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Alliance Pharma

aph · LSE Technology
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Employees 201-500
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FY2022 Annual Report · Alliance Pharma
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WE ARE

ALLIANCE

Alliance Pharma plc  
Annual Report and Accounts  
2022

Strategic Report

Governance

Financial Statements

Additional Information

Company Overview
Who We Are 

2022 Performance Overview 

2022 A Year in Review 

Purpose, Vision, Strategy, Values 

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C O N T E N T S

AN ALLIANCE OF 
PEOPLE, PARTNERS 
AND BRANDS, 
WORKING 
TOGETHER TO 
ACHIEVE MORE

How we report to our stakeholders

For more information visit  
alliancepharmaceuticals.com

Annual Report

Online Sustainability Report

Our website

View our report online at 
alliancepharmaceuticals.
com/investors/2022-annual-
report/

Online sustainability 
report at osr22.
alliancepharmaceuticals.com

Visit our main site for 
further information at 
alliancepharmaceuticals.com

Company Overview
Who We Are 
2022 Performance Overview 
2022 A Year in Review 
Purpose, Vision, Strategy, Values 

Strategic Report
 Chief Executive’s Review 
Market Overview 
 Our Strategy 
Spotlight on… 

Marketing excellence 
Innovation and development 
ScarAway™ and Kelo-Cote™  
US acquisition 
Culture, people and values 

Key Performance Indicators 
Sustainability 
Spotlight on… 

Managing our packaging estate 
Developing our response to  
climate change 

TCFD 
Stakeholder Engagement 
Financial Review 
 Principal Risks and Uncertainties 

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Governance
 Chair’s Introduction 
Our Governance Structure 
Board of Directors 
Governance 
Nomination Committee Report 
Audit and Risk Committee Report 
Remuneration Committee Report 
ESG Committee Report 
Directors’ Report 

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102

Financial Statements
Independent Auditor’s Report 
Consolidated Income Statement 
Consolidated Statement of  
Comprehensive Income 
Consolidated Balance Sheet 
Company Balance Sheet 
Consolidated Statement of Changes  
in Equity 
106
Company Statement of Changes in Equity  107
Consolidated and Company Cash  
Flow Statements 
Notes to the Financial Statements 

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105

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109

Additional Information
Unaudited Information 
Five Year Summary 
 Advisers and Key Service Providers 
 Cautionary Statement 
Glossary 

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Alliance Pharma plcAnnual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Strategic Report
Strategic Report

Governance
Governance

Financial Statements
Financial Statements

Additional Information
Additional Information

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W H O   W E   A R E

Company Overview
Company Overview
Who We Are 
Who We Are 

2022 Performance Overview 
2022 Performance Overview 

2022 A Year in Review 
2022 A Year in Review 

Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 

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WE ARE ALLIANCE

An international consumer healthcare company, 
empowering people to make a positive difference to their health and wellbeing, 
through making our trusted and proven brands available around the world. 

A TEAM OF

TALENTED PEOPLE285

as at 31 December 2022

BASED IN

STRATEGIC LOCATIONS8

Working together to deliver value for our stakeholders through maximising the value of our brands.

INVESTING IN OUR 
PRIORITY BRANDS 
AND CHANNELS

INNOVATING 
TO ENSURE OUR 
BRANDS REMAIN 
RELEVANT

SELECTIVELY 
EXTENDING THE 
GEOGRAPHIC REACH 
OF OUR BRANDS

For more information visit  
For more information visit  
alliancepharmaceuticals.com
alliancepharmaceuticals.com

Outsourcing capital-intensive activities, such as manufacturing and logistics, to allow us to focus on what we do best.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report
Strategic Report
Strategic Report
Strategic Report

Governance
Governance
Governance
Governance

Financial Statements
Financial Statements
Financial Statements
Financial Statements

Additional Information
Additional Information
Additional Information
Additional Information

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02
02
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2 0 2 2   P E R F O R M A N C E   O V E R V I E W

Company Overview
Company Overview
Company Overview
Who We Are 
Who We Are 
Who We Are 

2022 Performance Overview 
2022 Performance Overview 
2022 Performance Overview 

2022 A Year in Review 
2022 A Year in Review 
2022 A Year in Review 

Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 

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SEE-THROUGH REVENUE*

UNDERLYING PROFIT BEFORE TAX*

UNDERLYING BASIC EPS*

£172.0m +1%

£30.3m -28%

(2021: £169.6m)

(2021: £42.2m)

4.28p -33%

(2021: 6.39p)

STATUTORY REVENUE

REPORTED PROFIT BEFORE TAX

REPORTED BASIC EPS

£167.4m +3%

£5.2m -71%

(2021: £163.2m)

(2021: £18.2m)

0.17p -88%

(2021: 1.37p)

FREE CASH FLOW*

NET DEBT*

£15.8m -48%

£102.0m +17%

(2021: £30.2m)

(2021: £87.0m)

For more information visit  
For more information visit  
For more information visit  
alliancepharmaceuticals.com
alliancepharmaceuticals.com
alliancepharmaceuticals.com

* Non-IFRS Alternative Performance Measures (‘APMs’), (see note 31).
See-through revenue includes all sales from Nizoral™ as if they had been invoiced by Alliance as principal. For statutory accounting purposes the product margin relating to Nizoral™ sales made on an agency basis is included within Revenue, in line with IFRS 15.

Alliance Pharma plc Annual Report and Accounts 2022

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Strategic Report
Strategic Report
Strategic Report
Strategic Report

Governance
Governance
Governance
Governance

Financial Statements
Financial Statements
Financial Statements
Financial Statements

Additional Information
Additional Information
Additional Information
Additional Information

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03
03
03

Company Overview
Company Overview
Company Overview
Company Overview
Who We Are 
Who We Are 
Who We Are 
Who We Are 

2022 Performance Overview 
2022 Performance Overview 
2022 Performance Overview 
2022 Performance Overview 

2022 A Year in Review 
2022 A Year in Review 
2022 A Year in Review 
2022 A Year in Review 

Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 

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2 0 2 2   A   Y E A R   I N   R E V I E W

Whilst trading performance in 2022 was not as strong 
as had been anticipated at the start of the Year, Alliance 
successfully completed a highly strategic acquisition of 
ScarAway™ and the rights to Kelo-Cote™ in the US in 
March and delivered the first new product launch from 
its innovation and development platform. The Group has 
robust plans in place to support a return to growth in 2023.

 ›

Prescription Medicines performance stable, with revenues of 
£46.8m (2021: £47.8m), down 2% CER2.

 ›

 › Underlying PBT declined 28% largely due to less favourable 
product mix with a lower proportion of Kelo-Cote™ and 
Amberen™ sales. Reported PBT declined 71% due to higher 
non-cash impairment charges of £18.2m, including £12.0m 
for Amberen.
Free cash flow was lower by 48% at £15.8m, primarily 
reflecting the timing of sales and cash receipts. Cash from 
operations declined by 45% to £24.9m.
Following the highly strategic US acquisition for $19.4m 
(£14.8m), net debt increased to £102.0m moving Group 
leverage to 2.57 times at 31 December 2022 (1.73 times at 
31 December 2021).

 ›

 › Consumer Healthcare see-through revenue1 up 3% to 
£125.2m (2021: £121.8m) (down 3% CER2) with 16% 
growth in Other Consumer brands partially offsetting softer 
performance in key brands.
Revenue growth impacted by lockdown in China, associated 
temporary business-to-business (‘B2B’) disruption to the 
supply chain, slower recovery in B2B demand for  
Kelo-Cote™ and a one-off destocking effect, but boosted  
by the US acquisition and FX gains.

 ›

 ›

 ›

Integration of the US acquisition completed in just four 
months, successfully leveraging our established infrastructure, 
with revenues in line with expectations.
Last remaining NizoralTM marketing authorisations 
transferred from Johnson & Johnson (‘J&J’) to Alliance in 
both China and Vietnam; new top-tier Chinese distributor 
appointed and manufacturing supply consolidation 
progressing well, which will result in improvements in cost 
efficiencies in the near future.

1  Non-IFRS Alternative Performance Measure (‘APM’), (see note 31).

  See-through revenue includes all sales from Nizoral™ as if they had been invoiced by 
Alliance as principal. For statutory accounting purposes the product margin relating to 
Nizoral™ sales made on an agency basis is included within Revenue, in line with IFRS 15.

2  Constant exchange rates.

For more information visit  
For more information visit  
For more information visit  
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alliancepharmaceuticals.com
alliancepharmaceuticals.com
alliancepharmaceuticals.com
alliancepharmaceuticals.com

 ›

 ›

 ›

 ›

 ›

  See our Spotlight on ScarAway™ and Kelo-CoteTM US acquisition 
on page 22

  See the Chief Executive’s Review on page 06 

First new product launched from our innovation and 
development programme – Kelo-Cote™ Kids. 

  See our Spotlight on innovation and development on page 20 

Scope 1 and 2 emissions target set to achieve net zero in 
2030, with an interim reduction of 65% by 2025. 

  See our Spotlight on developing our response to climate 
change on page 33 

Re-certified as a Great Place To Work® (GPTW) in the UK, 
China and Singapore with new certifications in the US and 
France and a Trust Index© rating of 79% (2021: 76%). 

  See our Spotlight on culture, people & values on page 24 

 › Updated and refined our Purpose, Vision and Strategy to 
better align with the evolving dynamics of the consumer 
healthcare market. 

  See Our Strategy on page 12 

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Strategic Report
Strategic Report
Strategic Report
Strategic Report
Strategic Report

Governance
Governance
Governance
Governance
Governance

Financial Statements
Financial Statements
Financial Statements
Financial Statements
Financial Statements

Additional Information
Additional Information
Additional Information
Additional Information
Additional Information

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P U R P O S E ,   V I S I O N ,   S T R A T E G Y ,   V A L U E S

A clear purpose

We empower people 
to make a positive 
difference to their health 
and wellbeing
Our refreshed purpose, and  
the refined vision that it 
supports, enable us to align 
ourselves more closely to 
changing market dynamics.
Our strategy focuses on those 
categories in which we can 
add most value, to promote 
the successful evolution of our 
business and meet specific 
consumer needs.
Our strong culture will enable  
us to implement the 
transformation needed to deliver 
our strategic priorities.
Our values remain unchanged.

  See our purpose and vision on page 11

s
e
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f
e

D

Company Overview
Company Overview
Company Overview
Company Overview
Company Overview
Who We Are 
Who We Are 
Who We Are 
Who We Are 
Who We Are 

2022 Performance Overview 
2022 Performance Overview 
2022 Performance Overview 
2022 Performance Overview 
2022 Performance Overview 

2022 A Year in Review 
2022 A Year in Review 
2022 A Year in Review 
2022 A Year in Review 
2022 A Year in Review 

Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 
Purpose, Vision, Strategy, Values 

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For more information visit  
For more information visit  
For more information visit  
For more information visit  
For more information visit  
alliancepharmaceuticals.com
alliancepharmaceuticals.com
alliancepharmaceuticals.com
alliancepharmaceuticals.com
alliancepharmaceuticals.com

Guides

Delivers

Our Vision

Our Purpose

Our Strategy

See page 11

See page 11

See page 12

E

n
a
b
l
e
s

Our Values

Our Culture

Our Business Model 

See our website

See page 24

See our website

Shape

Supports

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plcAnnual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company OverviewAlliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

05

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plc Annual Report and Accounts 2022

Strategic Report

“ As we continue on our growth 

trajectory journey, our portfolio 
continues to provide a robust platform 
from which to grow our consumer 
healthcare brands.”

Peter Butterfield, Chief Executive Officer

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

06

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

 C H I E F   E X E C U T I V E ’ S   R E V I E W

TRADING PERFORMANCE
Overview
We recognise that 2022 didn’t deliver the trading performance 
that we expected at the start of the year. This was largely due 
to underperformance in two discrete areas of our business, 
Kelo-Cote™ in the China business-to-business (‘B2B’) channel, 
and Amberen™ in the bricks and mortar channel, and was 
set against a challenging economic backdrop with the war in 
Ukraine and COVID 19-related lockdowns in China creating 
supply disruption. 

However, we were able to successfully leverage our existing 
infrastructure, by acquiring ScarAway™ and the US rights 
to Kelo-Cote™ in March 2022, to create our first truly 
global brand, bringing additional growth opportunities into 
the business. We also started to realise the benefits of our 
investment in innovation and development with the launch of 
Kelo-Cote™ Kids. 

We start 2023 in a good position, having refreshed our 
strategy, to better align our business with the evolving dynamics 
of the Consumer Healthcare market. Going forward, our efforts 
will be focused on those market segments in which we already 
have a strong presence and expertise in order to drive solid 
organic revenue growth above that of the broader Consumer 
Healthcare market. 

A challenging year
The implementation of rigid lockdowns in China from March 
prevented the movement of Kelo-Cote™ across the border from 
Hong Kong, effectively closing the cross-border e-commerce 
(‘CBEC’) channel and leading to declines in the CBEC scar 
treatment market in H1. During this period, consumer demand 
remained strong and the domestic online market grew, with 
Kelo-Cote™ gaining share.

SEE-THROUGH REVENUE

£172.0m
+1% (2021: £169.6m) 

See our operational  
performance on  
page 43

Whilst the CBEC market returned to growth in H2, and 
Kelo-Cote™ delivered a strong performance in the business-
to-consumer (‘B2C’) channel, winning a prestigious Tmall 
global award for surpassing RMB100m (c. £12m) in sales, the 
B2B market was slower to recover, with traders reluctant to 
restock Kelo-Cote™ for fear that counterfeit product would be 
available at a lower price. This problem was compounded by a 
one-off destocking decision by our CBEC distributor. 

We continue to work with our CBEC distributor to further develop 
this channel, expand reach and optimise sales. Our B2C channel 
is well developed, and we have refined our strategy to increase 
our presence in the significant B2B channel, which incorporates 
additional distributor support. In light of that, we anticipate that 
sales will build steadily through 2023.

Amberen™ sales performance was impacted by declines in 
the underlying bricks and mortar market due to an increase in 
prevalence of cheaper, white-label alternatives and switching to 
online platforms, in addition to the loss of a leading discount store 
account. Alliance is committed to increasing the performance 
of Amberen™ in the higher growth e-commerce channel whilst 
optimising sales in bricks and mortar where appropriate. 

The brand's packaging has been re-launched featuring stronger 
claims, and advertising investment continues focused on digital, 
video, social media and search engine optimisation to drive 
share gains.

We were disappointed by the CMA’s finding that four 
companies, including Alliance, infringed competition law in 
relation to the sale of prescription prochlorperazine between 
June 2013 and July 2018. We fundamentally disagree with the 
findings, and the proposed fine, and look forward to presenting 
our case at the Competition Appeal Tribunal, which is scheduled 
to commence on 5 June 2023.

Strengthening our Consumer Healthcare business
We acquired ScarAway™ and the US rights to Kelo-Cote™ in 
March 2022 to create the Group’s first fully global brand. The 
integration of both assets went very smoothly, with full transition 
completed in just four months and post-acquisition sales in 
line with expectations. This successful integration was made 
possible by the implementation of our ERP system in 2021, 
and we have used the learnings from this project to create a 
blueprint for future acquisitions.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

07

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

 C H I E F   E X E C U T I V E ’ S   R E V I E W   C O N T I N U E D

2022 was also the year in which we finally gained full control of 
the remaining marketing authorisations for Nizoral™ across the 
APAC region, securing China in March 2022 and Vietnam in 
May 2022, following the acquisition of the Nizoral™ brand from 
Johnson & Johnson (‘J&J’) in 2018. The transfer of the marketing 
authorisation in China allowed us to transition to a new top-tier 
local distributor at the end of H1 2022 to service the brand’s 
largest market. Our new distributor offers a larger sales team than 
the partner we inherited from J&J and has fewer products in its 
portfolio, which ensures more sales resources are dedicated to  
our account.

Progressing our innovation and  
development programme
Our dedicated Innovation and Development (‘I&D’) team 
was established in 2021 to support the organic growth in our 
Consumer Healthcare brands and in April 2022 we launched 
the first product from this initiative, Kelo-Cote™ Kids, into the 
CBEC channel. With only two other products in the children’s 
CBEC scar treatment market in China we were able to drive 
market share gains to 39% in December 2022, delivering 
incremental growth in the brand.

For more information visit  
alliancepharmaceuticals.com

The performance of this launch has exceeded our initial 
expectations; new product innovation approvals have been 
submitted to allow us to launch Kelo-Cote™ Kids in the UK and 
Germany in 2023. 

 See our Spotlight on innovation and development on page 20

We have a number of new products, line extensions and 
reformulations in our I&D pipeline and have since launched 
Canker-X, part of the Aloclair™ brand franchise, in the US in 
January 2023. With investment of £1m – £2m per annum in I&D 
we aim to achieve 10% of Consumer Healthcare sales through 
products developed on our I&D platform in the next five years.

We gained greater understanding of the constituents of our 
packaging estate, both primary and secondary, and the steps we 
need to take to promote recycling and reduce the use of single-
use plastics. Our newly appointed sustainable sourcing lead is 
helping us to progress these initiatives in 2023 with a number of 
pilot projects planned. 

  See our Spotlight on managing our packaging estate on page 31

Building a strong alliance of colleagues
Our business, and the delivery of our strategy, is only possible 
due to our network of talented, dedicated colleagues. We 
currently employ more than 285 people in eight locations around 
the world. We created 18 new roles in 2022, across all our 
geographies, as we looked to meet our evolving business needs, 
increasing our capabilities in data analysis, sustainable sourcing 
and packaging, ERP and sales and marketing in the US.

Refining our Purpose, Vision and Strategy 
Throughout 2022 we have worked to refine our Purpose and 
Vision to align with our transformation to a predominantly 
Consumer Healthcare company. We have also worked to evolve 
our strategy to better position the Company for the years ahead 
and in response to changing underlying market dynamics. Going 
forward, our aim is to drive solid organic revenue growth above 
that of the broader consumer healthcare market.

This updated strategy provides a more targeted approach, 
identifying the key global categories in which we will operate, 
and more clearly defines the areas in which we would consider 
future acquisitions. Going forward, we will focus our resources 
on the global priority categories of helping damaged skin and 
supporting healthy ageing. 

 See our Strategy on page 12

Continuing our sustainability journey
We made good progress against our environmental 
sustainability agenda in 2022, setting a target to reach net 
zero for all Scope 1 & 2 emissions by 2030. This year we also 
undertook an initial risk assessment and scenario analysis to 
support the publication of our first voluntary stand-alone TCFD 
report and more extensive voluntary TCFD disclosures on our 
journey to full TCFD compliance.

  See our Spotlight on developing our response to climate change  
on page 33

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

08

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

 C H I E F   E X E C U T I V E ’ S   R E V I E W   C O N T I N U E D

We have also expanded our talent development programmes 
to ensure we attract and retain an appropriate mix of skilled 
professionals. In 2022 we launched our graduate and year 
in industry programmes to support those at the early stages 
of their career development and to complement our existing 
apprenticeship programme in the UK.

As COVID-19 restrictions eased around the world we were finally 
able to bring together colleagues from all our offices, with the 
exception of Shanghai, for our first global employee conference. 
The conference provided an opportunity for colleagues to 
network, share ideas and discuss our updated purpose, vision and 
strategy. Due to continued COVID-19 lockdowns, we organised 
a parallel event to allow our team in Shanghai to participate and 
share the experience. 

Our investment in colleague engagement continues to pay 
dividends as evidenced by our re-certification as a Great Place 
to Work in the UK, China and Singapore. We were delighted to 
receive certification for the first time in the US and France meaning 
that all our qualifying offices are now certified. In the 2022 survey 
we were pleased to have received an overall Trust Index rating of 
79% (2021: 76%) with 82% of participants globally saying that 
Alliance was a Great Place to Work (2021: 81%).

 See our Spotlight on culture, people and values on page 24

On behalf of the Board, I would like to thank all those colleagues 
who helped us to deliver our achievements in 2022.

Board and executive changes

In February 2023 we welcomed Jeyan Heper to Alliance, in the 
newly created position of Chief Operating Officer. Jeyan has 
a strong track record of strategic leadership in the international 
consumer health market, overseeing a number of global 
programmes and driving growth in flagship brands. 

Outlook for 2023
Our clear focus on the core Consumer Healthcare business in 
addition to our well-established, scalable platform across EMEA, 
APAC and the US, should support good organic growth in the near 
term. Whilst 2022 presented some challenges to the business, we 
have robust plans in place to drive growth in 2023 and the Board’s 
expectations for full year performance are unchanged.

As indicated in the January trading update, Kelo-Cote™ revenues 
are expected to build through the year, supported by strong end-
consumer demand. The China cross-border e-commerce market 
for Kelo-Cote™ has shown early signs of recovery with in-market 
demand and sales orders increasing over the first two months of 
the year, and we expect total revenue growth for the entire Kelo-
Cote™ franchise to be above 20% in 2023. We expect to see 
high single-digit revenue growth from Nizoral™ in 2023, as we 
accelerate the roll-out of our tested strategic plan for the brand in 
partnership with our new distributors in China and Vietnam. 

Amberen™ faced some temporary headwinds in early 2023 due 
to supply challenges at Amazon which are being addressed. The 
underlying market conditions are positive and this, together with 
our revised marketing plans, mean that we still anticipate double-
digit revenue growth for Amberen on a like-for-like basis.

Our portfolio of other consumer brands is expected to deliver 
high single-digit revenue growth, substantially ahead of the 
broader consumer healthcare market.

In his career spanning more than 25 years Jeyan has held senior 
executive roles at Procter & Gamble, Danone Group and Ansell’s 
sexual wellness global business, before it was spun-out to 
become Lifestyles Healthcare, a private equity/pharma-owned 
company where Jeyan became CEO.

Jeyan will help to bolster the Group’s operational capabilities, 
identify growth opportunities, and help drive the Company’s 
strategy to expand its consumer health presence through 
leveraging his experience of e-commerce in China and the US, 
and improving operational effectiveness.

Jeyan joined the Alliance Board, which was strengthened further 
by the appointment of Martin Sutherland as an additional 
Independent Non-Executive Director (‘NED’). Martin is a senior 
executive with over 30 years’ experience in global businesses 
and is currently a NED at Forterra plc and Reliance Cyber Ltd. 
Prior to this, Martin was CEO of De La Rue PLC. Martin has a 
proven track record of delivering growth through new product 
innovation, market diversification and international expansion.

Martin’s experience will bring a new perspective to complement 
the strong consumer healthcare knowledge already present on 
the Board.

Peter Butterfield
Chief Executive Officer
20 March 2023

 See our Board of Directors on pages 61 and 62

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Innovation and development 

ScarAway™ and Kelo-Cote™  
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Key Performance Indicators 

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Spotlight on…

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31

Developing our response to  
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TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

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35

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42

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For more information visit  
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M A R K E T   O V E R V I E W

The macro factors shaping our business

1. Ageing global population
By 2030, c.1.4 billion people globally will be 
over 60 years old, with an associated increase 
in demand for healthcare. Education and 
income advancement in emerging markets will 
also contribute to this trend.

2. Growth in self-care
There is a growing trend towards more 
proactive management of health and 
wellbeing, rather than an individual just 
taking action when they feel unwell. The rising 
cost of providing public healthcare means 
governments are becoming more supportive 
of this, increasing the availability of OTC 
medicines and supporting pharmacists and 
nutritionists to provide more first line care  
and support.

3. Digital health
The increasing adoption of digital health 
solutions is providing consumers, health 
practitioners and manufacturers with greater 
access to information on medical conditions, 
treatments, and outcomes. Regular feedback 
from a digital device can lead to a more 
engaged consumer who is willing to take 
more actions to manage their health. By 
aggregating that feedback across many 
consumers, we can identify emerging needs 
or gaps in the market and develop new 
products and services to meet them. 

2

3

1

Growth in 
self-care

Ageing global 
population

Six
macro factors 
impacting our 
business

Economic 
uncertainty

Digital 
health

Environmental 
sustainability

Omni-channel 
retail

4

4. Omni-channel retail
Whilst there has been a rise in the purchase 
of health products and services online, this 
is not the only way that consumers want to 
transact. A purchasing journey may include 
multiple or omni-channels, such as first 
seeking advice in a pharmacy but ultimately 
purchasing from a website via a mobile 
phone. Each channel must be optimised so 
that the consumer is able to find what they 
want and complete their purchase easily. 

5. Environmental sustainability
With greater focus and scrutiny on 
sustainability, the way a business operates 
matters more than ever. Many consumers 
now actively seek companies and brands 
whose values align with their own, for example 
choosing products containing sustainably 
sourced ingredients or with environmentally 
friendly packaging.

6. Economic uncertainty
Businesses operate in a volatile, uncertain, 
complex, and ambiguous world where 
being agile, resilient and managing cost is 
essential to success. Faced with a higher cost 
of living, consumers tend to look for brands 
and services that offer the best value to them, 
and with proven results, rather than risk using 
something unknown.

6

5

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M A R K E T   O V E R V I E W   C O N T I N U E D

Former paradigm
A Reactive Patient

People only took action when they felt unwell.

Good health

Poor health

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31

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New paradigm
A Proactive Consumer

Innovations and new technologies allow a more proactive management 
of health.

Eating healthily

Connected health 
(wearables, 
mHealth, 
telehealth, etc.)

Practising 
sport

Asking 
questions 
about 
health

Finding 
medicine/ 
self-medication

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M A R K E T   O V E R V I E W   C O N T I N U E D

We have considered these macro factors, in combination with our key areas of 
expertise, in order to refresh our purpose and refine our vision, which we believe 
places us in a stronger position to continue the successful evolution of our business.

Purpose
We empower people to make  
a positive difference to their  
health and wellbeing

Vision
To be a high performing consumer  
healthcare company, built on a portfolio  
of leading, trusted and proven brands

We use the word ‘empower’ in recognition of the shift that we are witnessing from 
a reactive patient to a proactive healthcare consumer.

Over 70% of our sales currently come from our consumer healthcare products. We have the ability 
to develop these products further and this will be our focus going forwards.

The words ‘positive difference’ refer to the maintenance, treatment or improvement 
of any aspect of a consumer’s health & wellbeing, so that they perceive it to be 
better than it was before.

In considering our future performance we will take account of:

 ›
 ›
 ›
 ›

the rate of growth achieved by our priority brands, relative to their respective categories;
external expectations of our sales and profit growth;
how we are rated by our strategic partners; and
how we are rated by our employees.

By leading, trusted and proven brands, we mean brands with a strong point of difference, that are 
leaders in their field, and have a proven track record of delivering on their claims.

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Managing our packaging estate 

31

Developing our response to  
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TCFD 

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35

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42

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O U R   S T R A T E G Y

Our vision is to be a high performing  
consumer healthcare company, built on a  
portfolio of leading, trusted and proven brands 

EVOLVING OUR STRATEGY TO DELIVER AGAINST  
OUR REFINED VISION AND PURPOSE
Throughout this year we have refined our purpose, vision and 
strategy to align with our transformation to a predominantly 
consumer healthcare company. We have also worked to evolve 
our strategy to better position the Company for the years ahead, 
and in response to changing underlying market dynamics. 

Helping damaged skin
Within the multi-billion-dollar global skincare category there are 
several skin health sub-categories, such as scar management, 
medicated anti-dandruff shampoo and dry skin – sub-categories 
which are both fast growing at present and have large future 
growth potential thanks to favourable demographics and high 
global prevalence of these conditions. 

Our previous strategy focused on delivering organic growth 
in our key brands (broadly defined as our larger Consumer 
Healthcare brands) and complementary acquisitions, focused in 
the Consumer Healthcare space, whereas our updated strategy 
provides a more targeted approach. We’ve now identified the 
key categories in which we want to focus, both from a category 
and geographical perspective, which allows for a clearer 
definition of the acquisitions we will seek.

Our strategy will now focus on the global priority categories of 
helping damaged skin and supporting healthy ageing.

 See our evolved strategy infographic on page 15

Alliance already has brands, products, technology, and expertise 
within these high-growth sub-categories – brands that are 
grounded in science, which we can build and develop further,  
to make a positive difference to more people’s lives globally.

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06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
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TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

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O U R   S T R A T E G Y   C O N T I N U E D

Supporting healthy ageing
The favourable demographics of the ageing global population 
are expected to continue, with forecasts predicting that an 
additional quarter of a billion people (or 40% of the global 
population) will be over the age of 45 by 2030. The 65+ age 
group is growing consistently faster than any other age group,  
as medical advances facilitate longer lifespans.

Brands falling within the categories of Helping damaged 
skin, and Supporting healthy ageing will be the focus of our 
innovation and future acquisition activities going forwards.

In addition, we have a number of high performing local 
brands and critical medicines, which are central to the 
delivery of our purpose. 

High performing local brands

We have a number of high performing local brands which 
continue to provide a strong contribution to the business and so 
warrant specific local focus and investment. These brands deliver 
significant sales in a market or region and have the potential to 
deliver good regional growth.

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Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
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TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
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As people become increasingly proactive in managing their 
health, we anticipate sustained growth in those healthcare 
categories that support healthy ageing. This includes managing 
conditions that arise as a result of the ageing process, such as 
menopause, or age-related macular degeneration (‘AMD’), and 
also long-term conditions which can occur at any age, where we 
can support an individual’s health and wellbeing over a longer 
period of time. 

Critical medicines
Critical medicines are for conditions that are life-threatening or 
where patients’ physical or mental health would be seriously 
impacted without the product and there are no viable alternatives.

We see it as part of our social responsibility to ensure that our 
critical medicines continue to be made available to patients, 
and it is this, rather than financial returns or growth potential, 
which underpins our resource allocation decisions for this 
group of products.

Foundation brands
We continue to review the future of those smaller brands which 
have lower contribution to our bottom-line performance, and 
which may have higher associated risks and, if appropriate,  
will look to discontinue or divest these.

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Strategic Report
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Market Overview 

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Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

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47

O U R   S T R A T E G Y   C O N T I N U E D

Core priority markets
Since 2016, and aligned with our period of expansion through 
acquisition, we have been building the optimal global office 
base to support our future growth. We remain fully committed to 
this global footprint.

We will continue to manage and drive growth from our eight key 
regional offices located in Paris, Düsseldorf, Madrid, Dublin, Cary, 
Singapore, Shanghai, and our headquarters in Chippenham.

From this fixed base of offices, we will service and grow our 
business globally, with particular focus on our identified Core 
Priority markets: 

 ›

 ›

The US, China and UK will continue to be our highest 
priority geographies – these are markets where there 
remains significant growth potential and where we have 
existing scale.
France and Germany offer attractive OTC markets, and whilst 
our revenue generation in these markets is relatively low at 
present, our direct presence and high-quality local teams 
provide the potential to drive both scale and growth.

Collectively, these five markets currently account for around 
75% of our annual sales. Our remaining markets will continue to 
provide profitable incremental business.

4

2

1

3

5

8

7

6

Geographic key

International offices

For more information visit  
alliancepharmaceuticals.com

4 Düsseldorf, Germany

Core priority markets

Other markets

1

2

3

Dublin, Republic of Ireland

Paris, France

Global Head Office: Chippenham, UK

5 Madrid, Spain

6

7

8

Singapore 

Shanghai, China

Cary, North Carolina, USA

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Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

T H E   E V O L U T I O N   O F   O U R   S T R A T E G Y

Previous strategy:

Core strategy:

Revised strategy:

Market (category) focus:
Our revised strategy focuses on the global priority categories of helping damaged skin  
and supporting healthy ageing

Helping damaged skin

Supporting healthy ageing

Organic growth –  
Key brands

Complementary  
acquisitions

Supported by:

High performing local brands

Critical medicines

Underpinned by:

Investing in people

Sustainability

Strategic priorities:
These are the four focus areas that will enable the successful delivery of our strategy

For more information visit  
alliancepharmaceuticals.com

These elements have now been embedded in our strategic priorities

Brand 
growth

Commercial 
execution

Strategic supply 
partnerships

Organisational 
agility

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O U R   S T R A T E G I C   P R I O R I T I E S

To enable the successful delivery of our new strategy, we have identified four priorities for the business over the next three to five years:

We will seek to enhance the attractiveness of 
our high value brands, through:

 ›

 ›

 ›

insight-led, data-driven, measurable 
marketing investment;
acquisition and in-licensing of products or 
technologies to support our key brands; and
innovation and development activity to 
keep our core brand portfolios ahead of 
their respective competitive sets.

In 2022, we successfully rolled out our new, 
reinvigorated marketing strategy for Nizoral™

  See our Spotlight on marketing excellence  
on page 18

We also saw £1.7m of sales generated from  
new innovation projects, including the 
expansion of our Kelo-Cote™ range with the 
launch of Kelo-Cote™ Kids.

  See our Spotlight on innovation and 
development on page 20

And we completed the acquisition and 
successful integration of ScarAway™ and the  
US rights to Kelo-Cote™, widening the reach  
of this key brand franchise and bolstering our 
presence in the US 

  See our Spotlight on ScarAwayTM and  
Kelo-CoteTM US acquisition on page 22

We will continue to look for omni-channel 
presence in our core markets whilst recognising 
that e-commerce represents our fastest growth 
channels in these markets, a trend which we 
expect to continue for many years to come.

In 2022, more than a third of our consumer 
healthcare sales were via e-commerce, which 
is significantly more than the global average for 
consumer healthcare, of around 13%. 

We believe that by 2027, this will have 
increased to around 40 – 45% of our total 
consumer healthcare sales.

Cross-border e-commerce (‘CBEC’) 
continues to be an important contributor to 
Kelo-Cote™ sales in China, both through the 
B2B and B2C channels.

Brand growth
We will build fast growing 
brands where consumer 
choice is driven by the positive 
difference we make

Commercial 
execution
We will increase the impact of  
our commercial execution, with  
a major focus on eCommerce 

  See our CEO 
Review on  
page 06

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Market Overview 

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Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
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Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
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Strategic Report
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Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
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O U R   S T R A T E G I C   P R I O R I T I E S   C O N T I N U E D

Partners who will support us not just with the 
manufacture and supply of current products, 
but also with innovation and the delivery of  
our environmental sustainability strategy.  
A smaller network of partners will also  
facilitate efficiency gains.

2022 was a challenging year for our 
operational teams, with inflation and the 
war in Ukraine impacting the costs and 
availability of raw materials, componentry, 
and transportation. This resulted in longer lead 
times, and challenged our ability to ensure on-
time-in-full delivery to our customers.

Going forward, we are looking to 
consolidate our supply chain, moving to a 
smaller, high-performing network of strong 
partners with whom we can collaborate and 
invest for the future. 

Strategic supply 
partnerships
We will transform our supply chain  
by investing in a network of  
strategic partnerships 

It is the diverse combination of skills, experience 
and energy of Alliance’s people that help to 
create our strong culture. We will be harnessing 
this culture to enable the successful delivery  
of our new strategy with increased focus  
and pace. 

Agile businesses are tuned in to the dynamic 
external world and centred on their customers’ 
changing needs. They have a rapid cycle of 
ideas development – a test, learn and adapt 
approach, which we believe is well-suited to 
areas such as innovation and e-commerce.

We recognise that new technologies, 
approaches, and opportunities enable 
companies to gain competitive advantage 
quickly – innovation and e-commerce 
require us to excel in these fast-moving, 
competitive worlds. Change is continual and 
as the pace of change increases we need 
to ensure we maintain sufficient agility to 
respond appropriately.

In October 2022, we held our first ever global 
employee conference, at which we shared 
our new purpose, vision and strategy with 
our employees from around the world, as a 
precursor to the development of the detailed 
operational plans which will enable us to 
deliver our refined strategic priorities.

Organisational 
agility
We will continue to cultivate an  
agile organisation and culture  
that delivers our growth 

  See our 
Sustainability 
overview on 
page 30

  See our Spotlight on 
culture, people and 
values on page 24

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ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

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18

20

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Managing our packaging estate 

31

Developing our response to  
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TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

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S P O T L I G H T   O N …

Marketing excellence 

Reinvigorating a  
heritage brand

Nizoral™, or Triatop™ as it is known in China, is a brand 
with over 40 years’ heritage in the Asia Pacific region. 

c. $240m

4% p.a.

VALUE OF THE MEDICATED 
ANTI-DANDRUFF MARKET  
IN APAC1

FORECAST MARKET GROWTH 
RATE TO 20251

For more information visit  
alliancepharmaceuticals.com

1 Nicholas Hall.

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“ Our deep understanding of 

our target consumer’s attitude 
and behaviours allowed us to 
develop an effective campaign 
across all key markets.”

Ambrose Peng, Global Marketing Manager –  
Nizoral™/Triatop™

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Managing our packaging estate 

31

Developing our response to  
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S P O T L I G H T   O N …  M A R K E T I N G   E X C E L L E N C E  C O N T I N U E D

When Alliance acquired Nizoral™ in the APAC region in 2018, 
it had been deprioritised by its former owners and had received 
little by way of marketing investment for several years. As a result, 
whilst it still had a loyal following amongst older consumers, a 
whole generation of younger consumers were largely unaware 
of the brand.

Using the results from our extensive consumer insight research, 
we developed a consumer-focused regional campaign, 
partnering with our local distributors and agencies to tailor 
the execution of this by country – for example, using leading 
basketball players to promote the brand on social media in 
the Philippines, a greater reference to scientific evidence in 
China and a more light-hearted, humorous approach  
in Australia. 

As a result, we have seen double-digit revenue growth this 
year in China, Australia and the Philippines.

The challenge for Alliance was therefore to design a new 
marketing approach to target this younger demographic, which 
promoted the product through an appropriate channel mix and 
emphasised key points of differentiation over its competitors in a 
contemporary, culturally relevant way.

For more information visit  
alliancepharmaceuticals.com

MARKET LEADER WITH

52%

SHARE IN AUSTRALIA2

2  Iqvia.

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Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
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TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

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47

S P O T L I G H T   O N …

Innovation and development

Our new I&D platform 
gets off to a strong start! 

April 2022 saw the launch of Kelo-Cote™ Kids – the first 
product from our new innovation platform – and a great 
example of how, through thinking creatively, we were able to 
extend the reach of our leading brand (Kelo-Cote™ scar gel) to 
a new audience – parents with children.

96%

OF PARENTS IN CHINA, WITH A 
CHILD WHO HAS EXPERIENCED 
SCARS, ARE LOOKING TO TREAT1

39%

MARKET SHARE 
AT DECEMBER 20222

For more information visit  
alliancepharmaceuticals.com

1 CLEAR consumer research, China, September 2021.

2 Brand value share – Scar kids segment - China, Nint, December 2022.

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ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

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35

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47

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S P O T L I G H T   O N …  I N N O V A T I O N   A N D   D E V E L O P M E N T  C O N T I N U E D

Kelo-Cote™ Kids product launch – April 2022
Through our research1, we discovered that in China: 

 › 60% of parents have children who have experienced  

scars in the last year

 › Of those, 96% are looking to treat
 ›

Safety, quality and efficacy are the key factors in parents’  
purchasing decisions

 › 24% of parents were already using Kelo-Cote™ to treat  

their children's scars

Since its launch in April 2022, Kelo-Cote™ Kids has enjoyed 
rapid market share growth, to command a 39% share of the 
market by value2 in December 2022, with limited cannibalisation 
of core product sales. It is now being marketed both through our  
Kelo-Cote™ CBEC flagship store in China and through local 
domestic channels.

“ Since its launch, Kelo-Cote™  

Kids has enjoyed rapid  
market share growth,  
to command a 39% share  
of the scar kids market in China.”

Natalie Bayes, 
Global Senior Brand Manager –  
Kelo-Cote™

In 2023, we plan to roll out the product to more markets.

This is a great example of how our new I&D platform has 
enabled us to deliver relevant consumer innovation, whilst also 
strengthening our lead brand, Kelo-Cote™.

New packaging, with fun otter characters designed to appeal 
to parents and children, enabled us to highlight those product 
claims which were most relevant to this audience:

 › Helps soften and flatten scars
 › Helps reduce redness and itching
 ›
 ›

Suitable for sensitive skin
Suitable for 3+ months 

For more information visit  
alliancepharmaceuticals.com

1 CLEAR consumer research, China, September 2021.

2 Brand value share – Scar kids segment - China, Nint, December 2022.

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Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

S P O T L I G H T   O N …

ScarAway™ and Kelo-Cote™ US acquisition

A highly strategic acquisition

Alliance’s acquisition of ScarAway™, the second largest brand in the 
US scar treatment market, and the US rights to Kelo-Cote™ in March 
2022 is a great example of how we’ve executed our strategy to 
deliver growth through selective, complementary acquisitions. 

c. $90m

28%

VALUE OF US SCAR  
TREATMENT MARKET1

SCARAWAY’S™ SHARE  
OF THIS MARKET1

For more information visit  
alliancepharmaceuticals.com

1 IRI and Jungle Scout.

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S P O T L I G H T   O N …  S C A R A W A Y ™   A N D   K E L O - C O T E ™   U S   A C Q U I S I T I O N  C O N T I N U E D

This acquisition created scale in the US, the largest consumer 
healthcare market in the world, enabling us to leverage the 
operating platform we’d created following the Vamousse™ 
and Amberen™ acquisitions, and completed our ownership of 
the worldwide rights to Kelo-Cote™, thereby creating our first 
global brand.

ScarAway™ also provided the opportunity to offer a silicone 
sheet in addition to a gel formulation in the US – both of which 
are universally considered first-line prophylactic and treatment 
options for hypertrophic scars and minor keloid scars.

Following rapid integration of the acquired business in just 
four months, our subsequent focus has been on leveraging the 
brands’ existing distribution network, consolidating supply-
side relationships, and increasing investment to drive further 
growth. New, modernised packaging is in development and 
is scheduled for launch in 2023, alongside a comprehensive 
consumer marketing campaign and new product development 
to accelerate market share gains.

“We were able to integrate 
the ScarAway™ acquisition 
in just four months, 
establishing a process 
which should make future 
integrations more efficient.”

Amanda Sicvol, Head of North America

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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24

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

S P O T L I G H T   O N …

Culture, people and values

Ensuring our people and culture  
continue to support the business’s 
medium-term growth ambitions

In 2022, we welcomed a record 80 new colleagues 
into the business, introduced new early careers 
schemes and held our first all-employee conference.

285

TOTAL EMPLOYEES1
2021: 245

82%

SAY THIS IS A GREAT 
PLACE TO WORK2
2021: 81%

For more information visit  
alliancepharmaceuticals.com

1 As at 31 December.

2 Based on findings from Great Place to Work® survey, October 2022.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

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Financial Statements

Additional Information

25

S P O T L I G H T   O N …   C U L T U R E ,   P E O P L E   A N D   V A L U E S  C O N T I N U E D

ORGANISATIONAL DEVELOPMENT
The continued expansion of our US team through 2022, initiated 
in response to the Amberen™ acquisition in 2020, followed by 
ScarAway™ and the US rights to Kelo-Cote™ in March 2022, 
means that we now have an experienced multi-functional team 
in the US, dedicated to supporting the growth of our growing 
portfolio of US-based brands, with a strong focus on innovation.

MOVING FORWARDS
Our new focus on organisational agility as a key enabler to 
the delivery of our strategy will require an increase both in 
focus and in pace – harnessing the skills, experience and 
energy that exists in our business, together with our culture 
of resilience, teamwork and collaboration, to enable us to 
respond to new challenges as they arise.

We also continued to support early career development, through 
the launch of our graduate development programme in the 
UK, bringing two graduates into our Commercial and Scientific 
Affairs teams, along with a year in industry placement student 
into our Group Finance function.

STRENGTHENING OUR EMPLOYER BRAND
This has been a major focus for us during 2022, as the 
competition for talent has intensified, leading to challenges in 
filling some specialist roles. We continue to provide a compelling 
career proposition and attract high calibre candidates with our 
strong positive culture and team ethos.

Throughout 2023, we will be focusing on building our innovation 
capability, processes and agility.

Progress in 2022:
 › 80 new joiners integrated into the business, 18 of whom 

joined in newly created roles
Improved GPTW survey outcomes, with additional 
certifications obtained in the US and France
Supplier selection completed for our new HR system

 ›

 ›

EMPLOYEES BY GENDER1

BOARD & SENIOR LEADERSHIP TEAM

78%

MALE
(2021: 80% Male 20% Female)

22%

FEMALE

SENIOR MANAGERS2,3

69%

MALE
(2021: 78% Male 22% Female)

31%

FEMALE

ALL EMPLOYEES4

42%

58%

FEMALE

EMPLOYEE ENGAGEMENT5

SURVEY  
RESPONSE RATE

87%

(2021: 74%)

OVERALL TRUST  
INDEX© RATING

79%

(2021: 76%)

Focus for 2023:
 › Developing agile ways of working within our Innovation 

MALE
(2021: 42% Male 58% Female)

and Development team

 › Continuing to strengthen our employer brand to attract 

 ›

and retain talent
Enhancing our internal communications, to increase 
connection throughout the business

 › Completing the implementation of our new HR system

Footnotes: 

1 As at 31 December.

2 2022: n=9 (2021: n=10).

3 Defined as those running major divisions of departments, but not part of the management 

team; 2022: n=29 (2021: n=27).

4 Including NED and fixed-term contractors.

5 As measured by the Great Place to Work® survey.

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S P O T L I G H T   O N …  C U L T U R E ,   P E O P L E   A N D   V A L U E S  C O N T I N U E D

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

All together in Bath – 
reconnecting post-pandemic

Maintaining cultural cohesion and connectivity 
has always been really important to us – 
particularly following the adoption of hybrid 
working, which rapidly became the norm post-
pandemic. It was this desire for connection 
which led to the decision to hold our first global 
employee conference in 2022.

In addition to giving all our colleagues around the world the 
opportunity to come together in person to network and share 
ideas, the conference also enabled us to discuss our updated 
purpose, vision, and strategy with all our employees, listen to 
their feedback and start to build collective understanding around 
some of the operational challenges we will need to address as 
we look to implement this revised strategy.

It was a great way to meet new colleagues and strengthen 
personal connections across the business, particularly given the 
high number of new recruits over the past couple of years, and 
the limited opportunities for in-person connection during the 
global pandemic.

Sustainability was very much front of mind, both in the 
conference content and organisation – from a lunchtime ‘pop up’ 
to increase employee awareness and engagement around our 
sustainability strategy, to the catering and travel arrangements for 
the conference itself.

Our first global conference was very well received by 
colleagues, and we’re sure that the benefits in terms of increased 
understanding, cultural alignment and connection, will continue 
to prevail through the organisation for many years to come.

For more information visit  
alliancepharmaceuticals.com

246

CONFERENCE ATTENDEES

>90%

OF ELIGIBLE ATTENDEES

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K E Y   P E R F O R M A N C E   I N D I C A T O R S

FINANCIAL KPIs

We set out here  
our key financial  
performance measures.
These are the primary 
measures used by 
management to monitor 
business performance,  
against both short-term 
budgets and forecasts and 
longer-term strategic plans.

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

1 These measures constitute Alternative Performance Measures 
(‘APMs’), as defined in note 31 to the Financial Statements.

2 Leverage is defined as: Adjusted net debt/enlarged Group 
EBITDA, calculated using pro forma EBITDA on a trailing 
12-month basis for acquired entities, in line with our  
banking covenants.

3 Basis points.

SEE-THROUGH REVENUE1

GM%: (OVERALL)

£172.0m +1%

(2021: £169.6m)

59.1% -540bp3

(2021: 64.5%)

UNDERLYING EBITDA1

£39.2m -19%

(2021: £48.6m)

2022

2021

2020

2019

£172.0m

£169.6m

£137.5m

£144.3m

2022

2021

2020

2019

59.1%

64.5%

60.2%

59.7%

2022

2021

2020

2019

£48.6m

£39.2m

£38.6m

£39.4m

UNDERLYING PROFIT BEFORE TAX

UNDERLYING BASIC EPS

£30.3m  -28%

(2021: £42.2m)

4.28p -33%

(2021: 6.39p)

DIVIDEND PER SHARE

1.776p +5%

(2021: 1.691p)

2022

2021

2020

2019

£30.3m

£33.5m

£32.9m

£42.2m

2022

2021

2020

2019

4.28p

5.11p

5.09p

6.39p

2022

2021

2020

2019

0.536p

1.776p

1.691p

1.610p

FREE CASH FLOW1

£15.8m  -48%

(2021: £30.2m)

LEVERAGE2

2.57x

(2021: 1.73xx)

NET DEBT1

£102.0m  +17%

(2021: £87.0m)

2022

2021

2020

2019

£15.8m

£30.2m

£34.1m

£29.1m

2022

2021

2020

2019

2.57x

2.43x

1.73x

1.48x

2022

2021

2020

2019

£102.0m

£87.0m

£109.4m

£59.2m

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Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

K E Y   P E R F O R M A N C E   I N D I C A T O R S   C O N T I N U E D

ADDITIONAL KPIs

WORKING CAPITAL MANAGEMENT

PORTFOLIO EVOLUTION

RESOURCING

SUPPLIER PAYMENT DAYS1

58 +12 days

(2021: 46)

REVENUE: CONSUMER HEALTHCARE BRANDS4

TOTAL HEADCOUNT5

£125.2m  +3%

(2021: £121.8m)

285 +16%

(2021: 245)

2022

2021

2020

2019

58

46

52

41

2022

2021

2020

2019

£125.2m

£121.8m

£93.0m

£92.4m

2022

2021

2020

2019

285

245

245

214

DAYS SALES OUTSTANDING2

71 +10 days

(2021: 61)

2022

2021

2020

2019

CONSUMER HEALTHCARE AS A % OF TOTAL REVENUE4

EMPLOYEE ENGAGEMENT: (GPTW Trust Index©)

73% +1%

(2021: 72%)

79% +3%

(2021: 76%)

71

55

61

61

2022

2021

2020

2019

73%

72%

68%

64%

2022

2021

2020

2019

N/A

79%

76%

79%

DAYS INVENTORY ON HAND3

154 -15 days

(2021: 169)

2022

2021

2020

2019

154

169

138

128

1 Month-end value of trade payables relative to the trailing 12 

months cost of goods expressed as a days’ equivalent, averaged 
over the year.

2  Month-end value of trade receivables relative to the trailing 12 months 

sales expressed as a days’ equivalent, averaged over the year.

3 Month-end value of inventory relative to the trailing 12 months cost 
of goods expressed as a days’ equivalent, averaged over the year.

4 See-through basis.

5 As at 31 December.

Other measures
In addition to the measures disclosed 
above, we also employ a broad range of 
other measures to help us manage business 
performance, including but not limited to: 

 ›

 ›

Brand revenues, margins and contribution, 
by management region and relative to 
marketing and innovation investment
Post-acquisition performance evaluation 
measures

 › On-time in-full delivery and out-of-stocks 
(to ensure continuity of product supply)

 › Additional detail around inventory 

levels, provisioning and ageing profile; 
trade receivables and payables levels 
and ageing profiles (working capital 
management)

We do not disclose the related metrics 
associated with these measures, on the basis 
that they are commercially sensitive and/or 
intended for internal use only.

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29

S U S T A I N A B I L I T Y

Prioritising people, 
planet and product

Our approach
We are committed to operating our business in a responsible 
way, which minimises negative impacts on people and planet, 
makes a positive contribution to society and promotes the 
sustainability of our business for the longer term.

Our sustainability framework
Our sustainability framework identifies the key areas we are 
focusing on, to deliver our purpose and to assure the future of  
our business for the longer term.

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

PEOPLE
 Read about  
Our People Story  
on page 30

PURPOSE
 Read about  
Our Purpose  
on page 11

PLANET
 Read about  
Our Planet Story  
on page 30

Visit our Sustainability hub
Learn more about how our framework has evolved, and our 
approach to materiality and governance on our website 
alliancepharmaceuticals.com/sustainability

For more information visit  
alliancepharmaceuticals.com

  Read about how we have delivered against our 
sustainability commitments on page 30 and in 
our Online Sustainability Report on our website

PRODUCT
 Read about Our Product Story  

on page 30

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

30

S U S T A I N A B I L I T Y   C O N T I N U E D

Overview

We have made good progress against our sustainability agenda in 2022 – below is a summary of our key achievements in the year and our main areas of focus for 2023.

Further detail, including relevant metrics for all the areas of focus forming part of our sustainability framework, can be found in our Online Sustainability Report. 

Identified focus areas for 2022

Progress in the year

Focus for 2023

PEOPLE
Continued investment in capability 
development, to ensure our resourcing 
supports our growth ambitions.

Continued focus on cultural development and 
employee engagement.

Ensuring that our employees continue to have  
a good understanding of, and comply with,  
all relevant ethical business practices.

PLANET
Environmental strategy development – 
developing our carbon action plan and  
our response to climate change.

Packaging lifecycle management –  
strategy development and target setting.

 › 80 new heads brought into the business in 2022 – 18 of which were in newly created roles 
 › New UK graduate and industry placement schemes rolled out
 › High levels of employee engagement maintained with increased GPTW survey participation 

and trust index ratings; additional certifications achieved in US and France

First all-employee conference held

 ›
 › More targeted approach to online compliance training, driving an increase in course 

completion rates 

 › Compliance training provision further enhanced through partnering with new external providers

 ›

Increasing our organisational agility – developing the 
requisite capabilities through a combination of talent 
acquisition, training, and cultural change

 › Maintaining and enhancing our high levels of employee 

engagement

 ›

Launching our employee code of conduct, setting the 
benchmark for the ethical behaviours we expect  
from colleagues

 › Offset Scope 1 & 2 UK emissions for 2021
 › Set Scope 1 & 2 net zero targets
 › Commenced initial engagement (‘fact find’) with all our contract manufacturers ('CMOs') and 
our top ten logistics partners to establish where they are on their climate change journeys
 › Undertook scenario analysis and risk assessment to support publication of first full TCFD report 

and disclosures

 › Gained greater understanding of the constituents of our packaging estate (primary and 

secondary) and the steps we need to take to promote circularity and reduce our use of single-
use plastics; pilot projects initiated to further understanding 

Continuing to work towards developing our Scope 3 
emissions reduction targets, through:

 ›

 ›

embedding ownership of product-related emissions 
within the appropriate functional areas of the business; 
and

continued methodology improvements to increase the 
accuracy of emissions measurement across all categories 

Continuing to develop our packaging strategy, confirming 
and publishing sustainability improvement targets for both 
primary and secondary packaging

For more information visit  
alliancepharmaceuticals.com

PRODUCT
Increasing the oversight we have of our 
supply chain; obtaining confirmation from our 
contract manufacturers and other suppliers 
that they comply with our ethical standards.

 ›

Partner code of conduct published, setting out the ethical expectations we have of our partners 
– be they CMOs, logistics service providers or distributors

 › Obtaining formal confirmation from our CMOs that they 

comply with our ethical standards

 ›

Tightening our processes around modern slavery in our 
supply chain

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S P O T L I G H T   O N …

Managing our packaging estate

Developing and implementing a sustainable packaging strategy, 
supported by appropriate targets and delivery plans, was one 
of the key focus areas we identified for 2022 to reduce the 
environmental impact of our product packaging.

We have made good progress in 2022 to build a better 
understanding of our primary and secondary packaging estate, 
and the associated challenges and opportunities it presents, 
although we are not yet in a position to publish targets relating to 
packaging sustainability.

Just over half of our packaging by weight is made up of paper, 
metal, and glass – materials for which there are already 
established circularity channels. Our focus will therefore be on 
leveraging these channels, through better labelling of recycling 
instructions on packs and the use of recycled and/or FSC-
certified paper for our secondary packaging and instructions for 
use sheets.

The remainder of our estate comprises plastics – primarily rigid 
plastics, such as bottles and jars. The recyclability of these varies 
both by product, and by country.

WHAT DOES OUR PRODUCT  
PACKAGING CONSIST OF?

THE DIFFERENT FORMATS THAT  
OUR PLASTIC PACKAGING TAKES

Metal  
10%

Glass
6%

Blister  
8%

Misc
2%

Paper  
38%

Tube  
10%

Plastic 
46%

Rigid 
80%

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate  31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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S P O T L I G H T   O N …  M A N A G I N G   O U R   P A C K A G I N G   E S T A T E  C O N T I N U E D

We have identified a number of avenues we will be exploring 
in 2023 to improve the environmental credentials of the plastics 
used in our packaging. These include: 

 ›

 ›

 ›

reducing overall consumption through ‘right sizing’ 
of components;
increasing component recyclability – through better labelling 
and the switch to materials that are more widely recycled;
replacing PVC/PVDC plastics with alternative materials, 
or formats; and

 › maximising the use of PCR content.

Blister packs present a particular challenge for us, and the 
pharmaceutical industry as a whole, as they comprise two 
different elements welded together, making them widely 
unrecyclable. These packs also contain harmful PVC. 

Elimination of polyvinylchloride ('PVC') and 
polyvinylidene chloride ('PVDC')
PVC and PVDC are widely used in the forming material 
for blister packs, as they’re low cost, have good barrier 
properties, and are easy to use. However, they are non- 
recyclable and their presence pollutes plastics recycling 
streams. When incinerated, they release chlorine into the 
atmosphere – or into the water table if sent to landfill.

Maximising the use of post-consumer recycled 
('PCR') plastics 
Whilst we will be looking to incorporate more PCR plastic 
in our packaging, the availability of PCR plastic suitable for 
use in consumer healthcare products is currently low, and 
what is available is of inconsistent quality and commands 
a higher price than the equivalent virgin material. Over 
time, the expectation is that progressive legislation will tax 
virgin materials to promote use of PCR, whilst high levels 
of investment in recycling technologies (mechanical and 
chemical) will improve the availability and competitiveness 
of high-quality PCR material.

We are excited by the potential to bring about positive 
change, through working in partnership with our suppliers 
to source new and better alternatives to some of our current 
packaging, in furtherance of our ambition to reduce our 
reliance on single-use plastics.

Pilot studies have been initiated to look at more sustainable 
packaging options for plastic tubes, rigid packaging, and blister 
packs. We expect these to be completed during the first half of 
2023 and the outputs from these projects will then inform the 
future development of our strategy.

We remain mindful of the need to balance environmental 
benefits with broader sustainability considerations within our 
supply chain, including cost, security of supply, and the maturity 
of associated technologies.

Whilst improving the environmental credentials of our packaging 
will help to reduce our end-to-end Scope 3 emissions – 
both those associated with the end-of-life treatment of our 
packaging, and the more significant emissions associated with 
its manufacture – collectively they only account for only c.10% 
of our total emissions and so will be a contributor to, rather than 
a key driver of, our wider Scope 3 product-related emissions 
reduction. 

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33

35

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42

47

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S P O T L I G H T   O N …

Developing our response to climate change

The scenario analysis and risk evaluation process has been a 
valuable learning experience for us, as we included not just 
our own operational sites, but also those of our larger CMOs, 
enabling us to make use of insights gained in relation to the 
resilience of our supply chain through COVID-19, and disruptions 
to global supply chains as a result of the war in Ukraine in our 
assessment of both physical and transition risks.

In 2023, we will look to deepen our relationships with our 
partners, in order to support the mutual dissemination of 
knowledge around climate risks and opportunities, and to  
better understand their emissions management strategies,  
as a precursor to developing our Scope 3 emissions targets. 

We will also be looking to extend our climate risk analysis to 
include other key partners in our value chain. 

In our 2021 Annual Report, we highlighted our ambition to 
progress towards full disclosure, in line with the Task Force on 
Climate-related Financial Disclosures ('TCFD') recommendations, 
in 2022. 

During the year we have worked with external consultants to 
support us with the evaluation of our business from a TCFD 
perspective and to undertake the scenario analysis and risk 
assessment required in order to determine our exposure to 
climate-related risks, considering both our own operations and 
the locations of our key supply partners.

As part of our journey to full TCFD compliance, we are proud 
to publish our extended voluntary disclosures for 2022 as part 
of this Report, with additional detail to be provided in our first 
stand-alone TCFD report, to follow shortly on our website. The 
disclosures are being made on a voluntary basis because, as a 
UK-registered company, with securities admitted to AIM, with 
less than 500 employees, we are currently outside the scope of 
the mandatory disclosure requirements. 

As a result of this process, and the associated climate scenario 
analysis and risk review, we have concluded that we should be 
recognising the impact of tackling climate change as a principal 
risk and it has therefore been added to our Principal Risks and 
Uncertainties coverage on pages 47-56.

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31

Developing our response to  
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TCFD 

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Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

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S P O T L I G H T   O N …  D E V E L O P I N G   O U R   R E S P O N S E   T O   C L I M A T E   C H A N G E   C O N T I N U E D

Setting (and delivering against) our Scope 1 & 2 
emissions targets
Midway through 2022, we set and published our Scope  
1 & 2 emissions targets:

 ›

To achieve a 65% reduction in our emissions (versus 2018 
baseline) by 2025, and to achieve net zero (90% absolute 
reduction) by 2030.

 › We used 2018 as our base year so we could demonstrate 

the significant reduction in emissions we’ve achieved already 
through environmental improvements to our Chippenham 
office HQ and to avoid using a base year in which use of the 
building was artificially low, due to COVID-19 restrictions.

The graphic below shows the trajectory of our emissions from 
2018 through 2021 (the latest data available at the time the 
targets were set), and the further reductions needed to reach 
our targets.

Our Scope 1 & 2 emissions for 2022 were 52 tCO2, a reduction 
of 26% versus those for 2021, due primarily to reduced 
consumption at our Chippenham HQ and the non-renewal of the 
lease for our leased office in Chester mid-way through the year.

We anticipate that further reductions in our UK emissions will be 
driven largely by own electricity generation at our Chippenham 
HQ, through the installation of PV roof panels, subject to receipt 
of all necessary consents.

120

100

80

2

O
C

t

60

40

20

0

Scope 1 & 2 emissions – progression and targets

Achieved to date: 38% reduction

Interim target: 65% reduction

Intensity reduction 2018–2021: 55%

Net zero target: 90% absolute reduction

2018

2019

2020

2021

2022

2023

2024

2025

2026

2027

2028

2029

2030

Electricity – UK

Electricity – international sites

Gas & other fuels – UK

Gas & other fuels – international sites

Target

Progression

Emissions intensity

Remaining 10% removed by offsets

Reductions in emissions at our international sites where we 
control the supply will be driven principally by switching to 
renewable tariffs.

We also expect to benefit from small reductions in consumption 
driven by energy-saving measures through increased colleague 
awareness and engagement across all our offices and from grid-
driven reductions in electricity tariffs.

1.00

0.90

0.80

0.70

0.60

0.50

0.40

0.30

0.20

0.10

0

t

C
O
2
/
£
m

r
e
v
e
n
u
e

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31

Developing our response to  
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33

35

40

42

47

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T A S K   F O R C E   F O R   C L I M A T E - R E L A T E D   F I N A N C I A L   D I S C L O S U R E S   ( T C F D ) 

We recognise that we have a role to play in reducing 
our environmental impact and our contribution to 
climate change. 

Whilst there is no current requirement for us to comply with 
the mandatory requirements of TCFD, we welcome the 
recommendations, and having published partial disclosures in 
our 2021 Annual Report, we are pleased to report voluntarily on 
our progress in 2022 in integrating climate considerations into 
our existing business strategy and risk management processes. 

In addition to the disclosures below, we plan to publish our first 
stand-alone TCFD report on the sustainability section of our 
website at the end of March 2023, to provide supplementary 
information around the risks and opportunities we face as a 
business as a result of climate change and how we plan to 
address these.

Governance – taking responsibility for climate-related risks 
and opportunities

Climate governance has been integrated into our existing 
corporate governance structures, with the Board having 
overall responsibility for Alliance’s response to climate 
change and providing oversight on climate-related risks and 
opportunities, whilst ensuring suitable management processes 
are integrated into future financial planning, business strategy 
and operations. The CEO is the Board Director responsible 
for sustainability and for ensuring communication between 
stakeholders, the Board, management, and employees 
around our climate action is ongoing.

The ESG Committee, which in 2022 comprised all Board 
members, is responsible for setting the Group’s overarching 
sustainability strategy, and for identifying relevant ESG priorities 
that most significantly impact the Group, including those relating 
to climate change. The Committee is also responsible for ensuring 

that climate change priorities are anchored as an integral part of 
the Company’s business strategy.

The ESG Committee has delegated management responsibility 
for climate-related risks and opportunities to the Senior 
Leadership Team ('SLT'), supported by the Corporate 
Sustainability Lead. Collectively, they ensure the development 
and implementation of the Company’s sustainability strategy, 
including climate action and TCFD reporting.

Throughout the year, members of the ESG Board Committee, 
SLT and wider management worked with third-party ESG 
specialists to identify and assess the impact of climate change 
on our business operations. A series of workshops were 
held to build internal capability across all levels within the 
organisation, as a precursor to the creation of a climate risk 
register, which will be reviewed and updated annually, to 
ensure climate risks and opportunities continue to be properly 
assessed, monitored, and reported.

Strategy – developing a resilient business strategy

We have a clear strategy to deliver sustainable business growth, 
through maximising the value of our core Consumer Healthcare 
business. Through implementing the recommendations of the 
TCFD, we have been able to identify the climate risks which may 
prevent us from successfully delivering our business strategy, 
together with opportunities to strengthen our position and 
deliver increased value for stakeholders. This forward-looking 
analysis has helped us consider climate change in our long-term 
planning, to ensure that our business strategy remains resilient to 
the impacts of climate change.

Our climate risk management process identified the climate-
related risks and opportunities, which could potentially impact 
our business. To strengthen this process, we utilised climate 
scenario analysis, investigating the resilience of our business 

strategy across differing future projections of climate events. 
Climate scenario analysis was conducted for all our operational 
sites with the exception of Dublin (due to its size), allowing us to 
assess the impact of climate change on our future operations.

The outsourced nature of our business means that we rely 
heavily on third-party partners, such as our distributors, contract 
manufacturers ('CMOs') and logistic service providers ('LSPs'). 
Any climate-related impacts on their operations could potentially 
present a significant risk to our business. We therefore widened 
our assessment of physical risks, through carrying out climate 
scenario analysis on 24 of our key supplier sites, to begin to 
understand how climate change may impact our value chain. We 
plan to extend this analysis further in 2023. 

Climate scenarios 
We considered three climate change scenarios, when evaluating 
the impact of each identified risk on our business operations and 
financial planning:

Below 2°C

 ›
 › 2–3°C
 › Above 3°C

With the warming pathways modelled over three time-horizons: 

Short-term (2022–2025) 
 ›
 › Medium-term (2025–2035) 
Long-term (2035–2050) 
 ›

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31

Developing our response to  
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33

35

40

42

47

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Strategic Report
Strategic Report
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Market Overview 
Market Overview 

 Our Strategy 
 Our Strategy 

Spotlight on…
Spotlight on…

Marketing excellence 
Marketing excellence 

Innovation and development 
Innovation and development 

ScarAway™ and Kelo-Cote™  
ScarAway™ and Kelo-Cote™  
US acquisition 
US acquisition 

Culture, people and values 
Culture, people and values 

Key Performance Indicators 
Key Performance Indicators 

Sustainability 
Sustainability 

Spotlight on…
Spotlight on…

06
06

09
09

12
12

18
18

20
20

22
22

24
24

27
27

29
29

Managing our packaging estate 
Managing our packaging estate 

31
31

Developing our response to  
Developing our response to  
climate change  
climate change  

TCFD 
TCFD 

Stakeholder Engagement 
Stakeholder Engagement 

Financial Review 
Financial Review 

 Principal Risks and Uncertainties 
 Principal Risks and Uncertainties 

33
33

35
35

40
40

42
42

47
47

T A S K   F O R C E   F O R   C L I M A T E - R E L A T E D   F I N A N C I A L   D I S C L O S U R E S   ( T C F D )   C O N T I N U E D

We considered both the short to medium-term risks and opportunities arising from the transition to a lower-carbon economy, together with our level of exposure to the longer-term physical risks associated 
with global warming. Through this process, we identified eight transition risks and two climate-related opportunities, which are outlined in the table below, together with their potential impacts, to the extent 
that we are able to quantify these. We also identified six physical risks which we will need to manage our exposure to in the longer term, which are also summarised below.

Transition risks

Area 

Risk 

Policy & Legal 

Increased regulation due to  
climate change

Scenario(s)

Timeframe

Impact description

Impact

Below 2°C and 2–3°C 

Short to Medium Term (2022–2035)  Expenditures – Increased operating costs 

Negligible/< £0.5m

(e.g. higher compliance costs)

Increase in carbon pricing

2–3°C 

Medium Term (2025–2035) 

Expenditures – Increased direct costs 

Negligible/< £0.5m

Mandates on and regulation of existing 
products and services

Below 2°C and 2–3°C 

Short to Medium Term (2022–2035)  Expenditures – Increased direct costs 

Negligible/< £0.5m

Market

Increased cost of energy and materials

Below 2°C, 2–3°C and >3°C

Short to Medium Term (2022–2035)  Expenditures – Increased indirect 

Small/£0.5m–£1.5m

(operating) costs

Reputation

Technology

Changing consumer preferences and 
increased sensitivity to ESG

Increased stakeholder concern  
damaging our reputation

Substitution of existing products with 
lower emissions alternatives

Costs to transition to lower emissions 
technology

Below 2°C and 2–3°C 

Short to Medium Term (2022–2035)  Revenue – Decreased revenue due to 

Small/£0.5m–£1.5m

reduced demand for products

Below 2°C and 2–3°C 

Short to Medium Term (2022–2035)  Capital and Financing –  

Small/£0.5m–£1.5m

Decreased access to capital

Below 2°C and 2–3°C 

Short to Medium Term (2022–2035)  Capex – Increased capital  

Small/£0.5m–£1.5m

expenditure / investment

Below 2°C and 2–3°C

Short to Medium Term (2022–2035)  Capex – Increased capital  

Negligible/< £0.5m

expenditure / investment

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Strategic Report
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Market Overview 
Market Overview 

 Our Strategy 
 Our Strategy 

Spotlight on…
Spotlight on…

Marketing excellence 
Marketing excellence 

Innovation and development 
Innovation and development 

ScarAway™ and Kelo-Cote™  
ScarAway™ and Kelo-Cote™  
US acquisition 
US acquisition 

Culture, people and values 
Culture, people and values 

Key Performance Indicators 
Key Performance Indicators 

Sustainability 
Sustainability 

Spotlight on…
Spotlight on…

06
06

09
09

12
12

18
18

20
20

22
22

24
24

27
27

29
29

Managing our packaging estate 
Managing our packaging estate 

31
31

Developing our response to  
Developing our response to  
climate change  
climate change  

TCFD 
TCFD 

Stakeholder Engagement 
Stakeholder Engagement 

Financial Review 
Financial Review 

 Principal Risks and Uncertainties 
 Principal Risks and Uncertainties 

33
33

35
35

40
40

42
42

47
47

T A S K   F O R C E   F O R   C L I M A T E - R E L A T E D   F I N A N C I A L   D I S C L O S U R E S   ( T C F D )   C O N T I N U E D

Climate-related opportunities

Area 

Opportunity

Timeline 

Impact

Products and 
Services

Development of new products or services 
through R&D and innovation

Medium (2025–2035) 

Increased revenue from an increase 
in demand for sustainable products

Energy 
resources

Use of lower-emission sources  
of energy

Short – Medium Term  
(2022–2035) 

Physical risks

Nature

Acute

Climate-related Risk 

Increased frequency and severity  
of flooding

Increased frequency of  
heatwaves/extreme heat

Scenario

Above 3°C

Above 3°C

We are not yet in a position to 
quantify this opportunity

Reduction in operating expenses 
because of increased efficiency (for 
example, energy costs)

Small/£0.5m – £1.5m

Timeline 

Exposure

Long Term (2035–2050)

Long Term (2035–2050)

Increased frequency of wildfires

Above 3°C

Long Term (2035–2050)

Chronic

Rising mean temperatures

Above 3°C

Long Term (2035–2050)

Sea level rise

Water stress

Above 3°C

Above 3°C

Long Term (2035–2050)

Long Term (2035–2050)

Seven of our offices and 21 supplier sites are situated in potential 
high flood risk zones

Seven of our offices and 20 supplier sites are situated in areas at 
high risk of experiencing rising temperatures

One of our offices and eight supplier sites are located in areas at 
high risk of wildfire impact

Seven of our offices and 20 supplier sites will experience a 
significant increase in mean temperatures

Two of our offices and 11 supplier sites are potentially at risk from 
rising sea levels

Four of our offices and 12 supplier sites are located in areas likely to 
be subject to extremely high, or high, water stress by 2030

Additional details of our climate-related risks, scenario analysis and assessment processes underpinning these can be found in our 2022 TCFD report, which will be published shortly on our website.

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Market Overview 
Market Overview 

 Our Strategy 
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Spotlight on…
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Marketing excellence 
Marketing excellence 

Innovation and development 
Innovation and development 

ScarAway™ and Kelo-Cote™  
ScarAway™ and Kelo-Cote™  
US acquisition 
US acquisition 

Culture, people and values 
Culture, people and values 

Key Performance Indicators 
Key Performance Indicators 

Sustainability 
Sustainability 

Spotlight on…
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06
06

09
09

12
12

18
18

20
20

22
22

24
24

27
27

29
29

Managing our packaging estate 
Managing our packaging estate 

31
31

Developing our response to  
Developing our response to  
climate change  
climate change  

TCFD 
TCFD 

Stakeholder Engagement 
Stakeholder Engagement 

Financial Review 
Financial Review 

 Principal Risks and Uncertainties 
 Principal Risks and Uncertainties 

33
33

35
35

40
40

42
42

47
47

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T A S K   F O R C E   F O R   C L I M A T E - R E L A T E D   F I N A N C I A L   D I S C L O S U R E S   ( T C F D )   C O N T I N U E D

Risk Management – Embedding climate into our risk management framework 
At Alliance, we have an established and comprehensive risk management framework, which informs how business risks are identified, rated, and monitored. Through our TCFD programme, and with the 
support of third-party consultants, we have created a stand-alone climate risk management framework, to identify and assess our climate-related risks and opportunities, and then integrated this into our 
wider business risk management processes.

The creation of our climate risk management framework followed four key steps, to identify our risks, consider their potential impacts and identify current and future mitigation actions, to reduce their impact. 

1. Identify
 ›

internal stakeholder engagement 
programme created, to identify climate-
related risks which may impact our business 

2. Assess 
 ›

climate scenario analysis carried out to 
develop our understanding of climate 
change and how the identified risks and 
opportunities could potentially impact our 
business over time

3. Appraise
 ›

risk management options appraised, 
through a series of climate risk management 
workshops, to evaluate the effectiveness of 
the current mitigation actions

4. Address
 ›

identification and implementation of further 
mitigation actions to reduce climate change 
risk, as required

Going forwards, we will be reviewing our climate-related risks and opportunities annually, to monitor the performance of our mitigation plans and reassess the impact as appropriate. Responsibility for 
maintaining the climate risk register and for ensuring that climate risks and opportunities are accurately reviewed, reported, and monitored, sits with the SLT.

Following completion of the scenario analysis necessary to enable us to determine our potential level of exposure to climate-related risks – and the impact that these may have on our business, both in the 
short to medium term and in the longer term – we have taken the decision to recognise the impact of tackling climate change as a principal risk this year, rather than an emerging risk, as reported in our 2021 
Annual Report.

Metrics and Targets – Measuring and managing our climate impact
The primary metrics and targets we use to assess and manage relevant climate-related risks and opportunities are as follows:

Carbon emissions metrics

Emission Type

Scope 1 (direct)

Scope 2 (indirect)

Scope 3 (indirect)

Total

Emissions intensity*

* Defined as tCO2e per £m of revenue.

2022 Calculated Emissions (tonnes of CO2e)

2021 Calculated Emissions (tonnes of CO2e)

2020 Calculated Emissions (tonnes of CO2e)

Location-based

Market-based

Location-based

Market-based

Location-based

Market-based

2

50

47,973

48,025

279

2

52

47,973

48,026

279

2

68

37,648

37,627

128

2

16

37,648

37,575

128

64

89

32,243

32,396

128

–

–

–

–

–

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Marketing excellence 
Marketing excellence 

Innovation and development 
Innovation and development 

ScarAway™ and Kelo-Cote™  
ScarAway™ and Kelo-Cote™  
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Culture, people and values 

Key Performance Indicators 
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Sustainability 
Sustainability 

Spotlight on…
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06
06

09
09

12
12

18
18

20
20

22
22

24
24

27
27

29
29

Managing our packaging estate 
Managing our packaging estate 

31
31

Developing our response to  
Developing our response to  
climate change  
climate change  

TCFD 
TCFD 

Stakeholder Engagement 
Stakeholder Engagement 

Financial Review 
Financial Review 

 Principal Risks and Uncertainties 
 Principal Risks and Uncertainties 

33
33

35
35

40
40

42
42

47
47

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The increase in Scope 3 emissions from 2020 to 2021 was 
primarily due to increased activity levels following the easing of 
pandemic restrictions and the acquisition of Amberen™, coupled 
with an increased use of air freight versus sea freight to mitigate 
ongoing pandemic-related disruptions to supply chains and 
available logistics capacity.

The increase in Scope 3 emissions from 2021 to 2022 was 
driven by increases in emissions associated with contract 
manufacturer activity, logistics (upstream and downstream)  
and business travel.

Targets and progress
In September 2022, we set our Scope 1 & 2 emissions targets, 
to achieve net zero in 2030, with an interim target of 65% 
reduction by 2025, using 2018 as our baseline. More detail on 
our Scope 1 & 2 emissions targets and the progress we’ve made 
in delivering these can be found on page 34. 

We continued to evolve our data collection processes to improve 
the accuracy of our Scope 3 emissions in 2022, as a precursor 
to setting targets for specific categories of Scope 3 emissions in 
2023, as we look to further evolve our carbon action plan and 
climate change commitments.

Related reading:

 See ESG Committee Report on page 86

  See Spotlight on developing our response to climate change  
on page 33

  See Principal Risks & Uncertainties – impact of tackling climate 
change climate change on page 48

  See Streamlined Energy and Carbon Reporting (SECR) 
on page 90

Alliance Pharma plc Annual Report and Accounts 2022

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

40

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

S T A K E H O L D E R   E N G A G E M E N T

Engaging with 
our stakeholders

Overview
The Board recognises the importance of 
maintaining an engaged and motivated 
workforce, dependable supply chains, 
customer confidence in our products, close 
relationships with healthcare professionals, 
good returns for our shareholders and a 
positive contribution to both our local and 
wider communities. The Board works closely 
with the Senior Leadership Team to ensure we 
continue to understand and meet the evolving 
needs of all our stakeholders, whilst maintaining 
our relevance and ability to create long-term 
sustainable value.

On the following pages, we have identified 
our principal stakeholders, their primary 
requirements and how we’ve delivered against 
these in 2022.

Examples of how stakeholder interests have 
been considered by the Board in their decision-
making are provided in the Governance section. 

See Promoting the success of the company – s.172 
on page 67 

Additional content regarding our stakeholder 
relationships and how we manage these can 
also be found on our website.

SHAREHOLDERS

EMPLOYEES

CUSTOMERS 

Our shareholders are interested in:

Strong financial performance
Share price appreciation

 ›
 ›
 › Dividend income
 ›

ESG and long-term business 
sustainability 

How we delivered for our 
shareholders in 2022:
 › Dividend +5% vs 2021
 ›

Share price adversely impacted by 
financial performance
Refreshed purpose, vision and strategy 
Infrastructure strengthened; new 
people and skills brought into  
the business
Portfolio broadened through 
ScarAway™ acquisition in the US 

 ›
 ›

 ›

 › Good progress made with  

developing and executing our 
sustainability strategy

Our customers are looking for:
 ›

Safe and effective healthcare products, 
which are widely available, at a 
reasonable cost

How we delivered for our customers 
in 2022:
 ›

Safety and efficacy standards 
maintained (see Online Sustainability 
Report)

 › 44m units of product supplied
 › Continued channel expansion for our 
consumer products, particularly in 
e-commerce 
Pricing aligned with competitive 
positioning (consumer products)

 ›

Our employees are interested in:
 › Competitive reward structures
 › Opportunity to share in the success of 

the business
Flexible working

 ›
 › Meaningful work and connection
Learning and development 
 ›
opportunities

How we delivered for our 
employees in 2022:
 › Corporate bonus paid (for FY21)
 › Annual pay increase
 ›

Share options granted to all  
eligible employees
Flexible working arrangements 
maintained

 ›

 › Monthly business briefings 
 ›
Participation in GPTW survey
 › Global employee conference

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

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41

S T A K E H O L D E R   E N G A G E M E N T   C O N T I N U E D

SUPPLY AND DISTRIBUTION PARTNERS

HEALTHCARE PROFESSIONALS

LENDERS

WIDER COMMUNITIES

Our supply & distribution partners 
are looking for:
 › Continued business growth 

opportunities

How we delivered for our supply 
and distribution partners in 2022:
Supplier spend +39% vs 2021
 ›
>£70m of sales made via distributors  
 ›
in 2022

Healthcare professionals are 
looking for:
 ›

Engagement, education, information, 
and resources
Therapy area expertise

 ›

How we delivered for healthcare 
professionals in 2022:
 ›

Responses provided to more than  
900 enquiries from HCPs

Our lenders are interested in:
Strong financial performance
 ›
 › Ability to service & repay borrowings

How we delivered for our lenders in 
2022:
 › £15.8m of free cash flow generated
 › Compliance with borrowing  

covenants maintained

The wider community is interested in:
 ›
 ›
 › Charitable and product donations 

Social impact strategy
Local engagement

How we delivered for the wider 
community in 2022:
 › 12,000 units of product donated to 

International Health Partners, enabling 
149,000 treatments to be sent to  
10 countries around the world

 › £50k donated to Ukraine  
humanitarian appeal

 › Ongoing support of local charities  

and community events

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

42

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

F I N A N C I A L   R E V I E W

“ Whilst 2022 presented challenges in two 
discrete areas of the business, we worked 
hard to control costs and minimise the 
impact on underlying operating profit, 
whilst developing robust mitigation plans.”

Andrew Franklin, Chief Financial Officer

UNDERLYING EBITDA*

£39.2m

(2021: £48.6m -19%)

FREE CASH FLOW*

£15.8m

(2021: £30.2m -48%)

For more information visit  
alliancepharmaceuticals.com

* Non-IFRS alternative performance measures (see note 31).

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43

F I N A N C I A L   R E V I E W   C O N T I N U E D

SUMMARY UNDERLYING INCOME STATEMENT
Year ended 31 December

REVENUE SUMMARY
Year ended 31 December

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

See-through revenue*

Statutory revenue

Gross profit

Operating costs (including share-based employee 
remuneration)

Underlying EBITDA*

Depreciation and underlying amortisation

Underlying operating profit (EBIT)

Managing our packaging estate 

31

Finance costs

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

Underlying profit before taxation

Reported profit before taxation

Underlying basic earnings per share

Reported basic earnings per share

Proposed total dividend per share

2022  
£m

172.0

167.4

101.7

62.5

39.2

3.5

35.7

5.4

30.3

5.2

4.28p

0.17p

1.776p

2021 
 £m

169.6 

163.2

109.5

60.9

48.6

2.9

45.6

3.4

42.2

18.2

6.39p

1.37p

1.691p

Growth 

+1%

+3%

-7%

+3%

-19%

+20%

-22%

+57%

-28%

-71%

-33%

-88%

+5%

* The performance of the Group is assessed using Alternative Performance Measures (‘APMs’), which are measures that are not defined under 
IFRS, but are used by management to monitor ongoing business performance against both shorter-term budgets and forecasts and against 
the Group’s longer-term strategic plans. APMs are defined in note 31.

  Specifically, see-through revenue includes all sales from Nizoral™ as if they had been invoiced by Alliance as principal. For statutory 
accounting purposes the product margin on Nizoral™ sales made on an agency basis is included within Revenue, in line with IFRS 15.

  Underlying profitability metrics are presented as we believe this provides investors with useful information about the performance of the 
business. In 2022, underlying results exclude the amortisation and impairment of acquired intangible assets; in 2021, underlying results 
exclude the amortisation and impairment of acquired intangible assets, the CMA provision and restructuring costs. Further detail can be 
found in note 5.

For more information visit  
alliancepharmaceuticals.com

Kelo-Cote™ franchise

Amberen™

Nizoral™*

Other Consumer brands

Total Consumer Healthcare

Prescription Medicines

See-through revenue* 

LFL Consumer Healthcare see-through 
revenue*, excl. ScarAway™ & Kelo-Cote™ US

LFL see-through revenue*,  
excluding ScarAway™ & Kelo-Cote™ US

Statutory revenue – Consumer Healthcare

Statutory revenue – Group

LFL Consumer Healthcare statutory revenue, 
excluding ScarAway™ & Kelo-Cote™ US

LFL Group statutory revenue, excluding 
ScarAway™ & Kelo-Cote™ US

2022  
£m

50.0

14.9

21.8

38.4

125.2

46.8

172.0

118.9

165.7

120.6

167.4

114.3

161.1

2021 
 £m

48.8

19.2

20.6

33.2

121.8

47.8

169.6

121.8

169.6

115.4

163.2

115.4

163.2

Growth 

CER growth

+2%

-22%

+6%

+16%

+3%

-2%

+1%

-2%

-2%

+5%

+3%

-1%

-1%

-6%

-30%

+3%

+14%

-3%

-2%

-3%%

-7%

-6%

+3%

-2%

-6%

-5%

REVENUES
Group see-through revenue increased 1% to £172.0m (2021: £169.6m) and decreased 3% at 
constant exchange rates ('CER'). Like-for-like see-through revenue excluding ScarAway™ and 
Kelo-Cote™ US, acquired in March 2022, decreased 2% (-6% CER). Group revenue benefited 
from exchange rate movements in 2022, principally the weakening of Sterling against the US Dollar 
and HK Dollar, which increased see-through revenue by approximately £6.7m. Statutory revenue 
increased 3% to £167.4m (2021: £163.2m) (-2% CER).

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

44

F I N A N C I A L   R E V I E W   C O N T I N U E D

REVENUES CONTINUED
Consumer Healthcare 
Total Consumer Healthcare revenues for the year were 
£125.2m (2021: £121.8m), up 3% on the prior year (-3% 
CER) benefiting from the US acquisition in addition to 
currency tailwinds. On a statutory basis, reported Consumer 
Healthcare revenues were £120.6m, up 5% from the previous 
year (2021: £115.4m) and up 3% CER.

Excluding the impact of the US acquisition, like-for-like see-
through Consumer Healthcare revenue fell 2% (-7% CER) to 
£118.9m whilst on a statutory basis, like-for-like Consumer 
Healthcare revenues decreased 1% to £114.3m (-6% CER).

Kelo-Cote™ franchise– scar prevention and treatment 
Kelo-Cote™ franchise revenues grew 2% to £50.0m (2021: 
£48.8m) in the year, boosted by the US acquisition and currency 
gains (-6% CER). As previously reported, the cross-border 
e-commerce ('CBEC') scar treatment market declined during H1 
2022 as rigid lockdowns in China from March prevented the 
movement of product across the border from Hong Kong for a 
number of months. However, the online domestic market grew, 
and Kelo-Cote™ gained share. In H2 2022, a slower recovery 
in B2B demand for Kelo-Cote™ in the China CBEC channel, 
coupled with a one-off destocking effect in that channel, meant 
that like-for-like global Kelo-Cote™ revenues were down 17% 
CER in the year. 

End-consumer demand in the scar treatment market in 
e-commerce in China remains strong, with 7% value growth in 
2022 and Kelo-Cote™ gaining share. We continue to work with 
our CBEC distributor to develop further this channel, expand 
reach and optimise sales. Our B2C channel is well developed 
and in September our Kelo-Cote™ flagship online store was 
awarded a prestigious Tmall Global award, alongside a small 
number of other prominent brands, for surpassing RMB100m 

(c.£12m) in annual sales for the first time. We have refined our 
strategy to increase our presence in the significant B2B channel, 
which incorporates additional distributor support, and have 
successfully reduced the level of counterfeit product in the market. 

Looking ahead, we expect total Kelo-Cote™ franchise revenues 
to build throughout the year with overall growth anticipated to be 
above 20% in 2023, compensating in part for the one-off events 
which adversely affected revenues in 2022. This is slightly ahead 
of the 18% CAGR delivered for the four-year period ending  
31 December 2022, excluding the US acquisition.

Nizoral™ – medicated anti-dandruff shampoo 
Following the completion of the marketing authorisation transfer 
for Nizoral™ in China from Johnson & Johnson, we transitioned 
to a new top-tier local distributor at the end of H1 2022 to 
service the brand’s largest market. However phasing of orders to 
the new distributor led to a 12% decline in revenues in H1 2022.

Nizoral™ revenues recovered strongly in H2 2022, growing 
15% CER, partly due to the delayed orders from H1 falling 
into H2 and as Alliance finalised the remaining marketing 
authorisation transfers in Vietnam. Consequently, revenues 
grew 6% to £21.8m (2021: £20.6m) for the year (3% CER). The 
new Chinese distributor, and the completion of all marketing 
authorisation transfers, provides a very strong platform to 
drive high single-digit revenue growth for Nizoral™ in 2023, 
supported by new marketing initiatives and the introduction of 
updated packaging. 

Amberen™ – vitamin mineral supplement for the relief 
of menopause symptoms
Amberen™ generated net revenues of £14.9m (2021: 
£19.2m), 22% below prior year (-30% CER). Amberen™ sales 
performance was impacted by declines in the underlying 
bricks and mortar market due to an increase in prevalence of 
cheaper, white-label alternatives and customer switching to 

online platforms, in addition to the loss of a leading discount store 
account. Alliance is committed to improving the performance 
of Amberen™ in the higher-growth e-commerce channel, whilst 
optimising sales in bricks and mortar where appropriate. The 
brand’s packaging has been re-launched featuring stronger 
claims, and advertising investment continues, focused on digital, 
video, social media and search engine optimisation to drive 
share gains.

Amberen™ now has an enhanced platform from which to 
generate double-digit revenue growth on a like-for-like basis 
in 2023 and beyond. We are also focused on developing an 
innovation pipeline, to underpin the growth of the brand in 
the longer-term. Given the disruption to the bricks and mortar 
market, we now anticipate 2025 sales of c. £20m, below  
our original £35m expectation. As a consequence, coupled 
with higher interest rates, we have impaired the asset value  
by £12.0m.

Other Consumer Healthcare brands 
Our underlying business remains strong, with Other Consumer 
Healthcare revenues increasing 16% to £38.4m (2021: £33.2m) 
and 14% CER, with particularly strong growth from Aloclair™ 
and Vamousse™. This solid performance in our Other Consumer 
Healthcare brands clearly illustrates the benefits of a diversified 
portfolio, and we anticipate continued high single-digit growth 
in this portfolio of products in 2023, substantially ahead of the 
broader consumer healthcare market.

Prescription Medicines 
The Prescription Medicines business continues to deliver stable 
revenues with £46.8m (2021: £47.8m), in the year, down 2% on 
the prior year on both a reported and currency-adjusted basis. 
Key brands include Hydromol (emollient for the treatment of 
eczema), Forceval (nutritional supplement) and the Opus range 
of stoma care products, all of which performed well in the year.

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45

F I N A N C I A L   R E V I E W   C O N T I N U E D

We continue to actively manage this part of our portfolio, 
periodically discontinuing or disposing of smaller products that 
deliver very low sales and margins. However, the cash generation 
from these assets remains strong and, coupled with their limited 
requirement for promotional investment, this business continues to 
play an important part in our overall product portfolio. 

Operating performance
Whilst revenues increased 1% in the year, gross profit decreased 
7% to £101.7m (2021: £109.5m) due to a less favourable product 
mix with a lower proportion of Kelo-Cote™ and Amberen™ sales, 
and with Kelo-Cote™ generating a lower gross margin than in 
2021 due to a less favourable channel mix. Gross margin reduced 
by 540 basis points to 59.1% of see-through revenue (2021: 
64.5%) and gross margin relative to statutory revenue was 60.7% 
(2021: 67.1%).

Operating costs (defined as underlying administration and 
marketing expenses, excluding depreciation and underlying 
amortisation charges) increased 6% versus the prior year to 
£62.4m (2021: £58.6m) largely due to increased investment in 
marketing and employee costs to drive future growth, coupled 
with a modest increase in expenses to accommodate the US 
acquisition. As a result, operating costs as a percentage of sales 
increased 1.7% to 36.3% of see-through sales (2021: 34.6%).

With a lower share price in H2 2022 leading to a £2.2m reduction 
in share option charges versus prior year (2022: £0.1m, 2021: 
£2.3m) underlying earnings before interest, taxes, depreciation 
and underlying amortisation ('EBITDA') decreased 19% in the year 
to £39.2m (2021: £48.6m), whilst underlying operating profit 
('EBIT') decreased by 22% to £35.7m (2021: £45.6m). Reported 
operating profit decreased by £11.0m to £10.6m (2021: £21.6m), 
with non-underlying items of £25.1m (2021: £24.1m). 

Finance costs increased by £2.0m to £5.4m (2021: £3.4m), 
due to an increase in borrowing costs, reflecting both the rise 
in interest rates and an increase in the level of borrowings 
following the US acquisition.

The average interest charge on gross debt during the year 
(including non-utilisation fees) was 3.6% (2021: 2.2%).

The significant reduction in gross margin, in addition to the 
increase in operating and finance costs, led to a 28% decrease in 
underlying profit before tax to £30.3m (2021: £42.2m), resulting 
in a 730 basis point margin reduction to 17.6% of see-through 
revenues. Reported profit before tax decreased 71% to £5.2m 
(2021: £18.2m), primarily due to non-underlying amortisation 
and impairment charges. Further detail on non-underlying items is 
provided below and in note 5.

Depreciation and underlying amortisation
Depreciation and underlying amortisation charges for the 
year were £3.5m, up £0.6m on the prior year (2021: £2.9m), 
reflecting the first full year of amortisation of the ERP system.

Non-underlying items
Non-underlying items in the year principally comprised 
amortisation charges for Prescription Medicines and certain 
other brand assets, together with impairment charges identified 
as a result of the annual impairment review (see note 11). 

For 2022, impairment charges of £18.2m include £12.0m 
in relation to Amberen™, reflecting both the reduction in 
expected future cash flows, following the loss of a leading 
discount store account and more challenging trading 
conditions in the bricks and mortar market, and the higher cost 
of capital through increasing market interest rates.

For the prior year, non-underlying items comprised amortisation 
and impairment charges, together with a provision of £7.9m 
in relation to the Competition and Markets Authority ('CMA') 
decision (see note 20) and restructuring costs relating to the 
closure of our offices in Milan and Los Angeles. Further detail on 
non-underlying items is provided in note 5.

RECONCILIATION OF UNDERLYING TO REPORTED 
PROFIT BEFORE TAX 
Year ended 31 December

Underlying profit before taxation

Non-underlying items:

Amortisation of acquired intangibles

Impairment of intangible  
assets and goodwill

CMA provision

Restructuring costs

Other

Total

Reported profit before taxation

2022  
£m

30.3

(7.2)

(18.2)

–

–

0.4

(25.1)

5.2

2021  
£m

42.2

(7.2)

(6.2)

(7.9)

(2.4)

(0.4)

(24.1)

18.2

Taxation
The underlying tax charge for the year was £7.2m (2021: 
£8.0m), which equates to an underlying effective tax rate of 
23.9% (2021: 19.0%). The total tax charge for the year was 
£4.3m (2021: £10.8m), equating to an effective tax rate on 
reported profits of 82.0% (2021: 59.7%). The prior year figure 
includes a £5.0m charge following the increase in the UK tax 
rate from 19% to 25%, relating primarily to an increase in the 
deferred tax balances on intangible assets.

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Annual Report and Accounts 2022

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

46

Strategic Report
Strategic Report
 Chief Executive’s Review 
 Chief Executive’s Review 

Market Overview 
Market Overview 

 Our Strategy 
 Our Strategy 

Spotlight on…
Spotlight on…

Marketing excellence 
Marketing excellence 

Innovation and development 
Innovation and development 

ScarAway™ and Kelo-Cote™  
ScarAway™ and Kelo-Cote™  
US acquisition 
US acquisition 

Culture, people and values 
Culture, people and values 

Key Performance Indicators 
Key Performance Indicators 

Sustainability 
Sustainability 

Spotlight on…
Spotlight on…

06
06

09
09

12
12

18
18

20
20

22
22

24
24

27
27

29
29

Managing our packaging estate 
Managing our packaging estate 

31
31

Developing our response to  
Developing our response to  
climate change  
climate change  

TCFD 
TCFD 

Stakeholder Engagement 
Stakeholder Engagement 

Financial Review 
Financial Review 

 Principal Risks and Uncertainties 
 Principal Risks and Uncertainties 

33
33

35
35

40
40

42
42

47
47

For more information visit  
For more information visit  
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F I N A N C I A L   R E V I E W   C O N T I N U E D

Earnings per share
Underlying basic earnings per share, the measure used by the 
Board in assessing earnings performance, was 4.28p, a decrease 
of 33% on the prior year (2021: 6.39p), reflecting the decrease 
in the Group’s underlying profit after tax coupled with a modest 
increase in the number of shares in issue.

Inventories, net of provisions, increased £3.2m to £24.3m 
at 31 December 2022 (31 December 2021: £21.1m). This 
increase was due in part to the inclusion of inventory relating 
to ScarAway™ and Kelo-Cote™ US, coupled with increased 
inventory holdings to mitigate against both inflationary 
pressures and supply chain disruption. 

Reported basic earnings per share decreased by 88% to 0.17p 
(2021: 1.37p) due to a greater impact from non-underlying items 
on reported earnings in 2022 versus 2021.

Dividend
The Board is proposing a final dividend payment of 1.184p 
per share for 2022, an increase of 5% on the final dividend 
payment for 2021, taking the total dividend payment for the year 
to 1.776p (2021: 1.691p). The Board will continue to assess the 
level of future cash distributions having regard to overall business 
performance and future outlook.

The final dividend for 2022, subject to approval at the Company’s 
AGM on 25 May 2023, will be paid on 18 July 2023, to 
shareholders on the register on 23 June 2023. 

Balance sheet
Intangible assets increased by £7.9m in the year to £421.6m  
(31 December 2021: £413.7m). Of this, £15.2m relates to the US 
acquisition and associated distribution rights in March 2022, the 
remainder comprises the acquisition of an Aloclair™ brand asset 
for £1.2m, upwards revaluation adjustments linked to exchange 
rate movements of £18.7m, underlying amortisation charges 
of £2.0m, non-underlying amortisation charges of £7.2m, 
non-underlying impairment charges of £18.2m and £0.2m of 
additions to computer software assets. As noted above, £12.0m 
of the non-underlying impairment charges related to Amberen™.

Working capital
Net working capital at 31 December 2022 was £38.0m,  
an increase of £16.0m on that at the start of the year  
(31 December 2021: £22.0m), primarily reflecting  
movements in payables and receivables balances.

Alliance Pharma plc Annual Report and Accounts 2022

Receivables increased by £18.5m to £49.3m, reflecting 
the timing of sales and cash receipts in the second half of 
the year, versus the equivalent period in 2021. Payables 
increased by £5.7m to £35.6m, reflecting the phasing of 
invoices and payments around the year end, higher cost of 
sales and the increase in the year end inventory holding.

Provisions
Provisions decreased by £1.1m in the year, reflecting the utilisation 
of the restructuring provision for the closure of the Italy office. Of 
the £8.4m total provision, £7.9m relates to the CMA decision and 
£0.5m is the remaining restructuring provision. Further detail is 
provided in note 20.

Cash flow and net debt
Free cash flow (see note 31 for definition) for the year was 
£15.8m, in line with guidance given in the November Trading 
Update, but below the £30.2m reported in 2021, due to the 
weaker trading performance and the increase in working capital 
due to the timing of sales and cash receipts in the second half. 
Cash generated from operations decreased by 45% to £24.9m 
(2021: £44.9m).

Net debt increased by £15.0m to £102.0m at 31 December 
2022 (31 December 2021: £87.0m), reflecting both in-year 
cash generation and the $19.4m (£14.8m) US acquisition of 
ScarAway™ and the US rights to Kelo-Cote™, with Group 
leverage increasing to 2.57x (31 December 2021: 1.73x) and 
interest rate cover decreasing to 7.39 times (31 December 2021: 
14.34 times).

Net debt and Group leverage are both expected to fall 
during 2023, particularly in the second half, reflecting the 
Group’s anticipated strong cash generation, with Group 
leverage expected to be below 2.0x by the end of 2023.

Treasury and capital management
Group risk management policy is to hedge up to 75% of 
estimated future foreign currency EBITDA exposure, for up to 
the next 18 months at any point in time. The Group uses forward 
foreign exchange contracts to implement this policy, which are 
generally designated as cash flow hedges.

The Group benefits from a £165m Revolving Credit Facility ('RCF') 
and a £50m Accordion Facility, expiring in July 2024. Of this 
RCF, £29.9m, together with the whole of the Accordion Facility, 
remained unutilised as at 31 December 2022.

Borrowings are denominated in Sterling, Euro and US Dollars.

The cash generated from our trading operations is applied  
as follows:

 ›

 ›

 ›
 ›

in reinvesting in our current portfolio of brands, with 
investment being primarily targeted at our larger Consumer 
Healthcare brands;
in selectively acquiring and in-licensing products or 
technologies that support our key brands; 
in paying down debt; and
in paying dividends to our shareholders.

Andrew Franklin
Chief Financial Officer
20 March 2023

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

47

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S

Protecting our business

During the year, the Board reviewed the principal risks 
and uncertainties facing the Group and continues to 
focus on those which could threaten the sustainability 
of our business model, our reputation, future 
performance expectations, or in extreme cases, the 
solvency or liquidity of our business. The links between 
our principal risks and uncertainties and our strategy 
are set out in the table on pages 49 to 56.

Principal risks are assessed on a residual basis according to our 
current view of their potential severity (being the combination 
of impact and likelihood), and assuming that existing plans for 
mitigation are, and remain, effective. The current positioning 
of each of our principal risks, based on our assessment of their 
residual impact and likelihood, is shown in the graph to the right.

The identified risks are not intended to be an exhaustive list 
of all the risks the Group faces but are the principal risks and 
uncertainties which the Directors believe include all known 
material risks in relation to the Group and the markets and 
industry within which we operate.

The environment in which we operate is constantly evolving and 
can be affected by events that are outside of our control and 
which may impact on us both operationally and financially. New 
risks may emerge, the potential impact of known risks, including 
how quickly they escalate, and/or our assessment of these risks 
may need to change.

SEVERE

Analysing our identified risks

STRATEGIC RISKS 

1

   Organic growth: innovation  
and competition

2    Inorganic growth – acquisitions

OPERATIONAL RISKS 

3   Product safety

4   Supply disruption

5   Impact of tackling climate change

T
C
A
P
M

I

6   Business systems

7   Cyber-security

8   People

9   Supply chain management

COMPLIANCE RISKS 

10   Product regulations

11   Legal and compliance

OTHER RISKS 

12   Macro-economic 

13    Pandemics

14    Geopolitical and other 
worldwide events

RISK MOVEMENT

No Change

Movement

  New

2

1

4

10

7

11

12

13

9

14

6

8

5

3

For more information visit  
alliancepharmaceuticals.com

  The links between our principal risks and uncertainties and  
our strategy are set out in the table on pages 49 to 56

UNLIKELY

POSSIBLE

LIKELIHOOD

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022 
 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

48

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S   C O N T I N U E D

The Board, with the support of the Audit and Risk Committee, 
monitors and reviews risks in relation to those risks that could 
or are impacting the Group’s performance, its operations, and 
its stakeholders. The consideration of risks is inherent within the 
decision-making, and throughout the year the Board members 
have challenged management on key issues faced by the business.

 ›

 ›

 ›

 ›

The Board continues to monitor, and assess the likelihood 
of any further impact on the Group from the demand for 
Kelo-Cote™ in the China B2B market, which was recovering 
more slowly than the Company or its distribution partners 
had anticipated in 2022, impacting stockholdings and sales 
orders – the effects of which were communicated to the 
market on 23 November 2022.
The Nomination Committee accelerated its succession 
planning review for Executives and Senior Management 
– this work is ongoing and led to the appointment of Jeyan 
Heper as a new Chief Operating Officer. The Board was 
further enhanced by the appointment of Martin Sutherland, 
as a new independent Non-executive Director, who along 
with Jeyan has strengthened the Board.
The pressure of increases on costs of goods being felt by all 
businesses continues to be a key consideration for the Group 
– active engagement with our supply partners to mitigate 
any such increases, whilst also managing the sale side of the 
supply chain, has seen a reduction in the potential impacts, 
and the business remains focused on this key area.
The Board is mindful of the potential impact on the business 
of the Competition and Markets Authority’s (‘CMA’) decision 
dated 3 February 2022, including the proposed fine of 
£7.9m. The Board continues to believe that the Company has 
a strong case and is appealing the UK CMA’s decision. The 
date of the hearing is set for 5 June 2023.

Impact of tackling climate change
When reporting our principal risks and uncertainties 
for 2021, we took the decision to recognise climate 
change as an emerging risk, on the basis that we 
didn’t believe that we had sufficient clarity at that 
time to be able to assess its likely impact – and the 
likelihood of that impact occurring. 

Having now completed the scenario analysis 
needed to report in line with the recommendations 
set out by the Task Force for Climate-related 
Financial Disclosures (TCFD,) we have taken the 
decision to categorise the 'Impact of tackling climate 
change' as its own principal risk and to fully embed 
the management and oversight of this risk within 
our established operational risk management 
framework. The ESG Committee feels the work 
needed by the Group to move towards tackling those 
parts of its operations which have a direct impact 
on climate change (emissions in the supply chain, 
plastic packaging, etc.) more accurately reflects the 
risks (increased costs, operational disruption etc.) 
associated with climate change for our business.

  See our report on TCFD on page 35

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

49

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Strategic risks

1.  Organic 
growth: 
innovation and 
competition

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

Risk that we are unable to achieve our strategic growth ambitions due to 
a failure to keep pace with changing consumer preferences or due to a 
failure to identify and exploit new geographic markets for our products.

The products we sell are subject to normal market forces, so demand 
may fall, or the price we can achieve may be reduced, as our products 
face new or increased competition in response to changing consumer 
preferences for products or sales channel.

As a significant portion of our international sales are made via distributors, we 
are also at risk from losing a distributor or failing to secure a suitable distributor 
in existing or new markets. The significant proportion of sales into China via the 
CBEC trading route (in particular the B2B channel) leaves the Group exposed 
to the sensitivities of that market and the impacts of a slower than expected 
recovery of that market post-lockdowns. Widening sales distribution channels 
to include digital online sales platforms means sales could be affected should 
third-party systems become temporarily unavailable. We also face the risk of 
some of our more popular consumer products being subject to counterfeiting, 
where others seek to take advantage of the reputation built up in our brands for 
their own commercial exploitation.

 ›

 ›

Loss of revenue, reduced profitability and reduced 
growth from failure to maintain our competitive 
positioning, or to increase or maintain market share. 
In particular, the risk to Kelo-Cote™ forecast sales 
(principally in China) due to slower than expected 
recovery of the B2B trading channels could result in 
loss of high margin sales

Loss of revenue, and potential damage to reputation 
from counterfeit product reaching the market, which 
may not have been subject to the same rigorous 
quality and safety testing as genuine products

 › Continued focus on Marketing Excellence, to ensure we 
stay attuned to changing consumer preferences, and to 
maximise the value of our marketing campaigns

 ›

Increasing focus on innovation and development activities

 › Maintaining close working relationships with our 

distributors

 › Ongoing monitoring and forecasting of sales, costs, profits, 

and cash flows

 › Head of Brand Protection, brand protection strategies, 

support from external experts

 › Depending on its severity, this could also potentially 
impact our share price, cash flow and covenant 
compliance

 ›

 ›

Product or claims innovation strategies, to pre-empt 
patent expiration

Sustaining investment in brand promotion

2.  Inorganic 
growth – 
acquisitions

Risk that we are unable to deliver additional growth in excess of our strategic 
growth ambitions due to (i) lack of affordable funding (both debt and equity) 
(ii) a lack of suitable acquisition opportunities, or (iii) a failure to effectively 
integrate assets and maximize their potential once acquired.

There can be no guarantee that the Group will be able to identify suitable 
targets to continue to boost its growth through acquisitions. The market for 
high-quality assets – whether brands or corporates – is highly competitive 
and the Group may find itself unable to compete if the pricing of targets proves 
prohibitive. This would be further impacted by an inability to source affordable 
debt (or any debt depending on the Groups then prevailing leverage). A lack 
of sensible debt option would lead the Group to look to raise equity which 
itself may prove difficult or too expensive depending on the prevailing market 
sentiment and the impact this has on the prevailing share price.

As the Group looks to increase the size of acquisitions, the complexity and 
costs around both the acquisition itself and associated integration also 
increases.

 › Acquisitions fail to deliver expected benefits – due 

to overly optimistic forecasts, unidentified risks/poor 
evaluation of identified risks during due diligence, 
or as a result of failings in the integration process, 
resulting in integration taking longer/costing more 
than was originally anticipated

 › Distraction cost to the business from acquisition 

evaluation activities

 › Maintaining an active presence and continuing to grow our 
reputation in the M&A market, to ensure a good pipeline 
of opportunities

 › Ongoing refinements to our acquisition evaluation process

 ›

 ›

Experience gained from having completed multiple deals

Engage experienced legal, regulatory and financial 
experts to assist with the due diligence process

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

50

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Operational risks

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

3.  Product safety

Risk of an adverse reaction to one of our products constituting a safety 
risk for consumers.

 ›

The Group produces and sells a wide range of medicines, medical 
devices, food supplements and cosmetics. There are inherent risks that 
some of these products could cause adverse reactions.

Products have to be withdrawn from sale and we may 
have legal liability to those injured by the product, 
potentially damaging our reputation, and compromising 
our future performance. In an extreme scenario, this 
could impact our liquidity position or even solvency

 › Adverse event reporting and signal management for all 

medicine products – generally, the Group’s products are well 
tolerated, and many have been in existence for decades

 › Maintenance of necessary regulatory approvals for all products 

in the markets we trade in

4.  Supply 

disruption

Disruption to the continuity of supply as a result of our inability to 
procure critical ingredients, due for example to geopolitical events, 
logistics failures, or reliance on a single site of manufacture.

 › Maintenance of public and products liability insurance to 

provide an appropriate level of protection for the Company

 › Manufacturing, sourcing, or distribution issues, 

 › Maintaining close working relationships with our key suppliers, 

including an inability to increase production volumes 
to meet demand, impinges on our potential sales and 
has the potential to compromise our future performance 
and, in an extreme scenario, cash generation

 ›

 ›

 ›

to ensure we have early visibility of any potential issues

Ensuring we maintain adequate stocks of critical ingredients and 
of finished goods, to enable us to cushion the impacts of any 
disruption in the supply chain

Forward booking transportation, to minimise the impacts of 
any disruption to logistics provision – for example due to 
geopolitical and economic events

Putting in place dual sourcing arrangements for key products, to 
mitigate against manufacturer failure/inability to supply to meet 
sales demand

 › Where possible, and cost-effective, the potential financial 
impact of supply chain disruption is mitigated by insurance

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

51

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Operational risks continued

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Risk description and relevance

Potential impacts

Key mitigating activities

5.  Impact of 
tackling 
climate change

Risk to the longer-term viability of the business due to the impacts 
of all the changes to be made by the business to its operations in 
order to tackle the effects of climate change.

In addition, to the operational impacts of tackling the wider 
impact our business has on the climate, the Group also faces 
challenges from the direct physical impacts of climate change 
itself, e.g. the severity and frequency of adverse weather events 
and rising sea levels, and indirect impacts, such as higher energy 
costs, infrastructure funding, all of which are likely to become 
increasingly prevalent as we implement our plans to tackle  
the impact of climate change by transitioning to a  
low-carbon economy.

As detailed on page 36 of our TCFD disclosures potential 
impacts during the transition phase include:

Increased cost of energy and materials, in particular the 
increases which would come from ensuring more sustainable 
packaging for our products as we seek to transition 
away from plastics where possible. The increased costs 
of production and transportation associated with a more 
environmentally friendly supply chain, including the possible 
need to engage a more expensive group of selective 
manufacturers who meet the needs of our own  
ESG demands.

 › Changing consumer preferences and increased sensitivity 
to ESG with consumers potentially substituting existing 

 ›

 ›

products with lower emissions alternatives

Reputation damage due to a failure to respond to 

increased stakeholder concerns

The identified physical risks (see page 37) all have the 
potential to cause disruption to our business activities 
and supply chains in the longer term, depending on the 
warming pathway we find ourselves on.

 ›

 ›

Increased business focus on environmental strategy and 
associated risks

Engagement of third party expert support and wider 
engagement with competitors/peers to ensure we are able to 
utilise any improvements which are made in the wider market 
around issues such as packaging

 › Creation of TCFD roadmap and emissions reduction targets

Trend

NEW

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

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Financial Statements

Additional Information

52

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Operational risks continued

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

6.  Business 
systems

Failure to maintain and develop business systems and technology 
which adequately supports business processes, organisational 
infrastructure, and strategic growth ambitions, and enables us to 
manage any business continuity risk from unforeseen events.

The business is highly dependent on multiple IT systems – and 
systems failure as a result of a business continuity event could have 
a significant impact on the business’s ability to continue to operate 
effectively.

 ›

Loss of income or late market reporting as a result of 
a business continuity event causing loss of access to 
key resources, systems, and/or data. This could also 
potentially result in compliance failure, loss of control 
and an inability to trade

 ›

 ›

Improved change control/change management processes to 
better protect the integrity of our master data

IT Steering Group in place to maintain oversight of core 
systems and lead on changes required as a result of systems 
development or regulatory changes

 › Quality of data degrades as a result of not effectively 

managing data shared across multiple systems, leading 
to poor decision-making and increased transactional 
errors

 ›

Business continuity plans in place and under regular review

7.  Cyber security

Risk that the integrity, confidentiality and availability of our data  
and third-party information which we hold is compromised through 
cyber-attacks.

We hold significant amounts of confidential data relating to our 
products, our commercial activities, our financial transactions and all 
other aspects of our business operations in electronic format, making it 
susceptible to being compromised through cyber-attacks.

 ›

 ›

 ›

Reputational impact if we suffered a major loss of 
personal data as a result of a successful cyber-attack

Financial loss, data loss, or reputational damage 
due to fraud perpetrated through a successful social 
engineering attack

Financial transactions being rerouted fraudulently 
because sensitive transactional data is given away

We also hold confidential data on our customers and employees, 
some of which is collected via our transaction processes, and so 
includes their financial information in addition to other personal 
data, which is similarly at risk of loss, corruption, or unauthorised 
dissemination as a result of a successful cyber-attack.

 › Data destruction or ransom as a result of a malicious link 

being clicked

 › Use of anti-virus software, firewalls, and network segmentation

 ›

 ›

Ensuring all business software remains up to date, to provide 
additional in-built security

Implementation/review of incident management, business 
continuity and IT disaster recovery plans

 › Maintenance of appropriate physical and cyber security 
measures to prevent unauthorised access to information

 ›

 ›

Provision of training and alerts to staff to ensure that they are 
aware of known risks

Engagement of third parties to review and recommend ongoing 
improvements to enhance IT security and resilience

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

53

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Operational risks continued

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

8.  People

Failure to attract and retain sufficient high-quality people to deliver the 
business’s strategic growth ambitions.

By virtue of its business model, Alliance has a high level of reliance 
on the skills and knowledge of its employees, many of whom have 
considerable sector experience or other specialist expertise, making 
them attractive to competitors and not always easy to replace.

As the business continues to scale and to expand its geographic 
presence, our requirements for high-calibre people continues  
to increase.

9.  Supply chain 
management

The increasing globalisation of our supplier base as a result of recent 
acquisitions has served to increase our exposure to risks around 
Environmental, H&S, Business Ethics, Supply Chain Security and 
Climate and increases the risk of failing to maintain sufficient oversight 
of our end-to-end supply operations associated with these areas.

This is potentially a significant risk for Alliance, as our outsourced 
supply model has historically afforded only limited visibility of our 
end-to-end supply chain.

 ›

 ›

 ›

 ›

The loss of key employees could potentially weaken 
the Group’s operational/management capabilities, 
potentially impeding its ability  
to grow

 › Maintaining competitive incentive and reward structures, 

which remain attractive to existing employees and enable us to 
continue to attract high-quality applicants for  
new roles

Loss of continuity/loss of knowledge as a result 
of employee replacement, leading to operational 
inefficiencies

 › Clearly defined roles and responsibilities supported by 

documented systems and procedures to provide a level of 
continuity in the event an employee leaves the Group

Potential lack of required skills and expertise to support 
the continued growth of the business,  
its systems, procedures, and processes

 › Maintaining relationships with a number of international and 
local recruitment agencies to ensure we are able to find and 
recruit good quality employees

Potential reputational damage, loss of product supply 
and loss of revenues from failure to maintain sufficient 
oversight of our end-to-end supply operations

 › Maintaining a balance between permanent and contract heads 

to increase flexibility, particularly for project-based work

 › Our Know Your Supplier (‘KYS’) programme, which provides 
us with visibility of potential ‘red flags’ in our supply chain, 
enabling us to align compliance and escalation processes to 
facilitate timely remediation of issues

 ›

 ›

Project to review contract manufacturers is underway

The publication of our Partner Code of Conduct, setting out our 
expectations of our Partners from a business ethics perspective

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

54

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

Compliance risks

10.  Product 

regulations

Risk of non-compliance with product classification regulations and 
registration requirements, including relevant internal/external quality 
regulations and requirements, across all territories in which our 
products are manufactured and/or sold.

 ›

Product regulations are continually being updated, new requirements 
introduced (e.g. Medical Device Regulations), or product 
classifications changed.

In a number of territories our product registrations are maintained 
by local distributors in order to comply with local regulatory 
requirements, creating an added layer of complexity.

11.  Legal and 

compliance 
management

Risk of non-compliance with relevant laws and regulations in all 
countries in which we operate, including anti-corruption laws, data 
privacy laws, competition laws, accounting, taxation and listing 
regulations.

As the scope and scale of our business operations increases, we 
face an increasingly complex compliance burden. The level of legal 
and regulatory requirements to which we are subject continues to 
increase, and also the penalties for non-compliance, so it is vital 
that we are able to effectively manage all the various aspects of our 
compliance risk.

As we enter new territories and overseas markets, we become 
exposed to increased bribery, anti-slavery, and corruption risks. 
Likewise, as the Group expands its operations, the VAT and general 
tax environment in which it operates becomes more complex and the 
risk of incorrectly reporting and paying relevant taxes increases.

Some of our products may not gain regulatory approval 
or could face the risk of having their regulatory status 
challenged or adversely altered. This could affect the 
Group’s ability to launch new products or maintain sales 
of its current products in current jurisdictions or pursue 
further geographic expansion

 › Allocation of sufficiently experienced internal resource to 

support the regulatory approval of products, including any 
extensions to other markets

 › Maintenance of regular discussions with local regulatory 
advisers to monitor any products that may be subject 
to challenge

 › Non-compliance with product classification 

regulations/registration requirements may result in 
product having to be withdrawn from the market, with a 
consequential loss of sales

 ›

 ›

If compliance issues cannot be remediated, this could 
lead to cessation of product supply, or limitation of 
market opportunities

The Group has ongoing regulatory requirements 
(pharmacovigilance, etc.) which could, if not adhered 
to, lead to substantial fines and impact on the Group’s 
ability to sell certain products. Likewise, we may incur 
penalties for non-compliance as a result of adverse 
findings from regulatory inspections, which may 
potentially impact on the sales of our products, damage 
our brands and our reputation

 ›

Bribery, anti-slavery, and corruption all carry their own 
penalties, and reputational damage

 › A failure to abide by data protection rules or incur a 

breach of data security could also pose a financial and 
reputational risk to the Group

 ›

 ›

Breaches of VAT and taxation rules also carry a risk of 
interest and penalties becoming payable

Infringement Decision by the CMA relating to alleged 
anti-competitive agreement would, in the event that the 
Company’s appeal is not successful, lead to a fine of up 
to £7.9m

 › Continuing oversight of corporate compliance by in-house 

Company Secretarial function

 ›

 ›

Training for all employees on anti-bribery, anti-money 
laundering, competition law, market abuse, modern slavery, 
sanctions, tax evasion and GDPR

Engagement of third-party experts in our overseas territories to 
help us ensure compliance with local rules and regulations

 › Wide-ranging induction process for new starters to ensure they 
understand their individual, and the Group’s, obligations in 
relation to matters such as adverse event reporting

 ›

The filing of the notice of appeal against the CMA’s infringement 
decision and ongoing work with expert legal team to ensure that 
the Company’s appeal is as robust and effective as possible to 
give the Company the greatest chance of succeeding

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

55

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Financial risks

12.  Macro-

economic

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

Movements in FX rates adversely impact financial performance. 
The Group earns a proportion of its revenues and profits in 
currencies other than Sterling (principally Euros, US Dollars and 
Hong Kong Dollars), but accounts for the business in Sterling. The 
reporting of revenues and profits is therefore subject to volatility 
due to changes in exchange rates

Inflationary increases means that the business must ensure it 
adjusts its financial and commercial strategies either in the UK  
or overseas. 

Income generation could be impacted by operational and other 
risks, thereby increasing the Group's leverage.

 › Adverse movements in Sterling exchange rates vs Euro, 
US Dollar, Hong Kong Dollar and other currencies 
increase the costs of raw material and other overheads 
including wages and is often linked to supply chain 
disruption as markets adapt. 

 ›

 ›

 › Higher prices for goods will decrease consumer 

purchasing of non-essential products. 

 ›

Increased leverage would impact ability of the Group's 
ability to implement its desired capital allocation 
strategy, which could in turn stifle the growth potential.

The Group’s funding structure, with borrowings denominated 
in Sterling, Euros and US Dollars, provides a natural hedge to 
some of these exposures

The Group has a risk management policy to hedge up to 75% 
of its estimated future foreign currency EBITDA exposure for up 
to 18 months at any given point in time. The Group uses forward 
foreign exchange contracts to implement this policy, which are 
generally designated as cash flow hedges

 ›

Review pricing strategies across the portfolio and look to 
increase flexibility with supply chain

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

56

P R I N C I P A L   R I S K S   A N D   U N C E R T A I N T I E S 
C O N T I N U E D

Links to strategy:

Brand Growth

Commercial execution

Strategic supply partnerships

Agile organisation

Risk trends:

Risk has increased versus last year

Risk has reduced versus last year

Risk has not changed materially since last year

Other risks

13.  Pandemics

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

In common with most other businesses, we will always be at 
risk from extreme and unexpected global events affecting our 
ability to operate. This could be an event that affects our people, 
our operational sites, our IT systems, or any other aspect of 
our business operations. This was the case with the COVID-19 
pandemic which surfaced in 2020, the aftermath effects of which 
continues to impact our trading environment today, particularly  
in China.

 ›

 ›

Reduction in revenues/profitability and/or failure to 
achieve expected growth due to reductions in demand 
or potential supply issues. Any significant impact on 
the Group’s revenues and profitability could potentially 
affect the Group’s ability to comply with its borrowing 
covenants

Pressure on sourcing and supply chain could lead to (i) 
an increase in the cost of transportation, raw materials 
and goods in general, or (ii) a reduction in availability 
of certain materials, both of which could in turn impact 
profitability

 › Work toward less value concentration of our business in any one 
jurisdiction or market to try and mitigate inability to make sales 
in affected areas.

 › Move towards more on-line sales for those of our products 

which are permitted to be sold on-line, with a drive to increase 
share on those on-line channel, to help mitigate any loss of sales 
for physical markets are shut down.

14.  Geopolitical 

and 
worldwide 
events

Last year, we saw how the escalation of geopolitical events in 
Europe had the potential to cause supply chain disruption within 
the business and subject us to increased economic uncertainty. 
Any further escalation of the current conflicts, or any new conflicts 
in or connected to our major markets could have a significant 
impact on sales or manufacturing.

Inflationary pressures globally are increasing costs of goods.

 › Disruption caused by military or political conflict/
tensions could cause our markets to be restricted 
or even close. This could lead to loss of sales and a 
potential inability to recover market share if/when those 
issues are resolved

 ›

Increased costs/reduced demand for goods due to 
weaker economic growth and higher inflation

 › General inflationary pressures being experienced by 
the wider business community will lead to increased 
pressure on workforce costs and rewards, which in turn 
could impact profitability

 ›

Increasing costs impact our profits and ability to remain 
competitive. This could also impact market share 

 ›

Regular review and updating of demand forecasts to 
understand and mitigate any potential adverse effects on 
revenues, supported by our recently improved S&OP processes

NEW

 › Maintenance of close working relationships with suppliers and 

distributors; ongoing monitoring for any signs of distress

 › Keeping abreast of global events and economic conditions in 

the territories in which we operate to ensure risks are monitored 
accordingly.

Strategic Report
 Chief Executive’s Review 

Market Overview 

 Our Strategy 

Spotlight on…

Marketing excellence 

Innovation and development 

ScarAway™ and Kelo-Cote™  
US acquisition 

Culture, people and values 

Key Performance Indicators 

Sustainability 

Spotlight on…

06

09

12

18

20

22

24

27

29

Managing our packaging estate 

31

Developing our response to  
climate change  

TCFD 

Stakeholder Engagement 

Financial Review 

 Principal Risks and Uncertainties 

33

35

40

42

47

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

57

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

Alliance Pharma plc Annual Report and Accounts 2022

Governance

“ We continue to ensure that 
our corporate governance 
processes remain robust, 
challenging and appropriate.”

David Cook, Chair

For more information visit  
alliancepharmaceuticals.com

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Financial Statements

Additional Information

58

C H A I R ’ S   I N T R O D U C T I O N

“ Our governance framework helps us 
set priorities, establish accountabilities 
and manage risks effectively.”

Dear shareholders and colleagues, 
In my last year as Chair and on behalf of the Board, I am pleased to introduce the Governance 
Report for the year ended 31 December 2022. The following sections provide readers with an 
overview of the Group’s governance arrangements. 

As a company admitted to AIM, our governance is underpinned by the Quoted Companies 
Alliance (‘QCA’) Corporate Governance Code 2018 (‘the QCA Code’). During the year, we 
have complied with the principles of the QCA Code and details of how we have done so can be 
found in the governance section of the Company’s website. The Board continues to ensure that our 
corporate governance processes remain robust, challenging and appropriate providing strong 
foundations to underpin our assessment of risks to our strategy and the delivery of that strategy for 
the long-term sustainability of the business.

During the year we took the opportunity to review and reset our strategy and we have redefined 
our vision and purpose, which you can read more about on pages 12 to 17. We have aligned this 
with our governance framework to ensure it is supportive of the strategy and the decisions we as a 
Board and as Directors must make. This year has not been without its challenges, as the business 
has continued to navigate certain externalities resulting from changes in the macro-economic, 
political and residual post-pandemic environments. Some of these challenges are explained in the 
section on Protecting the Business on page 47. The good work of the Committees also ensures there 
is appropriate focus with sensible, pragmatic outcomes. You can read more about their work in the 
reports that follow.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

59

C H A I R ’ S   I N T R O D U C T I O N   C O N T I N U E D

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

Developing our strategic 
partnerships to ensure the 
sustainable organic growth of 
the business

Steady progress against our 
sustainability objectives with 
continued oversight from the 
ESG Committee

Succession planning and 
incentive structures to ensure 
effective, motivated leadership 
to support the future direction of 
the Company 

Challenging financial 
performance and resilience 
across the business to ensure 
sustainable foundations  
for growth

For more information visit  
alliancepharmaceuticals.com

At the same time, we announced that 
the Board had agreed the appointment 
of Richard Jones as Senior Independent 
Director whose role will provide further 
support to Board members and shareholders. 

On 18 May 2022, we announced the 
successful appointment of Jo LeCouilliard as  
my successor as Chair. I wish Jo all the very  
best in her new role.

2023 ANNUAL GENERAL MEETING
This year’s AGM will be held at 9.00am on  
25 May 2023. Further details can be found in 
the Notice of AGM accompanying this Report. 
As previously announced, I will be stepping 
down as Chair and Director of the Company at 
the end of the 2023 AGM as I hand over the 
role to Jo LeCouilliard. 

The Board and I would like to thank all 
shareholders and colleagues for their continued 
support, and we look forward to continuing 
with our good work during 2023.

David Cook
Chair
20 March 2023

CHANGE OF AUDITOR
This year we were pleased to welcome Deloitte 
LLP as the Company’s new auditor following 
KPMG LLP’s resignation at the beginning of 
August 2022. Shareholders will see that their 
reappointment is proposed at this year’s Annual 
General Meeting (‘AGM’).

BOARD APPOINTMENTS
You can read about the Directors’ skills and 
experience on pages 61 and 62. 

As previously announced, we were  
delighted that Jeyan Heper joined as  
Chief Operating Officer, and also joined 
the Board, on 1 February 2023. Jeyan has 
a strong track record of strategic leadership 
in the international consumer health market, 
overseeing a number of global programmes 
and driving growth in flagship brands. He 
has responsibility for the Group’s operational 
capabilities, identifying growth opportunities, 
and further driving the Company’s strategy to 
expand its consumer health presence. 

To further support the delivery of our 
strategy we also welcome Non-executive 
Director Martin Sutherland who joined us on 
1 February 2023. Martin has a proven track 
record of delivering growth through new 
product innovation, market diversification 
and international expansion. We believe 
that Martin’s experience will bring a new 
perspective to complement the strong 
consumer healthcare knowledge already 
present on the Board.

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Strategic Report

Governance

Financial Statements

Additional Information

60

O U R   G O V E R N A N C E   S T R U C T U R E

THE BOARD
Responsible for the Group’s vision, business model, risk and strategy. Together, the Directors are responsible  
for providing effective leadership to promote the long-term success of the Company.

 See our Board of Directors on pages 61 to 62

CHIEF EXECUTIVE OFFICER
Responsible for the day-to-day running of the business 
and the implementation of the Group’s strategy.

BOARD CHAIR
Leadership of the Board and facilitating the effective 
contribution of all members to meetings.

BOARD COMMITTEES
Four Committees operate under delegated powers 
and with clear terms of reference.

SENIOR LEADERSHIP TEAM
Support CEO and have management responsibility for the  
business operations and its support functions.

NOMINATION COMMITTEE
Reviews the leadership needs of the 
organisation and monitors succession planning 
for both Board and senior executive roles. 
Responsible for the selection process and 
nomination of all Directors to the Board, and 
reviews the structure, size, and composition of 
the Board

AUDIT AND RISK COMMITTEE
Monitors and reviews the financial results and 
other reporting and oversees the effectiveness 
of risk management and systems of internal 
control. Provide confidence to shareholders on 
the integrity of reported financial results and 
challenge to the external auditors and  
senior management.

REMUNERATION COMMITTEE
Ensures there is a formal process for reviewing 
salaries, benefits, and other terms of service to 
determine appropriate levels of remuneration 
for the Executive Directors and other  
senior executives.

ESG COMMITTEE
Reviews the overarching ESG vision for the 
Company and ensure that the priorities are 
anchored to become an integral part of the 
overall strategy.

 Read more on pages 69 to 71

 Read more on pages 72 to 76

 Read more on pages 77 to 85

 Read more on pages 86 to 87

Committee Chair: 
Jo LeCouilliard

Members: 
4

Meetings:
8

Committee Chair: 
Richard Jones

Members: 
3

Meetings:
8

Committee Chair: 
Jo LeCouilliard

Members: 
3

Meetings:
7

Committee Chair: 
David Cook

Members: 
6

Meetings:
2

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

61

B O A R D   O F   D I R E C T O R S

COMMITTEE 
MEMBERSHIP KEY

Audit and Risk Committee
View report on page 72 

Nomination Committee
View report on page 69

Remuneration Committee
View report on page 77

ESG Committee
View report on page 86

C

Committee Chair

David Cook
Independent Non-executive Chair

Peter Butterfield
Chief Executive Officer

Andrew Franklin
Chief Financial Officer

Jeyan Heper
Chief Operating Officer

COMMITTEE MEMBERSHIP AS AT 31 DECEMBER 2022

  C
DATE JOINED

David joined the Board of Alliance as a Non-executive 
Director in 2014 and was appointed Chair of the Board on 
1 March 2018.

Peter was previously the Company’s Deputy Chief 
Executive Officer and was appointed to his present office 
as Chief Executive Officer on 1 May 2018 having joined 
Alliance in 2010 as an Executive Director.

Andrew joined Alliance in September 2015 from 
Panasonic Europe Ltd, where he was General Manager, 
European Tax and Accounting.

QUALIFICATIONS

David graduated in Chemistry at the University of Oxford 
and is a Chartered Accountant.

Peter holds an honours degree in Pharmacology from the 
University of Edinburgh. 

Andrew holds an honours degree in Civil Engineering from 
the University of Wales, Cardiff.

EXPERIENCE

He is currently Chief Financial Officer and an Executive 
Director of Ellipses Pharma, an international cancer 
drug development company, and was previously Chief 
Financial Officer and Chief Business Officer of Biotie 
Therapies Corp, a drug development company quoted in 
Helsinki and on NASDAQ. He has previously held senior 
financial positions with Jazz Pharmaceuticals International, 
EUSA Pharma and Zeneus Pharma.

David has extensive experience of financial and general 
business management (including the implementation 
of buy and build strategies) in the life sciences sector, 
of financing those businesses and managing investor 
relations across a number of stock markets globally.

Peter has over 20 years’ experience in the life sciences 
sector and strong leadership experience gained in a 
variety of contexts. Peter joined the Board of Alliance in 
2010 with the acquisition of Cambridge Laboratories 
where he spent five years, latterly as UK Commercial 
Director. Prior to joining Cambridge Laboratories, 
Peter spent six years at GlaxoSmithKline in a variety of 
marketing and sales roles.

From 2010 to 2012 Andrew was Finance Director and 
Company Secretary of Genzyme Therapeutics Ltd, the UK 
and Ireland subsidiary of Genzyme Corporation. Prior to 
that, he gained 12 years’ pharmaceutical experience with 
Wyeth in a variety of senior financial positions.

Andrew is a Fellow of the Institute of Chartered 
Accountants in England and Wales with extensive 
experience of financial management of international 
businesses, including significant prior experience in life 
sciences companies. 

Jeyan joined Alliance as Chief Operating Officer and 
Board member on 1 February 2023. He has more than  
25 years of diverse experience with a strong track record 
of strategic leadership in the international consumer health 
market, overseeing a number of global programmes and 
driving growth in flagship brands. 

Jeyan graduated from the Bosphorus University in Istanbul 
with a Bachelor of Arts degree in Political Science and 
International Relations.

Jeyan has held senior executive roles at Proctor & Gamble 
and Danone Group. In addition, Jeyan was President 
and General Manager of Ansell’s sexual wellness global 
business before it was spun-out to become Lifestyles 
Healthcare, a private equity/pharma-owned company 
where Jeyan became CEO. 

During his tenure as CEO at Lifestyles Healthcare, 
Jeyan delivered significant growth through market and 
category expansion, building a strong e-commerce 
platform in China and the US, and improving operational 
effectiveness. Most recently, Jeyan worked as Head of 
Global Transformation at British American Tobacco (BAT) 
and held a Non-Executive Director seat on the Board of 
NASDAQ-listed Organigram Inc.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

62

B O A R D   O F   D I R E C T O R S  C O N T I N U E D

COMMITTEE 
MEMBERSHIP KEY

Audit and Risk Committee
View report on page 72 

Nomination Committee
View report on page 69

Remuneration Committee
View report on page 77

ESG Committee
View report on page 86

C

Committee Chair

Jo LeCouilliard
Independent Non-executive Director

Richard Jones
Senior Independent Non-executive 
Director

Kristof Neirynck
Independent Non-executive Director

Martin Sutherland
Independent Non-executive Director 

COMMITTEE MEMBERSHIP AS AT 31 DECEMBER 2022

  C   C  
DATE JOINED

C  

Jo joined Alliance as a Non-executive Director on 
1 January 2019.

Richard joined Alliance as a Non-executive Director on 
1 January 2019.

Kristof joined Alliance as an Independent Non-executive 
Director on 1 December 2021.

Martin joined Alliance as an independent Non-executive 
Director on 1 February 2023. 

QUALIFICATIONS

Jo graduated in Natural Sciences from Cambridge 
University and is a Chartered Accountant.

Richard has a degree in Engineering from Newcastle 
University and is a Chartered Accountant.

He graduated as a Master of Science in Electronic 
Engineering from the University of Ghent, Belgium.

EXPERIENCE

Jo has 25 years’ healthcare management experience 
gained in Europe, the US and Asia. Much of her career 
has been in pharmaceuticals at GlaxoSmithKline where, 
amongst other roles, she headed the US vaccines business 
and Asia Pacific Pharmaceuticals business and led a 
programme to modernise the commercial model. She was 
previously Chief Operating Officer at the BMI group of 
private hospitals in the UK. She was Non-executive Director 
at Frimley Park NHS Foundation Trust in the UK, Duke NUS 
Medical School in Singapore and Cello Health plc.

She is currently a Non-executive Director at UK listed 
companies Indivior plc and Niox Group plc (formally 
Circassia Group plc). She is also on the Board of Recordati 
S.p.A, a company listed on the Milan Stock Exchange.

Richard was appointed as Chief Financial Officer at UK 
main market listed Medica Group PLC, an international 
provider of high-quality telemedicine services. Prior to this, 
Richard gained extensive experience in the healthcare 
sector in his roles at UK AIM listed companies Mereo 
BioPharma Group PLC and Shield Therapeutics PLC. At 
Mereo, he had a leading role In the merger with US listed 
OncoMed Pharmaceuticals, Inc and Mereo’s dual listing 
on Nasdaq In 2019. 

At Shield he had a leading role establishing the finance 
operations and guiding Shield through its 2016 IPO. 

His prior career in investment banking included senior 
positions at Investec and Brewin Dolphin Securities, 
where he advised healthcare clients on a wide range of 
transactions including IPOs, M&A and fundraisings.

Kristof is Global Chief Marketing Officer and Managing 
Director Western Europe at Avon Cosmetics and brings 20 
years of experience in General Management, Marketing, 
Digital Transformation, and Innovation, having carried 
out roles in Fast Moving Consumer Goods/Consumer 
Packaged Goods, Luxury and Retail sectors across multiple 
geographies. He is well versed in operating across an 
omnichannel model, combining bricks and mortar retail, 
e-commerce and direct-to-consumer experience.

Kristof joined Walgreens Boots Alliance in 2015 and 
in 2017 became their Chief Marketing Officer for their 
Global Brands division where he had responsibility for 
a $4bn sales portfolio of more than 20 of their owned 
brands in Beauty and Consumer Healthcare. Prior to this, 
Kristof held leadership roles at P&G’s Prestige, Laundry 
and Feminine Care global divisions, having started his 
career in 2002 at Procter & Gamble in Belgium before 
moving to Procter & Gamble International in Switzerland 
in 2004.

Martin graduated from Oxford University with a Master of 
Arts degree in Physics and The University College of London 
with a Master of Science degree in Remote Sensing.

Martin is a senior executive with more than 30 years of 
global business experience. He is currently a NED at 
FTSE listed Forterra plc, a leading UK manufacturer of 
essential clay and concrete building products, sitting 
on their Nomination, Remuneration, Audit and Risk and 
Sustainability Committees. Martin is also a NED on the 
Board of Reliance Cyber, a privately held specialist  
cyber security business where up until January 2023 he  
was CEO. 

Martin was CEO of De La Rue plc from 2014 to 2019 
and previously held a variety of roles at Detica plc, 
becoming Managing Director in 2008 on its acquisition 
by BAE Systems plc delivery. He brings experience in 
delivering growth through new product innovation, market 
diversification and international expansion.

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Financial Statements

Additional Information

63

G O V E R N A N C E

KEY ACTIVITIES OF THE BOARD AND ITS COMMITTEES
Throughout the year the Board received regular updates on, and considered, strategy, the commercial and financial performance of the business, scientific affairs and operations, people and infrastructure 
and legal and governance. In addition to these standing items, other business considered by the Board and its Committees is set out below.

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug*

Sep

Oct

Nov

Dec

Strategic planning 
Strategy planning, review of Group strategy, presentations from business and functions

2023 Budget 
Presentations and budget approval

Corporate development 
Review of historical acquisitions

Business reviews 
Mainland Europe, Asia Pacific, US, various product and brand reviews, brand protection, Great Place to Work,  
Innovation and Development

Investor engagement and broker presentations 
Full and half-year results webcast presentations, analyst calls and investor road-shows, private client fund manager meetings, one-to-one 
calls and AGM, and presentations from brokers 

Company results, trading statements and dividends 
Annual Report and Accounts, dividend policy and declarations

Nomination Committee  
Board composition and Committee membership, Board and senior management succession planning, NED recruitment, terms of reference

Remuneration Committee 
Review of salary proposals 2022, Executive remuneration, 2022 corporate bonus awards, Review of incentive plans, 2022 Company 
share option awards, 2023 corporate bonus scheme, objectives and targets, terms of reference

Audit and Risk Committee  
Appointment of new auditor, key accounting estimates and judgements, significant accounting policies, annual audit process and fees, 
external auditor, internal audit, foreign currency and hedging

ESG Committee 
Sustainability framework and initiative, investor engagement, disclosure and accounting metrics, carbon action plan and environmental 
strategy, TCFD reporting and corporate website disclosures

X

X

X

X

X

X

X

X

X

X

X

X

Governance & Legal 
Includes the review of risk management framework, Board Effectiveness Review, Governance reporting, AGM Notice, litigation, Modern 
Slavery Statement, review of gender pay, Group compliance

X

X

* Although there is no scheduled meeting in August, a management pack is circulated.

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Governance

Financial Statements

Additional Information

64

G O V E R N A N C E   C O N T I N U E D

THE ROLE OF THE BOARD
The Board is responsible for the Group’s vision, business 
model and strategy. Together, the Directors are responsible for 
providing effective leadership to promote the long-term success 
of the Company.

Each year the Board holds a two-day strategy planning 
meeting at which the SLT and other senior employees present 
their proposals. From this session, the Group’s strategic plan 
and business model is agreed. The CEO is responsible for 
the implementation of the strategy which is communicated to 
all employees by the management team through breakfast 
briefings and online presentations. Further information on 
how the Company delivers the strategy to promote long-term 
growth can be found on pages 12 to 26.

There is a formal list of matters reserved for the Board, which may 
only be amended by the Board and is available on our website. 
The Board’s key responsibilities include:

 › maintaining the policy and decision-making process through 

 ›

 ›

which the strategy is implemented;
checking that necessary financial and human resources are 
in place to meet strategic aims;
providing entrepreneurial leadership within a framework of 
good governance and sound risk management;

 › monitoring performance against key financial and non-

financial indicators;
responsibility for risk management and systems of internal 
control; and
setting values and standards in corporate governance matters.

 ›

 ›

THE BOARD AND ITS COMMITTEES
The Board currently comprises eight Directors, being the 
Chair, four further independent Non-executive Directors and 
three Executive Directors. Following David Cook’s departure, 
there will be seven Directors comprising the Chair, three 
further independent Non-executive Directors and three 
Executive Directors.

The Chair
The Chair, David Cook, has primary responsibility for leading the 
Board and facilitating the effective contribution of all members to 
meetings. He maintains a strong focus on governance to ensure 
good practice is embedded in the business with good flows in 
communication and reporting. He has regular dialogue with the 
CEO to ensure the business and the management team receive 
the support from the Board necessary to progress the strategy. 
As announced on 18 May 2022 David steps down as Chair 
of the Company from the 2023 AGM and Jo LeCouilliard will 
become Chair of the Board.

The Chair also meets with the Non-executive Directors on their 
own at least once a year and further meets with them as part of 
the Board evaluation process. Shareholders have an opportunity 
to engage with the Chair and the Board at the Company’s AGM.

The Chief Executive Officer (‘CEO’)
The CEO, Peter Butterfield, is responsible for the day-to-day 
running of the business and implementation of the Group’s 
strategy. He is supported by the SLT, who have management 
responsibility for the business operations and support functions. 
Relevant matters are reported to the Board by the CEO and, as 
appropriate, the CFO and other members from the SLT.

Since the announcement on 23 November 2022 that Peter 
Butterfield was taking leave from the business, Andrew 
Franklin has been acting CEO and continues to do so as 
at the date of this Report. He has been carrying out these 
responsibilities in Peter’s absence. 

The Senior Independent Director (‘SID’)
On 1 February 2023, at the recommendation of the Nomination 
Committee, we announced the appointment of Richard Jones as 
SID. His role is to act as a sounding board and intermediary for 
the Chair and other Board members. His responsibilities include 
leading the performance evaluation of the Chair and attending 
meetings with shareholders and analysts to obtain a balanced 
understanding of any issues or concerns.

The Non-executive Directors
Non-executive Directors are required to commit the time 
necessary to fulfil their role to:

 ›

 ›

 ›

 ›
 ›

 ›

provide oversight and scrutiny of the performance of the 
Executive Directors;
constructively challenge to help develop and execute on the 
agreed strategy;
satisfy themselves as to the integrity of the financial reporting 
systems and the information they provide;
satisfy themselves as to the robustness of the internal controls;
ensure that the systems of risk management are robust and 
defensible; and
review corporate performance and the reporting of such 
performance to shareholders.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Governance

Financial Statements

Additional Information

65

G O V E R N A N C E   C O N T I N U E D

Independence on the Board is reviewed and confirmed 
annually by the Nomination Committee. Each of the Non-
executive Directors sits on at least three of the Committees 
ensuring that between them they have a role in determining 
the pay and benefits of the Executive Directors and in the 
planning of Board succession, including the appointment 
and, if necessary, removal of Executive Directors. They are 
appointed for an initial term of five years, subject to annual 
re-election by shareholders at the AGM. Their appointment 
term may be renewed by mutual agreement.

Meeting management 
The Company Secretary is secretary to the Board and the 
Board’s Committees. On behalf of the Chair, the Company 
Secretary is responsible for ensuring that all Board and 
Committee meetings are conducted properly and that the 
Directors are properly briefed on any item of business to be 
discussed. He has a direct line into the Chair on all matters 
relating to governance and is responsible for ensuring 
governance, legal and regulatory compliance is considered, 
recorded and implemented. 

Board attendance, support and meeting management
Meeting attendance
Directors are expected to attend all Board meetings. This includes 
a two-day strategy meeting in each year which is also attended 
by all senior executives of the Group to review progress in 
delivering the Group’s long-term strategic objectives. 

Member

David Cook

Peter Butterfield*

Andrew Franklin

Kristof Neirynck

Jo LeCouilliard**

Richard Jones**

Role

Chair

CEO

CFO

NED

NED

NED

Status

Attendance

Independent

–

–

Independent

Independent

Independent

14/14

12/14

14/14

14/14

13/14

13/14

* Peter Butterfield took leave from the business with effect from 23 November 2022.

**  Jo LeCouilliard and Richard Jones were recused from meetings in which they had an 

interest.

Procedures are in place for distributing meeting agendas 
and reports so that they are received in good time, with the 
appropriate information. Ahead of each Board meeting, the 
Directors each receive written reports updating on strategy, 
finance, including monthly management accounts, operations, 
commercial activities, business development, risk management, 
legal and regulatory, people and infrastructure and on investor 
relations. Meeting papers are distributed via an electronic 
Board portal.

The Directors may have access to independent professional 
advice, where needed, at the Group’s expense.

Board Committees 
The Board has delegated and empowered four Committees: a 
Remuneration Committee, a Nomination Committee, an Audit 
and Risk Committee and an ESG Committee. Each Committee 
has written terms of reference set by the Board, which are 
reviewed annually and are available on the Company’s website. 

The Board held 11 scheduled meetings, and three unscheduled 
meetings, during the year. Meetings follow a clear agenda, 
supported by written reports and presentations from both internal 
members of staff as well as external advisers and consultants. 

Membership of each Committee is determined by the Board on 
the recommendation of the Nomination Committee. Executive 
Directors are only permitted to be members of the ESG 
Committee.

Each Committee Chair reports to the Board on the activities 
considered and determined by the relevant Committee. A 
summary of the Committees’ responsibilities and their work 
during the year can be found in the reports from the Committees 
appearing later in this section.

Directors’ conflicts of interest
The Company has effective procedures in place to monitor and 
deal with conflicts of interest. Directors are required to notify 
the Company of any situation that could give rise to a conflict 
or potential conflict thereby compromising their independence 
and objectivity. Each member is required to disclose any such 
potential conflicts at the start of every meeting. The Board is fully 
aware of the other commitments and interests of its Directors, and 
changes to these commitments and interests are reported to and, 
where appropriate, agreed with the rest of the Board. Where 
any such conflict arises, the Board determines whether or not a 
Director can vote or be a party of the item under consideration 
in accordance with the Company’s Articles of Association. The 
Board is satisfied that potential conflicts have been effectively 
managed throughout the year.

Director induction, training, and development
The Company Secretary is responsible for ensuring that all newly 
appointed Directors receive a thorough formal tailored briefing 
and induction on joining the Board aimed at providing Directors 
with the information to become effective as soon as possible in 
their role. The induction has the aim of:

 ›

 ›

 ›

building an understanding of the Company’s business 
and markets;
building a link with the Company’s people and an 
understanding of the Company’s main relationships; and
ensuring an understanding of the Board’s governance 
framework and Board processes.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Governance

Financial Statements

Additional Information

66

G O V E R N A N C E   C O N T I N U E D

Each Director received one-to-one inductions with Board and 
SLT members and are provided with access to the Directors’ 
handbook. Both Jeyan Heper and Martin Sutherland received 
tailored inductions which included but wasn’t limited to:

 › meetings with each Board member and their roles and 
responsibilities on the Board and the Committees;

 › meetings with each SLT member to explain their areas of 

responsibility within the business; 
an explanation of the Company’s governance and 
compliance framework, including Board procedures;
an explanation of Directors’ responsibilities under the AIM 
Rules and other statutory and regulatory rules; and
pharmacovigilance and Good Distribution Practice inductions.

 ›

 ›

 ›

All the Directors are responsible for ensuring their skills and 
knowledge are kept up to date. This is done in varying ways 
but includes professional training, online training or attending 
seminars and webinars offered by advisers and consultancies. 
In addition, regular updates on corporate governance, legal or 
regulatory changes are also provided via reporting or through 
presentations to the Board.

BOARD RESPONSIBILITY FOR SUSTAINABILITY
The Board has overall responsibility for the Group’s sustainability 
strategy and programme which includes climate policy and 
action and TCFD reporting. In 2022 we continued to refine our 
approach to our sustainability framework. The ESG Committee 
is responsible for setting the Group’s overarching Sustainability 
Strategy, including climate change, and you can read more 
about the Committee’s work on pages 86 and 87.

CORPORATE CULTURE AND BUSINESS CONDUCT
Our culture is underpinned by a clear set of values, which help 
guide decision-making at all levels in the business.

The Board expects the business to foster relationships and 
operate high standards of business conduct. We recognise 
that investors are increasingly looking for socially responsible 
companies to invest in, employees are seeking employers with 
a strong ethics culture that aligns with their own moral code, 
and customers are conducting enhanced due diligence on their 
suppliers’ ethical and legal compliance controls. 

The Board reviews and approves the Group’s policies that have 
been implemented and communicated internally and externally 
in the Company’s core languages to those who are expected to 
adhere to them. For example, in addition to the codes of conduct, 
this includes policies on diversity and inclusion, the prevention of 
bribery and corruption, fair competition, conflicts of interest and 
anti-slavery. Further information about our policies can be found 
in Sustainability – Policies and Documents on our website.

STAKEHOLDER ENGAGEMENT
Engaging with the Company’s stakeholders is well embedded in 
the business as we continue to look after our relationships with 
shareholders, employees, customers, suppliers and consumers 
and the wider communities. The Board is made aware of and 
considers the needs and interests of these various stakeholders 
and any impact of the decisions it makes.

Visibility and awareness are further increased through 
senior management who have collective responsibility for 
communicating and engaging with specific stakeholder groups. 
This includes making sure that the business upholds its values and 
monitors behaviour for acceptability.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

67

G O V E R N A N C E   C O N T I N U E D

PROMOTING THE SUCCESS OF THE COMPANY – S.172
The powers and duties of the Directors are determined 
by legislation and the Company’s Articles of Association. 
Collectively, they have a duty to promote the success of Alliance 
for the benefit of its members over the long term. 

The Directors are aware and mindful of their duties and 
obligations under s.172 of the Companies Act 2006 (Section 
172). They are required to act in good faith and their discussions 
give due consideration to the impact of those decisions on the 
Group’s strategy, values, and the interests of the Company’s 
various stakeholders. Each Director is responsible for weighing 
up all the relevant factors and how these ultimately promote 
the long-term success of the Company for the benefit of its 
shareholders as a whole. To help them reach well informed 
decisions they are provided written reports, market reviews, 
guidance, and presentations and briefings from both internal 
members of staff and external advisers alongside which assists 
them when assessing any risks. 

Throughout this Annual Report there are various examples of how 
the actions and behaviours of the business affect the interests of 
its employees, customers, suppliers, the wider community and 
the environment but in this section we also demonstrate how the 
Directors have applied their duties under Section 172.

The likely consequences of  
any decision in the long term

The interests of the  
Company’s employees

The need to foster the Company’s business  
relationships with suppliers, customers, and others

The Board considers the long-term consequences on 
the business and its stakeholder group when setting 
and approving the strategy and the annual budget. 
For this purpose, the Directors consider the 
assessment of risks and opportunities and how these 
might benefit shareholders, and impact, for example, 
consumers, suppliers and employees. A long-term 
approach ensures the Directors take decisions that 
mean a more sustainable business. The strategy is 
explained on pages 12 to 17.

The Board considers the activities and welfare of the 
Company’s employees at its meetings and from time 
to time, employees are invited to attend Board and 
Committee meetings to present on key operational, 
financial, and strategic matters. There is regular 
dialogue between the SLT and all employees through 
Breakfast Briefings at which employees are briefed 
on matters such as the outcome of surveys, 
organisational changes, and other positive initiatives 
to support their health and wellbeing. This helps to 
ensure our employees remain engaged. They are 
also able to participate in the Company’s employee 
share option schemes to ensure they feel aligned with 
the Company’s plans for growth over the longer term. 
You can read more about our employee engagement 
on pages 24 to 26 and on page 40.

When the Board reviews the Company’s strategy, the 
annual budget and risks, due consideration business 
relationships to ensure that they support the long-term 
objectives. In addition, the Board reviews policies 
and codes of conduct that govern these relationships 
took into consideration of some elements for strategic 
report and sustainability sections i.e., on anti- bribery 
and corruption, human rights, as well as supply chain 
resilience. More on the Company’s engagement with 
its stakeholders can be found on pages 40 and 41.

The impact of the Company’s operations  
on the community and the environment

The desirability of the Company maintaining a 
reputation for high standards of business conduct

The need to act fairly as between  
members of the Company

The work of the ESG Committee helps the Directors 
consider their responsibilities in relation to the 
environment and wider communities. They receive 
updates on climate risk and the impact of the business 
on the environment. All employees are also 
encouraged to participate in the process to drive 
positive change. When the Board is discussing 
consumer products, it discusses the benefits and 
timings of transitioning towards sustainable 
packaging and considers solutions that help drive the 
sustainability agenda. The Board’s commitment in this 
area is demonstrated by approval of the Alliance 
Environment Strategy and Carbon Action Plan. You 
can read more on the Company’s sustainability 
objectives on pages 29 to 39.

The Board ensures that the right culture is embedded 
throughout the business and is in part attributable to 
the Company’s values, attitudes and behaviours 
when conducting its business and engaging with 
stakeholders. Maintaining high standards promotes 
the reputation of the Company, which is clearly 
communicated via the Partner Code of Conduct – 
available on the Company’s website. 

Shareholders are kept informed of Company news 
via stock exchange announcements, website and 
hard copy communications. With the support of 
Investor Relations all shareholders receive 
information by their chosen method. In addition, the 
Company sets up investor roadshows to meet with 
shareholders and discuss any concerns they have. 
More recently, the Board took the decision to appoint 
a Senior Independent Director to assist the Chair with 
shareholder engagement. All shareholders are also 
encouraged to attend the Company’s AGM each 
year, where they can ask questions freely.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

68

G O V E R N A N C E   C O N T I N U E D

ENGAGEMENT WITH SHAREHOLDERS
The Board and its Committees recognise that to meet their 
responsibilities to shareholders and other stakeholders, 
it is important to ensure effective engagement with, and 
encourage participation from, these parties. 

When engaging with shareholders, the Directors are 
supported by the Head of IR and Corporate Communications 
(Head of IR).

Throughout the year, the CEO, CFO, Chair, Non-executive 
Directors and Head of IR met with potential and existing 
investors, and they fed back to the Board the key summary points 
from their meetings. In addition to these meetings, there were 115 
scheduled meetings held as part of the Company’s investor road-
shows for the annual 2021 and half-year 2022 results.

Feedback following an analysis of the Company’s investor 
base at each Board meeting and research notes by sell-side 
analysts is reported by the CEO. The Board also received 
analysts’ notes, and brokers’ briefings to ensure, as far as 
possible, a clear and up-to-date understanding of investors’ 
views. Information on investor sentiment is also provided to the 
Board by the Company’s brokers and financial PR advisers.

A list of the Company’s major shareholders can be found in the 
investor section of our website, and a list of notifiable holdings can 
be found on page 88 of the Directors’ Report.

These are regularly updated following the formal notification of 
movements to the Company.

The Company further communicates with shareholders through its 
Annual Report and Accounts, half-year announcements, trading 
updates and at the Company’s AGM. Such reports as well as other 
relevant announcements and related information are all available 
on the Group’s website, www.alliancepharmaceuticals.com. 

The website also offers a facility to sign up for email alert 
notifications of Company news and regulatory announcements.

BOARD EFFECTIVENESS REVIEW 
As required under the QCA Code, the Board continually monitors 
and improves its performance and evaluates its performance 
based on clear and relevant objectives. The Chair evaluates 
the performance of the Board annually to offer Directors an 
opportunity to discuss their contribution in terms of their skills 
and experience as well as identifying areas for improvement or 
development to enhance the capabilities of the Board as a whole. 

In last year’s Report we set out the feedback received following the 
2022 review, which focused on four key areas including Board 
planning and dynamics, focus on strategic performance, and 
Committee remit and Board engagement. During the year, the 
following progress was made which included:

 ›

 ›

 ›

Enhancing the Board’s planning framework to drive discipline 
and behaviours. The Chair encourages the NEDs to feed into 
the planning process any matters that they feel need to be 
brought to the Board for discussion. Improving the reporting 
to better support decision-making has been slower than 
expected and this continues to be kept under review to ensure 
greater focus on strategy and risk and less on operational 
matters. 
The strategy continues to be well formulated with more time 
dedicated to discussing progress against the strategy with 
ongoing commitment to understanding the impact of emerging 
trends and envision the longer-term plans in the healthcare 
sectors and markets.
The Committee Chairs worked with the Company Secretary to 
ensure their work is discharged effectively, reviewing business 
and compliance requirements in line with broader annual 
planning. Succession planning is being developed more 

strategically and the Company was pleased to appoint Jeyan 
Heper as Chief Operating Officer on the Board. 
The Board continues to work on improving its engagement with 
investors and employees. 

 ›

The 2023 evaluation consisted of one-to-one meetings between 
the Chair and each Director to discuss various matters relating to 
Board and Committee performance and their effectiveness. 

Results and outcomes were reviewed, summarised and circulated 
to Board members for discussion in February 2023. 

The table below sets out the key focus areas arising from the  
2023 review:

Areas of focus

Feedback and recommendations

Planning, 
reporting  
and risk

The Board can sometimes be too operationally focused. 
Further improvements will be made to ensure alignment of 
reporting against key risks and strategy and including less by 
way of detailed operational updates. 

Board structure 
and dynamics

Succession 
planning

Board 
engagement

Alliance has a relatively small but engaged Board which 
meets every month with members forming close working 
relationships. This is a strength, but it is also important to 
continue promoting healthy discussion and challenge. 
Having two additional board members is welcomed 
and they have been onboarded well. They add further 
perspective and experience to the discussions at the Board. 

The Nomination Committee will make it a priority to ensure 
conclusion of the ongoing succession plans, dealing with 
both long and short-term needs as required.

The Board needs to be more proactive when engaging 
with shareholders and will be working with the Head of IR 
and Communications and advisers to create shareholder 
communication and IR plans. The SID will be expected 
to take a leading role to promote good relations with the 
Company’s shareholders. 

The next review in relation to 2023 is scheduled for early 2024.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Financial Statements

Additional Information

69

N O M I N A T I O N   C O M M I T T E E   R E P O R T

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

“  Our succession plans remain focused on 
ensuring we retain a diverse leadership with the 
right skills and experience to grow the business.”

Jo LeCouilliard, Nomination Committee Chair

CHAIR’S STATEMENT
I became Chair of the Nomination Committee (‘the 
Committee’) shortly after the announcement that David Cook 
would be stepping down from the Board. I am pleased to 
be able to introduce the Committee’s Report which sets out 
its responsibilities and the activities of the Committee during 
the year.

This year the focus was on succession planning for the 
Chairmanship and at the Executive and senior levels of the 
organisation. This process included reviewing Board balance 
and Committee composition, diversity of people and the skills 
and experience needed to support growth and development.

The Committee, led by Kristof Neirynck, was able to work with 
Executive Directors and the Chief People and Infrastructure 
Officer to run the process for the nomination and appointment 
of a successor for the Chairmanship. As announced on  
18 May 2022, I am delighted to have accepted the role of 
Chair of the Board when David steps down.

The Committee also ran the process for the appointment of 
a new executive role of Chief Operating Officer and a new 
independent Non-executive Director to strengthen the Board’s 
skills and capabilities. We were pleased to announce the 
appointments of both Jeyan Heper and Martin Sutherland 
earlier this year. On 10 February 2023, we were pleased to 
welcome Martin Sutherland as a member of the Committee.

Should investors wish to discuss any aspects of the work of  
the Committee, I will be available to answer questions at  
this year’s AGM.

Jo LeCouilliard
Nomination Committee Chair
20 March 2023

For more information visit  
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 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
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Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

70

N O M I N A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

SKILLS & EXPERIENCE MATRIX

DIRECTOR

ROLE

GENDER

FINANCE

CONSUMER 
HEALTHCARE

PHARMA

INTERNATIONAL

GROWTH

FINANCIAL  
MARKETS*

Peter Butterfield

Andrew Franklin

Kristof Neirynck

David Cook

Jo LeCouilliard

Richard Jones

Jeyan Heper

Martin Sutherland

CEO

CFO

INED

INED

INED

INED

COO

INED

M

M

M

M

F

M

M

M

*   UK and overseas financial markets experience.

THE ROLE OF THE COMMITTEE
The Committee’s primary roles are to carry out a selection process 
for the appointment and reappointment of all Directors to the 
Board, and to review the structure, size, and composition of the 
Board (including in terms of skills, knowledge, experience and 
diversity). The Committee also reviews the leadership needs of the 
organisation and monitors succession planning for both Board and 
senior executive roles.

The framework of duties is set out in its Terms of Reference which 
are available on the Company’s website. Each year the Committee 
reviews its own performance and compliance with its Terms of 
Reference. 

MEMBERSHIP AND MEETING ATTENDANCE
Appointments to the Committee are made by the Board. During the 
year the Committee comprised four independent Non-executive 
Directors who have the right to attend meetings. Martin Sutherland 
joined the Committee in February 2023. Where appropriate, 
the Chief People and Infrastructure Officer and the CEO are 
invited to attend certain meetings of the Committee to support with 
discussions around succession planning and recruitment processes.

Members of the Committee have access to the Company 
Secretary, who attends and minutes all meetings. To enable 
the Committee to discharge its duties effectively, the Company 
Secretary is responsible for ensuring the Committee receives high-
quality, timely information. 

The Chair of the Committee reports to the Board on its 
proceedings after each meeting on all matters within its duties and 
responsibilities and will make any recommendations to the Board it 
deems appropriate.

During the year, the Committee held a total of eight meetings: 
two scheduled and six unscheduled. Members who are not 
able to attend unscheduled meetings offer their apologies and 
provide feedback to the Chair of the Committee in advance of 
meetings. The two unscheduled meetings were held to deal with 
the appointment of the successor to the Chair and review other 
executive and senior level succession plans. When discussing the 
succession to the Chairmanship of the Board, these meetings were 
not attended by Non-executive Directors who formed the subject 
of these discussions. Whilst David Cook attended these meetings, 
he did not chair them; they were chaired by Kristof Neirynck.

Member

David Cook

Jo LeCouilliard*

Kristof Neirynck

Richard Jones*

Role

Chair

NED

NED

NED

Status

Attendance

Independent

Independent

Independent

Independent

8/8

6/8

8/8

6/8

*  Board members were recused from meetings in which they were conflicted. 

Board gender diversity
Whilst certain diversity targets are not directly imposed on AIM 
companies, the Committee continues to monitor guidance and 
best practice in the market around the areas of gender and 
ethnicity, in particular the percentage targets set for FTSE main 
market listed companies. The Company’s Diversity and Inclusion 
Policy can be found on the Company’s website. 

The Committee is aware of and has discussed the benefits of 
diversity on the Board and at the senior management level as part 
of the review of succession planning and any Director appointment 
process. It remains committed to considering diversity when 
discussing appointments and succession plans. The Company 
and the Board always seek to search for, recruit and appoint the 
best available person based on aptitude and ability, regardless of 
gender, marital or civil partnership status, race, colour, nationality, 
ethnic or national origins, pregnancy, disability, age, sexual 
orientation, religion, or belief. The Committee discussed a range 
of areas such as diversity of thought, experience, gender, ethnicity, 
skills, nationality, and specific skills identified to strengthen and 
develop the knowledge base on the Board. 

With currently only one female member on the Board, the Board 
acknowledges that female representation on the Board is not 
where it needs to be, but ensures that focus is maintained at all 
stages of the Board recruitment process. The Company engages 
and works with specialist recruitment consultants to help identify 
talent and search for potential candidates that meet our objective 
criteria. Jo LeCouilliard will become the Company’s first female 
Chair with effect from the end of the 2023 AGM. 

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N O M I N A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

ACTIVITIES OF THE COMMITTEE

The duties and activities of the Committee during the year included:

Duties

Activity in 2022

Review the structure, size, and composition 
of the Board, including the independence 
of Directors, diversity, skills, knowledge, 
experience, and time commitments at least 
annually and prior to commencing any 
appointment process

Consider succession plans for Directors and 
other senior executives

• The Committee considers there to be an appropriate balance between Executive and Non-executive Directors on the Board. Having considered the guidelines on independence,  
on appointment as Chair, David Cook was independent and continues to be regarded by the Board as independent alongside Richard Jones, Jo LeCouilliard, and Kristof Neirynck.

• The Chair and Non-executive Directors hold appointments as Directors and/or senior management on a small number of other companies, as detailed in their biographies on pages 61 and 62. 

It is considered that the Chair and Non-executive Directors are not over-boarded and can allocate sufficient time and commitment to fulfil their duties to the Company.

• Prior to the search and recruitment process for new Directors, the Committee reviewed the skills, capabilities, diversity, and experience on the Board and concluded to specifically seek out skills 

and experience in overseas territories and a listed environment.

• The Committee worked closely with the Board and, with the support of the Chief People and Infrastructure Officer, developed strategies in support of progressive and orderly succession planning 
for Board and senior management. Planning included consideration of the challenges and opportunities facing the Company with careful evaluation of the skills and experience needed on the 
Board in the future. When developing these plans, the Directors are mindful of the need for a more diverse executive pipeline to help increase diversity levels in senior positions.
• Reviewed succession plans in relation to the Chief Executive Officer and other members of the senior leadership team and approved the appointment of Jeyan Heper to the Board.

Nominate and recommend candidates to fill 
Board vacancies and make recommendations 
to the Board on matters such as Committee 
membership, reappointment, and re-election 
of Directors

• The Committee is responsible for the selection process for the recruitment of Directors. This process is supported by the Chief People and Infrastructure Officer and the Company engaged the 

services of an external executive search and recruitment agency. The process is supported by a detailed recruitment process. Further information about the appointment and induction of Board 
Directors can be found in the Chair’s Report on Governance on page 65.

• As announced last year, the nine-year tenure of the Chair will come to an end in early 2023, after which he is no longer considered to be independent. Accordingly, during the year, the 

Committee considered succession for the role and shareholders were notified on 18 May 2022 that Jo LeCouilliard will become Chair of the Board following the 2023 AGM. Page 85 in the 
Remuneration Committee Report sets out the term of appointment for each Director.

• Recommended the appointment of Jeyan Heper as a new Chief Operating Officer and to the Board.
• Recommended the appointment of new Non-executive Director Martin Sutherland to the Board.

Reviewing the need for a Senior Independent 
Director (‘SID’)

• Each year the Nomination Committee considers whether it is appropriate to have a SID to act as a sounding board and intermediary for the Chair or other Board members. Richard Jones was 

appointed SID with effect from 1 February 2023.

Reviewing the outcomes of the Board 
evaluation insofar as these relate to 
composition and time commitment of Directors

• The Committee reviewed the outcomes from the annual evaluation of the Board insofar as these relate both to composition and time commitment from Non-executive Directors. The Committee 

keeps under review the Board’s composition to ensure it provides a sufficiently wide range of skills and experience to enable it to pursue its strategic goals and to address anticipated issues in the 
foreseeable future. This process includes reviewing the mix of skills, sector experience and financial, public markets and international experience.

Recommend annual re-election of directors 
at AGM

• In accordance with the Company’s Articles of Association, all Directors are subject to election or re-election by shareholders at the AGM. In line with good practice, the Committee 

recommended to the Board that five Directors, being eligible, put themselves forward for annual re-election and both Jeyan Heper and Martin Sutherland stand for election at the Company’s 
AGM.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

72

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

A U D I T   A N D   R I S K   C O M M I T T E E   R E P O R T

“  The Committee reviews the integrity of the financial 
statements and challenges systems of governance.”

Richard Jones, Audit and Risk Committee Chair

CHAIR’S STATEMENT
On behalf of the Audit and Risk Committee (‘the Committee’),  
I am pleased to introduce the Audit and Risk Committee Report. 
As a company admitted to AIM, we are guided by the QCA’s 
Audit Committee Guide and, when appropriate to do so, look 
to the UK Corporate Governance Code 2018 and to investor 
guidelines for best practice.

This report is intended to provide shareholders with information 
about the Committee’s responsibilities and report on the activities 
of the Committee during the year.

During the year, alongside our regular work carefully reviewing 
the Company’s annual financial statements and the associated 
accounting treatment and disclosures, efforts focused on the 
change of auditor. As detailed in last year’s Annual Report, we 
initiated a tender process for the 2022 audit and the Company 
was pleased to announce on 8 August 2022 the appointment 
of Deloitte LLP (‘Deloitte’) as the Group’s auditor. Andrew 
Wright is the lead audit partner and, as well as meeting up with 
Deloitte without management being present, I also meet Andrew 
regularly throughout the year.

There has also been a strong focus on the reporting of 
performance and accounting treatment in relation to our 
CBEC business in China, and acquisitions in the US: Biogix Inc. 
(Amberen™) and ScarAway™ the largest silicone-based scar 
treatment brand in the US, and the rights to sell Kelo-Cote™.

The Committee reviews the Group’s risk register quarterly, and 
believes that the Group strategy has the support of a management 
team who understand the risk management framework required 
to deliver it. In addition, the risk framework and risk register are 
shared with Deloitte, who consider and challenge the Committee 
on our reporting and disclosure requirements.

On 10 February 2023, we were pleased to welcome Martin 
Sutherland as a member of the Committee.

Richard Jones
Audit and Risk Committee Chair
20 March 2023

For more information visit  
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A U D I T   A N D   R I S K   C O M M I T T E E   R E P O R T  C O N T I N U E D

THE ROLE OF THE COMMITTEE
The Committee assists the Board with monitoring and reviewing 
the Company’s financial results and other reporting and has 
oversight of the effectiveness of risk management and systems of 
internal control. Its role is to provide confidence to shareholders 
on the integrity of our reported financial results and provide 
challenge to the external auditors and senior management.

The framework of duties is set out in its Terms of Reference, which 
are available on the Company’s website. Each year the Committee 
reviews its own performance and its Terms of Reference.

DUTIES OF THE COMMITTEE
The duties of the Committee include:

 ›

 ›

 ›

 ›

 ›

 ›

reviewing the management and reporting of financial 
matters, including key accounting policies;
reviewing the Annual Report and Accounts and advising the 
Board on whether, when taken as a whole, it is fair, balanced, 
and understandable and provides shareholders with the 
information necessary to assess the Company’s performance, 
business model and strategy;
considering the appointment of external auditors and the 
frequency of re-tendering and rotation of the audit;
overseeing the relationship with, and the independence and 
objectivity of, the external auditors;
setting policy in relation to the use of the external auditors for 
non-audit services;
advising the Board on the Company’s appetite for and 
tolerance of risk and the strategy in relation to risk management 
and reviewing any non-conformances with these;

 ›

 ›

reviewing the Company’s risk management and internal 
control systems and their effectiveness; and
reviewing the Company’s procedures for detecting fraud, 
bribery and corruption and ensuring arrangements are 
adequate for employees to raise concerns.

Members of the Committee have access to the Company 
Secretary who attends and minutes all meetings. To enable the 
Committee to discharge its duties effectively, the Company 
Secretary is responsible for ensuring the Committee receives 
high-quality, timely information. The Chair of the Committee works 
closely with the CFO and the finance department to ensure papers 
for meetings are comprehensive and comprehensible. When 
appropriate to do so, the Committee seeks the support of external 
advisers and consultants.

The Committee reports to the Board which includes reporting 
on any matters where it considers action or improvement is 
needed, including recommendation of remedial actions. The 
Chair of the Committee reports to the Board on its 
proceedings after each meeting on all matters, including any 
reporting issues and on estimates and judgements made in the 
preparation of financial statements. 

MEMBERSHIP AND MEETING ATTENDANCE
During the year, the Committee held a total of eight meetings: six 
scheduled and two unscheduled meetings, reporting on its 
activities to the Board. Members who are not able to attend 
unscheduled meetings offer their apologies and provide 
feedback to the Chair of the Committee In advance of meetings. 

The Committee comprised three independent Non-executive 
Directors who have the right to attend meetings. Martin Sutherland 
joined the Committee in February 2023.

Member

Richard Jones

David Cook

Jo LeCouilliard

Role

Chair

NED

NED

Status

Attendance

Independent

Independent

Independent

8/8

8/8

6/8

Committee membership and attendance
Appointments to the Committee are made by the Board following 
any recommendations from the Nomination Committee. Only 
members of the Committee have the right to attend meetings. 
During 2022, the three Non-executive Directors, all of whom have 
an accountancy qualification, review internal controls and financial 
reporting matters. They have a direct relationship with the external 
auditor. All members of the Committee have a mix of 
knowledge and skills gained through their experience of 
business, management practices including risk, the industry 
sector and have recent and relevant financial experience.  
The CEO, CFO, Group Head of Finance and Group Financial 
Controller are invited to attend all meetings, while other senior 
financial managers attend as appropriate.

The external auditor also attends the meetings to discuss the 
planning and conclusions of their work and meet with the 
members of the Audit and Risk Committee without any members 
of the executive team present after each meeting. The Audit and 
Risk Committee can call for information from management and 
consults with the external auditor directly if required.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

74

A U D I T   A N D   R I S K   C O M M I T T E E   R E P O R T  C O N T I N U E D

KEY ACTIVITIES OF THE COMMITTEE

Areas of focus

Key duties and responsibilities

Activities in the year ended 31 December 2022

Financial statements and 
narrative reporting

The content and integrity of financial statements 
and any formal announcements relating to 
financial performance, including review of 
the significant financial reporting judgements 
contained therein

 ›

Review of the financial statements and narrative reporting in the Annual Report and Accounts for 2021 and 2022 with 
reference to the reports being fair, balanced and understandable. This included a review of the appropriateness of the 
disclosures considering requirements and guidance under IFRS, the AIM Rules for Companies, Companies Act 2006 
requirements, FRC guidance and the QCA Corporate Governance Code 2018.
Review of the preliminary results and Annual Report and Accounts for the financial year ended 31 December 2021
 ›
Review of the unaudited half-year results to 30 June 2022.
 ›
Review of the preliminary results and Annual Report and Accounts for the financial year ended 31 December 2022.
 ›
 › Consideration of reports from the external auditor in respect of the Annual Report and Accounts from 1 January 2022 

to the date of this Report.

Going concern 

Matters that have informed the Board’s 
assessment of whether the Company is a 
going concern

 › A review of the going concern including methodology, assessment in support of the going concern assumption, 
concluding the expectation that the Group has adequate resources to continue in operation existence for the 
foreseeable future.

Accounting policies  
and standards

Key accounting estimates and judgements

 ›

In respect of the preparation of the financial statements for the year ended 31 December 2022, the Committee 
reviewed key accounting judgements and estimates including a review of the Group’s weighted average cost of 
capital (‘WACC’).
Review of intangible assets, including consideration of impairment under IAS 36.
Review of alternative performance measures.

 ›
 ›
 › Continued review and assessment under IFRS 15 and the revenue recognition in relation to a major cross-border 

e-commerce distribution agreement.

Risk management and 
internal controls

Financial and other internal controls and risk 
management systems, including the Group’s 
Principal Risks and Uncertainties

Review of the Group’s assessment of its control framework, including progress in enhancing the control environment.

 ›
 › A review of the business and corporate governance statement relating to the audit and risk management.
 › A review of the Group’s risk management and internal control systems and Group risk register.
 ›
 ›

Review of the Principal Risks and Uncertainties reported in the Annual Report & Accounts 2022.
Review of progress to establish an internal audit function.

For more information visit  
alliancepharmaceuticals.com

Regulatory and compliance risk

 ›

Review of the Company’s Whistleblowing policy and procedures.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

75

A U D I T   A N D   R I S K   C O M M I T T E E   R E P O R T  C O N T I N U E D

KEY ACTIVITIES OF THE COMMITTEE CONTINUED

Areas of focus

Key duties and responsibilities

Activities in the year ended 31 December 2022

Review of external 
auditor

The policy to control engagement of the 
external auditor to supply non-audit services

 ›

Review of feedback received from the outgoing auditor and consideration of whether there were any areas of 
financial oversight or governance to address concluding no changes were required.

 › Conduct a tender process for the change of auditor.
 ›

Review the terms of appointment, areas of responsibility and duties of the auditor including fees for the 2022 external 
audit and recommendation to the Board for approval.
Review of the scope and strategy for the 2022 external audit.
Review of the external auditor’s performance, independence, and objectivity meetings with the external auditor 
without management to consider any potential areas of concern.
Review and consideration of the external auditor’s findings and recommendations and management’s response from 
the audit of the years ended 31 December 2021 and 2022.

 ›
 ›

 ›

External auditor’s independence and objectivity 
and the effectiveness of the audit process

 › Meetings with the external auditor without management to consider any potential areas of concern.
 ›

Review and consideration of the external auditor’s findings and recommendations and management’s response from 
the audit of the years ended 31 December 2021 and 2022.

Terms of Reference

Reporting to the Board on how the Committee 
has discharged its responsibilities

 ›

The Committee reviewed its own Terms of Reference which are considered to be satisfactory. The Committee and 
Board were satisfied that the Committee and its members continue to operate effectively individually and collectively 
and had discharged all of the duties within its remit.

RISK MANAGEMENT AND INTERNAL CONTROLS
The Board has primary responsibility for the Group’s overall 
approach to risk management and systems of internal control 
and has delegated its oversight to the Committee.

At least once a year, the Board also reviews risk management 
and those risks the Board is not prepared to take are either 
avoided or, as far as possible, are mitigated and/or transferred 
to insurers.

During the year, the Committee has reviewed and reported on 
the identification, evaluation and management of risks facing the 
business and has considered the effectiveness of associated 
processes and controls to ensure a healthy balance between the 
risk we face and harnessing the opportunities that align with 
strategy to grow a strong and sustainable business.

The responsibilities surrounding risk management and internal 
control systems are designed to meet the needs of the size and 
complexity of the business. It takes into account the applicable 
requirements of pharmaceutical regulators in the various markets 
in which the business operates as well as the legal requirements 
of being a UK company admitted to AIM. Internal controls are 

designed to manage rather than eliminate risk and provide 
reasonable but not absolute assurance against material loss  
or misstatement.

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Effectiveness and independence of the external auditor
The Committee is responsible for agreeing the terms of 
engagement with the Company’s external auditor. The objectivity 
and independence of the external auditor is safeguarded by 
reviewing the auditor’s formal declarations, monitoring 
relationships between key audit staff and the Company, and 
tracking the level of non-audit fees payable to the external 
auditor. The Committee annually reviews the scope and fees for 
the annual audit of the Company.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

A U D I T   A N D   R I S K   C O M M I T T E E   R E P O R T  C O N T I N U E D

The key components of the current systems of internal controls are:

 › Clearly communicating Alliance’s values and strategy to 
ensure these are understood and people know what is 
expected

 › Developing business and financial plans that support the 

strategy
Reviewing policies and procedures to ensure these remain fit 
for purpose
Strengthening controls through enterprise resource planning
Regular reporting of actual performance relative to goals, 
budgets and forecasts
Ensuring there is a structure of accountability
Training and monitoring

 ›

 ›
 ›

 ›
 ›

INTERNAL AUDIT FUNCTION
The Committee asked management to establish an internal audit 
function and is monitoring the establishment of the internal audit 
function as we strengthen our internal audit capabilities by 
investing in people and systems to assist with reporting and 
auditing trails. This process is expected to complete in 2023.

SPEAK UP POLICY
The Company has a Speak Up Policy and procedures to help 
with the detection and prevention of fraud. Reviewed annually, 
the Policy was updated during the year and published on the 
Company’s Intranet and provides all employees access to a 
confidential forum in which it is possible to raise concerns about 
potential and perceived improprieties. Provided it is appropriate 
to do so, the process is managed by the Company Secretary in 
conjunction with Human Resources. The outcomes of any 
investigations carried out in accordance with the Policy is 
reported to the Committee.

EXTERNAL AUDITOR
Change of auditor
During the year, the Committee led a formal tender process in 
search of a new audit firm for the 2022 audit. The process 
included issuing an audit tender letter, timetable, audit scope and 
information on the Company. Potential firms were assessed 
against set criteria with quality and challenge being primary 
factors and in line with FRC recommended selection processes.

Following this process, we were pleased to notify the 
appointment of Deloitte on 8 August 2022, when KPMG stepped 
down as the Company’s auditor. KPMG did not participate in the 
tender process.

Deloitte’s reappointment requires the approval of shareholders at 
the AGM and accordingly, the Committee recommended that a 
resolution be proposed for their appointment at this year’s AGM.

Audit process
Each year, the Committee assesses the proposed audit plan for 
the external auditor’s review of the Company’s full-year financial 
statements. This plan sets out the scope of the audit, areas of 
significant risk of material misstatement, timetable and fees. 
Deloitte formally presented their findings to the Committee but 
throughout the auditing process there is regular dialogue and 
engagement with management with any significant matters or 
risks being communicated.

Prior to the Board’s approval of the Annual Report and Accounts, 
the Committee reviews with the auditor the representations set out 
in the management representation letter and reports to the 
Board. The auditor presents the Board with a management 
representation letter which the Committee will have reviewed and 
discussed with the auditor as part of its year-end meetings.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

77

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T

“ We balance our remuneration 
policies and practice with the size 
and complexity of our business.”

Jo LeCouilliard, Remuneration Committee Chair

CHAIR’S STATEMENT
On behalf of the Remuneration Committee (the ‘Committee’),  
I am pleased to introduce this year’s Remuneration Committee 
Report. As a company admitted to AIM, we are guided by the 
QCA’s Remuneration Committee Guide and, when 
appropriate to do so, look to the UK Corporate Governance 
Code 2018 and to investor guidelines for best practice. 

This year, we held several meetings to review our remuneration 
policy to ensure it remains appropriate for the size and 
complexity of our business. The Committee continues to 
believe that the Company’s current remuneration policy 
encourages and rewards the right behaviours and that any 
risks created by its structure are within the appetite of the 
Board. There were no changes to our Policy on Remuneration 
this year. Key activities of the Committee included:

 ›

 ›

reviewing our remuneration policies and remuneration 
levels (both fixed and variable) in the context of 
appropriate AIM market comparisons;
ensuring our policy continues to achieve its objectives 
and continues to attract, retain, and motivate a high-
quality management team to run the Alliance business 
successfully for our shareholders;

 ›

reviewing the remuneration for the acting CEO;

 ›
 › monitoring and making recommendations with respect to the 
level and structure of remuneration for senior management;
assessing the achievement of performance conditions and 
extent of vesting relating to share awards which matured 
in 2022;
approving the grant of share option awards under the 
Company’s share incentive plans to the Executive Directors 
and employees; and
reviewing the holding requirements under the Company’s 
Share Ownership Policy.

 ›

 ›

On the 10th February 2023, we were pleased to welcome 
Martin Sutherland to the Committee. The Committee continues 
to monitor trends and developments in relation to 
remuneration market practices and corporate governance, 
and welcomes views from its shareholders. I will be available 
to answer any shareholder questions on the Committee’s 
activities at this year’s AGM. In the meantime, I would like to 
thank our shareholders for their continued support.

Jo LeCouilliard
Remuneration Committee Chair
20 March 2023

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R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

THE ROLE OF THE REMUNERATION COMMITTEE
The role of the Committee is to ensure there is a formal process 
for considering executive remuneration. On behalf of the Board, 
it reviews the pay, benefits, and other terms of service of the 
Executive Directors of the Company and the broad pay strategy 
with respect to other senior executives. The framework of duties 
is set out in its Terms of Reference which are available on the 
Company’s website. 

Each year the Committee reviews its own performance and its 
Terms of Reference. Members of the Committee have access to 
the Company Secretary who attends and minutes all meetings. 
To enable the Committee to discharge its duties effectively, the 
Company Secretary is responsible for ensuring the Committee 
receives high-quality, timely information. 

The Chair of the Committee reports to the Board on its 
proceedings after each meeting on all matters within its duties 
and responsibilities, and will make any recommendations to the 
Board it deems appropriate. The Committee will also engage 
with the Nomination Committee when considering, for example, 
the appointment of Directors or contractual terms on termination.

MEMBERSHIP AND MEETING ATTENDANCE
Appointments to the Committee are made by the Board 
following recommendations from the Nomination Committee. 
Only members of the Committee have the right to attend 
meetings. However, where appropriate, the CEO, CFO and 
the Chief People and Infrastructure Officer are also invited to 
attend certain meetings of the Remuneration Committee. During 
the year, the Committee held a total of seven meetings: three 
scheduled and four unscheduled and reported on its activities to 
the Board. 

During the year, the Remuneration Committee comprised three 
independent Non-executive Directors and their attendance was 
as follows:

Member

Jo LeCouilliard

David Cook

Kristof Neirynck

Role

Chair

NED

NED

Status

Attendance

Independent

Independent

Independent

7/7

7/7

7/7

Martin Sutherland was appointed to the Committee in 
February 2023.

ACTIVITIES OF THE COMMITTEE
During the year, matters reviewed and considered by the 
Remuneration Committee included reviewing policies on 
remuneration, the external environment, market comparators, 
increases to annual base salaries, short-term and long-term 
reward structures, and assessing the extent to which targets have 
been achieved under the performance-related bonus scheme. 
When appropriate to do so, the Remuneration Committee seeks 
the support of its external advisers, Ellason LLP. They are members 
of the Remuneration Consultants Group, which sets out guidelines 
to ensure that any advice received is independent. Ellason LLP 
provides no other services to the Company and the Committee is 
satisfied that the advice received is objective and independent. 

No Directors or senior managers are involved in any decisions as 
to their own remuneration.

REMUNERATION POLICY
Remuneration policy tables
As the Company is admitted to AIM, it is not required to produce 
a formal remuneration policy or seek shareholder approval of 
that policy. However, we set out below additional information 
that the Committee believes will be most useful to shareholders 
and reflects remuneration practices that are appropriate for an 
AIM company of our size. The policy is designed to ensure our 
Executive Director pay arrangements remain supportive of and 
drive the strategy.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
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79

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

POLICY TABLE IN RESPECT OF EXECUTIVE REMUNERATION

Element

Policy

Element

Policy

Base salaries are reviewed annually to ensure they remain in line with other pharmaceutical/healthcare 
and other AIM companies and reflect the size and scope of the individual’s role. Within that frame of 
reference, the Company aims to be at or near the median level.
Annual base salaries increase and take effect from May each year. The Committee is committed to 
ensuring that salaries remain competitive relative to the AIM 100. Levels are set to attract and retain 
individuals to lead and drive forwards the agreed strategy for the Company.

Annual bonus 
continued

Chief Executive Officer 
A bonus of 20% of base salary, increasing on a sliding scale up to a maximum of 100% of base 
salary, is payable upon the achievement of financial performance targets. The bonus payable 
can be further increased by applying a personal performance multiplier. The maximum personal 
performance multiplier is 1.5x (i.e. up to an additional 50% of salary). The CEO’s potential maximum 
Annual Bonus opportunity is therefore 150% of base salary.

Base salary

Pension and 
other benefits

Executive Directors can participate in the Company’s defined contribution pension scheme. In line with 
all employees, only their base salaries are pensionable. The Company contributes twice the amount 
contributed by the employee up to a maximum of 10% of salary. When appropriate to do so, Executive 
Directors may take benefits as a salary cash supplement (which will ordinarily be reduced to take 
account of the employer National Insurance Contributions).
Other benefits in kind include life assurance, healthcare and the provision of a cash allowance in lieu of 
a company car.

Annual bonus

The delivery of the Group’s in-year, short-term corporate goals is incentivised by offering a cash-settled 
bonus (‘Annual Bonus’) linked to two factors:
• the achievement of budgeted levels of underlying profit before tax, which is the key metric the Board 

considers in monitoring corporate performance; and

Share incentive 
schemes

• personal performance of each Executive.
As part of this incentive strategy Executive Directors are eligible to participate in the all-employee 
Annual Bonus scheme. The level of that bonus is determined by first assessing whether the threshold 
level of financial performance has been achieved by the business and, once this has been achieved, 
applying a further multiplier which is determined by assessment of the Executive’s personal 
performance for the relevant year.
The financial targets are set at the start of each financial year – the targets are determined with the 
approval of the Remuneration Committee to ensure they incentivise the Executives and align with 
delivery of the Group’s strategy.
Personal performance is measured using various factors, including delivery of pre-set personal targets.
Based on a combination of financial and personal performance, the Annual Bonus that each of the 
Executives is able to earn is as follows:

Share 
ownership

Chief Financial Officer
A bonus of 20% of base salary, increasing on a sliding scale up to a maximum of 100% of base 
salary, is payable upon the achievement of financial performance targets. The bonus can be further 
increased by applying a personal performance multiplier. The maximum personal performance-related 
multiplier is 1.5x (up to an additional 40% of salary). The CFO’s potential maximum Annual Bonus 
opportunity is therefore 120% of base salary.

The Company operates two share incentive schemes to encourage a culture of long-term growth and 
performance that aligns with share ownership. Executive Directors can participate in both the market 
value Company Share Option Plan (‘CSOP’), and a nil-cost Long-Term Incentive Plan (‘LTIP’).
Any awards granted to the Executive Directors are subject to performance metrics which are reviewed 
regularly by the Committee, and the level of award is reviewed annually to ensure that the aggregate 
remuneration remains competitive.
Performance targets for Directors’ awards granted under the LTIP and CSOP continue to be based on 
Earnings Per Share (‘EPS’) and Total Shareholder Return (‘TSR’) related targets, assessed over a 
three-year performance period.
The maximum total market value of shares over which awards may be granted under the LTIP to any 
participant during any financial year is 100% of the participant’s salary. However, in exceptional 
circumstances, the Committee may, at its absolute discretion, grant a higher amount. The maximum 
market value of shares under the approved part of the CSOP shall not exceed HMRC approved limits. 
There is no limit on the market value of shares when granting unapproved share option awards.
Further information about the Company’s share incentive plans is set out on pages 81 and 82.

To align Directors and Senior Management’s interests with our shareholders, the Company operates a 
Share Ownership Policy.
When exercising share options, relevant employees are required to build a qualifying interest in shares 
or vested options capable of exercise that is equal to a percentage of their base salary. Ordinary 
shares are valued at their market value at the time of any calculation carried out to determine whether 
a qualifying interest has been established or needs to be increased. The CEO is required to build a 
qualifying interest equal to 200% of his base salary, while the CFO and COO are required to build an 
interest equal to 150% of their salary. Further information can be found on page 85 of this Report.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Financial Statements

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80

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

POLICY TABLE IN RESPECT OF NON-EXECUTIVE REMUNERATION

Remuneration/ Benefit

Application

Fees

Non-executive Directors of the Company receive a basic fee for the services provided to the Company. These are reviewed by the Board from time to time to ensure levels remain in line with comparable companies. 
There are no performance measures in relation to fees paid to Non-executive Directors.

DIRECTORS’ REMUNERATION
The aggregate remuneration payable to the Directors in respect of the period was as follows:

Peter Butterfield

Andrew Franklin

Nigel Clifford1

David Cook

Richard Jones

Jo LeCouilliard

Kristof Neirynck

Salary or fees

Other

Pension

Bonus

Total remuneration, excluding 
share options

Exercised share  
option gains

Total remuneration, including 
share options

2022

2021

2022

2021

2022

2021

2022

2021

2022

2021

2022

2021

2022

2021

356,083

335,500

12,235

12,377

31,514

28,998

239,200

226,667

11,474

11,922

20,846

22,667

–

15,000

88,000

82,667

49,458

45,750

49,458

45,750

47,201

3,844

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

829,400

755,178

23,709

24,299

52,360

51,665

_

_

_

–

–

–

–

–

238,889

399,832

615,764

155,940

271,520

417,296

–

–

–

–

–

–

15,000

88,000

82,667

49,458

45,750

49,458

45,750

47,201

3,844

394,829

905,469

1,225,971

–

–

–

–

–

–

–

–

363,146

399,832

978,910

–

–

–

–

–

–

271,520

417,296

–

15,000

88,000

82,667

49,458

45,750

49,458

45,750

47,201

3,844

363,146

905,469

1,589,217

1 Nigel Clifford retired from the Board as a Non-executive Director on 30 April 2021.

No Director received any remuneration from a third party in respect of their service as a Director of the Company.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

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Strategic Report

Governance

Financial Statements

Additional Information

81

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

BASE SALARY
During the year, the Committee undertook a review of market 
benchmarks, including companies of similar size and sector, to 
gauge the pay positioning of the executive directors and other 
senior management; the review concluded that our total 
remuneration levels were positioned materially below median.

To help improve the positioning, base salaries for the CEO and 
CFO were increased during the year from £338,250 to 
£365,000 for the CEO and from £230,000 to £243,800 for 
the CFO. These increases took effect on 1 May 2022. In 
addition, the Committee agreed an uplift of £7,000 per month to 
Andrew Franklin in recognition of his additional responsibilities as 
acting CEO since November 2022. Peter Butterfield earned his 
fixed pay whilst on leave.

The annual base salary for the COO is £275,000.

PENSION AND BENEFITS
The CEO and CFO received an employer pension contribution of 
twice the amount contributed by the Director up to a maximum of 
10% of salary.

The column headed ‘Other’ in the table above shows the value of 
benefits provided to each Executive Director, including a cash 
allowance in lieu of a company car and healthcare. The 
Executive Directors accrue retirement benefits through defined 
contribution (money purchase) schemes. The Company does not 
operate a defined benefit scheme. No Director or former 
Director received any benefits from a retirement benefits scheme 
that were not otherwise available to all members of the scheme.

ANNUAL BONUS
The Committee reviewed the achievement of actual underlying 
profit before tax (‘PBT’) against budgeted levels — the key metric 
for monitoring corporate performance. In addition, the 
Committee considered the personal performance of the 
Executive Directors as measured against various factors including 
pre-set personal objectives. 

No annual bonus payments have been paid to the Executive 
Directors in respect of the year ending 31 December 2022 as the 
required threshold level of PBT was not achieved.

NON-EXECUTIVE DIRECTORS’ FEES
An increase to Non-executive Directors’ fees was approved 
during the year and took effect on 1 May 2022.

The annual fee paid to David Cook as Chair is £90,000. Jo 
LeCouilliard and Richard Jones each receive an annual fee of 
£46,128 plus a Committee Allowance of £5,000 for chairing the 
Remuneration and Audit and Risk Committees, respectively. 
Kristof Neirynck’s annual fees increased to £47,736. 

No Committee Allowance is paid for the chairing of the 
Nomination Committee.

SHARE INCENTIVE AWARDS
The Company operates two share incentive schemes under 
which share options are granted to Executive Directors and 
senior management. More details on our share plans can be 
found in the Directors’ Report on page 89.

AWARDS UNDER THE ALLIANCE COMPANY SHARE 
OPTION PLAN 2015 (‘CSOP’)
During the year, as part of the Company’s annual award 
process, the Committee approved the award of market value 
share options to the Executive Directors and Senior 
Leadership Team (‘SLT’). The quantum of award is one share 
for every £2 of base salary and, where appropriate, may 
attract HMRC tax advantages.

On 29 September 2022, the Company granted Peter 
Butterfield 182,500 share options under the CSOP and 
Andrew Franklin 121,900 share options. These share options 
were granted with an exercise price of 58.2p per share 
(being the closing mid-market price of one 1p Ordinary share 
in the Company at close of trading on 28 September 2022). 
Based on the exercise price, the value of the awards as at the 
date of grant was equal to £106,215 for the CEO and 
£70,945 for the CFO. These awards will vest on the third 
anniversary from the date of grant, 28 September 2025, 
subject to meeting the EPS and TSR performance targets as set 
out on the following page.

AWARDS UNDER THE ALLIANCE LONG-TERM 
INCENTIVE PLAN 2019 (‘LTIP’)
The Committee also approved awards granted under the 
Company’s LTIP in the form of nil-cost options. These were 
granted on 29 September 2022 with a face value of 55% of 
base salary to Peter Butterfield, equal to £200,750 (344,931 
option awards); and 45% of base salary to Andrew Franklin, 
equal to £109,710 (188,505 option awards). The strike price 
used to calculate the quantum of awards was 58.2p per share 
(being the closing mid-market price of one 1p Ordinary share in 
the Company at close of trading on 28 September 2022). These 
awards will vest on the third anniversary from the date of grant, 
28 September 2025, subject to meeting the EPS and TSR 
performance targets on the following page.

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

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Financial Statements

Additional Information

82

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

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R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

MALUS AND CLAWBACK
All awards under the LTIP are subject to standard malus and 
clawback provisions which allow the Company, in certain 
circumstances, to either (i) terminate outstanding options, or (ii) 
seek repayment of after-tax value of options which have been 
exercised by an Executive which has been dismissed as a result 
of a set of prescribed irregularities including the discovery of 
material misstatement of results of the Company or Group; or a 
serious breach of the Company’s code of ethics has arisen; or a 
serious regulatory, or health and safety issue has occurred.

PERFORMANCE CONDITIONS
All options granted to Executive Directors before 2019 will 
only vest if targets for growth in the Company’s underlying 
diluted Earnings Per Share (‘EPS’) are met over a period of 
three years. EPS is an important metric which provides a 
strong incentive to drive the Group’s business over that 
longer-term period and to mitigate downside risks that could 
affect the Group’s profitability. Reputation risks could 
reasonably be expected to affect the share price, so the 
Executive is further incentivised to mitigate these exposures,  
if they wish to maximise the potential value of their options.

In 2019, the Committee reviewed performance targets as part of 
the introduction of the LTIP and introduced a second measure, in 
addition to EPS, based on Total Shareholder Return (‘TSR’). As 
such, all options granted in 2022 to Executives under the CSOP 
and LTIP are subject to EPS and TSR performance conditions. 
50% of the awards are subject to EPS and 50% are subject to 
TSR, equally weighted as set out below:

EPS Compound Annual Growth Rate 
over the performance period

% of award that vests (of 50%)

< 5% CAGR

5% –10% CAGR

0%

Calculated on a straight-line 
basis between 50% and 100%

> 10% CAGR

100%

CAGR: means compound annual growth rate.

EPS: means the underlying diluted earnings per share as presented in the Company’s 
published Annual Reports.

EPS Compound Annual Growth Rate: means the percentage of increase in the EPS of the 
Company calculated by reference to the difference between (i) the EPS as presented in the 
published Annual Report for the financial year ending 31 December 2021, to (ii) the EPS as 
presented in the published Annual Report for the financial year ending 31 December 2024.

EPS Performance Period: means the period from 31 December 2021 to 
31 December 2024 (inclusive).

TSR against the FTSE Small Cap Index 
(ex-Trusts) over the performance period % of award that vests (of 50%)

Less than the Index

Equal to the Index

0%

50%

Between the Index but less 
than 15% out-performance 
of the Index on a cumulative 
basis over the TSR performance 
period

Equal to or greater than 15% 
out-performance of the Index 
on a cumulative basis over the 
TSR performance period

Calculated on a straight-line 
basis between 50% and 100%

100%

Index: means the FTSE Small Cap Index, excluding investments trusts as determined by the 
Company’s nominated adviser.

TSR: means total shareholder return calculated by reference to the Company’s share price 
appreciation plus all dividend per share paid (based on ex dividend date) during the TSR 
Performance Period, and as determined by the Company’s Nominated Adviser at the end of 
the TSR Performance Period.

TSR Performance Period: means the period starting on the Grant Date and ending on the 
third anniversary of the Grant Date.

AWARDS VESTING DURING THE YEAR
On 5 December 2022, market value share options made in 
2019 under the CSOP to Peter Butterfield and Andrew Franklin 
vested 50% based on the achievement of the EPS target for 
the financial year ending 31 December 2021 of 6.30p (being 
RPI+2% per annum over the three-year performance period).  
The remaining 50% of the CSOP awards lapsed as the TSR 
element was not met.

Total Shareholder Return
3rd January 2022 to 29th December 2022

)
0
0
1
o

t

t
)
d
0
e
0
s
1
a
b
o
e
t
r
d
(
e
n
s
r
a
u
b
e
e
r
r
r
(
e
n
d
r
l
u
o
h
e
e
r
r
r
a
e
h
d
s
l
o
a
h
e
o
r
T
a
h
s

t

t

l

l

t

a
o
T

125

115
125
105
115
95
105
85
95
75
85
65
75
55
65
45
55
35
45
25
Dec
35
2021
25

Jan
2022

Feb

Mar

Apr May

Jun

Jul

Aug

Sep

Oct

Nov

Alliance
Mar

Feb

Dec
2021

Jan
2022
Alliance
Earnings Per Share

6.50

FTSE Small Cap (ex. Investment Trusts)
Apr May

Aug

Jun

Jul

FTSE AIM 100
Oct

Sep

Nov

FTSE Small Cap (ex. Investment Trusts)

FTSE AIM 100

)
p
(
S
P
E

)
p
(
S
P
E

6.50
6.25

6.25
6.00

6.00
5.75

5.75
5.50

5.50
5.25

Dec
2021

5.25

Dec
2021

Jan
2022

Jan
2022

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Feb

Mar

Apr

May

Source: Refinitiv Eikon as at 06 March 2023
Nov

Aug

Sep

Oct

Jul

Jun

Source: Refinitiv Eikon as at 06 March 2023

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Company Overview

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83

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

LTIPs granted in 2019 also vested to Peter Butterfield and Andrew Franklin vested at 50% based on 
the achievement of an EPS target for the financial year ending 31 December 2021 of 6.30p (being 
RPI+2% p.a. over the five-year performance period). The remaining 50% of the LTIP awards lapsed 
as the TSR element was not met.

Details of the number of shares vesting and the relevant exercise prices for these option awards are  
set out in the table below and on page 84. The closing mid-market price of Ordinary shares on  
31 December 2022 (being the last dealing day in the calendar year) was 53.0p and the range 
during the year was from 35.3p to 121.6p.

SHARE INCENTIVE AWARDS
Executive Directors hold options through the Company’s share option and long-term incentive  
plans. Details of options held under the Company’s employee share schemes by the Directors as at 
31 December 2022 and who served during the year are as shown below. Shares are retained as 
required to comply with the Company’s Share Ownership Policy for which details are provided on 
page 79.

Peter Butterfield

Type of award

CSOP Unapproved

CSOP Unapproved

CSOP Unapproved

LTIP

CSOP Unapproved

LTIP

CSOP Unapproved

CSOP Approved

LTIP

CSOP Approved

CSOP Unapproved

LTIP

* No shares were exercised during 2022.

Date of grant

Exercise price (p) 

Performance 
condition

No. of  
options granted

Vested

Exercised*

Lapsed

Number of options 
capable of exercise

Exercisable from

Exercisable 
to

27-Oct-16

05-Oct-18

05-Dec-19

05-Dec-19

23-Sep-20

23-Sep-20

29-Sep-21

29-Sep-21

29-Sep-21

29-Sep-22

29-Sep-22

29-Sep-22

47.50

81.60

76.90

Nil

73.70

Nil

102.80

102.80

Nil

58.20

58.20

Nil

EPS

EPS

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

1,000,000

1,000,000

500,000

1,250,000

1,250,000

137,500

196,684

165,000

246,269

139,943

29,182

180,970

1

182,499

344,931

68,750

98,342

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

68,750

98,342

500,000

27-Oct-21

27-Oct-26

1,250,000

05-Oct-21

05-Oct-28

68,750

98,342

05-Dec-22

05-Dec-29

05-Dec-22

05-Dec-23

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

23-Sep-23

23-Sep-30

23-Sep-23

23-Sep-24

29-Sep-24

29-Sep-31

29-Sep-24

29-Sep-31

29-Sep-24

29-Sep-25

29-Sep-25

29-Sep-32

29-Sep-25

29-Sep-32

29-Sep-25

29-Sep-26

3,872,979

2,417,092

500,000

167,092

1,917,092

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
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Financial Statements

Additional Information

84

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

Andrew Franklin

Type of award

CSOP Unapproved

CSOP Unapproved

CSOP Unapproved

CSOP Unapproved

CSOP Unapproved

CSOP Approved

CSOP Unapproved

LTIP

CSOP Unapproved

LTIP

CSOP Unapproved

LTIP

CSOP Unapproved

LTIP

Date of grant

Exercise price (p) 

Performance 
condition

No. of 
 options granted

Vested

Exercised*

Lapsed

Number of options 
capable of exercise

Exercisable from

Exercisable 
to

04-Dec-15

27-Oct-16

27-Oct-16

15-Sep-17

05-Oct-18

05-Dec-19

05-Dec-19

05-Dec-19

23-Sep-20

23-Sep-20

29-Sep-21

29-Sep-21

29-Sep-22

29-Sep-22

46.75

47.50

47.50

53.00

81.60

76.90

76.90

Nil

73.70

Nil

102.80

Nil

58.20

Nil

No

EPS

EPS

EPS

EPS

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

EPS & TSR

1,935,829

1,935,829

1,435,829

155,000

400,000

170,000

178,000

39,011

55,989

111,183

110,000

134,328

115,000

100,681

121,900

188,505

155,000

400,000

170,000

178,000

19,505

27,994

55,592

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

19,505

27,994

55,592

–

–

–

–

–

–

500,000

155,000

400,000

170,000

178,000

19,505

27,994

55,592

–

–

–

–

–

–

04-Dec-18

04-Dec-25

27-Oct-19

27-Oct-26

27-Oct-21

27-Oct-26

15-Sep-20

15-Sep-27

05-Oct-21

05-Oct-28

05-Dec-22

05-Dec-29

05-Dec-22

05-Dec-29

05-Dec-22

05-Dec-23

23-Sep-23

23-Sep-30

23-Sep-23

23-Sep-24

29-Sep-24

29-Sep-31

29-Sep-24

29-Sep-25

29-Sep-25

29-Sep-32

29-Sep-25

29-Sep-26

3,815,426

2,941,920

1,435,829

103,091

1,506,091

* Neither Peter Butterfield nor Andrew Franklin exercised any share options during the year.

DIRECTORS’ INTERESTS, SHAREHOLDINGS & SHARE OWNERSHIP POLICY
The Company operates a share ownership policy under which the Executive Directors and certain 
other employees are required when exercising options to acquire and maintain an interest in Alliance 
Pharma shares up to a percentage of base salary. The policy requires Executive Directors, when they 
exercise options, to retain shares in the Company with a value equal to 50% of the net gain (post 
costs and settlement of tax liabilities) until such time as the required level of shareholding is achieved.

Once an Executive Director has built a stake in the Company equal to the required levels, they are 
free to exercise without having to retain shares. Interests may also be maintained as a result of a 
Director acquiring Ordinary shares in the open market. The Company Secretary maintains a record 
of individual required levels and qualifying interests based on information provided by an individual 
subject to this policy and reports periodically to the Remuneration Committee regarding compliance. 
Pursuant to the policy, 50% of the value of any vested but unexercised awards count towards the 
holding requirements. Ordinary shares are valued at their market value at the time of any calculation 
carried out using the previous day’s closing middle market quotation.

For more information visit  
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85

R E M U N E R A T I O N   C O M M I T T E E   R E P O R T   C O N T I N U E D

DIRECTORS’ INTERESTS, SHAREHOLDINGS & SHARE OWNERSHIP POLICY 
CONTINUED
As at 14 March 2023, the Executive Directors hold the following interests in Ordinary shares of  
the Company:

DIRECTORS’ SERVICE CONTRACTS
All Executive Directors are employed under 12-month rolling service contracts. The services of all 
Executive Directors may be terminated (i) by the Company or individual giving 12 months’ notice or 
(ii) immediately, in the event that the Director is not re-elected by shareholders at an AGM.

Director

Peter Butterfield

Andrew Franklin

CEO

CFO

Percentage 
of salary

2022 Base 
salary

Shareholding

Vested but 
unexercised
awards

Value of 
holdings*

% achieved

200% £365,000

442,104

1,917,092

£371,233

150%

£243,800

128,384

1,506,092

£214,360

102%

88% 

Peter Butterfield

Chief Executive

22/02/2010

Andrew Franklin

Chief Financial Officer

28/09/2015

Executive  Director

Date of 
appointment

Date of
current contract

Notice period 
(Company)

Notice period 
(Director)

* At the closing market price on 13 March 2023: 66.1p.

Jeyan Heper

Chief Operating Officer 01/02/2023

05/08/2010 
Rolling 12 months

25/06/2015 
Rolling 12 months

11/01/2023 
Rolling 12 months

12 months

12 months

12 months

12 months

12 months*

12 months*

The following table shows the interests of the Directors (and their spouses and dependent children) in 
the shares of the Company.

Director

Peter Butterfield

Andrew Franklin

David Cook

Richard Jones

Jo LeCouilliard

Kristof Neirynck

At 31 December 2021

At 31 December 2022

Beneficial

442,104

128,384

234,129

15,000

–

–

Non-
beneficial

–

–

–

–

–

–

Total

Beneficial

442,104

442,104

128,384

128,384

234,129

234,129

15,000

15,000

–

–

–

–

Non-
beneficial

–

–

–

–

–

–

Total

442,104

128,384

234,129

15,000

–

–

* 6-months’ written notice during first 12 months of employment and thereafter not less than 12-months written notice by either the Company  

or the Director.

The Non-executive Directors are employed under letters of engagement which may be terminated 
by the Company by (i) giving the appropriate notice, or (ii) immediately, in the event that the Director 
is not re-elected by shareholders at an AGM.

Non-executive  Director

First date of 
appointment

Current  term

Unexpired  term

David Cook*

Chair & Independent NED

01/04/2014

4 years

Nil

Jo LeCouilliard

Independent NED

01/01/2019

5 years

Richard Jones

Independent NED

01/01/2019

5 years

Kristof Neirynck

Independent NED

01/12/2021

5 years

Martin Sutherland

Independent NED

01/02/2023

5 years

9 Months

9 Months

46 Months

58 months

* David Cook will step down as Chair of the Board with effect from the AGM.

The Executive Directors’ service contracts and Chair and Non-executive Directors’ letters of 
appointment are available for inspection by shareholders at the Company’s registered office or by 
emailing the Company Secretary at Company.Secretary@AlliancePharma.co.uk. 

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

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Financial Statements

Additional Information

86

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

E S G   C O M M I T T E E   R E P O R T

“    Running our business in a responsible 
way, minimises negative impacts so 
we can make a positive contribution.”

David Cook, ESG Committee Chair

CHAIR’S STATEMENT
It gives me great pleasure to introduce this year’s report from 
the ESG Committee (‘the Committee’). 

The following pages set out the Committee’s responsibilities 
and you can read about the activities the Committee 
discussed during the year. 

This year we have made significant strides into our 
commitment to becoming a more sustainable business and in 
setting our ESG priorities, ensuring that these priorities align 
with the Company’s strategy. The Committee continues to 
believe that operating our business in a responsible way, 
minimises negative impacts on people and planet and makes 
a positive contribution to society. 

A lot of ground has been covered in the 12 months since the 
last Committee’s report. We have witnessed progress in the 
Company’s Net Zero Carbon strategy; have come to 
understand our material sustainability issues, introduced or 
reviewed policies to strengthen our governance framework 
and improved our voluntary TCFD reporting.

I would like to thank those shareholders who also  
continue to work with us to help us better understand 
responsible investing.

You can also read more about our work on Sustainability 
on the Company’s website.

David Cook
ESG Committee Chair
20 March 2023

For more information visit  
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87

E S G   C O M M I T T E E   R E P O R T  C O N T I N U E D

THE ROLE OF THE COMMITTEE
The ESG Committee’s primary role is to review the overarching 
ESG vision for the Company, including climate change, and 
ensure that the priorities are anchored and are an integral part of 
the Company’s overall strategy.

DUTIES OF THE COMMITTEE
The duties of the Committee include:

 ›

 ›

 ›

 ›

 ›

 ›

 ›
 ›

To recommend the overarching ESG vision to the Board  
and ensure that ESG priorities are anchored at the top of  
the Company
To ensure ESG priorities are an integral part of the 
Company’s overall strategy 
To ensure that the views of stakeholder groups on ESG 
matters are solicited and understood to inform the Company’s 
long-term strategic decisions
To identify the relevant ESG priorities that most significantly 
impact the Company and its stakeholders, its reputation and 
public interest role
To assist the Board in defining and executing the Company’s 
strategy and agree the annual plan and targets relating to 
ESG matters
To review the Company’s performance against its annual 
plan and ESG targets, initiatives and commitments
To guide the Company’s ESG communication strategy
To ensure that ESG priorities are reflected in the Company’s 
culture through its purpose, vision, values and behaviours as 
well as its supplier code of conduct

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

MEMBERSHIP AND MEETING ATTENDANCE
All Board members currently attend Committee meetings. During 
the year, the Committee held two scheduled meetings and 
reported on its activities to the Board.

ACTIVITIES OF THE COMMITTEE
An overview of our approach and sustainability framework can 
be found on pages 29 to 30 and can be found in our Online 
Sustainability Report on our website.

Member

David Cook

Peter Butterfield

Andrew Franklin

Jo LeCouilliard

Richard Jones

Kristof Neirynck

Role

Chair

CEO

CFO

NED

NED

NED

Status

Attendance

Independent

–

–

Independent

Independent

Independent

2/2

2/2

2/2

2/2

2/2

2/2

The Committee works closely with the SLT, Investor Relations and 
our Corporate Sustainability Lead who are invited to attend 
meetings. Others are invited to attend as appropriate to support 
the Committee with discussions. 

Activities
 ›

Reviewed 2022 and 2023 objectives and sustainability 
framework and initiatives 
Established a sustainable packaging strategy programme to 
review the Group’s product portfolio
Increased supply chain oversight through “Know your 
Supplier” and published our Partner Code of Conduct

 ›

 ›

 › Developed the carbon action plan which includes 

understanding what the Company’s supply chain are doing 
to reduce their Scopes 1,2 and 3 emissions

 › Outlined current investment into environmental strategy and 
carbon action plan by introducing EV schemes to encourage 
behavioural changes

During the year, the Committee also invited ESG consultants to 
present on the work that they have been doing with the business 
on Net Zero Carbon strategy, understanding the Company’s 
Scope 1, 2 and 3 emissions and setting the carbon action plan. 

 › Continued to work with the Company’s appointed energy 
consultancy firm to help shape the medium-term ambition, 
particularly in the areas of TCFD and Scope 3 emissions, 
supply chain management and development of key metrics

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88

D I R E C T O R S ’   R E P O R T

SCOPE OF THIS REPORT
The Directors present their Annual Report, together with the 
audited financial statements of the Company and the Group, for 
the year ended 31 December 2022.

The Directors’ Report, required under the Companies Act 2006, 
includes and comprises the Directors’ biographies on pages 
61 and 62, the Governance statement on pages 58 to 68, the 
Remuneration Committee Report on pages 77 to 85 and the 
Strategic Report on pages 06 to 56.

As permitted under the Companies Act 2006, certain matters 
which would otherwise need to be included in this Directors’ 
Report have instead been discussed in the Strategic Report on 
pages 06 to 56. These matters include any important post-balance 
sheet events, the likely future developments in the business of the 
Company and its subsidiaries, the activities of the Company and its 
subsidiaries in the field of research and development.

Principal activities
The principal activity of the Company is to act as a holding 
company. The principal activity of the Group is the acquisition, 
marketing and distribution of consumer healthcare and 
pharmaceutical products.

Branches
A list of the Group’s subsidiaries and associated undertakings 
can be found on pages 128 and 129 under note 13 to the 
financial statements. There are no branches of the Company 
outside the UK. Alliance Pharmaceuticals GmbH, a company 
within the Alliance Group, has a Swiss branch which operates 
under the name Alliance Pharmaceuticals GmbH Düsseldorf, 
Zweigniederlassung Uster.

Directors
Names and biographical details of the Directors of the Company 
at the date of this Report are shown on pages 61 and 62. The 
rules setting out the powers of Directors, their appointment and 
replacement are set out in the Company’s Articles of Association. 
Further information on the associated process can be found on 
page 70 of the Nomination Committee Report.

Details of Executive Directors’ service contracts and letters of 
appointment for Non-executive Directors can be found in the 
Remuneration Report on page 85. All Directors put themselves 
forward for annual re-election at the Company’s AGM.

Directors’ indemnities
The Company’s Articles of Association contain provisions for 
Directors to be indemnified (including the funding of defence 
costs) to the extent permitted by the Companies Act 2006.

This indemnity would only be available if judgement was given 
in the individual’s favour, or he or she was acquitted, or relief 
under the Companies Act 2006 was granted by the court. There 
were no qualifying pension scheme indemnity provisions in force 
during the year.

Share capital and shareholders’ rights
The Company’s issued share capital as at the 17 March 2023 is 
539,995,086 Ordinary shares of 1p each. Each Ordinary share 
carries one vote at general meetings of the Company. There 
are no restrictions on the transfer of Ordinary shares other than 
restrictions which may from time to time be imposed by law. The 
Company is not aware of any agreements between shareholders 
that may restrict transfer of securities or voting rights.

The Company has no shareholder authority to acquire its 
own shares.

Dividends
The Board declared an interim dividend in respect of the year 
ending 2022 of 0.592p per share (2021: 0.563p) which was 
paid to shareholders on 19 January 2023. The Directors are 
recommending a final dividend of 1.184p per share (2021: 
1.128p) which, subject to shareholders’ approval at the AGM on 
the 25 May 2023, will be paid on 18 July 2023 to shareholders 
on the register at close of business on 23 June 2023.

The total dividend paid and proposed in respect of the year 
ended 31 December 2022 is therefore 1.776p per share 
(2021: 1.691p).

Substantial shareholdings
As at 17 March 2023, as required under AIM and certain 
disclosure rules, the Company has been notified of the major 
shareholdings in the table below. Both the number of shares 
held, and the percentage holding ,are stated as at the latest 
date of notification to the Company. Details of all major 
shareholdings can also be found in the Investor section of the 
Company’s website.

Shareholder

DBAY Advisors Limited

Slater Investment

Van Lanschot Kempen

Rathbone plc

Royal Bank of Canada

Fidelity Mgt & Research

Investec Group

Mr John Dawson

Number of 
shares held

Percentage of 
issued share 
capital

55,734,204

10.32%

51,906,041

49,854,026

20,879,002

20,645,236

19,644,025

17,264,547

16,200,462

9.61%

9.23%

3.87%

 3.82%

3.64%

3.20%

3.00%

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
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89

D I R E C T O R S ’   R E P O R T   C O N T I N U E D

COMPANY SHARE INCENTIVE PLANS
The Company operates two incentive share plans.

The Alliance Company Share Option Plan 2015 (‘CSOP’)
For many years, the Company has operated a CSOP under 
which all employees are eligible to receive awards in the form of 
market value options. At the discretion of the Committee, awards 
are typically granted subject to a three-year vesting period and 
following maturity, participants have a seven-year period in 
which to exercise their options.

Options awarded are based on one share for every £2 
of salary and where appropriate may attract HMRC tax 
advantages. Employees based outside of the UK will receive 
non-tax advantaged share option awards and, where this is not 
possible, the Committee considers awards in the form of share 
appreciation rights.

All awards granted to Executive Directors and Senior 
Management are subject to performance conditions. These are 
explained in the Remuneration Committee Report on page 81.

The Alliance Long-Term Incentive Plan 2019 (‘LTIP’)
In 2019, the Company introduced the LTIP which forms part of the 
remuneration strategy for the Executive Directors and members 
of the Senior Leadership Team. Awards are granted in the form 
of nil-cost share options based on a percentage of base salary. 
All awards granted under the LTIP are subject to performance 
conditions and malus and clawback provisions. Subject to 
achieving the performance conditions set by the Committee, such 
awards will vest three years from the date of grant and participants 
will have 12 months in which to exercise any vested award.

Details in relation to awards granted to the Company’s Executive 
Directors are contained in the Remuneration Report on pages  
83 and 84.

Employee Benefit Trust (EBT/Trust) and management  
of dilution
The Company manages dilution rates within the standard 
guidelines. In 2017 the Group established the Alliance Pharma 
Employee Benefit Trust to facilitate the acquisition of Ordinary 
shares in the Company for the purpose of satisfying awards 
granted under share option schemes. The Group has been 
operating the Trust to help manage dilution limits in line with 
good practice.

The Trust is administered by an independent Trustee who 
operates the Trust independently of the Group. The EBT is a 
discretionary trust, the sole beneficiaries being employees 
(including Executive Directors) of the Group who have received 
applicable awards.

The Trustees must act in the best interests of the beneficiaries as a 
whole and will exercise their discretion in deciding whether or not 
to act on any recommendations proposed by the Company. Any 
assets held by the Trust would be consolidated into the Group’s 
financial statements. The Company may grant awards on the 
basis that it is the Company’s intention to settle the exercise of 
awards through shares purchased in the open market on an arm’s 
length basis. Awards granted and settled in this way are not 
included in the Company’s headroom and dilution calculation. 
The Group may fund (although it has not yet needed to and 
therefore has not done so) the EBT to purchase on the EBT’s own 
account shares in the Company on the open market. This is in 
return for the EBT agreeing to use the shares in the Company 
that it holds to satisfy certain outstanding awards made under 
the Company’s share option schemes. The purchasing in the 
market of shares to satisfy the exercise of options places a cash 
requirement on the business. To date, no shares have been 
purchased by the Trust for satisfaction of outstanding or future 
share option awards.

To further help manage dilution limits, and where appropriate 
and agreed with the Committee, share options are net settled 
upon exercise.

Employee share dealing and share ownership
In accordance with AIM Rule 21, all employees are made 
aware of and are required to comply with the Company’s 
Share Dealing Policy when dealing in the Company’s shares or 
exercising options over shares. The Dealing Code sets out the 
rules relating to close periods, clearance procedures, time frames 
and disclosure requirements.

The Company operates a share ownership policy under 
which the Executive Directors and certain other employees are 
required, when exercising options, to acquire and maintain an 
interest in Alliance Pharma shares up to a percentage of base 
salary, details of which can be found on page 84.

Accounting policies, financial instruments and risks
Details of the Group’s financial instruments and financial risk 
management disclosures can be found in note 21 of the Group 
financial statements on pages 133 to 137.

Charitable donations
During the year ended 31 December 2022, the Group 
contributed £58,790 (2021: £25,635) to charitable causes.

Political donations
No political donations or contributions were made, or political 
expenditure incurred during the period.

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
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 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

58

60

61

63

69

72

77

86

88

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

90

D I R E C T O R S ’   R E P O R T   C O N T I N U E D

Directors’ obligations to the auditor
The Directors confirm that: (a) so far as each of the Directors 
is aware, there is no relevant audit information of which the 
Company’s auditor is unaware; and (b) they have each taken 
all the steps that they ought to have taken as Directors to make 
themselves aware of any relevant audit information and to establish 
that the auditor is aware of that information. This statement is given 
in accordance of section 418 of the Companies Act 2006.

Company’s auditor
The Company announced the appointment of Deloitte LLP on  
8 August 2022 to fill a casual vacancy until the next AGM. 
Deloitte LLP has expressed its willingness to be formally 
appointed as the Company’s auditor and a resolution will be 
proposed at the AGM.

Annual General Meeting

This year’s AGM will be held on 25 May 2023, the business of 
which is set out in the Notice of Meeting. A circular containing the 
Notice of Meeting together with an explanatory letter from the 
Chair accompanies the Annual Report and is also available on 
the Company’s website.

Please note that following the Company’s move to electronic 
communications, we are no longer producing hard copy 
forms of proxy. These are available on request from the 
Company’s Registrars.

Electronic communications
Shareholders are encouraged to move away from hard copy 
Company communications. This means that, instead of being 
obliged to send Annual Reports, notices of shareholder meetings 
and other documents to shareholders in hard copy by post, 
the Company can instead elect to publish them on its website 
at www.alliancepharmaceuticals.com. Using the website and 

email allows us to reduce printing and postage costs and it is 
better for many shareholders who can choose and access just the 
information they need, from the website, at any time.

Totals 
The total consumption (kWh) figures for reportable energy 
supplies are shown as follows:

Shareholders still have the right to ask for paper versions of 
shareholder information, but we are strongly encouraging all 
shareholders to consider the electronic option.

Shareholders can also vote electronically using the following link, 
www.signalshares.com/. Registering your details on Link’s share 
portal also gives shareholders easy access to information about 
their shareholdings and the ability to vote at general meetings or 
appoint a proxy to vote.

COMPLIANCE WITH THE STREAMLINED ENERGY AND 
CARBON REPORTING REQUIREMENTS
Annual reporting figures 
The total consumption and emissions figures for energy supplies 
reportable by the Company.

Consumption (kWh) and greenhouse gas emissions 
(tCO2e) totals 
The following figures show the consumption and associated 
emissions for this reporting year for our operations, with figures 
from the previous reporting period included for comparison. 

Scope 1 consumption and emissions relate to direct combustion 
of natural gas, and fuels utilised for transportation operations, 
such as company vehicle fleets. 

Scope 2 consumption and emissions relate to indirect emissions 
relating to the consumption of purchased electricity in day-to-
day business operations. 

Scope 3 consumption and emissions relate to emissions resulting 
from sources not directly owned by us. This relates to grey fleet 
(business travel undertaken in employee-owned vehicles) only. 

Utility and Scope

Grid-supplied electricity (Scope 2)

Gaseous and other fuels (Scope 1)

Transportation  
(Scope 1 and 3)

Total

2022 Consumption 
(kWh)

2021Consumption 
(kWh)

229,932

8,604

193,853

432,389

256,103

10,644

144,186

410,933

The total emission (tCO2e) figures for reportable energy supplies 
are set out below. Conversion factors utilised in these calculations 
are detailed in the appendix on page 91:

Utility and Scope

Grid-supplied electricity (Scope 2)

Gaseous and other fuels (Scope 1)

Transportation  
(Scope 1 and 3)

Total

2022 Consumption 
(tCO2e) 

2021 Consumption 
(tCO2e) 

44.46

1.57

45.38

91.42

54.38

1.95

33.68

90.01

Intensity metric 
An intensity metric of tCO2e per £m turnover has been applied 
for our annual total emissions. The methodology of the intensity 
metric calculations are detailed in the appendix on page 91,  
and the results of this analysis are shown as follows:

Intensity Metric

tCO2e/£m turnover
tCO2e/£m headcount

2022 Intensity 
Metric

2021 Intensity 
Metric

0.79

0.48

0.70

0.50

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Financial Statements

Additional Information

91

D I R E C T O R S ’   R E P O R T   C O N T I N U E D

Energy efficiency improvements 
We are committed to year-on-year improvements in our 
operational energy efficiency. As such, a register of energy 
efficiency measures available to us has been compiled, with a 
view to implementing these measures in the next five years. 

Measures ongoing and undertaken through 2022  
In 2022, we submitted an application for full planning permission 
and listed building consent for the installation of solar PV panels 
on the roof of our Avonbridge site.

Measures prioritised for implementation in 2023
Subject to receipt of the required permissions and consents, 
we plan to progress with the installation of the solar PV panels 
in 2023.

Appendix to SECR
Reporting methodology 
Scope 1, 2 and 3 consumption and CO2e emissions data 
has been calculated in line with the 2019 UK Government 
environmental reporting guidance. Emissions Factor Database 
2022 version 1 has been used, utilising the published kWh gross 
calorific value (CV) and kgCO2e emissions factors relevant for 
reporting period 01/01/2022 – 31/12/2022. 

Estimations undertaken to cover missing billing periods for 
properties directly invoiced to Alliance were calculated on a 
kWh/day pro-rata basis at the meter level. These estimations 
equated to 8% of reported consumption.

For properties where Alliance is indirectly responsible for utilities 
(i.e. via a landlord or service charge), an average consumption 
for properties with similar operations was calculated at meter 
level and applied to the properties with no available data. These 
full-year estimations were applied to one electricity supply and 
one gas supply.

Intensity metrics have been calculated using total tCO2e figures, 
and the selected performance indicator agreed with Alliance for 
the relevant report period:

 ›

use the going concern basis of accounting unless they either 
intend to liquidate the Group or the parent Company or to 
cease operations, or have no realistic alternative but to do so.

 ›
 ›

Total UK turnover in 2022: £115.5m (2021: £128.4m)
Total UK headcount in 2022: 190 (2021: 179) 

Directors’ Responsibilities Statement
The Directors are responsible for preparing the Annual Report 
and the Group and Parent Company financial statements in 
accordance with applicable law and regulations.

Company law requires the Directors to prepare Group and 
Parent Company financial statements for each financial 
year. Under the AIM Rules of the London Stock Exchange 
they are required to prepare the Group financial statements 
in accordance with UK-adopted international accounting 
standards and applicable law and they have elected to prepare 
the parent Company financial statements on the same basis.

Under company law, the Directors must not approve the financial 
statements unless they are satisfied that they give a true and fair 
view of the state of affairs of the Group and parent Company 
and of the Group’s profit or loss for that period. In preparing 
each of the Group and Parent Company financial statements,  
the Directors are required to:

 ›

select suitable accounting policies and then apply them 
consistently;

 › make judgements and estimates that are reasonable, relevant 

 ›

 ›

and reliable;
state whether they have been prepared in accordance with 
UK-adopted international accounting standards;
assess the Group and Parent Company’s ability to continue 
as a going concern, disclosing, as applicable, matters related 
to going concern; and

The Directors are responsible for keeping adequate accounting 
records that are sufficient to show and explain the parent 
Company’s transactions and disclose with reasonable accuracy 
at any time the financial position of the Parent Company and 
enable them to ensure that its financial statements comply with 
the Companies Act 2006. They are responsible for such internal 
control as they determine is necessary to enable the preparation 
of financial statements that are free from material misstatement, 
whether due to fraud or error, and have general responsibility for 
taking such steps as are reasonably open to them to safeguard 
the assets of the Group and to prevent and detect fraud and 
other irregularities.

Under applicable law and regulations, the Directors are also 
responsible for preparing a Strategic Report and a Directors’ 
Report that comply with that law and those regulations.

The Directors are responsible for the maintenance and integrity 
of the corporate and financial information included on the 
Company’s website. Legislation in the UK governing the 
preparation and dissemination of financial statements may differ 
from legislation in other jurisdictions.

Chris Chrysanthou
Group General Counsel & Company Secretary
20 March 2023

Governance
 Chair’s Introduction 

Our Governance Structure 

Board of Directors 

Governance 

Nomination Committee Report 

Audit and Risk Committee Report 

Remuneration Committee Report 

ESG Committee Report 

Directors’ Report 

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60

61

63

69

72

77

86

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Financial  
Statements

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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REPORT ON THE AUDIT OF THE FINANCIAL STATEMENTS
1.  Opinion
In our opinion:

 ›

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the financial statements of Alliance Pharma plc (the ‘parent company’) and its subsidiaries (the 
‘group’) give a true and fair view of the state of the group’s and of the parent company’s affairs 
as at 31 December 2022 and of the group’s profit for the year then ended;
the group financial statements have been properly prepared in accordance with United 
Kingdom adopted international accounting standards; 
the parent company financial statements have been properly prepared in accordance with 
United Kingdom adopted international accounting standards and as applied in accordance 
with the provisions of the Companies Act 2006; and
the financial statements have been prepared in accordance with the requirements of the 
Companies Act 2006.

We have audited the financial statements which comprise:

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the consolidated income statement;
the consolidated statement of comprehensive income;
the consolidated balance sheet;
the company balance sheet;
the consolidated statement of changes in equity;
the company statement of changes in equity;
the consolidated and company cash flow statements; and
the related notes 1 to 31.

The financial reporting framework that has been applied in their preparation is applicable law and 
United Kingdom adopted international accounting standards and, as regards the parent company 
financial statements, as applied in accordance with the provisions of the Companies Act 2006.

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2.  Basis for opinion
We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs 
(UK)) and applicable law. Our responsibilities under those standards are further described in the 
auditor’s responsibilities for the audit of the financial statements section of our report. 

We are independent of the group and the parent company in accordance with the ethical 
requirements that are relevant to our audit of the financial statements in the UK, including the 
Financial Reporting Council’s (the ‘FRC’s’) Ethical Standard as applied to listed entities, and we 
have fulfilled our other ethical responsibilities in accordance with these requirements. 

We believe that the audit evidence we have obtained is sufficient and appropriate to provide a 
basis for our opinion.

3.  Summary of our audit approach

Key audit matters

The key audit matters that we identified in the current year were:

Materiality

Scoping

 › Valuation of the Amberen Cash Generating Unit (‘CGU’)
 ›

Recoverability of Trade Receivables for a significant distributor 
(‘distributor’)

The materiality that we used for the Group financial statements was 
£1,500,000 which was determined on the basis of profit before tax 
adjusted for impairment. 

Our group scoping results in 82% of group revenues, 81% of group profit 
before tax, and 95% of group net assets being subject to full scope audit 
procedures.

Significant changes 
in approach

The valuation of the Amberen Cash Generating Unit; and the recoverability 
of trade receivables for a significant distributor are new key audit matters in 
the current year.

In the prior year the key audit matters identified by the predecessor auditor 
included the impairment of brand assets. 

The predecessor auditor also identified the CMA infringement decision; 
the accounting treatment of costs related to cloud-based software 
arrangements; and the recoverability of parent company’s investment in 
subsidiaries as additional key audit matters. We do not consider these to be 
key audit matters in the current year.

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4.  Conclusions relating to going concern
In auditing the financial statements, we have concluded that the directors’ use of the going concern 
basis of accounting in the preparation of the financial statements is appropriate.

Our evaluation of the directors’ assessment of the Group’s and Parent Company’s ability to 
continue to adopt the going concern basis of accounting included:

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assessing the financing facilities available to the group, including the nature of available 
facilities, repayment terms and required covenants;
assessing the assumptions and sensitivity scenarios used in the forecasts;
assessing management’s identified potential mitigating actions and the appropriateness of the 
inclusion of these in the going concern assessment;
assessing the historical accuracy of forecasts prepared by management;
testing the clerical accuracy and appropriateness of the model used to prepare the forecasts;
reading analyst reports, industry data and other external information to determine if it provided 
corroborative or contradictory evidence in relation to assumptions used;
evaluating the disclosures made within the financial statements.

Based on the work we have performed, we have not identified any material uncertainties relating 
to events or conditions that, individually or collectively, may cast significant doubt on the Group’s 
and Parent Company’s ability to continue as a going concern for a period of at least twelve months 
from when the financial statements are authorised for issue.

Our responsibilities and the responsibilities of the directors with respect to going concern are 
described in the relevant sections of this report.

5.  Key audit matters
Key audit matters are those matters that, in our professional judgement, were of most significance 
in our audit of the financial statements of the current period and include the most significant 
assessed risks of material misstatement (whether or not due to fraud) that we identified. These 
matters included those which had the greatest effect on: the overall audit strategy, the allocation of 
resources in the audit; and directing the efforts of the engagement team.

These matters were addressed in the context of our audit of the financial statements as a whole, 
and in forming our opinion thereon, and we do not provide a separate opinion on these matters.

5.1  Valuation of Amberen Cash Generating Unit (‘CGU’) 

Key audit matter 
description

Brand intangible CGUs are valued at £282.2m and allocated goodwill is valued at £21.5m. 
The valuation of brand CGUs is dependent upon a number of estimates, including future 
growth forecasts, assumed margins, long term growth, working capital requirements and the 
selected discount rate. 

The Amberen brand CGU has a fair value of £105.4m, following an impairment recognised 
during the year of £12.0m in respect of allocated goodwill. 

Our key audit matter relates to the revenue growth and discount rate assumptions linked to 
the Amberen CGU, due to the significant sensitivities and judgement linked to each input, 
with reasonable possible changes leading to a material difference. Where budgeted growth 
rates are not achieved; or where interest rates continue to rise, further impairment may be 
required.

Note 2.3 to the financial statements provides details of the key sources of estimation 
uncertainty in respect of intangible assets.

Note 2.9 to the financial statements sets out the group’s accounting policy for intangible 
assets acquired as part of a business combination (Brands, Patents and Distribution Rights), 
goodwill and impairment of assets; and outlines the key assumptions involved in the 
intangible asset impairment assessment.

Note 11 to the financial statements outlines sensitivity analysis for reasonable possible 
changes in two key assumptions which could cause the carrying amount to exceed the 
recoverable amount.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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5.  Key audit matters continued
5.1  Valuation of Amberen Cash Generating Unit (‘CGU’) continued

5.2  Recoverability of trade receivables for a significant distributor (‘distributor’) 

How the scope of our 
audit responded to the 
key audit matter

We obtained an understanding of the relevant controls over management’s impairment 
assessment.

Key audit matter 
description

We considered indicators of impairment including with reference to historical performance, 
external market data, and assessment of the group’s future strategy and budgets.

We challenged the revenue growth assumptions used in the cash flow forecasts through 
enquiries of the finance teams and commercial teams within the United States and the United 
Kingdom, as well as the directors of the company to understand the performance of the 
brand.  

We involved our valuations specialists to estimate an appropriate discount rate with 
reference to market data and compared that to the rate used by management.

We tested the arithmetical accuracy of management’s impairment models and checked these 
for consistency with approved forecasts.

We assessed the accuracy of management’s historical forecasts; and we evaluated the 
impact of these on the current year forecasts.

We assessed sensitivities to calculations prepared by management for contradictory and 
confirmatory evidence, to determine the impact on headroom of reasonably possible 
changes in assumptions.

How the scope of our 
audit responded to the 
key audit matter

Key observations

Based on our work performed, we concur with management’s assessment of the valuation 
of the Amberen brand CGU. We consider management’s reasonable case sensitivity 
disclosures to be appropriate.

A distribution agreement is held for the sale of cross-border e-commerce sales of the  
Kelo-Cote product to China. As at 31 December 2022, £12.1m of related trade receivables 
were outstanding, with extended credit terms provided to 31 March 2023.

Cash receipts since the year end amount to £2.1m (received as an early settlement) with 
£10.0m outstanding but not overdue at the time of our report. 

We consider the recoverability of trade receivables of this distributor to be a key audit matter. 
There is a critical judgement made by management in the recoverability of the balance 
outstanding, given that this was made on extended credit terms to the distributor. In addition, 
the distributor’s parent has irrevocably and unconditionally guaranteed to the group all of the 
distributor’s obligations under the distribution agreement.

Note 2.3 to the financial statements provides details of the critical accounting judgements in 
respect of the recoverability of trade receivables with the distributor.

Note 2.13 to the financial statements sets out the group’s accounting policy for trade 
receivables and note 15 to the financial statements discloses the ageing of trade receivables.

We obtained an understanding of the relevant controls over trade receivables. 

We evaluated the contract and agreement in place with the distributor to assess the extended 
terms and to assess whether there are unusual terms.

We obtained an independent confirmation from the distributor, regarding sales made in the 
financial period and the amount owing as at 31 December 2022.

We inspected credit checks performed by management, together with available public 
records regarding the financial stability of the distributor and its parent as guarantor to the 
agreement.

We obtained a breakdown of sales to the distributor in the year and reconciled the 
outstanding balance as at 31 December 2022 to the invoices raised and cash receipts in the 
year and post year-end.

We assessed the disclosure of the recoverability of trade receivables of the distributor as a 
critical judgement.

Key observations

Based on our work performed, we concur with the group’s assessment that the amount 
outstanding remains recoverable; and we consider the disclosure of this being a critical 
judgement as at 31 December 2022 and as at the date of reporting appropriate.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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6.  Our application of materiality
6.1  Materiality
We define materiality as the magnitude of misstatement in the financial statements that makes it 
probable that the economic decisions of a reasonably knowledgeable person would be changed 
or influenced. We use materiality both in planning the scope of our audit work and in evaluating 
the results of our work.

Based on our professional judgement, we determined materiality for the financial statements as a 
whole as follows:

Profit before tax adjusted for impairment  
£23.4m (2021: £32.2m)

Group materiality 
£1.5m (2020: £1.5m)

Group materiality £1.5m 

Component materiality range £0.4m to £1.4m

Audit Committee reporting threshold £0.075m

Materiality

Basis for 
determining 
materiality

Rationale for 
the benchmark 
applied

Group financial statements

Parent company financial statements

£1,500,000  
(2021: predecessor auditor £1,500,000)

£600,000  
(2021: predecessor auditor: £900,000)

6.4% of profit before tax adjusted for impairment. 
Materiality equates to 0.9% of revenue.

0.5% of net assets, capped at 40% of group 
materiality.

  Adjusted PBT

  Group materiality

In the prior year, the predecessor auditor 
determined materiality which represented 4.7% 
of profit before tax, normalised to exclude the 
impairment of intangible assets and the CMA 
provision.

Adjusted profit before tax is a key metric for the 
principal users of the financial statements as 
it derives the prediction of future share price, 
the ability to pay dividends, and is therefore of 
particular importance to both shareholders and 
potential investors. Impairment of non-current 
assets are also excluded for banking covenant 
calculations. 

In the prior year, the predecessor auditor 
determined materiality based on 0.5% of total 
assets.

The company is non-trading and operates 
primarily as a holding company. As such, 
we believe the net asset position is the most 
appropriate benchmark to use.

6.2  Performance materiality
We set performance materiality at a level lower than materiality to reduce the probability that, 
in aggregate, uncorrected and undetected misstatements exceed the materiality for the financial 
statements as a whole. 

Group financial statements

Parent company financial statements

Performance 
materiality

70% of group materiality (2021: predecessor 
auditor: 75% of group materiality)

70% of parent company materiality (2021: 
predecessor auditor: 75% of parent company 
materiality) 

Basis and 
rationale for 
determining 
performance 
materiality

In determining performance materiality, we considered the following factors: 

 › Our understanding of the group and its environment, together with changes in the business.

 ›

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The overall quality of the control environment.

The nature, size and number of uncorrected misstatements identified in the prior year by the 
predecessor auditor.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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6.  Our application of materiality continued
6.3.  Error reporting threshold
We agreed with the Audit and Risk Committee that we would report to the Committee all audit 
differences in excess of £75,000 (2021: £75,000) as well as differences below that threshold 
that, in our view, warranted reporting on qualitative grounds. We also report to the Audit and Risk 
Committee on disclosure matters that we identified when assessing the overall presentation of the 
financial statements.

Revenue

9%

9%

7.  An overview of the scope of our audit
7.1  Identification and scoping of components
Our audit scoping considered the significance of each component, including the nature of the 
group and its environment and an assessment of the risks of material misstatement across the 
group. 

Full scope audit procedures have been completed for the following components:

 › Alliance Pharma plc; 
 › Alliance Pharmaceuticals Limited; and 
 › Alliance Pharma, Inc.

Net assets

5%

A combination of specified balances and analytical procedures at a group level has been 
completed for the remaining components of the group.

Our group scoping, as defined as scope A below, results in 82% of group revenues, 81% of group 
profit before tax, and 95% of group net assets being subject to full scope audit procedures.

All of these procedures were performed by the group engagement team in the United Kingdom. 

95%

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Profit before tax

16%

3%

82%

81%

  Scope – A – Full scope components

  Scope – B – Specified balances

  Scope – C – Desktop review

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7.  An overview of the scope of our audit continued
7.2  Our consideration of the control environment
The group operates a diverse IT infrastructure. With the involvement of our IT specialists, 
we obtained an understanding of the relevant IT environment and assessed the design and 
implementation of key general IT controls.

For all in scope components we obtained an understanding of the relevant controls associated with 
the financial reporting process, key audit matters, accounting estimates and revenue recognition. 
We did not plan to rely on controls in any areas of the audit and instead adopted a fully 
substantive approach. This is due to the group being in the process of updating their controls and 
processes, specifically to improve documentary evidence of the operation of controls. 

7.3  Our consideration of climate-related risks 
The group has assessed that climate did not have a material impact on the Group’s carrying value 
of assets and liabilities at the balance sheet date. 

We assessed the climate related risk of material misstatement and concur with management’s 
assessment. With support from our climate specialists we read the related narrative in the 
annual report to consider whether it is materially consistent with the financial statements and our 
knowledge obtained in the audit. 

8.  Other information
The other information comprises the information included in the annual report other than the 
financial statements and our auditor’s report thereon. The directors are responsible for the other 
information contained within the annual report.

Our opinion on the financial statements does not cover the other information and, except to the 
extent otherwise explicitly stated in our report, we do not express any form of assurance conclusion 
thereon.

Our responsibility is to read the other information and, in doing so, consider whether the other 
information is materially inconsistent with the financial statements or our knowledge obtained in the 
course of the audit, or otherwise appears to be materially misstated.

If we identify such material inconsistencies or apparent material misstatements, we are required to 
determine whether this gives rise to a material misstatement in the financial statements themselves. 
If, based on the work we have performed, we conclude that there is a material misstatement of this 
other information, we are required to report that fact.

We have nothing to report in this regard.

9.  Responsibilities of directors
As explained more fully in the directors’ responsibilities statement, the directors are responsible 
for the preparation of the financial statements and for being satisfied that they give a true and fair 
view, and for such internal control as the directors determine is necessary to enable the preparation 
of financial statements that are free from material misstatement, whether due to fraud or error.

In preparing the financial statements, the directors are responsible for assessing the group’s and the 
parent company’s ability to continue as a going concern, disclosing as applicable, matters related 
to going concern and using the going concern basis of accounting unless the directors either 
intend to liquidate the group or the parent company or to cease operations, or have no realistic 
alternative but to do so.

10.  Auditor’s responsibilities for the audit of the financial statements
Our objectives are to obtain reasonable assurance about whether the financial statements as a 
whole are free from material misstatement, whether due to fraud or error, and to issue an auditor’s 
report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a 
guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material 
misstatement when it exists. Misstatements can arise from fraud or error and are considered 
material if, individually or in the aggregate, they could reasonably be expected to influence the 
economic decisions of users taken on the basis of these financial statements.

A further description of our responsibilities for the audit of the financial statements is located on 
the FRC’s website at: www.frc.org.uk/auditorsresponsibilities. This description forms part of our 
auditor’s report.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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11.  Extent to which the audit was considered capable of detecting irregularities, 
including fraud
Irregularities, including fraud, are instances of non-compliance with laws and regulations. We 
design procedures in line with our responsibilities, outlined above, to detect material misstatements 
in respect of irregularities, including fraud. The extent to which our procedures are capable of 
detecting irregularities, including fraud is detailed below. 

11.1.  Identifying and assessing potential risks related to irregularities
In identifying and assessing risks of material misstatement in respect of irregularities, including 
fraud and non-compliance with laws and regulations, we considered the following:

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the nature of the industry and sector, control environment and business performance including 
the design of the group’s remuneration policies, key drivers for directors’ remuneration, bonus 
levels and performance targets;
results of our enquiries of management, the directors and the audit committee about their own 
identification and assessment of the risks of irregularities; 
any matters we identified having obtained and reviewed the group’s documentation of their 
policies and procedures relating to:

 ‒ identifying, evaluating and complying with laws and regulations and whether they were 
aware of any instances of non-compliance, including the UK’s Competition and Market 
Authority’s infringement decision, as described within the financial review section of the 
annual report and note 20 of the financial statements;

 ‒ detecting and responding to the risks of fraud and whether they have knowledge of any 

actual, suspected or alleged fraud;

 ‒ the internal controls established to mitigate risks of fraud or non-compliance with laws and 

regulations

 ›

the matters discussed among the audit engagement team including tax, valuations, impairment, 
IT and forensic specialists regarding how and where fraud might occur in the financial 
statements and any potential indicators of fraud.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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As a result of these procedures, we considered the opportunities and incentives that may exist 
within the organisation for fraud and identified the greatest potential for fraud in the following 
areas:

 › Valuation of Amberen Cash Generating Unit
 ›
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Revenue recognised, for a significant distributor
Recoverability of trade receivables, with a significant distributor

In common with all audits under ISAs (UK), we are also required to perform specific procedures to 
respond to the risk of management override.

We also obtained an understanding of the legal and regulatory frameworks that the group 
operates in, focusing on provisions of those laws and regulations that had a direct effect on the 
determination of material amounts and disclosures in the financial statements. The key laws and 
regulations we considered in this context included the AIM rules, UK Companies Act, and tax 
legislation.

In addition, we considered provisions of other laws and regulations that do not have a direct effect 
on the financial statements but compliance with which may be fundamental to the group’s ability to 
operate or to avoid a material penalty. This includes the group’s ability to obtain relevant approvals 
for the sale of products.

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

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I N D E P E N D E N T   A U D I T O R ’ S   R E P O R T   C O N T I N U E D

11.  Extent to which the audit was considered capable of detecting irregularities, 
including fraud continued
11.2.  Audit response to risks identified
As a result of performing the above, we identified the valuation of Amberen Cash Generating Unit 
and the recoverability of trade receivables, with a significant distributor as key audit matters related 
to the potential risk of fraud. The key audit matters section of our report explains the matters in more 
detail and also describes the specific procedures we performed in response to those key audit 
matters. 

In addition to the above, our procedures to respond to risks identified included the following:

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reviewing the financial statement disclosures and testing to supporting documentation to assess 
compliance with provisions of relevant laws and regulations described as having a direct effect 
on the financial statements;
enquiring of management, the audit committee and in-house/external legal counsel 
concerning actual and potential litigation and claims;
performing analytical procedures to identify any unusual or unexpected relationships that may 
indicate risks of material misstatement due to fraud;
reading minutes of meetings of those charged with governance, and reviewing 
correspondence with HMRC;
engaging with fraud specialists to consider the risk of fraud within the group and to establish 
appropriate and suitable substantive audit procedures; 
in relation to the potential fraud risk in revenue, we obtained a confirmation letter from the 
significant distributor confirming value of goods purchased in the 12 months ended 31 
December 2022; obtained a breakdown of sales to the distributor in the year and traced these 
through to signed delivery notes and cash receipts in the year and post year-end; and
in addressing the risk of fraud through management override of controls, testing the 
appropriateness of journal entries and other adjustments; assessing whether the judgements 
made in making accounting estimates are indicative of a potential bias; and evaluating the 
business rationale of any significant transactions that are unusual or outside the normal course 
of business.

We also communicated relevant identified laws and regulations and potential fraud risks to all 
engagement team members including internal specialists, and remained alert to any indications of 
fraud or non-compliance with laws and regulations throughout the audit.

REPORT ON OTHER LEGAL AND REGULATORY REQUIREMENTS
12.  Opinions on other matters prescribed by the Companies Act 2006
In our opinion, based on the work undertaken in the course of the audit:

 ›

 ›

the information given in the strategic report and the directors’ report for the financial year for 
which the financial statements are prepared is consistent with the financial statements; and
the strategic report and the directors’ report have been prepared in accordance with 
applicable legal requirements.

In the light of the knowledge and understanding of the group and the parent company and their 
environment obtained in the course of the audit, we have not identified any material misstatements 
in the strategic report or the directors’ report.

13.  Opinion on other matter prescribed by our engagement letter
In our opinion the part of the Directors’ Remuneration Report to be audited has been properly 
prepared in accordance with the provisions of the Companies Act 2006 that would have applied 
were the company a quoted company.

14.  Matters on which we are required to report by exception
14.1.  Adequacy of explanations received and accounting records
Under the Companies Act 2006 we are required to report to you if, in our opinion:

 › we have not received all the information and explanations we require for our audit; or
 ›

adequate accounting records have not been kept by the parent company, or returns adequate 
for our audit have not been received from branches not visited by us; or
the parent company financial statements are not in agreement with the accounting records  
and returns.

 ›

We have nothing to report in respect of these matters.

14.2.  Directors’ remuneration
Under the Companies Act 2006 we are also required to report if in our opinion certain disclosures 
of directors’ remuneration have not been made.

We have nothing to report in respect of this matter.

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101

I N D E P E N D E N T   A U D I T O R ’ S   R E P O R T   C O N T I N U E D

15.  Use of our report
This report is made solely to the company’s members, as a body, in accordance with Chapter 3 of 
Part 16 of the Companies Act 2006. Our audit work has been undertaken so that we might state 
to the company’s members those matters we are required to state to them in an auditor’s report 
and for no other purpose. To the fullest extent permitted by law, we do not accept or assume 
responsibility to anyone other than the company and the company’s members as a body, for our 
audit work, for this report, or for the opinions we have formed.

Andrew Wright, FCA 

(Senior statutory auditor) 
For and on behalf of Deloitte LLP 
Statutory Auditor 
Bristol, United Kingdom

21 March 2023

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

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102

All of the activities of the Group are classed  
as continuing.

The accompanying accounting policies  
and notes form an integral part of these 
financial statements.

Financial Statements
Independent Auditor’s Report 

93

Consolidated Income Statement 

102

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

103

104

105

106

107

108

109

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C O N S O L I D A T E D   I N C O M E   S T A T E M E N T

Revenue

Cost of sales

Gross profit

Operating expenses

Administration and marketing expenses

Amortisation of intangible assets

Impairment of goodwill and  
intangible assets

CMA provision

Note

3,31

5

5, 11

5

20

Share-based employee remuneration

7, 24

Operating profit 

Finance costs

Interest payable and similar charges

Finance income

Profit before taxation

Taxation

Profit for the period attributable to  
equity shareholders

Earnings per share

Basic (pence)

Diluted (pence)

6

6

4

8

10

10

Year ended 31 December 2022

Year ended 31 December 2021

Underlying
£000s

167,416 

(65,733)

101,683 

Non-underlying
£000s 
(Note 5)

 –   

–

 –   

Total
£000s

167,416 

(65,733)

Underlying
£000s

163,207

(53,757)

101,683 

109,450

(63,955)

(1,964)

369 

(63,586)

(7,238)

(9,202)

(60,202)

(1,362)

 –   

–

(92)

(18,234)

(18,234)

–

 –   

–

(92)

35,672 

(25,103)

10,569

(5,433)

72 

(5,361)

30,311 

(7,234)

–

 –   

 –   

(25,103)

2,962 

(5,433)

72 

(5,361)

5,208

(4,272)

–

–

(2,250)

45,636

(3,646)

228

(3,418)

42,218

(8,033)

Non-underlying

£000s 
(Note 5)

–

–

–

(2,843)

(7,168)

(6,150)

(7,900)

–

(24,061)

–

–

–

(24,061)

(2,805)

Total
£000s

163,207

(53,757)

109,450

(63,045)

(8,530)

(6,150)

(7,900)

(2,250)

21,575

(3,646)

228

(3,418)

18,157

(10,838)

23,077 

(22,141)

936 

34,185

(26,866)

7,319

4.28 

4.23 

0.17 

0.17

6.39

6.30

1.37

1.35

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103

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

C O N S O L I D A T E D   S T A T E M E N T   O F   C O M P R E H E N S I V E   I N C O M E

Profit for the year

Other comprehensive income

Items that may be reclassified to profit or loss

Foreign exchange translation differences (gross)

Foreign exchange translation differences (deferred tax)

Foreign exchange forward contracts – cash flow hedge (gross)

Foreign exchange forward contracts – cash flow hedge (deferred tax)

Total comprehensive income for the year

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

936

7,319

16,438

(3,589)

111

(28)

13,868

586

50

(255)

64

7,764

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

For more information visit  
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C O N S O L I D A T E D   B A L A N C E   S H E E T

Assets

Non-current assets

Goodwill and intangible assets

Property, plant and equipment

Deferred tax asset

Derivative financial instruments

Other non-current assets

Current assets

Inventories

Trade and other receivables

Derivative financial instruments

Cash and cash equivalents 

Total assets

Equity

Ordinary share capital

Share premium account

Share option reserve

Other reserve

Cash flow hedging reserve

Translation reserve

Retained earnings

Total equity

11

12

22

21

14

15

21

16

23

Note

31 December 2022
£000s

31 December 2021
£000s

Note

31 December 2022
£000s

31 December 2021
£000s

421,630

413,744

Loans and borrowings

Liabilities

Non-current liabilities

5,578 

4,117 

17 

588 

4,826

3,526

–

371

431,930

422,467

24,286 

49,324 

157 

31,714 

105,481 

537,411

5,400 

151,650 

10,141 

(329)

131 

12,430 

108,238

287,661

21,075

30,821

64

29,061

81,021

503,488

5,382

151,328

10,058

(329)

48

(419)

116,418

282,486

Other liabilities

Deferred tax liability

Current liabilities

Corporation tax

Trade and other payables 

Provisions

Total liabilities

Total equity and liabilities

18

19

22

17

20

133,744 

3,415 

65,569 

202,728 

2,984

35,616 

8,422 

47,022 

249,750

537,411

116,060

2,637

61,728

180,425

1,178

29,930

9,469

40,577

221,002

503,488

The financial statements were approved by the Board of Directors on 20 March 2023.

Peter Butterfield 
Director 

Andrew Franklin
Director

The accompanying accounting policies and notes form an integral part of these 
financial statements. 

Company number 04241478

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105

C O M P A N Y   B A L A N C E   S H E E T

Assets

Non-current assets

Investment and loans to subsidiaries

Current assets

Trade and other receivables

Cash and cash equivalents

Total assets

Equity

Ordinary share capital

Share premium account

Share option reserve

Retained earnings

Total equity

Liabilities

Current liabilities

Trade and other payables 

Corporation tax

Total liabilities

Note

31 December 2022
 £000s

31 December 2021
 £000s

The Company’s profit for the year was £5,429,000 (2021: £6,756,000).

As permitted by section 408 of the Companies Act 2006, no separate Income Statement  
is presented in respect of the Parent Company.

The financial statements were approved by the Board of Directors on 20 March 2023.

Peter Butterfield 
Director 

Andrew Franklin
Director

The accompanying accounting policies and notes form an integral part of these 
financial statements. 

Company number 04241478

13

15

16

23

17

197,253

199,348

93 

50 

143 

39

141

180

197,396 

199,528

5,400 

151,650 

10,214 

29,377 

196,641 

755

–

755

5,382

151,328

8,962

33,064

198,736

368

424

792

Total equity and liabilities

197,396

199,528

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

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C O N S O L I D A T E D   S T A T E M E N T   O F   C H A N G E S   I N   E Q U I T Y

Balance 1 January 2021

Issue of shares

Dividend paid

Share options charge (including deferred tax)

Transactions with owners

Profit for the year

Other comprehensive income

Foreign exchange forward contracts – cash flow hedge (net of deferred tax)

Foreign exchange translation differences (net of deferred tax)

Total comprehensive income for the year

Balance - 31 December 2021

Balance 1 January 2022

Issue of shares

Dividend paid

Share options charge (including deferred tax)

Transactions with owners

Profit for the year

Other comprehensive income

Foreign exchange forward contracts – cash flow hedge (net of deferred tax)

Foreign exchange translation differences (net of deferred tax)

Total comprehensive income for the year

Balance - 31 December 2022

Ordinary share 
capital
£000s

Share premium 
account 
£000s

 Other reserve
£000s

Cash flow hedging 
reserve
£000s

Translation reserve 
£000s

Share option 
reserve
£000s

Retained earnings 
£000s

Total  
equity
£000s

5,329

150,645

(329)

239

(1,055)

8,426

117,703

280,958

53

–

–

53

–

–

–

–

683

–

–

683

–

–

–

–

–

–

–

–

–

–

–

–

5,382

151,328

(329)

–

–

–

–

–

(191)

–

(191)

48

–

–

–

–

–

–

636

636

–

–

1,632

1,632

–

–

–

–

–

(8,604)

–

(8,604)

7,319

–

–

736

(8,604)

1,632

(6,236)

7,319

(191)

636

7,319

7,764

(419)

10,058

116,418

282,486

5,382 

151,328 

(329)

48 

(419)

10,058 

116,418 

282,486 

18 

 –   

 –   

18 

–

 –   

 –   

 –   

322 

 –   

 –   

322 

–

 –   

 –   

 –   

 –  

 –   

 –   

 –   

–

 –   

 –   

 –   

5,400 

151,650 

(329)

 –   

 –   

 –   

 –   

–

83 

 –   

83 

131 

 –   

 –   

 –   

–

–

–

12,849 

12,849

 –   

 –   

83 

83 

–

 –   

 –   

 –   

 –   

340 

(9,116)

(9,116)

 –   

83 

(9,116)

(8,693)

936

936

–

 –   

83 

12,849 

936

13,868

12,430 

10,141 

108,238

287,661

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

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C O M P A N Y   S T A T E M E N T   O F   C H A N G E S   I N   E Q U I T Y

Balance 1 January 2021

Issue of shares

Dividend paid

Share options charge (including deferred tax)

Transactions with owners

Profit for the period and total comprehensive income

Balance 1 January 2022

Issue of shares

Dividend paid

Share options charge (including deferred tax)

Transactions with owners

Profit for the period and total comprehensive income

Ordinary share capital
£000s

Share premium account
£000s 

Share option reserve
£000s

Retained earnings
£000s 

5,329

150,645

7,955

53

–

–

53

–

683

–

–

683

–

18 

–

–

18 

–

322

–

–

322 

–

–

–

1,007

1,007

–

8,962

34,912

–

(8,604)

–

(8,604)

6,756

33,064

Total equity
£000s

198,841

736

(8,604)

1,007

(6,862)

6,756

198,736

–

–

1,252 

1,252 

–

10,214 

–

(9,116)

–

(9,116)

5,429 

29,377 

340 

(9,116)

1,252 

(7,524)

5,429

196,641 

5,382 

151,328 

8,962 

33,064 

198,736 

Balance 31 December 2021

5,382

151,328

Balance 31 December 2022

5,400 

151,650 

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

Notes to the Financial Statements 

93

102

103

104

105

106

107

108

109

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C O N S O L I D A T E D   A N D   C O M P A N Y   C A S H   F L O W   S T A T E M E N T S

Cash flows from operating activities
Cash generated from operations
Tax paid
Cash flows from/(used in) operating activities
Investing activities

Dividend received

Acquisitions

Purchase of intangible assets

Purchase of property, plant and equipment

Proceeds from reimbursement of property costs 

Contribution from subsidiary
Proceeds from disposal of intangibles 
Net cash (used in)/from investing activities
Financing activities
Interest paid and similar charges 
Capital lease payments 
Proceeds from exercise of share options
Dividend paid

Proceeds from borrowings
Repayment of borrowings
Net cash provided by/(used in) financing activities
Net movement in cash and cash equivalents
Cash and cash equivalents at 1 January
Exchange (gains)/losses on cash and cash equivalents
Cash and cash equivalents at 31 December

Group

Company

Year ended
31 December 2022
£000s

Year ended
31 December 2021
£000s

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

24,929 
(3,957)
20,972 

–

(16,618)

(249)

(358)

200
–
–
(17,025)

(4,804)
(961)
341 
(9,116)

14,925 
(1,261)
(876)
3,071 
29,061 
(418)
31,714 

44,919
(6,260)
38,659

–

183

(4,006)

(1,526)

–
–
750
(4,599)

(2,965)
(924)
736
(8,604)

–
(22,587)
(34,344)
(284)
28,898
447
29,061

(1,385)
–
(1,385)

–

–

–

–

–
10,069
–
10,069

–
–
341
(9,116)

–
–
(8,775)
(91)
141
–
50

(961)
–
(961)

2,600

–

–

–

–
6,073
–
8,673

–
–
736
(8,604)

–
–
(7,868)
(156)
297
–
141

Note

25

11

11

12

12

13

9

21

21

16

In the Company cash flow statement, the 
‘contribution from subsidiary’ cash flows have 
been reclassified from financing activities to 
investing activities. This reclassification has 
been made for both the year ended  
31 December 2022 and the year ended 
31 December 2021. In addition, no tax was 
paid by the Company in the year ended  
31 December 2021 and as such, the 
‘tax paid’ cash flows of £1.5m, which 
did not reflect a cash outflow, have been 
removed from the cash flow statement. The 
corresponding non-cash movement was 
included within ‘contribution from subsidiary’ 
which has also been reduced by the  
same amount.

The accompanying accounting policies  
and notes form an integral part of these 
financial statements. 

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109

N O T E S   T O   T H E   F I N A N C I A L   S T A T E M E N T S

1. General information
Alliance Pharma plc (‘the Company’) and its subsidiaries 
(together ‘the Group’) acquire, market and distribute consumer 
healthcare products and prescription medicines. The Company 
is a public limited company, limited by shares, registered, 
incorporated and domiciled in England and Wales in the UK. 
The address of its registered office is Avonbridge House, Bath 
Road, Chippenham, Wiltshire, SN15 2BB. The Company is listed 
on the AIM stock exchange.

These consolidated financial statements have been approved for 
issue by the Board of Directors on 20 March 2023.

2. Summary of significant  
accounting policies
The principal accounting policies applied in the preparation 
of these consolidated financial statements are set out below. 
These policies have been consistently applied to all the periods 
presented, unless otherwise stated.

2.1 Basis of preparation
These financial statements have been prepared and approved 
by the Directors in accordance with UK-adopted international 
accounting standards (‘UK-adopted IFRS’).

The financial statements have been prepared under the historical 
cost convention, with the exception of derivatives which are 
included at fair value. 

A number of amended standards became applicable for the 
current reporting period. The application of these amendments 
has not had any material impact on the disclosures, net assets or 
results of the Group.

2.2 Consolidation
The Group financial statements consolidate those of the 
Company and its subsidiaries (together referred to as ‘the 
Group’) and equity account the Group’s interest in joint ventures. 
The Parent Company financial statements present information 
about the Company as a separate entity and not about 
the Group.

Subsidiaries
Subsidiaries are entities controlled by the Group. The Group 
controls an entity when it is exposed to, or has rights to, variable 
returns from its involvement with the entity and has the ability to 
affect those returns through its power over the entity. In assessing 
control, the Group takes into consideration potential voting rights. 
The acquisition date is the date on which control is transferred to 
the acquirer. The financial statements of subsidiaries are included 
in the consolidated financial statements from the date that control 
commences until the date that control ceases.

Joint ventures
An entity is treated as a joint venture where the Group has rights 
to the net assets of the arrangement, rather than rights to its assets 
and obligations for its liabilities. Joint ventures are accounted for 
using the equity method (‘equity accounted investees’) and are 
initially recognised at cost. The consolidated financial statements 
include the Group’s share of the total comprehensive income 
and equity movements of equity accounted investees, from 
the date that joint control commences until the date that joint 
control ceases.

Transactions eliminated on consolidation
Intra-Group balances and transactions, and any unrealised 
income and expenses arising from intra-Group transactions, 
are eliminated. 

2.3 Judgements and estimates
The preparation of the consolidated financial statements requires 
the Directors to make judgements, estimates and assumptions 
that affect the application of policies and reported amounts of 
assets and liabilities, income and expenses. The estimates and 
associated assumptions are based on historical experience 
and various other factors that are believed to be reasonable 
under the relevant circumstances. Actual results may differ from 
these estimates. 

The estimates and underlying assumptions are reviewed by the 
Directors on an ongoing basis. 

Judgements
The following are the critical judgements, apart from those 
involving estimates (which are dealt with separately below), that 
the Directors have made in the process of applying the Group’s 
accounting policies that have the most significant effect on the 
amounts recognised in the Group’s financial statements. 

These are as follows:

 ›

Recoverability of trade receivables with a significant 
distributor. 

 › Assessment of cloud-based software costs in relation to the 

 ›

Group’s cloud hosted ERP system.
Identification and presentation of  
non-underlying items (note 5).

 › Assessment of the Infringement Decision announced by the 
UK’s Competition and Markets Authority (‘CMA’) (note 20).

Recoverability of trade receivables with a significant 
distributor 
As at 31 December 2022, £12.1m of related trade 
receivables were outstanding with a significant distributor, 
with extended credit terms provided to 31 March 2023.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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2. Summary of significant accounting policies 
continued
2.3 Judgements and estimates continued
Cash receipts since the year end amount to £2.1m (received 
as an early settlement) with £10.0m outstanding but not 
overdue at the date of this report.

Having considered these factors the Group concluded that 
it does have substantive control over the ERP system and has 
therefore recognised it as an intangible asset in line with the 
guidance under IAS 38. In the prior year, had the Group 
concluded that it does not have control, a proportion of the costs 
would have been expensed in the Income Statement.

The recoverability of the balance outstanding is considered 
a critical judgement, given the size of the balance. The 
distributor has no history of bad debt, and the distributor’s 
parent has irrevocably and unconditionally guaranteed to the 
Group all of the distributor’s obligations under the distribution 
agreement. Having considered these factors, the Group 
concludes that the amount outstanding remains recoverable.

Intangible assets – cloud-based software costs 
The determination of whether a cloud-based software 
arrangement represents a pure Software as a Service 
solution, or a right to take possession of, and to use, the 
software requires judgement. 

In the year ended 31 December 2021, in light of the IFRIC 
agenda decision regarding cloud-based software, the Group 
reviewed its service agreements in respect of its cloud-based 
ERP system and considered several factors to conclude on the 
appropriate accounting treatment. These factors include the 
nature and key terms of licence arrangements, ownership of 
intellectual property rights, ability to restrict access to systems 
and the feasibility of removing software applications from the 
cloud environment and running them within the Group’s own IT 
environment instead, taking into account the associated costs and 
potential change in functionality. 

Identification and presentation of  
non-underlying items
In 2020 the Group updated its classification policy for non-
underlying items (note 5). Following the update all amortisation 
and impairment charges for acquired intangible assets are 
included as non-underlying items, in line with the majority of 
peer companies of the Group. Significant restructuring costs (for 
example, relating to office or business closures), the CMA provision 
and the revaluation of deferred tax balances following substantial 
tax legislation changes are also included as non-underlying items.

The Directors believe that this classification of underlying 
and non-underlying items, when considered together with 
total statutory results, provides investors, analysts and other 
stakeholders with helpful complementary information to 
understand better the financial performance and position 
of the Group from period to period, and allows the Group’s 
performance to be more easily compared against the majority 
of its peer companies. These measures are also used by 
management for planning and reporting purposes. They may not 
be directly comparable with similarly described measures used 
by other companies.

Estimates
IAS 1 requires the disclosure of assumptions and estimates at the 
end of the current reporting period that have a significant risk 
of resulting in a material adjustment to the carrying amounts of 
assets and liabilities within the next financial year.

The Directors consider these estimates to be as follows: 

 › Key assumptions used in discounted cash flow projections for 
impairment testing of certain intangible assets (note 11).
 › Determination of the useful economic lives for the intangible 

brand and distribution rights assets (note 11).

2.4 Revenue recognition
Identification of performance obligations
Revenue comprises consideration received or receivable for the 
sale of goods in the ordinary course of the Group’s activities, 
namely the distribution of pharmaceutical products. The Group 
has assessed the performance obligations as being each unit of 
good sold by the Group. 

The Group receives royalties in relation to certain agreements 
with distributors in exchange for the licensed use of intellectual 
property and trademarks owned by the Group, which are 
generally based on sales volumes. The Group also receives 
product margin generated by third parties on its behalf under 
certain transitional arrangements. The Group has assessed the 
performance obligations as being each unit of good sold by the 
third parties. 

Transaction price
The transaction price for each performance obligation comprises 
the stand-alone selling price for the product excluding value-
added tax and net of rebates and discounts. Intra-Group sales 
are eliminated in the consolidated financial statements.

Royalty income and the deductions relating to rebates and 
discounts are based on the Group’s contractual obligations. 
Certain of the rebate arrangements also include elements of 
variable consideration. The Group does not consider these 
elements to be significant; however, an estimate of variable 
consideration is included where appropriate. The IFRS 15 
exemption from estimating variable consideration has been 
applied to the Group’s sales-based royalties.

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

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2. Summary of significant accounting policies 
continued
2.4 Revenue recognition continued
The Group has considered whether it is an ‘agent’ or ‘principal’ 
under IFRS 15 for each commercial arrangement and accounted 
for these accordingly. The Group is considered the ‘principal’ 
for all key commercial relationships relating to sale of goods, 
except the relationship with certain supply partners as described 
in full under ‘Specific revenue streams’. This is because the Group 
controls each specified good before transfer to customers.

Where consideration is payable to a customer, this is evaluated 
by the Group to determine whether the amount represents a 
reduction of the transaction price, a payment for distinct goods 
or services or a combination of the two. The fair value of the 
good or service is also evaluated to assess whether the payment 
should be accounted for as a payment to suppliers or a reduction 
in transaction price.

Timing of recognition
Under IFRS 15 an entity recognises revenue when it satisfies a 
performance obligation by transferring a good to a customer. An 
entity transfers a good to a customer when the customer obtains 
control of that good. Control may be transferred either at a point 
in time or over time. For the Group, revenue is recognised at a 
point in time when customers have control of the sold goods, or 
on an appropriate basis where royalty or other arrangements 
are in place with third parties. To determine the point in time 
control is transferred for sale of goods the Group considers all 
relevant indicators. Revenue is recognised net of a provision for 
the expected level of returns.

Specific revenue streams
The Group has the following recognition policies for different 
commercial arrangements: 

(i) 

 Pharmaceutical product sales – ex-works terms: Recognition 
at a point in time when each unit of pharmaceutical product 
is available to the customer for collection. At this point in time 
the customer has an obligation to pay for the goods, legal 
title and significant risks and rewards of ownership.

(ii)   Pharmaceutical product sales – delivery terms and delivery 
at place: Recognition at a point in time when each unit 
of pharmaceutical product is delivered to the customer 
or reaches the designated place. At this point in time the 
customer has an obligation to pay for the goods, legal title 
and significant risks and rewards of ownership. This revenue 
recognition policy covers the cross border e-commerce 
stream as referred to in the Strategic Report. 

(iii)  Pharmaceutical product royalties receivable: Recognition at 
a point in time when the third party makes pharmaceutical 
product sales subject to a royalty agreement with the Group. 

(iv)  Pharmaceutical product rebates, discounts and payments to 
customers: Recognition as a deduction from revenue when 
the third party makes pharmaceutical product sales subject to 
a rebate agreement with the Group or when sales are made 
in the scope of the VPAS Voluntary Scheme. 

 VPAS applies to branded, licensed medicines which are 
available on NHS prescription. Under the scheme, a fixed 
percentage of measured sales is due to the Department of 
Health and Social Care and the rebate is calculated and 
paid on a quarterly basis. For medium-sized companies, the 
VPAS scheme includes an exemption where total measured 
sales are less than £5.0m per year. As the Group’s total 
measured sales in 2022 were under this threshold, the Group 
was exempt from any VPAS payments and, as a result, no 
amounts were deducted from revenue (2021: no deduction).

 For transactions with variable consideration, such 
as coupons, this is recognised at the point of sale to 
the customer. 

 Payments to customers are accounted for as a reduction of 
revenue unless they are linked to a distinct service, in which 
case they are classified as an operating expense. 

(v)   Pharmaceutical product transitional agreements: Recognition 
of a point in time when the third party makes pharmaceutical 
product sales subject to a transitional agreement with 
the Group. 

 The amounts recognised in statutory revenue represent the 
product margin generated by the third party on behalf of the 
Group. Related transitional agreement fees are recognised 
within administrative expenses. 

 This is relevant to Nizoral™ (note 31) where the Group 
has transitional agreements with certain supply partners. 
Under the terms of the agreements, the Group receives the 
benefit of the net profit on sales of Nizoral™ from the date 
of acquisition up until the product licences in the Asia-Pacific 
territories transfer to Alliance. The Group has determined it is 
an ‘agent’ in these relationships as it does not control the sale 
of goods to third party customers. 

The Group does not consider that judgements made in 
evaluating when customers obtain control of a promised good 
have significantly influenced the timing of revenue recognition in 
the year.

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Company Overview

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

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For more information visit  
alliancepharmaceuticals.com

2. Summary of significant accounting policies 
continued
2.5 Foreign currency
The consolidated financial statements are presented in 
Sterling, which is the presentational currency of the Group 
and the functional currency of the Company. Foreign currency 
transactions by Group companies are booked at the exchange 
rate ruling on the date of the transaction. Foreign currency 
monetary assets and liabilities are retranslated into Sterling at 
the rate of exchange ruling at the balance sheet date. Foreign 
exchange differences arising on translation are recognised 
in the Income Statement, except for differences arising on the 
retranslation of a financial liability designated as a hedge of 
the net investment in a foreign operation that is effective, or 
qualifying cash flow hedges, which are recognised directly in 
other comprehensive income.

The assets and liabilities of foreign operations, including 
goodwill and fair value adjustments arising on consolidation, 
are translated to the Group’s presentational currency, Sterling, 
at foreign exchange rates ruling at the balance sheet date. The 
revenues and expenses of foreign operations are translated 
at an average rate for the year where this rate approximates 
to the foreign exchange rates ruling at the dates of the 
transactions. Exchange differences arising from translation 
of foreign operations are reported in other comprehensive 
income and accumulated in the translation reserve. Foreign 
currency differences arising on the retranslation of a hedge of 
a net investment in a foreign operation are reported in other 
comprehensive income and accumulated in the translation 
reserve, to the extent that the hedge is effective.

2.6 Operating segments
Operating segments are reported in a manner consistent with 
the internal reporting provided to the Group’s Chief Operating 
Decision Maker (‘CODM’). The Group’s Board of Directors 
(‘the Board’) is the Group’s Chief Operating Decision Maker, 
as defined by IFRS 8, and all significant operating decisions are 
taken by the Board. 

2.7 Property, plant and equipment
Computer equipment, fixtures, fittings and equipment, plant 
and machinery and motor vehicles are stated at the cost of 
purchase less any provisions for depreciation and impairment. 
Depreciation of an asset starts when the asset is available for use. 
The rates generally applicable are:

Computer equipment  
20% – 33.3% per annum, straight line

Fixtures, fittings and equipment  
20% – 25% per annum, straight line

Plant and machinery  
20% – 25% per annum, straight line

2.8 Leases
At inception of a contract, the Group assesses whether a contract 
is, or contains, a lease. A contract is, or contains, a lease if the 
contract conveys the right to control the use of an identified asset 
for a period of time in exchange for consideration. 

Leases are recognised as a right-of-use asset and a 
corresponding liability at the date at which the leased asset is 
available for use by the Group. Each lease payment is allocated 
between the liability and finance cost. The finance cost is 
charged to profit or loss over the lease period so as to produce 
a constant periodic rate of interest on the remaining balance of 
the liability for each period. The right-of-use asset is depreciated 

over the shorter of the asset’s useful life and the lease term on a 
straight-line basis.

Assets and liabilities arising from a lease are initially measured 
on a present value basis. The lease payments are discounted 
using the Group’s incremental borrowing rate.

Payments associated with short-term leases and leases of 
low-value assets are recognised on a straight-line basis as an 
expense in the Income Statement. Short-term leases are leases 
with a lease term of 12 months or less. Low-value assets comprise 
IT equipment.

2.9 Intangible assets and goodwill
Goodwill
Goodwill is stated at cost less any accumulated impairment 
losses. Goodwill is allocated to cash-generating units (‘CGUs’)
and is not amortised but is tested annually for impairment. 

Acquired intangible assets
(i)  Brands
Separately acquired brands are shown at cost less accumulated 
amortisation and impairment. Brands acquired as part of 
a business combination are recognised at fair value at the 
acquisition date, where they are separately identifiable. Brands 
are amortised over their useful economic life, except when their 
life is determined as being indefinite.

Applying indefinite lives to certain acquired brands is 
appropriate due to the stable long-term nature of the business 
and the enduring nature of the brands. Indefinite life brands are 
tested at least annually for impairment.

A review of the useful economic life of brands is performed 
annually, to ensure that these lives are still appropriate. If a brand 
is considered to have a finite life, its carrying value is amortised 
over that period.

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

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2. Summary of significant accounting policies 
continued
2.9 Intangible assets and goodwill continued 
(ii)  Patents
Where an acquired intangible asset includes a definite period 
of patent protection and the value attributed to the patent is 
considered material, the Group has accounted for the value 
of the patent separate to the underlying brand. The patent is 
amortised over the period to patent expiry.

(iii)  Distribution rights
Payments made in respect of product registration and distribution 
rights are capitalised where the rights comply with the above 
requirements for recognition of acquired brands. If the 
registration or distribution rights are for a defined time period, the 
intangible asset is amortised over that period. If no time period 
is defined, the intangible asset is treated in the same way as 
acquired brands with an indefinite life. If the licence period can 
be extended the useful life of the intangible asset shall include the 
renewal period only if there is evidence to support renewal by 
the entity without disproportionate cost.

(iv) Computer software
Computer software comprises software purchased from third 
parties as well as the cost of internally developed software. 
Computer software licences are capitalised on the basis of 
the costs incurred to acquire and bring into use the specific 
software. Costs that are directly associated with the production 
of identifiable and unique software products controlled by the 
Group, and are probable of producing future economic benefits, 
are recognised as intangible assets. Direct costs of software 
development include employee costs and directly attributable 
overheads. Software integral to an item of hardware equipment 
is classified as property, plant and equipment. Costs associated 
with maintaining software programs are recognised as an 

expense when they are incurred. Amortisation is charged to the 
Income Statement on a straight-line basis over the estimated 
useful life from the date the software is available for use, 
generally eight years.

Development costs

Research expenditure is charged to the Income Statement in 
the period in which it is incurred. Development expenditure is 
capitalised when it can be reliably measured and the project it 
is attributable to is separately identifiable, technically feasible, 
demonstrates future economic benefit, and will be used or sold 
by the Group once completed. 

The capitalised cost is amortised over the period during which the 
Group is expected to benefit and begins when the asset is ready 
for use. 

Development costs are reviewed at least annually for impairment 
by assessing the recoverable amount of each cash-generating 
unit, to which the development costs relate. 

The recoverable amount is the higher of fair value less costs to sell 
and value in use. Development costs not meeting the recognition 
criteria are expensed as incurred.

Impairment
The carrying amounts of the Group’s non-financial assets are 
reviewed at each reporting date to determine whether there 
is any indication of impairment. For intangible assets with 
an indefinite life, assets with a finite life that show indicators 
of impairment, and goodwill this includes estimation of the 
recoverable amount.

The recoverable amount of an asset or cash-generating unit is 
the greater of its value in use and its fair value less costs to sell. 
In assessing value in use, the estimated future cash flows are 

discounted to their present value using a discount rate that reflects 
current market assessments of the time value of money and the 
risks specific to the asset. For the purpose of impairment testing, 
assets that cannot be tested individually are grouped together 
into the smallest group of assets that generates cash inflows from 
continuing use that are largely independent of the cash inflows of 
other assets or groups of assets (the ‘cash-generating unit’). The 
Directors have determined that the cash-generating units are at 
product-group level.

The goodwill acquired in a business combination, for the purpose 
of impairment testing, is allocated to cash-generating units, or 
(‘CGU’). For the purposes of goodwill impairment testing, CGUs 
to which goodwill has been allocated are aggregated so that 
the level at which impairment is tested reflects the lowest level 
at which goodwill is monitored for internal reporting purposes. 
Goodwill acquired in a business combination is allocated to 
groups of CGUs that are expected to benefit from the synergies 
of the combination.

An impairment loss is recognised if the carrying amount of an 
asset or its CGU exceeds its estimated recoverable amount. 
Impairment losses are recognised in profit or loss. Impairment 
losses recognised in respect of CGUs are allocated first to reduce 
the carrying amount of any goodwill allocated to the units, and 
then to reduce the carrying amounts of the other assets in the unit 
(group of units) on a pro rata basis.

An impairment loss in respect of goodwill is not reversed. In 
respect of other assets, impairment losses recognised in prior 
periods are assessed at each reporting date for any indications 
that the loss has decreased or no longer exists. An impairment 
loss is reversed only to the extent that the asset’s carrying amount 
does not exceed the carrying amount that would have been 
determined, net of depreciation or amortisation, if no impairment 
loss had been recognised.

Alliance Pharma plc Annual Report and Accounts 2022

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114

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

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2. Summary of significant accounting policies 
continued
2.10 Inventories
Inventories are included at the lower of cost, less any provision 
for impairment, or net realisable value. Inventory cost for the 
Group is determined on a first-in-first-out basis. Inventory 
provisions have been made for slow-moving and obsolete stock. 
These provisions are estimates and the actual costs and timing of 
future cash flows are dependent on future events. The difference 
between expectations and the actual future liability will be 
accounted for in the period when such determination is made.

2.11 Taxation
Tax on the profit or loss for the year comprises current and 
deferred tax. Tax is recognised in the Income Statement except 
to the extent that it relates to items recognised directly in equity, in 
which case it is recognised in equity.

Current tax is the expected tax payable or receivable on the 
taxable income or loss for the year, using tax rates enacted 
or substantively enacted at the balance sheet date, and any 
adjustment to tax payable in respect of previous years.

Deferred tax is provided on temporary differences between the 
carrying amounts of assets and liabilities for financial reporting 
purposes and the amounts used for taxation purposes. The 
following temporary differences are not provided for: the 
initial recognition of goodwill; the initial recognition of assets 
or liabilities that affect neither accounting nor taxable profit 
other than in a business combination; and differences relating 
to investment and loans to subsidiaries to the extent that they 
will probably not reverse in the foreseeable future. The amount 
of deferred tax provided is based on the expected manner of 
realisation or settlement of the carrying amount of assets and 
liabilities, using tax rates enacted or substantively enacted at the 
balance sheet date.

Alliance Pharma plc Annual Report and Accounts 2022

A deferred tax asset is recognised only to the extent that it is 
probable that future taxable profits will be available against 
which the temporary difference can be utilised. 

2.12 Derivative financial instruments and  
hedging activities
The Group holds derivative financial instruments to hedge its 
foreign currency risk exposures. Derivatives are initially measured 
at fair value. Subsequent to initial recognition, derivatives are 
measured at fair value, and changes therein are recognised in 
profit or loss unless designated as cash flow hedges.

The Group designates certain derivatives as hedging instruments 
to hedge the variability in cash flows associated with highly 
probable forecast transactions arising from changes in foreign 
exchange rates. 

At inception of designated hedging relationships, the Group 
documents the risk management objective and strategy for 
undertaking the hedge. The Group also documents the economic 
relationship between the hedged item and the hedging 
instrument, including whether the changes in cash flows of the 
hedged item and hedging instrument are expected to offset 
each other.

Cash flow hedges
When a derivative is designated as a cash flow hedging 
instrument, the effective portion of changes in the fair value of 
the derivative is recognised in other comprehensive income and 
accumulated in the cash flow hedging reserve. The effective 
portion of changes in the fair value of the derivative that is 
recognised in other comprehensive income is limited to the 
cumulative change in fair value of the hedged item, determined 
on a present value basis, from inception of the hedge. Any 
ineffective portion of changes in the fair value of the derivative is 
recognised immediately in profit or loss.

If the hedge no longer meets the criteria for hedge accounting 
or the hedging instrument is sold, expires, is terminated or is 
exercised, then hedge accounting is discontinued prospectively.  
When hedge accounting for cash flow hedges is discontinued, 
the amount that has been accumulated in the cash flow hedging 
reserve remains in equity until it is reclassified to profit or loss in 
the same period or periods as the hedged expected future cash 
flows affect profit or loss. 

If the hedged future cash flows are no longer expected to occur, 
then the amounts that have been accumulated in the cash flow 
hedging reserve and the cost of hedging reserve are immediately 
reclassified to profit or loss.

Translation risk
Exchange differences arising from the translation of the 
net investment in foreign operations are reported in other 
comprehensive income and accumulated in the translation 
reserve. Gains and losses on those hedging instruments 
designated as hedges of the net investment in foreign operations, 
are recognised to the extent that the hedging relationship is 
effective; these amounts are included in exchange differences 
on translation of foreign operations as stated in the statement 
of comprehensive income. Gains and losses relating to hedge 
ineffectiveness are recognised immediately in the Income 
Statement for the period. Gains and losses accumulated in the 
translation reserve are reclassified to the Income Statement when 
the foreign investment is disposed of. Non-derivative financial 
instruments comprise investments in equity and debt securities, 
trade and other receivables, cash and cash equivalents, loans 
and borrowings, and trade and other payables.

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

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Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

115

2. Summary of significant accounting policies 
continued
2.13 Non-derivative financial instruments
Modifications of financial instruments (including loans and 
borrowings) are reviewed quantitatively and qualitatively 
to determine if the modification is ‘substantial’. Substantial 
modification of a financial liability results in derecognition of 
the original balance, and recognition of a new financial liability 
at fair value. The difference between the carrying amount 
of the original financial liability and the fair value of the new 
financial liability is charged to the Income Statement. A non-
substantial modification of financial liability does not result in the 
derecognition of the original balance, however it may also result 
in a gain or loss recognised in the income statement.

Trade and other receivables
Trade and other receivables are recognised initially at fair value. 
Subsequent to initial recognition they are measured at amortised 
cost using the effective interest method, less any impairment 
losses. The Group’s trade receivables are subject to the IFRS 9 
expected credit loss model. The Group has applied the simplified 
approach to measuring expected credit losses which uses a 
lifetime expected loss allowance based on historic default rates. 
The expected credit loss rate varies depending on whether and 
the extent to which settlement of the trade receivables is overdue.

Accrued income represents amounts owed unconditionally to 
the Group which have not been invoiced at the year end. For 
these assets, only the passage of time is required before payment 
becomes due.

Trade and other payables
Trade and other payables are recognised initially at fair value. 
Subsequent to initial recognition they are measured at amortised 
cost using the effective interest method.

Cash and cash equivalents
Cash and cash equivalents comprise cash balances and call 
deposits. Bank overdrafts that are repayable on demand and 
form an integral part of the Group’s cash management are 
included as a component of cash and cash equivalents for 
the purpose only of the cash flow statement. Dividends and 
interest received are included in investing activities. Dividends 
and interest paid are included in financing activities.

Investments in debt and equity securities
The Company’s investment and loans to subsidiaries is stated at 
amortised cost less impairment.

Interest-bearing borrowings
Interest-bearing borrowings are recognised initially at fair 
value less attributable transaction costs. Subsequent to 
initial recognition, interest-bearing borrowings are stated at 
amortised cost using the effective interest method. 

2.14 Employee benefits – Share-based  
payment transactions
Employees (including Executive Directors) of the Group 
receive part of their remuneration in the form of share-
based payments, whereby, depending on the scheme, 
employees render services in exchange for rights over shares 
(‘equity-settled transactions’) or entitlement to a future cash 
payment (‘cash-settled transactions’), the amount of which is 
determined with reference to the Company’s share price. 

The cost of equity-settled transactions with employees is 
measured, where appropriate, with reference to the fair value 
at the date on which they are granted. Where options need 
to be valued an appropriate valuation model is applied. The 
expected life used in the model has been adjusted, based 
on management’s best estimate, for the effects of exercise 
restrictions and behavioural considerations. The cost of 
equity-settled transactions is fully recharged to subsidiaries.

The cost of cash-settled transactions is measured with reference 
to the fair value of the liability, which is taken to be the closing 
price of the Company’s shares. Until the liability is settled it is 
remeasured at the end of each reporting period and at the date 
of settlement, with any changes in the fair value being recognised 
in the Income Statement.

The cost of equity-settled transactions is recognised, along with 
a corresponding increase in equity, over the years in which 
the performance conditions are fulfilled, ending on the date 
on which the relevant employees become fully entitled to the 
award (‘vesting date’). The cost of cash-settled transactions is 
recognised, along with a provision for expected cash settlement, 
over the vesting period.

At each reporting date, the cumulative expense recognised for 
equity-settled transactions reflects the extent to which the vesting 
period has expired and the number of awards that, in the opinion 
of management, will ultimately vest. Management’s estimates are 
based on the best available information at that date. No expense 
is recognised for awards that do not ultimately vest, except for 
awards where vesting is conditional upon a market condition, 
which are treated as vesting irrespective of whether or not the 
market condition is satisfied, provided that all other performance 
conditions are satisfied.

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116

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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2. Summary of significant accounting policies 
continued
2.15 Equity
The provision of shares to satisfy certain of the Group’s share 
option schemes can be facilitated by purchases of own shares 
by the Group’s Employee Benefit Trust. The costs of operating the 
Trust is borne by the Group but is not material. To date, no shares 
have been purchased by the Trust for satisfaction of outstanding 
or future share option awards.

The Employee Benefit Trust is considered to be controlled by the 
Group. The activities of the Trust are conducted on behalf of the 
Group according to its specific business needs in order to obtain 
benefits from its operation and, on this basis, the assets held by 
the Trust are consolidated into the Group’s financial statements.

‘Share capital’ represents the nominal value of equity shares.

‘Share premium’ represents the excess over nominal value of 
the fair value of consideration received for equity shares, net of 
expenses of the share issue.

‘Share option reserve’ represents equity-settled share-based 
employee remuneration.

‘Retained earnings’ represents retained profit.

‘Other reserve’ represents the difference between the fair value 
and nominal value of shares issued on a reverse takeover.

‘Cash flow hedging reserve’ represents the fair value of 
derivative financial instruments at the balance sheet date that 
are designated as cash flow hedges, net of deferred tax, less 
amounts reclassified through other comprehensive income.

‘Translation reserve’ represents gains and losses arising on 
translation of the net assets of overseas operations into the 
Group’s presentation currency of Sterling.

2.16 Provisions
Provisions are recognised when there is a present legal or 
constructive obligation as a result of a past event, for which it is 
probable that a transfer of economic benefits will be required 
for settlement and where a reliable estimate can be made of the 
amount of the obligation. Where material, provisions have been 
discounted to their present value.

Restructuring provisions are recognised when the Group has 
developed a detailed formal plan for the restructuring and has 
raised a valid expectation in those affected that it will carry out 
the restructuring by starting to implement the plan or announcing 
its main features to those affected by it. The measurement of 
a restructuring provision includes only the direct expenditures 
arising from the restructuring, which are those amounts that are 
both necessarily entailed by the restructuring and not associated 
with the ongoing activities of the entity

2.17 Business combinations
Business combinations are accounted for using the acquisition 
accounting method. Identifiable assets and liabilities acquired 
are measured at fair value at acquisition date. Costs related 
to the acquisition, other than those associated with the issue 
of debt or equity securities, are expensed as incurred. Any 
contingent consideration payable is recognised at fair value at 
the acquisition date. If the contingent consideration is classified 
as equity, it is not remeasured and settlement is accounted for 
within equity. Otherwise, subsequent changes to the fair value of 
the contingent consideration are recognised in profit or loss. The 
Group also engages in acquisitions of product-specific assets 
(such as brands – set out in note 2.9). 

Alliance Pharma plc Annual Report and Accounts 2022

Where elements of the consideration paid are variable and 
based on future revenues, the cost of the intangible asset 
recognised is based on the agreed minimum payments and any 
additional payments are expensed as the related sales occur.

In assessing whether an acquired set of assets and activities is a 
business or an asset, management will first elect whether to apply 
an optional concentration test to simplify the assessment. Where 
the concentration test is applied, the acquisition will be treated 
as the acquisition of an asset if substantially all of the fair value of 
the gross assets acquired (excluding cash and cash equivalents, 
deferred tax assets, and related goodwill) is concentrated in 
a single asset or group of similar identifiable assets. Where 
the concentration test is not applied, or is not met, a further 
assessment of whether the acquired set of assets and activities is 
a business will be performed.

2.18 Going concern
The Group is in a net current asset position of £58.5m (2021: 
£40.4m). The Group’s debt funding is provided by a £165m 
Revolving Credit Facility (‘RCF’), together with a £50m accordion 
facility, with a syndicate of lenders. This facility is available  
until July 2024 and the directors have a reasonable expectation 
that a refinancing of the facility will be concluded in the  
coming months. The amount drawn as at 31 December 2022  
was £134.1m (2021: £117.0m) and £134.0m as at  
28 February 2023. 

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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Financial Statements

Additional Information

117

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
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2. Summary of significant accounting policies continued
2.18 Going concern continued
The Directors have prepared cash flow forecasts for a period of 
12 months from the date of approval of these financial statements 
(the going concern period). These indicate that the Group will 
have sufficient funds, given the RCF financing available, to meet 
its liabilities as they fall due for that period. 

Also, the Directors have considered the sensitivity of cash flow 
forecasts to severe downside scenarios, including the impact 
of a potential payment of a £7.9m CMA fine. In particular, the 
Directors considered a reasonably possible downside scenario 
which models severe disruption to CBEC sales resulting in a 
decline in EBITDA against budget of over 30%. Even in this 
severe scenario, the forecasts indicate that the Group will 
have sufficient funds to meet its liabilities as they fall due, and 
will continue to comply with its loan covenants, throughout the 
forecast period. Only interest rate rises above current market 
projections would result in a breach of the interest cover covenant 
under this scenario. In isolation, interest rates would need to rise 
by over 2% (200bp) above current market projections to cause 
a breach in the interest cover covenant, before the impact of any 
mitigating actions.

The RCF is drawn in short to medium-term tranches of debt which 
are repayable within 12 months of draw-down. These tranches 
of debt can be rolled over provided certain conditions are met, 
including covenant compliance. All covenants have been fully 
complied with to date. The Group considers that it is highly 
unlikely it would be unable to exercise its right to roll-over the 
debt based on the forecast covenant compliance in the severe 
downside modelled above. Even in a more extreme scenario 
there are mitigating actions (within the control of the Group) 
it could take to maintain compliance with these conditions, 
including future covenant requirements. The Directors therefore 

believe that the Group has the ability and the intent to roll-
over the drawn RCF amounts when due and consequently has 
presented the RCF as a non-current liability. 

Consequently, the Directors are confident that the Company 
will have sufficient funds to continue to meet its liabilities as 
they fall due for at least 12 months from the date of approval 
of the financial statements and have therefore determined it is 
appropriate to adopt the going concern basis in preparing the 
financial statements.

2.19 Alternative performance measures
The performance of the Group is assessed using Alternative 
Performance Measures (‘APMs’). The Group’s results are 
presented both before and after non-underlying items. Adjusted 
profitability measures are presented excluding non-underlying 
items as we believe this provides both management and 
investors with useful additional information about the Group’s 
performance and aids effective comparison of the Group’s 
trading performance from one period to the next and with similar 
businesses. 

In addition, the Group’s results are described using certain 
other measures that are not defined under IFRS and are 
therefore considered to be APMs. These measures are used by 
management to monitor ongoing business performance against 
both shorter-term budgets and forecasts but also against the 
Group’s longer-term strategic plans. APMs are presented in  
note 31.

The Group does not consider adjusted profitability measures or 
APMs to be a substitute for, or superior to, IFRS measures.

3. Revenue and segmental information 
The Group’s reportable segments are the strategic business 
units that represent different parts of the overall product 
portfolio, these being Consumer Healthcare brands and 
Prescription Medicines. The business units are managed 
separately as each portfolio requires different expertise to 
deliver the corresponding product offering as a result of the 
inherently different characteristics of these product types.

Operating segments reflect the way in which information is 
presented to and reviewed by the CODM for the purposes 
of making strategic decisions and assessing Group-wide 
performance. The Group’s Board of Directors (‘the Board’) is 
the Group’s CODM. The Group evaluates performance of the 
operational segments on the basis of revenue and gross profit. 
Other than intangible assets, disclosed in note 11, assets and 
liabilities are reported to the Board at Group level and are not 
separated segmentally.

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

118

3. Revenue and segmental information continued
Revenue

Operating segment results

Revenue information by brand

Consumer Healthcare brands:
Kelo-Cote™ franchise
Amberen™
Nizoral™*
MacuShield™
Aloclair™
Vamousse™
Other Consumer Healthcare brands
Total revenue – Consumer Healthcare brands:
Prescription Medicines:
Hydromol
Flamma Franchise
Forceval
Other prescription medicines
Total revenue – Prescription Medicines
Total revenue 

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

50,039 
14,909 
17,231 
9,080 
9,272 
4,602 
15,489 
120,622 

8,070 
6,548 
5,872 
26,304 
46,794 
167,416 

48,845
19,233
14,189
8,829
5,773
4,110
14,397
115,376

7,009
6,610
5,685
28,527
47,831
163,207

* 

 Nizoral™ statutory revenue includes revenue generated on an agency basis. Nizoral™ revenue presented on a see-through Income Statement 
basis is included as an alternative performance measure in note 31.

Classification by geography is based on customer location. 

Revenue 

Cost of sales 

Gross profit

Revenue 

Cost of sales 

Gross profit

Year ended 31 December 2022

Consumer Healthcare £000s

Prescription Medicines
£000s 

120,622 

(43,019)

77,603 

46,794 

(22,714)

24,080 

Consumer Healthcare £000s

Year ended 31 December 2021 

Prescription Medicines
£000s 

115,376

(31,545)

83,831

47,831

(22,212)

25,619

Total 
£000s 

167,416 

(65,733)

101,683 

Total 
£000s 

163,207

(53,757)

109,450

Major customers 
The revenues from the Group’s largest customers in the year ended 31 December 2022 (customers 
separately comprising more than 10% of the Group’s revenue) are as follows. In 2021, no 
customers separately comprised 10% or more of revenue. 

Major customer 1 (Consumer Healthcare sales in 
EMEA and APAC)

Major customer 2 (Consumer Healthcare sales  
in APAC)

Year ended
31 December 2022
£000s

Year ended
31 December 2021
£000s

21,461 

14,228 

 17,898  

11,064 

For more information visit  
alliancepharmaceuticals.com

Europe, Middle East and Africa (EMEA)

Asia Pacific and China (APAC) 

Americas (AMER)

Total revenue

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

78,920 

59,186 

29,310 

167,416 

 89,188 

 48,030 

 25,989 

163,207

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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119

4. Profit before taxation

Profit before taxation is stated after charging/(crediting):

Amounts receivable by the Company’s auditor and its  
associates in respect of:

– The audit of these financial statements

– The audit of the financial statements of subsidiaries

– Other assurance services (covenant compliance and 
other regulatory compliance services)

Amortisation of intangible assets

Impairment of intangible assets

CMA provision

Share options charge 

Depreciation of plant, property and equipment

Gain on foreign exchange transactions

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

480

220

17

9,202 

18,234

–

92

1,558

(56)

96

326

5

8,530

6,150

7,900

2,250

1,575

(205)

5. Non-underlying items
The Group presents a number of non-IFRS measures which exclude the impact of significant non-
underlying items. This is to allow investors to understand the underlying trading performance of 
the Group, and can exclude items such as: amortisation and impairment of acquired intangible 
assets; restructuring costs; significant gains or losses on disposal; remeasurement and accounting 
for the passage of time in respect of contingent considerations; and the revaluation of deferred tax 
balances following substantial tax legislation changes. This assessment requires judgement to be 
applied by the Directors as to which transactions are non-underlying and whether this classification 
enhances the understanding of the users of the financial statements.

Year ended 
31 December 2022
 £000s

Year ended 
31 December 2021
 £000s

Amortisation of acquired intangible assets

Impairment of goodwill and intangible assets

CMA provision

Restructuring costs

Other

(7,238)

(18,234)

–

–

369

Total non-underlying items before taxation

(25,103)

Taxation on non-underlying items

Impact of UK tax rate change from 19% to 25%

Non-underlying taxation

2,962

–

2,962

Total non-underlying items after taxation

(22,141)

(7,168)

(6,150)

(7,900)

(2,420)

(423)

(24,061)

2,167

(4,972)

(2,805)

(26,866)

Amortisation of intangible assets
The amortisation costs of acquired intangible assets are a significant item considered unrelated to 
trading performance, and as such have been presented as non-underlying. This classification is in 
line with the majority of peer companies of the Group. 

Impairment of goodwill and intangible assets
The impairment reviews for the Group’s intangible assets resulted in impairment losses as the 
carrying value of certain cash-generating units exceeded estimated recoverable amounts. Further 
details are provided in note 11. The impairment losses are significant items resulting from changes 
in assumptions for future recoverable amounts. As such they are considered unrelated to 2022 
trading performance, and have been presented as non-underlying.

CMA provision
The CMA provision of £7.9m recognised in the year ended 31 December 2021 relates to the 
CMA Infringement Decision which is detailed further in note 20. This is considered unrelated to 
trading performance, and as such has been presented as non-underlying.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

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120

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

5. Non-underlying items continued
Restructuring costs
Costs of Group restructuring in the year ended 31 December 2021 (£2.4m) related to the closure 
of the Milan and Los Angeles offices. These costs are a significant item considered unrelated to 
2021 trading performance, and as such have been presented as non-underlying. 

Other non-underlying items
The other non-underlying items relate to capitalised professional fees in relation to the ScarAway™ 
acquisition which completed in March 2022. These costs were incurred in 2021 as non-underlying 
costs and capitalised in 2022 post-completion. 

Impact of UK tax rate change from 19% to 25% 
In the Budget on 3 March 2021, a change to UK corporation tax rates was announced, increasing 
the main rate from 19% to 25% with effect from 1 April 2023. The impact on deferred tax of this 
further rate increase is included in these financial statements as a non-underlying item for the year 
ended 31 December 2021.

7. Directors and employees
Employee benefit expenses for the Group (including Executive Directors) during the year were  
as follows:

Wages and salaries

Social security costs

Other pension costs (note 28)

Share-based employee remuneration (note 24)

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

18,777 

2,040 

1,345 

92

22,254 

18,886

2,077

1,306

2,250

24,519

The average number of employees of the Group (including Directors) during the year was:

6. Finance costs

Interest payable and similar charges

On loans and overdrafts

Amortised finance issue costs 

Interest on lease liabilities

Finance income

Interest income

Net exchange gains

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

Management and administration

Year ended 
31 December 2022
Number

Year ended 
31 December 2021
Number

249

255

(4,668)

(648)

(117)

(5,433)

16 

56 

72 

(2,904)

(639)

(103)

(3,646)

23

205

228

Key management of the Group is the Board of Directors (including Non-executive Directors)  
and the Senior Leadership Team (SLT). Benefit expenses in respect of the key management were  
as follows:

Key management remuneration

Pension contributions

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

1,699

114

1,813

3,442

121

3,563

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Finance costs – net

(5,361)

(3,418)

During the year contributions were paid to defined contribution schemes for two Executive 
Directors (2021: two).

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121

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
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7. Directors and employees continued
Gain on share options exercised by Executive Directors during the year was £90,000 (2021: 
£363,000). The notional non-cash IFRS 2 share-based payment expense in respect  
of Directors was £461,000 (2021: £256,000).

The amounts set out above include remuneration in respect of the highest-paid Director  
as follows:

Emoluments for qualifying services

Pension contributions

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

368

32

400

587

29

616

The notional non-cash IFRS 2 share-based payment expense in respect of the Director was 
£160,000 (2021: £177,000).

Average number of members of the Board of Directors (including Non-executive Directors) for the 
year ended 31 December 2022 was six (2021: six).

8. Taxation
Analysis of the charge for the period is as follows:

Corporation tax 

In respect of current period
Adjustment in respect of prior periods

Deferred tax (see note 22)

Origination and reversal of temporary differences
Adjustment in respect of prior periods

Taxation

Year ended
 31 December 2022
£000s

Year ended
 31 December 2021
£000s

5,669
110
5,779

(837)
(670)
4,272

6,069
(65)
6,004

4,471
363
10,838

The difference between the total tax charge shown above and the amount calculated by applying 
the standard rate of UK corporation tax to the profit before tax is as follows:

Profit before taxation

Profit before taxation multiplied by standard rate of 
corporation tax in the United Kingdom of 19.00% 
(2021: 19.00%)

Effect of:

Non-deductible expenses

Non-taxable income

Adjustment in respect of prior periods

Differences between current and deferred tax rates 

Differing tax rates on overseas earnings

Unrecognised losses

Foreign exchange

Share options

Movement in other tax provisions

Total taxation

Year ended
 31 December 2022
£000s
5,208

Year ended
 31 December 2021
£000s
18,157

989

3,449

2,583

–

(560)

(104)

(266)

(6)

1,427

315

(106)

4,272

1,888

(4)

298

4,972

114

246

96

(352)

131

10,838

A change to UK corporation tax was announced in the Budget on 3 March 2021, increasing the 
main rate of UK corporation tax from 19% to 25% with effect from 1 April 2023. The taxation 
charge for the year ended 31 December 2021 includes the impact on deferred tax of this increase.

The Group has calculated ‘underlying effective tax rate’ as an alternative performance measure in 
note 31.

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122

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

9. Dividends
An interim dividend of 0.592p per share for the 2022 financial year was paid on  
19 January 2023.

Amounts recognised as distributions to  
owners in 2022

Interim dividend for the 2021 financial year

Final dividend for the 2021 financial year

Total dividend

Year ended
 31 December 2022

Pence/share

£000s

0.563 

1.128 

1.691 

3,030 

6,086 

9,116 

A reconciliation of the weighted average number of Ordinary shares used in the measures is  
given below: 

Basic EPS calculation

Employee share options

Diluted EPS calculation

Year ended 
31 December 2022

Year ended 
31 December 2021

539,480,306 

535,295,583

5,800,317 

7,039,113

545,280,623 

542,334,696

The underlying basic EPS is intended to demonstrate recurring elements of the results of the Group 
before non-underlying items. A reconciliation of the earnings used in the different measures is  
given below:

The interim dividend for 2021 was paid on 7 January 2022. The final dividend for 2021 was paid 
on 7 July 2022.

Amounts recognised as distributions to owners 
in 2021

Interim dividend for the 2020 financial year

Final dividend for the 2020 financial year

Total dividend

Year ended
 31 December 2021

Pence/share

£000s

Earnings for basic and diluted EPS

Non-underlying items (note 5)

Earnings for underlying basic and diluted EPS

0.536 

1.074 

1.610 

2,857 

5,747 

8,604 

The resulting EPS measures are:

The interim dividend for 2020 was paid on 7 January 2021. The final dividend for 2020 was paid 
on 8 July 2021.

10. Earnings per share (EPS)
Basic EPS is calculated by dividing the earnings attributable to Ordinary shareholders by the 
weighted average number of Ordinary shares in issue during the year. For diluted EPS, the 
weighted average number of Ordinary shares in issue is adjusted to assume conversion of all 
dilutive potential Ordinary shares. There are no differences in earnings used to calculate each 
measure as a result of the dilutive employee share options. 

Basic EPS

Diluted EPS

Underlying basic EPS

Underlying diluted EPS

Year ended 
31 December 2022
£000s

Year ended 
31 December 2021
£000s

936

22,141

23,077 

7,319

26,866

34,185

Year ended 
31 December 2022
Pence

Year ended 
31 December 2021
Pence

0.17

0.17

4.28 

4.23 

1.37

1.35

6.39 

6.30 

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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123

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

11. Goodwill and intangible assets

The Group

Cost

 Goodwill
£000s

Consumer Healthcare 
brands and distribution 
rights £000s

Prescription Medicines 
brands and distribution 
rights £000s

Computer 
software 
£000s

Total
£000s

The Group

Cost

At 1 January 2022

32,382 

260,080 

151,544  15,043  459,049 

Additions

–

Exchange adjustments 2,244

16,386 

15,296 

–

249  16,635 

1,147 

– 18,687 

At 31 December 
2022

Amortisation and 
impairment

34,626 

291,762 

152,691  15,292  494,371 

At 1 January 2022

1,144 

8,185 

34,614  1,362 45,305 

 Goodwill
£000s

Consumer Healthcare brands 
and distribution rights £000s

Prescription Medicines 
brands and distribution rights 
£000s

Computer 
software 
£000s

Total
£000s

At 1 January 2021

32,404

258,203

152,890

– 443,497

Transfer from 
property, plant  
and equipment

Additions

Acquisition

–

–

(183)

–

–

–

–

–

–

Exchange adjustments

161

1,877

(1,346)

11,037

11,037

4,006

4,006

–

–

(183)

692

At 31 December 
2021

32,382

260,080

151,544

15,043 459,049

Amortisation and impairment

At 1 January 2021

1,144

6,459

23,022

–

30,625

Non-underlying 
impairment for  
the year

Non-underlying 
amortisation for  
the year

Underlying 
amortisation for  
the year

At 31 December 
2022

Net book amount

At 31 December 
2022

11,952

1,164 

5,118

– 18,234

–

–

226 

7,012 

–

7,238

–

–

1,964 

1,964

13,096

9,575

46,744

3,326 72,741

21,530

282,187 

251,895 

105,947 11,966 421,630

116,930  13,681 413,744

Non-underlying 
impairment for  
the year

Non-underlying 
amortisation for  
the year

Underlying 
amortisation for  
the year

At 31 December 
2021

Net book amount

At 31 December 
2021

–

–

–

1,500

4,650

226

6,942

–

–

6,150

7,168

–

–

1,362

1,362

1,144

8,185

34,614

1,362

45,305

For more information visit  
alliancepharmaceuticals.com

At 1 January 2022

31,238

31,238

At 1 January 2021

31,260

251,895

251,744

116,930

13,681 413,744

129,868

– 412,872

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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124

11. Goodwill and intangible assets continued
Acquisitions
Included in additions in the year is £15.2m relating to the purchase of the ScarAway™ brand asset 
which completed in March 2022 and £1.2m relating to the purchase of an Aloclair™ brand asset 
which completed in October 2022.

For Prescription Medicines brand assets, finite useful lives of up to 20 years were adopted 
prospectively from 1 January 2020. The determination of this lifespan considered all relevant 
factors for each individual asset, including typical pharmaceutical asset life cycles and the potential 
development of alternative treatments over time and the remaining useful lives of these brands are 
considered to remain appropriate.

Useful economic lives
The Group segregates its portfolio of assets into two areas: Consumer Healthcare brands and 
Prescription Medicines. The Directors have considered the continuing appropriateness of the useful 
economic lives assigned to the assets.

For the majority of Consumer Healthcare brand assets, indefinite useful lives have been judged 
to remain appropriate. This is due to the expected long-term growth profile of the Consumer 
Healthcare business and the enduring nature of the brands, which are supported by continuing 
marketing spend. It is the opinion of the Directors that the indefinite life assets meet the criteria set 
out in IAS 38. This assessment is made on an asset-by-asset basis taking into account:

 ›

how long the brand has been established in the market and subsequent resilience to economic 
and social changes;
stability of the industry in which the brand is used;
potential obsolescence or erosion of sales;
barriers to entry;

 ›
 ›
 ›
 › whether sufficient marketing and promotional resourcing is available; and
 ›

dependency on other assets with defined useful economic lives.

Certain brands were acquired with patent protection, which lasts for a finite period of time. It is the 
opinion of the Directors that these patents do not provide any incremental value to the value of the 
brand and therefore no separate value has been placed on these patents. This assessment is based 
on a view of future profitability after patent expiry and past experience with similar brands.

The Prescription Medicines brand assets have a weighted average remaining life of 17 years at  
31 December 2022 (2021: 18 years).

The net book value of intangible assets and goodwill which are considered to have indefinite useful 
lives are allocated to CGUs in the following table. Goodwill relating to the acquisition of certain 
assets and businesses from Sinclair IS Pharma plc is allocated to the group of related Consumer 
Healthcare and Prescription Medicines product CGUs. Other goodwill amounts are allocated to 
the product CGU with which they were originally acquired. Intangible assets that are considered to 
have indefinite lives all relate to the Consumer Healthcare segment, except for Sinclair Prescription 
Medicines goodwill.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

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125

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

11. Goodwill and intangible assets continued 
Useful economic lives continued

Amberen™

Nizoral™

Kelo-Cote™ (US rights and ScarAway™) 

Vamousse™

MacuShield™

Ashton and Parsons

Aloclair™ (non-Sinclair)

Lefuzhi

Anbesol

Aiweidi

Opus range

Cambridge intangibles

Products acquired from Sinclair 

Kelo-Cote™ (non EU, excluding US)

Kelo-Cote™ (EU)

Aloclair™ (Sinclair)

Atopiclair

 Goodwill
£000s

4,983

 –   

–

 –   

1,748 

–

–

–   

 –   

 –   

1,849 

598 

–

–

–

–

For more information visit  
alliancepharmaceuticals.com

Goodwill – Sinclair Prescription Medicines

Goodwill – Sinclair Consumer Healthcare

 Assets with indefinite lives

1,722   

10,630 

21,530

Impairment
As explained in note 2.9, all intangible assets are stated at cost less accumulated amortisation and 
impairment. 

The carrying amounts of the Group’s non-financial assets are reviewed at each reporting date to 
determine whether there is any indication of impairment. For intangible assets with an indefinite life, 
assets with a finite life that show indicators of impairment, and goodwill, this includes estimation 
of the recoverable amount. These assets are tested at CGU level (or at group of CGUs level in 
the case of goodwill relating to the acquisition of certain assets and businesses) as the Directors 
believe these CGUs generate largely independent cash inflows.

The impairment test involves determining the recoverable amount of the relevant CGU, which 
corresponds to the higher of the fair value less costs to sell or its value in use.

The value in use calculation uses cash flow projections based on financial forecasts for up to the 
next five years extrapolated to perpetuity. Financial forecasts for the following year are based on 
the approved annual budget. Financial forecasts for years two to five are based on the approved 
long-range plan. Margins are based on past experience and cost estimates.

As a result of the impairment review for the year ended 31 December 2022, the following 
impairment charges were identified:

 › Goodwill relating to Amberen™ impaired by £12.0m (2021: £nil) due to a reduction in 

expected cash flows because of challenging market conditions and an increase in the discount 
rate applied to these cash flows which is the result of increasing market interest rates.

 › Consumer healthcare brand and distribution rights assets impaired by £1.2m (2021: £1.5m) 

 ›

due to viability of future sales in the current market. 
Prescription medicine brand and distribution rights assets impaired by £5.1m (2021: £4.7m) 
due to viability of future sales in the current market, supply issues, and increasing costs resulting 
from changes in the regulatory framework.

31 December 2022

Consumer healthcare 
brands and  
distribution rights 
£000s

Total
£000s

100,000 

104,983

60,307 

60,307 

15,202

11,596 

8,740 

1,562 

1,184

1,009 

987 

138 

 –   

 –   

15,202

11,596 

10,488 

1,562 

1,184

1,009 

987 

138 

1,849 

598 

45,567 

45,567 

17,800 

17,800 

14,000 

14,000 

2,300 

 –   

 –   

2,300 

 1,722   

10,630 

280,392

301,922

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022    
Company Overview

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126

11. Goodwill and intangible assets continued
Key source of estimation uncertainty – value in use assumptions
For the year end impairment review, key assumptions on which cash flow projections depend are 
as follows (including our assessment of the estimation uncertainty arising):

Sensitivity analysis
The Group has conducted sensitivity analysis on the impairment tests. The valuations generally 
indicate sufficient headroom and, except for Amberen™ which is detailed below, the Group does 
not consider that any reasonably possible change in key assumptions could result in an impairment. 

Discount rates

 › Methodology: Cash flows are discounted at an appropriate rate, based on the Group’s post-
tax Weighted Average Cost of Capital (‘WACC’) adjusted where appropriate for country-
specific risks, of between 7.0%–12.4%, or pre-tax 9.4%–14.5% (2021: 6.3%–8.6%, or pre-
tax 7.9%–10.8%). The Group’s WACC has increased as a result of the increase in risk-free rate 
due to changes in government bond yields, the increase in small stock premium to recognise 
the Group’s reduction in market capitalisation, offset to an extent by a small reduction in the 
equity beta based on sector market data. 
Estimation uncertainty: The assumptions included in the compilation of the CGU-specific 
discount rates are designed to approximate the discount rate that a potential market participant 
would adopt. Given the nature of the Group’s business model, the discount rate necessarily 
includes estimation uncertainty.

 ›

Forecast cash flows
 › Methodology: Approved budgets and forecasts for up to five years, based on management’s 
best estimate of cash flows by individual CGU. These forecasts are then uplifted for the CGU’s 
remaining useful economic life, or to perpetuity for assets with indefinite useful lives, using 
growth/decline rates between -5.5% to 2.0% (2021: -2.5% to 2.0%) based on the Group’s 
long-term projections. 
Estimation uncertainty: The growth rates assumed in the Group’s budgets and forecasts 
inherently include estimation uncertainty relating to the achievement of commercial initiatives 
and external factors such as competition. 

 ›

Management has identified that for the goodwill and brand and distribution rights related to 
Amberen™, a reasonable possible change in two key assumptions could cause the carrying 
amount to exceed the recoverable amount:

1) The recoverable amount is sensitive to changes in the discount rate applied, particularly in the 
context of market volatility and increasing interest rates.

2) The recoverable amount is sensitive to changes in the cash flow forecasts which are dependent 
on key revenue growth assumptions.

The following table shows the potential impact of reasonably possible changes to individual 
assumptions on the estimated recoverable amount of the Amberen™ CGU. As the carrying value 
is equal to the recoverable amount at 31 December 2022, this would result in an increase in 
impairment.

Amberen™

Decrease in CGU recoverable amount £000s

2.0% (200bp) increase in  
pre-tax discount rate

20% reduction in cash flow 
forecasts, before the impact 
of mitigating actions

(20,598)

(17,700)

Headroom

–

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

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127

12. Property, plant and equipment

The Group

Cost

Computer  
software and 
equipment
£000s

Fixtures,
 fittings & 
equipment
£000s

Plant & 
machinery
£000s

Right-of- 
use lease 
assets
£000s

Total
£000s 

The Group

Cost

At 1 January 2021

At 1 January 2022

2,037 

3,730 

73 

6,306  12,146 

Additions

Additions

Transfers

Effects of movements in  
exchange rates

Disposals

153 

108

(30)

(69)

205 

(108)

323 

(206)

–    1,997 

2,355 

Transfer to intangible assets

–

–

Disposals

–

1 

 (172)   

122

 –   

(2,901)

(3,176)

Computer  
software and 
equipment
£000s

Fixtures,
 fittings & 
equipment
£000s

Plant & 
machinery
£000s

Right-of-
 use lease 
assets
£000s

Total
£000s 

13,048

162

(11,037)

2,511

1,323

–

(136)

(104)

32

41

–

–

6,739

22,330

275

1,801

–

(11,037)

(708)

(948)

At 31 December 2022

2,199 

3,944 

74 

5,230  11,447

Depreciation

At 1 January 2022

Provided in the year

Transfers

Effect of movements in exchange rates

Disposals

1,670 

1,741 

153 

108

(5)   

(69)

541 

(108)

 32   

(6)

36 

13 

–

 –   

 –   

3,873 

7,320 

851 

1,558 

–

–

(60) 

(33)

(2,901)

(2,976)

At 31 December 2022

1,857 

2,200 

49 

1,763 

5,869 

Net book amount

At 31 December 2022

At 1 January 2022

342 

1,744 

367 

1,989 

25 

37 

3,467 

5,578 

2,433 

4,826 

At 31 December 2021

2,037

3,730

73

6,306

12,146

Depreciation

At 1 January 2021

Provided in the year

Effect of movements in exchange rates

Disposals

1,620

1,408

186

–

446

(9)

(136)

(104)

8

28

–

–

3,373

915

–

6,409

1,575

(9)

(415)

(655)

At 31 December 2021

1,670

1,741

36

3,873

7,320

Net book amount

At 31 December 2021

At 1 January 2021

367

11,428

1,989

1,103

37

24

2,433

4,826

3,366

15,921

Property, plant and equipment of £3.2m is located within the United Kingdom (2021: £4.1m). The 
remaining balance is located in France, China, Singapore, Spain, Germany and the United States 
of America. Right-of-use assets relate to the Group’s leased offices. 

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

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128

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

13. Investments

The Company

Cost

At 1 January 2022

Net movements 

At 31 December 2022

At 1 January 2021

Net movements

At 31 December 2021

The investment balance includes outstanding intercompany debt due from subsidiaries of £176.1m 
(note 29). The Directors do not consider that this amount will be demanded by the Company and 
therefore it has been classified as an investment. No provision has been recognised for estimated 
credit losses on loans to subsidiaries, as it is considered these would be immaterial.

The net movement for the year ended 31 December 2022 included interest charged of £8.4m 
(2021: £6.1m), the recharge of the share option charge of £1.3m (2021: £1.1m), the dividend 
received of £nil (2021: £2.6m) and payments received to reduce the loan.

The subsidiary and associated undertakings where the Group held 20% or more of the equity 
share capital at 31 December 2022 are shown below:

For more information visit  
alliancepharmaceuticals.com

Company

Investment and loans to 
subsidiary undertakings 
£000s

Advanced Bio-Technologies Inc.

Alliance Pharma France SAS

Alliance Pharma S.r.l.

Country of registration  
or incorporation

%

owned Nature of business

USA

France

Italy

100 Pharmaceutical sales

100 Pharmaceutical sales

100 Pharmaceutical sales

199,348 

(2,095)

197,253

199,776

(428)

199,348

Alliance Pharmaceuticals Limited*

England & Wales

100 Pharmaceutical sales

Alliance Lifescience Technology (Shanghai) 
Co., Limited

Alliance Pharmaceuticals Spain SL*

Alliance Pharma Inc.

China

Spain

USA

100 Pharmaceutical sales

100 Pharmaceutical sales

100 Pharmaceutical sales

Alliance Pharmaceuticals (Thailand) Co., Ltd

Thailand

100 Pharmaceutical sales

Alliance Pharmaceuticals (Philippines) 
Corporation

Philippines

100 Pharmaceutical sales

Alliance CHC (India) Private Limited 

India

100 Pharmaceutical sales

Alliance Pharma (Ireland) Limited

Republic of Ireland 100 Pharmaceutical sales

Alliance Pharmaceuticals GmbH*

Germany

100 Non-trading

Alliance Pharmaceuticals GmbH* – Swiss 
Branch

Switzerland

100 Non-trading

Alliance Pharmaceuticals SAS*

France

100 Non-trading

Alliance Pharma (Singapore) Private Limited* Singapore

100 Non-trading

Alliance Pharmaceuticals (Asia) Limited*

Hong Kong

100 Non-trading

Opus Healthcare Limited

Republic of Ireland 100 Dormant

Alliance Consumer Health Limited

England & Wales

100 Dormant

Alliance Generics Limited

Alliance Health Limited

England & Wales

100 Dormant

England & Wales

100 Dormant

Alliance Healthcare Limited

England & Wales

100 Dormant

Caraderm Limited

Dermapharm Limited

Northern Ireland

100 Dormant

England & Wales

100 Dormant 

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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129

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

13. Investments continued

Company

Country of registration  
or incorporation

%

owned Nature of business

MacuVision Europe Limited

England & Wales

100 Dormant

Maelor Laboratories Limited 

England & Wales

100 Dormant

Opus Group Holdings Limited

England & Wales

100 Dormant

Opus Healthcare Limited

England & Wales

100 Dormant

* 

Investments held directly by Alliance Pharma plc.

The registered address in each country is as follows:

Notes to the Financial Statements  109

Territory

Company

Registered Office Address

USA

Advanced Bio-Technologies Inc. 11000 Regency Pkwy, Ste 106, Cary NC 

Alliance Pharma Inc.

27518, United States

11000 Regency Pkwy, Ste 106, Cary NC 
27518, United States

France

Alliance Pharmaceuticals SAS

13 rue Paul Valéry, 75016, Paris, France

Alliance Pharma France SAS

13 rue Paul Valéry, 75016, Paris, France

China

Alliance Pharmaceuticals 
Lifescience Technology 
(Shanghai) Co.,Limited

Suite 701, NanFung Tower, No. 1568, Road 
Huashan, Shanghai, 200030, P.R.China 

Germany

Alliance Pharmaceuticals GmbH Niederkasseler Lohweg 175, 40547,  

Dusseldorf, Germany

Hong Kong Alliance Pharmaceuticals  
(Asia) Limited

Room 2105, 21/F Office Tower, Langham Place, 
8 Argyle Street, Mongkok, Kowloon, Hong Kong

Italy

Alliance Pharma S.r.l.

Viale Francesco Restelli 5, 20124, Milano, Italy

Republic of 
Ireland

Alliance Pharma (Ireland) Limited United Drug House, Magna Drive, Dublin, 

D24 X0CT, Ireland

For more information visit  
alliancepharmaceuticals.com

Territory

Company

Registered Office Address

Opus Healthcare Limited

6th Floor, South Bank House, Barrow Street, 
Dublin 4

Singapore

Alliance Pharma (Singapore) 
Private Limited

1 Scotts Road, Shaw Centre 22-06, 228208, 
Singapore

Spain

Alliance Pharmaceuticals  
Spain SL

Regus Business Center Torre de Cristal, Paseo de 
la Casstellana, 259 C Planta 18, Cuatro Torres 
Business area 28046, Madrid, Spain

Switzerland 
(Branch)

Alliance Pharmaceuticals  
GmbH Düsseldorf

Bahnhofstrasse 37, Postfach 2818, CH-8021 
Zürich, Switzerland

Thailand

Alliance Pharmaceuticals 
(Thailand) Co., Ltd

All Companies

England & 
Wales

Northern 
Ireland

No. 444 Olympia Thai Tower, 8th Floor, 
Ratchadapisek Road, Samsennok Sub-district, 
Huaykwang District, Bangkok, Thailand

Avonbridge House, Bath Road, Chippenham, 
Wiltshire, SN15 2BB

Caraderm Limited

6 Trevor Hill, Newry, County Down, BT34 1DN

Philippines  Alliance Pharmaceuticals 
(Philippines) Corporation 

India 

Alliance CHC (India)  
Private Limited 

30/F 88 Corporate Center Sedeno Cor.Valero 
STS., BEL-AIR 1209, City of Makati NCR, Fourth 
District, Philippines 

314, Bhaveshwar Arcade Annexe, LBS Marg, 
Opp. Shreyas Cimema, Ghatkopar West 
Mumbai, Bandra Suburban, MH 400086 IN 

Unless otherwise stated, the share capital comprises Ordinary shares and the ownership 
percentage is provided for each undertaking. All subsidiary undertakings prepare accounts  
to 31 December.

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130

14. Inventories

The Group

Finished goods

Work in progress

Raw materials

Inventory provision

31 December 2022
£000s

31 December 2021
£000s

21,804

416

5,083

(3,017)

24,286 

20,111

23

4,177 

(3,236)

21,075

Inventory costs expensed through the Income Statement during the year were £59,566,000 
(2021: £52,932,000). During the year £993,000 (2021: £534,000) was recognised as an 
expense relating to the write-down of inventories to net realisable value. 

15. Trade and other receivables

Trade receivables

Other receivables

Prepayments

Accrued income

The Group

The Company

31 December 2022
£000s

31 December 2021
£000s

31 December 2022
£000s

31 December 2021
£000s

44,764 

23,929

2,775 

1,094 

691 

1,953

3,102

1,837

49,324 

30,821

 –   

85 

8 

 –   

93 

–

31

8

–

39

Accrued income, which is all classified as not past due, represents amounts owed unconditionally 
to the Group which have not been invoiced at the year end. For these assets, only the passage of 
time is required before payment becomes due.

The ageing of trade receivables of the Group as at 31 December is detailed below:

Trade receivables, net of estimated  
allowances for expected credit losses

31 December 2022
£000s

31 December 2021
£000s

Not past due

1–30 days past due

31–60 days past due 

61–90 days past due 

Past 91 days

41,642 

2,514 

432 

176 

 –   

20,405

2,573

633

318

–

44,764 

23,929

Trade receivables, gross of estimated allowances for expected  
credit losses

31 December 2022
£000s

31 December 2021
£000s

Not past due

1–30 days past due

31–60 days past due 

61–90 days past due 

Past 91 days

41,642 

2,514 

432 

197 

390 

20,405

2,573

633

389

780

45,175 

24,780

As at 31 December 2022, trade and other receivables of £411,000 (2021: £851,000) were past 
due and impaired.

To manage credit risk customers are required to pay in accordance with agreed terms. Our 
settlement terms are generally due within 30 or 60 days from the end of the month of sale.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

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131

16. Cash and cash equivalents

The Group

The Company

31 December 2022
£000s

31 December 2021
£000s

31 December 2022
£000s

31 December 2021
£000s

10,556 

8,214 

3,758 

3,991 

5,195 

17,541

3,862

2,427

3,060

2,171

50 

141

–

–

–

–

–

–

–

–

31,714 

29,061

50 

141

Sterling

Euros

US Dollars

Thai Baht

Other currencies

Cash at bank and in 
hand

17. Trade and other payables 

The Group

The Company

31 December 2022
£000s

31 December 2021
£000s

31 December 2022
£000s

31 December 2021
£000s

Trade payables

18,567 

8,341

Other taxes and social 
security costs

Accruals 

Other payables

Lease liabilities

1,546 

13,972 

918 

613 

2,773

17,512

848

456

35,616 

29,930

111 

–

644 

–

–

755 

–

–

368

–

–

368

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
alliancepharmaceuticals.com

18. Loans and borrowings
The Group has a £165m fully Revolving Credit Facility (‘RCF’), together with a £50m Accordion 
Facility, with a syndicate of lenders. This facility is available until July 2024. This has been classified 
as a non-current liability (note 2.18). The bank facility is secured by a fixed and floating charge 
over the Company’s and Group’s assets registered with Companies House. The loan commitments 
are all ‘investment grade’ as at the balance sheet date.

The Group

 The Company

31 December 2022
£000s

31 December 2021
£000s

31 December 2022
£000s

31 December 2021
£000s

Non-current

Bank loans:

Secured 

134,065 

117,025

Finance issue costs

(321)

(965)

133,744 

116,060

Movement in loans and borrowings

At 1 January 

Net (payments)/receipts from borrowing

Additional prepaid arrangement fees

Amortisation of prepaid arrangement fees

Exchange movements*

At 31 December

–

–

–

–

–

–

31 December 2022
£000s

31 December 2021
£000s

116,060 

13,664 

–

648 

3,372 

138,328

(22,587)

–

628

(309)

133,744 

116,060

*  

 Exchange movements on loans and borrowings with effective net investment hedges are reported in other comprehensive income and 
accumulated in the translation reserve.

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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132

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
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19. Other non-current liabilities

The Group

 The Company

31 December 2022
£000s

31 December 2021
£000s

31 December 2022
£000s

31 December 2021
£000s

Lease liabilities

Other non-current 
liabilities

20. Provisions

3,219 

196

3,415 

2,426

211

2,637

–

–

–

At 1 January 2022

Provisions utilised during the year

Exchange differences

At 31 December 2022

CMA provision 
(£000s)

7,900 

 –   

 –   

7,900 

Restructuring 
provision 
(£000s)

1,569 

(1,078)

31 

522 

–

–

–

Total 
(£000s)

9,469 

(1,078)

31 

8,422 

On 23 May 2019 the UK’s Competition and Markets Authority (‘CMA’) issued a Statement 
of Objection alleging anti-competitive agreement involving the Group and certain other 
pharmaceutical companies in relation to the sale of prescription prochlorperazine. 
Prochlorperazine is one of the Group’s smaller products and had peak sales in 2015 of £1.9m and 
sales of £0.1m in 2022 (2021: £0.7m).

On 3 February 2022, the CMA announced its finding that four companies, including Alliance, 
had infringed competition law (the ‘Infringement Decision’). The Alliance Board fundamentally 
disagrees with the CMA’s finding. 

The Group believes that it has a strong case and has appealed the CMA’s decision, and the 
proposed fine of £7.9m, with its appeal now fixed to be heard at the Competition Appeal Tribunal 
from 5 June 2023.

Despite its Appeal, the Directors believe that, as a result of the Infringement Decision, a provision of 
£7.9m should be recorded at 31 December 2022 (2021: £7.9m). 

This reflects the maximum amount of the proposed fine communicated by the CMA, and therefore, 
notwithstanding the Directors’ belief as to the merits of the grounds on which it is appealing the 
CMA decision, the Directors consider this to be the appropriate position given that, in the event that 
the Group’s appeal proved to be unsuccessful, the ultimate level of the fine cannot be greater than 
this. In addition, in the event the Group’s appeal were to prove to be unsuccessful, the Directors 
consider that there are strong grounds upon which the amount of the fine could be reduced. 
However, as this is a matter which cannot be predicted with certainty at this time the Directors 
believe that the most appropriate course of action is to include the maximum potential amount of 
the fine.

If the appeal is unsuccessful, the Group may also be liable for a proportion of the legal costs of the 
CMA relating to the appeal. The Group has not recorded a provision in relation to these potential 
litigation costs as their amount cannot be reliably estimated.

In accordance with IAS 37.92, the Group does not provide further information on the grounds that 
this could seriously prejudice the outcome of the appeal.

The restructuring provision of £0.5m at 31 December 2022 (2021: £1.6m) relates to the balance 
of restructuring costs in relation to the closure of the Milan office following a change to the 
operating model for our direct-to-market business in Italy. The remaining related outflows are 
expected to occur in the year ending 31 December 2023.

Alliance Pharma plcAnnual Report and Accounts 2022NOTES TO THE FINANCIAL STATEMENTS CONTINUEDAlliance Pharma plc Annual Report and Accounts 2022Company Overview

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133

21. Financial instruments
The Group uses financial instruments comprising borrowings, derivatives, cash and liquid 
resources, and various items such as trade receivables and trade payables that arise directly 
from its operations. The main risks arising from the Group’s financial instruments are liquidity risk, 
interest rate risk, foreign currency risk and credit risk. The Board is responsible for risk management 
policies on managing each of these, which are summarised below, except credit risk which is 
detailed in note 15.

Liquidity risk
The Group’s operations are financed by retained earnings and bank borrowings, with additional 
equity being raised on a periodic basis to finance larger acquisitions. Borrowings are denominated 
in Sterling, Euro and US Dollars. The purpose of Euro and US Dollar borrowings are to manage the 
currency exposure arising from the Group’s operations.

The Group has a £165m fully Revolving Credit Facility (‘RCF’), together with a £50m Accordion 
Facility, with a syndicate of lenders. This facility is available until July 2024. 

The RCF is drawn in short to medium-term tranches of debt which are repayable within  
12 months of draw-down. These tranches of debt can be rolled over provided certain  
conditions are met, including covenant compliance. The Group considers that it is highly unlikely 
it would be unable to exercise its right to roll-over the debt. This is due to mitigating actions it 
could take to maintain compliance with these conditions, including future covenant requirements, 
even in downside scenarios. The Directors therefore believe that the Group has the ability and 
the intent to roll-over the drawn RCF amounts when due and consequently has presented the 
RCF as a non-current liability. 

The Group also has access to an overdraft facility of £2.0m.

The maturity profile of the Group’s financial gross (capital and interest) liabilities, except forward 
foreign exchange contracts for which maturity is disclosed separately, at the year-end is as follows:

31 December 2022

In one year 
or less
£000s

In more than 
one year, but not 
more than two
£000s

In more than two 
years, but not 
more than five
£000s

In more than five 
years
£000s

Total
£000s

35,003 

134,065 

613 

169,681 

–

–

594

594

–

–

1,263

1,263

–

–

35,003 

134,065 

1,362

3,832 

1,362

172,900 

Trade and other 
payables

Bank loans*

Lease liabilities

* 

 Includes an amount of £130.1m (2021: £117.1m) in respect of gross contractual cash flows payable under the RCF; these are shown as due 
within one year or less to reflect the contractual maturity of the tranches drawn down at 31 December 2022. The RCF is classified as a non-
current liability as the Directors have assessed that the Group has the ability and the intent to roll over the drawn RCF amounts when due.

31 December 2021

In one year 
or less
£000s

In more than one 
year, but not more 
than two
£000s

In more than two 
years, but not more 
than five
£000s

In more than five 
years
£000s

36,166

117,057

539

153,762

–

–

391

391

–

–

900

900

–

–

1,244

1,244

Total
£000s

36,166

117,057

3,074

156,297

Trade and other 
payables

Bank loans*

Lease liabilities

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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134

21. Financial instruments continued
Liquidity risk continued
The maturity profile of the Company’s financial gross liabilities (capital and interest) at the year end 
is as follows:

Because of the size of the Euro-denominated loan, a 0.5% increase or decrease in EURIBOR 
would not have affected pre-tax profits in 2022.

A 0.5% increase in US LIBOR would have reduced pre-tax profits by approximately £0.1m in 
2022. A 0.5% decrease would have the opposite effect.

Trade and other payables 

Interest rate risk
The Group’s debt is provided on a floating interest rate basis.

31 December 2022 
In one year or less 
£000s

31 December 2021 
In one year or less 
£000s

755

368

The interest rate exposure of the financial liabilities of the Group at the period end was:

Floating rate interest exposure

At 31 December 2022

Bank loans – Sterling denominated

Bank loans – Euro denominated

Bank loans – US Dollar denominated

Total financial liabilities

Unamortised issue costs

Net book value of  
financial liabilities

31 December 2022 
£000s

31 December 2021
£000s

96,817 

6,987 

30,261 

134,065 

(321)

96,817

7,895

12,313

117,025

(965)

133,744 

116,060

The Sterling floating rate borrowings bear interest at a rate based on SONIA for the year ended 
31 December 2022. The Euro floating rate borrowings bear interest at a rate based on EURIBOR. 
The US Dollar floating rate borrowings bear interest at a benchmark rate (US Dollar LIBOR).

A 0.5% increase in SONIA would have reduced pre-tax profits by approximately £0.5m in 2022. 
A 0.5% decrease would have the opposite effect.

Currency risk
The Group is exposed to transactional foreign currency risk to the extent that there is a mismatch 
between the currencies in which sales, purchases, receivables and borrowings are denominated 
and the respective functional currencies of Group companies. The functional currencies of Group 
companies are primarily Sterling, Euro, US Dollars and Hong Kong Dollars. 

Approximately 25% of the Group’s sales are invoiced in Euro, 33% invoiced in US Dollars and 6% 
invoiced in Hong Kong Dollars. The majority of other Group sales are invoiced in Sterling.

The Group’s risk management policy is to hedge up to 75% of its estimated net foreign currency 
exposure in respect of forecast sales and purchases for up to the next 18 months at any point 
in time. The Group uses forward foreign exchange contracts to hedge its currency risk. These 
contracts are generally designated as cash flow hedges.

After the impacts of hedging, 5% weakening or strengthening of Sterling against the Euro 
would have resulted in £0.3m gain or loss to EBITDA (note 31) in 2022. On the same basis, 5% 
weakening or strengthening of Sterling against the US Dollar would have resulted in a £0.7m gain 
or loss to EBITDA in 2022.

Net investment hedges
The Group uses currency-denominated borrowings to hedge the exposure of a portion of its net 
investment in overseas operations against changes in value due to changes in foreign exchange 
rates. The net investment hedge was tested for effectiveness during the year and found to be 
effective. As the Group repays its foreign-denominated borrowings the hedged portion of the net 
investment is reduced.

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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135

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

21. Financial instruments continued
Fair value measurement
The Group has adopted IFRS 13 for financial instruments that are measured in the Group balance 
sheet at fair value. This requires disclosure of fair value measurements by level of the following fair 
value measurement hierarchy:

 ›
 ›

 ›

quoted prices (unadjusted) in active markets for identical assets or liabilities (Level 1);
inputs other than quoted prices included within Level 1 that are observable for the asset  
or liability, either directly (that is, as prices) or indirectly (that is, derived from prices)  
(Level 2); and
inputs for the asset or liability that are not based on observable market data (that is, 
unobservable inputs) (Level 3). 

The Group’s financial instruments held at fair value (or for which fair value is disclosed) in the scope 
of IFRS 13 are as follows:

Forward foreign exchange contracts (Level 2)
The Group’s currency rate swaps are not traded in active markets. These have been fair valued 
using observable currency rates. The effects of non-observable inputs are not significant for 
currency rate swaps. 

Counterparty banks perform valuations of currency rate swaps for financial reporting purposes, 
determined by discounting the future cash flows at rates determined by year-end spot and 
forward rate. The valuation processes and fair value changes are discussed by the Audit and Risk 
Committee and the Finance team at least every half year, in line with the Group’s reporting dates.

Forward foreign exchange contract assets and liabilities are presented in ‘Derivative financial 
instruments’ (either as assets or as liabilities) within the statement of financial position. 

At 31 December 2022, the Group held the following forward exchange contracts to hedge 
exposures to changes in foreign currency rates:

Forward foreign exchange 
contracts

Level

2

31 December 2022
Carrying value
£000s

31 December 2021
Carrying value
£000s

174

174

64

64

For the other financial assets and liabilities, the carrying amount is a reasonable approximation 
of fair value and therefore no further disclosure is provided. The valuation techniques used for 
instruments categorised in Level 2 are described below:

Forward exchange contracts

Net exposure (£000s)

Average GBP:USD forward contract rate

Average GBP:EUR forward contract rate

Average GBP:HKD forward contract rate

Maturity

1–6 months

6–12 months

More than  
one year

117

1.195

1.131

–

40

1.200

1.123

–

17

1.196

1.120

–

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136

21. Financial instruments continued
At 31 December 2021, the Group held the following forward exchange contracts to hedge 
exposures to changes in foreign currency rates:

Maturity

1–6 months

6–12 months

More than  
one year

Forward exchange contracts

Net exposure (£000s)

Average GBP:USD forward contract rate

Average GBP:EUR forward contract rate

54

1.370

1.138

10

1.367

–

Average GBP:HKD forward contract rate

10.508

10.488

–

–

–

–

Group
Classification of the Group’s financial assets and liabilities is set out below:

Financial assets

Financial assets at amortised cost

Trade receivables

Accrued income

Cash and cash equivalents

Derivative financial instruments

Used for hedging 

31 December 2022
£000s

31 December 2021
£000s

44,764

691

31,714

174

77,343

23,929

1,837

29,061

64

54,891

Financial liabilities

Financial liabilities at amortised cost

Trade and other payables

Loans and borrowings

Lease liabilities

31 December 2022
£000s

31 December 2021
£000s

33,457

134,108

3,832

171,397

36,166

117,057

2,882

156,105

Company
Classification of the Company’s financial instruments is set out below:

Financial assets

Financial assets at amortised cost

Trade and other receivables 

Financial liabilities

Financial liabilities at amortised cost

31 December 2022
£000s

31 December 2021
£000s

–

31

31 December 2022
£000s

31 December 2021
£000s

Trade and other payables 

755

368

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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21. Financial instruments continued
Reconciliation to cash flow movements

Cash flows

Non-cash changes

2021
£000s

Principal
£000s

Interest
£000s

Gross loans and borrowings

117,025

13,664

Prepaid arrangement fees 

Accrued interest

Lease liabilities

(965)

32

2,882

–

–

(961)

–

–

(4,657)

(147)

Foreign 
exchange*
£000s

3,376

–

–

Net additions
£000s 

Amortisation
£000s

Interest
£000s

2022
£000s

–

–

–

–

644

–

–

–

–

4,668

134,065

(321)

43

117

3,832

(56)

1,997

* 

 Exchange movements on loans and borrowings with effective net investment hedges are reported in other comprehensive income and accumulated in the translation reserve.

Derivative financial instruments

Current portion

Non-current portion

Forward exchange swap – cash flow hedge

 31 December 2022
Assets/(Liabilities)
£000s

 31 December 2021
Assets/(Liabilities)
£000s

157

17

174

 64

–

64

The cash flow hedges were tested for 
effectiveness both retrospectively and 
prospectively as at 31 December 2022. 
They were found to be highly effective, with 
the ineffective element being immaterial. 
The amount recognised through the Income 
Statement in finance costs for interest rate 
swaps during the year was a charge of 
£nil (2021: £nil). The amounts recognised 
through the Income Statement in respect 
of the forward foreign exchange contracts 
during the year was a credit of £1,060,000 
in revenue (2021: credit of £982,000). 

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

22. Deferred tax

The Group

Accelerated capital allowances on tangible assets

Temporary differences: trading

Temporary differences: non-trading

 31 December 2022
£000s

 31 December 2021
£000s

1,057 

205 

1,630 

(464)

291

915

Accelerated allowances on intangible assets

(14,085)

(13,452)

Initial recognition of intangible assets from  
business combination

Share-based payments

Foreign exchange forward contracts 

Losses and unrelieved interest

Recognised as:

Deferred tax asset

Deferred tax liability

(51,440)

167 

(44)

1,058 

(61,452)

4,117

(65,569)

(47,796)

1,819

(16)

501

(58,202)

3,526

(61,728)

Reconciliation of deferred tax movements:

The Group

Non-current assets

Intangible assets

1 January 
2022
£000s

Transfers 
£000s

Recognised 
in other 
comprehensive 
income/directly 
in equity

Recognised
in the income 
statement
£000s

31 December 
2022
£000s

(61,248)

(1,435)

(4,275)

1,433

(65,525)

Property, plant and equipment

(464)

1,435

–

86

1,057

Non-current liabilities

Derivative financial 
instruments

Other non-current liabilities

Equity

(16)

915

Share option reserve

1,819

Temporary differences

Trading

Losses

Recognised as:

Deferred tax asset

Deferred tax liability

291

501

(58,202)

3,526

(61,728)

(58,202)

–

–

–

–

–

–

–

–

–

(28)

715

–

–

(44)

1,630

(1,169)

(483)

167

–

–

(86)

557

205

1,058

(4,757)

1,507

(61,452)

–

–

–

–

–

–

4,117

(65,569)

(61,452)

The Group has unrecognised deferred tax assets of £354,000 in relation to losses  
(2021: £246,000).

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139

22. Deferred tax continued

23. Share capital

Transfers 
£000s

(670)

670

–

–

–

–

–

–

Recognised 
in other 
comprehensive 
income/directly 
in equity

Recognised
in the income 
statement
£000s

31 December 
2021
£000s

(284)

(5,086)

(61,248)

–

(217)

(464)

40

292

–

–

(16)

915

At 1 January 2021 – Ordinary shares of 1p each

Issued during the year

At 31 December 2021 – Ordinary shares of  
1p each

Issued during the year

 Allotted, called up and fully paid

No. of shares

532,919,111 

5,306,413 

538,225,524 

1,769,562 

£000s 

5,329 

53 

5,382 

18 

At 31 December 2022 – Ordinary shares of  
1p each

539,995,086 

5,400 

Between 1 January 2022 and 31 December 2022 1,769,562 shares were issued on the exercise 
of employee share options (2021: 5,306,413). 

626

169

1,819

The holders of Ordinary shares are entitled to receive dividends as declared from time to time and 
are entitled to one vote per share at meetings of the Company.

–

–

(201)

501

291

501

674

(4,834)

(58,202)

3,526

(61,728)

(58,202)

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

The Group

Non-current assets

1 January 
2021
£000s

Intangible assets

(55,208)

Property, plant and equipment

(917)

Non-current liabilities

Derivative financial 
instruments

(56)

623

Notes to the Financial Statements  109

Other non-current liabilities

Equity

Share option reserve

1,024

Temporary differences

Trading

Losses

Recognised as:

Deferred tax asset

Deferred tax liability

492

–

(54,042)

2,139

(56,181)

(54,042)

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

For more information visit  
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23. Share capital continued
Potential share options commitment
Under the Group’s share option scheme for employees and Executive Directors, options have been 
granted to subscribe for shares in the Company at prices ranging from 0.00p to 102.80p (2021: 
0.00p to 102.80p). Options are exercisable three years after date of grant, but in certain instances 
this can be extended to five years. Options outstanding are as follows:

Year of grant

Exercise price
Pence

Exercise from

2012

2013

2014

2015

2015

2016

2016

2017

2018

2019

2019

2020

2020

2021

2021

2022

2022

29.25

37.25

33.75

43.75

46.75

47.50

47.50

53.00

81.60

76.90

0.00

73.70

0.00

102.80

0.00

58.20

0.00

2015

2016

2017

2018

2018

2019

2021

2020

2021

2022

2022

2023

2023

2024

2024

2025

2025

Scheme

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

LTIP

CSOP

LTIP

CSOP

LTIP

CSOP

LTIP

31 December 2022
Number (000s)

31 December 2021
Number (000s)

–

233 

281 

350 

500 

619 

1,400 

2,366 

3,241 

4,412 

226 

4,231 

542 

6,044 

468 

7,837 

877 

41

263

321

719

500

1,077

1,800

2,877

4,171

5,422

529

5,042

628

7,012

531

–

–

33,627

30,933

The weighted average remaining contractual life at 31 December 2022 is 7.8 years (2021: 
7.8 years).

The provision of shares to satisfy certain of the Group’s share option schemes can be facilitated by 
purchases of own shares by the Group’s Employee Benefit Trust. The cost of operating the Trust is 
borne by the Group but is not material. To date, no shares have been purchased by the Trust for 
satisfaction of outstanding or future share option awards.

Managing capital
Our objective in managing the business’s capital structure is to ensure that the Group has the 
financial capacity, liquidity and flexibility to support the existing business and to fund acquisition 
opportunities as they arise.

The capital structure of the Group consists of net bank debt and shareholders’ equity. 
At 31 December 2022 net debt was £ 102.0m (2021: £87.0m) (note 31), whilst shareholders’ 
equity was £287.7m (2021: 282.5m).

The business is profitable and cash-generative. The main financial covenants applying to bank 
debt are that leverage (the ratio of net bank debt to EBITDA) should not exceed 3.0 times, and 
interest cover (the ratio of EBITDA to finance charges) should not be less than 4.0 times. The Group 
complied with both of these covenants in 2022 and 2021.

Smaller acquisitions are typically financed using bank debt, while larger acquisitions typically 
involve a combination of bank debt and additional equity. The mixture of debt and equity is varied, 
taking into account the desire to maximise the shareholder returns while keeping leverage at 
comfortable levels.

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141

24. Share-based payments
Under the Group’s share option scheme for employees and Executive Directors, options to 
subscribe for shares in the Company are granted normally once each year. The contractual life of 
an option is ten years from date of grant. Generally, options granted become exercisable on the 
third anniversary of the date of grant, but in certain instances this can be extended to five years. 
Exercise of an option is normally subject to continued employment. Options are valued by a third-
party provider using the Black-Scholes option-pricing model. 

Share options and weighted average exercise price are as follows for the reporting 
periods presented:

2022

2021

Number 
 (000s)

30,933 

8,759 

(1,770)

(1,203)

(3,092)

Weighted  
average price
Pence

71.62 

52.34 

50.96 

63.21 

75.53 

Number 
 (000s)

36,583

7,674

(5,306)

(4,493)

(3,525)

33,627 

67.54 

30,933

13,628 

64.71 

11,845

Weighted  
average price
Pence

47.02

93.94

50.07 

56.12 

74.65 

71.62

60.12

Outstanding at start of 
year

Granted

Exercised (issued)

Exercised (withheld)

Forfeited

Outstanding at end  
of year

Exercisable at end  
of year

Share options were exercised throughout the financial year. Share options were exercised at prices 
of between 55.40p and 120.20p per share. 

Certain options are subject to EPS or Total Shareholder Return (TSR) accretion performance 
criteria; those outstanding are as follows:

Year of grant

Exercise price
Pence

Exercise from

31 December 2022 
Number (000s)

31 December 2021 
Number (000s)

2013

2014

2015

2016

2016

2017

2018

2019

2019

2020

2020

2021

2021
2022
2022

35.75

33.75

43.75 

47.50

47.50

53.00

81.60

76.90

0.00

73.70

0.00

102.80

0.00
58.20
0.00

2018

2017

2018

2019

2021

2020

2021

2022

2022

2023

2023

2024

2024
2025
2025

–

92 

104 

155 

1,400 

323 

1,639 

421 

226 

637 

542 

961 

468 
919
877

8,764

–

92

104

155

1,800

323

1,639

911

529

837

628

1,172

531
–
–

8,721

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

24. Share-based payments continued
The total expense for the year relating to share-based payment plans was £0.1m (2021: £2.3m), 
of which £1.1m (2021: £1.1m) related to equity-settled transactions and a credit of £1.0m (2021: 
debit of £1.2m) related to cash-settled transactions.

It is assumed that, on average, options will be exercised after five years. The expected volatility 
is based on historical volatility (calculated based on the weighted average remaining life of the 
share options), adjusted for any expected changes to future volatility due to publicly available 
information. The risk-free rate of return is based on UK Government bonds of a term consistent with 
the assumed option life.

The cash-settled transaction expense includes provision for social security charges based on the 
applicable social tax rate applied to the number of share awards which are expected to vest, 
valued with reference to the year-end share price.

The estimated total equity-settled fair value of the share options granted on 29 September 2022 
was £1,105,000. The model inputs were a market price of 58.2p, expected volatility of 31.93% 
and a risk-free rate of 3.96%. 

25. Cash generated from operations 

Group

Company

 Year ended
31 December 2022
£000s

 Year ended
31 December 2021
£000s

Year ended
31 December 2022
£000s

Year ended
31 December 2021
£000s

936

4,272 

7,319

10,838

5,429 

1,280

6,756

945

5,433 

3,646

–

–

(16)

(56)

–    

(23)

(205)

–

1,558 

1,575

27,436

(2,209)

14,680

1,842

(18,720)

(6,146)

7,281 

(1,078)

92 

–  

(326)

9,469

2,250

–

(8,427)

(6,121)

–  

–   

–  

–   

– 

(54)

387 

–   

– 

–

–

–

–

–

–

(3)

62

–

–

(2,600)

24,929 

44,919

(1,385) 

(961)

Profit for the year

Taxation

Interest payable and  
similar charges

Interest income

Foreign exchange (gain)/loss

Loss on disposal of intangibles

Depreciation of property, 
plant and equipment 

Amortisation and impairment  
of intangibles

Change in inventories

Change in trade and  
other receivables

Change in trade and  
other payables

Change in provisions

Share-based employee 
remuneration

Dividends received

Cash generated from/ 
(used in) operations

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Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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26. Capital commitments
The Group had capital commitments at 31 December 2022 totalling £22,000 (2021: £nil). 

29. Related party transactions 
During the year, the Company entered into the following transactions with related parties:

27. Contingent liabilities
Contingent liabilities are possible obligations that are not probable. The Group operates in a 
highly regulated sector and in markets and geographies around the world each with differing 
requirements. As a result, and in the normal course of business, the Group can be subject  
to a number of regulatory inspections, investigations and customer and other claims on an  
ongoing basis.

It is therefore possible that the Group may incur penalties for non-compliance. In addition,  
a number of the Group’s brands and products are subject to pricing and other forms of legal 
or regulatory restrictions from both governmental and regulatory bodies and also from third 
parties. Assessments as to whether or not to recognise a provision in respect of these matters are 
judgemental, as the matters are often complex and rely on estimates and assumptions as to  
future events.

As at 31 December 2022 there are no contingent liabilities (2021: £nil).

28. Pensions
The Group operates a defined contribution pension scheme for the benefit of Executive Directors 
and certain employees. 

The Company 
Transaction values for the year ended 

Amount due from 
related parties 

31 December 2022
£000s

31 December 2021
£000s

31 December 2022
£000s

31 December 2021
£000s

Alliance Pharmaceuticals 
Limited – Net funds 
received

Alliance Pharmaceuticals 
Limited – Interest received 

Alliance Pharmaceuticals 
Limited – Share-based 
payment recharge 

Alliance Pharmaceuticals 
Limited – Dividend 
declared and received 

(11,814)

(10,170) 

174,005

176,111

8,427

6,121 

1,281

1,021

–

2,600 

–

–

–

–

–

–

Net funds received represent net payments made against the intercompany loan by Alliance 
Pharmaceuticals Limited.

The Group

31 December 2022
£000s

31 December 2021
£000s

Contributions payable by the Group for the year

1,345

1,306

30. Ultimate controlling party
The Company’s shares are listed on the Alternative Investment Market (‘AIM’) and are held widely. 
There is no single ultimate controlling party.

31. Alternative performance measures
The performance of the Group is assessed using Alternative Performance Measures (‘APMs’). The 
Group’s results are presented both before and after non-underlying items. Adjusted profitability 
measures are presented excluding non-underlying items as we believe this provides both 
management and investors with useful additional information about the Group’s performance 
and aids a more effective comparison of the Group’s trading performance from one period to the 
next and with similar businesses. In addition, the Group’s results are described using certain other 
measures that are not defined under IFRS and are therefore considered to be APMs. 

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144

31. Alternative performance measures continued
These measures are used by management to monitor ongoing business performance against both 
shorter-term budgets and forecasts but also against the Group’s longer-term strategic plans. APMs 
used to explain and monitor Group performance are as follows:

Measure

Definition

Underlying 
EBIT and 
EBITDA

Earnings before interest, tax and non-underlying items (EBIT, also 
referred to as underlying operating profit), then depreciation, 
amortisation and impairment (EBITDA).

Reconciliation 
to GAAP measure

Note A below

Calculated by taking profit before tax and financing costs, excluding  
non-underlying items and adding back depreciation and 
amortisation.

EBITDA margin is calculated using see-though revenue.

Free cash 
flow

Free cash flow is defined as cash generated from operations less 
cash payments made for interest payable and similar charges, capital 
expenditure and tax.

Note B below

Net debt Net debt is defined as the Group’s gross bank debt position net of 

Note C below

finance issue costs and cash.

Underlying  
effective 
tax rate 

Underlying effective tax rate is calculated by dividing total taxation for 
the year less impact of tax rate changes and non-underlying charges, 
by the underlying profit before tax for the year.

Note D below

See-
through
Income 
Statement

Under the terms of the transitional services agreement with certain 
supply partners, Alliance receives the benefit of the net profit on 
sales of Nizoral™ from the date of acquisition up until the product 
licences in the Asia-Pacific territories transfer to Alliance. The net 
product margin is recognised as part of statutory revenue.

Note E below

The see-through Income Statement recognises the underlying sales 
and cost of sales which give rise to the net product margin, as 
management consider this to be a more meaningful representation of 
the underlying performance of the business, and to reflect the way in 
which it is managed.

Measure

Definition

Constant 
exchange 
rate (CER) 
revenue

Like-for-like revenue, impact of acquisitions, and total see-through 
revenue are stated so that the portion denominated in non-Sterling 
currencies is retranslated using foreign exchange rates from the 
previous financial year.

Like-for-
like

Like-for-like figures compare financial results in one period with 
those for the previous period, excluding the impact of acquisitions 
and disposals made in either period. For 2022, like-for-like revenue 
excludes the impact of ScarAway™ and Kelo-Cote™ US which were 
acquired in March 2022.

Reconciliation 
to GAAP measure

Note F below

Not needed

Operating 
costs

Defined as underlying administration and marketing expenses, 
excluding depreciation and underlying amortisation charges.

Not needed

A. Underlying EBIT and EBITDA

Reconciliation of Underlying EBIT and EBITDA

Profit before tax 

Non-underlying items (note 5)

Underlying profit before tax

Finance costs (note 6)

Underlying EBIT

Depreciation (note 12)

Underlying amortisation (note 11)

Underlying EBITDA

Underlying EBITDA margin

Year ended  
31 December 2022
£000s

Year ended  
31 December 2021
£000s

5,208

25,103

30,311 

5,361 

35,672 

1,558 

1,964 

39,194 

22.8%

18,157

24,061

42,218

3,418

45,636

1,575

1,362

48,573

28.7%

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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31. Alternative performance measures continued
B. Free cash flow

E. See-through Income Statement

Reconciliation of free cash flow

Cash generated from operations (note 25)

Interest payable and similar charges

Capital expenditure

Tax paid

Free cash flow

C. Net debt

Reconciliation of net debt

Loans and borrowings – non-current

Cash and cash equivalents

Net debt

D. Underlying effective tax rate

Reconciliation of underlying effective tax rate

Total taxation charge for the year

Non-underlying tax debit/(credit) (note 5)

Underlying taxation charge for the year 

Underlying profit before tax for the year

Underlying effective tax rate

Year ended  
31 December 2022
£000s

Year ended  
31 December 2021
£000s

24,929 

(4,804)

(407)

(3,957)

15,761 

44,919 

(2,965)

(5,532)

(6,260)

30,162

Note

(18)

(16)

31 December 2022
£000s

31 December 2021
£000s

(133,744)

31,714 

(102,030)

(116,060)

29,061 

(86,999)

Year ended  
31 December 2022
£000s

Year ended  
31 December 2021
£000s

(4,272)

(2,962)

(7,234)

30,311

23.9%

(10,838)

2,805

(8,033)

42,218

19.0%

Revenue – Consumer Healthcare 
brands

Revenue – Prescription Medicines

Total revenue 

Cost of sales

Gross profit

Gross profit margin

Revenue – Consumer Healthcare brands

Revenue – Prescription Medicines

Total revenue 

Cost of sales

Gross profit

Gross profit margin

2022  
Statutory 
 values 
£000s

120,622 

46,794 

167,416 

(65,733)

101,683 

60.7%

2021  
Statutory 
 values 
£000s

115,376 

47,831 

163,207

(53,757)

109,450

67.1%

See-through  
adjustment 
£000s

4,594 

–   

4,594 

(4,594)

–   

–

See-through  
adjustment 
£000s

6,443

–

6,443

(6,443)

–

–

2022  
See-through  
values
 £000s

125,216 

46,794 

172,010 

(70,327)

101,683 

59.1%

2021  
See-through  
values
 £000s

121,819 

47,831 

169,650

(60,200)

109,450

64.5%

There is no impact from the see-through adjustment on Income Statement lines below 
gross profit. 

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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31. Alternative performance measures continued
F. Constant exchange rate revenue

LFL see-through revenue – Consumer  
Healthcare brands

LFL see-through revenue – Prescription 
Medicines

Like-for-like see-through revenue

Impact of acquisitions (ScarAway™ and 
Kelo-Cote™ US)

See-through revenue (Note E)

LFL statutory revenue – Consumer  
Healthcare brands

LFL statutory revenue – Prescription 
Medicines

Like-for-like statutory revenue

Impact of acquisitions ( (ScarAway™ and 
Kelo-Cote™ US

Statutory revenue

2022 
AER
£000s

Foreign  
exchange  
impact 
£000s

2022  
CER 
 £000s

118,883 

(5,994)

112,889 

46,794 

165,677 

6,333 

172,010 

95 

46,889 

(5,899)

159,778

(774)

5,559

(6,673)

165,337 

2022 
AER
£000s

Foreign  
exchange  
impact 
£000s

2022 
CER 
 £000s

114,289 

(5,994)

108,295

46,794 

161,083 

6,333 

167,416 

95 

46,889 

(5,899)

155,184

(774)

5,559

(6,673)

160,743 

Financial Statements
Independent Auditor’s Report 

Consolidated Income Statement 

 Consolidated Statement of  
Comprehensive Income 

Consolidated Balance Sheet 

Company Balance Sheet 

Consolidated Statement of  
Changes in Equity 

Company Statement of  
Changes in Equity 

Consolidated and Company Cash  
Flow Statements 

93

102

103

104

105

106

107

108

Notes to the Financial Statements  109

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Alliance Pharma plc Annual Report and Accounts 2022

Additional 
Information

Additional Information
Unaudited Information 

148

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

149

150

151

152

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U N A U D I T E D   I N F O R M A T I O N

Unaudited information

Shareholder information
Shareholder enquiries
The Company’s share register is maintained by Link Group (‘Link’) who are 
responsible for updating the register, including changes to shareholders’ names  
or addresses and processing off-market transfers of the Company’s shares.  
If you have any question about your shareholding in the Company or you need  
to notify any changes to your personal details you should write to Link Group,  
10th Floor, Central Square, 29 Wellington Street, Leeds, LS1 4DL or telephone 
0371 664 0300 (calls are charged at the standard geographical rate and will 
vary by provider, lines are open 9.00am to 5.00pm Monday to Friday). 

Financial Calendar
Annual General Meeting 

25 May 2023

Interim results announcement 

19 September 2023

Year end 

31 December 2023

Preliminary announcement 

19 March 2024

Additional Information
Unaudited Information 

148

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

149

150

151

152

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F I V E   Y E A R   S U M M A R Y

Revenue

Operating profit before non-underlying items

Non-underlying operating items

Operating profit 

Profit before tax before non-underlying items

Profit before tax after non-underlying items

Intangible assets

Tangible assets

Current assets

Current liabilities

Equity

Average shares in issue (millions)

Shares in issue at period end (millions)

Earnings per share – basic (p)

Earnings per share – adjusted underlying basic (p)

Year ended 
 31 December 2018
£m 

Year ended 
 31 December 2019
£m

Year ended 
 31 December 2020
£m

Year ended 
 31 December 2021
£m

Year ended 
 31 December 2022
£m

118.2

28.9

(5.3)

23.7

28.1

22.8

335.2

7.6

58.7

91.7

252.2

497.2

518.2

3.69

4.54

135.6

37.4

(1.8)

35.6

32.9

31.1

328.7

11.6

65.0

24.2

274.2

520.7

529.4

4.80

5.09

129.8

36.8

(20.5)

16.3

33.5

13.0

412.9

15.9

77.2

30.2

281.0

531.1

532.9

1.51

5.11

163.2

45.6

(24.0)

21.6

42.2

18.2

413.8

4.8

81.0

40.6

282.5

535.3

538.2

1.37

6.39

167.4

35.7

(25.1)

10.6

30.3

5.2

421.6

5.6

105.5

47.0

287.7

539.5

540.0

0.17

4.28

Additional Information
Unaudited Information 

148

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

149

150

151

152

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A D V I S E R S   A N D   K E Y   S E R V I C E   P R O V I D E R S

Registered Office
Avonbridge House 
Bath Road 
Chippenham 
Wiltshire 
SN15 2BB

Company number
04241478

Auditor
Deloitte LLP
3 Rivergate 
Temple Quay 
Bristol  
BS1 6GD

Financial PR
Buchanan Communications
107 Cheapside 
London  
EC2V 6DN

Registrars
Link Group
10th Floor 
Central Square 
29 Wellington Street 
Leeds 
LS1 4DL

Nomad and Joint Broker
Numis Securities Limited
45 Gresham Street 
London  
EC2V 7BF

Joint Broker
Investec Bank plc
2 Gresham Street 
London 
EC2V 7QP

Bankers
Bank of Ireland
Bow Bells House 
1 Bread Street 
London EC4M 9BE

Citibank, N.A
Citigroup Centre 
33 Canada Square 
Canary Wharf 
London E14 5LB

Lloyds Bank PLC
25 Gresham Street 
London EC2V 7HN

National Westminster Bank PLC
250 Bishopsgate 
London EC2M 4AA

Silicon Valley Bank
Alphabeta 
14–18 Finsbury Square 
London EC2A 1BR

Additional Information
Unaudited Information 

148

Five Year Summary 

149

 Advisers and Key Service Providers 150

 Cautionary Statement 

Glossary 

151

152

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The Report of the Directors in this Annual Report has been drawn 
up and presented in accordance with English company law and 
the liabilities of the Directors in connection with that report shall 
be subject to the limitations and restrictions provided by such law. 

In particular, Directors would be liable to the Company (but not 
to any third party) if the Report of the Directors contains errors 
as a result of recklessness or knowing misstatement or dishonest 
concealment of a material fact, but would not otherwise  
be liable.

 C A U T I O N A R Y   S T A T E M E N T

Cautionary statement regarding forward-looking 
statements
This Annual Report has been prepared for the members of 
the Company and no one else. The Company, its Directors, 
employees or agents do not accept or assume responsibility to 
any other person in connection with this document and any such 
responsibility or liability is expressly disclaimed.

This Annual Report contains certain forward-looking statements 
with respect to the principal risks and uncertainties facing 
Alliance. By their nature, these statements and forecasts involve 
risk and uncertainty because they relate to events and depend 
on circumstances that may or may not occur in the future. 
There are a number of factors that could cause actual results or 
developments to differ materially from those expressed or implied 
by these forward-looking statements and forecasts. The forward-
looking statements reflect the knowledge and information 
available at the date of preparation of this Annual Report, and 
will not be updated during the year. Nothing in this Annual 
Report should be construed as a profit forecast.

Additional Information
Unaudited Information 

148

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

149

150

151

152

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

152

G L O S S A R Y

AGM 

APAC

B2B

B2C

CBEC 

CEO 

CFO 

CMA 

CMO 

EMEA

ERP 

ESG 

Annual General Meeting

Asia Pacific and China

Business-to-business

Business-to-consumer

Cross-border e-commerce

Chief Executive Officer

Chief Finance Officer

Competition and Markets Authority

Contract manufacturer

Europe, Middle East and Africa

Enterprise resource planning

Environmental, Social, and Governance

GPTW® Great Place To Work

HCP 

I&D

IHP 

J&J 

LSP 

NED

OTC 

SECR 

TCFD 

Healthcare professional

Innovation and development

International Health Partners

Johnson & Johnson

Logistics service provider

Non-executive Director

Over the counter

Streamlined Energy and Carbon Reporting regulations

Task Force on Climate-related Financial Disclosures

Additional Information
Unaudited Information 

148

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

149

150

151

152

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

153

Additional Information
Unaudited Information 

138

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

139

140

141

142

For more information visit  
alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022Alliance Pharma plc Annual Report and Accounts 2022Additional Information
Unaudited Information 

148

Five Year Summary 

 Advisers and Key Service Providers 

 Cautionary Statement 

Glossary 

149

150

151

152

Alliance Pharma plc 

For more information visit  
alliancepharmaceuticals.com

Avonbridge House, Bath Road, Chippenham, Wiltshire, SN15 2BB, United Kingdom 
T: +44 (0)1249 466966 F: +44 (0)1249 466977 E: ir@alliancepharmaceuticals.com  
www.alliancepharmaceuticals.com

Alliance Pharma plcAnnual Report and Accounts 2022