acquired in 2006 for less than £1m. Excluding Deltacortril, the
underlying pre-tax profits grew 21% in 2013 and have grown at a compound annual growth rate of 30%
over the past three years, underlining our confidence in our buy and build strategy.

Revenue of the stoma care products, 
which we acquired in October 2012, was
£3.9m, up slightly on the £3.8m pre-
acquisition level. 

Our Gelclair treatment for oral mucositis
accelerated its revenue growth to 16% in
2013 and achieved £1.2m in revenue.

In the first half of 2013 we launched
MolluDab, the first effective treatment for
the highly infectious skin condition
molluscum contagiosum, which was part
of the Beacon Pharmaceuticals acquisition
in 2011. It has been warmly received in
both prescription and over-the-counter
(OTC) markets, with favourable comments
in consumer media such as Mumsnet, and
sales are steadily building.

The planned hand-back of nine products
that we had been distributing for Novartis
has been partly phased through over the
past year and is expected to be completed
soon. These products were generating
some £0.5m of annual gross margin for us,
and we received a termination payment of
about the same amount.

Revenue of our Nu-Seals enteric-coated
low-dose aspirin, sold mainly in the Irish
Republic, has been reducing more slowly
than anticipated since the arrival of
generic competitors during 2012. The
decline of less than £1m to £3.0m
suggests that our strategy of maintaining
relationships with pharmacists through a
contracted sales force is having some
success. The position of Nu-Seals in the
implementation schedule of the long-
anticipated reference pricing and generic
substitution regime means that this may
not impact on prices for some time –
possibly not until late 2014.

In China we had to cut back deliveries 
of Forceval in 2013 as lower than expected
in-market revenue left our distributor
overstocked. The distributor is now re-
stocking and in-market revenue has
recovered somewhat. Elsewhere, there
was an interruption in supply of Forceval
for the UK and other international markets
as a move between contract
manufacturers took longer than expected
and buffer stocks were exhausted before
the new supply commenced.

Financial performance

The gross margin rate in 2013 rose to
60.3% (2012: 55.9%), benefiting from top-
of-cycle revenue of our higher-margin
toxicology product. We expect the
percentage rate to return to closer to 
2012 levels in 2014.

We continue to manage our cost base
carefully. However, in a busy year for new
acquisitions, including a large aborted deal
and the Synthasia International deal
explained below, deal-related costs
totalled £0.9m. Staff costs also increased,
following some recruitment in late 2012 to
support our growing product portfolio and
the build-up of our new Operations team in
2013. As a result, operating costs rose by
£1.4m to £13.7m.

Total marketing investment was broadly
unchanged, with a modest shift from the
dermatology portfolio in favour of the OTC
consumer products where we see scope
for driving more revenue growth. In 2013
these products included MolluDab,
Anbesol for mouth ulcers and teething,
Quinoderm for acne, and Pavacol-D cough
syrup. In 2014 we will also be supporting
Ashton & Parsons Infants’ Powders and
our newly acquired Lypsyl lip care range.

Revenue increased by 1.4% to £45.5m
despite some headwinds, including the
temporary production issues with
ImmuCyst. This augurs well for our
prospects over the next couple of years, 
as we reap the benefits of recent
acquisitions and expect to resume sales 
of ImmuCyst at the end of this year.

With five acquisitions completed in the 
past two years, we have continued to
demonstrate our ability to find and
negotiate attractive deals. Given our strong
funding position and healthy pipeline of
prospective targets, we expect to continue
growth through further acquisitions over
the coming months and years.

ALLIANCE
RETURNED TO
DOUBLE-DIGIT

PROFIT
GROWTH

Trading performance

Our revenue growth in 2013 was
underpinned by the continuing success of
the Hydromol dermatology range. With
revenue up 12% to £5.3m in 2013,
Hydromol is now our largest brand. We are
increasing manufacturing capacity for
Hydromol after demand briefly outstripped
production during the year. 

Our cyclical toxicology product also made 
a significant contribution, particularly in
the first half, as it reached the peak of 
its 30-month sales cycle. However, sales
are now on the cyclical downswing and,
with several competitors entering the
market, we expect future sales to be
markedly lower. 

08 Alliance Pharma plc | Annual Report 2013

 
 
 
 
 
 
 
 
 
 
As a result of the higher revenue and
improved gross margin rate, operating
profit increased 8% to £13.4m (2012:
£12.3m). This represents 29.4% of revenue,
a strong improvement on the 27.4% of
2012. Profit before tax increased 11% to
£12.0m (2012: £10.8m).

Cash generation remained strong, with
free cash flow of £8.4m, albeit this was
lower than the £11.0m of 2012 because of
movements in working capital, particularly
trade and other payables being relatively
high at December 2012 and then relatively
low at December 2013. These movements
are within the normal range of variation
from month to month.

In October 2013 we replaced the bank
facilities, which were due to mature in
2014, with new enlarged facilities that will
be available until June 2018 and are on
improved terms. We now have undrawn
acquisition facilities of over £20m,
positioning us strongly to continue
expanding our product portfolio.

Healthy cash generation enabled us to
finance nearly £10m of acquisitions in 2013
largely from cash flow. Net debt rose by
just £3.2m to £25.0m at the year-end
(2012: £21.8m). The bank debt to EBITDA
ratio remains comfortable at just 1.6 times,
including pre-acquisition EBITDA from the
2013 deals.

Financing

Earnings per share

Holders of our convertible loan stock
continued to convert to equity ahead of 
the maturity date in November 2013, 
and all outstanding stock was converted 
in December. Over recent years 
conversion of loan stock has increased the
number of Alliance shares on the market
by some 16%, with a consequent dilutive
effect on earnings per share. The
completion of conversions brings this
dilution to an end.

Our finance costs reduced again in 2013, 
to £1.4m (2012: £1.5m), benefiting from
conversion of the loan stock. We have
interest rate swaps in place fixing the
LIBOR element of our debt costs at 1.24%
on £20m of our debt until 2018, and so are
well protected against interest rate rises
over the next few years.

Basic EPS improved 6% to 3.82p (2012:
3.61p), while diluted EPS improved 8% to
3.68p (2012: 3.40p). During 2013 the
number of shares in issue increased by
21.0m to 264.1m, 20.0m of which was due
to the loan stock conversions and 1.0m
from exercises of employee share options.

Dividend

We are maintaining our progressive
dividend policy, proposing a final payment
of 0.605 pence per ordinary share to give a
total dividend for the year of 0.908 pence.
This represents an increase of 10% on last
year’s dividend while still maintaining
ample cover of 4.2 times (2012: 4.4 times).
The final dividend will be paid on 10 July
2014 to shareholders on the register on 
13 June 2014.

MAINTAINING
OUR PROGRESSIVE
DIVIDENDP

Y
C
I
L
O

Report of the Directors

FINANCED

NEARLY£10M
OF ACQUISITIONS
IN 2013 LARGELY
FROM CASH FLOW

Strategy

Our long-established business model is
based on acquiring and licensing
established products with stable revenue
in niche areas with limited or no
competition. Most of these require little or
no promotional support. In recent years we
have been broadening the scope of our
portfolio, primarily to include consumer
healthcare products. These typically
require some modest marketing
investment but offer potential for organic
growth; they also help to balance risk
across the portfolio because they are not
exposed to government price control. 

In December 2013 we further expanded
our consumer healthcare portfolio with the
US$3.0m acquisition of the Lypsyl lip care
range. We believe the brand has good
turnaround potential – it was UK market
leader in 2003 but has since suffered from
lack of marketing support. 

Our UK sales force is focused on
dermatology and on specialist hospital
products. As we add further products –
such as MolluDab for the dermatology
team – we will benefit from economies 
of scale. 

We currently generate about a fifth of our
revenue outside the UK. In 2012 we
launched a strategy to increase the flow 
of acquisition opportunities by replicating
our successful UK model in overseas
markets, primarily in Western Europe. In
2012 we appointed Country Managers to
develop product portfolios in France and
Germany. Both operations are now
generating profits: France from the
antimalarial brands acquired in 2012 and
Germany from Irenat, a thyroid product
acquired from Bayer in January 2014. 
With both businesses fully operational 
and profitable we are now well placed to
find and negotiate further acquisitions in
those countries.

Alliance Pharma plc | Annual Report 2013

09

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Strategic Report continued

W ASHTON &
PARSONS
E
INFANTS’
N
POWDERS

N
O
I
T
C
U
D
O
R
P

R
O
F
Y
R
E
N
H
C
A
M

I

We maintain an opportunistic approach to
international products. In June 2013 we
acquired the international rights to the
obstetric drug Syntometrine – a product
we already know well from producing and
marketing it for the UK. International
revenue, which we are managing through
distributors, made a useful contribution to
profits in the second half of the year. 

In January 2014 we supplemented our
existing joint venture in China with a small
investment to take a minority stake in
Synthasia International. We have joint
managerial control and the option to take
full ownership over the next nine years.
Synthasia International, a Shanghai and
Hong Kong based business which markets
Swiss-made infant formula milk in China,
complements the Forceval business as
they are both in the mother and baby
market and sold through largely the same
channels. This gives us an operating base
from which to acquire other products in
the fast-growing Chinese market.

Our project to introduce new production
machinery for Ashton & Parsons Infants’
Powders in partnership with the contract
manufacturer has recently completed. 
We are now ramping-up sales, which 
had been constrained by limited 
production capacity. We have also been
able to increase the product’s consumer
appeal with redesigned packaging in easy-
open sachets.

We look forward to the resumption of
ImmuCyst production at the end of this
year. Sanofi Pasteur has completed
refurbishment of its aseptic manufacturing
plant to address regulatory issues, and the
lengthy process of obtaining approvals is
progressing on schedule. Customers have
switched to using an alternative product,
but there are encouraging indications that
a number intend to return to ImmuCyst. It
is unlikely to regain all of its former 90%
market share, but we expect a steady
build-up of revenue through 2015.

Team

In 2013 we set up a small Operations team
under Stephen Kidner, which is already
making a substantial contribution to
optimising efficiency in the supply chain.

After a decade at the helm, our Chairman,
Michael Gatenby, retires from the
Company at the Annual General Meeting.
He will be succeeded by non-executive
director Andrew Smith, who has been 
with Alliance since 2006. Non-executive
director Paul Ranson, who has also been
with Alliance for 10 years, has also
indicated he intends to retire from the
Board later this year.

Charity

For some years we have been donating
around £20,000 worth of products 
annually to International Health Partners,
a charity that distributes medicines to
doctors in the world’s neediest areas. In
2013 we increased the value of our
contribution to £41,000 including £10,000
cash for the appeal following the
devastation that Typhoon Haiyan caused in
the Philippines.

Outlook

In the UK a new five-year price regulation
regime began at the start of this year,
requiring us to pay a rebate of 3.74% on
sales under the scheme. However, these
now account for less than a third of our
total revenue and the impact on revenue
will be about £0.5m this year.

Our buy and build strategy has been very
effective at producing growth, which at the
headline level has been clouded by
Deltacortril’s decline from its peak of £11m
margin in 2010 to just £0.3m in 2013. At
this level, changes in Deltacortril profits
will no longer mask the benefit of future
acquisitions.

Given the strength of our portfolio, the
acquisitions made in the past couple of
years and the healthy pipeline of
opportunities we are seeing, we are
confident of good revenue and profit
growth over the next few years. We plan to
gain momentum from further acquisitions
during 2014.

Managing capital

Our objective in managing the business’
capital structure is to ensure that Alliance
has the financial capacity, liquidity and
flexibility to support the existing business
and to fund acquisition opportunities as
they arise.

The business is profitable and cash
generative. In line with the bank covenants,
the business is managed to ensure that it
is sufficiently cash generative to meet debt
servicing needs and dividend payments.

10 Alliance Pharma plc | Annual Report 2013

 
 
 
 
 
 
 
 
 
 
F

Report of the Directors

STRONGLY
EXPANDING

POSITIONED TO CONTINUE

Smaller acquisitions are typically financed
purely with bank debt, while larger
acquisitions typically involve a combination
of bank debt and additional equity. The
mixture of debt and equity is varied, taking
into account the desire to maximise the
shareholder returns while keeping gearing 
at comfortable levels.

Risk management

To reduce the risk arising from changes 
in interest rates, the Group uses interest
rate swaps, where appropriate, and the
Convertible Unsecured Loan Stock paid a
fixed coupon. 

The Group’s main transactional currencies
are Sterling and Euros, with the majority of
income and expenditure in Sterling. The
Euro-denominated income matches the
Euro-denominated expenditure quite
closely and so the Group has limited
exposure to exchange rate movements.

Principal risks and
uncertainties

The Group’s principal risks and
uncertainties are outlined below.

Sales volumes being affected by a
change in demand

Changes in demand for pharmaceuticals
products could be caused by a number of
factors, such as changes in the competitive
environment. Key criteria when Alliance
selects products to add to its portfolio are
that the products are in niche areas, with
the majority requiring little or no
promotional support, and that the products
have many years of steady sales history
before acquisition.

Sales volumes being affected by
supply chain constraints

Issues within the supply chain can
interrupt supply leading to insufficient
stock being available to meet demand.
Over the last few years Alliance has taken
a number of measures to strengthen its
supply chain. These include where possible
strengthening the supply chain team within
the business, dual sourcing of some key
products and of some key ingredients,
holding larger buffer stocks of selected
products and improved communication
with suppliers.

Sales pricing being reduced by
regulatory action

Around one third of the Group’s revenues
are from products covered by the
Pharmaceutical Price Regulation Scheme
(PPRS), which is the UK Government’s tool
for controlling pricing for the NHS. Alliance
is a member of the ABPI and other
industry bodies which are consulted by the
Government on changes to PPRS. The
latest scheme commenced in January
2014 and runs for five years. Most of the
other UK revenue is from products that are
medical devices, sold over the counter or
are generic. The regulatory regime for
medical devices allows for inflationary
price increases each year and over the
counter and generic products are freely
priced. In Ireland, a new pricing regime is
being implemented which is likely to
impact Nu-Seals later in 2014.

Cost price inflation affecting 
gross margins

Increases in the cost of goods could erode
gross margins. In a number of cases
Alliance has arrangements with suppliers
which either fix prices or limit price
increases over the next few years. At the
expiry of such arrangements, prices are
tested against prevailing rates in the
market. Alliance also looks for
improvements in production techniques to
reduce the cost of manufacturing.

I

YBROAD
PRODUCT
RANGE

L
G
N
S
A
E
R
C
N

I

Alliance Pharma plc | Annual Report 2013

11

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Board of Directors

Directors who held office at the date of this report are set out below.
All were Directors throughout 2013.

Michael Gatenby – Chairman 136

Michael joined the Board of Alliance as non-executive Chairman in 2004. He had a
successful career in corporate finance for over 25 years, having been a director of Hill
Samuel and Co and vice-chairman of Charterhouse Bank. Michael graduated in Law from
Trinity Hall, Cambridge in 1966 and qualified as a Chartered Accountant in 1969 with Peat,
Marwick, Mitchell (now KPMG LLP).

John Dawson – Chief Executive Officer 4

John founded Alliance in 1996. He gained multi-disciplinary experience in the
pharmaceutical industry over thirty years. John held various senior roles at Sandoz (now
Novartis AG) as director of finance and administration and deputy managing director. John
has a BSc (Pharmacy) and an MSc (Finance) from the London 
Business School.

Richard Wright – Finance Director

Richard joined the Board of Alliance in 2007. He is a Chartered Accountant with over 20
years of experience in financial roles across a variety of sectors. Richard read
Mathematics at Robinson College, Cambridge and qualified as an accountant with Ernst &
Young LLP before joining Somerfield plc. More recently, he held senior finance positions at
FirstGroup plc and Parragon Publishing.

Tony Booley – Executive Director

Tony joined Alliance in 1998. He has had around 30 years experience in the pharmaceutical
and healthcare industries, with positions at Leo Pharma, Glaxo Wellcome (now
GlaxoSmithKline “GSK”) and Getinge Industrier AB. His senior management experience
includes positions in the UK and internationally. Tony graduated in Physiology, has an MBA
from Warwick and is a Chartered Marketer.

12 Alliance Pharma plc | Annual Report 2013

Report of the Directors

Peter Butterfield – Executive Director

Peter joined the board of Alliance in February 2010 following the acquisition of Cambridge
Laboratories, where he spent five years, latterly as UK Commercial Director. He is a Board
Member of the Association of the British Pharmaceutical Industry ("ABPI") and is
chairman of the ABPI Small Companies Forum. Prior to joining Cambridge Laboratories,
Peter spent six years at GlaxoSmithKline. He holds an honours degree in Pharmacology
from the University of Edinburgh.

Thomas Casdagli – Non-Executive Director 4

Thomas joined the board of Alliance as a non-executive director on 3 March 2009. He is a
partner at MVM Life Science Partners LLP, a life science venture capital fund. He has
been an active investor in life sciences since joining MVM in 2002. Before joining MVM,
Thomas worked at PricewaterhouseCoopers LLP where he qualified as a Chartered
Accountant. Thomas graduated in Molecular and Cellular Biochemistry from the
University of Oxford in 1998.

Paul Ranson – Non-Executive Director 245

Paul joined Alliance as a non-executive director in 2003. He has worked in a legal 
capacity in the pharmaceutical sector for over 25 years. He spent the early years of his
career as an in-house lawyer for Smith Kline & French and Merck. Paul specialises
exclusively in the commercial and regulatory aspects of life sciences and he was a partner
in the international law firm Fasken Martineau LLP before his move to Pinsent Masons
LLP in 2013.

Andrew Smith – Non-Executive Director 246

Andrew joined the Board of Alliance in 2006. He has held various senior positions in the
pharmaceutical industry in the UK and USA having been managing director and senior
vice-president of SmithKline Beecham Pharmaceuticals (now GSK), chief executive of
Cerebrus plc until its sale and president international medical marketing services with
Parexel International. Andrew is a founder of Navitas BioPharma Consulting. He
graduated in Natural Sciences from the University of Cambridge.

1 Chairman Audit Committee, 2 Audit Committee member, 3 Chairman Nomination Committee, 
4 Nomination Committee member, 5 Chairman Remuneration Committee, 6 Remuneration Committee member.

Alliance Pharma plc | Annual Report 2013

13

Senior Team Members

Janice Timberlake –
Human Resources Director

Dan Thomas – 
Business Development Director

Dr David Yau – 
Technical & Quality Director RP

Janice joined Alliance in 2011 as HR
Director. She is a Fellow of the Chartered
Institute of Personnel & Development
and has over 20 years of experience in
HR roles across a variety of industry
sectors. Janice’s early career was in the
UK mining industry, followed by Board
roles in the UK division of MyTravel Plc
(formerly Airtours) and latterly the
Natural Environment Research Council.
She is currently a non-executive Director
and Trustee of Plymouth Marine
Laboratory Ltd, and holds a BSc 
honours degree in Geography from 
Hull University.

Since joining Alliance in 2006 Dan has led
Alliance’s M&A and licensing activity,
completing over 14 deals. Dan has
worked in senior management in the
clinical research (CRO) sector, at Chiltern
International and in the biotech research
and diagnostics sector, at R&D Systems
Europe (Techne Corp Inc), responsible for
international regional sales operations.
Dan has worked in Canada, Germany and
France. He holds a first class honours
degree in Applied Biochemistry from
Brunel University. In 2011 Dan won the
PLG/AstraZeneca BD Executive of the
Year award.

David joined Alliance in 2008. He has 
over 25 years of experience in the
pharmaceutical and healthcare 
industries having held positions at 
Reckitt & Colman Pharmaceuticals,
Seven Seas and GlaxoSmithKline. David
graduated with a PhD and an MBA from
the University of Bradford.

Margaret Boulton – 
Medical & Regulatory Affairs Director

Stephen Kidner – 
Operations Director 

Sarah Robinson – 
Company Secretary

Margaret joined Alliance in 2009. She has
around twenty years of experience in the
pharmaceutical and healthcare
industries, with Regulatory/Scientific
Affairs positions at Abbott, Baxter and
Élan. Margaret graduated in Animal
Science at Nottingham, has a PhD from
Edinburgh and an MBA from Bath.

Stephen joined Alliance in August 2013
bringing a background in development,
manufacturing and supply chain
management gained in the
pharmaceutical industry over a 23 year
career with Wyeth and Mundipharma
International. 

A science graduate, Stephen holds a MSc
in Pharmaceuticals and an MBA.

Sarah joined Alliance in 2010 as the
Company Secretary. She has worked in
Asia, the UK and the USA, was Company
Secretary for the Financial Times and has
further experience in the financial
services and health sector. A Chartered
Secretary, Sarah gained her MBA from
Southampton University.

14 Alliance Pharma plc | Annual Report 2013

Corporate Governance

Report of the Directors

Introduction
Alliance Pharma plc is an AIM listed company and the Board is committed to achieving good standards
of corporate governance, integrity and business ethics.

Responsibilities of the Board

Management Teams

The Board is responsible to the
shareholders for:

l Setting the Group’s strategy
l Maintaining the policy and decision-
making process around which the
strategy is implemented

l Ensuring that necessary financial and
human resources are in place to meet
strategic aims

l Monitoring performance against key
financial and non-financial indicators

l Providing leadership whilst maintaining

the controls for managing risk

l Overseeing the system of risk

management

l Setting values and standards in
corporate governance matters.

There is a list of matters reserved for the
Board which may be updated by the Board
and approved by the Board only. 

The Chairman is responsible for leading
the Board, facilitating the effective
contribution of all members and ensuring
that it operates effectively in the interests
of the shareholders. The Chief Executive
Officer is responsible for the leadership of
the business and implementation of the
strategy. The Company Secretary is
responsible, on behalf of the Chairman, for
ensuring that all Board and Committee
meetings are conducted properly, that the
Directors receive the appropriate
information prior to the meeting, for
ensuring that governance requirements
are considered and implemented and for
accurately recording each meeting. The
Directors may have access to independent
professional advice, where needed, at the
Group’s expense.

During 2013 the Board delegated
management of the business to the
Corporate Organisation Team and the UK
and International Review and Planning
Teams. The Executive Team, which
comprises the Executive Directors, is the
chief operating decision maker and
attended the Corporate Organisation Team
and Review and Planning team meetings.

Reporting Structure

Committees

The Board has an Audit Committee, a
Nominations Committee and a
Remuneration Committee, each with
written terms of reference. The terms of
reference are available on the Group
website. The Report of the Remuneration
Committee and Report of the Nominations
Committee form part of this governance
section. Each Committee reports to the
Board on its activities.

Meetings

The Board meets regularly on pre-
determined dates and has a strategy
meeting each year consisting of the Board
and other Senior Managers, the purpose of
which is to discuss progress on the
strategy, to review the long term strategy
and develop the strategic framework for
the achievement of the Group’s targets.
During 2013 the Board held ten scheduled
meetings and all members of the Board
attended all of those meetings. In addition
there were a number of ad-hoc meetings.

Non-Executive Directors

The role of the non-executive directors 
is to:

l Challenge constructively and help
develop proposals on strategy

l Satisfy themselves as to the financial
integrity of the financial information

l Satisfy themselves as to the robustness

of the controls

l Ensure that the systems of risk

management are robust and defensible

l Review management performance and
the monitoring and reporting of such
performance.

They have a role in determining the pay
and benefits of the Executive Directors, to
play a key role in the appointment and, if
necessary, removal of Executive Directors
and Board succession.

Relations with Shareholders

At each meeting, the Board is updated on
the meetings and communications with the
shareholders and an analysis of the
shareholder base is presented. Research
notes by brokers are circulated to all Board
members. Throughout the year the Chief
Executive Officer and Finance Director
meet with the large, institutional
shareholders who hold the majority of the
shares. Regular feedback is given to the
Board following meetings with the
shareholders from the financial PR
advisors, and from the shareholders via
the brokers.

The Group recognises that whilst the
majority of the shares are held by large
institutions, attention should be paid to the
private shareholders and the Investor
Relations section of the Group’s website is
regularly updated and amended with the
aim being to provide good information to
all shareholders, particularly private
investors. The website provides a facility to
receive email alert notifications of Group
news and stock exchange announcements.
In addition the Chief Executive Officer and
Finance Director regularly present at
conferences attended by many potential
and current private shareholders and meet
with Private Client Fund Managers
representing the interests of private
investors following which feedback is 
given to the Group. 

At the Annual General Meeting the
Chairman issues a statement on current
trading. Directors are available following
the meeting to answer questions and for
informal discussions. The results of the
proxy votes are announced at the meeting,
including the abstentions, and these are
published on the website following the
meeting.

Alliance Pharma plc | Annual Report 2013

15

Directors’ Remuneration

Remuneration Committee

The members of the Remuneration Committee are:

Paul Ranson (Chairman of the Remuneration Committee)

Thomas Casdagli (appointed 9 September 2013)

Michael Gatenby

Andrew Smith

The Company Secretary attends the meetings of the Remuneration Committee as secretary to the Remuneration Committee. The Chief
Executive Officer and the Human Resources Director are also invited to attend certain meetings of the Remuneration Committee.

There were 6 Remuneration Committee meetings held during the year.

The Large and Medium-sized Companies and Groups (Accounts and Reports) (Amendment) Regulations 2013 do not apply to companies
quoted on AIM; the Remuneration Committee is committed to use the Regulations to influence the Report and follow best practice where
appropriate.

The terms of reference of the Remuneration Committee are available on www.alliancepharma.co.uk

Role of the Remuneration Committee

The Remuneration Committee reviews and determines on behalf of the Board and shareholders of the Company the pay, benefits and
other terms of service of the Executive Directors of the Company and the broad pay strategy with respect to senior Company employees.

Remuneration Policy

The objective of the Company’s remuneration policy is to attract and retain the directors and senior executives needed to run the
Company in a cost-effective manner.

The remuneration policy of the Company has four principal components:

1. Basic Salaries and Benefits in Kind – Basic salaries are determined by the Remuneration Committee bearing in mind the salaries

paid in AIM-listed and other small market capitalisation healthcare companies. Within that frame of reference, it is intended that pay
should be at or near the median level. Benefits in kind include the provision of company cars (or a salary alternative).

2. Bonuses – Bonuses are payable to staff according to the achievement by the Group of certain pre-determined earnings targets. The

level of bonuses payable on achievement of the targets is set at the level perceived appropriate to provide the necessary incentives for
Executive Directors and Senior Managers. There are appropriate adjustments to the bonus payable in the event of over- or under-
achievement of the Group against those targets. In addition, bonuses are adjusted for personal performance and the amount of bonus
paid will reflect any substantial periods of absence or unavailability of the employee.

3. Share Options Scheme – The Company has in place a share option scheme covering all employees, under which share options are
normally granted once a year. The exercise price of the options granted under the scheme is set equal to the market value of the
company's shares at the time of grant. The share option scheme is overseen by the Remuneration Committee which shall determine
the terms under which eligible individuals may be invited to participate. The scheme is normally an HMRC approved scheme but may
be unapproved in relation to certain individuals.

4. Pensions –There is a defined contribution scheme for all Executive Directors and employees. Only basic salaries are pensionable,

except in the case of Tony Booley, whose bonus is also pensionable. 

Directors’ Remuneration

The aggregate remuneration payable to the directors during the period was as follows:

                                                         Salary                                 Bonus                                 Other                              Pension               Total Remuneration
                                                2013             2012             2013             2012             2013             2012             2013             2012             2013             2012

A R Booley                    153,001       149,074         35,908         35,117           2,114           1,932         17,792         17,544      208,815       203,667
P J Butterfield              153,001       148,536         45,063         43,896              473           2,373         14,280         13,834      212,817       208,639
T T Casdagli                              -                   -                   -                   -                   -                   -                   -                   -                   -                   -
J Dawson                      209,076       202,900         49,904         48,612           6,086           4,503         10,000         10,000      275,066       266,015
M R B Gatenby                74,246         71,925                   -                   -              770              648                   -                   -         75,016         72,573
P M Ranson                    33,791         32,736                   -                   -                   -                   -                   -                   -         33,791         32,736
A L Smith                        33,791         32,736                   -                   -              499              940                   -                   -         34,290         33,676
R D Wright                    153,001       148,536         36,050         34,838           1,610           1,732         14,280         13,834      204,941       198,940

                                      809,907       786,443      166,925       162,463         11,552         12,128         56,352         55,212   1,044,736    1,016,246

16 Alliance Pharma plc | Annual Report 2013

Report of the Directors

Directors’ Remuneration continued

                                                                                                                                    Total Remuneration    Share based payments                   Total          
                                                                                                                                         2013             2012             2013             2012             2013             2012

A R Booley                                                                                                     208,815       203,667         20,227          13,014       229,042        216,681
P J Butterfield                                                                                               212,817       208,639         80,077        104,780       292,894        313,419
T T Casdagli                                                                                                               -                   -                   -                     -                     -                     -
J Dawson                                                                                                       275,066       266,015                   -                     -       275,066        266,015
M R B Gatenby                                                                                                75,016         72,573                   -                     -         75,016          72,573
P M Ranson                                                                                                     33,791         32,736                   -                     -         33,791          32,736
A L Smith                                                                                                         34,290         33,676                   -                     -         34,290          33,676
R D Wright                                                                                                     204,941       198,940         20,258          13,115       225,199        212,055

                                                                                                                                1,044,736     1,016,246       120,562        130,909    1,165,298     1,147,155

Directors’ Service Contracts

All Executive Directors are employed under service contracts. The services of all Executive Directors may be terminated by the provision
of a maximum of 12 months’ notice by the Company.

Directors’ Share Options

Details of options for the directors who served during the year are as follows:

                                      Number 2012                    Granted                         Exercised                 Number 2013
                                             Not subject to           Subject to   Not subject to           Subject to   Not subject to          Subject to   Not subject to           Subject to              Exercise           Date from
                                               performance     performance     performance     performance     performance    performance     performance     performance                    price                  which                  Expiry
                                                    conditions          conditions          conditions          conditions          conditions          conditions          conditions          conditions                (pence)        exercisable                     date

A R Booley              110,000                 -                 -                 -                 -                 -     110,000                 -            7.75    13/04/12    12/04/19
                                116,500                 -                 -                 -                 -                 -     116,500                 -          34.25    29/04/13    28/04/20
                                130,000                 -                 -                 -                 -                 -     130,000                 -          34.12    28/04/14    27/04/21
                                140,000                 -                 -                 -                 -                 -     140,000                 -          29.25    19/10/15    18/10/22
                                            -                 -      144,200                 -                 -                 -     144,200                 -          37.25    06/06/16    05/06/23
                                            -                 -                 -      400,000                 -                 -                 -     400,000          35.75    23/10/18    22/10/23

P J Butterfield     1,000,000                 -                 -                 -                 -                 -  1,000,000                 -          33.25    26/03/13    25/03/20
                                115,000                 -                 -                 -                 -                 -     115,000                 -          34.25    29/04/13    28/04/20
                             1,130,000                 -                 -                 -                 -                 -  1,130,000                 -          34.12    28/04/14    27/04/21
                                140,000                 -                 -                 -                 -                 -     140,000                 -          29.25    19/10/15    18/10/22
                                            -                 -      144,200                 -                 -                 -     144,200                 -          37.25    06/06/16    05/06/23
                                            -                 -                 -      400,000                 -                 -                 -     400,000          35.75    23/10/18    22/10/23

R D Wright              649,376                 -                 -                 -      649,376                 -                 -                 -            8.50    23/04/11    22/04/18
                                113,000                 -                 -                 -      113,000                 -                 -                 -            7.75    13/04/12    12/04/19
                                118,650                 -                 -                 -                 -                 -     118,650                 -          34.25    29/04/13    28/04/20
                                130,000                 -                 -                 -                 -                 -     130,000                 -          34.12    28/04/14    27/04/21
                                140,000                 -                 -                 -                 -                 -     140,000                 -          29.25    19/10/15    18/10/22
                                            -                 -      144,200                                    -                 -     144,200                 -          37.25    06/06/16    05/06/23
                                            -                 -                 -      400,000                 -                 -                 -     400,000          35.75    23/10/18    22/10/23

The market price of ordinary shares at 31 December 2013 was 41.00 pence and the range during the period was from 31.85 pence to
41.00 pence.

Alliance Pharma plc | Annual Report 2013

17

Other Matters

Principal activities

The principal activity of the Group is the acquisition, marketing and distribution of pharmaceutical products. The principal activity of the
Company is to act as a holding company.

Directors

The following table shows the beneficial interests of the Directors (and their spouses and minor children) in the shares of the Company.

                                                                                                                                                                  Ordinary shares
                                                                                                                                                                                                                 At start of year 
                                                                                                                        Beneficial       Non-beneficial                                        or subsequent
                                                                                                                            interest                   interest        At end of year           appointment
                                                                                                                           Number                  Number                  Number                  Number

Anthony Booley                                                                                               4,610,723                               -               4,610,723                4,610,723
Peter Butterfield                                                                                                           -                               -                               -                               -
Thomas Casdagli                                                                                                 26,101              24,035,799             24,061,900              19,302,144
John Dawson                                                                                                39,576,402              20,000,000             59,576,402              60,036,402
Michael Gatenby                                                                                                350,000                               -                   350,000                   350,000
Paul Ranson                                                                                                         48,000                               -                     48,000                     48,000
Andrew Smith                                                                                                    200,000                               -                   200,000                   200,000
Richard Wright                                                                                                   190,768                               -                   190,768                   190,768

On 17 January 2014, Mrs Lynette Booley, wife of Mr Anthony Booley, sold 300,000 Shares at 33.5p.

Directors’ Responsibilities Statement

The directors are responsible for preparing the Strategic Report and the Directors’ Report and the financial statements in accordance
with applicable law and regulations.

Company law requires the directors to prepare financial statements for each financial year. Under that law the directors have elected to
prepare the Group financial statements and the Company financial statements in accordance with International Financial Reporting
Standards as adopted by the European Union (IFRSs). Under company law the directors must not approve the financial statements unless
they are satisfied that they give a true and fair view of the state of affairs and profit or loss of the company and group for that period. In
preparing these financial statements, the directors are required to:

l select suitable accounting policies and then apply them consistently;
l make judgments and accounting estimates that are reasonable and prudent;
l state whether applicable IFRSs have been followed, subject to any material departures disclosed and explained in the financial

statements;

l prepare the financial statements on the going concern basis unless it is inappropriate to presume that the company will continue in

business.

The directors are responsible for keeping adequate accounting records that are sufficient to show and explain the company’s transactions
and disclose with reasonable accuracy at any time the financial position of the company and enable them to ensure that the financial
statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the company and hence for
taking reasonable steps for the prevention and detection of fraud and other irregularities.

The Directors confirm that:

l so far as each of the directors is aware there is no relevant audit information of which the company’s auditor is unaware; and
l the directors have taken all steps that they ought to have taken to make themselves aware of any relevant audit information and to

establish that the auditors are aware of that information.

The directors are responsible for the maintenance and integrity of the corporate and financial information included on the company’s
website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements may differ from
legislation in other jurisdictions. 

Financial risk management objectives and policies

The Group monitors credit risk closely and considers that its current policies of credit checks meets its objectives of managing exposure
to credit risk. The Group’s other financial risk management policies and objectives are detailed in note 21 of the financial statements.

18 Alliance Pharma plc | Annual Report 2013

Report of the Directors

Disabled employees

Applications for employment by disabled persons are fully considered, bearing in mind the aptitudes of the applicant concerned. In the
event of members of staff becoming disabled, every effort is made to ensure that their employment with the Group continues and that
appropriate training is arranged. It is the policy of the Group that the training, career development and promotion of disabled persons
should, as far as possible, be identical to that of other employees.

Employee information and consultation

The Group continues to involve its staff in the future development of the business. Information is provided to employees through the Group
website, intranet site and by regular briefing meetings.

The Group operates a Group Personal Pension Plan and a Stakeholder Pension Plan which is available to all employees.

Going concern

As explained in the Strategic Report, the current rate of cash generation by the Group comfortably exceeds the capital and debt 
servicing needs of the business (though there cannot, of course, be absolute certainty that the rate of cash generation will be
maintained). The Board remains confident that all the bank covenants will continue to be met. The Group has a £5m Working Capital
Facility which is largely undrawn and which the Board believes should comfortably satisfy the Group’s working capital needs for at least
the next 12 months.

After making enquiries, the Directors have formed a judgement that there is reasonable expectation that the Group has adequate
resources to continue in operational existence for the foreseeable future. For this reason, the Directors continue to adopt the going
concern basis in preparing the financial statements.

Political and charitable donations

Charitable donations totalling £42,792 (2012: £19,151) were made during the year. There were no political donations made during the
period.

Auditor

A resolution to re-appoint Grant Thornton UK LLP as auditor for the next year will be proposed at the annual general meeting in
accordance with section 489 of the Companies Act 2006.

Annual General Meeting

The 2014 Annual General Meeting of the Company will be held on 21 May 2014, the business of which is set out in the Notice of Meeting.

On behalf of the Board

Sarah Robinson
Company Secretary
25 March 2014 

Alliance Pharma plc | Annual Report 2013

19

Independent Auditor’s Report 
to the members of Alliance Pharma plc

We have audited the financial statements of Alliance Pharma plc for the year ended 31 December 2013 which comprise the consolidated
income statement, the consolidated statement of comprehensive income, the consolidated balance sheet, the company balance sheet,
the consolidated statement of changes in equity, company statement of changes in equity, and the consolidated and company cash flow
statements and the related notes. The financial reporting framework that has been applied in their preparation is applicable law and
International Financial Reporting Standards (IFRSs) as adopted by the European Union and, as regards the parent company financial
statements, as applied in accordance with the provisions of the Companies Act 2006.

This report is made solely to the company’s members, as a body, in accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our
audit work has been undertaken so that we might state to the company’s members those matters we are required to state to them in an
auditor’s report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone
other than the company and the company’s members as a body, for our audit work, for this report, or for the opinions we have formed.

Respective responsibilities of directors and auditor

As explained more fully in the Directors’ Responsibilities Statement, the directors are responsible for the preparation of the financial
statements and for being satisfied that they give a true and fair view. Our responsibility is to audit and express an opinion on the financial
statements in accordance with applicable law and International Standards on Auditing (UK and Ireland). Those standards require us to
comply with the Auditing Practices Board’s (APB’s) Ethical Standards for Auditors.

Scope of the audit of the financial statements

A description of the scope of an audit of financial statements is provided on the Financial Reporting Council's website at
www.frc.org.uk/apb/scope/private.cfm.

Opinion on financial statements

In our opinion:

l the financial statements give a true and fair view of the state of the group's and of the parent company's affairs as at 31 December

2013 and of the group's profit for the year then ended; 

l the group financial statements have been properly prepared in accordance with IFRSs as adopted by the European Union; and
l the parent company financial statements have been properly prepared in accordance with IFRSs as adopted by the European Union

and as applied in accordance with the provisions of the Companies Act 2006; and

l the financial statements have been prepared in accordance with the requirements of the Companies Act 2006.

Opinion on other matter prescribed by the Companies Act 2006

In our opinion the information given in the Strategic Report and Directors' Report for the financial year for which the financial statements
are prepared is consistent with the financial statements.

Matters on which we are required to report by exception

We have nothing to report in respect of the following matters where the Companies Act 2006 requires us to report to you if, in our opinion:

l adequate accounting records have not been kept by the parent company, or returns adequate for our audit have not been received from

branches not visited by us; or

l the parent company financial statements are not in agreement with the accounting records and returns; or
l certain disclosures of directors’ remuneration specified by law are not made; or
l we have not received all the information and explanations we require for our audit.

Norman Armstrong
Senior Statutory Auditor
for and on behalf of Grant Thornton UK LLP
Statutory Auditor, Chartered Accountants
Bristol
25 March 2014

20 Alliance Pharma plc | Annual Report 2013

Consolidated Income Statement

Financial Statements

                                                                                                                                                                                     Year ending             Year ending 
                                                                                                                                                                                  31 December          31 December
                                                                                                                                                                                                 2013                        2012
                                                                                                                                                               Notes                      £000s                      £000s

Revenue                                                                                                                                                         3                     45,513                     44,897
Cost of sales                                                                                                                                                                      (18,072)                   (19,779)

Gross profit                                                                                                                                                                          27,441                     25,118

Operating expenses                                                                                                                                                                                                         
Administration and marketing expense                                                                                                                         (13,027)                   (11,856)
Amortisation of intangible assets                                                                                                                                         (422)                        (573)
Share-based employee remuneration                                                                                                        6                       (632)                        (369)

                                                                                                                                                                                           (14,081)                   (12,798)

Operating profit                                                                                                                                                                  13,360                     12,320

Finance costs                                                                                                                                                                                                                    
Interest payable and similar charges                                                                                                         5                    (1,281)                     (1,541)
Interest income                                                                                                                                             5                              2                               -
Other finance (charges)/income                                                                                                                  5                          (72)                            30

                                                                                                                                                                                             (1,351)                     (1,511)

Profit on ordinary activities before taxation                                                                                             4                     12,009                     10,809
Taxation                                                                                                                                                          7                    (2,425)                     (2,119)

Profit for the year attributable to equity shareholders                                                                                                    9,584                       8,690

Earnings per share                                                                                                                                                                                                          
Basic (pence)                                                                                                                                                 9                         3.82                         3.61
Diluted (pence)                                                                                                                                              9                         3.68                         3.40

All of the activities of the Group are classed as continuing.

The accompanying accounting policies and notes form an integral part of these financial statements.

Alliance Pharma plc | Annual Report 2013

21

Consolidated Statement of
Comprehensive Income

                                                                                                                                                                                     Year ending             Year ending 
                                                                                                                                                                                  31 December          31 December
                                                                                                                                                                                                 2013                        2012
                                                                                                                                                                                               £000s                      £000s

Profit for the period                                                                                                                                                              9,584                       8,690

Other comprehensive income

Other items recognised directly in equity
Items that may be reclassified to profit or loss                                                                                                                                                            
Interest rate swaps – cash flow hedge                                                                                                                                   443                              6
Deferred tax on interest rate swaps                                                                                                                                       (93)                            (2)

Total comprehensive income for the period                                                                                                                      9,934                       8,694

22 Alliance Pharma plc | Annual Report 2013

Consolidated Balance Sheet

Financial Statements

                                                                            31 December    31 December    31 December    31 December          1 January          1 January
                                                                                           2013                   2013                   2012                   2012                   2012                   2012 
                                                                Note                £000s                £000s                 £000s                 £000s                 £000s                 £000s

Assets                                                                                                                                                                                                                               
Non-current assets                                                                                                                                                                                                        
Intangible assets                                        10               89,061                                              79,890                                           66,130                           
Property, plant and equipment                 11                     592                                                   564                                                765                           
Derivative financial instruments              22                     443                                                       -                                                    -                           

                                                                                                                    90,096                                           80,454                                           66,895

Current assets                                                                                                                                                                                                                 
Inventories                                                  13                 5,468                                                5,393                                             5,652                           
Trade and other receivables                     14               10,539                                              10,145                                             8,660                           
Cash and cash equivalents                       15                     888                                                4,634                                             1,079                           

                                                                                                                    16,895                                           20,172                                           15,391

Total assets                                                                                              106,991                                         100,626                                           82,286

Equity                                                                                                                                                                                                                                
Ordinary share capital                               25                 2,641                                                2,430                                             2,401                           
Share premium account                                               29,380                                              25,297                                           24,866                           
Share option reserve                                                       1,424                                                   792                                                423                           
Reverse takeover reserve                                                (329)                                                 (329)                                              (329)                           
Other reserve                                                                      350                                                       -                                                  (4)                           
Retained earnings                                                         31,202                                              23,658                                           16,771                           

Total equity                                                                                                 64,668                                           51,848                                           44,128

Liabilities                                                                                                                                                                                                                         
Non-current liabilities                                                                                                                                                                                                   
Long term financial liabilities                   18               20,881                                              20,225                                           15,225                           
Convertible debt                                    18,19                         -                                                       -                                             4,460                           
Other liabilities                                           20                         -                                                     20                                                  40                           
Deferred tax liability                                  23                 6,294                                                6,124                                             4,064                           
Provisions for other liabilities                   24                     199                                                   364                                                510                           

                                                                                                                    27,374                                           26,733                                           24,299

Current liabilities                                                                                                                                                                                                            
Cash and cash equivalents                       15                 2,125                                                       1                                                    1                           
Financial liabilities                                     18                 2,895                                                6,250                                             4,250                           
Convertible debt                                    18,19                         -                                                4,189                                                    -                           
Corporation tax                                                                1,154                                                1,322                                             1,046                           
Trade and other payables                          17                 8,585                                              10,086                                             8,367                           
Derivative financial instruments              22                         -                                                       -                                                    6                           
Provisions for other liabilities                   24                     190                                                   197                                                189                           

                                                                                                                    14,949                                           22,045                                           13,859

Total liabilities                                                                                           42,323                                           48,778                                           38,158

Total equity and liabilities                                                                      106,991                                         100,626                                           82,286

The financial statements were approved by the Board of Directors on 25 March 2014.

John Dawson                                     Richard Wright
Director                                               Director

The accompanying accounting policies and notes form an integral part of these financial statements. Company number 04241478

Alliance Pharma plc | Annual Report 2013

23

Company Balance Sheet

                                                                            31 December    31 December    31 December    31 December          1 January          1 January
                                                                                           2013                   2013                   2012                   2012                   2012                   2012 
                                                                Note                £000s                £000s                 £000s                 £000s                 £000s                 £000s

Assets                                                                                                                                                                                                                               
Non-current assets                                                                                                                                                                             
Investment in subsidiaries                        12               47,119                                              37,618                                           36,402                           

                                                                                                                  47,119                                           37,618                                           36,402
Current assets                                                                                                                                                                                                                 
Trade and other receivables                     14                       50                                           10,021                                             2,020                           
Cash and cash equivalents                       15                       12                                                182                                                  77                           

                                                                                                                          62                                           10,203                                             2,097

Total assets                                                                                              47,181                                           47,821                                           38,499

Equity                                                                                                                                                                                                                                
Ordinary share capital                               25                 2,641                                                2,430                                             2,401                           
Share premium account                                               29,380                                              25,297                                           24,866                           
Share option reserve                                                       1,424                                                   792                                                423                           
Retained earnings                                                         13,527                                              14,719                                             6,028                           

Total equity                                                                                               46,972                                           43,238                                           33,718
Liabilities                                                                                                                                                                                                                         
Non-current liabilities                                                                                                                                                                                                   
Convertible debt                                    18,19                         -                                                       -                                             4,460                           

                                                                                                                               -                                                    -                                             4,460
Current liabilities                                                                                                                                                                                                            
Convertible debt                                    18,19                         -                                                4,189                                                    -                           
Corporation tax                                                                        -                                                       4                                                    -                           
Trade and other payables                          17                     209                                                   390                                                321                           

                                                                                                                          209                                             4,583                                                321

Total liabilities                                                                                                 209                                             4,583                                             4,781

Total equity and liabilities                                                                        47,181                                           47,821                                           38,499

The financial statements were approved by the Board of Directors on 25 March 2014.

John Dawson                                     Richard Wright
Director                                               Director

The accompanying accounting policies and notes form an integral part of these financial statements. Company number 04241478

24 Alliance Pharma plc | Annual Report 2013

Consolidated Statement of 
Changes in Equity

Financial Statements

                                                             Ordinary                  Share                  Share              Reverse
                                                                  share            premium                 option            takeover                  Other            Retained                    Total
                                                                capital              account              reserve              reserve              reserve            earnings                 equity
                                                                  £000s                  £000s                  £000s                  £000s                  £000s                  £000s                  £000s

Balance 1 January 2012                       2,401                24,866                     423                   (329)                       (4)                16,771                44,128

Issue of shares                                           29                     431                         -                         -                         -                         -                     460
Dividend paid                                                -                         -                         -                         -                         -                (1,803)                (1,803)
Share options charge                                   -                         -                     369                         -                         -                         -                     369

Transactions with owners                         29                     431                     369                         -                         -                (1,803)                   (974)

Profit for the period                                      -                         -                         -                         -                         -                  8,690                  8,690
Other comprehensive income                                                                                                                                                                                       
Interest rate swaps – 
cash flow hedge                                            -                         -                         -                         -                         6                         -                         6
Deferred tax on interest rate swap             -                         -                         -                         -                       (2)                         -                       (2)

Total comprehensive income 
for the period                                               -                         -                         -                         -                         4                  8,690                  8,694

Balance 31 December 2012                 2,430                25,297                     792                   (329)                         -                23,658                51,848

Balance 1 January 2013                       2,430                25,297                     792                   (329)                         -                23,658                51,848

Issue of shares                                         211                  4,083                         -                         -                         -                         -                  4,294
Dividend paid                                                -                         -                         -                         -                         -                (2,040)                (2,040)
Share options charge                                   -                         -                     632                         -                         -                         -                     632

Transactions with owners                       211                  4,083                     632                         -                         -                (2,040)                  2,886

Profit for the period                                      -                         -                         -                         -                         -                  9,584                  9,584
Other comprehensive income                                                                                                                                                                                       
Interest rate swaps – 
cash flow hedge                                            -                         -                         -                         -                     443                         -                     443
Deferred tax on interest rate swap             -                         -                         -                         -                     (93)                         -                     (93)

Total comprehensive income 
for the period                                               -                         -                         -                         -                     350                  9,584                  9,934

Balance 31 December 2013                2,641                 29,380                   1,424                    (329)                       350                 31,202                 64,668

The balance on the share premium account may not be legally distributed under section 831 of the Companies Act 2006.

Alliance Pharma plc | Annual Report 2013

25

Company Statement of 
Changes in Equity 

                                                                                                                      Ordinary                  Share                  Share
                                                                                                                            share            premium                 option            Retained                    Total
                                                                                                                          capital              account              reserve            earnings                 equity
                                                                                                                           £000s                  £000s                  £000s                  £000s                  £000s

Balance 1 January 2012                                                                             2,401                24,866                     423                  6,028                33,718

Issue of shares                                                                                                 29                     431                         -                         -                     460
Dividend paid                                                                                                      -                         -                         -                (1,803)                (1,803)
Share options charge                                                                                         -                         -                     369                         -                     369

Transactions with owners                                                                               29                     431                     369                (1,803)                   (974)

Profit for the period                                                                                            -                         -                         -                10,494                10,494

Balance 31 December 2012                                                                       2,430                25,297                     792                14,719                43,238

Balance 1 January 2013                                                                             2,430                25,297                     792                14,719                43,238

Issue of shares                                                                                               211                  4,083                         -                         -                  4,294
Dividend paid                                                                                                      -                         -                         -                (2,040)                (2,040)
Share options charge                                                                                         -                         -                     632                         -                     632

Transactions with owners                                                                             211                  4,083                     632                (2,040)                  2,886

Profit for the period                                                                                            -                         -                         -                     848                     848

Balance 31 December 2013                                                                      2,641                 29,380                   1,424                 13,527                 46,972

The balance on the share premium account may not be legally distributed under section 831 of the Companies Act 2006.
The profit for the year dealt with in the financial statements of the parent company was £848,000 (2012: Profit £10,494,000).
As permitted by section 408 of the Companies Act 2006, no separate income statement is presented in respect of the parent company.

26 Alliance Pharma plc | Annual Report 2013

                                                                                                                                                                                                                                          
Consolidated and Company 
Cash Flow Statements

Financial Statements

                                                                                                                                                                       Group                                           Company
                                                                                                                                     Year ended        Year ended       Year ended        Year ended
                                                                                                                                  31 December    31 December    31 December    31 December
                                                                                                                                                 2013                   2012                   2013                   2012
                                                                                                                      Note                £000s                 £000s                £000s                 £000s

Cash flows from operating activities                                                                                                                                                 
Cash generated from operations                                                                   27               12,546                14,417                    (23)                       (2)
Tax paid                                                                                                                                (2,516)                (1,982)                      (4)                         4

Cash flows from operating activities                                                                                 10,030                12,435                    (27)                         2

Investing activities                                                                                                                                                                               
Interest received                                                                                                                           2                         -                 1,464                  1,310
Dividend received                                                                                                                          -                         -               10,000                  2,000
Investment in subsidiary                                                                                                              -                         -               (9,501)                (1,435)
Payment of deferred consideration                                                                                        (20)                     (20)                         -                         -
Development costs capitalised                                                                       10                    (63)                   (107)                         -                         -
Net assets acquired in Opus, net of cash                                                                                   -                   (422)                         -                         -
Purchase of property, plant and equipment                                                 11                  (298)                     (73)                         -                         -
Purchase of other intangible assets                                                              10               (9,534)              (12,377)                         -                         -

Net cash (used in) / received from investing activities                                                    (9,913)              (12,999)                 1,963                  1,875

Financing activities                                                                                                                                                                              
Interest paid and similar charges                                                                                     (1,232)                (1,198)                  (148)                   (352)
Loan issue costs                                                                                                                    (500)                   (100)                         -                         -
Proceeds from exercise of share options                                                                                 82                     190                       82                     164
Dividend paid                                                                                                                       (2,040)                (1,803)               (2,040)                (1,803)
Transfer from subsidiary undertakings                                                                                      -                         -                         -                     219
Receipt from borrowings                                                                                                    28,500                10,000                         -                         -
Repayment of borrowings                                                                                                 (30,725)                (3,000)                         -                         -

Net cash (used in) / received from financing activities                                                   (5,915)                  4,089               (2,106)                (1,772)

Net movement in cash and cash equivalents                                                                 (5,798)                  3,525                  (170)                     105

Cash and cash equivalents at the beginning of the period                                              4,633                  1,078                     182                       77
Exchange (losses) / gains on cash and cash equivalents                                                    (72)                       30                         -                         -

Cash and cash equivalents at the end of the period                                  15               (1,237)                  4,633                       12                     182

The accompanying accounting policies and notes form an integral part of these financial statements. 

Alliance Pharma plc | Annual Report 2013

27

Notes to the Financial 
Statements
for year ended 31 December 2013

1. General information

Alliance Pharma plc (‘the Company’) and its subsidiaries (together ‘the Group’) acquire, market and distribute pharmaceutical and other
medical products. The Company is a public limited company incorporated and domiciled in England. The address of its registered office is
Avonbridge House, Bath Road, Chippenham, Wiltshire, SN15 2BB. 

The Company is listed on the AIM stock exchange.

These consolidated financial statements have been approved for issue by the Board of Directors on 25 March 2014.

2. Summary of significant accounting policies

The principal accounting policies applied in the preparation of these consolidated financial statements are set out below. IFRS 13 has
been applied for the first time in these financial statements. These policies have been consistently applied to all the periods presented,
unless otherwise stated.

2.1 Basis of preparation

These financial statements have been prepared in accordance with International Financial Reporting Standards as adopted by the EU and
with those parts of the Companies Act 2006 applicable to companies reporting under IFRS. The financial statements have been prepared
under the historical cost convention, with the exception of derivatives which are included at fair value. A summary of the more important
Group and Company accounting policies are set out below. The preparation of financial statements in conformity with generally accepted
accounting principles requires the use of estimates and assumptions in these statements, particularly in relation to determining the
useful economic life of assets, that affect the reported amounts of assets and liabilities at the date of the financial statements and the
reported amounts of revenues and expenses during the reporting period. Although these estimates are based on management’s best
knowledge of the amount, event or actions, actual results ultimately may differ from those estimates.

2.2 Consolidation

The consolidated balance sheet includes the assets and liabilities of the company and its subsidiaries which are made up to 31 December
2013. Entities over which the Group has the ability to exercise control are accounted for as subsidiaries. Interests acquired in entities are
consolidated from the effective date of acquisition and interests sold are consolidated up to the date of disposal. Balances between Group
companies are eliminated; no profit is taken on sales between Group companies. Goodwill arising on the acquisition of interests in
subsidiaries, representing the excess of consideration transferred over the Group's share of the fair values of identifiable assets, liabilities
and contingent liabilities acquired, is capitalised as a separate item.

An entity is treated as a joint venture where the Group holds a long term interest and shares control under a contractual agreement. In
the Group accounts, interests in joint ventures are accounted for using the proportionate consolidation method of accounting. The
consolidated income statement includes the Group’s share of the joint ventures’ turnover and includes the Group’s share of the operating
results, interest, pre-tax results and attributable taxation of such undertakings.

2.3 Judgements and estimates

The preparation of the consolidated financial statements requires management to make judgements, estimates and assumptions that
affect the application of policies and reported amounts of assets and liabilities, income and expenses. The estimates and associated
assumptions are based on historical experience and various other factors that are believed to be reasonable under the circumstances.
Actual results may differ from these estimates. 

The estimates and underlying assumptions are reviewed on an on-going basis. Revisions to accounting estimates are recognised in
accordance with IAS 8 ‘Accounting Policies, Changes in Accounting Estimates and Errors’. Critical judgements, estimates and
assumptions that are applied in the preparation of the consolidated financial statements include:

Depreciation and amortisation

The Group exercises judgement to determine useful lives and residual values of intangibles, computer equipment, and fixtures, fittings
and equipment. The assets are depreciated down to their residual values over their estimated useful lives.

Impairment

The value in use calculation uses cash flow projections based on financial forecasts for the next two years approved by management
covering the lower of useful economic life and extrapolated for a 15 year period. In each case it is assumed there will be no growth 
beyond 2015 and the cash flows of each acquisition are discounted at a rate of 10%, which approximates to the Group’s weighted average
cost of capital. 

28 Alliance Pharma plc | Annual Report 2013

Financial Statements

2. Summary of significant accounting policies continued

Provisions

Provisions have been made for onerous leases and associated costs (see note 24) and for slow moving and obsolete stock. These
provisions are estimates and the actual costs and timing of future cash flows are dependent on future events. The difference between
expectations and the actual future liability will be accounted for in the period when such determination is made.

Deferred consideration

The Company determines that where there is an obligation to pay consideration dependent on the sale of a product, and the Company can
control whether the product is sold or not, the consideration is only recognised once a sale is made.

Consolidation of Joint Venture

The Group owns 60% of the issued share capital of Unigreg Limited. The Group considered the existence of substantive participating
rights held by the minority shareholder which provide that shareholder with a veto right over the significant financial and operating
policies of Unigreg Ltd and determined that, as a result of these rights, the Group does not have control over the financial and operating
policies of Unigreg Ltd, despite the Group's 60% ownership interests consequently the company is integrated with proportionate
consolidation.

2.4 Revenue recognition

Revenue comprises the fair value of the consideration received or receivable for the sale of goods in the ordinary course of the Group’s
activities. Revenue is shown net of value-added tax, estimated returns, rebates and discounts and after eliminating sales within the Group
and represents amounts invoiced to third parties in relation to the Group’s sole principle activity namely the distribution of
pharmaceutical products. Revenue is recognised when a Group entity has delivered products to the customer and confirmation of receipt
is confirmed. The risks and rewards are transferred upon customers receiving the goods.

2.5 Foreign currency transactions

The consolidated financial statements are presented in sterling, which is the presentational currency of the Group and the functional
currency of the parent Company. Foreign currency transactions by Group companies are booked at the exchange rate ruling on the date of
the transaction. Foreign currency monetary assets and liabilities are retranslated into local currency at the rate of exchange ruling at the
balance sheet date. Exchange differences are booked to the income statement.

2.6 Property, plant and equipment

Computer equipment, fixtures, fittings and equipment are stated at the cost of purchase less any provisions for depreciation and
impairment. The rates generally applicable are:

Computer equipment
Fixtures, fittings and equipment

20% – 33.3% per annum, straight line
20% – 25% per annum, straight line

Material residual value estimates are updated as required, but at least annually, whether or not the asset is revalued.

2.7 Leases

Leasing agreements which transfer to the Group substantially all the benefits and risks of ownership are treated as finance leases, as if
the asset had been purchased outright. The assets are included within computer equipment, fixtures, fittings and equipment and the
capital element of the leasing commitments are shown as obligations under finance leases. Assets held under finance leases are
depreciated on a basis consistent with similar owned assets or the lease term if shorter. The interest element of the lease rental is
included in the income statement. All other leases are considered operating leases and the annual rentals are included in the income
statement on a straight line basis over the lease term.

2.8 Goodwill

Goodwill represents the excess of the consideration transferred over the fair value of the Group's share of the identifiable net assets
acquired. Goodwill is reviewed for impairment at least annually by assessing the recoverable amount of each acquisition, considered to be
a cash-generating unit, to which the goodwill relates. The recoverable amount is the higher of fair value less costs to sell and value in
use. When the recoverable amount of the cash-generating unit is less than the carrying amount an impairment loss is recognised. Any
impairment is recognised immediately in the Group Income Statement and is not subsequently reversed. 

Alliance Pharma plc | Annual Report 2013

29

Notes to the Financial 
Statements continued
for year ended 31 December 2013

2. Summary of significant accounting policies continued

2.9 Intangible assets

Acquired intangible assets

Intangible assets are stated at the lower of cost less provision for amortisation and impairment or the recoverable amount (explained
further in note 10). Technical know-how and trademarks are deemed to have an indefinite useful life and are tested for impairment
annually. Distribution licences are amortised over the current life of the licence on a straight line basis and are tested for impairment
annually, if the licence period can be extended the useful life of the intangible asset shall include the renewal period only if there is
evidence to support renewal by the entity without disproportionate cost. In determining the useful economic life of distribution rights each
acquisition has been reviewed separately and consideration given to the period over which the Group expects to derive economic benefit.

Internally-generated intangible assets –Research and development expenditure

Research expenditure is charged to the Income Statement in the period in which it is incurred. Development expenditure is capitalised
when it can be reliably measured and the project it is attributable to is separately identifiable, is technically feasible, demonstrates future
economic benefit, and will be used or sold by the Group once completed. 

The capitalised cost is amortised over the period during which the Group is expected to benefit and begins when the asset is ready 
for use. 

Development costs are reviewed at least annually for impairment by assessing the recoverable amount of each cash-generating unit, to
which the development costs relate. The recoverable amount is the higher of fair value less costs to sell and value in use. When the
recoverable amount of the cash-generating unit is less than the carrying amount an impairment loss is recognised. Any impairment is
recognised immediately in the Group Income Statement. Any reversal of a previously recorded impairment loss in a subsequent period
would also be recognised immediately in the Group Income Statement and is not subsequently reversed. 

Development costs not meeting the recognition criteria are expensed as incurred.

Impairment

For the purposes of assessing impairment, assets are grouped at the lowest levels for which there are separately identifiable cash flows
(cash-generating units). As a result, some assets are tested individually for impairment and some are tested at cash-generating unit
level. Goodwill, other individual assets or cash-generating units that include goodwill, other intangible assets with an indefinite useful
life, and those intangible assets not yet available for use are tested for impairment at least annually.

An impairment loss is recognised for the amount by which the asset's or cash-generating unit's carrying amount exceeds its recoverable
amount. The recoverable amount is the higher of fair value, reflecting market conditions less costs to sell, and value in use based on an
internal discounted cash flow evaluation. Impairment losses recognised for cash-generating units, to which goodwill has been allocated,
are credited initially to the carrying amount of goodwill. Any remaining impairment loss is charged pro rata to the other assets in the cash
generating unit. With the exception of goodwill and development costs, all assets are subsequently reassessed for indications that an
impairment loss previously recognised may no longer exist.

2.10 Inventories

Inventories are included at the lower of cost less any provision for impairment or net realisable value. Cost is determined on a first-in-
first-out basis using the weighted average cost.

2.11 Taxation

The tax expense represents the sum of the tax currently payable and deferred tax.

The tax currently payable is based on the taxable profit for the year. Taxable profit differs from profit reported in the income statement
because the former excludes items of income or expense that are either taxable or deductible in other years or that are never taxable or
deductible, and it includes tax reliefs that are not included in the income statement. The Group’s liability for current tax is calculated
using tax rates that have been enacted or substantively enacted by the balance sheet date.

Deferred tax is the tax expected to be payable or recoverable on differences between the carrying amount of assets and liabilities in the
financial statements and the corresponding tax bases used in the computation of taxable profit, and is accounted for using the balance
sheet liability method. Deferred tax liabilities are provided in full on temporary differences, and deferred tax assets are recognised to the
extent that it is probable that future taxable profits will be available against which the temporary differences can be utilised. Deferred tax
is provided using the rates of tax that are expected to apply in the period when the liability is settled or the asset is realised, based on
rates that have been substantively enacted by the balance sheet date. Deferred tax assets and liabilities are not discounted. The Group
jointly controls the sharing of profits in the joint venture and as such no deferred tax has been recognised on temporary differences.

30 Alliance Pharma plc | Annual Report 2013

Financial Statements

2. Summary of significant accounting policies continued

2.12 Derivative financial instruments and hedging activities

Derivative financial instruments are used to manage exposure to market risk from treasury operations. The principal financial instrument
used by the Group is interest rate swaps. The Group does not hold or issue derivative financial instruments for trading or speculative
purposes. Derivative financial instruments are recognised in the balance sheet at fair value and then re-measured at subsequent
reporting dates. The fair value is calculated by reference to market interest rates and supported by counterparty confirmation.

The interest rate swaps are designated as cash flow hedges.

The effective portion of changes in the fair value of derivative financial instruments that are designated as cash flow hedges is recognised
in other comprehensive income, while the gain or loss relating to the ineffective portion is recognised immediately in the income
statement. Changes in the fair value of derivative financial instruments that are not designated as cash flow hedges are recognised in the
income statement as they arise.

2.13 Debt instruments

Debt instruments are initially stated at their fair value net of issue costs, and subsequently measured at amortised cost using the
effective interest rate method.

Convertible Unsecured Loan Stock issued by the Company is regarded as compound financial instruments. Compound financial
instruments are split and recorded respectively within each of its two components, equity and liability. The fair values of the liability
component and the equity conversion component were determined at issuance of the bond. The equity component was determined as nil
and the fair value of the liability component, included in long-term borrowings, was calculated using a market interest rate for an
equivalent non-convertible bond.

2.14 Trade payables

Trade payables are recognised initially at fair value and subsequently measured at amortised cost using the effective interest rate
method.

2.15 Financial assets – loans and receivables

Loans and receivables are non-derivative financial assets with fixed or determinable payments that are not quoted in an active market.
They are included in current assets, except for maturities greater than 12 months after the balance sheet date. These are classified as
non-current assets. The Group’s loans and receivables comprise ‘trade and other receivables’ and cash and cash equivalents in the
balance sheet (note 2.16 and 2.17).

2.16 Trade receivables

Trade receivables are recognised initially at fair value and subsequently measured at amortised cost using the effective interest method,
less provision for impairment. A provision for impairment of trade receivables is established when there is objective evidence that the
Group will not be able to collect amounts due according to the original terms of the receivables.

2.17 Cash and cash equivalents

For the purpose of the cash flow statement, cash and cash equivalents comprise cash on hand, deposits held at call with banks, other
short-term highly liquid investments, available with no penalty, with original maturities of three months or less, bank overdrafts and
working capital facilities.

2.18 Working capital facility

The terms of this arrangement are such that the risk and reward of ownership of the trade receivables do not pass to the finance provider.
As such the receivables are not de-recognised on funds drawdown against this facility. This facility is recognised as a liability for the
amount drawn.

Alliance Pharma plc | Annual Report 2013

31

Notes to the Financial 
Statements continued
for year ended 31 December 2013

2. Summary of significant accounting policies continued

2.19 Employee benefits – share-based compensation

The Group operates an equity-settled, share-based compensation plan. The fair value of the employee services received in exchange for
the grant of the options is recognised as an expense over the vesting period. The total amount to be expensed over the vesting period is
determined by reference to the fair value of the options granted. Non-market vesting conditions are included in assumptions about the
number of options that are expected to become exercisable. At each balance sheet date, the Group revises its estimates of the number of
options that are expected to become exercisable. It recognises the impact of the revision of original estimates, if any, in the Group Income
Statement, with a corresponding adjustment to equity. The proceeds received net of any directly attributable transaction costs are
credited to share capital (nominal value) and share premium when the options are exercised.

2.20 Equity

Equity comprises the following:

“Share capital” represents the nominal value of equity shares.

“Share premium” represents the excess over nominal value of the fair value of consideration received for equity shares, net of expenses
of the share issue.

“Share option reserve” represents equity-settled share-based employee remuneration until such share options are exercised.

“Other reserves” represents the fair value of derivative financial instruments at the balance sheet date that are designated as cash flow
hedges net of deferred tax, less amounts reclassified through other comprehensive income.

“Retained earnings” represents retained profit.

“Reverse takeover reserve” represents the difference between the fair value and nominal value of shares issued on a reverse takeover.

2.21 Investments

Investments in subsidiaries included in the Company’s balance sheet are stated at cost less any provision for impairment.

2.22 Provisions

Provisions are recognised when there is a present legal or constructive obligation as a result of a past event, for which it is probable that
a transfer of economic benefits will be required to settle the obligation and where a reliable estimate can be made of the amount of the
obligation.

Where material, the provisions have been discounted to their present value.

2.23 Business combinations

Business combinations are accounted for using the acquisition accounting method. Identifiable assets, liabilities and contingent liabilities
acquired are measured at fair value at acquisition date. The consideration transferred is measured at fair value and includes the fair value
of any contingent consideration. The costs of acquisition are charged to the income statement in the period in which they are incurred.

2.24 New standards not yet applied

A number of new EU adopted standards, amendments to standards and interpretations are not yet effective for the year ended 31
December 2013 and have not been applied in preparing these financial statements. The following list is not comprehensive but includes
the most significant to these financial statements:

l IFRS11 Joint Arrangements issued in May 2011 (effective date 1 January 2014) supersedes IAS31 Interests in Joint Ventures. The new
standard restricts the use of proportionate consolidation, currently used by the Group to account for its joint venture Unigreg Limited,
in favour of the equity method of accounting. This will affect the presentation of both the balance sheet and the income statement. The
results of Unigreg Limited will be brought into the accounts within one line on the income statement and the investment will be shown
as one line on the balance sheet rather than on a line by line basis.

l IFRS10 Consolidated financial Statements issued in May 2011 (effective date 1 January 2014) replaces IAS27 Consolidated and

Separate Financial Statements which has been renamed IAS27 Separate Financial Statements. 

l IFRS12 Disclosure of interests in other entities is a new disclosure standard issued in May 2011 and is effective from 1 January 2014.
The Group continually reviews amendments to the standards made under the IASB’s annual improvements project.

32 Alliance Pharma plc | Annual Report 2013

Financial Statements

3. Segmental reporting

Operating segments

An operating segment is defined as a component of the entity: 

i)

that engages in business activities from which it may earn revenues and incur expenses,

ii) whose operating results are regularly reviewed by the entity’s chief operating decision maker (CODM) to make decisions about the

resources to be allocated to the segment and assess its performance, and

iii) for which discrete financial information is available.

For the year ended 31 December 2013 the Executive Team has been identified as the CODM.

Our management information system produces reports for the Executive Team grouping financial performance under the following
business areas:

l Hydromol 
l Secondary Care
l Community and Consumer Products
l Established Products 
l International
All business areas are responsible for developing, marketing and distributing a range of pharmaceutical and other medical products. As
permitted by IFRS 8, since these business areas are deemed to have similar economic characteristics and are similar, if not the same, in
all of the following:

l business areas derive their revenue from the supply of pharmaceutical products,
l the production and distribution process is the same across all business areas,
l business areas supply to similar customers i.e. pharmaceutical distributors or pharmacies, and
l all business areas are subject to a similar regulatory environment.
The business areas have been aggregated into a single reportable segment, namely pharmaceuticals. Each month the CODM is
presented with financial information prepared in accordance with IFRS as adopted in the EU and the accounting policies set out in note 2
to these financial statements. As such the financial information provided to the CODM regarding the operating segment has already been
disclosed in the financial statements. 

Geographical information

The following revenue information is based on the geographical location of the customer:

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

United Kingdom                                                                                                                                                                        38,890                36,719
Ireland                                                                                                                                                                                          3,626                  4,288
China                                                                                                                                                                                               239                  2,475
Rest of the world                                                                                                                                                                         2,758                  1,415

                                                                                                                                                                                                   45,513                44,897

All non-current assets are located within the United Kingdom.

Alliance Pharma plc | Annual Report 2013

33

Notes to the Financial 
Statements continued
for year ended 31 December 2013

3. Segmental reporting continued

Major customers

During the year there were 2 (year ended 31 December 2012: 2) customers who separately comprised 10% or more of revenue.

                                                                                                                                                                                                                      Year ended
                                                                                                                                                                                                                        31 December
                                                                                                                                                                                                                                         2013
                                                                                                                                                                                                                               £000s

Major customer 1                                                                                                                                                                                                 15,252
Major customer 2                                                                                                                                                                                                 10,937

                                                                                                                                                                                                                               26,189

                                                                                                                                                                                                                       Year ended
                                                                                                                                                                                                                   31 December
                                                                                                                                                                                                                                  2012
                                                                                                                                                                                                                                £000s

Major customer 1                                                                                                                                                                                                 14,283
Major customer 2                                                                                                                                                                                                 10,097

                                                                                                                                                                                                                               24,380

4. Profit before taxation

Profit before taxation is stated after charging:

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Fees payable to the Company’s auditor for the audit of the Company’s annual accounts                                                          8                         8
Fees payable by the Group to the Company’s auditor for other services:
– The audit of the Company’s subsidiaries                                                                                                                                   38                       40
– Other advisory services                                                                                                                                                             112                       50
Amortisation of intangible assets                                                                                                                                                 422                     573 
Share options charge                                                                                                                                                                     632                     369
Depreciation of plant, property and equipment                                                                                                                          266                     274
Operating lease rentals                                                                                                                                                                   97                       97
Loss on foreign exchange transactions                                                                                                                                         72                       73

34 Alliance Pharma plc | Annual Report 2013

Financial Statements

5. Finance costs

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Interest payable and similar charges                                     

On loans and overdrafts                                                                                                                                                         (1,222)                (1,466)
Amortised finance issue costs                                                                                                                                                   (22)                     (26)
Notional interest                                                                                                                                                                          (37)                     (49)

                                                                                                                                                                                                   (1,281)                (1,541)

Interest income                                                                                                                                                                                   2                         -

Other finance charges                                                              

Foreign exchange movement on euro denominated debt                                                                                                       (72)                       30

                                                                                                                                                                                                        (72)                       30

Finance costs – net                                                                                                                                                                  (1,351)                (1,511)

Notional interest relates to the unwinding of the discount applied to provisions (see note 24).

6. Directors and employees

Employee benefit expenses for the Group during the period were as follows:

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Wages and salaries                                                                                                                                                                     4,691                  4,288
Social security costs                                                                                                                                                                      639                     566
Other pension costs (note 30)                                                                                                                                                       307                     306
Share-based employee remuneration (note 26)                                                                                                                          632                     369

                                                                                                                                                                                                     6,269                  5,529

The average number of employees of the Group during the period was:

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012

Management and administration                                                                                                                                                   72                       63

Remuneration in respect of Directors (including pension) was as follows:

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Emoluments                                                                                                                                                                                1,045                  1,014
Relocation expenses                                                                                                                                                                           -                         2

                                                                                                                                                                                                     1,045                  1,016

Gain on share options recognised by directors during the year was £212,920 (2012: £nil).
For additional disclosures please refer to Directors’ Remuneration section of the Directors’ Report.

Alliance Pharma plc | Annual Report 2013

35

Notes to the Financial 
Statements continued
for year ended 31 December 2013

6. Directors and employees continued

The amounts set out above include remuneration in respect of the highest paid Director as follows:

                                                                                                                                                                                                               Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Emoluments for qualifying services                                                                                                                                             265                     256

During the period contributions were paid to money purchase schemes for four directors (year ended 31 December 2012: four).

Key management of the Group are the Executive Team. Benefit expenses in respect of the key management was as follows:

                                                                                                                                                                                           Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Short term employee benefits                                                                                                                                                      986                     931
Share-based payments                                                                                                                                                                  121                     131
Post-employment benefits                                                                                                                                                              56                       55

                                                                                                                                                                                                     1,163                  1,117

Average number of members of the CODM (the Executive Team) for the year ended 31 December 2013 was four (year ended 31 
December 2012:4).

7. Taxation

Analysis of charge in period.

                                                                                                                                                                                                               Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

United Kingdom corporation tax at 23.25% (2012: 24.5%)                               

In respect of current period                                                                                                                                                     2,242                  1,910
Adjustment in respect of prior periods                                                                                                                                      106                         -

                                                                                                                                                                                                     2,348                  1,910
Deferred tax (see note 23)                                                        

Origination and reversal of temporary differences                                                                                                                     77                     209

Taxation                                                                                                                                                                                        2,425                  2,119

36 Alliance Pharma plc | Annual Report 2013

Financial Statements

7. Taxation continued

The difference between the total current tax shown above and the amount calculated by applying the standard rate of UK corporation tax
to the profit before tax is as follows:

                                                                                                                                                                                                               Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Profit on ordinary activities before tax                                                                                                                                    12,009                10,809
Profit on ordinary activities multiplied by standard rate of corporation 
tax in the United Kingdom of 23.25% (2012: 24.5%)                                                                                                                2,792                  2,648
Effect of:                                                                                     
Non-deductible expenses                                                                                                                                                              139                       21
Attributable to joint venture                                                                                                                                                          (11)                   (189)
Adjustment in respect of prior period                                                                                                                                          106                         -
Impact of reduction in UK tax rate on deferred tax liability                                                                                                     (597)                   (353)
Other differences                                                                                                                                                                             (4)                       (8)

Total taxation                                                                                                                                                                               2,425                  2,119

A number of changes to the UK Corporation tax system were announced in the Finance Act 2012. The main rate of corporation tax was
reduced from 24% to 23% from 1 April 2013. Further reductions to the main rate are proposed to reduce the rate by 2% per annum to 21%
from 1 April 2014 and will reduce by another 1% to 20% from 1 April 2015. At the balance sheet date the substantively enacted rate was
21% (2012: 23%). The further 1% reduction has not been substantively enacted at the balance sheet date and is therefore not included in
these financial statements.

The proposed reduction of the main rate of corporation tax by 1% from 1 April 2015 is expected to be enacted during 2014. The overall
effect of this change from 21% to 20%, if applied to the deferred tax balance at 31 December 2013, would be to decrease the deferred tax
liability by £300,000 (2012: £266,000).

8. Dividends

                                                                                                                                                                                 Year ended                                   Year ended
                                                                                                                                                             31 December                               31 December
                                                                                                                                                                             2013                                              2012
                                                                                                                                   Pence/share                £000s     Pence/share                 £000s

Amounts recognised as distributions to owners in the year                                                                                                            

Interim dividend for the prior financial year                                                                       0.275                     666                  0.250                     600

Final dividend for the prior financial year                                                                           0.550                 1,374                  0.500                  1,203

                                                                                                                                                                          2,040                                             1,803

Interim dividend for the current financial year                                                                  0.303                     800                  0.275                     666

The proposed final dividend of 0.605 per share for the current financial year was approved by the Board of Directors on 25 March 2014 and
is subject to the approval of shareholders at the Annual General Meeting. The proposed dividend has not been included as a liability as at
31 December 2013 in accordance with IAS 10 Events After the Balance Sheet Date. The interim dividend for the current financial year was
paid on 15 January 2014. Subject to shareholder approval, the final dividend will be paid on 10 July 2014 to shareholders who are on the
register of members on 13 June 2014.

Alliance Pharma plc | Annual Report 2013

37

Notes to the Financial 
Statements continued
for year ended 31 December 2013

9. Earnings per share (EPS)

Basic EPS is calculated by dividing the earnings attributable to ordinary shareholders by the weighted average number of ordinary shares
in issue during the year. For diluted EPS, the weighted average number of ordinary shares in issue is adjusted to assume conversion of all
dilutive potential ordinary shares. 

A reconciliation of the weighted average number of ordinary shares used in the measures is given below:

                                                                                                                                                                                                               Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012

For basic EPS calculation                                                                                                                                               250,836,337       240,881,464
Employee share options                                                                                                                                                      2,020,036           2,032,846
Conversion of Convertible Unsecured Loan Stock (CULS)                                                                                            12,154,481         20,053,595

For diluted EPS calculation                                                                                                                                            265,010,854       262,967,905

A reconciliation of the earnings used in the different measures is given below:

                                                                                                                                                                                                               Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    £000s                 £000s

Earnings for basic EPS                                                                                                                                                               9,584                  8,690

Interest saving on conversion of CULS                                                                                                                                        204                     337
Tax effect of interest saving on conversion of CULS                                                                                                                  (47)                     (81)

Earnings for diluted EPS                                                                                                                                                            9,741                  8,946

The resulting EPS measures are:

                                                                                                                                                                                                               Year ended        Year ended
                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
                                                                                                                                                                                                    Pence                Pence

Basic EPS                                                                                                                                                                                      3.82                    3.61

Diluted EPS                                                                                                                                                                                    3.68                    3.40

38 Alliance Pharma plc | Annual Report 2013

Financial Statements

10. Intangible assets

                                                                                                                                                                            Technical 
                                                                                                                                                                 know-how,
                                                                                                                                                                trademarks
                                                                                                                                                                              and
                                                                                                          Goodwill on         Purchased       distribution     Development
                                                                                                       consolidation            Goodwill                 rights                  costs                   Total
The Group                                                                                                  £000s                 £000s                 £000s                 £000s                 £000s

Cost                                                                                                                                                                             
At 1 January 2013                                                                                       1,144                  2,449                78,107                     310                82,010
Additions                                                                                                             -                         -                  9,534                       63                  9,597
Disposals                                                                                                            -                         -                       (4)                         -                       (4)

At 31 December 2013                                                                                1,144                   2,449                 87,637                       373                 91,603

Amortisation and impairment                                                                                                                                 
At 1 January 2013                                                                                               -                         -                  2,120                         -                  2,120
Amortisation for the year                                                                                  -                         -                     422                         -                     422

At 31 December 2013                                                                                        -                            -                   2,542                            -                   2,542

Net book amount                                                                                                                                                                
At 31 December 2013                                                                                1,144                   2,449                 85,095                       373                 89,061

At 1 January 2013                                                                                       1,144                  2,449                75,987                     310                79,890

Goodwill on consolidation

The goodwill on consolidation arose on the acquisition of Dermapharm Ltd, which took place during the year ended 29 February 2004. 

Purchased goodwill

During the year ended 31 December 2010, the Group completed the purchase of the trade and certain assets of Cambridge Laboratories
(Ireland) Limited and Cambridge Laboratories Limited. The goodwill of £0.6m that arose on acquisition reflects Alliance’s entry into the
oncology market with an established brand name and sales force. 

Goodwill of £1.85m arose on acquisition of Opus Group Holdings Limited in the year ended 31 December 2012.

Technical know-how, trademarks and distribution rights

Acquired trademarks and distribution rights when purchased are assessed to ensure they meet a set of criteria including an established
and stable sales history. The products are generally in niche areas where there is limited foreseeable prospect of erosion of sales and
they require little or no promotion to maintain sales. 

The following acquisition activities took place in the year:

l On 6 June 2013, the Group acquired all existing rights to Syntometrine from Novartis AG and Novartis Pharma AG (together "Novartis")

for a consideration of US$11.5 million. Alliance already owned the UK rights to Syntometrine, but Novartis and its affiliates ("the
Novartis Group") had been selling Syntometrine in a number of countries worldwide including Australia, South Africa, Malaysia and
New Zealand. In the 12 months to March 2013 the total sales of Syntometrine by the Novartis Group were US$3.2 million and the gross
margin generated was US$2.8 million. Alliance expects to have annual distribution and operating costs of approximately £0.5 million
associated with these new territories.

l On 18 December 2013, the Group acquired all UK and Republic of Ireland rights to Lypsyl from Novartis AG for a consideration of
US$3.0 million. In the 12 months to September 2013, total sales of Lypsyl by the Novartis Group were £1.2 million and the gross
margin generated was £0.5 million. Alliance intends to reinvest a proportion of the gross margin in marketing activity to promote 
the brand.

The consideration value for the Syntometrine and Lypsyl acquisitions was payable on completion. The acquisitions were funded from
available cash and existing facilities. £25 million was undrawn on the Group’s acquisition facilities at year end.

Alliance Pharma plc | Annual Report 2013

39

Notes to the Financial 
Statements continued
for year ended 31 December 2013

10. Intangible assets continued

Impairment

As explained in note 2.8 and 2.9 all intangible assets are stated at the lower of cost less provision for amortisation and impairment or the
recoverable amount. 

Goodwill (allocated across cash-generating units that are expected to benefit from it), indefinite life assets and development costs are
tested for impairment annually, or more frequently if there are indications that amounts might be impaired. The impairment test involves
determining the recoverable amount of the relevant asset or cash-generating unit, which corresponds to the higher of the fair value less
costs to sell or its value in use.

The value in use calculation considers each asset or cash generating unit on a case by case basis and uses cash flow projections based
on financial forecasts for the next two years, which are based on historic sales trends and management’s sales growth assumptions.
These forecasts are approved by management covering the lower of useful economic life and extrapolated for a 15 year period. 

The key assumptions on which cash flow projections are made are:

l There will be no growth beyond 2015;
l Cash flows are discounted at an appropriate rate. The discount rates consider market information and specific circumstances of each

asset or cash-generating unit. A rate of 10%, which approximates to the Group’s weighted average cost of capital, is considered
appropriate for all assets; and 

l The CODM considers 15 years to be a sufficient period to represent the indefinite useful economic lives of the products. 
The value in use calculations for all assets and cash generating units, when tested with assumptions beyond a reasonable range, did not
result in the recoverable amounts falling below their carrying amounts.

Development projects are reviewed as to the likelihood of their completion and valued using a discounted cash flow, using appropriate
risk factors, to assess whether the project is impaired. 

Unigreg Ltd, the joint venture company of which the Group holds 60%, has applied to China’s State Food and Drug Administration (‘SFDA’)
to vary the licence for importing Forceval into China. There is uncertainty about whether or when this variation will be approved. There is a
risk that for a period of time Unigreg will be unable to import further product into China. There are a number of measures of mitigation
that can be taken to offset this risk. The Board’s view is that these mitigation measures are likely to be sufficient to ensure the
continuation of the business in the long term, and that the intangible asset relating to Forceval in China is unlikely to be impaired. The
carrying value of the related intangible asset is £1.95m.

A new generic substitution and reference pricing regime is in the process of being implemented in the Republic of Ireland. This is
expected to adversely impact Nu-Seals sales, and may occur later this year. The Board’s view is that this impact will not be sufficiently
great as to cause the related intangible asset of £9.1m to be impaired. The recoverable amount, based on value in use, is estimated at
£9.7m. The key assumptions in arriving at the value in use are that the Nu-Seals’ volumes will fall by around 8%, that pricing will reduce
by 50% and that these impacts will be felt from Quarter 4 2014. The intangible asset could be impaired if volumes fell by more than 18%,
or if pricing fell by more than 53%.

                                                                                                                                                                            Technical 
                                                                                                                                                                 know-how,
                                                                                                                                                                trademarks
                                                                                                                                                                              and
                                                                                                          Goodwill on         Purchased       distribution     Development
                                                                                                       consolidation            Goodwill                 rights                  costs                   Total
The Group                                                                                                  £000s                 £000s                 £000s                 £000s                 £000s

Cost                                                                                                                                                                             
At 1 January 2012                                                                                       1,144                     600                65,730                     203                67,677
Additions                                                                                                             -                  1,849                12,377                     107                14,333

At 31 December 2012                                                                                 1,144                  2,449                78,107                     310                82,010

Amortisation and impairment                                                                                                                                 
At 1 January 2012                                                                                               -                         -                  1,547                         -                  1,547
Amortisation for the year                                                                                  -                         -                     573                         -                     573

At 31 December 2012                                                                                         -                         -                  2,120                         -                  2,120

Net book amount                                                                                                                                                       
At 31 December 2012                                                                                 1,144                  2,449                75,987                     310                79,890

At 1 January 2012                                                                                       1,144                     600                64,183                     203                66,130

40 Alliance Pharma plc | Annual Report 2013

Financial Statements

10. Intangible assets continued

                                                                                                                                                                    Technical 
                                                                                                                                                                 know-how,
                                                                                                                                                                trademarks
                                                                                                                                                                              and
                                                                                                          Goodwill on         Purchased       distribution     Development
                                                                                                       consolidation            Goodwill                 rights                  costs                   Total
The Group                                                                                                  £000s                 £000s                 £000s                 £000s                 £000s

Cost                                                                                                                                                                             
At 1 January 2011                                                                                       1,144                     600                59,355                         -                61,099
Additions                                                                                                             -                         -                  6,475                     203                  6,678
Disposals                                                                                                            -                         -                   (100)                         -                   (100)

At 31 December 2011                                                                                 1,144                     600                65,730                     203                67,677

Amortisation and impairment                                                                                                                                 
At 1 January 2011                                                                                               -                         -                     812                         -                     812
Amortisation for the year                                                                                  -                         -                     735                         -                     735

At 31 December 2011                                                                                         -                         -                  1,547                         -                  1,547

Net book amount                                                                                                                                                       
At 31 December 2011                                                                                 1,144                     600                64,183                     203                66,130

At 1 January 2011                                                                                       1,144                     600                58,543                         -                60,287

11. Property, plant and equipment

                                                                                                                                                                                                Fixtures,                           
                                                                                                                                                                   Computer        fittings and                           
                                                                                                                                                                  equipment         equipment                   Total
The Group                                                                                                                                                        £000s                 £000s                 £000s

Cost                                                                                                                       
At 1 January 2013                                                                                                                                                222                     952                  1,174
Additions                                                                                                                                                               257                       41                     298
Disposals                                                                                                                                                                  -                       (4)                       (4)

At 31 December 2013                                                                                                                                         479                       989                   1,468

Depreciation                                                                                                                                                                                                                    
At 1 January 2013                                                                                                                                                143                     467                     610
Provided in the year                                                                                                                                               68                     198                     266

At 31 December 2013                                                                                                                                         211                       665                       876

Net book amount                                                                                                                                                                                                            
At 31 December 2013                                                                                                                                         268                       324                       592

At 1 January 2013                                                                                                                                                  79                     485                     564

The net book amount held under finance leases was £nil (year ended 31 December 2012: £nil, year ended 1 January 2012: £1,000).

Alliance Pharma plc | Annual Report 2013

41

Notes to the Financial 
Statements continued
for year ended 31 December 2013

11. Property, plant and equipment continued

                                                                                                                                                                                                Fixtures,                           
                                                                                                                                                                   Computer        fittings and                           
                                                                                                                                                                  equipment         equipment                   Total
The Group                                                                                                                                                        £000s                 £000s                 £000s

Cost                                                                                                                       
At 1 January 2012                                                                                                                                                271                     902                  1,173
Additions                                                                                                                                                                 18                       55                       73
Disposals                                                                                                                                                              (67)                       (5)                     (72)

At 31 December 2012                                                                                                                                          222                     952                  1,174

Depreciation                                                                                                        
At 1 January 2012                                                                                                                                                127                     281                     408
Provided in the year                                                                                                                                               83                     191                     274
Eliminated on disposals                                                                                                                                     (67)                       (5)                     (72)

At 31 December 2012                                                                                                                                          143                     467                     610

Net book amount                                                                                                 
At 31 December 2012                                                                                                                                            79                     485                     564

At 1 January 2012                                                                                                                                                144                     621                     765

                                                                                                                                                                                                Fixtures,                           
                                                                                                                                                                   Computer        fittings and                           
                                                                                                                                                                  equipment         equipment                   Total
The Group                                                                                                                                                        £000s                 £000s                 £000s

Cost                                                                                                                       
At 1 January 2011                                                                                                                                                224                     890                  1,114
Additions                                                                                                                                                                 83                       57                     140 
Disposals                                                                                                                                                              (36)                     (45)                     (81)

At 31 December 2011                                                                                                                                          271                     902                  1,173

Depreciation                                                                                                        
At 1 January 2011                                                                                                                                                  84                     142                     226
Provided in the year                                                                                                                                               79                     184                     263
Eliminated on disposals                                                                                                                                     (36)                     (45)                     (81)

At 31 December 2011                                                                                                                                          127                     281                     408

Net book amount                                                                                                 
At 31 December 2011                                                                                                                                          144                     621                     765

At 1 January 2011                                                                                                                                                140                     748                     888

42 Alliance Pharma plc | Annual Report 2013

Financial Statements

12. Investments

                                                                                                                                                                                                                   Investment in
                                                                                                                                                                                                                        subsidiary
                                                                                                                                                                                                                   undertakings
The Company                                                                                                                                                                                                        £000s

Cost                                                                 
At 1 January 2013                                                                                                                                                                                                 37,618
Additions                                                                                                                                                                                                                  9,501

At 31 December 2013                                                                                                                                                                                          47,119

At 1 January 2012                                                                                                                                                                                                 36,402
Additions                                                                                                                                                                                                                  1,216

At 31 December 2012                                                                                                                                                                                           37,618

At 1 January 2011                                                                                                                                                                                                 32,260
Additions                                                                                                                                                                                                                  4,142

At 31 December 2011                                                                                                                                                                                           36,402

The additions in the year relate to the increased investment the company has made in its subsidiary to support the acquisition of new
product licenses and £20,902 to establish Alliance Pharmaceuticals SAS.

The subsidiary and associated undertakings where the Group held 20% or more of the equity share capital at 31 December 2013 
are shown below:

                                                                          Country of registration               Shares held             %                                                                       
Company                                                          or incorporation                          Class                        owned                Nature of business               

Alliance Pharmaceuticals Limited                United Kingdom                          Ordinary                   100                     Pharmaceutical sales
Dermapharm Limited                                     United Kingdom                          Ordinary                   100                     Dormant 
Alliance Health Limited                                  United Kingdom                          Ordinary                   100                     Dormant
Alliance Consumer Health Limited               United Kingdom                          Ordinary                   100                     Dormant
Alliance Generics Limited                              United Kingdom                          Ordinary                   100                     Dormant
Alliance Healthcare Limited                           United Kingdom                          Ordinary                   100                     Dormant
Caraderm Limited                                           Northern Ireland                         Ordinary                   100                     Dormant
Unigreg Limited                                               British Virgin Islands                  Ordinary                   60                       Pharmaceutical sales          
Unigreg Worldwide Limited                            United Kingdom                          Ordinary                   60                       Dormant
Opus Group Holdings Limited                        United Kingdom                          Ordinary                   100                     Dormant
Opus Healthcare Limited                                United Kingdom                          Ordinary                   100                     Dormant
Opus Healthcare Limited                                Republic of Ireland                      Ordinary                   100                     Non-trading
Alliance Pharmaceuticals GmbH                  Germany                                      Ordinary                   100                     Non-trading
Alliance Pharmaceuticals SAS                      France                                          Ordinary                   100                     Pharmaceutical sales

All subsidiary undertakings prepare accounts to 31 December, except Opus Healthcare Limited (Republic of Ireland) which prepares
accounts to 28 February and Unigreg Worldwide Limited which prepares accounts to 31 May. Alliance Pharmaceuticals Limited, Alliance
Pharmaceuticals GmbH and Alliance Pharmaceuticals SAS are the only investments held directly by Alliance Pharma plc. All other
investments are held by Alliance Pharmaceuticals Limited with the exception of Opus subsidiaries which are held by Opus Group Holdings
Limited and Unigreg Worldwide Limited which is held by Unigreg Limited.

Alliance Pharma plc | Annual Report 2013

43

Notes to the Financial 
Statements continued
for year ended 31 December 2013

13. Inventories

                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                             2013                   2012                   2012
The Group                                                                                                                                                        £000s                 £000s                 £000s

Finished goods and materials                                                                                                                        5,468                  5,393                  5,652

Inventory costs expensed through the income statement during the year were £15,945,000 (year ended 31 December 2012: £17,062,000,
year ended 1 January 2012: £18,423,000). During the year £157,217 (2012: £41,000) was recognised as an expense relating to the write-
down of inventory to net realisable value.

14. Trade and other receivables

                                                                                                                           The Group                                                                  The Company
                                                                            31 December    31 December          1 January    31 December    31 December          1 January
                                                                                           2013                   2012                   2012                   2013                   2012                   2012
                                                                                         £000s                 £000s                 £000s                £000s                 £000s                 £000s

Trade receivables                                                            9,131                  9,583                  8,152                         -                         -                         -
Other receivables                                                                536                     212                     147                       38                10,011                  2,008
Prepayments and accrued income                                   804                     350                     331                       12                       10                       12
Amounts owed by joint venture                                           68                         -                       30                         -                         -                         -

                                                                                       10,539                10,145                  8,660                       50                10,021                  2,020

Dividends declared but not paid between Alliance Pharmaceuticals Limited and the Company of nil for the year ended 31 December 2013
(for the year ended 31 December 2012: £10m, for the year ended 31 December 2011: £2m) are included within other receivables.

The ageing of trade receivables at 31 December is detailed below:

                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                             2013                   2012                   2012
                                                                                                                                                                         £000s                 £000s                 £000s

Not past due                                                                                                                                                     4,292                  5,194                  3,858
Due 30-31 December*                                                                                                                                     3,994                  3,732                  3,289
Past due 3 days to 91 days                                                                                                                                 662                     569                     782
Past 91 days                                                                                                                                                         183                       88                     223

                                                                                                                                                                          9,131                  9,583                  8,152

* For the year ended 31 December 2013 £3,384,000 was received by the 10 January 2014. For the year ended 31 December 2012
£3,149,000 was received by the 11 January 2013. For the year ended 31 December 2011 £2,128,000 was received by the 13 January 2012. 

Trade and other receivables are stated net of estimated allowances for doubtful debts. As at 31 December 2013, trade and other
receivables of £108,000 (for the year ended 31 December 2012: £111,000) were past due and impaired.

Our policy requires customers to pay us in accordance with agreed payment terms. Depending on the geographical location, our
settlement terms are generally due within 30 or 60 days from the end of the month of sale and do not bear any effective interest rate.

15. Cash and cash equivalents

                                                                                                                           The Group                                                                  The Company
                                                                            31 December    31 December          1 January    31 December    31 December          1 January
                                                                                           2013                   2012                   2012                   2013                   2012                   2012
                                                                                         £000s                 £000s                 £000s                £000s                 £000s                 £000s

Cash at bank and in hand                                                  888                  4,634                  1,079                       12                     182                       77
Working capital facility                                                 (2,125)                       (1)                       (1)                         -                         -                         -

                                                                                       (1,237)                  4,633                  1,078                       12                     182                       77

44 Alliance Pharma plc | Annual Report 2013

Financial Statements

16. Major non-cash transactions

Principal non-cash transactions include finance issue costs amortised in the income statement during the year of £22,000 (year ended 31
December 2012: £26,000) and an exchange movement of £72,000 (year ended 31 December 2012: £30,000) (see note 5). Interest rate
swaps designated as cash flow hedges resulted in a £443,000 gain (year ended 31 December 2012: £6,000 gain) to other comprehensive
income. As a consequence of the onerous contracts a notional interest charge representing the unwinding of the discounted value of the
onerous contract provision of £37,000 (year ended 31 December 2012: £49,000) was recognised in the income statement. Amortisation of
intangible assets resulted in a charge of £422,000 (year ended 31 December 2012: £573,000) being recognised in the income statement. 

17. Trade and other payables – current

                                                                                                                           The Group                                                                  The Company
                                                                            31 December    31 December          1 January    31 December    31 December          1 January
                                                                                           2013                   2012                   2012                   2013                   2012                   2012
                                                                                         £000s                 £000s                 £000s                £000s                 £000s                 £000s

Trade payables                                                                 1,118                     902                  1,194                       19                         -                         -
Other taxes and social security costs                           1,123                  1,225                     864                         -                         -                         -
Accruals and deferred income                                       6,028                  7,019                  6,168                     190                     370                     321
Other payables                                                                    316                     940                     141                         -                       20                         -

                                                                                          8,585                10,086                  8,367                     209                     390                     321

18. Financial liabilities – borrowings

                                                                                                                           The Group                                                                  The Company
                                                                            31 December    31 December          1 January    31 December    31 December          1 January
                                                                                           2013                   2012                   2012                   2013                   2012                   2012
Current                                                                           £000s                 £000s                 £000s                £000s                 £000s                 £000s

Bank loans due within one year or on demand                                                                                                                                                            
Secured (a)                                                                       3,000                  6,250                  4,250                         -                         -                         -
Finance issue costs                                                         (105)                         -                         -                         -                         -                         -

                                                                                          2,895                  6,250                  4,250                         -                         -                         -

Convertible debt (note 19)                                                      -                  4,189                         -                         -                  4,189                         -

                                                                                          2,895                10,439                  4,250                         -                  4,189                         -

                                                                                                                           The Group                                                                  The Company
                                                                            31 December    31 December          1 January    31 December    31 December          1 January
                                                                                           2013                   2012                   2012                   2013                   2012                   2012
Current                                                                           £000s                 £000s                 £000s                £000s                 £000s                 £000s

Bank loans:                                                                                                                                                                                           
Secured (a)                                                                     21,250                20,225                15,225                         -                         -                         -
Finance issue costs                                                         (369)                         -                         -                         -                         -                         -

                                                                                       20,881                20,225                15,225                         -                         -                         -

Convertible debt (note 19)                                                      -                         -                  4,460                         -                         -                  4,460 

                                                                                       20,881                20,225                19,685                         -                         -                  4,460

(a) The bank loans are secured by a fixed and floating charge over the Company's and Group’s assets.

During the year £3.5m was drawn down on the revolving credit facility to fund acquisitions in the year.

In October 2013 the bank debt was repaid in full and new loans were drawn under new facilities provided by Lloyds Bank and Royal Bank
of Scotland.

Alliance Pharma plc | Annual Report 2013

45

Notes to the Financial 
Statements continued
for year ended 31 December 2013

19. Convertible debt

All outstanding convertible unsecured loan stock was converted into ordinary shares during 2013. The conversion rate was 21p per
ordinary share.

The Company received conversion notices in respect of £4,211,255 (year ended 31 December 2012: £296,750) nominal value of the
Company’s 8% Convertible Unsecured Loan Stock. Accordingly, the Company has allotted 20,053,570 ordinary shares of 1p each in 
the Company.

20. Other non-current liabilities

                                                                                                                           The Group                                                                  The Company
                                                                            31 December    31 December          1 January    31 December    31 December          1 January
                                                                                           2013                   2012                   2012                   2013                   2012                   2012
                                                                                         £000s                 £000s                 £000s                £000s                 £000s                 £000s

Deferred consideration for acquisitions                               -                       20                       40                         -                         -                         -

                                                                                                  -                       20                       40                         -                         -                         -

Deferred consideration of £nil (year ended 31 December 2012: £20,000, year ended 1 January 2012: £40,000) relates to the acquisition of
Dermapharm Limited which took place in the year ended 29 February 2004.

21. Financial instruments

The Group uses financial instruments comprising borrowings, some cash and liquid resources, and various items such as trade
receivables and trade payables that arise directly from its operations. The main purpose of these financial instruments is to raise finance
for the Group’s operations.

The Group also has a bank facility denominated in euros. The purpose of this facility is to manage the currency risk arising from the
Group's operations. The main risks arising from the Group’s financial instruments are interest rate risk, foreign currency risk and liquidity
risk. The Board reviews and agrees policies for managing each of these risks and they are summarised below. These policies have
remained unchanged from the previous year.

Interest rate risk

The Group finances its operations through a mixture of debt and equity. 

The Group uses interest rate swaps to reduce the risk arising from changes in interest rates. These swaps are re-measured to fair value
at each period end by Lloyds Bank. The valuations are indicative values based on mid-market levels as at the close of business on the
balance sheet date.

The Group has in place interest rate swaps with a nominal value of £20m (year ended 31 December 2012: £nil, year ended 1 January 2012:
£8m) to convert the floating interest rate charge to a fixed rate interest charge.

The interest rate exposure of the financial liabilities of the Group at the period end was:

                                                                                                                                                                           Fixed             Floating                   Total
                                                                                                                                                                          £000s                 £000s                 £000s

At 31 December 2013                                                                                                                    
Bank loans – sterling denominated                                                                                                                       -                24,250                24,250
Interest rate hedges                                                                                                                                       20,000              (20,000)                         -

Sterling subtotal                                                                                                                                            20,000                   4,250                 24,250

Working capital facility                                                                                                                                            -                  2,124                  2,124

Total financial liabilities                                                                                                                               20,000                   6,374                 26,374

Unamortised issue costs                                                                                                                                         -                   (474)                   (474)

Net book value of financial liabilities                                                                                                         20,000                   5,900                 25,900

46 Alliance Pharma plc | Annual Report 2013

Financial Statements

21. Financial instruments continued

                                                                                                                                                                           Fixed             Floating                   Total
                                                                                                                                                                          £000s                 £000s                 £000s

At 31 December 2012                                                                                                                            
Bank loans – sterling denominated                                                                                                                       -                26,475                26,475
Convertible loan stock                                                                                                                                      4,211                         -                  4,211

Sterling subtotal                                                                                                                                               4,211                26,475                30,686

Working capital facility – euro denominated                                                                                                         -                         1                         1

Euro subtotal                                                                                                                                                            -                         1                         1

Total financial liabilities                                                                                                                                   4,211                26,476                30,687

Unamortised issue costs                                                                                                                                    (22)                         -                     (22)

Net book value of financial liabilities                                                                                                              4,189                26,476                30,665

At 31 December 2011                                                                                                                    
Bank loans – sterling denominated                                                                                                                       -                19,475                19,475
Convertible loan stock                                                                                                                                      4,508                         -                  4,508
Interest rate hedges                                                                                                                                         8,000                (8,000)                         -

Sterling subtotal                                                                                                                                             12,508                11,475                23,983

Working capital facility – euro denominated                                                                                                         -                         1                         1

Euro subtotal                                                                                                                                                            -                         1                         1

Total financial liabilities                                                                                                                                 12,508                11,476                23,984

Unamortised issue costs                                                                                                                                    (48)                         -                     (48)

Net book value of financial liabilities                                                                                                            12,460                11,476                23,936

                                                                                                                                                                                       Fixed rate financial liabilities
                                                                                                                                                                                                                          Weighted
                                                                                                                                                                                               Weighted              average
                                                                                                                                                                                                 average          period for
                                                                                                                                                                                               fixed rate         which rate
                                                                                                                                                                                                            %               is fixed

At 31 December 2013                                                                                                                                                                                                                  
Sterling                                                                                                                                                                                          3.19          4.27 years

At 31 December 2012                                                                                                                                                                                                      
Sterling                                                                                                                                                                                           8.00          0.92 years

At 1 January 2012                                                                                                                                                                                                            
Sterling                                                                                                                                                                                           3.64          1.27 years

The Sterling floating rate borrowings bear interest at a rate based on LIBOR.

The Group balance sheet also includes financial assets in the form of cash at bank and in hand totalling £888,000 (31 December 2012:
£4,634,000, 1 January 2012: £1,079,000) which are exposed to floating interest rates based on LIBOR.

A 0.5% increase in LIBOR would reduce pre-tax profits by approximately £43,000 in 2014. A 0.5% decrease would have the opposite effect. 

Alliance Pharma plc | Annual Report 2013

47

Notes to the Financial 
Statements continued
for year ended 31 December 2013

21. Financial instruments continued

Currency risk

Approximately 9% of the Group's sales are to overseas customers in the EU. These sales are invoiced in euros. Certain expenses of the
Group are also in euros. The level of euro expenses broadly matches the level of euro income. Approximately 5% of the Group’s sales are
invoiced in other currencies.

All other Group sales and all but a small proportion of other Group expenses are denominated in sterling.

A 5% weakening of sterling against the euro would result in a £33,000 decrease in predicted pre-tax profits, while a 5% strengthening of
sterling would have the opposite effect.

Liquidity risk

The Group seeks to manage financial risk, to ensure sufficient liquidity is available to meet the identifiable needs of the Group and to invest
cash assets safely and profitably. The Group’s long-term funding is provided by bank loans with a repayment schedule of £750,000 per
quarter from December 2013. The existing bank facilities are due for renewal in June 2018. The Group’s policy is to re-finance the debt well
in advance of the term loan expiry. Short-term flexibility is achieved through the use of the £5,000,000 working capital facility.

Fair value measurement

Effective from 1 January 2013, the Group adopted the amendments to IFRS13 for financial instruments that are measured in the Group
balance sheet at fair value. This requires disclosure of fair value measurements by level of the following fair value measurement hierarchy:

l quoted prices (unadjusted) in active markets for identical assets or liabilities (Level 1);
l inputs other than quoted prices included within Level 1 that are observable for the asset or liability, either directly (that is, as prices) or

indirectly (that is, derived from prices) (Level 2); and

l inputs for the asset or liability that are not based on observable market data (that is, unobservable inputs) (Level 3).
Lloyds Bank performs valuations of financial items for financial reporting purposes. Valuation techniques are selected based on the
characteristics of each instrument, with the overall objective of maximising the use of market-base information. Valuation processes and
fair value changes are discussed among the audit committee and the finance team, who report to the Finance Director (FD) at least every
year, in line with the Group's reporting dates.

The valuation techniques used for instruments categorised in Level 2 are described below:

Interest rate swaps (Level 2)

The Group's interest rate swaps are not traded in active markets. These have been fair valued using observable interest rates. The effects
of non-observable inputs are not significant for interest rate swaps. 

The following table presents the Group’s financial assets and liabilities that are measured at fair value at 31 December 2013:

                                                                                                                                             Level 1               Level 2               Level 3                   Total
Assets                                                                                                                                    £000s                 £000s                 £000s                 £000s

Derivative financial instruments:                                                                                                  

Interest rate swaps                                                                                                                     -                       443                            -                       443

                                                                                                                                                       -                       443                            -                       443

The following table presents the Group’s financial assets and liabilities that are measured at fair value at 31 December 2012:

                                                                                                                                             Level 1               Level 2               Level 3                   Total
Liabilities                                                                                                                              £000s                 £000s                 £000s                 £000s

Derivative financial instruments:                                                                                                  

Interest rate swaps                                                                                                                     -                         -                         -                         -

                                                                                                                                                       -                         -                         -                         -

The following table presents the Group’s financial assets and liabilities that are measured at fair value at 1 January 2012:

                                                                                                                                             Level 1               Level 2               Level 3                   Total
Liabilities                                                                                                                              £000s                 £000s                 £000s                 £000s

Derivative financial instruments:                                                                                                  

Interest rate swaps                                                                                                                     -                         6                         -                         6

                                                                                                                                                       -                         6                         -                         6

48 Alliance Pharma plc | Annual Report 2013

Financial Statements

21. Financial instruments continued

The maturity profile of the Group's bank loans (capital only) at the year end is as follows:

                                                                                                                                                                                   At                          At                       At
                                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                             2013                   2012                   2012
                                                                                                                                                                         £000s                 £000s                 £000s

Due within:                                                                                                           

One year                                                                                                                                                            3,000                  6,250                  4,250

More than one year, not more than two years                                                                                              3,000                20,225                  5,000

More than two years, not more than three years                                                                                          3,000                         -                10,225

More than three years                                                                                                                                   15,250                         -                         -

                                                                                                                                                                        24,250                26,475                19,475

The maturity profile of the Group's financial gross liabilities (capital and interest) at the year end is as follows:

                                                                                                                                                                       31 December 2013
                                                                                                                                                In more than     In more than
                                                                                                                                                       one year,          two years,
                                                                                                                    In one year,     but not more     but not more     In more than
                                                                                                                              or less             than two             than five           five years                    Total
                                                                                                                                £000s                  £000s                  £000s                  £000s                  £000s

Trade and other payables                                                                          8,585                            -                            -                            -                   8,585
Working capital facility                                                                               2,125                            -                            -                            -                   2,125
Bank loans                                                                                                  3,737                   3,642                 19,436                            -                 26,815
Convertible loan stock                                                                                       -                            -                            -                            -                            -
Onerous contracts                                                                                         190                       199                            -                            -                       389

                                                                                                                  14,637                   3,841                 19,436                            -                 37,914

                                                                                                                                                        31 December 2012
                                                                                                                                   In more than     In more than
                                                                                                                                         one year,          two years,
                                                                                                          In one year,     but not more     but not more     In more than
                                                                                                                   or less            than two             than five           five years                   Total
                                                                                                                    £000s                 £000s                 £000s                 £000s                 £000s

Trade and other payables                                                                         10,086                       20                         -                         -                10,106
Working capital facility                                                                                      1                         -                         -                         -                         1
Bank loans                                                                                                  6,957                20,746                         -                         -                27,703
Convertible loan stock                                                                                4,436                         -                         -                         -                  4,436
Onerous contracts                                                                                         197                     182                     182                         -                     561

                                                                                                                   21,677                20,948                     182                         -                42,807

Alliance Pharma plc | Annual Report 2013

49

Notes to the Financial 
Statements continued
for year ended 31 December 2013

21. Financial instruments continued

                                                                                                                                                           1 January 2012
                                                                                                                                   In more than     In more than
                                                                                                                                         one year,          two years,
                                                                                                          In one year,     but not more     but not more     In more than
                                                                                                                   or less            than two             than five           five years                   Total
                                                                                                                    £000s                 £000s                 £000s                 £000s                 £000s

Trade and other payables                                                                           8,367                       20                       20                         -                  8,407
Working capital facility                                                                                      1                         -                         -                         -                         1
Bank loans                                                                                                  4,975                  5,546                10,519                         -                21,040
Derivative financial instruments                                                                      6                         -                         -                         -                         6
Convertible loan stock                                                                                   362                  4,748                         -                         -                  5,110
Onerous contracts                                                                                         189                     198                     420                         -                     807

                                                                                                                   13,900                10,512                10,959                         -                35,371

The maturity profile of the Company's financial gross liabilities (capital and interest) at the year end is as follows:

                                                                                           31 December 2013                   31 December 2012                         1 January 2012
                                                                                                                     Bank                                             Bank                                             Bank
                                                                                         Trade       borrowings                 Trade        borrowings                 Trade        borrowings
                                                                                   payables        other loans            payables           and other            payables           and other
                                                                                  and other                   loans           and other                  loans           and other                  loans
                                                                                         £000s                  £000s                 £000s                 £000s                 £000s                 £000s

In one year, or less                                                             209                         -                     390                  4,436                     321                     362
In more than one year, but not more than two                     -                         -                         -                         -                         -                  4,748
In more than two years, but not more than five                   -                         -                         -                         -                         -                         -
In more than five years                                                           -                         -                         -                         -                         -                         -

                                                                                             209                         -                     390                  4,436                     321                  5,110

The Group had £25,000,000 (31 December 2012: £11,499,000, 1 January 2012: £21,524,000) undrawn committed borrowing facilities
available at 31 December 2013 and £2,875,000 of working capital facility available.

Classification of the Group’s financial instruments is set out below:

                                                                                                                                                                                   Loans and   Non-financial
                                                                                                                                                                                receivables                 assets                    Total
As at 31 December 2013                                                                                                                                             £000s                  £000s                  £000s

Financial assets                                                                                                  
Cash                                                                                                                                                                             888                            -                       888
Trade and other receivables                                                                                                                                   9,734                       805                 10,539

                                                                                                                                                                                          10,622                       805                 11,427

50 Alliance Pharma plc | Annual Report 2013

Financial Statements

21. Financial instruments continued

                                                                                                                                                                                                                 Liabilities
                                                                                                                                                                                            Other          not within                              
                                                                                                                                                         Held for             financial              scope of
                                                                                                                                                           trading           liabilities                  IAS39                    Total
As at 31 December 2013                                                                                                               £000s                  £000s                  £000s                  £000s

Financial liabilities                                                                                                                        
Cash and cash equivalents                                                                                                          -                   2,125                            -                   2,125
Long term financial liabilities                                                                                                      -                 21,250                            -                 21,250
Convertible debt                                                                                                                            -                            -                            -                            -
Other liabilities                                                                                                                              -                            -                            -                            -
Financial liabilities                                                                                                                        -                   3,000                            -                   3,000
Trade and other payables                                                                                                             -                   7,462                   1,123                   8,585
Corporation tax                                                                                                                             -                            -                   1,154                   1,154
Onerous contracts – non current                                                                                                -                            -                       199                       199
Onerous contracts – current                                                                                                        -                            -                       190                       190

                                                                                                                                                               -                 33,837                   2,666                 36,503

                                                                                                                                                                  Loans and    Non-financial
                                                                                                                                                                 receivables                assets                   Total
As at 31 December 2012                                                                                                                                 £000s                 £000s                 £000s

Financial assets                                                                                                  
Cash                                                                                                                                                                   4,634                         -                  4,634
Trade and other receivables                                                                                                                            9,795                     350                10,145

                                                                                                                                                                         14,429                     350                14,779

                                                                                                                                                                                              Liabilities
                                                                                                                                                                          Other          not within                           
                                                                                                                                           Held for            financial             scope of
                                                                                                                                             trading            liabilities                 IAS39                   Total
As at 31 December 2012                                                                                                      £000s                 £000s                 £000s                 £000s

Financial liabilities                                                                                                                        
Cash and cash equivalents                                                                                                          -                         1                         -                         1
Long term financial liabilities                                                                                                      -                20,225                         -                20,225
Convertible debt                                                                                                                            -                  4,189                         -                  4,189
Other liabilities                                                                                                                              -                       20                         -                       20
Financial liabilities                                                                                                                        -                  6,250                         -                  6,250
Trade and other payables                                                                                                             -                  8,861                  1,225                10,086
Corporation tax                                                                                                                             -                         -                  1,322                  1,322
Onerous contracts – non current                                                                                                -                         -                     364                     364
Onerous contracts – current                                                                                                        -                         -                     197                     197

                                                                                                                                                       -                39,546                  3,108                42,654

Alliance Pharma plc | Annual Report 2013

51

Notes to the Financial 
Statements continued
for year ended 31 December 2013

21. Financial instruments continued

                                                                                                                                                                  Loans and    Non-financial
                                                                                                                                                                 receivables                assets                   Total
As at 1 January 2012                                                                                                                                       £000s                 £000s                 £000s

Financial assets                                                                                                  
Cash                                                                                                                                                                   1,079                         -                  1,079
Trade and other receivables                                                                                                                            8,329                     331                  8,660

                                                                                                                                                                           9,408                     331                  9,739

                                                                                                                                                                                              Liabilities
                                                                                                                                                                          Other          not within                           
                                                                                                                                           Held for            financial             scope of
                                                                                                                                             trading            liabilities                 IAS39                   Total
As at 1 January 2012                                                                                                            £000s                 £000s                 £000s                 £000s

Financial liabilities                                                                                                                        
Cash and cash equivalents                                                                                                          -                         1                         -                         1
Long term financial liabilities                                                                                                      -                15,225                         -                15,225
Convertible debt                                                                                                                            -                  4,460                         -                  4,460
Other liabilities                                                                                                                              -                       40                         -                       40
Financial liabilities                                                                                                                        -                  4,250                         -                  4,250
Trade and other payables                                                                                                             -                  7,503                     864                  8,367
Corporation tax                                                                                                                             -                         -                  1,046                  1,046
Onerous contracts – non current                                                                                                -                         -                     510                     510
Onerous contracts – current                                                                                                        -                         -                     189                     189
Derivative financial instruments - current                                                                                 6                         -                         -                         6

                                                                                                                                                       6                31,479                  2,609                34,094

Classification of the Company’s financial instruments is set out below:

                                                                                                                                                                                   Loans and   Non-financial
                                                                                                                                                                                receivables                 assets                    Total
As at 31 December 2013                                                                                                                                             £000s                  £000s                  £000s

Financial assets                                                                                                  
Cash                                                                                                                                                                        12                            -                         12
Trade and other receivables                                                                                                                                    -                         50                         50

                                                                                                                                                                                12                         50                         62

                                                                                                                                                                                                                 Liabilities
                                                                                                                                                                                            Other          not within                              
                                                                                                                                                                                      financial              scope of
                                                                                                                                                                                    liabilities                  IAS39                    Total
As at 31 December 2013                                                                                                                                             £000s                  £000s                  £000s

Financial liabilities                                                                                                                        
Convertible debt                                                                                                                                                       -                            -                            -
Trade and other payables                                                                                                                                     19                       190                       209
Corporation tax                                                                                                                                                        -                            -                            -

                                                                                                                                                                                19                       190                       209

52 Alliance Pharma plc | Annual Report 2013

Financial Statements

21. Financial instruments continued

                                                                                                                                                                                   Loans and    Non-financial
                                                                                                                                                                 receivables                assets                   Total
As at 31 December 2012                                                                                                                                 £000s                 £000s                 £000s

Financial assets                                                                                                  
Cash                                                                                                                                                                      182                         -                     182
Trade and other receivables                                                                                                                                    -                10,021                10,021

                                                                                                                                                                              182                10,021                10,203

                                                                                                                                                                                              Liabilities
                                                                                                                                                                          Other          not within                           
                                                                                                                                                                     financial             scope of
                                                                                                                                                                     liabilities                 IAS39                   Total
As at 31 December 2012                                                                                                                                 £000s                 £000s                 £000s

Financial liabilities                                                                                                                        
Convertible debt                                                                                                                                                4,189                         -                  4,189
Trade and other payables                                                                                                                                   390                         -                     390
Corporation Tax                                                                                                                                                        -                         4                         4

                                                                                                                                                                           4,579                         4                  4,583

                                                                                                                                                                                   Loans and    Non-financial
                                                                                                                                                                 receivables                assets                   Total
As at 1 January 2012                                                                                                                                       £000s                 £000s                 £000s

Financial assets                                                                                                  
Cash                                                                                                                                                                        77                         -                       77
Trade and other receivables                                                                                                                                    -                  2,020                  2,020

                                                                                                                                                                                77                  2,020                  2,097

                                                                                                                                                                                                     Other                           
                                                                                                                                                                                                financial
                                                                                                                                                                                                liabilities                   Total
As at 1 January 2012                                                                                                                                                                  £000s                 £000s

Financial liabilities                                                                                                                        
Convertible debt                                                                                                                                                                           4,460                  4,460
Trade and other payables                                                                                                                                                              321                     321

                                                                                                                                                                                                      4,781                  4,781

Alliance Pharma plc | Annual Report 2013

53

Notes to the Financial 
Statements continued
for year ended 31 December 2013

22. Derivative financial instruments

                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                            2013                   2012                   2012
                                                                                                                                                                        Assets          Liabilities          Liabilities
                                                                                                                                                                         £000s                 £000s                 £000s

Interest rate swap – cash flow hedge                                                                                                                443                         -                         6

                                                                                                                                                                              443                         -                         6

Current portion                                                                                                                                                        -                         -                         6
Non-current portion                                                                                                                                            443                         -                         -

The cash flow hedges were tested for effectiveness during the year and were found to be highly effective. The ineffective element was
immaterial. The hedge and interest on the bank debt are settled on a quarterly basis on the same date and measured against the same
benchmark, namely 3 month sterling LIBOR. The amount recognised through the income statement in respect of interest rate swaps
during the year was a charge of £105,000 (year ended 31 December 2012: £6,000 charge).

23. Deferred tax provision

                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                            2013                   2012                   2012
The Group                                                                                                                                                        £000s                 £000s                 £000s

Accelerated capital allowances                                                                                                                         (18)                       (4)                     (41)
Accelerated allowances on intangible assets                                                                                             (4,493)                (4,271)                (4,025)
Initial recognition of intangible from business combination                                                                     (1,690)                (1,849)                         -
Interest rate hedge                                                                                                                                             (93)                         -                         2

                                                                                                                                                                        (6,294)                (6,124)                (4,064)

Deferred tax asset                                                                                                                                                    -                         -                         -

Deferred tax provision                                                                                                                                   (6,294)                (6,124)                (4,064)

Reconciliation of deferred tax movements:

                                                                                                                                      Recognised                                                                                          
                                                                                                                                                           in other         Recognised         Recognised                              
                                                                                                                    31 December  comprehensive     in the income        on business     31 December
                                                                                                                                   2012                 income           statement        combination                     2013
The Group                                                                                                              £000s                   £000s                   £000s                   £000s                   £000s

Non-current assets                                                                                                                                                   

Intangible assets                                                                                    (4,271)                         -                   (222)                         -               (4,493)
Initial recognition of intangible from
business combination                                                                            (1,849)                         -                     159                         -               (1,690)
Property, plant and equipment                                                                    (4)                         -                     (14)                         -                    (18)

Current Liabilities                                                                                                                                                      

Derivative financial instruments                                                                     -                     (93)                         -                         -                    (93)

                                                                                                                   (6,124)                     (93)                     (77)                         -               (6,294)

Recognised as:                                                                                                                                                           

Deferred tax asset                                                                                            -                                                                                                          -

Deferred tax liability                                                                               (6,124)                                                                                                (6,294)

54 Alliance Pharma plc | Annual Report 2013

Financial Statements

23. Deferred tax provision continued

The Finance Act 2012 included legislation to reduce the main rate of corporation tax from 24% to 23% from 1 April 2013. The reduction
from 24% to 23% was substantively enacted at the balance sheet date and has therefore been reflected in these Group financial
statements.

In addition to the changes in the rates of corporation tax disclosed above, it was announced in the December 2012 Budget Statement that
the rate would be reduced from 23% to 21% from 1 April 2014 and in the March 2013 Budget Statement it was announced that the rate
would be further reduced to 20% from 1 April 2015.

At the balance sheet date the substantively enacted rate was 21% (2012: 23%). The further 1% reduction (to 20%) has not been
substantively enacted at the balance sheet date and is therefore not included in these financial statements. The overall effect of these
changes, if applied to the deferred tax balance at the balance sheet date, would be to reduce the deferred tax liability by £300,000 (2012:
£266,000). Deferred tax has been calculated at the prevailing rate of 21% (2012: 23% and 2011: 25%).

                                                                                                                                      Recognised                                                                                          
                                                                                                                                                           in other         Recognised         Recognised                              
                                                                                                                          1 January  comprehensive     in the income        on business      31 December 
                                                                                                                                   2012                 income           statement        combination                     2012
The Group                                                                                                              £000s                   £000s                   £000s                   £000s                   £000s

Non-current assets                                                                                                                                                   

Intangible assets                                                                                    (4,025)                         -                   (246)                         -                (4,271)
Initial recognition of intangible from
business combination                                                                                      -                                                    -                (1,849)                (1,849)
Property, plant and equipment                                                                  (41)                         -                       37                         -                       (4)

Current Liabilities                                                                                                                                                      

Derivative financial instruments                                                                    2                       (2)                         -                         -                         -

                                                                                                                   (4,064)                       (2)                   (209)                (1,849)                (6,124)

Recognised as:                                                                                                                                                           

Deferred tax asset                                                                                            -                                                                                                          -

Deferred tax liability                                                                               (4,064)                                                                                                 (6,124)

Alliance Pharma plc | Annual Report 2013

55

Notes to the Financial 
Statements continued
for year ended 31 December 2013

24. Provisions for other liabilities

                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                            2013                   2012                   2012
                                                                                                                                                                         £000s                 £000s                 £000s

At start of year                                                                                                                                                     561                     699                  1,013
Amount provided for in year                                                                                                                                    -                         -                         -
Amount utilised in year                                                                                                                                    (209)                   (187)                   (378)
Unwinding of discount                                                                                                                                          37                       49                       64

At year end                                                                                                                                                           389                     561                     699

Leases and associated costs for offices in Newcastle and Dublin, acquired as part of the Cambridge Laboratories acquisition have
subsequently been treated as onerous contracts. As at 31 December 2013 an amount of £389,000 (year ended 31 December 2012:
£561,000) discounted at a rate of 10%, representing payments due until the end of each contract has been recognised. The Dublin
property lease expired in 2011 and the Newcastle property lease will run until 2015. 

The balances are analysed as follows:

                                                                                                                                                             31 December    31 December          1 January
                                                                                                                                                                            2013                   2012                   2012
                                                                                                                                                                         £000s                 £000s                 £000s

Current                                                                                                                                                                 190                     197                     189
Non-Current                                                                                                                                                        199                     364                     510

25. Share capital

                                                                                                                                                                                            Authorised        Authorised
                                                                                                                                                                                        No. of shares                 £000s

At 31 December 2013 – ordinary shares of 1p each                                                                                                   400,000,000                   4,000
At 31 December 2012 – ordinary shares of 1p each                                                                                                      400,000,000                  4,000
At 1 January 2012 – ordinary shares of 1p each                                                                                                            400,000,000                  4,000

                                                                                                                                                                                                 Allotted,             Allotted,
                                                                                                                                                                                             called and         called and
                                                                                                                                                                                                fully paid            fully paid
                                                                                                                                                                                        No. of shares                 £000s

At 1 January 2012 – ordinary shares of 1p each                                                                                                            240,067,284                  2,401
Issued during the year                                                                                                                                                         2,968,358                       29

At 31 December 2012 – ordinary shares of 1p each                                                                                                      243,035,642                  2,430

Issued during the year                                                                                                                                                       21,045,231                     211

At 31 December 2013 – ordinary shares of 1p each                                                                                                   264,080,873                   2,641

Between 1 January 2013 and 31 December 2013, 991,661 shares were issued on the exercise of employee share options (2012: 1,555,265).

During the year, the Company received conversion notices in respect of £4,211,255 nominal value of the Company’s 8% Convertible
Unsecured Loan Stock (2012: £296,750). Accordingly, the Company has allotted 20,053,570 ordinary shares of 1p each in the Company
(2012: 1,413,093).

56 Alliance Pharma plc | Annual Report 2013

Financial Statements

25. Share capital continued

Potential issues of ordinary shares

Under the Group's share option scheme for employees and Directors options have been granted to subscribe for shares in the Company
at prices ranging from 7.75p to 37.25p. Options are exercisable three years after date of grant, but in certain instances this can be
extended to five years. Options outstanding are as follows:

                                                                                                                Exercise                               31 December    31 December          1 January
                                                                                                                      price             Exercise                   2013                   2012                   2012
Year of grant                                                                                              pence                   from            Number             Number             Number

2005                                                                                                              19.00                   2008                 9,000                  9,000                  9,000
2006                                                                                                              18.75                   2009               40,250                40,250                40,250
2007                                                                                                                9.25                   2010               33,250                33,250                33,250
2008                                                                                                                  8.5                   2011             644,750           1,308,426           1,419,526
2009                                                                                                                7.75                   2012             709,060           1,037,045           2,481,210
2010                                                                                            33.25 and 34.25                   2013          2,482,139           2,633,889           2,633,889
2011                                                                                            34.12 and 31.00                   2014          4,030,261           4,248,253           4,248,253
2012                                                                                                              29.25                   2015          3,250,600           3,494,826                         -
2013                                                                                            37.25 and 35.75                   2016          5,228,976                         -                         -
2013                                                                                                              35.75                   2018          4,000,000                         -                         -

                                                                                                                                                                 20,428,286         12,804,939         10,865,378

See Note 19 for details of the Convertible Unsecured Loan Stock.

Managing Capital

Our objective in managing the business’ capital structure is to ensure that the Group has the financial capacity, liquidity and flexibility to
support the existing business and to fund acquisition opportunities as they arise.

The capital structure of the Group consists of net bank debt and Shareholders’ equity. At 31 December 2013, net bank debt was £25.0
million, whilst Shareholders’ equity was £64.7 million.

The business is profitable and cash generative. The main financial covenants applying to bank debt are that leverage (the ratio of net bank
debt to EBITDA) should not exceed 2.5 times, interest cover (the ratio of EBITDA to finance charges) should be no less than 4.0 times, and
operating cash flows must exceed debt service cash flows. The Group comfortably complied with these covenants in 2013 and 2012.

Smaller acquisitions are typically financed purely with bank debt, while larger acquisitions typically involve a combination of bank debt
and additional equity. The mixture of debt and equity is varied, taking into account the desire to maximise the shareholder returns while
keeping gearing at comfortable levels, i.e. net bank debt below around two times EBITDA.

Alliance Pharma plc | Annual Report 2013

57

Notes to the Financial 
Statements continued
for year ended 31 December 2013

26. Share based payments

Under the Group's share option scheme for employees and Directors, options to subscribe for shares in the Company are granted
normally once each year. Options are granted with a fixed exercise price equal to the market price of the shares under option at the date
of grant. The contractual life of an option is 10 years from date of grant. Generally, options granted become exercisable on the third
anniversary of the date of grant, but in certain instances this can be extended to five years. Exercise of an option is normally subject to
continued employment. All share-based employee remuneration is settled in equity. Options are valued using the Black-Scholes option-
pricing model. There are generally no performance conditions attached to the options, but 4m of the options granted on 23 October 2013
are subject to performance criteria and have the extension to five years before they can be exercised. The assumptions used in the
calculation are as follows:

                                                                                                                                                                     Number                                                      
                                                                                                                                                                   of options
                                                                                                                                       Number of     remaining at                                                      
                                                                                Share price             Exercise              options    31 December           Expected            Risk free
Grant date                                                                    at issue                  price              granted                   2013             volatility                    rate 

27/07/05                                                                          19.00p                19.00p              424,516                 9,000                 22.8%                 4.13%
04/05/06                                                                          18.75p                18.75p              901,190               40,250                 14.9%                 4.30%
02/05/07                                                                            9.25p                  9.25p           1,402,425               33,250                 20.4%                 4.62%
23/04/08                                                                            8.50p                  8.50p           5,419,950             644,750                 18.6%                 4.90%
14/04/09                                                                            7.75p                  7.75p           2,307,860             709,060                 25.5%                 4.08% 
26/03/10                                                                          33.25p                33.25p           1,300,000          1,300,000                 43.5%                 3.90%
29/04/10                                                                          34.25p                34.25p           1,502,778          1,182,139                 45.7%                 3.90%
28/04/11                                                                          34.12p                34.12p           3,981,916          3,730,261                 43.9%                 4.10%
21/09/11                                                                          31.00p                31.00p              300,000             300,000                 53.2%                 4.10%
19/10/12                                                                          29.25p                29.25p           3,494,826          3,250,600                 49.7%                 1.70% 
06/06/13                                                                          37.25p                37.25p           3,370,703          3,328,976                 49.8%                 2.40%
23/10/13                                                                          35.75p                35.75p           5,900,000          5,900,000                 49.5%                 2.60%

In each case, it is assumed the majority of options will be exercised at the earliest opportunity and that on average they are exercised one
year after they become exercisable. The expected volatility is based on historical volatility from 23 December 2003. The risk free rate of
return is based on UK government bonds of a term consistent with the assumed option life.

Share options and weighted average exercise price are as follows for the reporting periods presented:

                                                                                                       2013                                              2012                                              2011
                                                                                                             Weighted                                      Weighted                                      Weighted
                                                                                                                average                                        average                                        average
                                                                                                               exercise                                        exercise                                        exercise
                                                                                                                     price                                             price                                             price
                                                                                     Number                Pence             Number                Pence             Number                Pence

Outstanding at start of year                                  12,804,939                 27.77         10,865,378                  24.82           8,741,125                  16.59

Granted                                                                     9,270,703                 36.30           3,494,826                  29.25           4,281,916                  33.90
Exercised                                                                   (991,661)                    8.24         (1,555,265)                  10.54         (2,089,250)                    8.70
Forfeited                                                                    (655,695)                 32.54                         -                         -              (68,413)                         -

Outstanding at end of year                                    20,428,286                 32.43         12,804,939                  27.77         10,865,378                  24.82

Exercisable at end of year                                       3,918,449                 16.79           2,427,971                    8.40           1,502,026                    8.89

Share options were exercised throughout the financial year. Share options were exercised between 31.75 and 36.50 pence per share. 

58 Alliance Pharma plc | Annual Report 2013

Financial Statements

27. Cash generated from operations

                                                                                                                                                                       Group                                           Company
                                                                                                                                     Year ended        Year ended       Year ended        Year ended
                                                                                                                                  31 December    31 December    31 December    31 December
                                                                                                                                                 2013                   2012                   2013                   2012
                                                                                                                                              £000s                 £000s                £000s                 £000s

Result for the period before tax                                                                                         12,009                10,809                     848                10,494 
Interest paid                                                                                                                           1,281                  1,466                     171                     352
Interest income                                                                                                                          (2)                         -               (1,464)                (1,310)
Other finance costs                                                                                                                    72                       45                         -                       26
Depreciation of property, plant and equipment                                                                    266                     274                         -                         - 
Amortisation of intangibles                                                                                                     422                     573                         -                         -
Change in inventories                                                                                                              (75)                     505                         -                         -
Change in trade and other receivables                                                                                (394)                   (724)                    (28)              (10,001)
Change in trade and other payables                                                                                 (1,665)                  1,100                  (182)                       68
Share options charges                                                                                                             632                     369                     632                     369

Cash flows from operating activities                                                                                 12,546                14,417                    (23)                       (2)

28. Capital commitments

Neither the Group nor Company had any capital commitments at 31 December 2013 or at 31 December 2012.

29. Contingent liabilities

Neither the Group nor Company had any contingent liabilities at 31 December 2013 or at 31 December 2012.

30. Pensions

The Group operates a defined contribution group personal pension scheme for the benefit of certain Directors and employees.

                                                                                                                                                                                           31 December    31 December
                                                                                                                                                                                                           2013                   2012
The Group                                                                                                                                                                                   £000s                 £000s

Contributions payable by the group for the year                                                                                                                         307                     306

The Group also operates a stakeholder pension plan available to all employees.

31. Leasing commitments
The future aggregate minimum lease payments under non-cancellable operating leases are as follows:

                                                                                                                                                             31 December    31 December          1 January 
                                                                                                                                                                            2013                   2012                   2012
                                                                                                                                                                    Land and           Land and           Land and
                                                                                                                                                                    buildings           buildings           buildings
                                                                                                                                                                         £000s                 £000s                 £000s

No later than one year                                                                                                                                        287                     361                     286
Later than one year and no later than five years                                                                                             589                     753                     900
Later than five years                                                                                                                                           220                     317                     415

                                                                                                                                                                          1,096                  1,431                  1,601

32. Related party transactions

The group paid £163,000 (year ended 31 December 2012: £642,000) for services from Fasken Martineau LLP and £15,000 for services from
Pinsent Mason (year ended 31 December 2012: £nil), both firms had Paul Ranson as a partner during 2013. At 31 December 2013 there
was a balance of £33,238 (31 December 2012: £13,624) outstanding in respect of services from Fasken Martineau LLP and £nil in respect
of Pinsent Mason.

Alliance Pharma plc | Annual Report 2013

59

Notes to the Financial 
Statements continued
for year ended 31 December 2013

32. Related party transactions continued

Financial Statements

Lynette Booley, wife of director Tony Booley, was paid £nil (31 December 2012: £14,000) for promotional services and goods. £nil was
outstanding at 31 December 2013 (year ended 31 December 2012: £nil).

The group paid £nil (year ended 31 December 2012: £24,000) for services from Patient Connect Service Limited, a company of which
Thomas Casdagli is a director. 

During the year the Company received funds of £12,450,000 (year ended 31 December 2012: £219,000) from its subsidiary Alliance
Pharmaceuticals Limited. Net payments of £485,000 (year ended 31 December 2012: £2,359,000) were made by Alliance Pharmaceuticals
Limited on behalf of Alliance Pharma plc. Interest of £1,464,000 (year ended 31 December 2012: £1,309,000) was charged to Alliance
Pharmaceuticals Limited on the total outstanding debt. During the year the Company re-invested £5,550,000 (year ended 31 December
2012: £2,010,000) in Alliance Pharmaceuticals Limited. During the year an amount of £632,000 (year end 31 December 2012: £369,000)
was charged to Alliance Pharmaceuticals Limited by the Company for the employee share based payment. The amount owed by Alliance
Pharmaceuticals Limited at the year-end is £42,108,000 (31 December 2012: £43,161,000).

Dividends declared by Alliance Pharmaceuticals Limited due to the Company are £nil for the year ended 31 December 2013 (for the year
ended 31 December 2012: £10,000,000, for the year ended 31 December 2011: £2,000,000). During the year dividends of £10m were paid
by Alliance Pharmaceuticals Limited to the Company.

During the year the Group made payments on behalf of Unigreg of £299,000 (year ended 31 December 2012: £377,000). Interest receivable
from Unigreg was £52,000 (year ended 31 December 2012: £48,000).

33. Joint Venture

Name

Principal Activity                                                                       Country of Incorporation                                     % Owned

Unigreg Ltd

Distribution of pharmaceutical products to China                      British Virgin Islands                                                 60

The Group considered the existence of substantive participating rights held by the minority shareholder which provide that shareholder
with a veto right over the significant financial and operating policies of Unigreg Ltd and determined that, as a result of these rights, the
Group does not have control over the financial and operating policies of Unigreg Ltd, despite the Group’s 60% ownership interest. 

The company is accounted for using the proportionate consolidation method of accounting. The following amounts are included in the
balance sheet and the income statement of the Group, being the Group’s share of those items.

Inter-company transactions are also eliminated proportionally.

                                                                                                                                                            31 December    31 December          1 January
                                                                                                                                                                            2013                   2012                   2012
                                                                                                                                                                         £000s                 £000s                 £000s

Intangible fixed assets                                                                                                                                     1,950                  1,950                  1,950
Current assets                                                                                                                                                     200                     658                     853
Current liabilities                                                                                                                                                (54)                   (145)                   (309)

Net assets                                                                                                                                                         2,096                  2,463                  2,494

                                                                                                                                                                Year ended        Year ended        Year ended
                                                                                                                                                             31 December    31 December    31 December
                                                                                                                                                                             2013                   2012                   2011
                                                                                                                                                                         £000s                 £000s                 £000s

Income                                                                                                                                                                  239                  2,475                  1,812
Cost of sales                                                                                                                                                      (129)                (1,415)                (1,029)
Administration and marketing expense                                                                                                         (111)                   (239)                   (249)

(Loss)/profit on ordinary activities before taxation                                                                                            (1)                     821                     534

34. Ultimate controlling party

There is no single ultimate controlling party.

35. Subsequent event

On 14 January 2014, the Company acquired the rights to the thyroid product Irenat from subsidiaries of Bayer AG ("Bayer") for a
consideration of €3.3 million. Irenat, a sodium perchlorate monohydrate, is marketed in Germany and is mainly used for diagnosing and
treating hyperthyroidism. In the 12 months to October 2013, total sales of Irenat by Bayer were €0.8 million and the gross margin
generated was €0.5 million.

60 Alliance Pharma plc | Annual Report 2013

Shareholder Information

Supplementary Information

Shareholder enquiries

The Company’s share register is maintained on our behalf by Capita Asset Services, who are responsible for updating the register,
including details of changes to shareholders’ addresses and purchases and sales of the Company’s shares. If you have any questions
about your shareholding in the Company or need to notify any changes to your personal details you should write to Capita Asset Services,
PXS1, 34 Beckenham Road, Beckenham, Kent BR3 4ZF or telephone 0871 664 0300 (calls cost 10p per minute plus network extras, lines
are open 9:00am to 5:30pm Monday to Friday). 

Financial Calendar

Annual General Meeting

Final dividend record date

Payment of final dividend

21 May 2014

13 June 2014

10 July 2014

Interim results announcement

10 September 2014

Year end

31 December 2014

Preliminary announcement

March 2015

Shareholder Analysis

Below is an analysis of the share register by size of holding as at 6 January 2014:

                                                                                                                                                              Proportion of         Number of     Proportion of
Size of shareholding                                                                                                                          shareholders       shares held               shares

1-5,000                                                                                                                                                                 22%              395,695                 0.16%
5,001-10,000                                                                                                                                                        13%              858,792                 0.34%
10,001-50,000                                                                                                                                                      39%           8,049,629                 3.24%
50,001-100,000                                                                                                                                                    12%           7,050,331                 2.83%
100,001-500,000                                                                                                                                                    7%         11,878,494                 4.78%
500,001-1,000,000                                                                                                                                                 3%         18,637,596                 7.50%
1,000,001-5,000,000                                                                                                                                             2%         56,764,970               22.84%
5,000,001-10,000,000                                                                                                                                           1%         19,336,071                 7.78%
10,000,001-50,000,000                                                                                                                                         1%       125,597,976               50.53%

                                                                                                                                                                           100%       248,569,554                  100%

As at 6 January 2014 the Company has 353 registered shareholders.

Alliance Pharma plc | Annual Report 2013

61

Five Year Summary

                                                                                                           Year ended        Year ended        Year ended        Year ended       Year ended
                                                                                                      31 December    31 December    31 December    31 December    31 December
                                                                                                                      2009                   2010                   2011                   2012                   2013 
                                                                                                                         £m                      £m                      £m                      £m                     £m

Revenue                                                                                                         31.2                    49.9                    46.0                    44.9                    45.5
Operating profit before exceptional items                                                  11.2                    18.7                    12.3                    12.3                    13.4
Exceptional operating items                                                                        (2.8)                    (1.7)                         -                         -                         -
Operating profit after exceptional items                                                       8.4                    17.0                    12.3                    12.3                    13.4
Exceptional finance items                                                                                 -                    (1.8)                         -                         -                         -
Profit before tax before exceptional items                                                   8.5                    16.4                    10.7                    10.8                    12.0

Profit/(loss) before tax after exceptional items                                            5.7                    12.9                    10.7                    10.8                    12.0
Intangible assets                                                                                           44.9                    60.3                    66.1                    79.9                    89.1
Tangible assets                                                                                               0.1                      0.9                      0.8                      0.6                      0.6
Current assets                                                                                              11.7                    16.2                    15.4                    20.2                    16.9
Current liabilities                                                                                          11.4                    17.0                    13.9                    22.0                    14.9
Equity                                                                                                             16.6                    36.1                    44.1                    51.8                    64.7

Average shares in issue (millions)                                                            173.2                  226.1                  238.6                  240.9                 250.8
Shares in issue at period end (millions)                                                   193.3                  236.1                  240.1                  243.0                 264.1

Earnings per share – basic (p)                                                                    2.37                    3.96                    3.62                    3.61                    3.82
Earnings per share – adjusted basic (p)                                                     3.55                    5.07                    3.62                    3.61                    3.82

62 Alliance Pharma plc | Annual Report 2013

Advisors

Supplementary Information

AUDITOR

FINANCIAL PR

Grant Thornton UK LLP

Buchanan Communications

Hartwell House

55-61 Victoria Street

Bristol

BS1 6FT

BANKERS

107 Cheapside

London

EC2V 6DN

REGISTRARS

Capita Asset Services

Lloyds Bank Corporate Markets

PXS 1

The Atrium

Davidson House

Forbury Square

Reading

Berkshire

RG1 3EU

Royal Bank of Scotland

3rd Floor

3 Temple Back East

Bristol

BS1 6DZ

34 Beckenham Road

Beckenham

Kent

BR3 4ZF

REGISTERED OFFICE

Avonbridge House

Bath Road

Chippenham

Wiltshire

SN15 2BB

COMPANY NUMBER

CORPORATE ADVISORS

04241478

Numis Securities Ltd

10 Paternoster Square

London

EC4M 7LT

Alliance Pharma plc | Annual Report 2013

63

Supplementary Information

Cautionary statement regarding forward-looking statements

This Annual Report has been prepared for the members of the Company and no one else. The Company, its Directors, employees or
agents do not accept or assume responsibility to any other person in connection with this document and any such responsibility or
liability is expressly disclaimed.

This Annual Report contains certain forward-looking statements with respect to the principal risks and uncertainties facing Alliance. By
their nature, these statements and forecasts involve risk and uncertainty because they relate to events and depend on circumstances that
may or may not occur in the future. There are a number of factors that could cause actual results or developments to differ materially
from those expressed or implied by these forward-looking statements and forecasts. The forward-looking statements reflect the
knowledge and information available at the date of preparation of this Annual Report, and will not be updated during the year. Nothing in
this Annual Report should be construed as a profit forecast.

The Report of the Directors in this Annual Report has been drawn up and presented in accordance with English company law and the
liabilities of the Directors in connection with that report shall be subject to the limitations and restrictions provided by such law. 

In particular, Directors would be liable to the Company (but not to any third party) if the Report of the Directors contains errors as a result
of recklessness or knowing misstatement or dishonest concealment of a material fact, but would not otherwise be liable.

TRADEMARKS

The following are registered trademarks of Alliance Pharmaceuticals Limited (a subsidiary of Alliance Pharma plc) and are protected in a
number of countries: 

AbsorbagelTM, AcnisalTM, ALLIANCE, ALLIANCE and Logo, ALLIANCE GENERICS, ALLIANCE PHARMACEUTICALS, AlphadermTM,
AnbesolTM, AquadrateTM, Ashton & Parsons Infants’ PowderTM, AtaraxTM, AvloclorTM, BuccastemTM, CeanelTM, ClearWayTM, ClearWay MiniTM,
ClearWay Stoma BridgeTM, DeoGelTM, DeltacortrilTM, Dermamist, DistamineTM, ForcevalTM, HydromolTM, Irenat™, IsprelorTM, LiftTM, Lift+TM,
Lift PlusTM, Lypsyl™, Lypsyl – It’s On Everyone’s Lips™, Lypsyl Kissables™, Lypsyl Shimmer™, LysovirTM, MetedTM, MolluDabTM, NaseptinTM,
NaturCareTM, NaturCare BreezeTM, NaturCare FragantTM, NaturCare ZestTM, NaturCare IPDTM, Nu-SealsTM, OcclusalTM, OndemetTM, 
OPUS and Logo, PaludrineTM, PavacolTM, Pavacol-DTM, PentraxTM, PeriostatTM, PermitabsTM, PosidormTM, QuinodermTM and Quinoderm Q
device, RizudermTM, Roman in a chariot device, SavarineTM, SkinSafeTM, SkinSafe Non Sting Protective FilmTM, Syntometrine™, 
Terra-cortrilTM, ThwartTM, TimodineTM, UnifluTM, UnigregTM.

The following are all used under licence by Alliance Pharmaceuticals Limited:

XenazineTM is a registered trademark of Biovail Laboratories International (Barbados). 

GelclairTM is a registered trademark of Helsinn Healthcare S.A. 

ImmuCystTM is a registered trademark of Sanofi Pasteur Limited. 

64 Alliance Pharma plc | Annual Report 2013

Designed & produced by Design Wall.

Alliance Pharma plc
Avonbridge House
Bath Road
Chippenham
Wiltshire
SN15 2BB
United Kingdom

T:  +44 (0)1249 466966
F:  +44 (0)1249 466977
E:  ir@alliancepharma.co.uk

www.alliancepharma.co.uk