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Alliance Pharma

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FY2021 Annual Report · Alliance Pharma
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Alliance Pharma plc  
Annual Report and Accounts  
2021

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

An alliance of people, 
partners and brands, 
working together  
to achieve more

Contents

Company Overview
2021 Financial Highlights

At a Glance

Our Values

01

02

04

Strategic Report

 Chief Executive’s Review

Our Markets

Our Business Model

 Our Strategy

Key Performance Indicators

Sustainability Overview

Sustainability Performance

Developing our Environmental  
Sustainability Strategy

Stakeholder Engagement

Financial Review

 Principal Risks and Uncertainties

Governance

Chairman’s Introduction

Board of Directors 

Governance

Nomination Committee Report

Audit and Risk Committee Report

Remuneration Committee Report

ESG Committee Report

Task Force on Climate-related Financial 
Disclosures (TCFD)

Directors’ Report

47

48

50

56

60

65

76

78

80

Financial Statements

Independent Auditor’s Report

 Consolidated Income Statement

 Consolidated Statement of 
Comprehensive Income

Consolidated Balance Sheet

Company Balance Sheet

 Consolidated Statement of Changes 
in Equity

 Company Statement of Changes in Equity

 Consolidated and Company Cash 
Flow Statements

Notes to the Financial Statements

86

95

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100

101

102

07

13

16

17

23

25

28

33

34

35

39

Additional Information

Unaudited Information

Five Year Summary

 Advisers and Key Service Providers

 Cautionary Statement

Glossary

139

140

141

142

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Alliance Pharma plc – Annual Report and Accounts 2021

For more information visit  
alliancepharmaceuticals.com

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

2021 Financial Highlights

The Group delivered a 
strong operational and 
financial performance 
in 2021, leaving it well 
placed to take advantage 
of further growth 
opportunities in 2022.

See-through Revenue*

Statutory Revenue

Underlying Profit Before Tax

£169.6m +23%

£163.2m +26%

£42.2m +26%

(2020: £137.5m)

(2020: £129.8m)

(2020: £33.5m)

Reported Profit Before Tax

Underlying Basic EPS

£18.2m +40%

6.39p +25% 

Reported Basic EPS

1.37p -9%

(2020: 1.51p)

(2020: 5.11p)

Net Debt*

(2020: £13.0m)

Free Cash Flow*

£30.2m -12%

(2020: £34.1m)

Overview

£87.0m -20%

(2020: £109.4m)

* 

 Non-IFRS alternative performance measures (see note 34).  
See-through revenue includes all sales from Nizoral as if they had 
been invoiced by Alliance as principal. For statutory accounting 
purposes the product margin relating to Nizoral sales made on an 
agency basis is included within Revenue, in line with IFRS 15.

     Strong overall revenue growth driven by 

      Strong Free Cash Flow* driving down Group 

      Dedicated Innovation and Development team 

Consumer Healthcare, underpinned by continued 
market penetration via e-commerce activity, which 
now represents around 25% of Group sales

   Consumer Healthcare see-through revenue* up 
31% to £121.8m (2020: £93.0m) and up 36% 
at constant exchange rates* (CER) with excellent 
performance from Kelo-cote and the inclusion of 
Amberen, acquired in December 2020

   Robust Prescription Medicines performance with 
revenues up 8% to £47.8m (2020: £44.5m), 
with strong H2 recovery as the effects of 
COVID-19 receded

leverage to 1.7x at 31 December 2021 (2.4x at 
December 2020)

now in place to underpin Consumer Healthcare 
organic growth

      Amberen fully integrated into the Group

     Roll-out of strategic brand plan for Nizoral now  

      Successfully implemented Group-wide ERP 

well underway

system, enhancing visibility across the business

      Committed to carbon neutral Scope 1&2 

      US operating capabilities expanded to provide 

a platform for future growth

    Strengthened European management team 
and expanded the Board to increase consumer 
brand experience

emissions from 2021

      Certified as a Great Place To Work® again in 
UK and China, and now in Singapore with a 
Trust Index© rating of 76%

01

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

At a Glance

We are Alliance,  
a growing international  
healthcare group

Headquartered in 
the UK, we employ 
around 250 people 
based in locations 
across Europe,  
North America, 
and the Asia 
Pacific region. 

Who we are 
We are Alliance, a growing international 
healthcare group.

A business founded on the principle that  
by working together, we can achieve more.

What we do 
Our purpose is to improve the lives of 
consumers and patients through making 
available a range of clinically valuable 
healthcare products.

How we do it 
Every day, we work with our partners and 
colleagues around the globe, to maximise  
the value of our brands.

Confident in the knowledge that in doing so,  
we can make a real difference to people’s lives.

Our core business is Consumer Healthcare.  
This accounts for more than 70% of our revenues 
and is what drives our growth. We also have a 
well-established Prescription Medicines business, 
which operates from the same regulatory platform. 
In total, we hold marketing rights to around 
80 brands.

Our commercial operations extend across EMEA, 
AMER and APAC, with revenues generated from 
a mix of direct, distributor and e-commerce sales. 
By outsourcing all our manufacturing and logistics 
activities, we remain asset-light and focused on 
maximising the value of our brands.

02

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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At a Glance continued

Our Purpose

Our Vision

Our Strategy

To improve the lives of consumers and patients 
through making available a range of clinically 
valuable healthcare products.

To be a leading international healthcare 
business, built around products that are 
clinically valuable to patients. 

We will be both the partner and employer 
of choice.

There are two main strands to our strategy:

   Delivering solid organic growth from 
our key brands

    Supplementing this growth with 
selective, complementary acquisitions  
in the consumer healthcare space

Underpinned by a focus on:

   Investing in people

   Sustainability

See page 17

Our Business Model 

Our Culture

Our Values

Leveraging the global platform we’ve 
created and the capabilities, expertise and 
relationships that support this enables us to 
maximise the value of our existing brands and 
integrate acquired brands with ease.

Our culture reflects the spirit of collaboration 
embedded in our business – the tacit belief that 
through working together, both internally and 
with external partners, we can achieve more 
for our stakeholders and for society as a whole. 

   Performance 

   Realism 

   Accountability 

    Integrity 

    Skill

    Entrepreneurship

See page 16

See page 22

See pages 04 & 05

03

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

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Our Values

Living up to  
our values

Acting in accordance with our 
values, we maintain our strong 
culture of working together to 
achieve more.

Realism 

We set stretching goals and targets which  
we believe are achievable

When we learnt that the manufacturer of one 
of the lead products in our Vamousse headlice 
prevention/treatment range was unable to 
continue manufacturing it, some quick thinking 
was needed to avoid a potential out of stock 
situation in the peak back-to-school season in 
the US. By working together and adopting a 
creative, ‘can do’ approach, a cross-functional 
team, with participants from the US and UK, 
managed to come up with a solution which, with 
limited compromises and last-minute adjustments, 

they then successfully implemented to resolve 
what had originally looked like a very 
challenging situation.

Performance 
Our high-performing people continually 
drive business success

Undeterred by the challenges of remote 
working imposed by the global pandemic, 
in April 2021, members of our global 
brand marketing team went above and 
beyond to deliver a very successful 
Alliance brand week and marketing 
excellence program virtually. This enabled 
the brand leads to showcase the plans 
they’d created for each of the 13 brands 
prioritised as part of this programme, 
building wider awareness and 
understanding of our brand marketing 
priorities across the business.

See page 22

Accountability 
We take responsibility and deliver what  
we promise

From developing new Key Opinion Leaders’ 
endorsements for our products to delivering 
new or improved processes, many great 
demonstrations of our values in practice 
involve our employees taking individual 
or collective responsibility to ensure that 
delivery expectations are met at all levels in 
the organisation. One of the best examples 
of Accountability in 2021 came from our UK 
Facilities team, who successfully managed 
the transformation of our UK headquarters 
and the challenge of undertaking works to a 
listed building, against the backdrop of ever-
changing COVID-19 restrictions.

See page 33

04

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Our Values continued

   Our values, and the culture that underpins them,  
are at the heart of how we operate as a business

   Each month, we take time to celebrate outstanding 
demonstrations of our values in practice

   In 2021, more than 50 colleagues received special 
recognition through the values-based PRAISE awards 
scheme, with more than £2,500 donated to charities 
of their choice

Skill 

We recruit highly skilled people and develop 
their talents to the full

Many of our PRAISE awards recognised the 
utilisation of skills developed over the course 
of an employee’s journey with Alliance – we 
see many great examples of employees taking 
on and successfully delivering projects that lie 
outside their current experience and skill sets. 

Integrity
We build trust in all our relationships

Trust is a key element in all our relationships, 
both internal and external – creating successful 
partnerships and business relationships 
depends on it. In April 2021, after a lengthy 
process, members of our medical and 
regulatory teams successfully obtained a 
new indication for one of our established 
Prescription Medicines in the UK and 10 other 
territories across the EU. To do this, they had to 
overcome multiple challenges – from dealing 
with several complex information requests from 
the assessors to translation issues and rigorous 
challenges from our safety partners. Through 
exercising a high degree of skill and integrity, 
showing sensitivity to others’ perspectives, and 
persevering with their endeavours, the team 
successfully delivered a great outcome, both 
for Alliance and for patients.

For example, in 2021 a member of our 
customer services team took on the challenge 
of consolidating the business activities going 
through our two UK wholesalers – the first 
project of this size and cross-functional nature 
they had led. Through effective leadership 
and strong project management skills, they 
were able to bring the project to a successful 
conclusion and enable the associated cost 
savings to be realised.

The ‘Alliance Asset Hub’, an enterprising solution 
conceived and actualised by a member of our 
global marketing team, now sits at the heart of our 
marketing ecosystem, providing a single source 
of truth for all our digital brand assets. Accessible 
by teams around the globe and with the ability to 
make direct updates to our brand websites, whilst 
controlling access and usage rights, the system is 
expected to deliver real business benefits as our 
focus on marketing excellence continues.

05

Entrepreneurship 
Our people think of the business as it if was their own

Tired of the daily frustration of trying to 
locate the right brand assets, our marketing 
team came together and decided to take the 
initiative to create a digital asset management 
system to better manage our growing 
portfolio of digital assets.

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Strategic 
Report

 Chief Executive’s Review

Our Markets

Our Business Model

 Our Strategy

Key Performance Indicators

Sustainability Overview

Sustainability Performance

Developing our Environmental  
Sustainability Strategy

Stakeholder Engagement

Financial Review

 Principal Risks and Uncertainties

07

13

16

17

23

25

28

33

34

35

39

06

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Chief Executive’s Review  

Continuing  
on our growth 
trajectory  

See-through Revenue*

£169.6m +23%

(2020: £137.5m)

Statutory Revenue

£163.2m +26%

(2020: £129.8m)

* 

 Non-IFRS alternative performance measures (see note 34).  
See-through revenue includes all sales from Nizoral as if they had 
been invoiced by Alliance as principal. For statutory accounting 
purposes the product margin relating to Nizoral sales made on an 
agency basis is included within Revenue, in line with IFRS 15.

“ I’m delighted with the strong 
performance of the Group in 
2021. Kelo-cote enjoyed another 
excellent year, helping us to 
deliver double digit organic 
revenue growth, and Amberen 
is now fully integrated into our 
enlarged US operations”

Alliance Pharma plc – Annual Report and Accounts 2021

07

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Chief Executive’s Review continued

TRADING PERFORMANCE
Overview
The Group delivered strong growth in the year, 
with see-through revenue up 23% to £169.6m 
(2020: £137.5m), despite the impact of currency 
headwinds and continuing lockdowns, particularly 
in the APAC region; at constant exchange rates 
(CER), revenue growth was 27%. Like-for-like 
(LFL) revenue, excluding revenues attributable to 
Amberen, which was acquired by the Group at the 
end of 2020, grew 9% (12% CER). On a statutory 
reported basis, Group revenues were up 26% to 
£163.2m (2020: £129.8m) (+30% CER) and up 
11% to £144.0m (2020: £129.8m) on a like-for-
like basis, excluding Amberen (+14% CER).

Gross profit increased by 32% to £109.5m (2020: 
£82.8m), the increase outstripping revenue 
growth due to favourable changes in product 
mix, resulting from the inclusion of Amberen 
and the significant growth in Kelo-cote sales. 
This was balanced by an expected increase in 
operating costs, primarily reflecting the inclusion 
of the Amberen cost base, the resumption of 
discretionary spend deferred from the early stages 
of the pandemic and higher levels of investment 
in the business to support growth. Coupled with a 
small increase in depreciation and amortisation 
charges, as we brought our new ERP system into 
service, underlying profit before tax increased 
26% to £42.2m (2020: £33.5m), with the profit 
before tax margin increasing by 50 basis points to 
24.9% (2020: 24.2%). 

Non-cash amortisation and impairment charges, 
together with a provision in relation to the 
Competition and Markets Authority (CMA) 
decision and restructuring costs, resulted in 
reported profit increasing by 39% to £18.2m 
(2020: £13.0m).

Consumer Healthcare
Our Consumer Healthcare business continued 
to perform well through 2021, with increased 
e-commerce activity and the integration of Amberen
helping to drive year-on-year see-through revenue 
growth of 31% (36% CER), to £121.8m (2020: 
£93.0m). On a statutory basis, reported revenues 
were £115.4m, up 35% from the previous year 
(2020: £85.3m) and up 41% CER.

Excluding the impact of Amberen, like-for-like 
Consumer Healthcare see-through revenue 
increased by 10% (14% CER) to £102.6m whilst 
reported revenue increased by 13% (16% CER)  
to £96.1m. 

Kelo-cote – scar prevention & treatment
Kelo-cote delivered another excellent performance, 
particularly in the APAC region, generating revenues 
of £48.8m, up 41% on the prior year (2020: 
£34.7m). CER revenues were up 47% due to 
continued strong demand from China, reflecting the 
growth of both domestic sales and significant cross-
border e-commerce (‘CBEC’) sales.

Kelo-cote is very well established in China, with high 
brand awareness and usage. The growth in domestic 
and CBEC revenues reflects the increasing trend for 
consumers in China and elsewhere to migrate more 
to online purchasing, both of the brand itself and 
healthcare products generally – a trend accelerated 
by the pandemic.

In 2021, we entered into a new CBEC distribution 
agreement for Kelo-cote, to move Alliance closer 
to the customer and provide greater control of 
our distribution chain. This decision was taken in 
response to the success of CBEC in facilitating export 
sales from the EU to consumers in China, and in 
recognition of the significant opportunity that China 
offers for this key brand. As a result, we expect further 
top-line growth in China over the medium term.

Performance across the rest of the APAC region 
was more mixed, as many countries continued to 
be impacted by the pandemic, although both Hong 
Kong and South Korea recorded strong growth. 
A similar trend was evident across South America 
and much of EMEA; with strong performances from 
a number of European territories including France 
(domestic and export sales), and the UK.

* 

 See-through revenue includes all sales from Nizoral as if they had been
invoiced by Alliance as principal. For statutory accounting purposes 
the product margin relating to Nizoral sales made on an agency basis 
is included within Revenue, in line with IFRS 15.

08

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Chief Executive’s Review continued

Amberen – vitamin mineral  
supplement for the relief of  
menopause symptoms (US)
Amberen made an encouraging start during its 
first year of trading under the Group’s ownership, 
generating net revenues of $26.5m (£19.2m) in the 
Year, with H2 2021 revenues up 12% CER on H2 
2020 (under previous ownership). Full year revenue 
growth was up 3% CER, with the brand’s Amazon 
sales in particular experiencing strong year-on-year 
growth, compensating for more challenging trading 
conditions for the category as a whole in the bricks 
and mortar retail sector. 

We expect to see Amberen revenue growth 
accelerate in 2022, with a weighting towards H2, 
as we look to leverage the expanded operating 
platform we have put in place in the US, increase 
our focus on brand positioning and execute a new 
integrated marketing campaign for the brand. 

We are focused on developing an innovation 
pipeline to underpin the growth of the brand in the 
longer term.

Nizoral – medicated  
anti-dandruff shampoo
Nizoral had a challenging start to the year due 
to a combination of distributor order phasing, 
manufacturing delays, and the ongoing impacts 
of COVID-19 on demand, particularly in India. 
We experienced some delay to the transitioning of 
regulatory approvals in Vietnam and the Philippines, 
whilst growth in key pharmacy chain listings for the 
new Triatop combi product in China was also slower 
than planned.

However, revenues started to recover in the second 
half of the year, with see-through revenue of £11.6m 
in H2 2021 (£9.0m in H1 2021 and £11.2m in 
H2 2020), as the challenging regional trading 
conditions affecting both supply and demand eased. 
Triatop combi product pharmacy listings in China 
also improved in the last few weeks of the year, which 
should help support further sales momentum in 2022. 
Consequently, see-through revenues for the Year of 
£20.6m, were up 1% CER (-2% as reported) (2020: 
£21.0m). On a statutory reported basis, revenues 
were up 7%, at £14.2m (2020: £13.3m) (+9% CER).

We expect to see further improvement in 2022, as 
the pandemic recedes and we take full control of 
the supply chain following the end of the transition 
period with J&J. The roll-out of our strategic brand 
plan for Nizoral is now well underway, with 
consumer activation campaigns ongoing or planned 
across a number of key territories, including Australia, 
South Korea and Taiwan. These activities are being 
carried out in partnership with our local distribution 
partners as part of a growth strategy centred around 
consumer and healthcare professional activation, 
e-commerce, and Innovation & Development (I&D). 

Other Consumer Healthcare brands
We continued to see a mixed performance across 
our other Consumer Healthcare brands, particularly 
for those products sold principally through 
international distributors.

MacuShield (eye health supplement), was an 
early beneficiary of a recovery in UK retail sales 
post COVID-19, whilst Vamousse (prevention and 
treatment of head lice) continued to be impacted by 
COVID-19 challenges as school closures and social 
distancing requirements led to significantly reduced 
incidence of head lice, particularly in the US, the 
product’s primary market. With distributor stocking 
patterns contributing to declines in Oxyplastine and 
Aloclair, revenues in other Consumer Healthcare 
brands fell 9% CER.

As we progress through 2022, and global trading 
patterns and consumer behaviours start to normalise 
post COVID-19, we expect to see sales of Vamousse, 
Aloclair, Oxyplastine and a number of our other 
smaller consumer brands start to pick up again. 
Further revenue detail on these brands is available 
in note 3.

Prescription Medicines
The Prescription Medicines business delivered robust 
revenues of £47.8m (2020: £44.5m), up 8% on the 
prior year, reflecting a partial return to the delivery 
of routine treatments and normalisation of daily life 
compared with the early stages of the pandemic 
in 2020. Key drivers of revenue growth included 
the Opus range of stoma care products, Forceval 
(nutritional supplement), Hydromol (emollient for the 
treatment of eczema) and Flammazine (prevention of 
infection of burns and wounds).

We continue to actively manage this part of our 
portfolio, periodically discontinuing or disposing 
of smaller products that deliver very low sales and 
margins. However, the cash generation from these 
assets remains good and, coupled with their limited 
requirement for promotional investment, this business 
will continue to play an important part in our overall 
product portfolio.

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AMER (The Americas)
Revenues in the AMER region increased by £19.3m 
to £26.0m (2020: £6.7m), reflecting the acquisition 
of Amberen, which contributed £19.2m to sales in 
the year. On a like-for-like basis, sales were in line 
with those for the prior year at £6.8m, with a decline 
in Vamousse sales in the US, due to the continued 
impacts of the pandemic, offset by increased sales 
of Kelo-cote in South America. This region now 
accounts for more than 20% of our Consumer 
Healthcare revenues.

Following a period of investment to expand its 
local operating capabilities, the US business now 
has an enhanced platform from which to generate 
strong growth in Amberen and other existing brands 
and to scale up further when suitable acquisitions 
are identified.

Chief Executive’s Review continued

Regional performance
EMEA (Europe, UK, Middle East & Africa)
EMEA regional revenues of £89.2m were down 
5% versus those for the prior year (2020: £93.8m), 
primarily due to a mid-year change in the distributor 
for Kelo-cote CBEC, which is now located in APAC, 
and hence sales are now included in APAC revenues, 
whereas previously they were included in EMEA. This 
change in revenue classification was partially offset 
by the uplift in Prescription Medicines revenues, with 
this region accounting for 95% of all Prescription 
Medicines sales in the year, coupled with the growth 
in MacuShield sales, which originate primarily in 
EMEA (the largest market being the UK). 

APAC (Asia Pacific and China)
APAC regional see-through revenues rose 47%  
versus the prior year at £54.4m (2020: £37.0m),  
with statutory revenues up 64% to £48.0m  
(2020: £29.3m).

Revenues in this region are dominated by Kelo-cote 
and Nizoral (which is only sold by Alliance in APAC) 
and which collectively account for 90% of APAC 
sales in 2021.

Regional revenues in 2021 benefitted from the 
change in distribution arrangements for Kelo-cote 
CBEC sales, with revenue recognised as part of 
APAC, rather than EMEA, from the middle of the 
year. The uplift in sales also reflects underlying 
growth in Kelo-cote sales, both in China and across 
the wider APAC region, coupled with the slight 
decline in Nizoral sales. 

Developing our regional platform 
Rounding out our operational capabilities across 
the three geographic regions in which we operate, 
EMEA, APAC and AMER, has been a major focus 
for us in recent years. The platform which we’ve 
created across these three regions, underpinned 
by our global support functions, enables us to 
create value through both driving the growth of our 
existing brands and acquiring and integrating new 
assets with ease – as demonstrated most recently 
with Amberen.

CURRENT TRADING AND OUTLOOK 
2022 has started well, and we remain confident in 
our ability to deliver financial performance in line 
with market expectations.

We now have a clear focus on our core Consumer 
Healthcare business, supported by a well-defined 
value maximisation strategy and a scalable 
platform across EMEA, APAC and the US,  
to drive future growth.

The new distribution agreement we put in place in 
2021 will enable us to deliver further growth for 
Kelo-cote through our CBEC business and gives 
us the opportunity to extend the range of products 
made available through this channel, potentially 
accelerating the growth of a number of our other 
consumer brands.

Through 2022, we expect to see increased growth 
from Nizoral as we accelerate the roll-out of our 
strategic plan for the brand and as the impact of the 
pandemic recedes.

With Amberen now fully integrated into our enlarged 
US operations, we expect to see revenues increasing 
as we begin to realise the benefits of additional 
revenue opportunities that the brand has brought into 
the Group.

We now have a more balanced consumer portfolio 
around the globe and, as our net debt and leverage 
continue to reduce, we are increasingly well placed 
to participate in complementary acquisitions in the 
consumer healthcare space and to leverage the 
operating platform we have built across EMEA, 
APAC and the US. Coupled with a proven ability 
to extract value from our key consumer brands, we 
remain confident in our ability to realise our mid-
term growth ambitions.

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Chief Executive’s Review continued

OPERATIONAL DEVELOPMENTS
We recognise the need to invest in our business 
to maintain strong organic revenue growth. 
We recently implemented a new Innovation & 
Development (I&D) process and in 2021 we created 
new dedicated roles and a central I&D budget to 
deliver new products, claims and packaging ideas. 
We expect to see a number of these innovations 
come to market in 2022 as we refresh existing 
products to maintain consumer appeal.

We have also commenced the roll-out of our 
new Digital Excellence training programme to 
our global marketing teams to ensure our staff 
have the necessary skills and knowledge to drive 
sustainable long-term value.

Our ERP system went live in the first half of 2021, 
and we have already realised benefits to the 
business through the standardisation of processes. 
Our significant pre-launch preparation ensured a 
virtually seamless changeover; work continues on 
refining some of the reporting requirements and 
rolling the system out to a few remaining smaller 
entities, but we expect this to complete in the next 
12 months.

During the year we secured new, larger offices 
in Cary, North Carolina, to accommodate our 
growing US team, closed our office in Los Angeles 
and streamlined our European footprint through  
the closure of our Milan office, incurring  
associated restructuring costs of £2.4m, which  
have been presented as non-underlying.  

We also completed further substantial upgrade 
and refurbishment works at our UK headquarters, 
improving the building’s environmental 
credentials whilst also reconfiguring space to 
better accommodate post-pandemic working 
arrangements. All employees have now returned 
to the office on a hybrid basis, both in the UK 
and in our regional offices around the globe, as 
pandemic restrictions allow.

INCREASING OUR FOCUS ON 
SUSTAINABILITY
We have continued to focus on developing our 
sustainable business strategy during the year, 
under the direction of the ESG Board Committee, 
and informed by feedback from a number of 
our key investors plus external gap analysis. 
This work has resulted in the development of our 
Sustainability Framework; we now have greater 
clarity regarding our specific areas of focus and 
the key activities which underpin these.

We have initiated a programme of work to drive 
improvements to the sustainability of our product 
packaging and are also in the early stages of 
developing our broader environmental strategy, 
including our response to climate change. In 
2021, we quantified our Scope 3 greenhouse 
gas emissions for the first time and are using the 
results to help inform the development of our 
carbon action plan, with a view to setting carbon 
reduction targets and our path to net zero in the 
near future.

Minimising our environmental impact 
In 2021, we completed a programme of upgrading 
and refurbishment works at our UK headquarters, 
further improving the building’s environmental 
credentials. We continue to actively look for ways 
to reduce our direct (Scope 1 & 2) emissions as part 
of the drive towards net zero and intend to achieve 
carbon neutrality for our Scope 1 & 2 UK emissions 
for 2021 retrospectively in 2022, through the use of 
sequestration schemes.

Given the nature of our business, and our use of 
third-party distributors, contract manufacturers 
(CMOs) and logistics service providers (LSPs), 
the majority of our greenhouse gas emissions 
are classified as Scope 3. In 2022, we plan to 
reach out to our larger CMOs and LSPs to better 
understand where they are on their respective 
emissions reduction journeys and to obtain 
their Scope 1 and 2 data to help improve the 
methodology used for our Scope 3 calculations. 
We will also continue to reduce our own Scope 
1 and 2 emissions, which were 90tCO2e for our 
UK operations in 2021, and will achieve carbon 
neutrality for these retrospectively in 2022 through 
the use of sequestration schemes.

With the foundations now in place, we will be 
looking to raise the profile of sustainability within 
the business more widely in 2022, as we continue 
our journey to become a more sustainable 
business. We remain a responsible corporate 
citizen, committed to minimising the negative 
impacts of our operations on the environment, 
whilst making a positive contribution to society.

Further coverage on the progress we have made 
with our sustainable business strategy can be 
found on pages 25 to 33 of this report.

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Chief Executive’s Review continued

PEOPLE
On behalf of the Board, I would like to take this 
opportunity to express my sincere thanks to all 
those who have helped to make 2021 such a 
successful year for Alliance. We currently employ 
around 250 people in 10 locations around the 
globe. In 2021, we created around 20 new roles, 
spread across all our main geographic locations, 
as we looked to meet our evolving business needs. 
This included the creation of a new dedicated 
I&D team to underpin the growth of our Consumer 
Healthcare brands.

We recognise the need to develop appropriate in-
house expertise in specific skill sets, using a blend 
of external subject matter experts and internal 
training to ensure our platform remains scalable 
as we grow. We anticipate continued investment in 
our global team in 2022.

In 2021, we once again participated in the Great 
Place To Work® survey, as we further progressed 
our employee engagement journey. We were very 
pleased to have received an overall Trust Index© 
rating of 76% and to have been recertified as a 
Great Place To Work® in the UK and China whilst 
gaining an additional certification in Singapore, 
with 81% of participants globally saying that 
Alliance was a Great Place To Work®.

Further coverage on this and other aspects of our 
people strategy can be found on page 22.

During the second half of the Year, we rolled 
out and refined our new ways of working to 
provide flexibility over office and home working 
for our employees around the globe, based on 
individual role, activities, and the location of other 
colleagues with whom they interact regularly. The 
majority of employees now spend 2 or 3 days a 
week in the office, subject to local government 
guidance, allowing them to combine the benefits 
of individual focus time with the increased 
connection and collaboration opportunities 
that come from being physically present with 
colleagues in the office. This increased flexibility 
has been very positively received across the 
business and is working well for us.

We recognise that great people, and the 
successful partnerships that they build both within 
the business and externally, are key to the delivery 
of great results. 

BOARD CHANGES
As previously announced, Kristof Neirynck, a 
highly experienced consumer brands executive, 
took up his position as an independent Non-
executive Director of the Group on 1 December 
2021, bringing with him almost 20 years of 
international consumer brand experience, 
including complex omnichannel business models, 
direct-to-consumer strategies and CBEC sales  
into China. His experience will be invaluable  
as we look to further develop and grow our 
business, in particular our CBEC activities,  
over the coming years.

Supporting early-stage career development  
2021 saw two of our employees successfully 
complete their apprenticeship training and move 
on to new permanent roles within the business – 
demonstrating the continued success of Alliance’s 
apprenticeship programme in fostering early-stage 
skills development. We have since taken on an 
additional apprentice in our Finance team and have 
recently launched both a graduate scheme and an 
industry placement scheme, furthering our commitment 
to supporting those at the start of their careers. 

LOOKING FORWARD TO 2022
2022 has got off to an encouraging start. We 
remain confident in our ability to further capitalise 
on identified organic growth opportunities within 
the business and to deliver financial performance 
in line with market expectations. 

Operationally, the priorities for the Group in  
2022 are:

 ›

 ›

 ›

To continue to invest behind our larger 
Consumer Healthcare brands, in order to drive 
further growth, supported by our increasing 
focus on e-commerce and I&D activities;

To continue to progress our sustainable 
business agenda, including the creation of our 
carbon action plan and the setting of emissions 
reduction targets;

To continue to look for opportunities to 
participate in complementary acquisitions in 
the consumer healthcare space, to leverage the 
operating platform we have built across EMEA, 
APAC and the US, and balance the scale of our 
business operations across these regions.

Peter Butterfield
Chief Executive Officer

30 March 2022

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Our Markets

The long-term trends in 
consumer healthcare remain 
unchanged, although the 
COVID-19 pandemic has 
caused significant short-term 
impacts. Sustainability is also 
emerging as a key consideration 
for both manufacturers and 
brand owners. 

1 in 20 Google searches 

relate to health

67% 

of people are 
researching  
health problems

60% 

59% 

tend to take an OTC 
product before making 
a doctors appointment

take OTC products 
to manage acute 
health conditions

Source: https://www.iqvia.com/-/media/iqvia/pdfs/library/fact-sheets/social-media-intelligence-brochure-for-consumer-health-customers.pdf

Macro trends in consumer healthcare
Increasing life expectancy – increasing 
 ›
longevity and ageing populations have 
led to an increased demand for healthcare 
– particularly for products which target 
conditions typically experienced in later life. 

 ›

Increasing prosperity, self-care, and the 
wellness movement – levels of prosperity 
and disposable income in many parts of the 
world, particularly in developing countries, 
are rising. We are also seeing a shift towards 
self-medication using over the counter (OTC) 
products, rather than relying on prescription 
medicines, coupled with an increased focus on 
personal wellbeing, and on prevention rather 
than cure.

 › Digital healthcare and the empowerment 
of patients and consumers – consumers, 
especially younger ones, are increasingly 
turning to online resources to self-diagnose 
and discover solutions to their health concerns. 
As prospective patients, consumers are 
becoming active partners in their healthcare 
journey. With the ability to carry out extensive 
research online, they are able to become more 
knowledgeable about the services they receive 
and the products they use.

 ›

The growth of e-commerce – the emergence 
of high-speed mobile data, rapid delivery times 
and increasingly secure and speedy payment 
methods have led consumers to embrace the 
convenience of online purchasing.

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Our Markets continued

Impacts of the COVID–19  
global pandemic
 ›

Fluctuating demand – consumers and 
retailers stocked up in the early stages of the 
pandemic, causing a subsequent reduction in 
demand and orders, impacting sales. Demand 
and supply patterns only normalise once 
inventory has sold through.

 › Strained supply chains – production and 

logistics have been heavily impacted both by 
workers being unable to work due to illness 
or self-isolation requirements, and reduced 
capacity as a result of compliance with social 
distancing restrictions.

 › New healthcare habits – consumers learnt 
to manage their minor ailments with home 
remedies or went without treatments, for 
example in the mouth ulcer category. Brands 
will need to re-engage with consumers about 
the benefits of treating, now that access to 
treatment is available again.

 › E-commerce – consumers switched to 

purchasing through online retailers, with global 
e-commerce sales increasing 26.4% in 2020 
and a further 16.3% in 2021. E-commerce 
now represents 19% of total retail sales, driven 
by the continued impact of the COVID-19 
pandemic shifting consumer purchase patterns 
from traditional bricks and mortar stores to 
online marketplaces like Amazon and retailer 
websites*. Consumers are expected to continue 
to shop this way. 

 › Self-diagnosis – consumers turned to the 
internet to diagnose their health issues and 
to find recommended solutions, relying less 
on healthcare professionals, who were often 
difficult to access.

Accelerated shifts towards 
digital healthcare

Emerging trends – sustainability 
Consumers, retailers, and healthcare providers 
are increasingly choosing goods and services that 
promote a lower carbon footprint compared to 
alternatives. As a result, organisations, consumer 
healthcare brands and their wider supplier 
network will need to demonstrate their commitment 
to the environmental agenda consistently and 
proactively in order to retain and grow their 
market positions.

E-commerce market is worth  4.9tr 
worldwide of which consumer healthcare is

260bn

Relevance of the online channel per CHC product category

Vitamins & supplements

Cold remedies

Pain killer

Cough relief

Wound care

Feminine hygiene1

Gastro-intestinal

Allergy

Eye care

Ear care

Heart health

Sedatives/sleeping aid

Lower online relevance

Average

Higher online relevance

Source: https://www.simon-kucher.com/en-gb/blog/online-shopping-consumer-healthcare-sector-what-consumers-want-and-what-deters-them

30%

growth in China and

23%

growth in the US in 2021

14

The opportunity for Alliance…
Alliance is very well-placed to meet the growing 
need for OTC and self-selection healthcare 
products and services, with over 70% of our 
revenues now generated from consumer 
healthcare products, and with our established 
global operating platform, strong distributor and 
retailer relationships, and an increasing focus both 
on product innovation and on sustainability.

* 

Source: e-Marketer, January 2022; InsiderIntelligence.com

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Our Markets continued

c.25%

of 2021 sales through 
e-commerce

…and how we’re capitalising on it
 › Our brand prioritisation framework ensures 
investment and innovation are focussed on 
the biggest perceived opportunities. In 2021, 
our key brand, Kelo-cote, delivered growth of 
more than 40%, driven by favourable category 
dynamics and the growing e-commerce 
channel, which now represents around 25% 
of Group sales. We have now put in place the 
brand strategies needed to accelerate growth 
of Nizoral and Amberen in 2022.

 ›

To support the growth of our e-commerce 
sales, in 2021 we set up a dedicated team to 
lead our cross-border e-commerce (‘CBEC’) 
activities and develop effective strategies to 
win in domestic e-commerce channels (see 
case study ‘Responding to the acceleration in 
e-commerce growth’ on page 20).

 ›

 ›

To further fuel the growth of our key and high-
priority brands, we introduced new innovation 
processes, tools and capabilities in 2021 
which have resulted in a rapid expansion of 
our consumer healthcare innovation pipeline. 
This will be further enhanced in 2022 by the 
creation of a dedicated team and a meaningful 
increase in the development budget, designed 
to deliver breakthrough new product extensions 
and claims for our key brands globally.

 › Our pharma heritage continues to provide 
us with a strong foundation, leaving us well 
placed to deal with the challenge of increased 
regulation that is now impacting consumer 
healthcare products – for example medical 
devices, which are currently facing increased 
regulation in Europe under the Medical Device 
Regulations. We continue to upskill our medical 
and regulatory capabilities to provide the 
necessary support.

The acceleration in digital healthcare provision 
and e-commerce has cemented the increasing 
importance of healthcare brands having an 
effective digital strategy. In 2021, we launched 
a new Digital Excellence training programme 
for our commercial teams, and we plan to 
expand with more content in 2022.

 › As part of our wider Sustainability initiatives, 

we recently kicked off a series of workstreams 
to help us reduce the carbon footprint of our 
packaging and will be looking to factor this 
thinking into all future innovation projects 
as well as apply best practice to our current 
packaging estate.

 › We continue to strengthen our marketing 

investment in order to grow awareness of our 
key brands and build engagement to secure 
life-time value.

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Our Business Model

Working together to leverage 
our platform and maximise 
the value of our brands.

The platform we’ve created across EMEA, 
APAC and AMER enables us to both drive 
the growth of our existing brands and to 
acquire and integrate new assets with ease. 
This is how we create value and execute our 
growth strategy.

The key capabilities, expertise and 
relationships that enable us to drive  
value creation are centred around  
our commercial activities and the  
brand-specific support functions  
which underpin these.

c. 35%

of our consumer healthcare 
revenues are now derived  
from e-commerce

Global  
Marketing
 ›

Ensures consistency of promotion for 
each of our lead brands – global 
strategy with local implementation

 ›

Through our marketing excellence 
programme all our marketeers are 
trained to deliver insight-led campaigns, 
with tailored messaging to key 
customer groups

Commercial activities

Distributor  
network
 › Relationships with an extensive network 

of distributors around the world

 › Sales specialists located in key territories 
with responsibility for managing key 
accounts and partnering with distributors 
on e-commerce initiatives

E-commerce 
capability
 › Dedicated in-house resource with 

external domain expertise supporting 
interface with key online retailers – 
Tmall/Alibaba, JD.com, Amazon

 › Supported by brand protection activities

Innovation &  
development capability
 › Dedicated in-house resource and newly 
created team supporting key brands in 
the development of new line extensions

Regulatory expertise
 › Global capability with deep domain expertise across 

Medical/claims expertise
 › Key to supporting our focus on clinically valuable 

Brand-specific support activities

products & essential to supporting our licensed medicines

all categories of licensed medicinal products. A 
proven ability to register products in new territories 
and handle registration transfers and other complex 
regulatory projects

Supply chain management
 › Global sourcing and supply chain capability built up over 
20+ years with a mix of local and centralised resource

 › Data generation to support core claims in key markets 
and for the development of new claims and horizon 
scanning of the evolving regulatory landscape

 ›

Excellent relationships with c.60 CMOs; effective 
performance management and ongoing programmes to 
drive efficiency through cost of goods reduction 

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Our Strategy

Our strategy enables us to deliver 
sustainable business growth through 
maximising the value of our core  
Consumer Healthcare business, thereby 
increasing the number of people who can 
potentially benefit from our products. 

This is what enables us to progress towards our vision of becoming a leading international healthcare 
business, and being both the partner and employer of choice.

There are two core elements to our strategy: delivering organic growth from our key brands, and 
engaging in selective, complementary acquisitions that can leverage our established infrastructure to 
enhance this growth. Underpinning these are our investment in people and sustainable business strategy. 
Over the following pages we provide more detail around our core strategy, our progress in 2021 and our 
priorities for 2022. Similar commentary in relation to investing in people can be found on page 22, with 
our sustainability strategy being covered on pages 25 to 33.

Core strategy

Strategic 
elements:

Organic growth – 
key brands

Complementary  
acquisitions

See page 18

See page 19

 ›

Investing in marketing excellence and 
Innovation and Development (I&D) 
to drive growth in major Consumer 
Healthcare brands

 › Stable, cash-generative Prescription 

Medicines business provides 
synergy through in-house regulatory 
knowledge and supports growth

Focus on Consumer Healthcare
 ›
 ›
Leveraging global platform
 › Strong balance sheet means we 
are increasingly well placed to 
participate in complementary 
acquisitions

Underpinned by

Strategic 
elements:

Investing  
in people 

Sustainability 

See page 22

See page 25

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Our Strategy continued

Organic growth 
– key brands

The primary driver of organic 
growth is our Consumer 
Healthcare portfolio.

Our key brands, Kelo-cote, Amberen and 
Nizoral, are all well-established in their 
respective core markets, with strong claim sets 
and good clinical utility – enabling them to 
deliver real value to users. All target growing 
demographics, making them well-suited to 
digital marketing and e-commerce, and all 
offer good innovation opportunities too. It is this 
combination of brand characteristics, coupled 
with the operating platform we have built across 
EMEA, APAC and AMER, and the expertise and 
relationships underpinning this, which provides 
the opportunity for us to drive double digit 
growth from these brands.

Many of our smaller consumer brands share 
similar characteristics, enabling them to benefit 
both from the platform and from a common 
approach to driving growth, focused on marketing 
excellence and where appropriate, innovation.

See-through revenues*

2021

2020

£44.5m

  Consumer Healthcare

  Prescription Medicines

£47.8m

£93.0m

£121.8m

Progress in 2021:
 › Delivered a 430 basis point improvement 
in gross margin, including the first full year 
of Amberen – allowing for increased 
investment in marketing and Innovation & 
Development (‘I&D’) to accelerate future 
organic growth

Innovation & development (I&D)
I&D at Alliance encompasses a broad range 
of activities aimed at creating value through:

 › New product development – brand 

extensions (new formulations, targeting 
related sub-sectors), or new presentations

 › New thinking – for example, classification 
switches, or the creation of new claims for 
a product

 › New therapeutic indications

 › Refreshing existing products to maintain 

 ›

consumer appeal

Implemented a new cross-border 
e-commerce distribution agreement for 
Kelo-cote, enabling us to move closer to 
the customer and giving further control of 
our distribution chain

 › Rolled out a new I&D process, supported 
by a dedicated team, to develop and 
deliver an innovation pipeline for our key 
consumer brands. This will enable us to 
maintain the relevance of our brands to 
consumers by extending the reach of a 
number of our larger consumer brands, 
through brand extensions

Priorities for 2022:
 › Continuing our focus on I&D, with the first new 
products arising from this process expected to 
launch in 2022

 ›

Extending our cross-border e-commerce 
platform in China, to include additional  
brands, through the creation of an Alliance 
multi-brand store

 › Realising the growth potential from Amberen 

through increasing our focus on brand 
positioning, executing a new integrated 
marketing campaign and starting to build  
an innovation pipeline for the brand to 
underpin its longer-term growth

* 

 Non-IFRS alternative performance measures (see note 34).  
See-through revenue includes all sales from Nizoral as if they had been invoiced by Alliance as principal. For statutory accounting 
purposes the product margin relating to Nizoral sales made on an agency basis is included within Revenue, in line with IFRS 15.

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Our Strategy continued

Enhancing our growth 
through complementary 
acquisitions

We are a selective acquiror, 
seeking assets we can 
integrate into our platform 
and apply our skills and 
know-how, to generate 
strong returns.

Our strategy is to acquire 
new products which meet our 
selective acquisition criteria 
and integrate these into the 
business efficiently, to enhance 
our growth.

The platform we have created across EMEA, 
APAC and, more recently, the US, enables us to 
acquire and integrate new assets with ease – we 
continue to evaluate opportunities which meet our 
selective acquisition criteria to further develop our 
business. We typically review around 80 to 100 
opportunities a year.

Our well-established relationships within the 
consumer healthcare M&A market, clear 
acquisition criteria and track record mean 
we continue to have good access to new 
opportunities, whilst our continued strong cash 
generation means we can deleverage quickly, 
replenishing our available debt capacity.

Progress in 2021:
 › Amberen integration completed, helping to 
both increase our presence and develop  
our operating platform in the US

 › Around 80 acquisition opportunities  

reviewed, of which three progressed to  
full evaluation

 › Net debt reduced by £22.4m, with leverage 
falling from 2.43x following the acquisition  
of Amberen in December 2020, to 1.73x at  
31 December 2021

Priorities for 2022:
 › Continuing to identify, evaluate and progress 
new opportunities which will deliver value 
to shareholders and help us to achieve our 
growth ambitions

 › Continuing to maintain the strength of our 

pipeline and our funding capabilities in both 
debt and equity

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Our Strategy continued
Case study

Responding to 
the acceleration  
in e-commerce 
growth

In 2021, we continued to take advantage of the 
change in consumer behaviour by embracing 
e-commerce opportunities both locally and 
cross-border (‘CBEC’), with a particular focus on 
Kelo-cote in China. In August 2021, we entered 
into a new CBEC distribution agreement for Kelo-
cote, bringing us closer to the customer and giving 
us increased control of our distribution chain. 
Working with our partner, we launched Kelo-cote 
flagship stores on the China CBEC marketplaces, 
Tmall and JD.com, to further accelerate top-line 
growth in this key market. The initial response has 
been very encouraging.

In 2021, around 25% of Group sales were 
e-commerce related, representing around one 
third of our total Consumer Healthcare sales. In 
addition to CBEC sales, which remain a key focus, 
this also included sales in the UK and US through 
platforms like Amazon, Walgreens.com and Boots.
com. In 2022, in addition to optimising our existing 
e-commerce sales channels, we plan to make a 
number of our other brands available to Chinese 
consumers through e-commerce platforms, and 
also to expand our geographical presence on 
marketplace platforms in South-East Asia, a region 
with high e-commerce growth.

Global retail e-commerce 
revenues reached $4.9 trillion  
in 2021, with COVID-19  
driving growth of 16.3%.  
Retail e-commerce sales now 
represent 19.0% of total retail 
sales, up from 17.9% in 2020*. 

E-commerce growth 
The personal care category, which 
includes healthcare products, grew 
18.4% in 2021 to reach $260 
billion. This presents a significant 
opportunity for us to drive enhanced 
revenue growth*.

* 

 Source: e-commerce report 2021 – Food and Personal Care – Statista Digital Market Outlook, June 2021.

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Our Strategy continued
Case study

Developing  
our platform 
in the US

2021 saw significant transformation 
of our business in the US, following 
the acquisition of Amberen at the 
end of 2020. We now have a solid 
platform from which to support 
growth in the region and to scale up 
further when suitable acquisition 
opportunities arise.

The development of our business in the US, the 
largest and one of the fastest growing consumer 
healthcare markets in the world, has been a key 
strategic focus for us in recent years. Initiated with 
the acquisition of Vamousse in 2017, it was the 
Amberen acquisition in late 2020 which brought 
pivotal growth.

Throughout 2021, in parallel with the integration 
of Amberen, we have been strengthening 
our operating capabilities: redesigning our 

organisation structure, bringing in new people, 
and upskilling existing colleagues, to create a 
team who can both commercialise new products 
and manage growth. We’ve also migrated our 
US headquarters to new, larger premises, to 
accommodate our growing team.

Our aim in 2022 and beyond is to further exploit 
the platform we have established in the US through 
the inclusion of additional OTC products. 

New products 
We expect to launch a number of 
new products/line extensions in the 
US over the next 12–18 months, 
and continue to actively look for US 
acquisition opportunities to build on 
our strengths in this market.

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Our Strategy continued

Investing  
in people

People are a key element of  
the Alliance mix. Our vision is 
to be the employer of choice.

To achieve this, it’s crucial that we continue to 
invest in our employees and to recognise the 
changes and challenges to working patterns that 
have come about in response to the pandemic and 
respond accordingly. Our overriding objective 
is to continue to ensure that our resourcing 
adequately supports the business’ medium-
term growth ambitions – and that our strong 
collaborative and inclusive culture, and the  
people who form part of it, continue to thrive.

Additional metrics on employees can be found 
in Sustainability – people and human capital 
management on page 30

*  As at 31 December 2021.

1 

 Defined as those running major divisions or departments, but not part of 
the executive team.

Employees by gender*:

Board & SLT (n=10)

2021

2020

  Male 

  Female 

80% 

20%

(2020: 80%)

(2020: 20%)

Senior managers1 (n=27)

2021

2020

  Male 

  Female 

74% 

26%

(2020: 78%)

(2020: 22%)

All employees (n=245)

2021

2020

  Male 

  Female 

42% 

58%

(2020: 43%)

(2020: 57%)

Total headcount (incl. non-execs and 
fixed term contractors (FTCs))

256

(2020: 246)

Employee engagement (GPTW survey):

Survey response rate:

74%

(2020: 73%)

Overall Trust 
Index© rating:

76%

(2020: 79%)

Progress in 2021:
 › We continued to strengthen our employee 

Priorities for 2022:
 › Action findings from the 2021 GPTW survey: 

engagement, through actioning findings from 
the 2020 Great Place To Work ® (GPTW) 
survey and ensuring that the employee base 
stayed connected, particularly through 
extended periods of remote working

 › We developed and implemented new, more 
flexible working arrangements based on 
insights gained from the Ways of Working 
survey, which we continued to run on a regular 
basis throughout 2021 to check in on how 
employees were feeling, identify any issues or 
requirements for additional support, and inform 
our future plans

 › We ensured the effective integration of new 
employees joining our US business following 
the Amberen acquisition

 › We put in place a global employee assistance 

programme as an additional benefit 
for employees

 › We continued to develop and refine our 

recruitment and orientation processes, and 
succession planning

five priority areas have been identified 
and local focus groups will be used to gain 
additional insight

 › Continue to test and refine our new ways of 

working to ensure this works successfully both 
at a business and individual level

 › Continue to bring new people into the business 
to ensure our resource capability continues 
to support our growth ambitions for 2022 
and beyond

 ›

Progress with the implementation of our new 
HR system (scoping and planning already 
underway in 2021)

Great Place to Work 
We were delighted to achieve Great Place To Work ® 
(GPTW) certifications in the UK and in China again this 
year – and also to be Great Place to Work-certified for  
the first time in Singapore 

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Key Performance Indicators

We set out here  
our key financial 
performance measures.
These are the primary 
measures used by 
management to monitor 
business performance, 
both against short-term 
budgets and forecasts 
and longer-term 
strategic plans.

Financial KPIs:

See-through Revenue*

£169.6m +23%

(2020: £137.5m)

Underlying EBITDA*

£48.6m +26%

(2020: £38.6m)

Underlying EBIT/Operating profit *

£45.6m +24%

(2020: £36.8m)

2021

2020

2019

2018

£169.6m

£137.5m

£144.3m

£124.0m

2021

2020

2019

2018

£48.6m

£38.6m

£39.4

£32.4m

2021

2020

2019

2018

£45.6m

£36.8m

£37.4m

£28.9m

Underlying Profit Before Tax

£42.2m +26%

(2020: £33.5m)

Underlying Basic EPS

6.39p +25%

(2020: 5.11p)

Dividend Per Share

1.691p +5%

(2020: 1.610p)

2021

2020

2019

2018

£42.2m

£33.5m

£32.9m

£28.1m

2021

2020

2019

2018

6.39p

5.11p

5.09p

4.54p

2021

2020

2019

2018

0.536p

1.691p

1.610p

1.464p

Free Cash Flow*

£30.2m -12%

(2020: £34.1m)

Leverage1

1.73x 

(2020: 2.43x)

Net Debt*

£87.0m -20%

(2020: £109.4m)

2021

2020

2019

2018

£30.2m

£34.1m

£29.1m

£16.1m

2021

2020

2019

2018

1.73x

1.48x

2.43x

2.33x

2021

2020

2019

2018

£87.0m

£109.4m

£59.2m

£85.8m

* 

1 

 These measures constitute Alternative Performance Measures (‘APMs’), as defined in note 34 to the Financial Statements.

 Leverage is defined as: Adjusted net debt/enlarged Group EBITDA, calculated using pro forma EBITDA on a trailing 12-month basis for acquired entities, in line with our banking covenants.

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Additional Information

Key Performance Indicators continued

In addition to the 
financial KPIs detailed 
overleaf, we employ 
a number of other 
internal performance 
measures to enable the 
effective management 
of our business.

Other internal performance measures:
Portfolio evolution (driver for organic revenue growth and margin improvement):

Revenue*: Consumer Healthcare

£121.8m +31%

(2020: £93.0m)

Total headcount* 

256 +0

(2020: 246)

2021

2020

2019

2018

£121.8m

£93.0m

£92.4m

£70.3m

2021

2020

2019

2018

256

246

214

218

* 

 Defined as total number of employees on payroll as at 31 December.

Employee engagement: 
GPTW Trust Index© rating: 76% (2020: 79%)

Working capital management:
Supplier payment days1: 46 (2020: 52)

1 

 Calculated as the month-end value of trade creditors relative to the 
trailing 12 months cost of goods, expressed as a days equivalent, 
averaged over the year.

Sustainability: 
Further detail on our key sustainability metrics 
can be found on pages 22 to 33.

Revenue*: Consumer Healthcare as a % of total

72% +4%

(2020: 68%)

2021

2020

2019

2018

72%

68%

64%

57%

GM%*: Total

64.5% +430bp**

(2020: 60.2%)

2021

2020

2019

2018

* 

 See-through basis. 

** 

 Basis points.

64.5%

60.2%

59.7%

58.6%

Other measures
We also employ a broad range of other 
measures to help us manage business 
performance, including but not limited to: 

 › Brand revenues, margins and contribution, 
by management region and having regard 
to brand prioritisation for marketing 
investment and innovation 

 › Measures around the level and nature 

of acquisition opportunities

 ›

Post-acquisition performance 
evaluation measures

 › On-time in-full delivery, out-of-stocks  
(to ensure continuity of product supply)

 ›

Inventory levels, provisioning and ageing 
profile; trade receivables and payables 
levels and ageing profiles (working 
capital management)

We do not disclose the related metrics 
associated with these measures, on the basis 
that they are commercially sensitive and/or 
intended for internal use only.

24

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Sustainability Overview

Sustainability
Working together  
to deliver sustainable 
business growth.

Our approach
During 2021, we refined and formalised 
our approach to sustainability, under the 
direction of the newly established ESG 
Committee, creating our sustainability 
framework, developing actionable plans for 
each material area, and increasing our focus 
on environmental considerations, including 
climate change, metrics, and reporting.

Our sustainability framework
Our sustainability framework identifies the 
eight areas material to our business that we 
need to concentrate our efforts on to assure 
the long-term future of the business and to 
deliver on our Purpose – to improve the lives 
of consumers and patients through making 
available a range of clinically valuable 
healthcare products. We refer to these as our 
‘Areas of Focus’.

Supply chain 
management

People &  
human capital 
management

Product 
quality & 
safety

Delivering 
sustainable 
business 
growth

Ethical sales 
practices

Business 
ethics

Environmental 
impacts – supply 
chain & logistics

Packaging 
lifecycle 
management

Product 
environmental 
H&S

Our contribution to the United 
Nations Sustainable Development 
Goals (UNSDGs)
The UNSDGs to which our business activities 
contribute are set out below. We believe 
we can contribute most value to Sustainable 
Development Goal 3 (Good Health & 
Wellbeing: Ensure healthy lives and promote 
well-being for all at all ages), as this aligns 
directly with our Purpose – to improve the 
lives of consumers and patients through 
making available a range of clinically 
valuable healthcare products.

Further detail around how Alliance contributes 
to the UNSDGs can be found on our website 
alliancepharmaceuticals.com

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Sustainability Overview continued

We recognise that single use plastics and 
packaging recyclability are an increasing 
concern for consumers. In 2022 we will be 
undertaking an extensive review of all our 
packaging componentry, across our portfolio 
and supply chain, to inform the development 
and focus of our sustainable packaging 
strategy with a view to establishing and 
communicating clear targets in this area.

Unlike some consumer goods categories, 
where packaging changes can be implemented 
relatively quickly with limited hurdles, in the 
healthcare market, particularly with regards 
pharmaceutical products, any change in 
packaging materials cannot be made without 
a variation to the product license, which in 
the case of changes to primary packaging, 
requires the generation, submission and 
approval of supporting stability data.

With this in mind, in 2021, we created a 
Sustainable Packaging programme team, 
to work towards the reduction of single-use 
plastics and increasing the use of Post-
Consumer Recycled (PCR) materials across 
our portfolio. Going forwards, all new product 
developments will require full consideration 
and review of packaging components to 
ensure the final presentation is aligned with the 
sustainability targets we set.

 › Worked with external consultants to quantify 
our Scope 1, 2 & 3 carbon emissions, as a 
precursor to the development of our carbon 
action plan and the setting of targets for 
carbon emissions reduction for both our direct 
(Scope 1 & 2) and indirect (Scope 3) emissions

 › Kicked off a sustainable packaging programme 
in Q4 2021 to develop and implement a ‘fit 
for purpose’ strategy for packaging lifecycle 
management across our portfolio

 ›

 ›

Established a Sustainability Forum in Q4 2021, 
comprising a group of employees who will work 
with the corporate sustainability lead to identify 
and deliver small-scale sustainable change 
initiatives across the business. This has initially 
been focused on our UK operations, with wider 
regional participation planned for 2022

Evolved our corporate website to include a 
dedicated section on sustainability (‘Acting 
Responsibly), to act as a repository for our 
sustainability content going forwards 

Our priorities for 2022:
We have made good progress with our 
sustainability initiatives in 2021, however we 
recognise that this is a journey and there is still 
much to do – particularly as the reporting and 
assurance requirements around ESG, and related 
sustainability considerations, continue to evolve.

Overview of progress in 2021:
Over the course of the year, we have:

 ›

Formalised our approach to sustainability 
and strengthened our governance processes 
through the creation of a Board-level ESG 
Committee in February 2021. The committee 
works with the Senior Leadership Team (SLT) 
and the corporate sustainability lead in the 
development and implementation of our 
sustainability strategy

 › Developed our sustainability framework; 
identifying then reporting against the key 
metrics underpinning this. We also mapped 
our sustainability disclosures and accounting 
metrics to the relevant elements of the 
Sustainability Accounting Standards Board 
(SASB) standards for the first time, and will look 
to publish the results on our website in 2022

 ›

Published our Business Principles, together 
with our Anti-Bribery and Corruption 
Policy, Whistleblowing Policy, Anti-Modern 
Slavery Policy and Diversity, Equality, and 
Inclusion Policy

 › Concluded the implementation of our Know 
Your Supplier (‘KYS’) programme, with 
the improvements in supplier management 
now embedded as part of our business-as-
usual processes

 ›

Engaged with our institutional investors, 
to better understand their requirements as 
regards ESG factors and sustainability, and 
the metrics and disclosures in which they are 
most interested to help shape our sustainability 
framework and strategy development

26

Sustainable packaging 
Awareness of environmental 
issues is becoming more 
widespread, with consumers 
and retailers increasingly 
choosing products that support 
a lower carbon footprint.

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

Sustainability Overview continued

In 2022, our focus will be on:

› Continuing to develop our environmental
strategy and our response to climate
change. We have committed to achieve
carbon neutrality for our 2021 Scope 1 &
2 emissions in the UK in 2022 through the
use of sequestration schemes. We will also
be increasing our levels of engagement
with our CMOs and logistics partners to
better understand their carbon footprints
and emissions reduction strategies and
the implications these have on our end-to-
end carbon footprint; actively looking for
opportunities to reduce the Scope 3 carbon
emissions in our supply chain as part of our
overall carbon reduction plan

› Developing and implementing a sustainable

packaging strategy, together with appropriate
targets and delivery plan

› Continuing to evolve our data collation and
reporting capabilities – particularly around
the composition of our product packaging
and to support the quantification of our
Scope 3 emissions

› Developing suitable performance metrics

and targets for those areas of our Framework
where none exist currently, which we can use
as a basis for measuring our progress in future
years. This will include carbon reductions
targets (aligned with the Science Based Targets
Initiative (‘SBTi’)) and targets around the
sustainability of our product packaging.

We intend to publish emissions reductions 
targets in late 2022 for Scopes 1 & 2 and 
are aiming to set Scope 3 targets in 2023

›

Progressing towards full disclosures in line with
the Task Force on Climate-related Financial
Disclosures (TCFD) recommendations for 2022

› Continuing to improve the assurance

framework around our ethical business
practices, to ensure that both our suppliers
and distributors continue to operate their
businesses ethically and in line with all
relevant regulatory requirements

› Continuing to develop the sustainable business
content held on our website, the transparency
of our disclosures around how we operate as
a business, and where we’re focusing our
efforts to ensure we remain sustainable over
the longer term

›

Progressing ideas generated through the
Sustainability Forum and other small-scale
initiatives, both in the UK and across our
regional offices

Our approach to each of the Areas of Focus 
identified in our Sustainability Framework, 
together with key metrics, our progress and 
achievements in 2021, and our priorities and 
focus for the coming year, are set out on  
pages 28 to 31.

What has become increasingly evident to us, 
particularly in the context of our response to wider 
societal challenges such as climate change, is the 
importance of working collaboratively – both within 
our own business and with our suppliers, logistics 
partners, distributors, and other stakeholders, if we 
are to make meaningful progress. This is particularly 
true for carbon emissions, given that a significant 
majority of our Scope 3 emissions originate within 
our supply chain and logistics activities, where our 
ability to directly control emissions is limited.

More information can be found on our website 
https://www.alliancepharmaceuticals.com/
acting-responsibly/environment

Environmental considerations 
Working together with our suppliers, logistics 
partners, distributors and other stakeholders 
will be key to the delivery of our environmental 
strategy, as we all seek to address common 
challenges around climate change.

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Sustainability Performance

Product quality & safety

Ethical sales practices

Business ethics

What it covers

Ensuring we have robust quality assurance systems in 
place to ensure the quality and safety of our products 
and to mitigate the supply of counterfeit product

Ensuring the claims made by our products can be properly substantiated and 
that we maintain ethical business practices in the marketing, advertising, and 
selling of our products

Why it’s important

Maintaining consumers’ and patients’ trust in the 
quality and safety of our products is essential to the 
maintenance of our corporate reputation and our ability 
to successfully market our products

Ensuring the accuracy and appropriateness of promotional materials and the  
claims made by our products is key to maintaining consumers’ and patients’ trust  
in our brands

2021 Overview

9

22

Supplier audits carried out

(2020: 5)

Representing 67% coverage of our supplier base on a 
rolling 3-year average basis1

Number of external regulatory inspections Alliance 
operating companies have been subject to: 7 (2020: 5)

No enforcement actions were taken by Competent 
Authorities in response to non-compliance with 
appropriate manufacturing and regulated standards 
in 2021 (2020: 0)

Routine internal audit assessments carried out
(2020: 40)

Internal audit assessments are carried out on a periodic basis to ensure the 
robustness of our promotional review procedures. Coverage is targeted at 
a constant 10% of total promotional pieces approved per annum. Actual 
coverage in 2021 was 4.5%, down from 9.4% in 2020 

No upheld complaints were made to the ABPI, PAGB, FTC, NAD, or other 
Codes of Practice bodies regarding promotion of Alliance products, where 
Alliance is directly responsible for promotion in 2021 (2020: 0)

Modern slavery, bribery and corruption, ethical 
considerations around our interactions with healthcare 
professionals and the pursuance of other ethical 
business practices

We are committed to operating our business in 
an ethical and responsible way, ensuring that we 
have appropriate policies in place, that employees 
are properly trained on them and that appropriate 
escalation routes exist for non-compliance

1,407 

Online2 course completions
(2020: 1,359)

We now have approved escalation procedures in place 
to work with any supplier who does not meet our ethical 
standards, with defined timelines for remediation and 
provision for eventual termination of the relationship, 
where issues are not satisfactorily resolved

In 2021, the total amount of monetary losses we 
incurred as a result of legal proceedings associated 
with bribery, corruption and other unethical business 
practices was £Nil (2020: £Nil)

Focus for 2022

Continuing to assure the quality and safety of our 
products through our rolling, risk-based programme of 
supplier quality audits

Continuing to ensure that the systems and processes we have in place to ensure 
the accuracy and appropriateness of promotional materials remain fit for 
purpose and that our internal control systems continue to operative effectively  
in order to minimise the risk of non-compliance

Obtaining written confirmations from our contract 
manufacturers and suppliers that they comply with our 
ethical standards (phased approach – target completion 
end 2023)

1 

2 

 Calculated as the total number of suppliers audited over the 3 years from 2019 – 2021, divided by the number 
of active suppliers as at 31 December 2021.
 Vinciworks is a suite of online training modules covering anti-bribery, anti-money laundering, competition law, 
GDPR, market abuse, Modern Slavery Act, sanctions and the prevention of tax evasion.

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Sustainability Performance continued

Product environmental H&S

Packaging lifecycle management

What it covers

Ensuring our products are made with environmentally 
friendly ingredients; identifying and eliminating 
REACH1 substances of very high concern (SVHC) from 
our products – and ensuring we have a robust process 
in place to identify and manage emerging materials 
and chemicals of concern

Reducing the environmental impact of our product packaging, 
through reducing packaging volume/weight, increasing the use of 
recycled materials, and ensuring that as much of our packaging as 
possible is made from materials that can be recycled, reused  
and/or composted

Why it’s important

We are committed to operating our business in a way 
which minimises the impact on the natural environment 
– this means ensuring that our products are made 
with environmentally friendly ingredients and do not 
contain materials and chemicals of concern

We are committed to operating our business in a way which 
minimises the impact on the natural environment – reducing the 
environmental impacts of our product packaging is one way of 
achieving this. Reducing packaging volume/weight will also reduce 
the environmental impact of transporting products to consumers

2021 Overview

We have established environmental scanning 
processes to identify and manage emerging materials 
and chemicals of concern as soon as we become 
aware of these – reformulating products where 
necessary, in order to ensure that we are able to stay 
compliant with new regulations as they emerge

In Q4 2021, we set up our Sustainable Packaging programme, to 
develop and implement a ‘fit for purpose’ strategy for packaging 
lifecycle management. This will enable us to address usage and 
waste across our packaging estate at a holistic level, reducing or 
removing unnecessary elements of our packaging, changing its 
composition, replacing less sustainable materials, e.g., single-use 
plastics, with more sustainable alternatives, increasing the use 
of recycled content and/or making packaging easier to recycle, 
or biodegradable

Focus for 2022

Continuing to ensure that our processes for identifying 
and managing emerging materials of concern remain 
fit for purpose and that any REACH1 SVHC’s are 
eliminated from our products on a timely basis

Progress the creation and implementation of a sustainable 
packaging strategy; including the creation of a roadmap for the 
associated workstreams which feed into this and the setting of 
targets/defining our level of ambition

Packaging sustainability will now be factored into all Innovation 
& Development projects at the design stage, and we will be 
looking to embed this thinking into brand strategies more widely 
going forwards 

1 

REACH – Registration, Evaluation, Authorisation and Restriction of Chemicals

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Sustainability Performance continued

People and human capital management

What it covers

This covers a wide range of social factors, including diversity and inclusion, culture 
and employee engagement, working conditions, reward structures, training and 
development, and opportunities for progression

Why it’s important

Investing in People is one of the core elements of Alliance’s strategy – as such, the 
recruitment and retention of high-quality and highly motivated employees is what lies 
at the heart of our business success

2021 Overview

Age profile of employees 

Length of service of employees

Employees by location

Employee turnover rate1:

2021

2020

2021

2020

2021

2020

Voluntary

20.6% 

(2020: 9.6%)

Involuntary

8.6% 

(2020: 0.4%)

  Under 29 
2021 30 
2020 26

  30–39 

2021 75 
2020 68

  40–49 

2021 72 
2020 74

  50–59 

2021 55 
2020 54

  60+ 

2021 11  
2020 10 

  Not known 
2021 2  
2020 13 

  Under a year 

2021 61 
2020 50

  1–2 years 
2021 38 
2020 31

  2–5 years 
2021 78 
2020 91

  5–10 years 
2021 46 
2020 41

  10–15 years 

2021 15 
2020 24

  15+ years 
2021 7 
2020 8

  UK & ROI 
2021 170 
2020 168

  APAC 

2021 28 
2020 31

  Central Europe 

  US 

2021 28 
2020 36

2021 16 
2020 13

Additional information on how we invest in  
our people is provided on page 22 and on  
our website

Focus for 2022

Analysing and actioning key findings from the Great Place To Work® (GPTW) survey, 
with focus groups planned for H1 2022

Continuing to invest in our capability development and the recruitment and onboarding 
processes which support this, including the roll-out of a new graduate training scheme

Continuing to refine our ways of working to ensure our new hybrid model is working 
effectively across all areas of our business

1 

 Voluntary turnover is defined as those leaving the business by virtue of resignation, or retirement, or the expiry of fixed 
term contracts; involuntary turnover is defined as those leaving the business by virtue of dismissal or redundancy.

30

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Sustainability Performance continued

Supply chain management

Environmental impacts – supply chain & logistics

What it covers

Ensuring that we have good visibility of our supply chain so that we can ensure that our 
suppliers adhere to the same ethical standards as we do, and that they are committed  
to sustainable manufacturing practices, which aim to safeguard people and planet

Greenhouse gas (GHG) emissions and other environmental impacts associated with our supply chain and 
logistics (warehousing and distribution) activities, including transportation of products by our distributors

Why it’s important

Our commitment to operating our business in a sustainable way goes beyond the 
activities we carry out ourselves. Our contract manufacturers are an integral part of 
our business activities – and as such we expect them to adhere to the same ethical 
standards which we have set ourselves, and to support our commitment to operate our 
business in a sustainable way

As a responsible business, we have a duty to do what we can to reduce the environmental impacts of our 
business activities

2021 Overview

Know Your Supplier (KYS) programme implemented, providing increased visibility 
of potential ‘red flags’ in our supply chain. Associated compliance and escalation 
processes strengthened to facilitate timely resolution of issues

The quantification of our Scope 3 carbon emissions in 2021 revealed that more than 80% of our GHG 
emissions originate in our supply chain and logistics activities – including onward transportation of products  
by our distribution partners, so focusing on this area will be key to reducing our overall Scope 3 emissions

53 finished goods supply partners are now being monitored by this programme, 
representing 90% of our total finished goods suppliers 

No significant issues were detected in 2021

We have already taken a number of actions to reduce carbon emissions in our supply chain, including:

 ›

 ›

Truncating the supply chains for our lead brands (Kelo-cote, Amberen, Nizoral) to produce closer to 
market, reducing transportation emissions

Improving the efficiency of our logistics operations, through increased order sizes/reduced frequencies 
and the use of sea rather than air freight

More detail around the development of our environmental sustainability strategy can be found on page 33

Focus for 2022

Review findings from initial test phase of supplier self-assessment around modern 
slavery, labour practices and health & safety practices, to determine whether there is 
value in extending this more widely

In 2022, we plan to reach out to our larger CMOs and LSPs (covering two thirds of our 2021 spend) to better 
understand where they are on their respective emissions reduction journeys and to obtain their Scope 1 and 2 
data to help improve the methodology used for our Scope 3 calculations

Carry out assessment of strategic suppliers’ sustainable sourcing ratings, and whether these 
could be usefully employed as part of a more holistic approach to supplier management

We will use the findings from this work to help us determine realistic Scope 3 emissions reductions targets and our 
overall path to net zero

We will also be looking to increase our focus on Modern Slavery audits (which may 
also include physical inspections, depending on the evidential value of the same), with 
a view to having a formal structure and system in place by the end of 2023, whereby 
10% of our contract manufacturers are audited annually on a rolling basis, whether  
this is based on an external recognised standard or one developed internally

An additional head is being recruited to support this area, and also our sustainable packaging programme

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Additional Information

Sustainability Performance continued

In addition to the eight Areas of Focus which make up our Sustainability 
Framework, there are two other areas which, whilst not material to the long-
term sustainability of our business, are nonetheless important to us from a 
broader societal perspective. These are the environmental impacts of our 
own operations, which are discussed further on page 83, in the context of 
our overall environmental sustainability strategy development and our social 
impact activities.

Social impact

What it covers

Social impact activities undertaken to benefit local communities around the world, 
including those involved in conflict and/or in the developing world

Why it’s important

Alliance has always had a strong ‘social conscience’ and commitment to work with 
its employees to support those in need, through donations (of cash, time, products) 
and fundraising activities

2021 Overview

In 2021, our social impact activities within our local communities were limited by 
the ongoing impacts of the pandemic, with many of our offices being subject to 
local work from home guidance for a significant part of the year

However, this didn’t stop us from continuing our efforts further afield. Through 
our continued support of International Health Partners (IHP), we enabled 31,979 
treatments to be sent to 13 countries in 2021, helping to provide around 10,600 
people with the medicine they need. This included responding to an urgent call from 
their NGO partner in Venezuela, for antimalarial medicine, in response to which 
we supplied 498 treatments to help meet the need

Focus for 2022

In 2022, in addition to continuing our support for IHP, we plan to resume our social 
impact activities within our local communities

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Developing our environmental sustainability strategy

This year, for the first time, we have recognised 
climate change as an emerging risk within 
our Principal Risks and Uncertainties and are 
continuing to work with external consultants 
to progress towards full disclosures in line with 
the Task Force on Climate-related Financial 
Disclosures (TCFD) recommendations for 2022. 
For 2021, we have made partial TCFD disclosures, 
which can be found on pages 78 and 79.

Over 80% of our 
GHG emissions 
originate in our 
supply chain and 
logistics activities.

We are currently in the early stages of developing 
our broader environmental strategy including our 
response to climate change.

Given the nature of our business, and our use of 
third-party distributors, contract manufacturers 
(CMOs) and logistics service providers (LSPs), 
the majority of our greenhouse gas emissions are 
classified as Scope 3. In 2021, we quantified our 
Scope 3 greenhouse gas emissions for the first 
time (based on data for 2020). We are using the 
results of this exercise, together with equivalent 
calculations to be undertaken for 2021, to help 
inform the development of our carbon action plan, 
with a view to setting carbon reduction targets for 
Scopes 1, 2 & 3 and our path to net zero in the 
near future.

In addition to revealing the significance of the 
emissions linked to our supply chain and logistics 
activities, which now forms one of the eight Areas 
of Focus within our Sustainability Framework, this 
exercise also revealed where opportunities may 
exist to try and improve the basis of measurement, 
particularly for Scope 3 emissions. In 2022, we 
plan to reach out to our larger CMOs and LSPs 
to better understand where they are on their 
respective emissions reduction journeys and  
to obtain their Scope 1 and 2 data to 
help improve the methodology used for  
our Scope 3 calculations. 

Whilst the environmental impact of our own 
operations (Scope 1 & 2) is relatively low, and so 
not material to the longer-term sustainability of our 
business, reducing them is nonetheless important 
to us from a broader societal perspective. 

The investments we’ve made in our UK 
headquarters building in recent years have 
significantly improved its energy efficiency, 
with additional upgrading and refurbishment 
work having been undertaken in 2021, further 
improving the building’s environmental credentials. 
We continue to actively look for ways to reduce 
our Scope 1 & 2 emissions, which amounted to 
90tCO2e for our UK operations in 2021, and will 
achieve carbon neutrality for these retrospectively 
in 2022, through the use of sequestration schemes. 

Outside the UK, our office premises tend to be 
held on all-inclusive operating leases, giving us a 
more limited ability to control their environmental 
footprint. We will however be looking to increase 
our understanding of the situation on an office-
by-office basis, to see what can be done, as we 
progress through 2022. We are also looking at 
ways we can reduce emissions attributable to 
some of the smaller categories in Scope 3, such 
as non-stock purchases, business travel, and 
employee commuting.

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Stakeholder Engagement

Stakeholder engagement 
– overview

Our principal stakeholders 
and their primary 
requirements

Our shareholders
 › Strong financial performance

 › Share price appreciation

 › Dividend income

 ›

Long-term sustainability of the business

Working together we  
create sustainable value  
for all our stakeholders.

The Board recognises the importance of 
maintaining an engaged and motivated 
workforce, dependable supply chains, customer 
confidence in our products, close relationships 
with healthcare professionals, good returns for 
our shareholders and social impact in both our 
local and wider communities.

Information on how stakeholder considerations 
have been considered by the Board in their 
decision-making in accordance with s172 of 
the Companies Act 2006 is provided within the 
Governance section on page 53. Additional 
content regarding our stakeholder relationships 
and how we manage these can be found on 
our website. 

Healthcare professionals
 ›

Engagement, education, information,  
and resources

 ›

Therapy area expertise

Debt providers
 › Strong financial performance 

 › Ability to service & repay borrowings

Our employees
 › Competitive reward structures

 › Share options

 ›

 ›

Flexible working

Learning & development opportunities on  
a global basis

Consumers & patients
 › Safe and effective healthcare products

Suppliers & partners
 › Continued business growth opportunities

Communities
Local engagement
 ›

 › Charitable & product donations 

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Financial Review 

Another excellent 
performance driven by 
strong revenue 
growth 

Underlying EBITDA*

£48.6m +26%

“Strong growth by our higher 
margin Consumer Healthcare 
brands, a change in CBEC 
distribution arrangements for 
Kelo-cote and the acquisition 
of Amberen led to further 
improvement in margins”

(2020: £38.6m)

Free Cash Flow*

£30.2m -12%

(2020: £34.1m)

* 

 Non-IFRS alternative performance measures (see note 34).

Alliance Pharma plc – Annual Report and Accounts 2021

35

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Financial Review continued

Summary underlying income statement
Year ended 31 December

Revenue summary
Year ended 31 December

See-through revenue*

Statutory revenue

Gross profit

Operating costs (including IFRS 2 share options charge)

Underlying EBITDA*

Depreciation and underlying amortisation

Underlying operating profit (EBIT)

Finance costs

Underlying profit before taxation

Reported profit before taxation

Underlying basic earnings per share

Reported basic earnings per share

Proposed total dividend per share

2021
£m

169.6

163.2

109.5

60.9

48.6

2.9

45.6

3.4

42.2

18.2

6.39p

1.37p

2020
£m

137.5

129.8

82.8

44.2

38.6

1.8

36.8

3.3

33.5

13.0

5.11p

1.51p

1.691p

1.610p

Growth

+23%

+26%

+32%

+38%

+26%

+68%

+24%

+4%

+26%

+39%

+25%

-9%

+5%

* 

 The performance of the Group is assessed using Alternative Performance Measures (‘APMs’), which are measures that are not defined under IFRS, but are 
used by management to monitor ongoing business performance against both shorter-term budgets and forecasts and against the Group’s longer-term 
strategic plans. APMs are defined in note 34.

 Specifically, see-through revenue includes all sales from Nizoral™ as if they had been invoiced by Alliance as principal. For statutory accounting 
purposes the product margin on Nizoral sales made on an agency basis is included within Revenue, in line with IFRS 15.

 Underlying profitability metrics are presented as we believe this provides investors with useful information about the performance of the business. In 2021, 
underlying results exclude the amortisation and impairment of acquired intangible assets, the CMA provision and restructuring costs; in 2020, underlying 
results exclude the amortisation and impairment of intangible assets, and costs associated with the acquisition of Biogix Inc. Further detail can be found in 
note 5.

Kelo-cote

Amberen

Nizoral*

Other consumer brands

Consumer Healthcare*

Prescription Medicines

See-through revenue* 

LFL Consumer Healthcare see-through revenue*,  
excluding Amberen

LFL see-through revenue*, excluding Amberen

Statutory revenue – Consumer Healthcare

Statutory revenue – Group

LFL Consumer Healthcare statutory revenue,  
excluding Amberen

LFL Group statutory revenue, excluding Amberen

2021
£m

48.8

19.2

20.6

33.2

121.8

47.8

169.6

102.6

150.4

115.4

163.2

96.1

144.0

2020
£m

34.7

–

21.0

37.3

93.0

44.5

137.5

93.0

137.5

85.3

129.8

85.3

129.8

Growth

+41%

–

-2%

-11%

+31%

+8%

+23%

+10%

+9%

+35%

+26%

+13%

+11%

CER 
growth

+47%

–

+1%

-9%

+36%

+8%

+27%

+14%

+12%

+41%

+30%

+16%

+14%

Revenues and operating profits 
The Group delivered a strong financial performance in the year, with see-through revenue increasing 23% 
to £169.6m (2020: £137.5m) and 27% at constant exchange rates (CER). Like-for-like revenue excluding 
Amberen, which was acquired in December 2020, increased 9% (12% CER). Group revenue was adversely 
impacted in 2021 by exchange rate movements, principally the strengthening of Sterling against the US Dollar, 
which depressed see-through revenue by approximately £5.1m. Statutory revenue increased 26% to £163.2m 
(2020: £129.8m) and rose 30% CER.

The strong growth in our higher margin consumer health brands, coupled with changes to our distribution 
arrangements for Kelo-cote and the acquisition of Amberen, led to a 32% increase in gross profit to 
£109.5m (2020: £82.8m). Consequently, gross margin increased 430 basis points (bp) to 64.5% of see-
through revenue (2020: 60.2%). Gross margin relative to statutory revenue was 67.1% (2020: 63.8%).

36

Alliance Pharma plc – Annual Report and Accounts 2021 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Financial Review continued

Underlying profit before tax increased 26% to 
£42.2m (2020: £33.5m) driving 50 basis point (bp) 
margin improvement to 24.9% despite increased 
operating expenses through the inclusion of the 
Amberen cost base, coupled with a modest increase 
in depreciation and underlying amortisation costs. 
Reported profit before tax increased 39% to £18.2m 
(2020: £13.0m). 

We increased our investment in the business in 2021, 
improving our operating capabilities and boosting 
the level of marketing support provided to a number 
of our brands. With the resumption of discretionary 
spend, which we deferred or cancelled in 2020 in 
response to the global pandemic, in addition to the 
aforementioned inclusion of the Amberen cost base, 
operating costs (defined as underlying administration 
and marketing expenses, excluding depreciation and 
underlying amortisation charges) increased 37% 
versus the prior year to £58.6m (2020: £42.8m). 
As a result, operating costs as a percentage of sales 
increased 3.5% to 34.6% of see-through sales 
(2020: 31.1%). 

The IFRS 2 share options charge for the year was 
£2.3m, up £0.9m versus that for the prior year 
(2020: £1.4m) reflecting an increase in the share 
price in 2021.

Net of the increase in operating costs and the 
share options charge, underlying earnings 
before interest, taxes, depreciation and 
underlying amortisation (EBITDA) increased 
26% in the year to £48.6m (2020: £38.6m), 
whilst underlying operating profit (EBIT) 
increased by 24% to £45.6m (2020: £36.8m). 

Reported operating profit increased by £5.3m 
to £21.6m (2020: £16.3m), with non-underlying 
items of £24.1m (2020: £20.5m). Further detail  
on non-underlying items is provided below and  
in note 5.

Depreciation and amortisation
Depreciation charges for the year were £1.6m, 
down £0.2m on the prior year (2020: £1.8m). In 
addition, we incurred £1.3m of amortisation costs 
relating to our new ERP system, which went live in 
2021. Following a change in accounting policy, the 
costs relating to this system are now treated as an 
intangible asset (previously included within tangible 
assets). Further detail is provided in note 2.9.

Finance costs
Finance costs remained in line with the prior year 
at £3.4m (2020: £3.3m), with a £1.0m increase 
in borrowing costs, reflecting the higher level of 
borrowings following the Amberen acquisition, 
being largely offset by higher net gains on currency 
movements in the year.

The average interest charge on gross debt during 
the year (including non-utilisation fees) was 2.24% 
(2020: 2.55%).

Non-underlying items
Non-underlying items in the year principally 
comprise amortisation charges for Prescription 
Medicines and certain other brand assets, 
impairment charges identified as a result of the 
annual impairment review (see note 11), a provision 
of £7.9m in relation to the Competition and 

Markets Authority (CMA) decision (see note 20) 
and restructuring costs relating to the closure of our 
offices in Milan and Los Angeles. For the prior year, 
non-underlying items comprised amortisation and 
impairment charges, together with costs relating to 
the Amberen acquisition. Further detail on non-
underlying items is provided in note 5.

Reconciliation of underlying to reported 
profit before tax
Year ended 31 December

Underlying profit before taxation

42.2

33.5

2021
£m

2020
£m

Non-underlying items:

Amortisation of acquired 
intangibles

Impairment of intangible assets 
and goodwill

CMA provision

Restructuring costs

Other

Acquisitions costs –  
Biogix Inc. (Amberen)

Total

(7.2)

(7.2)

(6.2)

(12.1)

(7.9)

(2.4)

(0.4)

–

–

–

–

(1.3)

(24.1)

(20.5)

Reported profit before taxation

18.2

13.0

Taxation
The underlying tax charge for the year was £8.0m 
(2020: £6.4m), which equates to an effective tax 
rate of 19.0% (2020: 19.0%). The total tax charge for 
the Year was £10.8m (2020: £5.0m), equating to an 
effective tax rate on reported profits of 41.6% (2020: 
38.3%) and includes a £5.0m charge following 
the increase in the UK tax rate from 19% to 25% 
(this charge relates primarily to an increase in the 
deferred tax balances on intangible assets).

Earnings per share
Underlying basic earnings per share, the 
measure used by the Board in assessing earnings 
performance, was 6.39p, an increase of 25% on the 
prior year (2020: 5.11p), reflecting the increase in the 
Group’s underlying profit after tax offset by a modest 
increase in the number of shares in issue.

Reported basic earnings per share decreased by 9% 
to 1.37p (2020: 1.51p)) due to the greater impact 
that non-underlying items had on reported earnings 
in the year versus the prior year.

Dividend
The Board is pleased to announce that it is proposing 
a final dividend payment of 1.128p per share for 
2021, an increase of 5% on the final dividend 
payment for 2020, taking the total dividend 
payment for the year to 1.691p (2020: 1.610p). 
The Board will continue to assess the level of future 
cash distributions having regard to overall business 
performance and future outlook.

The final dividend for 2021, subject to approval  
at the Company’s AGM on 18 May 2022, will  
be paid on 7 July 2022, to shareholders on the 
register on 10 June 2022. 

37

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Financial Review continued

Balance sheet
Intangible assets increased by £0.8m in the year to 
£413.7m (31 December 2020: £412.9m).

Following the successful deployment of Microsoft 
Dynamics D365 into the business in mid-2021, we 
conducted a review of the associated capitalised 
project costs, and as a result have transferred 
these capitalised costs, amounting to £15.0m, from 
property, plant and equipment to intangible assets 
in-line with the deployment of the live system into 
the business. These additions have effectively been 
offset by underlying amortisation charges of £1.4m, 
non-underlying amortisation charges of £7.2m 
and non-underlying impairment charges of £6.2m; 
the remaining balance being due to exchange 
rate movements and a £0.2m true-up for working 
capital relating to the Amberen acquisition.

Working capital
Net working capital at 31 December 2021 was 
£22.0m, an increase of £2.7m on that at the 
start of the year (31 December 2020: £19.3m), 
primarily reflecting movements in payables and 
receivables balances.

Inventories, net of provisions, reduced £1.8m to 
£21.1m at 31 December 2021 (31 December 
2020: £22.9m). This reduction was caused by 
the partial unwinding in H1 2021 of the higher 
inventory levels built up during 2020 in order to 
mitigate against any disruption to our supply chain 
following the UK’s departure from the EU, and to 
ensure continuity of supply through the pandemic.

Receivables increased by £5.7m, reflecting both 
the increase in revenues, and the timing of sales 
and cash receipts in the second half of the year, 
versus the equivalent period in 2020.

Payables increased by £1.2m, reflecting the 
phasing of invoices and payments around the year 
end, with a £2.8m reduction in trade payables 
being more than offset by a £3.8m increase in 
accruals and deferred income.

Provisions
In the year, the Group created provisions totalling 
£9.5m as at 31 December 2021 (31 December 2020: 
£Nil), £7.9m of which relates to the CMA decision, the 
remainder, £1.6m, being a provision for restructuring 
costs. Further detail is provided in note 20.

Cash flow and net debt
Free cash flow (see note 34 for definition) for the 
year remained strong at £30.2m (2020: £34.1m), 
with second half cash flows being significantly 
stronger than first half (H1 2021: £6.5m; H2 
2021: £23.7m), reflecting both the reversal of the 
favourable movements in net working capital seen 
at the end of 2020 during the first half of the year, 
and the timing of sales in the second half. Cash 
generated from operations decreased by 3% to 
£44.9m (2020: £46.4m).

As a result, net debt reduced by £22.4m to £87.0m 
at 31 December 2021 (31 December 2020: 
£109.4m), with Group leverage reducing to 1.73 
times (31 December 2020: 2.43 times). 

We expect our cash generation to remain strong 
in 2022, and for leverage to reduce below 1.5 
times by the end of the year, in the absence of 
further acquisitions.

Treasury and capital management
The Group’s operations are financed by retained 
earnings and bank borrowings, with additional 
equity being raised on a periodic basis to part-fund 
larger acquisitions. Borrowings are denominated in 
Sterling, Euro and US Dollars.

Implementing our ERP system 
We are already starting to see the business benefits 
from our ERP system, which went live in the first half 
of 2021, representing the culmination of a significant 
period of investment and cross-functional team effort 
in scoping, design, development and implementation 
activities. Used by our operations and finance teams 
around the world, the system has enabled us to 
simplify, standardise and automate business processes 
across the Group. Due to the high level of preparation 
work undertaken pre-implementation, the changeover 
from old to new systems was virtually seamless.

Group risk management policy is to hedge up to 
75% of estimated future foreign currency EBITDA 
exposure, for up to the next 18 months at any point 
in time. The Group uses forward foreign exchange 
contracts to implement this policy, which are 
generally designated as cash flow hedges.

The Group benefits from a £165m Revolving Credit 
Facility (RCF) and a £50m Accordion Facility, 
expiring in July 2024. This facility provides flexibility 
for the Group to pursue its acquisition strategy 
over the next couple of years to complement future 
organic growth. £48m of this RCF, together with the 
whole of the accordion facility, remained unutilised 
as at 31 December 2021.

The cash generated from our trading operations is 
applied as follows:

 ›

 ›

 ›

 ›

in reinvesting in our current portfolio of brands, 
with investment being primarily targeted at our 
larger Consumer Healthcare brands

in acquiring new Consumer Healthcare brands, 
to complement our existing portfolio and 
leverage our operating platform

in paying down debt; and 

in paying dividends to our shareholders.

Andrew Franklin
Chief Financial Officer

30 March 2022

38

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties

During the year, the Board reviewed the principal 
risks and uncertainties facing the Group and 
continues to focus on those which could threaten 
the sustainability of our business model, our 
reputation, future performance expectations, or 
in extreme cases, the solvency or liquidity of our 
business. The links between our principal risks and 
uncertainties and our strategy are set out in the 
table on pages 40 to 45. 

Principal risks are assessed on a residual basis 
according to our current view of their potential 
severity (being the combination of impact and 
likelihood), and assuming that existing plans 
for mitigation are, and remain, effective. The 
current positioning of each of our principal risks, 
based on our assessment of their residual impact 
and likelihood, is shown in the graph to the right.

The identified risks are not intended to be an 
exhaustive list of all the risks the Group faces but 
are the principal risks and uncertainties which 
the Directors believe include all known material 
risks in relation to the Group and the markets and 
industry within which we operate.

The environment in which we operate is constantly 
evolving and can be affected by events that are 
outside of our control and which may impact on 
us both operationally and financially. New risks 
may emerge, the potential impact of known risks, 
including how quickly they escalate, and/or our 
assessment of these risks may need to change. For 
2021, we have recognised a new emerging risk in 
relation to climate change.

In addition to the matters set out in the coming 
pages, and as announced by the Group on 
3 February 2022, the UK’s Competition and 
Markets Authority (‘CMA’) announced its finding 
that four companies, including Alliance, had 
infringed competition law (the ‘Infringement 

Decision’) in relation to the sale of prescription 
prochlorperazine. The Directors fundamentally 
disagree with the CMA’s finding. 

The Group believes that it has a strong case 
and will be appealing the CMA’s decision, and 
the proposed fine of £7.9m, at the Competition 
Appeal Tribunal which is expected to be heard 
in late 2022/early 2023. The Group continues 
to engage with its expert external legal team to 
prepare a robust and effective appeal against 
these allegations.

Environmental and Climate Change
An emerging risk is a risk around which we 
do not believe we have sufficient clarity 
currently to be able to assess its likely 
impact – and the likelihood of this impact 
occurring. Such risks are unlikely to impact 
the business in the near term, but have the 
potential to significantly impact the business 
ability to achieve its strategic objectives in 
the medium-longer term.

We have taken the decision to recognise 
environmental and climate change as 
an emerging risk this year, pending the 
completion of the scenario analysis needed 
to support full compliance with the disclosure 
recommendations set out by the Task Force 
for Climate-related Financial Disclosures 
(TCFD), which we expect to complete during 
2022. This should provide the necessary 
insight into whether climate change is likely  
to constitute a material risk to our business.

Analysing identified risks

12

8

2

5

1

4

6

9

10

7

11

t

c
a
p
m

I

3

Strategic risks 

Operational risks 

Compliance risks 

Likelihood

1

   Organic growth:  
innovation & competition

2    Inorganic growth – acquisitions

3   Product safety

4   Supply disruption

5   Business systems

6   Cyber-security

7   People

9   Product regulations

10   Legal & compliance

Financial risks 

11   Foreign exchange

Other risks 

8   Supply chain management

12    Pandemic, geopolitical  
and worldwide risks 

39

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties continued

Links to strategy:

Organic growth  
– key brand potential

Trends:

Investing in people

Risk has increased versus last year

Risk has not changed materially since last year

Complementary acquisitions

Acting responsibly

Risk has reduced versus last year

Strategic risks

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

 ›

 ›

 ›

1.  Organic 
growth: 
innovation & 
competition

Risk that we are unable to achieve our strategic growth ambitions 
due to a failure to keep pace with changing consumer preferences 
or due to a failure to identify and exploit new geographic markets 
for our products.

The products we sell are subject to normal market forces, so 
demand may fall, or the price we can achieve may be reduced, 
as our products face new or increased competition in response to 
changing consumer preferences for products or sales channel.

As a significant portion of our international sales are made via 
distributors, we are also at risk from losing a distributor or failing to 
secure a suitable distributor in existing or new markets. Widening 
sales distribution channels to include digital online sales platforms 
means sales could be affected should third-party systems become 
temporarily unavailable. 

We also face the risk of some of our more popular consumer 
products being subject to counterfeiting, where others seek to take 
advantage of the reputation built up in our brands for their own 
commercial exploitation. Equally, there is also a risk that once a 
patent has expired, others in the market may copy our products 
and seek to increase competition.

2.  Inorganic 
growth – 
acquisitions

Risk that we are unable to achieve our strategic growth ambitions 
due to a lack of suitable acquisition opportunities, a failure 
to secure suitable assets, or to effectively integrate assets 
once acquired.

There can be no guarantee that the Group will be able to identify 
suitable targets to continue to boost its growth through acquisitions. 
The market for high-quality assets – whether brands or corporates 
– is highly competitive and the Group may find itself unable to 
compete if the pricing of targets proves prohibitive.

As the Group looks to increase the size of acquisitions, the 
complexity around both the acquisition itself and associated 
integration also increases. 

Loss of revenue, reduced profitability and reduced growth 
from failure to maintain our competitive positioning, or to 
increase or maintain market share

 › Continued focus on Marketing Excellence, to ensure we stay 
attuned to changing consumer preferences, and to maximise 
the value of our marketing campaigns

Failing to identify and exploit new geographic markets for 
our products

 ›

 ›

Loss of revenue, and potential reputational damage from 
counterfeit product reaching the market, which may not have 
been subject to the same rigorous quality and safety testing  
as genuine products

 › Depending on its severity, this could also potentially impact 

our share price, cash flow and covenant compliance

Increasing focus on innovation and development activities

Roll-out of Digital Excellence training across our 
marketing teams

 › Maintaining close working relationships with our distributors

 › Ongoing monitoring and forecasting of sales, costs, profits,  

and cash flows

 › Head of Brand Protection, brand protection strategies, support 

from external experts

 ›

Product or claims innovation strategies, to pre-empt 
patent expiration

 ›

Sustaining investment in brand promotion

 › Acquisitions fail to deliver expected benefits – due to overly 
optimistic forecasts, unidentified risks/poor evaluation of 
identified risks during due diligence, or as a result of failings in 
the integration process, resulting in integration taking longer/
costing more than was originally anticipated

 › Distraction cost to the business from acquisition 

evaluation activities

 › Maintaining an active presence and continuing to grow our 
reputation in the M&A market, to ensure a good pipeline 
of opportunities

 › Ongoing refinements to our acquisition evaluation process

 ›

 ›

Experience gained from having completed multiple deals

Engage experienced legal, regulatory and financial experts  
to assist with the due diligence process

40

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties continued

Links to strategy:

Organic growth  
– key brand potential

Trends:

Investing in people

Risk has increased versus last year

Risk has not changed materially since last year

Complementary acquisitions

Acting responsibly

Risk has reduced versus last year

Operational risks

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

3.  Product safety

Risk of an adverse reaction to one of our products constituting a 
safety risk for consumers.

 ›

The Group produces and sells a wide range of medicines, medical 
devices, food supplements and cosmetics. There are inherent risks 
that some of these products could cause adverse reactions. 

Products have to be withdrawn from sale and we may have 
legal liability to those injured by the product, potentially 
damaging our reputation, and compromising our future 
performance. In an extreme scenario, this could impact our 
liquidity position or even solvency

4.  Supply 

disruption

Disruption to the continuity of supply as a result of our inability to 
procure critical ingredients, due for example to geopolitical events, 
logistics failures, or reliance on a single site of manufacture. 

 › Manufacturing, sourcing, or distribution issues, including an 
inability to increase production volumes to meet demand, 
impinges on our potential sales and has the potential to 
compromise our future performance and, in an extreme 
scenario, cash generation

 › Dedicated in-house Quality function, which carries out regular 

supplier audits

 › Adverse event reporting and signal management for all 

medicine products – generally, the Group’s products are  
well-tolerated, and many have been in existence for decades

 › Maintenance of necessary regulatory approvals for all 

products in the markets we trade in

 › Maintenance of public and products liability insurance to 

provide an appropriate level of protection for the Company

 › Maintaining close working relationships with our key 
suppliers, to ensure we have early visibility of any  
potential issues

 ›

 ›

 ›

Ensuring we maintain adequate stocks of critical ingredients 
and of finished goods, to enable us to cushion the impacts of 
any disruption in the supply chain

Forward booking transportation, to minimise the impacts of 
any disruption to logistics provision – for example due to 
geopolitical and economic events

Putting in place dual sourcing arrangements for key products, 
to mitigate against manufacturer failure/inability to supply to 
meet sales demand

 › Where possible, and cost-effective, the potential financial 
impact of supply chain disruption is mitigated by insurance

41

Alliance Pharma plc – Annual Report and Accounts 2021 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties continued

Operational risks continued

Links to strategy:

Organic growth  
– key brand potential

Trends:

Investing in people

Risk has increased versus last year

Risk has not changed materially since last year

Complementary acquisitions

Acting responsibly

Risk has reduced versus last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

5.  Business 
systems

Failure to maintain and develop business systems and technology 
which adequately supports business processes, organisational 
infrastructure, and strategic growth ambitions, and enables us to 
manage any business continuity risk from unforeseen events.

The business is highly dependent on multiple IT systems – and 
systems failure as a result of a business continuity event could 
have a significant impact on the business’ ability to continue to 
operate effectively.

 ›

Loss of income or late market reporting as a result of a 
business continuity event causing loss of access to key 
resources, systems, and/or data. This could also potentially 
result in compliance failure, loss of control and an inability 
to trade

 › Quality of data degrades as a result of not effectively 

managing data shared across multiple systems, leading to 
poor decision-making and increased transactional errors

6.  Cyber security

Risk that the integrity, confidentiality and availability of our data 
and third-party information which we hold is compromised through 
cyber-attacks.

We hold significant amounts of confidential data relating to our 
products, our commercial activities, our financial transactions and 
all other aspects of our business operations in electronic format, 
making it susceptible to being compromised through cyber-attacks.

We also hold significant amounts of confidential data on our 
customers and employees, some of which is collected via our 
transaction processes, and so includes their financial information 
in addition to other personal data, which is similarly at risk of 
loss, corruption, or unauthorised dissemination as a result of a 
successful cyber-attack. 

 ›

 ›

 ›

Reputational impact if we suffered a major loss of personal 
data as a result of a successful cyber-attack

Financial loss, data loss, or reputational damage due to fraud 
perpetrated through a successful social engineering attack

Financial transactions being rerouted fraudulently because 
sensitive transactional data is given away

 › Data destruction or ransom as a result of a malicious link 

being clicked

 ›

 ›

 ›

The successful implementation of the ERP system has improved 
the internal control environment

Improved change control/change management processes to 
better protect the integrity of our master data

IT Steering Group in place to maintain oversight of core 
systems and lead on changes required as a result of systems 
development or regulatory changes

 ›

Business continuity plans in place and under regular review

 › Use of anti-virus software, firewalls, and network segmentation

 ›

 ›

Ensuring all business software remains up to date, to provide 
additional in-built security

Implementation/review of incident management, business 
continuity and IT disaster recovery plans

 › Maintenance of appropriate physical and cyber-security 
measures to prevent unauthorised access to information

 ›

 ›

Provision of training and alerts to staff to ensure that they are 
aware of known risks

Engagement of third parties to review and recommend 
ongoing improvements to enhance IT security and resilience

42

Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties continued

Operational risks continued

Links to strategy:

Organic growth  
– key brand potential

Trends:

Investing in people

Risk has increased versus last year

Risk has not changed materially since last year

Complementary acquisitions

Acting responsibly

Risk has reduced versus last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

7.  People

Failure to attract and retain sufficient high-quality people to deliver 
the business’ strategic growth ambitions.

By virtue of its business model, Alliance has a high level of reliance 
on the skills and knowledge of its employees, many of whom 
have considerable sector experience or other specialist expertise, 
making them attractive to competitors and not always easy 
to replace.

As the business continues to scale and to expand its geographic 
presence, our requirements for high-calibre people continues 
to increase.

The increasing globalisation of our supplier base as a result 
of recent acquisitions has served to increase our exposure to 
risks around Environmental, H&S, Business Ethics, Supply Chain 
Security and Climate and increases the risk of failing to maintain 
sufficient oversight of our end-to-end supply operations associated 
with these areas. 

This is potentially a significant risk for Alliance, as our outsourced 
supply model has historically afforded only limited visibility of our 
end-to-end supply chain. 

8.  Supply chain 
management

Compliance risks

 ›

 ›

 ›

 ›

The loss of key employees could potentially weaken the 
Group’s operational/management capabilities, potentially 
impeding its ability to grow

 › Maintaining competitive incentive and reward structures, 

which remain attractive to existing employees and enable us 
to continue to attract high-quality applicants for new roles

Loss of continuity/loss of knowledge as a result of employee 
replacement, leading to operational inefficiencies

Potential lack of required skills and expertise to support the 
continued growth of the business, its systems, procedures, 
and processes

 › Clearly defined roles and responsibilities supported by 

documented systems and procedures to provide a level of 
continuity in the event an employee leaves the Group

 › Maintaining relationships with a number of international and 
local recruitment agencies to ensure we are able to find and 
recruit good quality employees

 › Maintaining a balance between permanent and contract heads 

to increase flexibility, particularly for project-based work

Potential reputational damage, loss of product supply and loss 
of revenues from failure to maintain sufficient oversight of our 
end-to-end supply operations

 ›

The implementation our Know Your Supplier (‘KYS’) 
programme, partnering with a market-leading data analytics 
provider, to improve the visibility of potential ‘red flags’ in 
our supply chain. This enables us to align compliance and 
escalation processes to facilitate timely remediation of issues

 › Our Know Your Customer (‘KYC’) programme, to bolster our 

customer qualification and approval processes

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

9.  Product 

regulations

Risk of non-compliance with product classification regulations 
and registration requirements, including relevant internal/external 
quality regulations and requirements, across all territories in which 
our products are manufactured and/or sold.

 ›

Product regulations are continually being updated, new 
requirements introduced (e.g. Medical Device Regulations), 
or product classifications changed.

In a number of territories our product registrations are maintained 
by local distributors in order to comply with local regulatory 
requirements, creating an added layer of complexity.

Some of our products may not gain regulatory approval or 
could face the risk of having their regulatory status challenged 
or adversely altered. This could affect the Group’s ability to 
launch new products or maintain sales of its current products 
in current jurisdictions or pursue further geographic expansion

 › Non-compliance with product classification regulations/

registration requirements may result in product having to be 
withdrawn from the market, with a consequential loss of sales

 ›

If compliance issues cannot be remediated, this could 
lead to cessation of product supply, or limitation of 
market opportunities

 › Allocation of sufficiently experienced internal resource to 

support the regulatory approval of products, including any 
extensions to other markets

 › Maintenance of regular discussions with local regulatory 
advisers to monitor any products that may be subject 
to challenge

43

Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties continued

Compliance risks continued

Links to strategy:

Organic growth  
– key brand potential

Trends:

Investing in people

Risk has increased versus last year

Risk has not changed materially since last year

Complementary acquisitions

Acting responsibly

Risk has reduced versus last year

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

Risk of non-compliance with relevant laws and regulations in all 
countries in which we operate, including anti-corruption laws, 
data privacy laws, competition laws, accounting, taxation and 
listing regulations.

As the scope and scale of our business operations increases, 
we face an increasingly complex compliance burden. The level 
of legal and regulatory requirements to which we are subject 
continues to increase, and also the penalties for non-compliance, 
so it is vital that we are able to effectively manage all the various 
aspects of our compliance risk.

As we enter new territories and overseas markets, we become 
exposed to increased bribery, anti-slavery, and corruption 
risks. Likewise, as the Group expands its operations, the VAT 
and general tax environment in which it operates becomes 
more complex and the risk of incorrectly reporting and paying 
relevant taxes increases. 

 ›

The Group has ongoing regulatory requirements 
(pharmacovigilance etc.) which could, if not adhered to, lead 
to substantial fines and impact on the Group’s ability to sell 
certain products. Likewise, we may incur penalties for non-
compliance as a result of adverse findings from regulatory 
inspections, which may potentially impact on the sales of our 
products, damage our brands and our reputation

 ›

Bribery, anti-slavery, and corruption all carry their own 
penalties, and reputational damage

 › A failure to abide by data protection rules or incur a breach of 
data security could also pose a financial and reputational risk 
to the Group

 ›

 ›

Breaches of VAT and taxation rules also carry a risk of interest 
and penalties becoming payable

Infringement Decision by the CMA relating to alleged anti-
competitive agreement would, in the event that the Company’s 
appeal is not successful, lead to a fine of up to £7.9m

 › Continuing oversight of corporate compliance by in-house 

Company Secretarial function

 ›

 ›

 ›

Introduction of the new ERP system will assist with supply chain 
management and VAT reporting

Training made available to all employees on anti-bribery, 
anti-money laundering, competition law, market abuse, 
modern slavery, sanctions, tax evasion and GDPR

Engagement of third-party experts in our overseas territories 
to help us ensure compliance with local rules and regulations

 › Wide-ranging induction process for new starters to ensure 

they understand their individual, and the Group’s, obligations 
in relation to matters such as adverse event reporting

 › Notice of appeal against the infringement decision will be 

filed. Ongoing work with expert legal team to ensure that the 
Company’s appeal is as robust and effective as possible to 
give the company the greatest chance of succeeding

10.  Legal and 
compliance

Financial risks

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

11.  Foreign 

Movements in FX rates adversely impact financial performance.

 › Adverse movements in Sterling exchange rates vs Euro, US dollar, 

 ›

exchange risk

The Group earns a proportion of its revenues and profits in 
currencies other than Sterling (principally Euros, US dollars and 
Hong Kong dollars), but accounts for the business in Sterling. The 
reporting of revenues and profits is therefore subject to volatility 
due to changes in exchange rates.

Due to the acquisition of Biogix, which earns revenues and profits in 
US Dollars, this risk has increased since last year.

The change in CBEC distributor in 2021, has increased the Group’s 
exposure to Hong Kong dollars.

Hong Kong dollar and other currencies

The Group’s funding structure, with borrowings denominated 
in Sterling, Euros and US Dollars, provides a natural hedge to 
some of these exposures

 ›

The Group has a risk management policy to hedge up to 75% 
of its estimated future foreign currency EBITDA exposure for 
up to 18 months at any given point in time. The Group uses 
forward foreign exchange contracts to implement this policy 
which are generally designated as cash flow hedges

44

Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Principal Risks and Uncertainties continued

Links to strategy:

Organic growth  
– key brand potential

Trends:

Investing in people

Risk has increased versus last year

Risk has not changed materially since last year

Complementary acquisitions

Acting responsibly

Risk has reduced versus last year

Other risks

12.  Pandemics, 
geopolitical 
and other 
worldwide 
events

Emerging risks

13.  Environmental  
climate change

Risk description and relevance

Potential impacts

Key mitigating activities

Trend

In common with most other businesses, we will always be at 
risk from extreme and unexpected global events affecting our 
ability to operate. This could be an event that affects our people, 
our operational sites, our IT systems, or any other aspect of 
our business operations. This was the case with the COVID-19 
pandemic which surfaced in 2020, and which is now being 
managed in accordance with latest guidance and advice.

More recently, the escalation of geopolitical events in Europe 
could cause supply chain disruption within the business and  
subject us to economic uncertainty.

 ›

 ›

 ›

Reduction in revenues/profitability and/or failure to achieve 
expected growth due to reductions in demand or potential 
supply issues. Any significant impact on the Group’s revenues 
and profitability could potentially affect the Group’s ability to 
comply with its borrowing covenants

Pressure on sourcing and supply chain could lead to (i) an 
increase in the cost of transportation, raw materials and goods 
in general (ii) a reduction in availability of certain materials 
both of which could in turn impact profitability

Increased costs/reduced demand for goods due to weaker 
economic growth and higher inflation

 › General inflationary pressures being experienced by the 
wider business community will lead to increased pressure 
on workforce costs and rewards, which in turn could 
impact profitability

 ›

Regular review and updating of demand forecasts to 
understand and mitigate any potential adverse effects  
on revenues, supported by our recently improved  
S&OP processes

 › Maintenance of close working relationships with suppliers  
and distributors; ongoing monitoring for any signs of distress

 › Keeping abreast of global events and economic 

conditions in the territories we operate to ensure risks are 
monitored accordingly

Risk description and relevance

Potential impacts

Key mitigating activities

Risk to the longer-term viability of the business due to the impacts 
of environmental and climate change, both the direct impacts, 
e.g. the severity and frequency of adverse weather events and 
rising sea levels, and the indirect impacts, e.g. higher energy costs, 
infrastructure funding, which are likely to become increasingly 
prevalent, as we transition to a low-carbon economy.

 ›

These have yet to be determined

 ›

Increased business focus on environmental strategy and 
associated risks

 ›

Engagement of third party expert support

 › Creation of TCFD roadmap and emissions reduction targets

Trend

NEW

45

Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Governance

Chairman’s Introduction

Board of Directors

Governance

Nomination Committee Report

Audit and Risk Committee Report

Remuneration Committee Report

ESG Committee Report

Task Force on Climate-related Financial 
Disclosures (TCFD)

Directors’ Report

47

48

50

56

60

65

76

78

80

46

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Chairman’s Introduction

Dear shareholders  
and colleagues, 

A warm welcome to this year’s report on 
governance where I as your Chairman 
provide an overview of the Group’s 
governance arrangements. The Board 
believes governance is central to delivering 
on our strategy and helps ensure the 
successful operation of our business.

Last year, in adapting to life with the 
pandemic, we were able to build a stronger, 
more connected, and resilient business. As 
we all settle into a world where the pandemic 
seems to be very much a part of life, the 
business likewise has adapted and responded 
to support its customers, suppliers, employees 
and shareholders. The safety, health, and 
wellbeing of our employees continues to be of 
paramount importance and we have further 
improved our technology and infrastructure 
to provide safe ways of working, thereby 
keeping disruption to a minimum.

Following the acquisition of Biogix Inc.,  
the business has worked hard on integration 
and continues to build strong foundations 
to ensure it can grow its Consumer 
Healthcare portfolio.

In April 2021, Nigel Clifford resigned from 
the Board and, following a rigorous search 
and recruitment process, we were pleased to 
welcome Kristof Neirynck as a Non-executive 
Director on 1 December 2021.

Kristof brings with him his experience 
in international Consumer Healthcare, 
Marketing, Digital Transformation and 
Innovation. Further information about Kristof 
can be found in his biography on page 49.

As a company admitted to AIM, our 
governance is underpinned by the Quoted 
Companies Alliance (QCA) Corporate 
Governance Code 2018 (the ‘QCA Code’). 
During the year, we have complied with the 
principles of the QCA Code and details of 
how we have done so can be found in the 
governance section of the Company’s website.

The sustainability agenda continues to be 
progressed by the business with oversight 
from the newly formed ESG Committee. 
You can read more about the work of the 
Committee on page 76.

This year’s AGM will be held at 10.00am 
on 18 May 2022. Further details can be 
found in the Notice of AGM accompanying 
this Report.

The Board would like to thank all 
shareholders and colleagues for their 
continued support, and we look forward to 
continuing with our good work during 2022.

David Cook
Chairman

30 March 2022

47

“ Good governance practice 
continues to remain a priority 
for the Board as we continue to 
work together to deliver value 
to our shareholders”

Alliance Pharma plc – Annual Report and Accounts 2021 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Board of Directors

Committee Membership Key

Audit and Risk Committee

Nomination Committee

Remuneration Committee

ESG Committee

C

Committee Chair

David Cook
Independent Non-executive Chairman
Date joined

Peter Butterfield
Chief Executive Officer

Andrew Franklin
Chief Financial Officer

David joined the Board of Alliance as a Non-executive Director in 2014 and  
was appointed Chairman of the Board on 1 March 2018. 

Peter was previously the Company’s Deputy Chief Executive Officer and was 
appointed to his present office as Chief Executive Officer on 1 May 2018 having 
joined Alliance in 2010 as an Executive Director. 

Andrew joined Alliance in September 2015 from Panasonic Europe Ltd, where he was 
General Manager, European Tax and Accounting.

Qualifications

David graduated in Chemistry at the University of Oxford and is a  
Chartered Accountant.
Experience

Peter holds an honours degree in Pharmacology from the University of Edinburgh.

Andrew holds an honours degree in Civil Engineering from the University of  
Wales, Cardiff.

He is currently Chief Financial Officer and an Executive Director of Ellipses Pharma, an 
international cancer drug development company, and was previously Chief Financial 
Officer and Chief Business Officer of Biotie Therapies Corp, a drug development 
company quoted in Helsinki and on NASDAQ. He has previously held senior financial 
positions with Jazz Pharmaceuticals International, EUSA Pharma and Zeneus Pharma. 

Peter has over 20 years’ experience in the life sciences sector and strong leadership 
experience gained in a variety of contexts. Peter joined the Board of Alliance in 2010 
with the acquisition of Cambridge Laboratories where he spent five years, latterly as 
UK Commercial Director. Prior to joining Cambridge Laboratories, Peter spent six years 
at GlaxoSmithKline in a variety of marketing and sales roles.

David has extensive experience of financial and general business management 
(including the implementation of buy and build strategies) in the life sciences sector,  
of financing those businesses and managing investor relations across a number of  
stock markets globally.

Committee membership

C

C

View the Nomination Committee Report on page 56

View the ESG Committee Report on page 76

From 2010 to 2012 Andrew was Finance Director and Company Secretary of 
Genzyme Therapeutics Ltd, the UK and Ireland subsidiary of Genzyme Corporation. 
Prior to that, he gained 12 years’ pharmaceutical experience with Wyeth in a variety  
of senior financial positions. 

Andrew is a Fellow of the Institute of Chartered Accountants in England and Wales with 
extensive experience of financial management of international businesses, including 
significant prior experience in life sciences companies.

48

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

Board of Directors continued

Committee Membership Key

Audit and Risk Committee

Nomination Committee

Remuneration Committee

ESG Committee

C

Committee Chair

Jo LeCouilliard
Independent Non-executive Director
Date joined

Richard Jones
Independent Non-executive Director

Kristof Neirynck
Independent Non-executive Director

Jo joined Alliance as a Non-executive Director on 1 January 2019.

Richard joined Alliance as a Non-executive Director on 1 January 2019.

Kristof joined Alliance as an Independent Non-executive Director on 1 December 2021.

Qualifications

Jo graduated in Natural Sciences from Cambridge University and is a  
Chartered Accountant.

Richard has a degree in Engineering from Newcastle University and is a  
Chartered Accountant.

He graduated as a Master of Science in Electronic Engineering from the University of 
Ghent, Belgium.

Experience

Jo has 25 years’ healthcare management experience gained in Europe, the US 
and Asia. Much of her career has been in pharmaceuticals at GlaxoSmithKline 
where, amongst other roles, she headed the US vaccines business and Asia Pacific 
Pharmaceuticals business and led a programme to modernise the commercial model. 
She was previously Chief Operating Officer at the BMI group of private hospitals in the 
UK. She was Non-executive Director at Frimley Park NHS Foundation Trust in the UK, 
Duke NUS Medical School in Singapore and Cello Health plc.

She is currently a Non-Executive Director at UK listed company Circassia Group plc 
and is also on the Board of Recordati S.p.a and Indivior PLC.

Richard is Chief Financial Officer at Medica Group PLC, the UK’s leading teleradiology 
provider. Prior to this, he was CFO and a Board member of US listed Mereo BioPharma 
Group PLC, a biopharma company developing a range of products in bone, endocrine 
and respiratory therapies with a focus on rare diseases. 

Richard joined Mereo from UK AIM listed Shield Therapeutics plc where he was  
CFO and Company Secretary from early 2011 having initially joined the Board as 
a Non-executive Director in 2010. At Shield he had a leading role establishing the 
finance operations and guiding Shield through its 2016 IPO. 

He has a background in investment banking, having held senior positions at Investec 
and Brewin Dolphin Securities, where he advised healthcare clients on a wide range  
of transactions including IPOs, M&A and fundraisings.

Kristof joined the Board on 1 December 2021. He is global Chief Marketing Officer at 
Avon Cosmetics and brings 20 years of experience in General Management, Marketing, 
Digital Transformation, and Innovation, having carried out roles in Fast Moving 
Consumer Goods/Consumer Packaged Goods, Luxury and Retail sectors across multiple 
geographies. He is well versed in operating across an omnichannel model, combining 
bricks and mortar retail, e-commerce and direct to consumer experience.

Kristof joined Walgreens Boots Alliance in 2015 and in 2017 became their Chief 
Marketing Officer for their Global Brands division where he had responsibility for a 
$4bn sales portfolio of more than 20 of their owned brands in Beauty and Consumer 
Healthcare. Prior to this, Kristof held leadership roles at P&G’s Prestige, Laundry and 
Feminine Care global divisions, having started his career in 2002 at Procter & Gamble 
in Belgium before moving to Procter & Gamble International in Switzerland in 2004.

Committee membership

C

View the Remuneration Committee Report on page 65

C

View the Audit and Risk Committee Report on page 60

49

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Governance

Key activities of the Board and its Committees
Throughout the year the Board received regular updates on, and considered, strategy, the commercial and financial performance of the business, scientific affairs and operations, people and 
infrastructure and legal and governance. In addition to these standing items, other business considered by the Board and its Committees is set out below.

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug*

Sep

Oct

Nov

Dec

Strategic planning 
Strategy planning, review of Group strategy, presentations from business and functions

2022 Budget 
Presentations and budget approval

Corporate development 
Review of acquisition opportunities and integration of Biogix Inc.

Business reviews 
Mainland Europe, Asia Pacific, US, various product and brand reviews, brand protection, Great Place to Work

Investor engagement and broker presentations 
Full and half year results webcast presentations, analyst calls and investor road-shows, private client fund manager meetings,  
one-to-one calls and AGM, and presentations from brokers 

Company results, trading statements and dividends 
Annual Report and Accounts, dividend policy and declarations

Nomination Committee  
Board composition and Committee membership, succession planning, NED recruitment, terms of reference, bonus proposal  
for 2022

Remuneration Committee 
Review of salary proposals, 2020 corporate bonus awards, Company share option awards, 2021 corporate bonus scheme, 
objectives and targets, terms of reference

Audit and Risk Committee  
Key accounting estimates and judgements, significant accounting policies, annual audit process and fees, external auditor, internal 
audit, foreign currency and hedging, US accounting post acquisition of Biogix Inc., ERP accounting and accounting treatment of 
CMA investigation

ESG Committee 
2021 and 2022 sustainability framework and initiative, investor engagement, disclosure and accounting metrics, carbon action 
plan and environmental strategy, corporate website disclosures, terms of reference

Governance & Legal 
Includes the review of risk management framework, Board Effectiveness Review, Governance reporting, review of Articles of 
Association, AGM Notice, D&O insurance, litigation, Modern Slavery Statement, review of gender pay

* 

 Although there is no scheduled meeting in August, a management pack is circulated.

50

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Governance

Financial Statements

Additional Information

Governance continued

The role of the Board 
The Board is responsible for the Group’s 
vision, business model and strategy. Together, 
the Directors are responsible for providing 
effective leadership to promote the long-term 
success of the Company. 

 › maintaining the policy and decision-
making process through which the  
strategy is implemented;

 › checking that necessary financial and 
human resources are in place to meet 
strategic aims;

Each year the Board holds a two-day 
strategy planning meeting at which the 
SLT and other senior employees present 
their proposals. From this session, the 
Group’s strategic plan and business model 
is agreed. The CEO is responsible for the 
implementation of the strategy and reports to 
the Board formally at a half year review. The 
strategy is communicated to all employees 
by the management teams through breakfast 
briefings and online presentations. Further 
information on how the Company delivers the 
strategy to promote long-term growth can be 
found on pages 17 to 22 and in its business 
model on page 16.

There is a formal list of matters reserved for 
the Board, which may only be amended by 
the Board and is available on our website.  
The Board’s key responsibilities include:

 › providing entrepreneurial leadership  

within a framework of good governance 
and sound risk management;

 › monitoring performance against key 
financial and non-financial indicators;

 ›

 ›

responsibility for risk management and 
systems of internal control; and

setting values and standards in corporate 
governance matters. 

Corporate culture and business conduct
Our culture is underpinned by a clear set of 
values (PRAISE), which help guide decision- 
making at all levels in the business. 

The Board expects the business to foster 
relationships and operate high standards 
of business conduct. The Board reviews 
and approves the Group’s policies which 
have been implemented and communicated 

internally and externally to those who are 
expected to adhere to them. For example, this 
includes policies on diversity and inclusion, 
the prevention of bribery and corruption, 
fair competition and anti-slavery and human 
trafficking. Further information about our 
policies can be found in ‘Business Ethics‘  
on our website.

Engagement with shareholders
The Board and its Committees recognise that 
to meet its responsibilities to shareholders and 
other stakeholders, it is important to ensure 
effective engagement with, and encourage 
participation from, these parties. The Board 
factors the needs and concerns of all the 
Company’s stakeholders into its discussions 
and decision-making, having been made 
aware of the needs, interests, and any 
impact of such decisions on the Company’s 
stakeholders. Visibility and awareness are 
further increased through senior management 
who have collective responsibility for 
communicating and engaging with specific 
stakeholder groups. This includes making sure 
that the business as a whole upholds its values 
and monitors behaviour for acceptability.

Recently, the Company invested in its Investor 
Relations (IR) by appointing a new Head of IR 
and Corporate Communications.

Further information on our dialogues and 
engagement with shareholders and other 
stakeholders can be found on pages 34  
and 53.

Throughout the year, the CEO and CFO meet 
with potential and existing investors and they 
feed back to the Board the key summary 
points from their meetings. In addition to these 
meetings, there were 57 scheduled meetings 
held as part of the Company’s investor road-
shows for the annual 2020 and half-year 
2021 results.

The Board is provided with an analysis of 
the Company’s investor base at each Board 
meeting and research notes by sell-side 
analysts are circulated to all Directors. 
Furthermore, analysts’ notes, and brokers’ 
briefings are received and considered by the 
Board in order to ensure, as far as possible, 
a clear and up-to-date understanding of 
investors’ views. Information on investor 
sentiment is also provided to the Board by the 
Company’s brokers and financial PR advisers.

51

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Governance continued

A list of the Company’s major shareholders 
can be found in the investor section of our 
website, and a list of notifiable holdings can 
be found on page 80 of the Directors’ Report. 
These are regularly updated following 
the formal notification of movements to 
the Company.

The Board and its Committees 
The Board currently comprises six 
Directors, being the Chairman, three further 
independent Non-executive Directors and 
two Executive Directors. Independence on the 
Board is reviewed and confirmed annually by 
the Nomination Committee. 

The Company further communicates with 
shareholders through its Annual Report 
and Accounts, half-year announcements, 
trading updates and at the Company’s 
AGM. Such reports as well as other relevant 
announcements and related information  
are all available on the Group’s website, 
www.alliancepharmaceuticals.com. The 
website also offers a facility to sign up for 
email alert notifications of Company news 
and regulatory announcements. 

With employees 
The Board receives regular updates on 
People and employee engagement at its 
meetings. This includes briefings following 
surveys, organisational structure and other 
positive initiatives to support health and 
wellbeing. From time to time, employees 
are invited to attend various Board and 
Committee meetings to present on key 
operational and strategic matters. 

The Chairman
The Chairman, David Cook, has primary 
responsibility for leading the Board and 
facilitating the effective contribution of all 
members to meetings. He maintains a strong 
focus on governance to ensure good practice 
is embedded in the business with good flows in 
communication and reporting. He has regular 
dialogue with the CEO to ensure the business 
and the management team receives the 
support from the Board necessary to progress 
the strategy. 

The Chairman also meets with the Non-
executive Directors on their own at least 
once a year and further meets with them 
as part of the Board evaluation process. 
Shareholders have an opportunity to engage 
with the Chairman and the Board at the 
Company’s AGM. 

The Chief Executive Officer (CEO)
The CEO, Peter Butterfield, is responsible for 
the day-to-day running of the business and 
implementation of the Group’s strategy. He is 
supported by the SLT who have management 
responsibility for the business operations 
and support functions. Relevant matters are 
reported to the Board by the CEO and, as 
appropriate, the CFO and other members 
from the SLT.

The Non-executive Directors
Non-executive Directors are required to 
commit the time necessary to fulfil their role. 
Their role is to:

 › Provide oversight and scrutiny of the 

performance of the Executive Directors;

 › Constructively challenge to help develop 
and execute on the agreed strategy;

 › Satisfy themselves as to the integrity of 
the financial reporting systems and the 
information they provide;

 › Satisfy themselves as to the robustness of 

the internal controls;

 › Ensure that the systems of risk management 

are robust and defensible; and

 › Review corporate performance and 
the reporting of such performance 
to shareholders.

Each of the Non-executive Directors sits on 
at least three of the Committees ensuring 
that between them they have a role in 
determining the pay and benefits of the 
Executive Directors and in the planning of 
Board succession, including the appointment 
and, if necessary, removal of Executive 
Directors. Three independent Non-executive 
Directors, all of whom have an accountancy 
qualification, sit on the Audit and Risk 
Committee, enabling them to review internal 
controls and financial reporting matters. 
They have a direct relationship with the 
external auditors.

Each Non-executive Director is appointed for 
an initial term of five years, subject to annual 
re-election by shareholders at the AGM. 
Their appointment term may be renewed by 
mutual agreement. 

52

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Governance continued

Stakeholder engagement and section 172

Engaging with the Company’s stakeholders is 
well embedded in the business as we continue 
to look after our relationships with employees, 
customers and suppliers and consumers and 
the wider communities.

Promoting long-term success — s.172 
Companies Act 2006
The powers and duties of the Directors are 
determined by legislation and the Company’s 
Articles of Association. The Directors are 
aware and mindful of their duties and 
obligations under s.172 of the Companies Act 
2006. Directors are required to act in good 
faith. Discussions give due consideration to the 
impact of decisions on the Group’s strategy 
and values, stakeholders and the Directors are 
provided with written reports, market reviews, 
guidance, and presentations and briefings 
from both internal members of staff and 
external advisers as part of the process. 

Decisions are taken with a view to 
promoting the success of the Group and 
having considered the likely and long-term 
consequences for stakeholders concerned. 

Under s172 Companies Act 2006, a 
company’s directors have a duty to discharge 
their responsibilities having regard to:

a)  the likely consequences of any decision  

in the long term

b)  the interests of the company’s employees

c)   the need to foster the company’s business 
relationships with suppliers, customers  
and others

d)  the impact of the company’s operations  
on the community and the environment

e)   the desirability of the company maintaining 

a reputation for high standards of 
business conduct

f)   the need to act fairly as between members  

of the company

Case study 1

Improving brand protection and distribution of products
During the year the Board receives regular updates on what the business is doing to 
protect its brands to ensure that opportunities are maximised to key geographical regions 
of the business. Plans put forward considered various stakeholder needs, including:

 ›

Investing in resources and the development of existing skills and expertise both in the 
UK and in APAC.

 › Maximising benefits and financial value to the business and shareholders.

 ›

Investing in the detection and prevention of counterfeit products to ensure product 
quality and consumer safety.

 › Reviewing and engaging key distribution partners and channels to protect the integrity 

of the supply of products to customers and consumers.

Case study 2

ESG is very much at the heart of Board decisions
The Board continues to press forward with its focus on Sustainability, having established an 
ESG Committee at the beginning of 2021. A dialogue with key institutional shareholders 
formed part of a stakeholder engagement programme to ascertain and understand their 
views and approach. With a focus maintained on shareholders, people, customers and 
suppliers, and our impact on the wider community and planet, stakeholder needs are very 
much at the centre of a progressive strategy. During the year:

 › External consultants have been engaged to support, help and inform the development 

of our sustainability strategy and framework and broaden understanding.

 › An active dialogue was maintained with the investor community.

 › Feedback was provided to the Board following open workshops with employees to 

better understand their views on ESG and climate-related matters. These sessions led  
to the Sustainability Forum.

 › Engagement with the Remuneration Committee to ensure alignment with the Company’s 

reward and benefits strategy.

53

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Strategic Report

Governance

Financial Statements

Additional Information

Governance continued

Board

11 Board Meeting attendance – 91% attendance

Member

David Cook

Peter Butterfield

Andrew Franklin

Kristof Neirynck*

Jo LeCouilliard

Nigel Clifford*

Richard Jones

Role

Chairman

CEO

CFO

NED

NED

NED

NED

Status

Independent

–

–

Independent

Independent

Independent

Independent

Attendance

11/11

11/11

11/11

1/1

11/11

4/4

10/11

* 

 Kristof Neirynck joined the Board of Directors on 1 December 2021. Nigel Clifford resigned from the Board of Directors on 30 April 2021.

Board Committees 
The Board has delegated and empowered 
four Committees: a Remuneration Committee, 
a Nomination Committee, an Audit and Risk 
Committee and an ESG Committee. Each 
Committee has written terms of reference set 
by the Board, which are reviewed annually 
and are available on the Company’s website. 

Membership of each Committee is determined 
by the Board on the recommendation of the 
Nomination Committee. Executive Directors 
are only permitted to be members of the 
ESG Committee. 

Each Committee Chair reports to the Board 
on the activities considered and determined 
by the relevant Committee. A summary of the 
Committees’ responsibilities and their work 
during the year can be found in the reports from 
the Committees appearing later in this section.

Board attendance, support and 
meeting management

Attendance schedule
In leading and controlling the Company, the 
Directors are expected to attend all meetings. 
The Board and its Committees meet regularly 
on scheduled dates. This includes a two-
day strategy meeting in each year which is 
also attended by all senior executives of the 
Group, the purpose of which is to review 
progress in delivering agreed plans and to 
develop and settle the Group’s business plans 
and long-term strategic targets and set the 
framework for the achievement of those goals. 

The Board held 11 scheduled meetings, and 
three unscheduled meetings, during the year. 
Meetings follow a clear agenda, supported 
by written reports and presentations from both 

internal members of staff as well as external 
advisers and consultants. Three unscheduled 
meetings of the Board were called to deal 
with non-routine business.

Meeting management
The Company Secretary is secretary to the 
Board and the Board’s Committees. On behalf 
of the Chairman, the Company Secretary is 
responsible for ensuring that all Board and 
Committee meetings are conducted properly 
and that the Directors are properly briefed on 
any item of business to be discussed. He has 
a direct line into the Chairman on all matters 
relating to governance and is responsible for 
ensuring governance, legal and regulatory 
compliance is considered, recorded 
and implemented. 

Procedures are in place for distributing 
meeting agendas and reports so that they are 
received in good time, with the appropriate 
information. Ahead of each Board meeting, 
the Directors each receive written reports 
updating on strategy, finance, including 
monthly management accounts, operations, 
commercial activities, business development, 
risk management, legal and regulatory, 
people and infrastructure and on investor 
relations. Meeting papers are distributed 
via an electronic board portal.

The Directors may have access to 
independent professional advice, where 
needed, at the Group’s expense.

Director training and development
All the Directors are responsible for ensuring 
their skills and knowledge are kept up to date. 
This is done in varying ways but includes 
professional training, online training or 
attending seminars and webinars offered 
by advisers and consultancies. In addition, 
regular updates on corporate governance, 
legal or regulatory changes are also provided 
via reporting or through presentations to 
the Board.

Directors’ conflicts of interest
The Company has effective procedures in place 
to monitor and deal with conflicts of interest. 
Directors are required to notify the Company 
of any situation that could give rise to a conflict 
or potential conflict thereby compromising their 
independence and objectivity. Each member is 
required to disclose any such potential conflicts 
at the start of every meeting. The Board is fully 
aware of the other commitments and interests of 
its Directors, and changes to these commitments 
and interests are reported to and, where 
appropriate, agreed with the rest of the Board. 
Where any such conflict arises, the Board 
determines whether or not a Director can vote 
or be a party of the item under consideration 
in accordance with the Company’s Articles 
of Association.

The Board is satisfied that potential conflicts 
have been effectively managed throughout 
the year.

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Additional Information

Governance continued

The table below sets out the key focus areas arising from the 2022 review:

Areas of focus

Feedback and recommendations

Board planning framework 
and dynamics

The planning framework drives discipline and behaviours. The strong proximity of 
the Board and management is a real strength and there is always open and sensible 
discussion and challenge from Directors.

Focus on strategy

The strategy is well formulated. The Board continues to understand the impact of 
emerging trends and envision the longer-term plans. The recent appointment of Kristof 
Neirynck demonstrates the Board’s commitment to strategy by enhancing skills and 
capabilities in the area of consumer healthcare.

Performance and remit  
of Board Committees

Overall the Committees are chaired and run very well. The Remuneration, 
Nomination and ESG Committees need to ensure their work continues to evolve 
as the strategy develops, particularly in the areas of remuneration policy and 
succession planning.

Board engagement

There is good engagement with investors and the Board is to consider how it could 
engage with employees outside of surveys and presentations.

The next review in relation to 2022 is scheduled for early 2023.

Board effectiveness 
As required under the QCA Code, the 
Board continually monitors and improves its 
performance and evaluates its performance 
based on clear and relevant objectives. 
The Chairman evaluates the performance 
of the Board annually to offer Directors an 
opportunity to discuss their contribution in 
terms of their skills and experience as well 
as identifying areas for improvement or 
development to enhance the capabilities 
of the Board as a whole. The Nomination 
Committee reviews any outcomes affecting 
Board and Committee composition.

In last year’s Annual Report we set out the 
feedback from the 2021 review which 
focussed on four key areas including roles, 
contributions, and stakeholder engagement; 
meeting management and priorities; ambition 
and strategic planning and Board culture 
and dynamics.

Where necessary and helpful, the Executive 
and senior leadership team can maintain a 
dialogue with the Non-executive Directors 
and can contact each other freely. During the 
year, the progress made included:

 › The Board holding a dedicated two-
day face-to-face strategy meeting at 
which management teams delivered their 
presentations on their proposals for the 
short-to-medium terms plans for the business. 
Alongside this there was a mid-year meeting 
to review progress against the strategy.

 ›

Improved reporting to ensure there is the 
right balance of information to support 
decision-making. Meetings are held  
face-to-face where possible and the 
current Board schedule provides for  
some meetings to be held at our  
overseas offices. 

 › The Board is mindful of investors’ views 

and there is a good level of engagement 
through telephone meetings, road-shows, 
presentation days and responding to 
written requests for information. During the 
year, there was enhanced engagement 
with investors on ESG matters to 
understand their views. In addition, the 
Board recently approved the appointment 
of a new Head of Investor Relations and 
Corporate Communications and looks 
forward to hosting a Capital Markets  
Day in 2022.

The 2022 evaluation consisted of one-to-one 
meetings between the Chairman and each 
Director to discuss various matters relating 
to Board and Committee performance and 
their effectiveness. 

Each meeting was also attended by the 
Company Secretary, who obtained feedback 
from each Director on the Chairman. 

Results and outcomes were reviewed, 
summarised and circulated to Board members 
for discussion in February 2022. 

55

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Additional Information

Nomination Committee Report

Nomination
Committee 
Report

“As a growing Consumer 
Healthcare business we 
seek the very best skills 
and experience to help 
us achieve the Group’s 
strategic objectives”

Chairman’s statement
On behalf of the Nomination Committee 
(the ‘Committee’), I am pleased to introduce 
the Nomination Committee Report in which 
we set out the Committee’s responsibilities 
and report on the activities of the Committee 
during the year.

As a growing international Consumer 
Healthcare business it is critical that we 
employ the capabilities of and develop 
our people to help us continue to deliver 
on our strategy. We remain focused on 
understanding our framework on gender  
and ethnic diversity and inclusion, and 
succession planning across the business.

During the year much of the Committee’s 
focus has been on succession planning, Board 
composition, and the search and appointment 
of a new Non-executive Director.

On 1 December 2021, we warmly welcomed 
Kristof Neirynck to the Board and he was also 
appointed to the Nomination, Remuneration 
and ESG Committees. You can read 
more about our recruitment and induction 
processes on page 59 of this report.

David Cook
Nomination Committee Chairman

30 March 2022

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Nomination Committee Report continued

DIRECTOR

Peter Butterfield

Andrew Franklin

Kristof Neirynck

David Cook

Jo LeCouilliard

Richard Jones

ROLE

CEO

CFO

INED

INED

INED

INED

GENDER

FINANCE

CONSUMER 
HEALTHCARE

PHARMA

INTERNATIONAL

GROWTH

FINANCIAL  
MARKETS*

Board gender diversity

M

M

M

M

F

M

Male
83%

Female
17%

* 

 UK and overseas financial markets experience.

Diversity and inclusion
As part of a progressive plan, we review the 
skills on our Board and work with Group HR 
to ensure we identify any gaps. We talk about 
a range of areas such as diversity of thought, 
experience, gender, ethnicity, skills, nationality, 
and specific skills identified to strengthen and 
develop the knowledge base on the Board. 
When necessary we also engage and work 
with specialist recruitment consultants to 
help identify talent and search for potential 
candidates that meet our objective criteria. 

As a Board of a company admitted to AIM, 
we monitor the guidance and best practice in 
the market around the areas of gender and 
ethnicity, in particular the percentage targets 
set for FTSE main market listed companies. 

Should investors wish to discuss any aspects of 
the work of the Committee, I will be available 
to answer questions at this year’s AGM.

The Company’s Diversity and Inclusion Policy 
can be found on the Company’s website.

The role of the Committee
The Nomination Committee’s primary roles 
are to carry out a selection process for 
the appointment and reappointment of all 
Directors to the Board, and to review the 
structure, size and composition of the Board 
(including in terms of skills, knowledge, 
experience and diversity). The Committee 
also reviews the leadership needs of the 
organisation and monitors succession 
planning for both Board and senior executive 
roles. The framework of duties is set out in  
its Terms of Reference which are available 
on the Company’s website. Each year the 
Committee reviews its own performance  
and its Terms of Reference. 

Duties of the Committee
The duties of the Committee include:

 › Keeping itself informed about strategic 

issues and commercial changes affecting 
the Company.

Members of the Committee have access 
to the Company Secretary, who attends 
and minutes all meetings. To enable the 
Committee to discharge its duties effectively, 
the Company Secretary is responsible for 
ensuring the Committee receives high-
quality, timely information. The Chair of 
the Committee reports to the Board on its 
proceedings after each meeting on all matters 
within its duties and responsibilities and will 
make any recommendations to the Board it 
deems appropriate.

 › Reviewing the structure, size, and 

composition of the Board, including 
diversity, skills, knowledge, and experience.

 › Considering succession plans for Directors 

and other senior executives.

 ›

Identifying and nominating candidates to 
fill Board vacancies.

 › Evaluating the balance of skill, knowledge, 

experience, and diversity prior to 
commencing any appointment process.

 › Reviewing the results of the Board 
performance evaluation insofar as 
it relates to composition and time 
commitment of Directors.

 › Making recommendations to the Board on 
matters such as Committee membership, 
reappointment, and re-election of Directors.

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Additional Information

Nomination Committee Report continued

Attendance
During the year, the Committee held two scheduled meetings and reported on its activities to the Board.

Nomination Committee

2 Meetings – 100% attendance*

Member

Role

David Cook

Jo LeCouilliard

Kristof Neirynck

Nigel Clifford**

Richard Jones

Chairman

NED

NED

NED

NED

Status

Independent

Independent

Independent

Independent

Independent

Attendance

2/2

2/2

–

1/1

2/2

* 

 Additional ad hoc meetings were held during the year to deal with NED recruitment.

** 

 Resigned from the Board on 30 April 2021.

Committee membership
Appointments to the Committee are made by 
the Board. Only members of the Committee 
have the right to attend meetings. However, 
where appropriate, the Chief People and 
Infrastructure Officer and the CEO are invited 
to attend certain meetings of the Committee 
to support with discussions around succession 
planning and recruitment process.

Committee membership changes
Nigel Clifford stepped down from the 
Committee on 30 April 2021. With 
effect from 1 December, Kristof Neirynck 
was appointed a member of the 
Nomination Committee.

Activities of the Committee
Board composition
The Committee reviews any outcomes from 
the annual Board performance evaluation 
that relate both to composition and time 
commitment from Non-executive Directors. 
The Committee keeps under review the Board’s 
composition to ensure it provides a sufficiently 
wide range of skills and experience to enable 
it to pursue its strategic goals and to address 
anticipated issues in the foreseeable future. 
This process includes reviewing the mix of skills, 
sector experience and financial, public markets 
and international experience.

Being a global business, the Committee 
is aware of the benefits of diversity on the 
Board and at the senior management level. 

It remains committed to considering diversity 
when discussing appointments and succession 
plans. The Company and the Board always 
seek to search for, recruit and appoint the best 
available person based on aptitude and ability, 
regardless of gender, marital or civil partnership 
status, race, colour, nationality, ethnic or 
national origins, pregnancy, disability, age, 
sexual orientation, religion or belief.

NED search and appointment
During 2021, the Nomination Committee 
conducted a search and recruitment process 
followed a review of the skills, capabilities and 
experience on the Board. As an international 
consumer healthcare business with diverse 
products across many territories, the Board 
sought to recruit someone with close 
knowledge and extensive experience in the 
marketing of products in the healthcare sector, 
across several countries, particularly in the US, 
APAC and European regions. The Committee’s 
process was supported by the Chief People 
and Infrastructure Officer and the Company 
engaged the services of an external executive 
search and recruitment agency.

Following a recommendation by the 
Nomination Committee, the Board was 
pleased to announce the appointment of 
Kristof Neirynck as a Non-executive Director 
on the 29 June 2021. He took office on 
1 December 2021 and brings with him the 
addition of skills and experience in marketing, 
digital transformation and innovation gained in 
fast-moving consumer healthcare companies.

Board balance and independence
The Committee considers there to be an 
appropriate balance between Executive 
and Non-executive Directors on the Board, 
and following this year’s Board evaluation, 
members confirmed that discussions are 
not dominated by any one or small group 
of people when making decisions. Having 
considered the guidelines on independence, 
on appointment as Chairman, David Cook 
was independent and continues to be 
regarded by the Board as independent 
alongside Richard Jones, Jo LeCouilliard  
and Kristof Neirynck. 

Senior Independent Director (SID)
Each year the Nomination Committee 
considers whether it is appropriate to have 
a SID to act as a sounding board and 
intermediary for the Chairman or other Board 
members. As part of their review in 2021, it 
was concluded that the appointment of a SID 
is not necessary at this time, but the potential 
appointment will be kept under review.

External directorships
The Chairman and Non-executive Directors 
hold appointments as Directors and/or senior 
management on a small number of other 
companies, as detailed in their biographies 
on pages 48 and 49. It is considered that 
the Chairman and Non-executive Directors 
allocate sufficient time and commitment to 
fulfil their duties to the Company.

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Additional Information

Nomination Committee Report continued

Board appointments and  
succession planning
Succession planning
The Committee works closely with the Board 
and, with the support of the Chief People and 
Infrastructure Officer, develops strategies in 
support of progressive and orderly succession 
planning for Board and senior management. 
Planning includes consideration of the 
challenges and opportunities facing the 
Company and careful evaluation of the skills 
and experience needed on the Board in the 
future. When developing these plans, the 
Directors are mindful of the need for a more 
diverse executive pipeline to help increase 
diversity levels in senior positions.

Page 75 in the Remuneration Committee 
Report sets out the term of appointment for 
each Director. The nine year tenure of the 
Chairman will come to an end early 2023, 
after which he is no longer considered to be 
independent. Accordingly, the Committee 
has started to consider succession for the 
role and shareholders will be notified of any 
proposed changes as and when it would be 
appropriate to do so. 

Board appointments and induction
Whether as part of formal succession 
planning or to fill any Board vacancy that 
should arise, the Committee leads the 
process for the appointment of Directors. 
The Chairman does not chair the Committee 
when it is dealing with the appointment of 
his successor. 

Any appointment process follows a 
careful assessment of the balance of skills, 
knowledge and experience and diversity 
on the Board to identify capabilities that 
would enhance the Board and support the 
long-term strategy of the Group. The Chief 
People and Infrastructure Officer prepares 
a role description and capabilities required 
for the appointment. The services of an 
external recruitment agency are engaged 
to facilitate the search with instructions to 
consider candidates from a wide range of 
backgrounds. Potential candidates are also 
considered on merit and against objective 
criteria with due regard to the benefits of 
diversity, including gender, and time available 
to devote to the position. Potential candidates 
are required to disclose business interests that 
may result in a conflict of interest. 

From a short-list of suitable candidates, 
interviews are held with the Chairman of 
the Board, CEO and Chief People and 
Infrastructure Officer and other Board 
members. The Committee then recommends 
appointments to the full Board for their formal 
approval. New appointments are proposed 
to shareholders for approval at the next AGM 
following the first date of appointment. 

Annual re-election of Directors at AGM
In accordance with the Company’s Articles 
of Association, all Directors are subject to 
election or re-election by shareholders at 
the AGM. In line with good practice, the 
Committee recommended to the Board that 
all six Directors, being eligible, put themselves 
forward for annual re-election at the 
Company’s AGM. 

On appointment, all Directors receive a 
personally tailored induction. This includes 
meetings with members of the Board, 
members of the SLT, the Group General 
Counsel and Company Secretary, and 
presentations from key functions in the 
business. They are provided with an overview 
of the Group’s structure and operations and 
governance policies and receive copies 
of past Board minutes and reports via the 
electronic board portal. In addition, the portal 
holds other key corporate documents and 
information, for example, Matters Reserved 
for the Board, Committee Terms of Reference, 
the Company’s Articles of Association 
and the Directors’ and Officers’ liability 
insurance arrangements.

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Additional Information

Audit and Risk Committee Report

Audit and Risk
Committee 
Report

Chairman’s statement
On behalf of the Audit and Risk Committee 
(the ‘Committee’), I am pleased to introduce 
the Audit and Risk Committee Report. As a 
company admitted to AIM, we are guided 
by the QCA’s Audit Committee Guide and, 
when appropriate to do so, look to the UK 
Corporate Governance Code 2018 and to 
investor guidelines for best practice. 

In this report we set out the Committee’s 
responsibilities and report on the activities  
of the Committee during the year. 

At the start of the year, alongside our regular 
work carefully reviewing the Company’s 
annual financial statements, the associated 
accounting treatment and disclosures, efforts 
focussed on the integration of Biogix Inc. 
following its acquisition on the 29 December 
2020. The Committee carried out a post-
acquisition accounting review of Biogix Inc., 
which included a review of the independent 
audit conducted in respect of the Company’s 
financial statements prior to acquisition, 
significant judgements and estimates used 
in considering the impact of the acquisition 
under IFRS 3 (‘Business Combinations’) 
and the appropriateness of the disclosures 
and accounting rules for the year ended 
31 December 2020 in respect of the acquisition. 

60

“ We continue to monitor the 
integrity of the financial 
statements and other 
announcements as the 
business works to achieve  
its goals”

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Audit and Risk Committee Report continued

In addition, there was a mid-year review of 
financial controls in the US. Key controls have 
been implemented including the appointment 
of a Divisional Financial Controller.

Regular reviews were held with the Company’s 
Auditor, KPMG LLP, without management in 
attendance. In 2021, the Committee welcomed 
Huw Brown as the new lead audit partner. 
The Chair meets with Huw Brown outside of 
the formal Committee meetings as part of 
relationship engagement.

As part of the Committee’s annual review of 
the need for an internal audit function, the 
Committee concluded that, with the growth 
of the business and the corresponding 
complexities, it is appropriate to establish a 
new internal audit function. Management is 
currently in the process of appointing a new 
Internal Audit Manager who will report to me.

The Committee reviews the Group’s risk 
register quarterly, and the Committee believes 
that the Group strategy has the support of 
a management team who understand the 
risk management framework required to 
deliver it. Information about our principal 
risks and uncertainties and our system of 
risk management and internal control can  
be found on pages 39 to 45 and on  
pages 63 and 64.

The Company intends to undertake a tender 
process for audit services and expects this 
process to be completed by Q3 2022. 
Notwithstanding such process, a resolution to 
re-appoint KPMG LLP will be proposed at this 
year’s Annual General Meeting.

Richard Jones
Audit and Risk Committee Chairman

30 March 2022

 › Considering the appointment of external 

auditors and the frequency of re-tendering 
and rotation of the audit.

 › Overseeing the relationship with, and 

the independence and objectivity of, the 
external auditors.

 › Setting policy in relation to the use of the 
external auditors for non-audit services.

 › Advising the Board on the Company’s 

appetite for and tolerance of risk and the 
strategy in relation to risk management 
and reviewing any non-conformances 
with these.

 › Reviewing the Company’s risk 

management and internal control systems 
and their effectiveness.

 › Reviewing the Company’s procedures for 
detecting fraud, bribery and corruption 
and ensuring arrangements are adequate 
for employees to raise concerns.

The role of the Committee
The Audit and Risk Committee assists the 
Board with monitoring and reviewing 
the Company’s financial results and 
other reporting and has oversight of the 
effectiveness of risk management and systems 
of internal control. Its role is to provide 
confidence to shareholders on the integrity 
of our reported financial results and provide 
challenge to the external auditors and 
senior management. 

The framework of duties is set out in its Terms 
of Reference which are available on the 
Company’s website. Each year the Committee 
reviews its own performance and its Terms 
of Reference. 

Duties of the Committee
The duties of the Committee include:

 › Reviewing the management and reporting 

of financial matters including key 
accounting policies.

 › Reviewing the Annual Report and Accounts 
and advising the Board on whether, when 
take as a whole, it is fair, balanced, and 
understandable and provides shareholders 
with the information necessary to assess 
the Company’s performance, business 
model and strategy.

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Additional Information

Audit and Risk Committee Report continued

Members of the Committee have access to the Company Secretary who attends and minutes 
all meetings. To enable the Committee to discharge its duties effectively, the Company 
Secretary is responsible for ensuring the Committee receives high-quality, timely information. 
The Chairman of the Committee works closely with the CFO and the finance department to 
ensure papers for meetings are comprehensive and comprehensible. When appropriate to do 
so, the Committee seeks the support of external advisers and consultants.

The Committee reports to the Board which includes reporting on any matters where it 
considers action or improvement is needed, including recommendation of remedial actions. 
The Chair of the Committee reports to the Board on its proceedings after each meeting on 
all matters, including any reporting issues and on estimates and judgements made in the 
preparation of financial statements. 

Attendance
During the year, the Committee held four scheduled meetings and reported on its activities to 
the Board. 

As at the date of this report, the members of the Audit and Risk Committee, all of whom held 
office throughout the year and to the date of this report unless otherwise stated, are:

Audit and Risk Committee

4 Meetings – 100% attendance

Member

Role

Richard Jones

David Cook

Jo LeCouilliard

Chairman

NED

NED

Status

Independent

Independent

Independent

Attendance

4/4

4/4

4/4

Committee membership and attendance
Appointments to the Committee are made by the Board following any recommendations from 
the Nomination Committee. Only members of the Committee have the right to attend meetings. 
All three members of the Committee have a mix of knowledge and skills gained through their 
experience of business, management practices including risk, the industry sector and have 
recent and relevant financial experience. The CEO, CFO and the Group Head of Finance are 
invited to attend all meetings, while other senior financial managers will attend as appropriate. 

The external auditor also attend the meetings to discuss the planning and conclusions of their 
work and meet with the members of the Audit and Risk Committee without any members of 
the executive team present after each meeting. The Audit and Risk Committee can call for 
information from management and consults with the external auditor directly if required.

Key activities of the Committee

Areas of focus

Financial 
statements 
and narrative 
reporting

Key duties and 
responsibilities

The content and 
integrity of financial 
statements and any 
formal announcements 
relating to financial 
performance, 
including review of the 
significant financial 
reporting judgements 
contained therein.

Activities in the year ended 31 December 2021

 ›

Review of the financial statements and narrative reporting 
in the Annual Report and Accounts for 2020 and 2021 
with reference to the reports being fair, balanced and 
understandable. Included a review of the appropriateness 
of the disclosures considering requirements and guidance 
under IFRS, the AIM Rules for Companies, Companies Act 
2006 requirements, FRC guidance and the QCA Corporate 
Governance Code 2018.

 ›

Review of the preliminary results for the financial years ended 
31 December 2020 and the unaudited half year results to  
30 June 2021.

 › Consideration of reports from the external auditor in respect 
of the Annual Report and Accounts for 2020 and 2021.

Going 
concern 

Matters that have 
informed the Board’s 
assessment of whether 
the Company is a 
going concern.

 › A review of the going concern including methodology, 
assessment in support of the going concern assumption, 
concluding the expectation that the Group has adequate 
resources to continue in operation existence for the 
foreseeable future. 

62

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Audit and Risk Committee Report continued

Areas of focus

Key duties and 
responsibilities

Accounting 
policies and 
standards

Key accounting 
estimates and 
judgements.

Activities in the year ended 31 December 2021

 ›

 ›

In respect of the preparation of the financial statements for 
the year ended 31 December 2021, the Committee reviewed 
key accounting judgements and estimates including a review 
of the group’s weighted average cost of capital (WACC); 
a review of intangible assets including consideration of 
impairment under IAS 36; estimates and judgements in 
respect of going concern, review of alternative performance 
measures, and accounting for the Biogix Inc acquisition. 

The review of the legal and accounting considerations and 
draft disclosures for the financial statements for the year 
ended 2021, including the making of a provision following 
the CMA’s Infringement Decision on 3 February 2022.

 › A review of an assessment under IFRS 15 and the revenue 

recognition in relation to a major cross-border e-commerce 
distribution agreement.

 › A review of the accounting treatment for ERP systems in  

light of IFRS Interpretations Committee decisions on cloud 
computing arrangements.

Risk 
management 
and internal 
controls

Financial and other 
internal controls and 
risk management 
systems, including the 
Group’s Principal Risks 
and Uncertainties.

 › A review of risk management and the Group risk register.

 ›

Review of the Group’s assessment of its control framework, 
including progress in enhancing the control environment.

 › A review of the business and corporate governance statement 

relating to the audit and risk management.

 › A review of the Group’s risk management and internal  

control systems. 

Regulatory and 
compliance risk.

 › Annual review of the need for an internal audit function.
Review of the Company’s Whistleblowing policy  
 ›
and procedures.

Areas of focus

Review of 
external 
auditor

Key duties and 
responsibilities

External auditor’s 
independence and 
objectivity and the 
effectiveness of the 
audit process. 

The policy to control 
engagement of the 
external auditor to 
supply non-audit 
services.

Terms of 
Reference

Reporting to the Board 
on how the Committee 
has discharged its 
responsibilities.

Activities in the year ended 31 December 2021

 › Meetings with the external auditor without management to 

consider any potential areas of concern.

 ›

Review and consideration of the external auditor’s findings 
and recommendations and management’s response from the 
audit of the year ended 31 December 2020 and 2021.
 › Approve the terms of appointment, areas of responsibility  

and duties.

 ›

 ›

 ›

Scope, strategy and fees of the 2021 external audit set out in 
the engagement letter and recommend approval to the Board.

Review of the external auditor’s performance, independence, 
and objectivity.

The Committee reviewed its own Terms of Reference which 
are considered to be satisfactory. The Committee and Board 
were satisfied that the Committee and its members continue 
to operate effectively individually and collectively and had 
discharged all of the duties within its remit.

Risk management and internal controls
The Board has primary responsibility for the Group’s overall approach to risk management 
and systems of internal control and has delegated its oversight to the Committee.

During the year, the Committee has reviewed and reported on the identification, evaluation 
and management of risks facing the business and has considered the effectiveness of 
associated processes and controls to ensure a healthy balance between the risk we 
face and harnessing the opportunities that align with strategy to grow a strong and 
sustainable business.

At least once a year, the Board also reviews risk management and those risks the Board is not 
prepared to take are either avoided or, as far as possible, are mitigated and/or transferred 
to insurers.

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Internal audit function
Every year, the Audit and Risk Committee 
considers the need for an internal audit 
function. This year the Committee has taken a 
decision to establish an internal audit function 
and its activities will be reported in the 2022 
Annual Report.

Whistleblowing
The Company has a Whistleblowing Policy 
and procedures to help with the detection 
and prevention of fraud. Published on the 
Company’s Intranet, the Policy provides all 
employees access to a confidential forum in 
which it is possible to raise concerns about 
potential and perceived improprieties. 
Provided it is appropriate to do so, the 
process is managed by the Company 
Secretary in conjunction with Human 
Resources. The outcomes of any investigations 
carried out in accordance with the Policy is 
reported to the Committee. 

External auditor
Audit process
Each year, the Committee assesses the 
proposed Audit plan for the external 
auditor’s review of the Company’s full-year 
financial statements. This plan sets out the 
scope of the audit, areas of significant 
risk of material misstatement, timetable 
and fees. KPMG formally present their 
findings to the Committee but throughout the 
auditing process there is regular dialogue 
and engagement with management 
with any significant matters or risks 
being communicated. 

Prior to the Board’s approval of the Annual 
Report and Accounts, the Committee reviews 
with the auditor the representations set out 
in the management representation letter and 
reports to the Board. The auditor presents the 
Board with a management representation 
letter which the Committee will have reviewed 
and discussed with the auditor as part of its 
year-end meetings. 

Effectiveness and independence of the 
external auditor
The Committee is responsible for agreeing 
the terms of engagement with the Company’s 
external auditors KPMG. The objectivity 
and independence of the external auditors 
is safeguarded by reviewing the auditors’ 
formal declarations, monitoring relationships 
between key audit staff and the Company, 
and tracking the level of non-audit fees 
payable to the external auditors.

Reappointment of the external auditor
KPMG took up office as the Company’s 
auditor in 2016. The auditor’s appointment 
requires the approval of shareholders at the 
AGM. The Company intends to undertake a 
tender process for audit services and expects 
this process to be completed by Q3 2022. 
Notwithstanding such process, a resolution to 
re-appoint KPMG LLP will be proposed at this 
year’s Annual General Meeting. 

Each year, the Committee reviews the scope 
and fees for the annual audit of the Company.

The responsibilities surrounding risk 
management and internal control systems 
are designed to meet the needs of the size 
and complexity of the business. It takes 
into account the applicable requirements 
of pharmaceutical regulators in the various 
markets in which the business operates as 
well as the legal requirements of being a 
UK company admitted to AIM. Internal 
controls are designed to manage rather than 
eliminate risk and provide reasonable but 
not absolute assurance against material loss 
or misstatement. 

The key components of the current systems of 
internal controls are:

 › Clearly communicating Alliance’s  

values and strategy to ensure these  
are understood and people know  
what is expected.

 › Developing business and financial  
plans that support the strategy.

 › Reviewing policies and procedures to 
ensure these remain fit for purpose.

 › Strengthening controls through enterprise 

resource planning.

 › Regular reporting of actual performance 
relative to goals, budgets and forecasts.

 › Ensuring there is a structure of 

accountability and accountability.

 › Training and monitoring.

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Remuneration Committee Report

Remuneration
Committee 
Report

Chairman’s statement
On behalf of the Remuneration Committee  
(the ‘Committee’), I am pleased to introduce 
this year’s Remuneration Committee Report.

As a company admitted to AIM, we are 
guided by the QCA’s Remuneration Committee 
Guide and, when appropriate to do so, look 
to the UK Corporate Governance Code 2018 
and to investor guidelines for best practice. The 
Committee remains aware of the importance 
placed by investors on remuneration. 

In carrying out its duties, we continue to 
balance our remuneration policy and practices 
with our size and complexity as well as with 
the performance of the business. We promote 
the long-term growth of shareholder value, in 
line with the Group’s strategy, and the need 

to ensure that our people remain motivated 
through fair remuneration strategies. The 
Committee believes that the Company’s current 
remuneration policy encourages and rewards 
the right behaviours and that any risks created 
by its structure are within the appetite of the 
Board. The key activities of the Committee 
during the year included:

 › Reviewing our remuneration policies 

and remuneration levels (both fixed and 
variable) in the context of appropriate AIM 
market comparisons. 

 › Ensuring our policy achieves its objectives 

and continues to attract, retain, and 
motivate a high-quality management team 
to run the Alliance business successfully for 
our shareholders.

65

“ We aim to ensure that 
our remuneration 
arrangements align to 
support implementation of 
the Group’s strategy for the 
medium to long term”

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Remuneration Committee Report continued

 › Considering the context of the potential 

impact of external factors on the 
business and the economy generally, the 
Company’s dividend policy and payments, 
competence, investor sentiment, sector 
performance, affordability, total reward, 
and wider employee view.

 › Reviewing and approving annual bonuses 
against the achievement of targets and 
personal performance.

 › Monitoring and making recommendations 
with respect to the level and structure of 
remuneration for senior management 

 › Assessing the achievement of performance 
conditions and extent of vesting relating to 
share awards which matured in 2021.

 › Approving the grant of share option 
awards under the Company’s share 
incentive plans to the Executive Directors 
and employees.

 › Reviewing the holding requirements under 
the Company’s Share Ownership Policy.

The Committee continues to monitor trends and 
developments in relation to remuneration and 
market practices and corporate governance 
and welcomes views from its shareholders. 
Being committed to and maintaining a healthy 
dialogue with our shareholders helps to ensure 
that our remuneration strategy is understood 
and remains appropriate across all levels of 
the organisation.

I will be attending the AGM on 18 May 
2022 and will be available to answer any 
shareholder questions on the Committee’s 
activities. In the meantime, I would like to thank 
our shareholders for their continued support.

Jo LeCouilliard
Remuneration Committee Chairman

30 March 2022

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The role of the Remuneration Committee
The role of the Remuneration Committee is to ensure there is a formal process for considering 
Executive remuneration. On behalf of the Board, it reviews the pay, benefits, and other 
terms of service of the Executive Directors of the Company and the broad pay strategy with 
respect to other senior executives. The framework of duties is set out in its Terms of Reference 
which are available on the Company’s website. Each year the Committee reviews its own 
performance and its Terms of Reference.

Members of the Committee have access to the Company Secretary who attends and minutes 
all meetings. To enable the Committee to discharge its duties effectively, the Company 
Secretary is responsible for ensuring the Committee receives high-quality, timely information. 
The Chair of the Committee reports to the Board on its proceedings after each meeting on all 
matters within its duties and responsibilities and will make any recommendations to the Board 
it deems appropriate. The Committee will also engage with the Nomination Committee when 
considering, for example, the appointment of Directors or contractual terms on termination.

Committee membership
Appointments to the Committee are made by the Board following any recommendations 
from the Nomination Committee. Only members of the Committee have the right 
to attend meetings. However, where appropriate, the CEO, CFO and the Chief 
People and Infrastructure Officer are also invited to attend certain meetings of the 
Remuneration Committee.

Attendance
During the year, the Committee held a total of six meetings and reported on its activities 
to the Board. As at the date of this report, the membership of the Remuneration Committee 
comprises three Independent Non-executive Directors and their attendance was as follows:

Remuneration Committee

6 Meetings – 100% attendance

Member

Role

Jo LeCouilliard 

Chairman

David Cook

Nigel Clifford*

Kristof Neirynck**

NED

NED

NED

* 

 Nigel Clifford resigned from the Board of Directors on 30 April 2021.

**  Kristof Neirynck joined the Committee on 1 December 2021.

Status

Independent

Independent

Independent

Independent

Attendance

6/6

6/6

2/2

1/1

Activities of the Committee
During the year, matters reviewed and considered by the Remuneration Committee included 
reviewing policies on remuneration, external environment, market comparators, increases 
to annual base salaries, short-term and long-term reward and incentives, and assessing the 
extent to which targets have been achieved under the performance-related bonus scheme. 
When appropriate to do so, the Remuneration Committee seeks the support of external 
advisers and consultants. During the year, the Committee undertook a competitive tender 
process and appointed Ellason LLP as adviser to the Committee. Ellason LLP are members 
of the Remuneration Consultants Group, which sets out guidelines to ensure that any advice 
received is independent. Ellason LLP provides no other services to the Company and the 
Committee is satisfied that the advice received is objective and independent. No Directors or 
senior managers are involved in any decisions as to their own remuneration.

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REMUNERATION POLICY

Remuneration policy tables
As the Company is not a fully listed company, it is not required to produce a formal 
remuneration policy or seek shareholder approval of that policy. However, we set out below 
additional information that the Committee believes will be most useful to shareholders and 
reflects remuneration practices that are appropriate for an AIM company of our size. The 
policy is designed to ensure our Executive Director pay arrangements remain supportive of 
and drive the strategy.

Policy table in respect of Executive remuneration

Element

Policy

Base 
salary

Base salaries are reviewed annually to ensure they remain in line with other pharmaceutical/
healthcare and other AIM companies and reflect the size and scope of the individual’s role. 
Within that frame of reference, the Company aims to be at or near the median level.

Annual base salaries increase in line with the remuneration policy and take effect from May 
each year. The Committee is committed to ensuring that salaries remain competitive relative 
to the AIM 100. Levels are set to attract and retain individuals to lead and drive forwards the 
agreed strategy for the Company.

Pension 
and other 
benefits

Executive Directors can participate in the Company’s defined contribution pension scheme. In 
line with all employees, only their base salaries are pensionable. The Company contributes twice 
the amount contributed by the employee up to a maximum of 10%. When appropriate to do 
so, Executive Directors may take benefits as a salary cash supplement (which will ordinarily be 
reduced to take account of the employer National Insurance Contributions).

Other benefits in kind include life assurance, healthcare and the provision of a cash allowance in 
lieu of a company car.

Element

Policy

Annual 
bonus

The delivery of the Group’s in-year, short-term corporate goals is incentivised by offering a  
cash-settled bonus (‘Annual Bonus’) linked to two factors:

 ›

the achievement of budgeted levels of underlying profit before tax, which is the key metric the 
Board considers in monitoring corporate performance; and

 ›

personal performance of each Executive.

As part of this incentive strategy Executive Directors are eligible to participate in the all-
employee Annual Bonus scheme. The level of that bonus is determined by first assessing 
whether the threshold level of financial performance has been achieved by the business and, 
once this has been achieved, applying a further multiplier which is determined by assessment 
of the Executive’s personal performance for the relevant year.

The financial targets are set at the start of each financial year – the targets are determined with the 
approval of the Remuneration Committee to ensure they incentivise the Executives and align with 
delivery of the Group’s strategy.

Personal performance is measured on various factors including delivery of pre-set personal targets.

Based on a combination of financial and personal performance, the Annual Bonus that each of the 
Executives is able to earn is as follows:

Chief Executive Officer  
A bonus of 50% of base salary is payable for on-target financial performance, increasing on a 
sliding scale up to a maximum of 100% of base salary.

The bonus payable can be further increased by applying a personal performance multiplier.  
The maximum personal performance multiplier is 1.5x (i.e. up to an additional 50% of salary).

The CEO’s potential maximum Annual Bonus opportunity is therefore 150% of base salary.

Chief Financial Officer 
A bonus of 40% of base salary is payable for on-target financial performance, increasing on a 
sliding scale up to a maximum of 80% of base salary.

The bonus can be further increased by applying a personal performance multiplier. The 
maximum personal performance-related multiplier is 1.5x (up to an additional 40% of salary).

The CFO’s potential maximum Annual Bonus opportunity is therefore 120% of base salary.

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REMUNERATION POLICY CONTINUED

Element

Policy

Policy table in respect of Non-executive remuneration

Remuneration/ 
Benefit

Application

Fees

Non-executive Directors of the Company receive a basic fee for the services provided to the 
Company. These are reviewed by the Company from time to time to ensure levels remain in line 
with comparable companies. There are no performance measures in relation to fees paid to  
Non-executive Directors.

The Non-executive Directors do not receive an additional allowance for chairing one or more of 
the Committees of the Board.

Share 
incentive 
schemes

The Company operates two share incentive schemes to encourage a culture of long-term growth 
and performance that aligns with share ownership. Executive Directors can participate in both 
the market value Company Share Option Plan (CSOP), and a nil-cost Long-Term Incentive 
Plan (LTIP).

Any awards granted to the Executive Directors are subject to performance metrics which are 
reviewed regularly by the Committee, and the level of award is reviewed annually to ensure that 
the aggregate remuneration remains competitive.

Performance targets for Directors’ awards granted under the LTIP and CSOP continue to be 
based on Earnings Per Share (EPS) and Total Shareholder Return (TSR) related targets, assessed 
over a three-year performance period.

The maximum total market value of shares over which awards may be granted under the LTIP 
to any participant during any financial year is 100% of the participant’s salary. However, in 
exceptional circumstances, the Committee may, at its absolute discretion, grant a higher amount. 
The maximum market value of shares under the approved part of the CSOP shall not exceed 
£30,000. There is no limit on the market value of shares when granting unapproved share 
option awards.

Further information about the Company’s share incentive plans is set out on page 81.

Share 
ownership

To align Directors and Senior Management’s interests with our shareholders, the Company 
operates a Share Ownership Policy.

When exercising share options relevant employees are required to build a qualifying interest 
in shares or vested options capable of exercise that is equal to a percentage of their base 
salary at the prevailing time. Ordinary shares are valued at their market value at the time of 
any calculation carried out to determine whether a qualifying interest has been established or 
needs to be increased. The CEO is required to build a qualifying interest equal to 200% of his 
base salary, while the CFO is required to build an interest equal to 150% of his salary. Further 
information can be found on page 74 of this report.

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DIRECTORS’ REMUNERATION

The aggregate remuneration payable to the Directors in respect of the period was as follows:

Peter Butterfield

Andrew Franklin

Nigel Clifford1

David Cook

Richard Jones

Jo LeCouilliard

Kristof Neirynck2

Salary or fees

Other

Pension

Bonus

Total remuneration, 
excluding share options

Exercised share  
option gains

Total remuneration, including 
share options

2021

2020

2021

2020

2021

2020

2021

2020

2021

2020

2021

2020

2021

2020

335,500

311,667

12,377

12,328

28,998

27,389

238,889

206,250

615,764

557,634

363,146

54,400

978,910

612,034

226,667

210,000

11,922

8,590

22,667

20,636

155,940

110,000

417,296

349,226

15,000

82,667

45,750

44,389

78,488

44,389

45,750

42,723

3,844

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

15,000

82,667

45,750

44,389

78,488

44,389

45,750

42,723

3,844

–

–

–

–

–

–

–

–

–

–

–

–

–

417,296

349,226

15,000

82,667

45,750

44,389

78,488

44,389

45,750

42,723

3,844

–

755,178

731,656

24,299

20,918

51,665

48,025

394,829

316,250 1,225,971

1,116,849

363,146

54,400 1,589,217

1,172,249

1  Nigel Clifford retired from the Board as a Non-executive Director on 30 April 2021.

2  Kristof Neirynck joined the Board as an independent Non-executive Director on 1 December 2021.

No Director received any remuneration from a third party in respect of their service as a 
Director of the Company.

Base salary
Base salaries for the CEO and CFO were increased in line with the wider workforce during the 
year from £330,000 to £338,250 for the CEO and from £220,000 to £230,000 for the CFO. 
These increases took effect on 1 May 2021.

Pension and benefits
Both the CEO and CFO received an employer pension contribution of twice the amount 
contributed by the Director up to a maximum of 10% of salary.

The column headed ‘Other’ in the table above shows the value of benefits provided to each 
Executive Director, including a cash allowance in lieu of a company car and healthcare. Only 
the Executive Directors accrue retirement benefits, and both of whom did so through defined 
contribution (money purchase) schemes. The Company does not operate a defined benefit 
scheme. No Director or former Director received any benefits from a retirement benefits 
scheme that were not otherwise available to all members of the scheme.

Annual bonus
The Committee reviewed the achievement of actual underlying profit before tax (PBT) against 
budgeted levels of underlying PBT — the key metric for monitoring corporate performance. 
In addition, the Committee considered the personal performance of the Executive Directors 
as measured against various factors including pre-set personal objectives. For the Executive 
Directors this resulted in the following payments:

Peter Butterfield

Andrew Franklin

2021
£

238,889

155,940

2020
£

206,250

110,000

2021
% salary

71

68

2020
% salary

62.5

50

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DIRECTORS’ REMUNERATION CONTINUED

Non-executive Directors’ fees
An increase to Non-executive Directors’ fees was approved during the year and took effect 
on 1 May 2021. The annual fee paid to David Cook is £84,000. Jo LeCouilliard, Kristof 
Neirynck and Richard Jones each receive a fee of £46,125 per annum. Non-executive 
Directors do not receive an additional allowance for chairing one or more of the Committees 
of the Board.

Share incentive awards
The Company operates two share incentive schemes under which share options are granted 
to Executive Directors and senior management. More details on our share plans can be found 
in the Directors’ Report on page 81.

Awards under the Alliance Company Share Option Plan 2015 (CSOP)
During the year, the Committee approved the award of market value share options to the 
Executive Directors and Senior Leadership Team (‘SLT’). The quantum of award is one share 
for every £2 of base salary and, where appropriate, may attract HMRC tax advantages.

On 29 September 2021, the Company granted Peter Butterfield 29,182 approved and 
139,943 unapproved share options under the CSOP. On the same date, the Company 
granted Andrew Franklin 115,000 unapproved share options under the same plan. These 
share options were all granted with an exercise price of 102.8p per share (being the closing 
mid-market price of one 1p Ordinary share in the Company at close of trading on 28 
September 2021). Based on the exercise price, the value of the awards as at the date of grant 
was equal to £173,860 for the CEO and £118,220 for the CFO. These awards will vest on 
the third anniversary from the date of grant, 29 September 2024, subject to meeting the EPS 
and TSR performance targets as set out on page 72.

Awards under the Alliance Long-Term Incentive Plan 2019 (LTIP)
The Committee also approved awards granted under the Company’s LTIP in the form of nil-
cost options. These were granted on 29 September 2021 with a face value of 55% of base 
salary to Peter Butterfield, equal to £186,037 (180,970 option awards); and 45% of base 
salary to Andrew Franklin, equal to £103,500 (100,681 option awards). The strike price used 
to calculate the quantum of awards was 102.8p per share (being the closing mid-market 
price of one 1p Ordinary share in the Company at close of trading on 28 September 2021). 
These awards will vest on the third anniversary from the date of grant, 29 September 2024, 
subject to meeting the EPS and TSR performance targets on the following page.

Malus and clawback
All awards under the LTIP are subject to standard malus and clawback provisions which allow 
the Company, in certain circumstances, to either (i) terminate outstanding options, or (ii) seek 
repayment of after tax value of options which have been exercised by an Executive which 
has been dismissed as a result of a set of prescribed irregularities including the discovery 
of material misstatement of results of the Company or Group; or a serious breach of the 
Company’s code of ethics has arisen; or a serious regulatory, or health and safety issue 
has occurred.

Performance conditions
All options granted to Executive Directors before 2019 will only vest if targets for growth in 
the Company’s underlying diluted Earnings Per Share (EPS) are met over a period of three 
years. EPS is an important metric which provides a strong incentive to drive the Group’s 
business over that longer-term period and to mitigate downside risks that could affect the 
Group’s profitability. Reputation risks could reasonably be expected to affect the share price, 
so the Executive is further incentivised to mitigate these exposures, if they wish to maximise the 
potential value of their options.

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DIRECTORS’ REMUNERATION CONTINUED

In 2019, the Committee reviewed performance targets as part of the introduction of the LTIP 
and introduced a second measure, in addition to EPS, based on Total Shareholder Return 
(TSR). As such, all options granted in 2021 to Executives under the CSOP and LTIP are subject 
to EPS and TSR performance conditions. 50% of the awards are subject to EPS and 50% are 
subject to TSR as set out below:

Awards vesting during the year
On 5 October 2021, market value share options made in 2018 under the CSOP to Peter 
Butterfield and Andrew Franklin vested 100% based on the achievement of the EPS target for 
the financial year ending 31 December 2020 of 4.58p (being RPI+2% per annum over the 
three year performance period).

EPS Compound Annual Growth Rate  
over the performance period

< 5% CAGR

5% – 10% CAGR

> 10% CAGR

% of award that vests (of 50%)

0%

Calculated on a straight-line basis between 50% and 100%

100%

CAGR: means compound annual growth rate.

EPS: means the underlying diluted earnings per share as presented in the Company’s published Annual Reports.

EPS Compound Annual Growth Rate: means the percentage of increase in the EPS of the Company calculated by reference to the difference between 
(i) the EPS as presented in the published Annual Report for the financial year ending 31 December 2020, to (ii) the EPS as presented in the published Annual 
Report for the financial year ending 31 December 2023.

EPS Performance Period: the period from 31 December 2020 to 31 December 2023 (inclusive).

TSR against the FTSE Small Cap Index (ex-Trusts) over the performance period

% of award that vests (of 50%)

Less than the Index

Equal to the Index

0%

50%

Between the Index but less than 15% out-performance of the Index  
on a cumulative basis over the TSR performance period

Calculated on a straight-line  
basis between 50% and 100%

Equal to or greater than 15% out-performance of the Index on a cumulative 
basis over the TSR performance period

100%

On 27 October 2021, market value share options made in 2016 under the CSOP to Peter 
Butterfield and Andrew Franklin vested 100% based on the achievement of an EPS target for 
the financial year ending 31 December 2020 of 4.52p (being RPI+2% p.a. over the five year 
performance period).

Details of the number of shares vesting and the relevant exercise prices for these option 
awards are set out in the table on page 73.

120

115

110

105

100

95

90

85

80

Index: means the FTSE Small Cap Index, excluding investments trusts as determined by the Company’s nominated adviser.

Jan - 21

Mar - 21

May - 21

Jul - 21

Sep - 21

Nov - 21

Dec - 21

TSR: means total shareholder return calculated by reference to the Company’s share price appreciation plus all dividend per share paid (based on ex 
dividend date) during the TSR Performance Period, and as determined by the Company’s Nominated Adviser at the end of the TSR Performance Period.

TSR Performance Period: the period starting on the Grant Date and ending on the third anniversary of the Grant Date.

  Alliance

  FTSE Small Cap (ex. Investment Trusts)

  FTSE AIM 100

The closing mid-market price of Ordinary shares on 31 December 2021 (being the last 
dealing day in the calendar year) was 108.8p and the range during the year was from  
82.0p to 110.0p.

72

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Strategic Report

Governance

Financial Statements

Additional Information

Remuneration Committee Report continued

DIRECTORS’ REMUNERATION CONTINUED

Share incentive awards
Executive Directors hold options through 
the Company’s share option and long-
term incentive plans. Details of options 
held under the Company’s employee 
share schemes by the Directors as at 
31 December 2021 and who served 
during the year are as shown opposite. 
Shares are retained as required in order 
to comply with the Company’s Share 
Ownership Policy for which details are 
provided on page 74.

On 21 April 2021, Peter Butterfield 
exercised 205,000 options over Ordinary 
shares of 1p each granted to him by the 
Company under the CSOP in 2017. The 
exercise price was 53.0p per share. 
93,000 shares were then subsequently 
sold at a market price of 95.4p per share. 

On 19 November 2021, Peter Butterfield 
exercised 500,000 options over Ordinary 
shares of 1p each granted to him by 
the Company under the CSOP in 2016. 
The exercise price was 47.5p per share. 
269,417 shares were then subsequently 
sold at a market price of 102.5p per share.

Peter Butterfield

Type of award

Date of grant

Exercise price 
(p) 

Performance 
condition

No. of  
options granted

Vested

Exercised

Lapsed

CSOP Unapproved
CSOP Unapproved
CSOP Approved

CSOP Unapproved
CSOP Unapproved
LTIP
CSOP Unapproved
LTIP
CSOP Unapproved
CSOP Approved
LTIP

27-Oct-16
15-Sep-17
15-Sep-17

05-Oct-18
05-Dec-19
05-Dec-19
23-Sep-20
23-Sep-20
29-Sep-21
29-Sep-21
29-Sep-21

Andrew Franklin

47.50
53.00
53.00

81.60
76.90
Nil
73.70
Nil
102.80
102.80
Nil

EPS
EPS
EPS

EPS
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR

1,000,000
148,397
56,603

1,250,000
137,500
196,684
165,000
246,269
139,943
29,182
180,970
3,550,548

1,000,000
148,397
56,603

1,250,000
–
–
–
–
–
–
–
2,455,000

500,000
148,397
56,603

–
–
–
–
–
–
–
–
705,000

–
–
–

–
–
–
–
–
–
–
–

Type of award

Date of grant

Exercise price 
(p) 

Performance 
condition

No. of 
 options granted

Vested

Exercised

Lapsed

CSOP Unapproved
CSOP Unapproved
CSOP Unapproved

CSOP Unapproved
CSOP Unapproved
CSOP Approved
CSOP Unapproved
LTIP
CSOP Unapproved
LTIP
CSOP Unapproved
LTIP

04-Dec-15
27-Oct-16
27-Oct-16

15-Sep-17
05-Oct-18
05-Dec-19
05-Dec-19
05-Dec-19
23-Sep-20
23-Sep-20
29-Sep-21
29-Sep-21

46.75
47.50
47.50

53.00
81.60
76.90
76.90
Nil
73.70
Nil
102.80
Nil

No
EPS
EPS

EPS
EPS
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR
EPS & TSR

1,935,829
155,000
400,000

170,000
178,000
39,011
55,989
111,183
110,000
134,328
115,000
100,681
3,505,021

1,935,829
155,000
400,000

170,000
178,000
–
–
–
–
–
–
–
2,838,829

1,435,829
–
–

–
–
–
–
–
–
–
–
–
1,435,829

–
–
–

–
–
–
–
–
–
–
–
–

Andrew Franklin did not exercise any share options during the year.

Number of 
options capable 
of exercise

Exercisable 
from

Exercisable 
 to

500,000
–
–

27-Oct-21
15-Sep-20
15-Sep-20

27-Oct-26
15-Sep-27
15-Sep-27

1,250,000

05-Oct-21

05-Oct-28
– 05-Dec-22 05-Dec-29
– 05-Dec-22 05-Dec-23
23-Sep-24
– 23-Sep-23
23-Sep-24
– 23-Sep-23
29-Sep-31
– 29-Sep-24
29-Sep-31
– 29-Sep-24
29-Sep-25
– 29-Sep-24

1,750,000

Number of 
options capable 
of exercise

Exercisable 
from

Exercisable 
to

500,000
155,000
400,000

04-Dec-18 04-Dec-25
27-Oct-26
27-Oct-19
27-Oct-26
27-Oct-21

170,000
178,000

15-Sep-20
05-Oct-21

15-Sep-27
05-Oct-28
– 05-Dec-22 05-Dec-29
– 05-Dec-22 05-Dec-29
– 05-Dec-22 05-Dec-23
23-Sep-24
– 23-Sep-23
23-Sep-24
– 23-Sep-23
29-Sep-31
– 29-Sep-24
29-Sep-25
– 29-Sep-24

1,403,000

73

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Strategic Report

Governance

Financial Statements

Additional Information

Remuneration Committee Report continued

DIRECTORS’ REMUNERATION CONTINUED

Directors’ interests and shareholdings
Share ownership policy
The Company operates a share ownership policy under which the Executive Directors and 
certain other employees are required when exercising options to acquire and maintain an 
interest in Alliance Pharma shares up to a percentage of base salary. The policy requires 
Executive Directors, when they exercise options, to retain shares in the Company with a value 
equal to 50% of the net gain (post costs and settlement of tax liabilities) until such time as the 
required level of shareholding is achieved. 

Once an Executive Director has built a stake in the Company equal to the required levels, 
they are free to exercise without having to retain shares. Interests may also be maintained as 
a result of a Director acquiring Ordinary shares in the open market. The Company Secretary 
maintains a record of individual required levels and qualifying interests based on information 
provided by an individual subject to this policy and reports periodically to the Remuneration 
Committee regarding compliance. Pursuant to the policy, 50% of the value of any vested but 
unexercised awards count towards the holding requirements. Ordinary shares are valued at 
their market value at the time of any calculation carried out using the previous day’s closing 
middle market quotation.

From 1 April 2021, the holding requirements under the share ownership policy increased from 
100% to 200% of base salary for the CEO and from 100% to the 150% of base salary for  
the CFO.

As at 21 March 2022, the Executive Directors hold the following interests in Ordinary shares 
of the Company:

Director

Percentage  
of salary

2021  

Base salary Shareholding

Vested but 
unexercised 
awards

Value of 
holdings*

% achieved

Peter Butterfield CEO

200%

£338,250

442,104

1,750,000

£838,504

Andrew Franklin CFO

150%

£230,000

128,384

1,403,000

£558,129

248%

243%

* 

 At the closing market price on 21 March 2022: 111.4p.

The following table shows the interests of the Directors (and their spouses and minor children) 
in the shares of the Company.

Director

Beneficial

Non-beneficial

Total

Beneficial

Non-beneficial

Total

At 31 December 2020

At 31 December 2021

Peter Butterfield

Andrew Franklin

David Cook

Richard Jones

Jo LeCouilliard

Kristof Neirynck

412,461

128,384

234,129

15,000

–

–

–

–

–

–

–

–

412,461

442,104

128,384

128,384

234,129

234,129

15,000

15,000

– 

–

–

–

–

–

–

–

–

–

442,104

128,384

234,129

15,000

–

–

74

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Remuneration Committee Report continued

DIRECTORS’ REMUNERATION CONTINUED

Directors’ service contracts
All Executive Directors are employed under 12-month rolling service contracts. The services of all 
Executive Directors may be terminated (i) by the Company or individual giving 12 months’ notice 
or (ii) immediately, in the event that the Director is not re-elected by shareholders at an AGM.

Executive Director

Peter Butterfield

Andrew Franklin

Chief 
Executive

Chief 
Financial 
Officer

Date of  
appointment

Date of  
current contract Unexpired term

Notice period 
(Company)

Notice period  
(Director)

22/02/2010 05/08/2010

Rolling 12 months 12 months

12 months

28/09/2015 25/06/2015

Rolling 12 months 12 months

12 months

The Non-executive Directors are employed under letters of engagement which may be 
terminated by the Company by (i) giving the appropriate notice, or (ii) immediately, in the 
event that the Director is not re-elected by shareholders at an AGM.

Non-executive 
Director

First date of  
appointment

Current term

Unexpired term

David Cook

Chair & Independent NED 01/04/2014

Jo LeCouilliard

Independent NED

Richard Jones

Independent NED

01/01/2019

01/01/2019

Kristof Neirynck

Independent NED

01/12/2021

4 years

5 years

5 years

5 years

13 Months

22 Months

22 Months

57 Months

The Executive Directors’ service contracts and Chairman and Non-executive Directors’ letters 
of appointment are available for inspection by shareholders at the Company’s registered 
office or by emailing the Company Secretary at Company.Secretary@AlliancePharma.co.uk. 

75

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Financial Statements

Additional Information

ESG Committee Report

ESG
Committee 
Report

“ Driving ESG and the 
sustainability agenda is  
a real positive step 
benefiting all stakeholders 
across our business and  
its operations”

Chairman’s statement
I am pleased to be introducing the first report 
from the ESG Committee (the ‘Committee’).

This Committee was newly formed in 2021 and 
during the last year it has been busy getting to 
grips with issues associated with our approach 
to sustainability, environmental considerations 
including climate change, government policies, 
metrics, reporting requirements, and investor 
and other stakeholder needs all of whom are 
engaging with this much-needed agenda.

In this report we set out the Committee’s 
responsibilities and report on the activities of 
the Committee during the year. The business 
sees this as a much needed and positive 
step forward and there has been good 
engagement with our various stakeholders. 

In particular, the Committee would like 
to thank our employees who took part 
in the workshops which preceded the 
creation of the Sustainability Forum 
and to those shareholders who have 
also worked with us to help us better 
understand responsible investing. 

The Committee looks forward to building  
on all the hard work being done.

David Cook
ESG Committee Chairman

30 March 2022

76

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Financial Statements

Additional Information

ESG Committee Report continued

The role of the Committee
The ESG Committee’s primary role is to 
review the overarching ESG vision for the 
Company and ensure that the priorities 
are anchored and an integral part of the 
Company’s overall strategy.

Duties of the Committee
The duties of the Committee include:

 › To ensure that the views of stakeholder 

groups on ESG matters are solicited and 
understood to inform the Company’s  
long-term strategic decisions.

 › To identify the relevant ESG priorities that 

most significantly impact the Company and 
its stakeholders, its reputation and public 
interest role.

 › To assist in defining and executing the 
Company’s strategy and, in so doing, 
agree the annual plan and targets relating 
to ESG matters.

 › To review the Company’s performance 

against its annual plan and ESG targets, 
initiatives and commitments.

 › To guide the Company’s ESG 

communication strategy.

 › To ensure that ESG priorities are reflected  

in the Company’s culture through its 
purpose, vision, values and behaviours  
as well as its supplier code of conduct.

Committee membership
All Board members currently sit in the Committee and have the right to attend meetings. 

The Committee works closely with the SLT and meetings are also attended by the Corporate 
Sustainability Lead. Others are invited to attend as appropriate to support the Committee 
with discussions.

Committee membership changes
Nigel Clifford stepped down from the Committee on the 30 April 2021. With effect from 
1 December, Kristof Neirynck was appointed a member of the ESG Committee.

Attendance
During the year, the Committee held three scheduled meetings and reported on its activities to 
the Board.

ESG Committee

3 Meetings – 100% attendance

Member

Role

Activities of the Committee
An overview of our approach and 
sustainability framework can be found  
on page 25.

Activities
 › Reviewed 2021 and 2022 objectives and 
sustainability framework and initiatives.

 › Received investor presentations to 

understand ESG investor perspectives. 

 › Reviewed feedback from one to one 

meetings held with investors to understand 
their objectives.

 › Reviewed the mapping of Alliance’s 

sustainability disclosures and accounting 
metrics to SASB.

 › Reviewed the Company’s ratings with 

Status

Attendance

MSCI and Sustainalytics.

David Cook

Peter Butterfield

Andrew Franklin

Jo LeCouilliard

Richard Jones

Kristof Neirynck

Chairman

Independent

CEO

CFO

NED

NED

NED

–

–

Independent

Independent

Independent

3/3

3/3

3/3

3/3

3/3

3/3

 › Appointed energy consultancy firm to 
help shape the medium-term ambition 
particularly in areas of TCFD and Scope 3 
emissions, supply chain management and 
development of key metrics.

 › Oversaw the Company’s environmental 

strategy, carbon action plan and 
sustainable packaging strategy.

 ›

Liaised with Remuneration Committee to 
develop ESG link to remuneration strategy.

 › Reviewed the Acting Responsibly section 

on the corporate website.

77

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Financial Statements

Additional Information

Task Force on Climate-related Financial Disclosures (TCFD)

The purpose of the TCFD recommendations is to provide 
a foundation to improve investors’ and others’ ability to 
appropriately assess and price climate-related risks and 
opportunities. The recommended disclosures are structured 
around four thematic areas that represent core areas of how 
organisations operate: governance, strategy, risk management, 
and metrics and targets. 

We are still in the early stages of evaluating the impact of 
climate change on our business and strategy. As part of our 
2021 reporting, we are therefore making partial disclosures, 
setting out our approach to climate-related issues as they 
relate to governance, strategy and risk management, together 
with those metrics which we are currently able to provide. 

We are looking to undertake the scenario analysis required 
to enable us to provide more extensive disclosures in line with 
TCFD recommendations in 2022, as we progress our wider 
environmental sustainability strategy. This will form part of our 
reporting for the year ended 31 December 2022.

Recommendation

Governance

Disclose the organisation’s governance around climate-related risks  
and opportunities.

Response

Further information

The ESG Committee is responsible for setting the Group’s overarching 
sustainability strategy, including its environmental strategy, and for identifying 
relevant ESG priorities that most significantly impact the Group, including those 
relating to climate change.

Governance – ESG Committee Report – page 76

a) Describe the Board’s oversight of climate-related risks and opportunities.

b)  Describe management’s role in assessing and managing climate-related 

The SLT, supported by the Corporate Sustainability Lead, is responsible for 
operationalising this strategy.

risks and opportunities.

Strategy

Disclose the actual and potential impacts of climate-related risks and 
opportunities on the organisation’s businesses, strategy, and financial  
planning where such information is material.

a)  Describe the climate-related risks and opportunities the organisation  

has identified over the short, medium, and long term.

b)  Describe the impact of climate-related risks and opportunities on the 

organisation’s businesses, strategy, and financial planning.

c)  Describe the resilience of the organisation’s strategy, taking into 

consideration different climate-related scenarios, including a 2°C  
or lower scenario.

The actual and potential impacts of climate-related risks and opportunities 
on the Group’s business, strategy and financial planning have yet to be fully 
quantified. We are therefore unable to determine the extent to which these 
are likely to be material. Given the nature of our business and our operating 
model, whilst there are likely to be some financial and operational impacts, at 
this stage we have yet to determine the extent to which these may be material. 

We expect to complete the scenario analysis required to enable us to make a 
proper assessment during 2022.

Environmental Strategy – page 33

78

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Governance

Financial Statements

Additional Information

Task Force on Climate-related Financial Disclosures (TCFD) continued

Recommendation

Risk Management

Disclose how the organisation identifies, assesses, and manages climate-
related risks.

a)  Describe the organisation’s processes for identifying and assessing  

climate-related risks.

b)  Describe the organisation’s processes for managing climate-related risks.

c)  Describe how processes for identifying, assessing, and managing  
climate-related risks are integrated into the organisation’s overall  
risk management.

Metrics & Targets

Disclose the metrics and targets used to assess and manage relevant climate-
related risks and opportunities where such information is material.

a)  Disclose the metrics used by the organisation to assess climate-related risks 
and opportunities in line with its strategy and risk management process.

b)  Disclose Scope 1, Scope 2, and, if appropriate, Scope 3 greenhouse gas 

(GHG) emissions, and the related risks.

c)  Describe the targets used by the organisation to manage climate-related 

risks and opportunities and performance against targets.

Response

Further information

Climate change has been identified as an emerging risk, on the basis that we 
do not currently have sufficient clarity around it to be able to assess its likely 
impact, and the likelihood of this impact occurring.

The risk has been included on the Group risk register and is being managed as 
part of the Group’s wider risk management framework, under the oversight of 
the Board with the support of the Audit and Risk Committee

Principal Risks and Uncertainties – pages 39–45

Additional information on metrics and targets used to assess and manage 
relevant climate-related risks, to the extent that they are material, will be 
provided as part of our 2022 reporting once we have completed the required 
scenario analysis.

Environmental Strategy – page 33 

Our Scope 1 & 2 GHG emissions for our UK operations for 2021 are included 
as part of our Streamlined Energy and Carbon Reporting (SECR)

SECR – page 83 

In 2021, we quantified our Scope 3 GHG emissions for 2020. This led to 
‘Environmental impacts – supply chain and logistics’ being included as one 
of the eight Areas of Focus within our Sustainability Framework. We intend to 
publish emissions reductions targets in late 2022 for Scopes 1 & 2 and are 
aiming to set Scope 3 targets in 2023. 

Sustainability Overview – pages 25–27

Sustainability Performance – page 28–32

79

Alliance Pharma plc – Annual Report and Accounts 2021 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Directors' Report

Scope of this report
The Directors present their Annual Report, 
together with the audited financial statements 
of the Company and the Group, for the year 
ended 31 December 2021. 

The Directors’ Report required under the 
Companies Act 2006 includes and comprises 
the Directors’ biographies on pages 48 and 
49, the Governance statement on pages 50 
to 55, the Remuneration Committee Report on 
pages 65 to 75 and the Strategic Report on 
pages 06 to 45. 

As permitted under the Companies Act 2006, 
certain matters which would otherwise need 
to be included in this Directors’ Report have 
instead been discussed in the Strategic Report 
on pages 06 to 45. These matters include 
any important post-balance sheet events, 
the likely future developments in the business 
of the Company and its subsidiaries, the 
activities of the Company and its subsidiaries 
in the field of research and development. 

Principal activities
The principal activity of the Company is to act 
as a holding company. The principal activity 
of the Group is the acquisition, marketing 
and distribution of consumer healthcare 
and pharmaceutical products. 

Branches
A list of the Group’s subsidiaries and 
associated undertakings can be found on 
pages 121 and 122 under note 13 to the 
financial statements. There are no branches 
of the Company outside the UK. Alliance 
Pharmaceuticals GmbH, a company within 
the Alliance Group, has a Swiss branch 
which operates under the name Alliance 
Pharmaceuticals GmbH Düsseldorf, 
Zweigniederlassung Uster.

Directors
Names and biographical details of the 
Directors of the Company at the date of this 
report are shown on pages 48 and 49. The 
rules setting out the powers of Directors, their 
appointment and replacement is set out in the 
Company’s Articles of Association. Further 
information on the process can be found on 
page 59 of the Nomination Committee Report. 

Details of Executive Directors’ service contracts 
and letters of appointment for Non-executive 
Directors can be found in the Remuneration 
Report on page 75. All Directors put 
themselves forward for annual re-election at 
the Company’s Annual General Meeting. 

Directors’ indemnities
The Company’s Articles of Association contain 
provision for Directors to be indemnified 
(including the funding of defence costs) to the 
extent permitted by the Companies Act 2006.  

This indemnity would only be available if 
judgement was given in the individual’s favour, 
or he or she was acquitted, or relief under 
the Companies Act 2006 was granted by 
the court. There were no qualifying pension 
scheme indemnity provisions in force during 
the year.

Share capital and shareholders’ rights
The Company’s issued share capital as at the 
21 March 2022 is 538,658,812 Ordinary 
shares of 1p each. Each Ordinary share carries 
one vote at general meetings of the Company. 
There are no restrictions on the transfer of 
Ordinary shares other than restrictions, which 
may from time to time be imposed by law. The 
Company is not aware of any agreements 
between shareholders that may restrict transfer 
of securities or voting rights.

The Company has no shareholder authority  
to acquire its own shares. 

Dividends
The Board declared an interim dividend in 
respect of the year ending 2021 of 0.563p 
per share (2020: 0.536p) which was paid 
on 7 January 2022. The Directors are 
recommending a final dividend of 1.128p 
per share (2020: 1.074p) which, subject to 
shareholders’ approval at the AGM, will be 
paid on 7 July 2022 to shareholders on the 
register at close of business on 10 June 2022. 

The total dividend paid and proposed in 
respect of the year ended 31 December 2021 
is therefore 1.691p per share (2020: 1.610p).

Substantial shareholdings
As at the 21 March 2022, as required 
under AIM and certain disclosure rules, the 
Company has been notified of the major 
shareholdings in the table below. Both the 
number of shares held, and the percentage 
holding are stated as at the latest date of 
notification to the Company. Details of all 
major shareholdings can also be found in the 
Investor section of the Company’s website. 

Shareholder

Number of 
shares held

Percentage  
of issued  
share capital

Fidelity Mgt & Research

53,913,307

10.01%

Slater Investment

49,692,096

Van Lanschot Kempen

42,254,750

Blackrock Inc.

Investec Group

Rathbone plc

34,648,461

24,825,908

20,626,281

Polar Capital Holdings

19,096,921

Royal Bank of Canada

16,197,254

9.23%

7.84%

6.43%

4.61%

3.83%

3.55%

3.01%

80

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Strategic Report

Governance

Financial Statements

Additional Information

Directors' Report continued

Company share incentive plans
The Company operates two incentive  
share plans.

The Alliance Company Share Option 
Plan 2015 (CSOP)
For many years, the Company has operated a 
CSOP under which all employees are eligible 
to receive awards in the form of market value 
options. At the discretion of the Committee, 
awards are typically granted subject to a 
three-year vesting period and following 
maturity, participants have a seven-year 
period in which to exercise their options. 

Options awarded are based on one share for 
every £2 of salary and where appropriate 
may attract HMRC tax advantages. Employees 
based outside of the UK will receive non-tax 
advantaged share option awards and, where 
this is not possible, the Committee considers 
awards in the form of share appreciation rights. 

All awards granted to Executive Directors 
and Senior Management are subject to 
performance conditions. These are explained 
in the Remuneration Committee Report on 
pages 71 and 72.

The Alliance Long-Term Incentive Plan 
2019 (LTIP)
In 2019, the Company introduced the  
LTIP which forms part of the remuneration 
strategy for the Executive Directors and 
members of the Senior Leadership Team. 
Awards are granted in the form of nil-cost 
share options based on a percentage of base 
salary. All awards granted under the LTIP 
are subject to performance conditions and 
malus and clawback provisions. Subject to 
achieving the performance conditions set by 
the Committee, such awards will vest three 
years from the date of grant and participants 
will have 12 months in which to exercise any 
vested award.

Details in relation to awards granted to the 
Company’s Executive Directors are contained 
in the Remuneration Report on page 73.

Employee Benefit Trust (EBT/Trust) and 
management of dilution
The Company manages dilution rates within 
the standard guidelines. In 2017 the Group 
established the Alliance Pharma Employee 
Benefit Trust to facilitate the acquisition of 
Ordinary shares in the Company for the 
purpose of satisfying awards granted under 
share option schemes. The Group has  
been operating the Trust to help manage 
dilution limits in line with good practice.  

The Trust is administered by an independent 
Trustee who operates the Trust independently 
of the Group. The EBT is a discretionary 
trust, the sole beneficiaries being employees 
(including Executive Directors) of the Group 
who have received applicable awards. 

The Trustees must act in the best interests of 
the beneficiaries as a whole and will exercise 
their discretion in deciding whether or not to 
act on any recommendations proposed by 
the Company. Any assets held by the Trust 
would be consolidated into the Group’s 
financial statements.

The Company may grant awards on the 
basis that it is the Company’s intention to 
settle the exercise of awards through shares 
purchased in the open market on an arm’s 
length basis. Awards granted and settled in 
this way are not included in the Company’s 
headroom and dilution calculation. The 
Group may fund (although it has not yet 
needed to and therefore has not done so) the 
EBT to purchase on the EBT’s own account 
shares in the Company on the open market. 
This is in return for the EBT agreeing to use 
the shares in the Company that it holds to 
satisfy certain outstanding awards made 
under the Company’s share option schemes. 
The purchasing in the market of shares to 

satisfy the exercise of options places a cash 
requirement on the business. To date, no 
shares have been purchased by the Trust for 
satisfaction of outstanding or future share 
option awards.

To further help manage dilution limits, and 
where appropriate and agreed with the 
Committee, share options are net settled 
upon exercise.

Employee share dealing and  
share ownership 
In accordance with AIM Rule 21, all 
employees are made aware of and are 
required to comply with the Company’s Share 
Dealing Policy when dealing in the Company’s 
shares or exercising options over shares. The 
Dealing Code sets out the rules relating to 
close periods, clearance procedures, time 
frames and disclosure requirements. 

The Company operates a share ownership 
policy under which the Executive Directors 
and certain other employees are required, 
when exercising options, to acquire and 
maintain an interest in Alliance Pharma shares 
up to a percentage of base salary, details of 
which can be found on page 70.

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Additional Information

Directors' Report continued

Accounting policies, financial 
instruments and risks
Details of the Group’s financial instruments 
and financial risk management disclosures 
can be found in note 21 of the Group 
financial statements on pages 125 to 129.

Charitable donations
During the year ended 31 December 2021, the 
Group contributed £25,635 (2020: £121,000) 
to charitable causes. 

Political donations
No political donations or contributions were 
made, or political expenditure incurred during 
the period.

Directors’ obligations to the auditor
The Directors confirm that: 

 › So far as each of the Directors is aware, 

there is no relevant audit information of which 
the Company’s auditor is unaware; and

 › They have each taken all the steps that 
they ought to have taken as Directors to 
make themselves aware of any relevant 
audit information and to establish that the 
auditor is aware of that information.

Company’s auditor
The Company intends to undertake a tender 
process for audit services and expects this 
process to be completed by Q3 2022. 
Notwithstanding such process, a resolution to 
re-appoint KPMG LLP will be proposed at this 
year’s Annual General Meeting.

Annual General Meeting
This year’s AGM will be held on 18 May 
2022, the business of which is set out in the 
Notice of Meeting. A circular containing 
the Notice of Meeting together with an 
explanatory letter from the Chairman 
accompanies the Annual Report and is also 
available on the Company’s website. 

Please note that following the Company’s 
move to electronic communications, we are 
no longer producing hard copy forms of 
proxy. These are available on request from 
the Company’s Registrars. 

Electronic communications
Shareholders are encouraged to move away 
from hard copy Company communications. 
This means that, instead of being obliged to 
send Annual Reports, notices of shareholder 
meetings and other documents to shareholders 
in hard copy by post, the Company can 
instead elect to publish them on its website at 
www.alliancepharmaceuticals.com. Using the 
website and email allows us to reduce printing 
and postage costs and it is better for many 
shareholders who can choose and access just 
the information they need, from the website, at 
any time.

Shareholders still have the right to ask for 
paper versions of shareholder information, but 
we are strongly encouraging all shareholders 
to consider the electronic option. 

Shareholders can also vote electronically 
using the following link, www.signalshares.
com. Registering your details on the Link share 
portal also gives shareholders easy access to 
information about their shareholdings and the 
ability to vote at general meetings or appoint 
a proxy to vote. 

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Directors' Report continued

COMPLIANCE WITH THE STREAMLINED ENERGY 
AND CARBON REPORTING REQUIREMENTS

Annual reporting figures 
The total consumption and emissions figures 
for energy supplies reportable by Alliance 
Pharma Plc.

Consumption (kWh) and greenhouse 
gas emissions (tCO2e) totals 
The following figures show the consumption and 
associated emissions for this reporting year for 
our operations, with figures from the previous 
reporting period included for comparison. 

Scope 1 consumption and emissions relate 
to direct combustion of natural gas, and fuels 
utilised for transportation operations, such as 
company vehicle fleets. 

Scope 2 consumption and emissions relate to 
indirect emissions relating to the consumption 
of purchased electricity in day-to-day 
business operations. 

Scope 3 consumption and emissions relate 
to emissions resulting from sources not 
directly owned by us. This relates to grey fleet 
(business travel undertaken in employee-
owned vehicles) only. 

Totals 
The total consumption (kWh) figures for 
reportable energy supplies are shown  
as follows: 

2021 
Consumption 
(kWh)

2020 
Consumption 
(kWh)

Intensity Metric

2021 Intensity 
Metric

2020 Intensity 
Metric

tCO2e/£m turnover

0.70

0.75

Utility and Scope

Grid-supplied electricity 
(Scope 2)

Gaseous and other fuels 
(Scope 1)

Transportation  
(Scope 1 and 3)

Total

256,103

241,399

10,644

10,644

144,186

100,864

410,933

352,907

The total emission (tCO2e) figures for 
reportable energy supplies are set out below. 
Conversion factors utilised in these calculations 
are detailed in the appendix:

2021 
Consumption 
(tCO2e) 

2020 
Consumption 
(tCO2e) 

Utility and Scope

Grid-supplied electricity 
(Scope 2)

Gaseous and other fuels 
(Scope 1)

Transportation  
(Scope 1 and 3)

Total

Energy efficiency improvements 
We are committed to year-on-year 
improvements in our operational energy 
efficiency. As such, a register of energy 
efficiency measures available to us has been 
compiled, with a view to implementing these 
measures in the next five years. 

Measures ongoing and undertaken 
through 2021: 
We have undertaken a programme of 
refurbishment and upgrading works at 
Avonbridge House, including: 

 › Replacement of windows with thermally 
efficient argon-filled double glazing.

54.38

56.27

 › Completion of Air Conditioning upgrade. 

1.95

1.96

33.68

 90.01

23.78

82.01

 › Completion of Light Emitting Diode  

lighting upgrade. 

 ›

Insulation of attic space. 

 › Replacement of atrium glazing. 

Appendix to SECR
Reporting methodology 
Scope 1 and 2 consumption and CO2e 
emission data have been calculated in line 
with the 2019 UK Government environmental 
reporting guidance. The following Emission 
Factor Databases consistent with the 2019 
UK Government environmental reporting 
guidance have been used, utilising the current 
published kWh gross calorific value (CV) 
and kgCO2e emissions factors relevant for 
reporting year 01/01/2021 – 31/12/2021: 

Database 2021, Version 1.0.  
For properties where Alliance Pharma is 
indirectly responsible for utilities (i.e. via a 
landlord or service charge), an average 
kWh/m² consumption was calculated at 
meter level, based upon CIBSE standard 
benchmarks and was applied to the 
properties with similar operations with no 
available data. 

These full year estimations were applied 
to one electricity supply and one gas 
supply. These estimations equated to 7% 
of reported consumption. 

Intensity metric 
An intensity metric of tCO2e per £m turnover 
has been applied for our annual total 
emissions. The methodology of the intensity 
metric calculations are detailed in the 
appendix, and the results of this analysis are 
shown as follows:

Measures prioritised for 
implementation in 2022: 
We are actively looking at options for the 
installation of renewable energy generation 
at our Avonbridge site.

Intensity metrics have been calculated utilising 
the 2021 reportable figures for the following 
metric, and tCO2e for both individual sources 
and total emissions were then divided by this 
figure to determine the tCO2e per metric: 

 › Total turnover (£m) £128m 

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Directors' Report continued

Directors’ Responsibilities Statement
The Directors are responsible for preparing 
the Annual Report and the Group and parent 
Company financial statements in accordance 
with applicable law and regulations.

 › Make judgements and estimates that are 

reasonable, relevant and reliable;

 › State whether they have been prepared in 
accordance with UK-adopted international 
accounting standards; 

Company law requires the Directors to 
prepare Group and parent Company 
financial statements for each financial year. 
Under the AIM Rules of the London Stock 
Exchange they are required to prepare the 
Group financial statements in accordance 
with UK-adopted international accounting 
standards and applicable law and they have 
elected to prepare the parent Company 
financial statements on the same basis.

Under company law, the Directors must not 
approve the financial statements unless they 
are satisfied that they give a true and fair view 
of the state of affairs of the Group and parent 
Company and of the Group’s profit or loss for 
that period. In preparing each of the Group 
and parent Company financial statements, the 
Directors are required to: 

 › Select suitable accounting policies and 

then apply them consistently;

 › Assess the Group and parent Company’s 
ability to continue as a going concern, 
disclosing, as applicable, matters related 
to going concern; and

 › Use the going concern basis of accounting 
unless they either intend to liquidate the 
Group or the parent Company or to cease 
operations, or have no realistic alternative 
but to do so. 

The Directors are responsible for keeping 
adequate accounting records that are 
sufficient to show and explain the parent 
Company’s transactions and disclose with 
reasonable accuracy at any time the financial 
position of the parent Company and enable 
them to ensure that its financial statements 
comply with the Companies Act 2006. They 
are responsible for such internal control as 
they determine is necessary to enable the 
preparation of financial statements that are 

free from material misstatement, whether 
due to fraud or error, and have general 
responsibility for taking such steps as are 
reasonably open to them to safeguard the 
assets of the Group and to prevent and detect 
fraud and other irregularities.

Under applicable law and regulations, the 
Directors are also responsible for preparing a 
Strategic Report and a Directors’ Report that 
comply with that law and those regulations. 

The Directors are responsible for the 
maintenance and integrity of the corporate 
and financial information included on the 
Company’s website. Legislation in the UK 
governing the preparation and dissemination 
of financial statements may differ from 
legislation in other jurisdictions.

Chris Chrysanthou
Company Secretary

30 March 2022

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Financial 
Statements

Independent Auditor’s Report

Consolidated Income Statement

 Consolidated Statement of  
Comprehensive Income

Consolidated Balance Sheet

Company Balance Sheet

Consolidated Statement of Changes in Equity

Company Statement of Changes in Equity

Consolidated and Company Cash  
Flow Statements

Notes to the Financial Statements

86

95

96

97

98

99

100

101

102

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Independent auditor’s report
to the members of Alliance Pharma plc

1. Our opinion is unmodified
We have audited the financial statements of Alliance Pharma plc (the “Company”) for 
the year ended 31 December 2021 which comprise the Consolidated Income Statement, 
Consolidated Statement of Comprehensive Income, Consolidated Balance Sheet, Company 
Balance Sheet, Consolidated Statement of Changes in Equity, Company Statement of 
Changes in Equity, Consolidated and Company cash flow statements and the related notes, 
including the accounting policies in note 2. 

In our opinion: 
 ›

the financial statements give a true and fair view of the state of the Group’s and of the 
parent Company’s affairs as at 31 December 2021 and of the Group’s profit for the year 
then ended;

 ›

 ›

 ›

the Group financial statements have been properly prepared in accordance with UK-
adopted international accounting standards; 

the parent Company financial statements have been properly prepared in accordance with 
UK-adopted international accounting standards and as applied in accordance with the 
provisions of the Companies Act 2006; and

the financial statements have been prepared in accordance with the requirements of the 
Companies Act 2006. 

Basis for opinion 
We conducted our audit in accordance with International Standards on Auditing (UK) (“ISAs 
(UK)”) and applicable law. Our responsibilities are described below. We have fulfilled our 
ethical responsibilities under, and are independent of the Group in accordance with, UK ethical 
requirements including the FRC Ethical Standard as applied to listed entities. We believe that the 
audit evidence we have obtained is a sufficient and appropriate basis for our opinion. 

Overview

Materiality: group financial  
statements as a whole

£1.5m (2020: £1.5m)

4.7% (2020: 4.7%) of normalised Group profit before tax

Coverage

96% (2020: 92%) of group profit before tax

Key audit matters vs 2020

Recurring risks

Impairment of intangible brand assets

Recoverability of parent company’s investment in subsidiaries

Event driven

New: CMA infringement decision

New: Accounting treatment of costs related to cloud-based 
software arrangements

2. Key audit matters: our assessment of risks of material misstatement
Key audit matters are those matters that, in our professional judgement, were of most 
significance in the audit of the financial statements and include the most significant assessed 
risks of material misstatement (whether or not due to fraud) identified by us, including those 
which had the greatest effect on: the overall audit strategy; the allocation of resources in the 
audit; and directing the efforts of the engagement team. These matters were addressed in the 
context of our audit of the financial statements as a whole, and in forming our opinion thereon, 
and we do not provide a separate opinion on these matters. In arriving at our audit opinion 
above, the key audit matters, in decreasing order of audit significance, were as follows:

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Independent auditor’s report continued

2. Key audit matters: our assessment of risks of material misstatement continued

The risk

Our response

The risk

Our response

Impairment of 
Intangible  
Brand Assets

(£368.8 million;  
2020: £381.6 million)

Refer to page 63 
(Audit Committee 
Report), page 105 
(accounting policy) 
and page 115 
(financial disclosures.

Forecast-based assessment:

The estimated recoverable amount 
of intangible assets (excluding 
Goodwill and Computer Software) 
is subjective due to the inherent 
uncertainty involved in forecasting 
and discounting future cash flows. 

This assessment is based on 
assumptions (such as forecast cash 
flows, discount rates and, in the case 
of finite life assets, the period over 
which management have forecast 
cashflows), which are inherently 
highly judgemental. 

For all CGUs, we held discussions with the directors, 
commercial, regulatory and financial management 
and considered information about the products 
available in the public domain. For higher risk CGUs 
our procedures included: 

 › Benchmarking assumptions: Using our 
own valuations specialist, we challenged the 
Group’s selection of discount and growth rates by 
comparing those used to externally derived data. 
In addition, we assessed whether the forecasts 
(including growth rate) were consistent with current 
business strategies in place and information about 
the products available in the public domain, and 
that the selected useful economic lives for finite life 
assets were appropriate; 

CMA infringement 
decision

(£7.9 million; 2020: 
£Nil)

Refer to page 63 
(Audit Committee 
Report), page 102 
(accounting policy) 
and page 124 
(financial disclosures).

The Group has a total of 53 CGUs, 
from which our risk has been 
identified in respect of 3, which hold 
an aggregate value of £10.8 million. 

 ›

Given the quantum of the balance 
in relation to our materiality and 
the inherent estimation uncertainty, 
we concluded this to be our most 
significant Key Audit Matter. 

The affect of these matters is that, 
as part of our risk assessment, we 
determined that the value in use 
across the portfolio has a high 
degree of estimation uncertainty 
with a potential range of reasonable 
outcomes greater than our materiality 
for the financial statements as a 
whole. The financial statements (Note 
11) disclose the range/sensitivity 
estimated by the Group. 

Sensitivity analysis: We performed our own 
analysis to assess the sensitivity of the impairment 
reviews to changes in the key assumptions, 
including the discount rate, growth rate, useful 
economic lives, and the forecast cash flows; 

 › Historical comparisons: We compared the 

previously forecast cash flows to actual results to 
assess the historical accuracy of forecasting; 

 › Assessing transparency: We assessed the 

adequacy of the Group’s disclosures in respect of 
the sensitivity to changes in key assumptions. 

For CGUs which we determined were not higher  
risk, we performed historical comparisons and 
sensitivity analysis to ensure our risk assessment  
was appropriate.

We performed the tests above rather than seeking 
to rely on any of the group’s controls because the 
nature of the balance is such that we would expect 
to obtain audit evidence primarily through the 
detailed procedures described.

Dispute outcome:

Our procedures included: 

 ›

Enquiry of lawyers: Discussions with and 
inquires of the Group’s in-house and external 
legal advisors, the directors and management; 

 › Our compliance expertise: Using our own 
forensic and compliance specialists, critically 
assessed the judgements taken by the Directors, 
and monitored external sources of information;

 › Assessing transparency: Assessing whether 
the Group’s disclosures detailing the regulatory 
proceedings adequately disclose the potential 
liabilities of the Group; 

 › Accounting analysis: Assessing the 

directors analysis of whether the receipt of the 
infringement decision was an adjusting or non-
adjusting subsequent event. 

We performed the tests above rather than seeking 
to rely on any of the group’s controls because the 
nature of the balance is such that we would expect 
to obtain audit evidence primarily through the 
detailed procedures described.

As explained in note 20, the Group 
received an infringement decision 
and fine of £7.9 million from the 
Competition and Markets Authority 
(the “CMA”) on 3 February 
2022 relating to suspected anti-
competitive agreements in relation to 
Prochlorperazine, which covered the 
period from June 2013 to July 2018. 

The amounts involved are significant, 
and the application of accounting 
standards to determine the amount 
to be provided as a liability, is 
inherently subjective. The provision 
of £7.9 million recognised could 
be released in entirety if the Group 
is successful at appeal, or a lower 
amount agreed by the appeal.

Following the issuance of an 
infringement notice by the CMA,  
this risk has increased.

We have identified this matter as a 
risk of error and a risk of fraud due 
to perceived impact on the Group’s 
share price.

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2. Key audit matters: our assessment of risks of material misstatement continued

The risk

Our response

The risk

Our response

Accounting 
treatment of costs 
related to cloud-
based software 
arrangements

(£15.0 million; 2020: 
£11.0 million)

Refer to page 63 
(Audit Committee 
Report), page 103 
(accounting policy) 
and page 115 
(financial disclosures).

Accounting treatment:

Our procedures included: 

 › Accounting clarity: We assessed the 

accounting clarification of the IFRIC April 
2021 decision against the Group’s treatment 
of capitalised ERP costs, including reviewing 
contractual documentation; 

 › Our IT expertise: In conjunction with the IT 
auditors, the audit team sought input from ERP 
implementation professionals on the practical 
and technical aspects of transferring the ERP 
from the cloud onto the company’s servers;

 › Assessing transparency: We assessed the 
adequacy of the Group’s related disclosures in 
respect of the judgements taken by management.

We performed the tests above rather than seeking 
to rely on any of the group’s controls because the 
nature of the balance is such that we would expect 
to obtain audit evidence primarily through the 
detailed procedures described.

The Group has capitalised 
internal and external costs in 
respect of cloud-based software 
arrangements. In April 2021 the 
IFRS Interpretations Committee 
(‘IFRIC’) published an agenda 
decision on accounting for cloud 
computing costs. 

This IFRIC decision has been 
considered by the Group and 
the Group have concluded that 
no change in respect of the 
capitalisation of certain costs 
associated with their Enterprise 
Resource Planning (ERP) system  
is required. 

In assessing whether a change in 
accounting policy is required, the 
Group has exercised significant 
judgement in reaching a conclusion. 

The risk is that a potential change 
in accounting policy has not 
appropriately been identified and 
applied to both the current and 
prior years. 

Recoverability of 
parent company’s 
investment in 
subsidiaries

(£199.3 million; 
2020: £199.8 million)

Refer to page 63 
(Audit Committee 
Report), page 108 
(accounting policy) 
and page 121 
(financial disclosures).

Low risk, high value:

Our procedures included: 

 ›

The carrying amount of the 
parent company’s investments 
in subsidiaries represents 99.9% 
(2020: 99.9%) of the company’s 
total assets. 

Their recoverability is not at a high 
risk of significant misstatement or 
subject to significant judgement. 
However, due to their materiality in 
the context of the parent company 
financial statements, this is 
considered to be the area that had 
the greatest effect on our overall 
parent company audit. 

Test of detail: We compared the carrying 
amount of 100% of the investments with the 
net asset value of the respective subsidiaries, 
being an approximation that their minimum 
recoverable amount, to identify whether 
the net asset values were in excess of the 
carrying amounts and assessed whether those 
subsidiaries have historically been profit making. 
The Group audit team performs the statutory 
audit of all material investments; 

We performed the test above rather than seeking 
to rely on any of the group’s controls because the 
nature of the balance is such that we would expect 
to obtain audit evidence primarily through the 
detailed procedure described.

We continue to perform procedures over the selection of useful economic lives for intangible 
assets. However, following a consistent application of accounting policy in the current year, 
we have not assessed this as one of the most significant risks in our current year audit and, 
therefore, it is not separately identified in our report this year.

We also continue to perform procedures over Goodwill, however, due to the absence of 
significant acquisitions in the current year and the significant levels of headroom present, we 
have not included it within this risk in our report this year

We also continue to consider the need for procedures over Business combinations: valuation 
of identified intangible assets. However, due to no business combinations having occurred in 
the current year, we have not assessed this as one of the most significant risks in our current 
year audit and, therefore, it is not separately identified in our report this year.

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Independent auditor’s report continued

3. Our application of materiality and an overview of the scope of our audit
Materiality for the Group financial statements as a whole was set at £1.5m (2020: £1.5m), 
determined with reference to a benchmark of Group profit before tax, normalised to 
exclude the impairment of intangible assets, as disclosed in note 5, of £6.15m and the CMA 
provision, also disclosed in note 5, of £7.9m (2020: normalised to exclude the impairment 
and amortisation of intangible assets, as disclosed in note 5, of £19.2m), of which it represents 
4.7% (2020: 4.7%)

Materiality for the parent Company financial statements as a whole was set at £0.9m (2020: 
£1.4m), determined with reference to a benchmark of Company total assets, of which it 
represents 0.5% (2020: 0.7%).

In line with our audit methodology, our procedures on individual account balances and 
disclosures were performed to a lower threshold, performance materiality, so as to reduce to 
an acceptable level the risk that individually immaterial misstatements in individual account 
balances add up to a material amount across the financial statements as a whole.

Performance materiality was set at 75% (2020: 75%) of materiality for the financial 
statements as a whole, which equates to £1.125m (2020: £1.125m) for the Group and 
£0.675m (2020: £1.05m) for the parent Company. We applied this percentage in our 
determination of performance materiality because we did not identify any factors indicating 
an elevated level of risk

We agreed to report to the Audit Committee any corrected or uncorrected identified 
misstatements exceeding £75,000 (2020: £75,000), in addition to other identified 
misstatements that warranted reporting on qualitative grounds.

Of the Group’s 17 (2020: 19) reporting components, we subjected 3 (2020: 3) to full scope 
audits for group purposes and 1 (2020: 0) to an audit of account balances over revenue, 
trade receivables and cash and cash equivalents. The component for which we performed an 
audit of account balances was not individually significant but was included in the scope of our 
group reporting work in order to provide further coverage over the group’s results. 

The scope of the audit work performed was fully substantive as we did not rely upon the 
Group’s internal control over financial reporting.

The components within the scope of our work accounted for the percentages illustrated 
opposite.

The remaining 8% (2020: 11%) of total Group revenue, 4% (2020: 8%) of Group profit before 
tax and 11% (2020: 2%) of total Group assets is represented by 13 (2020: 14) of reporting 
components, none of which individually represented more than 10% (2020: 10%) of any of 
total Group revenue, Group profit before tax or total Group assets. For these components, 
we performed analysis at an aggregated group level to re-examine our assessment that there 
were no significant risks of material misstatement within these.

Normalised group profit before tax 
£32.2m (2020: £32.2m)

Group materiality 
£1.5m (2020: £1.5m)

£1.5m 
Whole financial statements materiality  
(2020: £1.5m)
£1.125m 
Whole financial statements performance materiality  
(2020: £1.125m)

£1.1m 
Range of materiality at 4 components (£0.2m–£1.1m) 
(2020: £0.6m to £1.0m)

£75,000 
Misstatements reported to the audit committee  
(2020: £75,000)

  Normalised PBT

  Group materiality

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3. Our application of materiality and an overview of the scope of our audit continued

Group revenue

8%

11%

8%

92%

(2020 89%)

89%

84%

Group total assets

11%

2%

3%

89%

(2020 98%)

98%

86%

Group profit before tax

1% 4%

8%

96%

(2020 92%)

92%

95%

  Full scope for group audit purposes 2021

  Audit of account balances 2021

  Full scope for group audit purposes 2020

  Residual components

The Group team instructed component auditors as to the significant areas to be covered, 
including the relevant risks detailed above and the information to be reported back. The 
Group team approved the component materialities, which ranged from £0.2m to £1.1m 
(2020: £0.6m to £1.0m), having regard to the mix of size and risk profile of the Group across 
the components. The work on 1 of the 4 components (2020: 1 of the 4 components) was 
performed by component auditors and the rest, including the audit of the parent Company, 
was performed by the Group team. The Group team performed procedures on the items 
excluded from normalised Group profit before tax. 

Other than the UK, the Group team visited one component location in the USA (2020: nil) 
during the year to perform audit procedures. Video and telephone conference meetings were 
also held with the component auditor for the component that was not physically visited. At 
these meetings, the findings reported to the Group team were discussed in more detail, and 
any further work required by the Group team was then performed by the component auditor. 

4. Going concern
The Directors have prepared the financial statements on the going concern basis as they 
do not intend to liquidate the Group or the Company or to cease their operations, and as 
they have concluded that the Group and the Company’s financial position means that this is 
realistic. They have also concluded that there are no material uncertainties that could have 
cast significant doubt over their ability to continue as a going concern for at least a year from 
the date of approval of the financial statements (“the going concern period”). 

We used our knowledge of the Group, its industry, and the general economic environment to 
identify the inherent risks to its business model and analysed how those risks might affect the 
Group’s and Company’s financial resources or ability to continue operations over the going 
concern period. The risks that we considered most likely to adversely affect the Group’s and 
Company’s available financial resources and/or metrics relevant to debt covenants over this 
period were: 

 › The impact on customer confidence as a result of a slowdown in the Global economy; 

 › Constraints on supply chain, sourcing or logistics and the impact it could have on the 

Group’s key products; 

 › The impact that changes in product regulation could have on the ability to sell new or 

existing products; and

 › The impact of the settlement of the penalty relating to the CMA infringement decision. 

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Independent auditor’s report continued

4. Going concern continued
We considered whether these risks could plausibly affect the liquidity or covenant compliance 
in the going concern period by comparing severe, but plausible downside scenarios that 
could arise from these risks individually and collectively against the level of available financial 
resources and covenants indicated by the Group’s financial forecasts.

5. Fraud and breaches of laws and regulations – ability to detect
Identifying and responding to risks of material misstatement due to fraud
To identify risks of material misstatement due to fraud (“fraud risks”) we assessed events 
or conditions that could indicate an incentive or pressure to commit fraud or provide an 
opportunity to commit fraud. Our risk assessment procedures included:

Our procedures also included a critical assessment of the assumptions in the Group’s base 
case and downside scenarios, in particular in relation to the recent geopolitical instability and 
the ongoing COVID-19 pandemic on the economic situation worldwide (and its impact on the 
Group), and our knowledge of the entity and the sector in which it operates. 

 › Enquiring of directors, and the audit committee, and inspection of policy documentation 

as to the Group’s high-level policies and procedures to prevent and detect fraud, including 
the Group’s channel for “whistleblowing”, as well as whether they have knowledge of any 
actual, suspected or alleged fraud;

We considered whether the going concern disclosure in note 2.18 to the financial statements 
gives a full and accurate description of the directors’ assessment of going concern, including 
the identified risks.

Our conclusions based on this work:

 › We consider that the directors’ use of the going concern basis of accounting in the 

preparation of the financial statements is appropriate;

 › We have not identified, and concur with the directors’ assessment that there is not, a 

material uncertainty related to events or conditions that, individually or collectively, may 
cast significant doubt on the Group’s or Company’s ability to continue as a going concern 
for the going concern period; and

 › We found the going concern disclosure in note 2.18 to be acceptable.

However, as we cannot predict all future events or conditions and as subsequent events may result 
in outcomes that are inconsistent with judgements that were reasonable at the time they were 
made, the above conclusions are not a guarantee that the Group will continue in operation. 

 › Reading Board and Audit Committee meeting minutes;

 › Considering remuneration incentive schemes and performance targets for management 

and the directors;

 › Using analytical procedures to identify any unusual or unexpected relationships; and

 › Using our own forensic specialists to assist us in identifying fraud risks based on discussions 

of the circumstances of the Group.

We communicated identified fraud risks throughout the audit team and remained alert to any 
indications of fraud throughout the audit. This included communication from the Group audit 
team to component audit teams of relevant fraud risks identified at the Group level and a 
request to full scope component audit teams to report to the Group audit team any instances 
of fraud that could give rise to a material misstatement at the Group level. 

As required by auditing standards, and taking into account possible pressures to meet profit 
targets, we perform procedures to address the risk of management override of controls and 
the risk of fraudulent revenue recognition, in particular:

 › The risk that Group and component management may be in a position to make 

inappropriate accounting entries; and

 › The risk that revenue is overstated through recording of revenues in the wrong period

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Additional Information

Independent auditor’s report continued

5. Fraud and breaches of laws and regulations – ability to detect continued
Identifying and responding to risks of material misstatement due to fraud continued
We also identified a fraud risk related to the CMA infringement decision, in response 
to a perceived impact on the Group’s share price. Further detail in respect of the CMA 
infringement decision is set out in the key audit matter disclosures in section 2 of this report.
We performed procedures including: 
 ›

Identifying journal entries and other adjustments to test for all full scope components based 
on risk criteria and comparing the identified entries to supporting documentation. These 
included those posted to unusual accounts, and journal descriptions containing specific  
key words; 

 › Evaluating the business purpose of significant unusual transactions; and 

 › Assessing significant accounting estimates for bias

Identifying and responding to risks of material misstatement due to non-
compliance with laws and regulations
We identified areas of laws and regulations that could reasonably be expected to have a 
material effect on the financial statements from our general commercial and sector experience, 
through discussion with the directors (as required by auditing standards), and discussed with the 
directors the policies and procedures regarding compliance with laws and regulations. 

We communicated identified laws and regulations throughout our team and remained alert 
to any indications of non-compliance throughout the audit. This included communication from 
the group to component audit teams of relevant laws and regulations identified at the Group 
level, and a request for component auditors to report to the group team any instances of non-
compliance with laws and regulations that could give rise to a material misstatement at group. 

The potential effect of these laws and regulations on the financial statements varies considerably. 

Firstly, the Group is subject to laws and regulations that directly affect the financial statements 
including financial reporting legislation (including related companies legislation), distributable 
profits legislation and taxation legislation, and we assessed the extent of compliance with these 
laws and regulations as part of our procedures on the related financial statement items. 

Secondly, the Group is subject to many other laws and regulations where the consequences 
of non-compliance could have a material effect on amounts or disclosures in the financial 
statements, for instance through the imposition of fines or litigation. We identified the following 
areas as those most likely to have such an effect: health and safety, anti-bribery, competition 
laws, employment law, product regulation and certain aspects of company legislation 
recognising the nature of the Group’s activities. Auditing standards limit the required audit 
procedures to identify non-compliance with these laws and regulations to enquiry of the 
directors and inspection of regulatory and legal correspondence, if any. Therefore if a breach of 
operational regulations is not disclosed to us or evident from relevant correspondence, an audit 
will not detect that breach. 

Further detail in respect of CMA infringement decision is set out in the key audit matter 
disclosures in section 2 of this report.

Context of the ability of the audit to detect fraud or breaches of law or regulation
Owing to the inherent limitations of an audit, there is an unavoidable risk that we may not 
have detected some material misstatements in the financial statements, even though we 
have properly planned and performed our audit in accordance with auditing standards. For 
example, the further removed non-compliance with laws and regulations is from the events 
and transactions reflected in the financial statements, the less likely the inherently limited 
procedures required by auditing standards would identify it. 

In addition, as with any audit, there remained a higher risk of non-detection of fraud, as these 
may involve collusion, forgery, intentional omissions, misrepresentations, or the override of 
internal controls. Our audit procedures are designed to detect material misstatement. We are 
not responsible for preventing non-compliance or fraud and cannot be expected to detect 
non-compliance with all laws and regulations.

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Financial Statements

Additional Information

Independent auditor’s report continued

6. We have nothing to report on the other information in the Annual Report
The directors are responsible for the other information presented in the Annual Report 
together with the financial statements. Our opinion on the financial statements does not cover 
the other information and, accordingly, we do not express an audit opinion or, except as 
explicitly stated below, any form of assurance conclusion thereon. 

Our responsibility is to read the other information and, in doing so, consider whether, based 
on our financial statements audit work, the information therein is materially misstated or 
inconsistent with the financial statements or our audit knowledge. Based solely on that work 
we have not identified material misstatements in the other information. 

Strategic report and directors’ report 
Based solely on our work on the other information:

 › we have not identified material misstatements in the strategic report and the directors’ report; 

 ›

 ›

in our opinion the information given in those reports for the financial year is consistent with  
the financial statements; and 

in our opinion those reports have been prepared in accordance with the Companies  
Act 2006.

7. We have nothing to report on the other matters on which we are required to 
report by exception 
Under the Companies Act 2006, we are required to report to you if, in our opinion: 

 › adequate accounting records have not been kept by the parent Company, or returns 
adequate for our audit have not been received from branches not visited by us; or 

 ›

the parent Company financial statements are not in agreement with the accounting records 
and returns; or 

 › certain disclosures of directors’ remuneration specified by law are not made; or 

 › we have not received all the information and explanations we require for our audit. 

We have nothing to report in these respects. 

8. Respective responsibilities
Directors’ responsibilities 
As explained more fully in their statement set out on page 84, the directors are responsible 
for: the preparation of the financial statements including being satisfied that they give a true 
and fair view; such internal control as they determine is necessary to enable the preparation 
of financial statements that are free from material misstatement, whether due to fraud or error; 
assessing the Group and parent Company’s ability to continue as a going concern, disclosing, 
as applicable, matters related to going concern; and using the going concern basis of 
accounting unless they either intend to liquidate the Group or the parent Company or to cease 
operations, or have no realistic alternative but to do so.

Auditor’s responsibilities 
Our objectives are to obtain reasonable assurance about whether the financial statements as 
a whole are free from material misstatement, whether due to fraud or error, and to issue our 
opinion in an auditor’s report. Reasonable assurance is a high level of assurance, but does not 
guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material 
misstatement when it exists. Misstatements can arise from fraud or error and are considered 
material if, individually or in aggregate, they could reasonably be expected to influence the 
economic decisions of users taken on the basis of the financial statements. 

A fuller description of our responsibilities is provided on the FRC’s website at  
www.frc.org.uk/auditorsresponsibilities. 

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Additional Information

Independent auditor’s report continued

9. The purpose of our audit work and to whom we owe our responsibilities 
This report is made solely to the Company’s members, as a body, in accordance with Chapter 
3 of Part 16 of the Companies Act 2006. Our audit work has been undertaken so that we 
might state to the Company’s members those matters we are required to state to them in an 
auditor’s report and for no other purpose. To the fullest extent permitted by law, we do not 
accept or assume responsibility to anyone other than the Company and the Company’s 
members, as a body, for our audit work, for this report, or for the opinions we have formed.

Huw Brown
(Senior Statutory Auditor) 

for and on behalf of KPMG LLP, Statutory Auditor  
Chartered Accountants  
66 Queen Square,  
Bristol,  
BS1 4BE

30 March 2022

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Financial Statements

Additional Information

Consolidated Income Statement

Revenue

Cost of sales

Gross profit

Operating expenses

Administration and marketing expenses

Amortisation of intangible assets

Impairment of goodwill and intangible assets

CMA provision

Share-based employee remuneration

Operating profit 

Finance costs

Interest payable and similar charges

Finance income/(costs)

Profit before taxation

Taxation

Profit for the period attributable to  
equity shareholders

Earnings per share

Basic (pence)

Diluted (pence)

Note

3,34

5

5

5

20

7, 24

6

6

4

8

10

10

Year ended 31 December 2021

Year ended 31 December 2020

Underlying
£000s

163,207

(53,757)

109,450

(60,202)

(1,362)

–

–

(2,250)

45,636

(3,646)

228

(3,418)

42,218

(8,033)

Non-underlying
£000s 
(Note 5)

Total
£000s

Underlying
£000s

Non-underlying
£000s 
(Note 5)

–

–

–

163,207

(53,757)

109,450

129,801

(46,985)

82,816

(2,843)

(7,168)

(6,150)

(7,900)

–

(24,061)

–

–

–

(24,061)

(2,805)

(63,045)

(44,614)

(8,530)

(6,150)

(7,900)

(2,250)

21,575

(3,646)

228

(3,418)

18,157

(10,838)

–

–

–

(1,374)

36,828

(2,657)

(643)

(3,300)

33,528

(6,372)

–

–

–

(1,300)

(7,155)

(12,057)

–

–

(20,512)

–

–

–

(20,512)

1,383

Total
£000s

129,801

(46,985)

82,816

(45,914)

(7,155)

(12,057)

–

(1,374)

16,316

(2,657)

(643)

(3,300)

13,016

(4,989)

34,185

(26,866)

7,319

27,156

(19,129)

8,027

6.39

6.30

1.37

1.35

5.11

5.05

1.51

1.49

All of the activities of the Group are 
classed as continuing.

The accompanying accounting policies  
and notes form an integral part of these 
financial statements.

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Financial Statements

Additional Information

Consolidated Statement of Comprehensive Income

Profit for the year

Other comprehensive income

Items that may be reclassified to profit or loss

Foreign exchange translation differences (net of deferred tax)

Foreign exchange forward contracts – cash flow hedge (net of deferred tax)

Interest rate swaps – cash flow hedge (net of deferred tax)

Total comprehensive income for the year

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

7,319

8,027

636

(191)

–

7,764

(1,051)

(250)

27

6,753

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Financial Statements

Additional Information

Consolidated Balance Sheet

Assets

Non-current assets

Goodwill and intangible assets

Property, plant and equipment

Deferred tax asset

Other non-current assets

Current assets

Inventories

Trade and other receivables

Derivative financial instruments

Cash and cash equivalents 

Total assets

Equity

Ordinary share capital

Share premium account

Share option reserve

Other reserve

Cash flow hedging reserve

Translation reserve

Retained earnings

Total equity

Note

31 December 2021
£000s

31 December 2020
£000s

Note

31 December 2021
£000s

31 December 2020
£000s

11

12

22

14

15

21

16

23

413,744

4,826

3,526

371

412,872

15,921

2,139

682

Liabilities

Non-current liabilities

Loans and borrowings

Other liabilities

Deferred tax liability

422,467

431,614

Current liabilities

21,075

30,821

64

29,061

81,021

22,917

25,114

310

28,898

77,239

Corporation tax

Trade and other payables 

Provisions

Derivative financial instruments

Total liabilities

503,488

508,853

Total equity and liabilities

18

19

22

17

20

21

116,060

2,637

61,728

180,425

1,178

29,930

9,469

–

40,577

221,002

503,488

138,328

3,200

56,181

197,709

1,435

28,736

–

15

30,186

227,895

508,853

5,382

151,328

10,058

(329)

48

(419)

116,418

282,486

5,329

150,645

8,426

(329)

239

(1,055)

117,703

280,958

The financial statements were approved by the Board of Directors on 30 March 2022.

Peter Butterfield 
Director   

Andrew Franklin
Director

The accompanying accounting policies and notes form an integral part of these  
financial statements. 

Company number 04241478

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Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
 
Company Overview

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Financial Statements

Additional Information

Company Balance Sheet

Assets

Non-current assets

Investment and loans to subsidiaries

Current assets

Trade and other receivables

Cash and cash equivalents

Total assets

Equity

Ordinary share capital

Share premium account

Share option reserve

Retained earnings

Total equity

Liabilities

Current liabilities

Trade and other payables 

Corporation tax

Total liabilities

Note

31 December 2021
 £000s

31 December 2020
 £000s

The Company’s profit for the year was £6,756,000 (2020: £5,433,000).

As permitted by section 408 of the Companies Act 2006, no separate Income Statement  
is presented in respect of the Parent Company.

13

15

16

23

17

199,348

199,776

The financial statements were approved by the Board of Directors on 30 March 2022.

Peter Butterfield 
Director   

Andrew Franklin
Director

The accompanying accounting policies and notes form an integral part of these  
financial statements. 

Company number 04241478

39

141

180

36

297

333

199,528

200,109

5,382

151,328

8,962

33,064

198,736

368

424

792

5,329

150,645

7,955

34,912

198,841

306

962

1,268

Total equity and liabilities

199,528

200,109

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Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
 
Ordinary 
share 
capital
£000s

Share 
premium 
account 
£000s

 Other 
reserve
£000s

Cash flow 
hedging 
reserve
£000s

Translation 
reserve 
£000s

Share 
option 
reserve
£000s

Retained 
earnings 
£000s

Total  
equity
£000s

Ordinary 
share 
capital
£000s

Share 
premium 
account 
£000s

 Other 
reserve
£000s

Cash flow 
hedging 
reserve
£000s

Translation 
reserve 
£000s

Share 
option 
reserve
£000s

Retained 
earnings 
£000s

Total  
equity
£000s

5,294 149,036

(329)

462

(4)

7,208 112,513 274,180

Balance 1 January 
2021

5,329 150,645

(329)

239

(1,055)

8,426 117,703 280,958

–

1,644

Issue of shares

53

683

Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Consolidated Statement of Changes in Equity

Balance 1 January 
2020

Issue of shares

Dividend paid

Share options charge 
(including deferred tax)

Transactions  
with owners

Profit for the year

Other 
comprehensive 
income

Foreign exchange 
forward contracts – 
cash flow hedge  
(net of deferred tax)

Interest rate swaps – 
cash flow hedge  
(net of deferred tax)

Foreign exchange 
translation differences 
(net of deferred tax)

Total comprehensive 
income for the year

Balance 
31 December 2020

35

1,609

–

–

35

–

–

–

1,609

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

(250)

27

–

–

–

–

–

–

–

–

(1,051)

(223)

(1,051)

–

–

(2,837)

(2,837)

Dividend paid

1,218

–

1,218

1,218

(2,837)

25

Share options charge 
(including deferred tax)

Transactions  
with owners

–

8,027

8,027

Profit for the year

Other 
comprehensive 
income

Foreign exchange 
forward contracts – 
cash flow hedge  
(net of deferred tax)

Foreign exchange 
translation differences 
(net of deferred tax)

Total comprehensive 
income for the year

Balance 
31 December 2021

–

–

–

–

–

–

(250)

27

–

(1,051)

8,027

6,753

5,329 150,645

(329)

239

(1,055)

8,426 117,703 280,958

–

–

53

–

–

–

–

–

–

683

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

736

(8,604)

(8,604)

1,632

–

1,632

1,632

(8,604)

(6,236)

–

7,319

7,319

(191)

–

–

636

(191)

636

–

–

–

–

–

(191)

636

7,319

7,764

5,382 151,328

(329)

48

(419) 10,058 116,418 282,486

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Financial Statements

Additional Information

Company Statement of Changes in Equity

Ordinary share capital
£000s

Share premium account
£000s 

Share option reserve
£000s

Retained earnings
£000s 

Balance 1 January 2020

Issue of shares

Dividend paid

Share options charge (including deferred tax)

Transactions with owners

Profit for the period and total comprehensive income

Balance 31 December 2020

5,294

35

–

–

35

–

5,329

149,036

1,609

–

–

1,609

–

150,645

Balance 1 January 2021

5,329

150,645

Issue of shares

Dividend paid

Share options charge (including deferred tax)

Transactions with owners

Profit for the period and total comprehensive income

53

–

–

53

–

683

–

–

683

–

Balance 31 December 2021

5,382

151,328

6,846

–

–

1,109

1,109

–

7,955

7,955

–

–

1,007

1,007

–

8,962

32,316

–

(2,837)

–

(2,837)

5,433

34,912

34,912

–

(8,604)

–

(8,604)

6,756

33,064

Total equity
£000s

193,492

1,644

(2,837)

1,109

(84)

5,433

198,841

198,841

736

(8,604)

1,007

(6,862)

6,756

198,736

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Financial Statements

Additional Information

Consolidated and Company Cash Flow Statements

Cash flows from operating activities

Cash generated from operations

Tax paid

Cash flows from/(used in) operating activities

Investing activities

Interest received

Dividend received

Acquisition of Biogix Inc

Purchase of intangible assets

Purchase of property, plant and equipment

Proceeds from disposal of intangibles 

Net cash (used in)/from investing activities

Financing activities

Interest paid and similar charges 

Loan issue costs

Capital lease payments 

Contribution from/(investment in) subsidiary

Proceeds from exercise of share options

Dividend paid

Proceeds from borrowings

Repayment of borrowings

Net cash provided by/(used in) financing activities

Net movement in cash and cash equivalents

Cash and cash equivalents at 1 January

Exchange gains/(losses) on cash and cash equivalents

Cash and cash equivalents at 31 December

Note

25

31

11

12

13

9

21

21

16

Group

Company

Year ended
31 December 2021
£000s

Year ended
31 December 2020
£000s

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

The accompanying accounting 
policies and notes form an integral 
part of these financial statements. 

44,919

(6,260)

38,659

–

–

183

(4,006)

(1,526)

750

(4,599)

(2,965)

–

(924)

–

736

(8,604)

–

(22,587)

(34,344)

(284)

28,898

447

29,061

46,405

(4,838)

41,567

10

–

(82,667)

–

(4,612)

1,405

(85,864)

(2,866)

(362)

(884)

–

1,644

(2,837)

82,595

(21,541)

55,749

11,452

17,830

(384)

28,898

(961)

(1,484)

(2,445)

–

2,600

–

–

–

–

(2,133)

(1,012)

(3,145)

–

2,800

–

–

–

–

2,600

2,800

–

–

–

7,557

736

(8,604)

–

–

(311)

(156)

297

–

141

–

–

–

1,738

1,644

(2,837)

–

–

(545)

200

97

–

297

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Financial Statements

Additional Information

Notes to the Financial Statements

1. General information
Alliance Pharma plc (‘the Company’) and its 
subsidiaries (together ‘the Group’) acquire, 
market and distribute consumer healthcare 
products and prescription medicines. The 
Company is a public limited company, 
limited by shares, registered, incorporated 
and domiciled in England and Wales in the 
UK. The address of its registered office is 
Avonbridge House, Bath Road, Chippenham, 
Wiltshire, SN15 2BB. The Company is listed 
on the AIM stock exchange.

These consolidated financial statements have 
been approved for issue by the Board of 
Directors on 30 March 2022.

2. Summary of significant  
accounting policies
The principal accounting policies applied in 
the preparation of these consolidated financial 
statements are set out below. These policies 
have been consistently applied to all the 
periods presented, unless otherwise stated.

2.1 Basis of preparation
These financial statements have been 
prepared and approved by the Directors in 
accordance with UK-adopted international 
accounting standards (‘UK-adopted IFRS’).

The financial statements have been prepared 
under the historical cost convention, with the 
exception of derivatives which are included at 
fair value. 

2.2 Consolidation
The Group financial statements consolidate 
those of the Company and its subsidiaries 
(together referred to as the ‘Group’) and 
equity account the Group’s interest in Joint 
Ventures. The parent Company financial 
statements present information about the 
Company as a separate entity and not about 
the Group.

Subsidiaries
Subsidiaries are entities controlled by the 
Group. The Group controls an entity when 
it is exposed to, or has rights to, variable 
returns from its involvement with the entity 
and has the ability to affect those returns 
through its power over the entity. In assessing 
control, the Group takes into consideration 
potential voting rights. The acquisition date 
is the date on which control is transferred 
to the acquirer. The financial statements of 
subsidiaries are included in the consolidated 
financial statements from the date that control 
commences until the date that control ceases.

Joint ventures
An entity is treated as a joint venture where 
the Group has rights to the net assets of the 
arrangement, rather than rights to its assets 
and obligations for its liabilities. Joint ventures 
are accounted for using the equity method 
(equity accounted investees) and are initially 
recognised at cost. The consolidated financial 
statements include the Group’s share of the 
total comprehensive income and equity 
movements of equity accounted investees, 
from the date that joint control commences 
until the date that joint control ceases.

Transactions eliminated on consolidation
Intra-Group balances and transactions, and 
any unrealised income and expenses arising 
from intra-Group transactions, are eliminated. 

2.3 Judgements and estimates
The preparation of the consolidated financial 
statements requires the Directors to make 
judgements, estimates and assumptions 
that affect the application of policies and 
reported amounts of assets and liabilities, 
income and expenses. The estimates and 
associated assumptions are based on historical 
experience and various other factors that are 
believed to be reasonable under the relevant 
circumstances. Actual results may differ from 
these estimates. 

The estimates and underlying assumptions 
are reviewed by the Directors on an 
ongoing basis. 

Judgements
The following are the critical judgements, 
apart from those involving estimates (which are 
dealt with separately below), that the Directors 
have made in the process of applying the 
Group’s accounting policies that have the most 
significant effect on the amounts recognised in 
the Group’s financial statements. 

These are as follows:

 › Assessment of cloud-based software costs 
in relation to the Group’s cloud hosted 
ERP system.

 › Determining the treatment of payment to 
customers in significant contracts. This is 
considered a critical judgement, but the 
impact is immaterial for the current year.

 ›

Identification and presentation of  
non-underlying items (note 5).

 › Assessment of the Infringement Decision 
announced by the UK’s Competition and 
Markets Authority (‘CMA’) (note 20).

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2. Summary of significant accounting 
policies continued
2.3 Judgements and estimates continued
Intangible assets – cloud-based 
software costs 
The determination of whether a cloud-based 
software arrangement represents a pure 
Software as a Service solution, or a right to 
take possession of, and to use, the software 
requires judgement. 

In light of the recent IFRIC agenda decision 
regarding cloud-based software, the Group 
has reviewed its service agreements in 
respect of its cloud-based ERP system and 
has considered several factors to conclude 
on the appropriate accounting treatment. 
These factors include the nature and key 
terms of licence arrangements, ownership 
of intellectual property rights, ability to 
restrict access to systems and the feasibility 
of removing software applications from the 
cloud environment and running them within 
the Group’s own IT environment instead, 
taking into account the associated costs and 
potential change in functionality. 

Having considered these factors the Group 
concluded that it does have substantive 
control over the ERP system and has therefore 
recognised it as an intangible asset in line 
with the guidance under IAS 38. Had the 
Group concluded that it does not have control, 
a proportion of the costs would have been 
expensed in the Income Statement in the 
current year.

Identification and presentation of  
non-underlying items

In 2020 the Group updated its classification 
policy for non-underlying items (note 5). 
Following the update all amortisation and 
impairment charges for acquired intangible 
assets are included as non-underlying items, 
in line with the majority of peer companies 
of the Group. Significant restructuring 
costs (for example, relating to office or 
business closures), the CMA provision and 
the revaluation of deferred tax balances 
following substantial tax legislation changes 
are also included as non-underlying items.

The Directors believe that this classification 
of underlying and non-underlying items, 
when considered together with total statutory 
results, provides investors, analysts and other 
stakeholders with helpful complementary 
information to understand better the 
financial performance and position of the 
Group from period to period, and allows 
the Group’s performance to be more 
easily compared against the majority of 
its peer companies. These measures are 
also used by management for planning 
and reporting purposes. They may not be 
directly comparable with similarly described 
measures used by other companies.

Estimates
IAS 1 requires the disclosure of assumptions 
and estimates at the end of the current 
reporting period that have a significant risk 
of resulting in a material adjustment to the 
carrying amounts of assets and liabilities 
within the next financial year.

Transaction price
The transaction price for each performance 
obligation comprises the stand-alone selling 
price for the product excluding value-
added tax and net of rebates and discounts. 
Intra-Group sales are eliminated in the 
consolidated financial statements.

The Directors consider these estimates to be 
as follows: 

 › Key assumptions used in discounted cash 
flow projections for impairment testing of 
certain intangible assets (note 11).

2.4 Revenue recognition
Identification of performance 
obligations
Revenue comprises consideration received 
or receivable for the sale of goods in the 
ordinary course of the Group’s activities, 
namely the distribution of pharmaceutical 
products. The Group has assessed the 
performance obligations as being each unit 
of good sold by the Group. 

The Group receives royalties in relation 
to certain agreements with distributors in 
exchange for the licensed use of intellectual 
property and trademarks owned by the 
Group, which are generally based on 
sales volumes. The Group also receives 
product margin generated by third parties 
on its behalf under certain transitional 
arrangements. The Group has assessed the 
performance obligations as being each unit 
of good sold by the third parties. 

Royalty income and the deductions relating 
to rebates and discounts are based on the 
Group’s contractual obligations. Certain 
of the rebate arrangements also include 
elements of variable consideration. The 
Group does not consider these elements to be 
significant, however an estimate of variable 
consideration is included where appropriate. 
The IFRS 15 exemption from estimating 
variable consideration has been applied to 
the Group’s sales-based royalties.

The Group has considered whether it is an 
‘agent’ or ‘principal’ under IFRS 15 for each 
commercial arrangement and accounted for 
these accordingly. The Group is considered 
the ‘principal’ for all key commercial 
relationships relating to sale of goods, 
except the relationship with certain supply 
partners as described in full under ‘Specific 
revenue streams’. This is because the Group 
controls each specified good before transfer 
to customers.

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2. Summary of significant  
accounting policies continued
2.4 Revenue recognition continued
Where consideration is payable to a customer, 
this is evaluated by the Group to determine 
whether the amount represents a reduction of 
the transaction price, a payment for distinct 
goods or services or a combination of the 
two. The fair value of the good or service is 
also evaluated to assess whether the payment 
should be accounted for as a payment to 
suppliers or a reduction in transaction price.

Timing of recognition
Under IFRS 15 an entity recognises revenue 
when it satisfies a performance obligation by 
transferring a good to a customer. An entity 
transfers a good to a customer when the 
customer obtains control of that good. Control 
may be transferred either at a point in time or 
over time. For the Group, revenue is recognised 
at a point in time when customers have control 
of the sold goods, or on an appropriate basis 
where royalty or other arrangements are in 
place with third parties. To determine the point 
in time control is transferred for sale of goods 
the Group considers all relevant indicators. 
Revenue is recognised net of a provision for 
the expected level of returns.

Specific revenue streams
The Group has the following recognition 
policies for different commercial arrangements: 

(i)   Pharmaceutical product sales – ex-works 
terms: Recognition at a point in time when 
each unit of pharmaceutical product is 
available to the customer for collection. 
At this point in time the customer has an 
obligation to pay for the goods, legal 
title and significant risks and rewards 
of ownership.

(ii)   Pharmaceutical product sales – dispatch 
terms and delivery at place: Recognition 
at a point in time when each unit of 
pharmaceutical product is dispatched to 
the customer or reaches the designated 
place. At this point in time the customer 
has an obligation to pay for the goods, 
legal title and significant risks and 
rewards of ownership. This revenue 
recognition policy covers the cross border 
e-commerce stream as referred to in the 
strategic report. 

(iii)  Pharmaceutical product royalties 
receivable: Recognition at a point 
in time when the third party makes 
pharmaceutical product sales subject to 
a royalty agreement with the Group. 

(iv)  Pharmaceutical product rebates, discounts 
and payments to customers: Recognition 
as a deduction from revenue when the 
third party makes pharmaceutical product 
sales subject to a rebate agreement with 
the Group or when sales are made in the 
scope of the VPAS Voluntary Scheme. 

 VPAS applies to branded, licensed 
medicines which are available on NHS 
prescription. Under the scheme, a fixed 
percentage of measured sales is due to 
the Department of Health and Social Care 
and the rebate is calculated and paid 
on a quarterly basis. For medium-sized 
companies, the VPAS scheme includes an 
exemption where total measured sales are 
less than £5.0m per year. As the Group’s 
total measured sales in 2021 were under 
this threshold, the Group was exempt from 
any VPAS payments and, as a result, no 
amounts were deducted from revenue 
(2020: no deduction).

 For transactions with variable consideration, 
such as coupons, this is recognised at the 
point of sale to the customer. 

 Payments to customers are accounted for as 
a reduction of revenue unless they are linked 
to a distinct service, in which case they are 
classified as an operating expense. 

(v)   Pharmaceutical product transitional 
agreements: Recognition of a point 
in time when the third party makes 
pharmaceutical product sales subject to a 
transitional agreement with the Group. 

 The amounts recognised in statutory revenue 
represent the product margin generated 
by the third party on behalf of the Group. 
Related transitional agreement fees are 
recognised within administrative expenses. 

 This is relevant to Nizoral (note 34) where 
the Group has transitional agreements with 
certain supply partners. Under the terms 
of the agreements, the Group receives 
the benefit of the net profit on sales of 
Nizoral from the date of acquisition up 
until the product licences in the Asia-Pacific 
territories transfer to Alliance. The Group 
has determined it is an ‘agent’ in these 
relationships as it does not control the sale 
of goods to third party customers. 

The Group does not consider that judgements 
made in evaluating when customers 
obtain control of a promised good to have 
significantly influenced the timing of revenue 
recognition in the year.

2.5 Foreign currency
The consolidated financial statements 
are presented in Sterling, which is the 
presentational currency of the Group and the 
functional currency of the Company. Foreign 
currency transactions by Group companies 
are booked at the exchange rate ruling on 
the date of the transaction. Foreign currency 
monetary assets and liabilities are retranslated 
into Sterling at the rate of exchange ruling at 
the balance sheet date. Foreign exchange 
differences arising on translation are 
recognised in the Income Statement except 
for differences arising on the retranslation of 
a financial liability designated as a hedge 
of the net investment in a foreign operation 
that is effective, or qualifying cash flow 
hedges, which are recognised directly in other 
comprehensive income.

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2. Summary of significant accounting 
policies continued
2.5 Foreign currency continued
The assets and liabilities of foreign 
operations, including goodwill and fair 
value adjustments arising on consolidation, 
are translated to the Group’s presentational 
currency, Sterling, at foreign exchange rates 
ruling at the balance sheet date. The revenues 
and expenses of foreign operations are 
translated at an average rate for the year 
where this rate approximates to the foreign 
exchange rates ruling at the dates of the 
transactions. Exchange differences arising 
from translation of foreign operations are 
reported in other comprehensive income 
and accumulated in the translation reserve. 
Foreign currency differences arising on the 
retranslation of a hedge of a net investment 
in a foreign operation are reported in other 
comprehensive income and accumulated in 
the translation reserve, to the extent that the 
hedge is effective.

2.6 Operating segments
Operating segments are reported in a 
manner consistent with the internal reporting 
provided to the Group’s Chief Operating 
Decision Maker (‘CODM’). The Group’s 
Board of Directors (‘the Board’) is the Group’s 
Chief Operating Decision Maker (‘CODM’), 
as defined by IFRS 8, and all significant 
operating decisions are taken by the Board. 

2.7 Property, plant and equipment
Computer equipment, fixtures, fittings and 
equipment, plant and machinery and motor 
vehicles are stated at the cost of purchase 
less any provisions for depreciation and 
impairment. Depreciation of an asset starts 
when the asset is available for use. The rates 
generally applicable are:

Computer equipment  
20% – 33.3% per annum, straight line

Fixtures, fittings and equipment  
20% – 25% per annum, straight line

Plant and machinery  
20% – 25% per annum, straight line

2.8 Leases
At inception of a contract, the Group assesses 
whether a contract is, or contains, a lease. 
A contract is, or contains, a lease if the 
contract conveys the right to control the use 
of an identified asset for a period of time in 
exchange for consideration. 

Leases are recognised as a right-of-use asset 
and a corresponding liability at the date at 
which the leased asset is available for use by 
the Group. Each lease payment is allocated 
between the liability and finance cost. The 
finance cost is charged to profit or loss over 
the lease period so as to produce a constant 
periodic rate of interest on the remaining 
balance of the liability for each period.  

The right-of-use asset is depreciated over the 
shorter of the asset’s useful life and the lease 
term on a straight-line basis.

Assets and liabilities arising from a lease are 
initially measured on a present value basis. 
The lease payments are discounted using the 
Group’s incremental borrowing rate.

Payments associated with short-term leases 
and leases of low-value assets are recognised 
on a straight-line basis as an expense in the 
Income Statement. Short-term leases are 
leases with a lease term of 12 months or less. 
Low-value assets comprise IT equipment.

2.9 Intangible assets and goodwill
Goodwill
Goodwill is stated at cost less any accumulated 
impairment losses. Goodwill is allocated to 
cash-generating units and is not amortised but 
is tested annually for impairment. 

Acquired intangible assets
(i)  Brands
Separately acquired brands are shown at 
cost less accumulated amortisation and 
impairment. Brands acquired as part of a 
business combination are recognised at fair 
value at the acquisition date, where they are 
separately identifiable. Brands are amortised 
over their useful economic life, except when 
their life is determined as being indefinite.

Applying indefinite lives to certain acquired 
brands is appropriate due to the stable long-
term nature of the business and the enduring 
nature of the brands. Indefinite life brands are 
tested at least annually for impairment.

A review of the useful economic life of 
brands is performed annually, to ensure that 
these lives are still appropriate. If a brand is 
considered to have a finite life, its carrying 
value is amortised over that period.

(ii)  Patents
Where an acquired intangible asset includes 
a definite period of patent protection and the 
value attributed to the patent is considered 
material, the Group has accounted for the 
value of the patent separate to the underlying 
brand. The patent is amortised over the 
period to patent expiry.

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2. Summary of significant accounting 
policies continued
2.9 Intangible assets and goodwill 
continued
(iii)  Distribution rights
Payments made in respect of product 
registration and distribution rights are 
capitalised where the rights comply with 
the above requirements for recognition 
of acquired brands. If the registration or 
distribution rights are for a defined time 
period, the intangible asset is amortised over 
that period. If no time period is defined, the 
intangible asset is treated in the same way 
as acquired brands with an indefinite life. 
If the licence period can be extended the 
useful life of the intangible asset shall include 
the renewal period only if there is evidence 
to support renewal by the entity without 
disproportionate cost.

(iv) Computer software
Computer software comprises software 
purchased from third parties as well as 
the cost of internally developed software. 
Computer software licences are capitalised 
on the basis of the costs incurred to acquire 
and bring into use the specific software. 
Costs that are directly associated with 
the production of identifiable and unique 
software products controlled by the Group, 
and are probable of producing future 
economic benefits, are recognised as 
intangible assets. Direct costs of software 

development include employee costs and 
directly attributable overheads. Software 
integral to an item of hardware equipment is 
classified as property, plant and equipment. 
Costs associated with maintaining software 
programs are recognised as an expense 
when they are incurred. Amortisation is 
charged to the Income Statement on a 
straight-line basis over the estimated useful 
life from the date the software is available 
for use, generally eight years. In bringing the 
asset into use, the Directors have determined 
that the asset related to the ERP system should 
be reclassified from property, plant and 
equipment to intangible assets. The Directors 
have considered the impact on the prior 
period and have considered this not material.

Development costs
Research expenditure is charged to the Income 
Statement in the period in which it is incurred. 
Development expenditure is capitalised when 
it can be reliably measured and the project 
it is attributable to is separately identifiable, 
technically feasible, demonstrates future 
economic benefit, and will be used or sold by 
the Group once completed. 

The capitalised cost is amortised over the period 
during which the Group is expected to benefit 
and begins when the asset is ready for use. 

Development costs are reviewed at least 
annually for impairment by assessing the 
recoverable amount of each cash-generating 
unit, to which the development costs relate. 

The recoverable amount is the higher of 
fair value less costs to sell and value in 
use. Development costs not meeting the 
recognition criteria are expensed as incurred.

Impairment
The carrying amounts of the Group’s non-
financial assets are reviewed at each 
reporting date to determine whether there is 
any indication of impairment. For intangible 
assets with an indefinite life, assets with a 
finite life that show indicators of impairment, 
and goodwill this includes estimation of the 
recoverable amount.

The recoverable amount of an asset or cash-
generating unit is the greater of its value in use 
and its fair value less costs to sell. In assessing 
value in use, the estimated future cash flows 
are discounted to their present value using 
a discount rate that reflects current market 
assessments of the time value of money 
and the risks specific to the asset. For the 
purpose of impairment testing, assets that 
cannot be tested individually are grouped 
together into the smallest group of assets 
that generates cash inflows from continuing 
use that are largely independent of the cash 
inflows of other assets or groups of assets (the 
‘cash-generating unit’). The Directors have 
determined that the cash-generating units are 
at product-group level.

The goodwill acquired in a business 
combination, for the purpose of impairment 
testing, is allocated to cash-generating units, 
or (‘CGU’). For the purposes of goodwill 
impairment testing, CGUs to which goodwill 
has been allocated are aggregated so that the 
level at which impairment is tested reflects the 
lowest level at which goodwill is monitored for 
internal reporting purposes. Goodwill acquired 
in a business combination is allocated to groups 
of CGUs that are expected to benefit from the 
synergies of the combination.

An impairment loss is recognised if the 
carrying amount of an asset or its CGU 
exceeds its estimated recoverable amount. 
Impairment losses are recognised in profit or 
loss. Impairment losses recognised in respect 
of CGUs are allocated first to reduce the 
carrying amount of any goodwill allocated 
to the units, and then to reduce the carrying 
amounts of the other assets in the unit (group 
of units) on a pro rata basis.

An impairment loss in respect of goodwill is not 
reversed. In respect of other assets, impairment 
losses recognised in prior periods are assessed 
at each reporting date for any indications that 
the loss has decreased or no longer exists. 
An impairment loss is reversed only to the 
extent that the asset’s carrying amount does 
not exceed the carrying amount that would 
have been determined, net of depreciation 
or amortisation, if no impairment loss had 
been recognised.

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2. Summary of significant accounting 
policies continued 
2.10 Inventories
Inventories are included at the lower of 
cost, less any provision for impairment, or 
net realisable value. Except for the Biogix 
entity, which recognises inventory on an 
average cost basis, inventory cost for the 
Group is determined on a first-in-first-out 
basis. Inventory provisions have been made 
for slow-moving and obsolete stock. These 
provisions are estimates and the actual costs 
and timing of future cash flows are dependent 
on future events. The difference between 
expectations and the actual future liability 
will be accounted for in the period when such 
determination is made.

2.11 Taxation
Tax on the profit or loss for the year comprises 
current and deferred tax. Tax is recognised in 
the Income Statement except to the extent that 
it relates to items recognised directly in equity, 
in which case it is recognised in equity.

Current tax is the expected tax payable or 
receivable on the taxable income or loss 
for the year, using tax rates enacted or 
substantively enacted at the balance sheet 
date, and any adjustment to tax payable in 
respect of previous years.

Deferred tax is provided on temporary 
differences between the carrying amounts 
of assets and liabilities for financial 
reporting purposes and the amounts 
used for taxation purposes. The following 
temporary differences are not provided 
for: the initial recognition of goodwill; the 
initial recognition of assets or liabilities that 
affect neither accounting nor taxable profit 
other than in a business combination; and 
differences relating to investment and loans 
to subsidiaries to the extent that they will 
probably not reverse in the foreseeable 
future. The amount of deferred tax provided is 
based on the expected manner of realisation 
or settlement of the carrying amount of 
assets and liabilities, using tax rates enacted 
or substantively enacted at the balance 
sheet date.

A deferred tax asset is recognised only to the 
extent that it is probable that future taxable 
profits will be available against which the 
temporary difference can be utilised. 

2.12 Derivative financial instruments 
and hedging activities
The Group holds derivative financial 
instruments to hedge its foreign currency risk 
exposures. Derivatives are initially measured 
at fair value. Subsequent to initial recognition, 
derivatives are measured at fair value, and 
changes therein are recognised in profit or 
loss unless designated as cash flow hedges.

The Group designates certain derivatives as 
hedging instruments to hedge the variability 
in cash flows associated with highly probable 
forecast transactions arising from changes in 
foreign exchange rates. 

At inception of designated hedging 
relationships, the Group documents the 
risk management objective and strategy 
for undertaking the hedge. The Group 
also documents the economic relationship 
between the hedged item and the hedging 
instrument, including whether the changes in 
cash flows of the hedged item and hedging 
instrument are expected to offset each other.

Cash flow hedges
When a derivative is designated as a cash 
flow hedging instrument, the effective portion 
of changes in the fair value of the derivative 
is recognised in other comprehensive income 
and accumulated in the cash flow hedging 
reserve. The effective portion of changes in the 
fair value of the derivative that is recognised in 
other comprehensive income is limited to the 
cumulative change in fair value of the hedged 
item, determined on a present value basis, from 
inception of the hedge. Any ineffective portion 
of changes in the fair value of the derivative is 
recognised immediately in profit or loss.

If the hedge no longer meets the criteria for 
hedge accounting or the hedging instrument is 
sold, expires, is terminated or is exercised, then 
hedge accounting is discontinued prospectively.  

When hedge accounting for cash flow 
hedges is discontinued, the amount that has 
been accumulated in the cash flow hedging 
reserve remains in equity until it is reclassified 
to profit or loss in the same period or periods 
as the hedged expected future cash flows 
affect profit or loss. 

If the hedged future cash flows are no longer 
expected to occur, then the amounts that have 
been accumulated in the cash flow hedging 
reserve and the cost of hedging reserve are 
immediately reclassified to profit or loss.

Translation risk
Exchange differences arising from 
the translation of the net investment in 
foreign operations are reported in other 
comprehensive income and accumulated 
in the translation reserve. Gains and losses 
on those hedging instruments designated 
as hedges of the net investment in foreign 
operations, are recognised to the extent that 
the hedging relationship is effective; these 
amounts are included in exchange differences 
on translation of foreign operations as stated in 
the statement of comprehensive income. Gains 
and losses relating to hedge ineffectiveness 
are recognised immediately in the Income 
Statement for the period. Gains and losses 
accumulated in the translation reserve are 
reclassified to the Income Statement when the 
foreign investment is disposed of.

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2. Summary of significant accounting 
policies continued
2.13 Non-derivative financial 
instruments
Non-derivative financial instruments comprise 
investments in equity and debt securities, 
trade and other receivables, cash and cash 
equivalents, loans and borrowings, and trade 
and other payables.

Modifications of financial instruments 
(including loans and borrowings) are 
reviewed quantitatively and qualitatively to 
determine if the modification is ‘substantial’. 
Substantial modification of a financial 
liability results in derecognition of the original 
balance, and recognition of a new financial 
liability at fair value. The difference between 
the carrying amount of the original financial 
liability and the fair value of the new financial 
liability is charged to the Income Statement. 
A non-substantial modification of financial 
liability does not result in the derecognition 
of the original balance, however it may also 
result in a gain or loss recognised in the 
income statement.

Trade and other receivables
Trade and other receivables are recognised 
initially at fair value. Subsequent to initial 
recognition they are measured at amortised 
cost using the effective interest method, less 
any impairment losses. The Group’s trade 
receivables are subject to the IFRS 9 expected 
credit loss model. The Group has applied the 

simplified approach to measuring expected 
credit losses which uses a lifetime expected 
loss allowance based on historic default rates. 
The expected credit loss rate varies depending 
on whether and the extent to which settlement 
of the trade receivables is overdue.

Accrued income represents amounts owed 
unconditionally to the Group which have 
not been invoiced at the year end. For these 
assets, only the passage of time is required 
before payment becomes due.

Trade and other payables
Trade and other payables are recognised 
initially at fair value. Subsequent to initial 
recognition they are measured at amortised 
cost using the effective interest method.

Cash and cash equivalents
Cash and cash equivalents comprise cash 
balances and call deposits. Bank overdrafts 
that are repayable on demand and form an 
integral part of the Group’s cash management 
are included as a component of cash and 
cash equivalents for the purpose only of the 
cash flow statement. Dividends and interest 
received are included in investing activities. 
Dividends and interest paid are included in 
financing activities.

Investments in debt and equity securities
The Company’s investment and loans to 
subsidiaries is stated at amortised cost 
less impairment.

Interest-bearing borrowings
Interest-bearing borrowings are recognised 
initially at fair value less attributable 
transaction costs. Subsequent to initial 
recognition, interest-bearing borrowings are 
stated at amortised cost using the effective 
interest method. 

2.14 Employee benefits – Share-based 
payment transactions
Employees (including Executive Directors) of 
the Group receive part of their remuneration 
in the form of share-based payments, 
whereby, depending on the scheme, 
employees render services in exchange 
for rights over shares (‘equity-settled 
transactions’) or entitlement to a future cash 
payment (‘cash-settled transactions’), the 
amount of which is determined with reference 
to the Company’s share price. 

The cost of equity-settled transactions with 
employees is measured, where appropriate, 
with reference to the fair value at the date 
on which they are granted. Where options 
need to be valued an appropriate valuation 
model is applied. The expected life used 
in the model has been adjusted, based on 
management’s best estimate, for the effects 
of exercise restrictions and behavioural 
considerations. The cost of equity-settled 
transactions is fully recharged to subsidiaries.

The cost of cash-settled transactions is 
measured with reference to the fair value of 
the liability, which is taken to be the closing 
price of the Company’s shares. Until the 
liability is settled it is remeasured at the end 
of each reporting period and at the date of 
settlement, with any changes in the fair value 
being recognised in the Income Statement.

The cost of equity-settled transactions is 
recognised, along with a corresponding 
increase in equity, over the years in which the 
performance conditions are fulfilled, ending 
on the date on which the relevant employees 
become fully entitled to the award (‘vesting 
date’). The cost of cash-settled transactions 
is recognised, along with a provision 
for expected cash settlement, over the 
vesting period.

At each reporting date, the cumulative 
expense recognised for equity-settled 
transactions reflects the extent to which the 
vesting period has expired and the number of 
awards that, in the opinion of management, 
will ultimately vest. Management’s estimates 
are based on the best available information 
at that date. No expense is recognised for 
awards that do not ultimately vest, except for 
awards where vesting is conditional upon a 
market condition, which are treated as vesting 
irrespective of whether or not the market 
condition is satisfied, provided that all other 
performance conditions are satisfied.

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2. Summary of significant accounting 
policies continued
2.15 Equity
The provision of shares to satisfy certain of 
the Group’s share option schemes can be 
facilitated by purchases of own shares by 
the Group’s Employee Benefit Trust. The costs 
of operating the Trust is borne by the Group 
but is not material. To date, no shares have 
been purchased by the Trust for satisfaction of 
outstanding or future share option awards.

The Employee Benefit Trust is considered to 
be controlled by the Group. The activities 
of the Trust are conducted on behalf of the 
Group according to its specific business 
needs in order to obtain benefits from its 
operation and, on this basis, the assets held 
by the Trust are consolidated into the Group’s 
financial statements.

‘Share capital’ represents the nominal value 
of equity shares.

‘Share premium’ represents the excess over 
nominal value of the fair value of consideration 
received for equity shares, net of expenses of 
the share issue.

‘Share option reserve’ represents equity-
settled share-based employee remuneration.

‘Retained earnings’ represents retained profit.

‘Other reserve’ represents the difference 
between the fair value and nominal value of 
shares issued on a reverse takeover.

‘Cash flow hedging reserve’ represents the 
fair value of derivative financial instruments 
at the balance sheet date that are designated 
as cash flow hedges, net of deferred tax, 
less amounts reclassified through other 
comprehensive income.

‘Translation reserve’ represents gains and 
losses arising on translation of the net assets 
of overseas operations into the Group’s 
presentation currency of Sterling.

2.16 Provisions
Provisions are recognised when there is a 
present legal or constructive obligation as a 
result of a past event, for which it is probable 
that a transfer of economic benefits will be 
required for settlement and where a reliable 
estimate can be made of the amount of 
the obligation. Where material, provisions 
have been discounted to their present value.

2.17 Business combinations
Business combinations are accounted for using 
the acquisition accounting method. Identifiable 
assets and liabilities acquired are measured 
at fair value at acquisition date. Costs related 
to the acquisition, other than those associated 
with the issue of debt or equity securities, 
are expensed as incurred. Any contingent 
consideration payable is recognised  
at fair value at the acquisition date.  

If the contingent consideration is classified 
as equity, it is not remeasured and settlement 
is accounted for within equity. Otherwise, 
subsequent changes to the fair value of the 
contingent consideration are recognised in profit 
or loss. The Group also engages in acquisitions 
of product-specific assets (such as brands – 
set out in note 2.9). Where elements of the 
consideration paid are variable and based on 
future revenues, the cost of the intangible asset 
recognised is based on the agreed minimum 
payments and any additional payments are 
expensed as the related sales occur.

2.18 Going concern
The Group is in a net current asset position of 
£40.4m (2020: £47.1m). The Group’s debt 
funding is provided by a £165m Revolving 
Credit Facility (‘RCF’), together with a £50m 
accordion facility, with a syndicate of lenders. 
This facility is available until July 2024. 

The Directors have prepared cash flow forecasts 
for a period of more than 12 months from the 
date of approval of these financial statements 
(the going concern period). These indicate that 
the Group will have sufficient funds, given the 
RCF financing available, to meet its liabilities as 
they fall due for that period. 

Also, the Directors have considered the 
sensitivity of cash flow forecasts to severe 
downside scenarios, including the potential 
impact of the timing of the payment in relation 
to the CMA decision, detailed further in note 20.  

The Directors considered a reverse stress test 
scenario which indicates that a decline in 
EBITDA against forecast of over 40% would 
be needed to result in a breach of loan 
covenants. The Directors consider this remote.

The RCF is drawn in short to medium-term 
tranches of debt which are repayable within 
12 months of draw-down. These tranches 
of debt can be rolled over provided certain 
conditions are met, including covenant 
compliance. The Group considers that 
it is highly unlikely it would be unable to 
exercise its right to roll-over the debt based 
on the forecast covenant compliance in the 
severe downside modelled above. There 
are mitigating actions (within the control 
of the Group) it could take to maintain 
compliance with these conditions, including 
future covenant requirements. The Directors 
therefore believe that the Group has the 
ability and the intent to roll-over the drawn 
RCF amounts when due and consequently has 
presented the RCF as a non-current liability. 

Consequently, the Directors are confident 
that the Company will have sufficient funds 
to continue to meet its liabilities as they fall 
due for at least 12 months from the date of 
approval of the financial statements and 
have therefore determined it is appropriate to 
adopt the going concern basis in preparing 
the financial statements. 

109

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2. Summary of significant accounting policies continued
2.19 Alternative performance measures
The performance of the Group is assessed using Alternative Performance Measures (‘APMs’). 
The Group’s results are presented both before and after non-underlying items. Adjusted 
profitability measures are presented excluding non-underlying items as we believe this 
provides both management and investors with useful additional information about the Group’s 
performance and aids effective comparison of the Group’s trading performance from one 
period to the next and with similar businesses. 

In addition, the Group’s results are described using certain other measures that are not 
defined under IFRS and are therefore considered to be APMs. These measures are used by 
management to monitor ongoing business performance against both shorter-term budgets 
and forecasts but also against the Group’s longer-term strategic plans. APMs are presented 
in note 34.

The Group does not consider adjusted profitability measures or APMs to be a substitute for, or 
superior to, IFRS measures.

3. Revenue and segmental information 
The Group’s reportable segments are the strategic business units that represent different 
parts of the overall product portfolio, these being Consumer Healthcare brands and 
Prescription Medicines. The business units are managed separately as each portfolio 
requires different expertise to deliver the corresponding product offering as a result of the 
inherently different characteristics of these product types.

Operating segments reflect the way in which information is presented to and reviewed 
by the CODM for the purposes of making strategic decisions and assessing Group-wide 
performance. The Group’s Board of Directors (‘the Board’) is the Group’s CODM. The Group 
evaluates performance of the operational segments on the basis of revenue and gross 
profit. Other than intangible assets, disclosed in note 11, assets and liabilities are reported 
to the Board at Group level and are not separated segmentally.

Revenue

Revenue information by brand

Consumer Healthcare brands:

Kelo-cote

Amberen

Nizoral*

MacuShield

Aloclair

Vamousse

Other Consumer Healthcare brands

Total revenue – Consumer Healthcare brands:

Prescription Medicines:

Hydromol

Flamma Franchise

Forceval

Other prescription medicines

Total revenue – Prescription Medicines

Total revenue 

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

48,845

19,233

14,189

8,829

5,773

4,110

14,397

115,376

7,009

6,610

5,685

28,527

47,831

163,207

34,748

–

13,260

6,751

7,601

5,626

17,354

85,340

6,304

5,897

4,893

27,367

44,461

129,801

* 

 Nizoral statutory revenue includes revenue generated on an agency basis. Nizoral revenue presented on a see-through Income Statement basis is 
included as an alternative performance measure in note 34.

110

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3. Revenue and segmental information continued
Revenue information by geography
Classification by geography is based on customer location. 

Major customers 
The revenues from the Group’s largest customers are as follows. No customers separately 
comprised 10% or more of revenue (2020: two). Major customer 1 is a multinational 
organisation with sales in both EMEA and AMER regions. 

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

Europe, Middle East and Africa (EMEA)

Asia Pacific and China (APAC) 

Americas (AMER)

Total revenue

Operating segment results

 89,188 

 48,030 

 25,989 

163,207

Revenue 

Cost of sales 

Gross profit

Revenue 

Cost of sales 

Gross profit

Year ended 31 December 2021

Consumer Healthcare 
£000s

Prescription Medicines
£000s 

115,376

(31,545)

83,831

47,831

(22,212)

25,619

Year ended 31 December 2020 

Consumer Healthcare 
£000s

Prescription Medicines
£000s 

85,340

(26,199)

59,141

44,461

(20,786)

23,675

 93,769 

 29,309 

 6,723 

129,801

Total 
£000s 

163,207

(53,757)

109,450

Total 
£000s 

129,801

(46,985)

82,816

Major customer 1 (Consumer Healthcare and Prescription 
Medicines sales in EMEA and AMER)

Major customer 2 (Consumer Healthcare sales in EMEA)

4. Profit before taxation

Profit before taxation is stated after charging/(crediting):

Amounts receivable by the Company’s auditor and its  
associates in respect of:

– The audit of these financial statements

– The audit of the financial statements of subsidiaries

– Other assurance services

Amortisation of intangible assets

Impairment of intangible assets

CMA provision

Losses on disposals

Share options charge 

Depreciation of plant, property and equipment

(Gain)/loss on foreign exchange transactions

Year ended
31 December 2021
£000s

Year ended
31 December 2020
£000s

13,723

12,014

17,345

16,646

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

96

326

5

8,530

6,150

7,900

–

2,250

1,575

(205)

48

198

5

7,155

12,057

–

308

1,374

1,753

653

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5. Non-underlying items
The Group presents a number of non-IFRS measures which exclude the impact of 
significant non-underlying items. This is to allow investors to understand the underlying 
trading performance of the Group, and can exclude items such as: amortisation and 
impairment of acquired intangible assets; restructuring costs; significant gains or losses on 
disposal; remeasurement and accounting for the passage of time in respect of contingent 
considerations; and the revaluation of deferred tax balances following substantial tax 
legislation changes. This assessment requires judgement to be applied by the Directors 
as to which transactions are non-underlying and whether this classification enhances the 
understanding of the users of the financial statements.

Amortisation of acquired intangible assets

Impairment of goodwill and intangible assets

Biogix acquisition costs

CMA provision

Restructuring costs

Other

Total non-underlying items before taxation

Taxation on non-underlying items

Impact of UK tax rate change from 17% to 19%

Impact of UK tax rate change from 19% to 25%

Non-underlying taxation

Total non-underlying items after taxation

Year ended 
31 December 2021
 £000s

Year ended 
31 December 2020
 £000s

(7,168)

(6,150)

–

(7,900)

(2,420)

(423)

(24,061)

2,167

–

(4,972)

(2,805)

(26,866)

(7,155)

(12,057)

(1,300)

–

–

–

(20,512)

3,194

(1,811)

–

1,383

(19,129)

Amortisation of intangible assets
The amortisation costs of acquired intangible assets are a significant item considered 
unrelated to trading performance, and as such have been presented as non-underlying. This 
classification is in line with the majority of peer companies of the Group. 

Impairment of goodwill and intangible assets
The impairment reviews for the Group’s intangible assets resulted in impairment losses as the 
carrying value of certain cash-generating units exceeded estimated recoverable amounts. 
Further details are provided in note 11. The impairment losses are significant items resulting 
from changes in assumptions for future recoverable amounts. As such they are considered 
unrelated to 2021 trading performance, and have been presented as non-underlying.

Biogix acquisition costs
Legal and professional fees related to the purchase of Biogix Inc in 2020 (note 31) were 
£1.3m. These acquisition costs are a significant item considered unrelated to 2020 trading 
performance, and as such have been presented as non-underlying. 

CMA provision
The CMA provision of £7.9m relates to the CMA Infringement Decision which is detailed 
further in note 20. This is considered unrelated to trading performance, and as such has been 
presented as non-underlying.

Restructuring costs
Costs of Group restructuring in the year ended 31 December 2021 relating to the closure of 
the Milan and Los Angeles offices were £2.4m (2020: £Nil). These costs are a significant  
item considered unrelated to 2021 trading performance, and as such have been presented  
as non-underlying. 

Impact of UK tax rate change from 17% to 19% 
The taxation charge for the year ended 31 December 2020 includes the impact on deferred 
tax of the main rate of UK corporation tax from 17% to 19%, following the abandonment 
of the proposed reduction to 17% in the March 2020 Budget. The change in tax rate is a 
significant item that relates only to deferred tax, principally on intangibles, and is unrelated to 
trading performance. As such, the rate change impact has been presented as non-underlying.

Impact of UK tax rate change from 19% to 25% 
In the Budget on 3 March 2021, a further change to UK corporation tax rates was 
announced, increasing the main rate from 19% to 25% with effect from 1 April 2023.  
The impact on deferred tax of this further rate increase is included in these financial  
statements as a non-underlying item.

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6. Finance costs

Interest payable and similar charges

On loans and overdrafts

Amortised finance issue costs 

Interest on lease liabilities

Finance income

Interest income

Net exchange gains/(losses)

Finance costs – net

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

(2,904)

(639)

(103)

(3,646)

23

205

228

(3,418)

(1,988)

(581)

(88)

(2,657)

10

(653)

(643)

(3,300)

7. Directors and employees
Employee benefit expenses for the Group (including Executive Directors) during the year were  
as follows:

Key management of the Group is the Board of Directors (including Non-executive Directors) 
and the Senior Leadership Team (SLT). Benefit expenses in respect of the key management 
were as follows:

Key management remuneration

Pension contributions

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

3,442

121

3,563

2,380

112

2,492

During the year contributions were paid to defined contribution schemes for two Executive 
Directors (2020: two).

Gain on share options exercised by Executive Directors during the year was £363,000 
(2020: £54,000). The notional non-cash IFRS 2 share-based payment expense in respect  
of Directors was £256,000 (2020: £217,000).

The amounts set out above include remuneration in respect of the highest paid Director  
as follows:

Wages and salaries

Social security costs

Other pension costs (note 28)

Share-based employee remuneration (note 24)

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

18,886

2,077

1,306

2,250

24,519

16,437

1,958

994

1,374

20,763

Emoluments for qualifying services

Pension contributions

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

587

29

616

531

27

558

The average number of employees of the Group (including Directors) during the year was:

Management and administration

Year ended 
31 December 2021
Number

Year ended 
31 December 2020
Number

255

221

The notional non-cash IFRS 2 share-based payment expense in respect of the highest paid 
Director was £177,000 (2020: £156,000).

Average number of members of the Board of Directors (including Non-executive Directors) for 
the year ended 31 December 2021 was six (2020: six).

113

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8. Taxation
Analysis of the charge for the period is as follows:

Corporation tax 

In respect of current period

Adjustment in respect of prior periods

Deferred tax (see note 22)

Origination and reversal of temporary differences

Adjustment in respect of prior periods

Taxation

Year ended
 31 December 2021
£000s

Year ended
 31 December 2020
£000s

6,069

(65)

6,004

4,471

363

10,838

4,417

(123)

4,294

705

(10)

4,989

The difference between the total tax charge shown above and the amount calculated by 
applying the standard rate of UK corporation tax to the profit before tax is as follows:

Year ended
 31 December 2021
£000s

Year ended
 31 December 2020
£000s

Profit before taxation

Profit before taxation multiplied by standard rate of corporation 
tax in the United Kingdom of 19.00% (2019: 19.00%)

Effect of:

Non-deductible expenses

Non-taxable income

Adjustment in respect of prior periods

Differences between current and deferred tax rates 

Differing tax rates on overseas earnings

Unrecognised losses

Foreign exchange

Share options

Movement in other tax provisions

Total taxation

18,157

3,449

1,888

(4)

298

4,972

114

246

96

(352)

131

10,838

13,016

2,473

614

(18)

(132)

1,811

40

–

–

(7)

208

4,989

The taxation charge for the year ended 31 December 2020 included the impact on deferred 
tax of the increase in the main rate of UK tax from 17% to 19%, following the abandonment of 
the proposed reduction to 17% in the Budget on 11 March 2020. 

A further change to UK corporation tax was announced in the Budget on 3 March 2021, 
increasing the main rate of UK corporation tax from 19% to 25% with effect from 1 April 
2023. The taxation charge for the year ended 31 December 2021 includes the impact on 
deferred tax of this increase.

The Group has calculated ‘underlying effective tax rate’ as an alternative performance 
measure in note 34.

9. Dividends
An interim dividend of 0.563p per share for the 2021 financial year was paid on 7 January 
2022. The Board is proposing a final dividend payment of 1.128p per share for 2021, taking 
the total dividend payment for the year to 1.691p (2020: 1.610p).

Amounts recognised as distributions to owners in 2021

Interim dividend for the 2020 financial year

Final dividend for the 2020 financial year

Total dividend

Year ended
 31 December 2021

Pence/share

£000s

0.536

1.074

1.610

2,857

5,747

8,604

The interim dividend for 2020 was paid on 7 January 2021. The final dividend for 2020 was 
paid on 8 July 2021.

Amounts recognised as distributions to owners in 2020

Interim dividend for the 2019 financial year

Year ended
 31 December 2020

Pence/share

0.536

£000s

2,837

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10. Earnings per share (EPS)

The resulting EPS measures are:

Basic EPS is calculated by dividing the earnings attributable to Ordinary shareholders by the 
weighted average number of Ordinary shares in issue during the year. For diluted EPS, the 
weighted average number of Ordinary shares in issue is adjusted to assume conversion of all 
dilutive potential Ordinary shares. There are no differences in earnings used to calculate each 
measure as a result of the dilutive employee share options. 

A reconciliation of the weighted average number of Ordinary shares used in the measures is 
given below: 

Basic EPS

Diluted EPS

Underlying basic EPS

Underlying diluted EPS

11. Goodwill and intangible assets

Year ended 
31 December 2021
Pence

Year ended 
31 December 2020
Pence

1.37

1.35

6.39 

6.30 

1.51

1.49

5.11

5.05

Basic EPS calculation

Employee share options

Diluted EPS calculation

Year ended 
31 December 2021

Year ended 
31 December 2020

535,295,583

531,062,798

7,039,113

6,256,040

542,334,696

537,318,838

The underlying basic EPS is intended to demonstrate recurring elements of the results of the 
Group before non-underlying items. A reconciliation of the earnings used in the different 
measures is given below:

Earnings for basic and diluted EPS

Non-underlying items (note 5)

Earnings for underlying basic and diluted EPS

Year ended 
31 December 2021
£000s

Year ended 
31 December 2020
£000s

7,319

26,866

34,185

8,027

19,129

27,156

 Goodwill
£000s

Consumer Healthcare 
brands and distribution 
rights £000s

Prescription Medicines 
brands and distribution 
rights £000s

Computer 
software 
£000s

Total
£000s

The Group

Cost

At 1 January 2021

32,404

258,203

152,890

–

443,497

Transfer from property, 
plant and equipment

Additions

Acquisition (note 31)

Exchange adjustments

–

–

(183)

161

At 31 December 2021

32,382

Amortisation and 
impairment

At 1 January 2021

1,144

Non-underlying 
impairment for the year

Non-underlying 
amortisation for the year

Underlying amortisation 
for the year

–

–

–

At 31 December 2021

1,144

Net book amount

At 31 December 2021

31,238

At 1 January 2021

31,260

–

–

–

1,877

260,080

6,459

1,500

226

–

8,185

–

–

–

(1,346)

11,037

11,037

4,006

4,006

–

–

(183)

692

151,544

15,043

459,049

23,022

4,650

6,942

–

–

–

30,625

6,150

7,168

–

34,614

1,362

1,362

1,362

45,305

251,895

251,744

116,930

13,681

413,744

129,868

–

412,872

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11. Goodwill and intangible assets continued

The Group

Cost

At 1 January 2020

Acquisition (note 31)

Disposals 

Exchange adjustments

At 31 December 2020

Amortisation and impairment

At 1 January 2020

Non-underlying impairment for  
the year

Non-underlying amortisation for  
the year

At 31 December 2020

Net book amount

At 31 December 2020

At 1 January 2020

 Goodwill
£000s

Consumer Healthcare 
brands and distribution 
rights £000s

Prescription Medicines 
brands and distribution 
rights £000s

Total
£000s

16,532

15,427

–

445

32,404

–

1,144

–

1,144

31,260

16,532

171,102

89,990

–

(2,889)

258,203

4,226

2,007

226

6,459

251,744

166,876

152,439

340,073

–

105,417

(714)

1,165

(714)

(1,279)

152,890

443,497

7,187

11,413

8,906

12,057

6,929

7,155

23,022

30,625

129,868

412,872

145,252

328,660

Computer software
The addition of the computer software intangible asset is explained in note 2.3 judgements 
and estimates. 

Prior year acquisitions
On 29 December 2020 the Group completed the acquisition of 100% of the share capital of 
Biogix Inc, a privately held, US-based consumer healthcare company. The acquisition brings 
into the Group a highly successful and fast-growing brand, Amberen, with significant near-
term growth potential. As part of this acquisition an intangible brand asset with fair value of 
$121.0m (£90.0m) for the product Amberen, and goodwill of $20.8m (£15.4m), have been 
recognised (note 31). During the year ended 31 December 2021, there was a reduction in the 
working capital adjustment paid in cash by $0.2m (£0.2m). 

Useful economic lives
As a result of the 2020 Strategic Review, the Group segregated its portfolio of assets into two 
areas: Consumer Healthcare brands and Prescription Medicines. Following this determination the 
Directors considered the continuing appropriateness of indefinite useful lives which have previously 
been adopted across the intangible brand asset portfolio. This is in the context of the focus on 
growing Consumer Healthcare brands, their increasing dominance of the portfolio and the roll-
out of Digital Excellence programmes, as further detailed in the Strategic Report. Prescription 
Medicines have been considered in the context of more limited requirement for promotional 
investment, and potential exposure to other market factors detailed further below. 

For the majority of Consumer Healthcare brand assets, indefinite useful lives have been 
judged to remain appropriate. This is due to the expected long-term growth profile of the 
Consumer Healthcare business and the enduring nature of the brands, which are supported 
by continuing marketing spend.

For Prescription Medicines brand assets, finite useful lives of up to 20 years were adopted 
prospectively from 1 January 2020. The determination of this lifespan has taken into account 
all relevant factors for each individual asset, including typical pharmaceutical asset life cycles 
and the potential development of alternative treatments over time. 

116

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11. Goodwill and intangible assets continued
Useful economic lives continued
Certain brands were acquired with patent protection, which lasts for a finite period of time. It is the 
opinion of the Directors that these patents do not provide any incremental value to the value of the 
brand and therefore no separate value has been placed on these patents. This assessment is based 
on a view of future profitability after patent expiry and past experience with similar brands.

It is the opinion of the Directors that the indefinite life assets meet the criteria set out in IAS 38. 
This assessment is made on an asset-by-asset basis taking into account:

 › how long the brand has been established in the market and subsequent resilience to 

economic and social changes;
stability of the industry in which the brand is used;

 ›
 › potential obsolescence or erosion of sales;
 › barriers to entry;
 › whether sufficient marketing and promotional resourcing is available; and
 › dependency on other assets with defined useful economic lives.

The Prescription Medicines brand assets have a weighted average remaining life of 18 years 
at 31 December 2021 (2020: 19 years).

The net book value of intangible assets and goodwill which are considered to have indefinite 
useful lives are allocated to CGUs in the following table. Goodwill relating to the acquisition 
of certain assets and businesses from Sinclair IS Pharma plc is allocated to the group of 
related Consumer Healthcare and Prescription Medicines product CGUs. Other goodwill 
amounts are allocated to the product CGU with which they were originally acquired. 
Intangible assets that are considered to have indefinite lives all relate to the Consumer 
Healthcare segment, except for Sinclair Prescription Medicines goodwill.

Amberen

Nizoral

Vamousse

MacuShield

Ashton and Parsons

Lefuzhi

Anbesol

Aiweidi

Opus range

Cambridge intangibles

Products acquired from Sinclair 

Kelo-cote (non EU, excluding US)

Kelo-cote (EU)

Aloclair

Atopiclair

Goodwill – Sinclair Prescription Medicines

Goodwill – Sinclair Consumer Healthcare

31 December 2021

Consumer healthcare 
brands and  
distribution rights 
£000s

89,629

60,307

11,596

8,740

1,562

1,514

987

212

–

–

40,842

17,800

14,000

2,300

–

–

Total
£000s

104,808

60,307

11,596

10,488

1,562

1,514

987

212

1,849

598

40,842

17,800

14,000

2,300

1,347

10,517

249,489

280,727

 Goodwill
£000s

15,179

–

–

1,748

–

–

–

–

1,849

598

–

–

–

–

1,347

10,517

31,238

The difference in Amberen values in the table compared to note 31 are the result of foreign 
exchange retranslation of these US Dollar denominated assets.

117

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Additional Information

11. Goodwill and intangible assets continued
Impairment
As explained in note 2.9, all intangible assets are stated at the lower of cost less 
accumulated amortisation and impairment or the recoverable amount. 

The carrying amounts of the Group’s non-financial assets are reviewed at each reporting 
date to determine whether there is any indication of impairment. For intangible assets with 
an indefinite life, assets with a finite life that show indicators of impairment, and goodwill this 
includes estimation of the recoverable amount. These assets are tested at CGU level (or at 
group of CGUs level in the case of goodwill relating to the acquisition of certain assets and 
businesses) as the Directors believe these CGUs generate largely independent cash inflows.

The impairment test involves determining the recoverable amount of the relevant cash-
generating unit, which corresponds to the higher of the fair value less costs to sell or its value 
in use.

The value in use calculation uses cash flow projections based on financial forecasts for up to 
the next five years extrapolated to perpetuity. Financial forecasts for the following year are 
based on the approved annual budget. Financial forecasts for years two to five are based on 
the approved long range plan. Margins are based on past experience and cost estimates.

As a result of the impairment review for the Year Ended 31 December 2021, the following 
impairment charges were identified:

 › Haemopressin, a prescription medicine brand and distribution rights asset, impaired by 

£3.9m due to market factors.

 › Other prescription medicine brand and distribution rights assets impaired by £0.8m due  

to increasing costs resulting from changes in the regulatory framework.

 › Consumer healthcare brand and distribution rights assets impaired by £1.5m due to 

viability of future sales in the current market. 

Key source of estimation uncertainty – value in use assumptions
For the year end impairment review, key assumptions on which cash flow projections depend 
are as follows (including our assessment of the estimation uncertainty arising):

Discount rates

 › Methodology: Cash flows are discounted at an appropriate rate, based on the Group’s 
post-tax Weighted Average Cost of Capital (WACC) adjusted where appropriate for 
country-specific risks, of between 6.3%–8.6%, or pre-tax 7.9%–10.8% (2020: 6.7%–
11.0%, or pre-tax 8.4%–13.8%). The Group’s WACC has remained consistent overall, but 
the range of discount rates for individual brands is lower due to changes in the country 
profile of the individual brands. The Group risk-free rate has increased due to changes in 
government bond yields, the small stock premium has reduced to recognise the Group’s 
growth in market capitalisation and the equity beta has remained consistent based on 
sector market data. The risk premium to recognise the impact of COVID-19 remains 
consistent with the prior year.

 › Estimation uncertainty: The assumptions included in the compilation of the CGU specific 
discount rates are designed to approximate the discount rate that a potential market 
participant would adopt. Given the nature of the Group’s business model, the discount  
rate necessarily includes estimation uncertainty.

Forecast cash flows
 › Methodology: Approved budgets and forecasts for up to five years, based on 

management’s best estimate of cash flows by individual CGU. These forecasts are then 
uplifted for the CGU’s remaining useful economic life, or to perpetuity for assets with 
indefinite useful lives, using growth rates between -2.5% to 2.0% (2020: -3.0% to 2.0%) 
based on the Group’s long-term projections. 

 › Estimation uncertainty: The growth rates assumed in the Group’s budgets and forecasts 
inherently include estimation uncertainty relating to the achievement of commercial 
initiatives and external factors such as competition. 

Sensitivity analysis 
The Group has conducted sensitivity analysis on the impairment tests. The valuations generally 
indicate sufficient headroom, and the Group does not consider that any reasonably possible 
change in key assumptions could result in an impairment for the majority of intangible assets. 

118

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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11. Goodwill and intangible assets continued
Management have identified a specific source of estimation uncertainty in relation to the 
Haemopressin asset. The value of the asset is currently supported by projected future cash 
flows in relation to a third-party licence agreement which is awaiting regulatory approval. It is 
considered likely that this approval will be granted, and the resulting cash flows are expected 
to support the carrying value of the asset. However, if approval is not granted, this would 
result in an additional impairment charge of £4.7m, the carrying value post impairment.

As there is uncertainty in relation to the projected cash flows in relation to this CGU if the 
licence is granted, additional risk has been factored into the value in use calculation. Based 
on data from existing markets, the resulting value in use calculations are considered to reflect 
the appropriate level of risk. The following table shows the key assumptions made.

Value in use  
calculation assumptions 

Pre-tax  
discount 
rate %

Risk-related reduction 
of projected cash flows

Brand 1

Brand 2

Remaining UEL years

rights assets with lower headroom (‘Brand 1’ and ‘Brand 2’), a reasonably possible change 
in two key assumptions could cause the carrying amount to exceed the recoverable amount. 
These assumptions are detailed as follows.

The cash flow projections included specific estimates for five years and a terminal growth rate 
thereafter. The terminal growth rates are determined based on management’s estimate of the 
long-term prospects for each product.

Value in use  
calculation assumptions 

Pre-tax  
discount 
rate %

9.2

8.0

Terminal 
margin 
growth 
rate %

0.0

2.0

Individual assumptions 
required for the estimated 
recoverable amount to equal 
to the carrying amount

Pre-tax  
discount  
rate %

10.8

9.2

Terminal 
margin  
growth  
rate %

(2.8)

(0.5)

Remaining 
UEL years

18

18

Haemopressin

7 years from date of approval

8.9%

25%

The following table shows the potential impact of reasonably possible changes to individual 
assumptions on the estimated recoverable amount of the CGUs. 

The following table shows the potential impact of reasonably possible changes to the key 
assumptions made.

Haemopressin

Decrease in CGU recoverable amount £000s

2.0% increase in  
pre-tax discount 
rate

Further reduction in 
projected cash flows 
(50% reduction)

(602)

(1,784)

Brand 1

Brand 2

Management have identified that for certain prescription medicines brands and distribution 

Decrease in CGU recoverable amount £000s

Headroom

2.0% increase in  
pre-tax discount rate

2.0% reduction in 
terminal margin growth 
rate

355

122

(579)

(168)

(350)

(140)

119

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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12. Property, plant and equipment

The Group

Cost

At 1 January 2021

Additions

Transfer to intangible assets

Disposals

Computer  
software and 
equipment
£000s

Fixtures,
 fittings & 
equipment
£000s

Plant & 
machinery
£000s

Right of 
 use lease 
assets
£000s

Total
£000s 

13,048

162

(11,037)

2,511

1,323

–

(136)

(104)

32

41

–

–

6,739

22,330

275

1,801

–

(11,037)

(708)

(948)

At 31 December 2021

2,037

3,730

73

6,306

12,146

Depreciation

At 1 January 2021

Provided in the year

Effect of movements in exchange rates

Disposals

At 31 December 2021

Net book amount

At 31 December 2021

At 1 January 2021

1,620

1,408

186

–

446

(9)

(136)

(104)

1,670

1,741

367

11,428

1,989

1,103

8

28

–

–

36

37

24

3,373

915

–

6,409

1,575

(9)

(415)

(655)

3,873

7,320

2,433

4,826

3,366

15,921

The Group

Cost

At 1 January 2020

Additions

Acquisition (note 31)

Effect of movements in exchange rates

Disposals

At 31 December 2020

Depreciation

At 1 January 2020

Provided in the year

Effect of movements in exchange rates

Disposals

At 31 December 2020

Net book amount

At 31 December 2020

At 1 January 2020

Computer  
software and 
equipment
£000s

Fixtures,
 fittings & 
equipment
£000s

Plant & 
machinery
£000s

Right of 
 use lease 
assets
£000s

8,511

4,562 

–

29

(54)

13,048

1,172

504

(2)

(54)

2,699

50

–

(3)

(235)

2,511

1,200

444

(1)

(235)

1,620

1,408

11,428

7,339

1,103

1,499

14

–

18

–

–

32

4

4

–

–

8

24

10

Total
£000s 

16,517

5,737

312

53

(289)

5,293

1,125

294

27

–

6,739

22,330

2,587

801

(15)

–

4,963

1,753

(18)

(289)

3,373

6,409

3,366

2,706

15,921

11,554

Property, plant and equipment of £4.1m is located within the United Kingdom (2020: 
£14.4m). The balance is located in France, China, Singapore, Spain, Germany and the 
United States of America. Right of use assets relate to the Group’s leased offices. 

120

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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13. Investments

The Company

Cost

At 1 January 2021

Net movements 

At 31 December 2021

At 1 January 2020

Net movements

At 31 December 2020

Investment and 
loans to subsidiary 
undertakings 
£000s

199,776

(428)

199,348

194,630

5,146

199,776

The investment balance includes outstanding intercompany debt due from subsidiaries of 
£176.1m (note 29). The Directors do not consider that this amount will be demanded by 
the Company and therefore it has been classified as an investment. No provision has been 
recognised for estimated credit losses on loans to subsidiaries, as it is considered these would 
be immaterial.

The net movement for the year ended 31 December 2021 included interest charged of £6.1m 
(2020: £5.8m), the recharge of the share option charge £1.1m (2020: £1.1m), the dividend 
received of £2.6m (2020: £2.8m) and payments received to reduce the loan.

The subsidiary and associated undertakings where the Group held 20% or more of the equity 
share capital at 31 December 2021 are shown below:

Company

Advanced Bio-Technologies Inc.

Alliance Pharma France SAS

Country of registration  
or incorporation

%

owned Nature of business

USA

France

100 Pharmaceutical sales

100 Pharmaceutical sales

Alliance Pharma (Singapore) Private Limited*

Singapore

100 Pharmaceutical sales

Alliance Pharma S.r.l.

Italy

100 Pharmaceutical sales

Alliance Pharmaceuticals Limited*

England & Wales

100 Pharmaceutical sales

Alliance Pharmaceuticals (Asia) Limited*

Hong Kong

100 Pharmaceutical sales

Company

Country of registration  
or incorporation

%

owned Nature of business

Alliance Lifescience Technology (Shanghai) Co.,Limited China

Alliance Pharmaceuticals Spain SL*

Alliance Pharma Inc.

Spain

USA

100 Pharmaceutical sales

100 Pharmaceutical sales

100 Pharmaceutical sales

Alliance Pharmaceuticals (Thailand) Co., Ltd

Thailand

100 Pharmaceutical sales

Alliance Pharmaceuticals (Philippines) Corporation

Philippines

100 Pharmaceutical sales

Alliance CHC (India) Private Limited 

Biogix Inc.

India

USA

100 Pharmaceutical sales

100 Pharmaceutical sales

Maelor Laboratories Limited 

England & Wales

100 Non-trading

Alliance Pharmaceuticals GmbH*

Germany

Alliance Pharmaceuticals GmbH* – Swiss Branch

Switzerland

Alliance Pharmaceuticals SAS*

France

100 Non-trading

100 Non-trading

100 Non-trading

Opus Healthcare Limited

Republic of Ireland

100 Non-trading

Alliance Pharma (Ireland) Limited

Republic of Ireland

100 Non-trading

Alliance Consumer Health Limited

England & Wales

100 Dormant

Alliance Generics Limited

Alliance Health Limited

Alliance Healthcare Limited

Caraderm Limited

Dermapharm Limited

MacuVision Europe Limited

Opus Group Holdings Limited

Opus Healthcare Limited

* 

Investments held directly by Alliance Pharma plc.

England & Wales

100 Dormant

England & Wales

100 Dormant

England & Wales

100 Dormant

Northern Ireland

100 Dormant

England & Wales

100 Dormant 

England & Wales

100 Dormant

England & Wales

100 Dormant

England & Wales

100 Dormant

121

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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13. Investments continued
The registered address in each country is as follows:

Territory

Thailand

Territory

USA

Company

Registered Office Address

Advanced Bio-Technologies Inc. One Urban Center, 4830 West Kennedy Blvd, Suite 

England & Wales

All Companies

Alliance Pharma Inc.

Biogix Inc.

600, Tampa FL 33609, United States

11000 Regency Pkwy, Ste 106, Cary NC 27518, 
United States

201 Continental Blvd., Suite 230, El Segundo, 
California 90245, United States

France

Alliance Pharmaceuticals SAS

35 rue d’Artois Paris 75008, France

China

Germany

Hong Kong

Alliance Pharma France SAS

35 rue d’Artois Paris 75008, France

Alliance Pharmaceuticals 
Lifescience Technology (Shanghai) 
Co.,Limited

Suite 1004, NanFung Tower, No. 1568, Road 
Huashan, Shanghai, 200030, P.R.China 

Alliance Pharmaceuticals GmbH Hanseatic Trade Center, Am Sandtorkai 41, D-20457 
Hamburg, Germany

Alliance Pharmaceuticals  
(Asia) Limited

Room 2105, 21/F Office Tower, Langham Place, 8 
Argyle Street, Mongkok, Kowloon, Hong Kong

Italy

Alliance Pharma S.r.l.

Viale Francesco Restelli 5, 20124, Milano, Italy

Republic of Ireland

Alliance Pharma (Ireland) Limited 6th Floor, South Bank House, Barrow Street, Dublin 4

Opus Healthcare Limited

6th Floor, South Bank House, Barrow Street, Dublin 4

Singapore

Alliance Pharma (Singapore) 
Private Limited

1 Scotts Road, Shaw Centre 22-06, 228208, 
Singapore

Spain

Alliance Pharmaceuticals Spain SL Regus Business Center Torre de Cristal, Paseo de la 

Switzerland (Branch) Alliance Pharmaceuticals  

GmbH Düsseldorf

Casstellana, 259 C Planta 18, Cuatro Torres Business 
area 28046, Madrid, Spain

Bahnhofstrasse 37, Postfach 2818, CH-8021 Zürich, 
Switzerland

Company

Registered Office Address

Alliance Pharmaceuticals 
(Thailand) Co., Ltd

No. 444 Olympia Thai Tower, 8th Floor, Ratchadapisek 
Road, Samsennok Sub-district, Huaykwang District, 
Bangkok, Thailand

Avonbridge House, Bath Road, Chippenham, Wiltshire,  
SN15 2BB

Northern Ireland

Caraderm Limited

6 Trevor Hill, Newry, County Down, BT34 1DN

Philippines 

Alliance Pharmaceuticals 
(Philippines) Corporation 

India 

Alliance CHC (India)  
Private Limited 

30/F 88 Corporate Center Sedeno Cor.Valero STS., 
BEL-AIR 1209, City of Makati NCR, Fourth District, 
Philippines 

314, Bhaveshwar Arcade Annexe, LBS Marg, Opp. 
Shreyas Cimema, Ghatkopar West Mumbai, Bandra 
Suburban, MH 400086 IN 

Unless otherwise stated, the share capital comprises Ordinary shares and the ownership 
percentage is provided for each undertaking. All subsidiary undertakings prepare accounts  
to 31 December.

Maelor Laboratories Limited is exempt from the Companies Act 2006 requirement relating to 
the audit of its individual accounts by virtue of Section 479A of the Act as the company has 
guaranteed the subsidiary company under Section 479C of the Act.

14. Inventories

The Group

Finished goods and materials

Inventory provision

31 December 2021
£000s

31 December 2020
£000s

24,311

(3,236)

21,075

25,916

(2,999)

22,917

Inventory costs expensed through the Income Statement during the year were £52,932,000 
(2020: £39,636,000). During the year £534,000 (2020: £1,284,000) was recognised as 
an expense relating to the write-down of inventories to net realisable value. 

122

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Additional Information

15. Trade and other receivables

Trade receivables

Other receivables

Prepayments

Accrued income

The Group

The Company

31 December 2021
£000s

31 December 2020
£000s

31 December 2021
£000s

31 December 2020
£000s

23,929

1,953

3,102

1,837

30,821

19,834

1,544

898

2,838

25,114

–

31

8

–

39

–

25

11

–

36

Accrued income, which is all classified as not past due, represents amounts owed 
unconditionally to the Group which have not been invoiced at the year end. For these  
assets, only the passage of time is required before payment becomes due.

The ageing of trade receivables of the Group as at 31 December is detailed below:

Trade receivables, net of estimated  
allowances for expected credit losses

31 December 2021
£000s

31 December 2020
£000s

Trade receivables, gross of estimated allowances for expected 
credit losses

31 December 2021
£000s

31 December 2020
£000s

Not past due

1–30 days past due

31–60 days past due 

61–90 days past due 

Past 91 days

20,405

2,573

633

389

780

24,780

15,764

2,550

1,606

31

524

20,475

As at 31 December 2021, trade and other receivables of £851,000 (2020: £641,000) were 
past due and impaired.

To manage credit risk customers are required to pay in accordance with agreed terms. Our 
settlement terms are generally due within 30 or 60 days from the end of the month of sale.

16. Cash and cash equivalents

Not past due

1–30 days past due

31–60 days past due 

61–90 days past due 

Past 91 days

20,405

2,573

633

318

–

15,764

2,550

1,520

–

–

Sterling

Euros

US Dollars

Thai Baht

23,929

19,834

Other currencies

Cash at bank and in hand

The Group

The Company

31 December 2021
£000s

31 December 2020
£000s

31 December 2021
£000s

31 December 2020
£000s

17,541

3,862

2,427

3,060

2,171

29,061

15,842

2,039

7,495

2,637

885

28,898

141

297

–

–

–

–

–

–

–

–

141

297

123

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Additional Information

17. Trade and other payables 

The Group

The Company

31 December 2021
£000s

31 December 2020
£000s

31 December 2021
£000s

31 December 2020
£000s

Trade payables

8,341

11,275

Other taxes and social 
security costs

Accruals 

Other payables

Lease liabilities

2,773

17,512

848

456

2,440

13,639

418

964

29,930

28,736

–

–

368

–

–

368

16

–

290

–

–

306

18. Loans and borrowings
The Group has a £165m fully Revolving Credit Facility (‘RCF’), together with a £50m 
accordion facility, with a syndicate of lenders. This facility is available until July 2024. 
This has been classified as a non-current liability (note 2.18). The bank facility is secured 
by a fixed and floating charge over the Company’s and Group’s assets registered with 
Companies House.

Movement in loans and borrowings

At 1 January 

Net (payments)/receipts from borrowing

Additional prepaid arrangement fees

Amortisation of prepaid arrangement fees

Exchange movements*

At 31 December

31 December 2021
£000s

31 December 2020
£000s

138,328

(22,587)

–

628

(309)

77,040

61,054

(362)

578

18

116,060

138,328

*  

 Exchange movements on loans and borrowings with effective net investment hedges are reported in other comprehensive income and accumulated in 
the translation reserve.

19. Other non-current liabilities

The Group

 The Company

31 December 2021
£000s

31 December 2020
£000s

31 December 2021
£000s

31 December 2020
£000s

Lease liabilities

Other non-current liabilities

2,426

211

2,637

2,731

469

3,200

–

–

–

Non-current

Bank loans:

Secured 

Finance issue costs

The Group

 The Company

31 December 2021
£000s

31 December 2020
£000s

31 December 2021
£000s

31 December 2020
£000s

20. Provisions

117,025

(965)

116,060

139,920

(1,592)

138,328

–

–

–

–

–

–

At 1 January 2021

Charge to Income Statement

Provisions utilised during the year

Exchange differences

At 31 December 2021

CMA provision 
(£000s)

Restructuring 
provision 
(£000s)

–

7,900

–

–

7,900

 – 

1,869 

(259)

(41)

1,569 

–

–

–

Total 
(£000s)

–

9,769

(259)

(41)

9,469

124

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

20. Provisions continued
On 23 May 2019 the UK’s Competition and Markets Authority (‘CMA’) issued a Statement 
of Objection alleging anti-competitive agreement involving the Group and certain other 
pharmaceutical companies in relation to the sale of prescription prochlorperazine. 
Prochlorperazine is one of the Group’s smaller products and had peak sales in 2015 of £1.9m 
and sales of £0.7m in 2021.

On 3 February 2022, the CMA announced its finding that four companies, including Alliance, 
had infringed competition law (the ‘Infringement Decision’). The Directors fundamentally 
disagree with the CMA’s finding. 

The Group believes that it has a strong case and will be appealing the CMA’s decision, and 
the proposed fine of £7.9m, at the Competition Appeal Tribunal which is expected to be 
heard in late 2022/early 2023, although the timing may be extended due to the current 
workload pressures within the court system. Historically, the Group’s assessment was that 
there were no matters for which a provision was required, however the Infringement Decision 
has caused the Group to revisit this assessment. 

Despite the Group’s intention to appeal, the Directors believe that, as a result of the 
Infringement Decision, a provision of £7.9m should be recorded at 31 December 2021 
(2020: £Nil) 

This reflects the amount of the proposed fine communicated by the CMA, and therefore, 
notwithstanding the Directors belief as to the merits of the grounds on which it will be 
appealing the CMA decision, the Directors consider this to be the appropriate position given 
that, in the event that the Group’s appeal proves to be unsuccessful, the ultimate level of the 
fine cannot be greater than this. In addition, in the event the Group’s appeal were to prove to 
be unsuccessful, the Directors consider that there are strong grounds upon which the amount 
of the fine could be reduced. However, as this is a matter which cannot be predicted with 
certainty at this time the Directors believe that the most appropriate course of action is to 
include the maximum potential amount of the fine.

If the appeal is unsuccessful, the Group may also be liable for a proportion of the legal costs 
of the CMA relating to the appeal. The Group has not recorded a provision in relation to 
these potential litigation costs as these costs relate to the decision to appeal which was taken 
after the year end and their amount cannot be reliably estimated.

In accordance with IAS 37.92, the Group does not provide further information on the grounds 
that this could seriously prejudice the outcome of the appeal.

The restructuring provision of £1.6m at 31 December 2021 (2020: £Nil) relates to the 
balance of restructuring costs in relation to the closure of the Milan office following a change 
to the operating model for our direct-to-market business in Italy. The related outflows are 
expected to occur in the year ended 31 December 2022.

21 Financial instruments
The Group uses financial instruments comprising borrowings, derivatives, cash and liquid 
resources, and various items such as trade receivables and trade payables that arise directly 
from its operations. The main risks arising from the Group’s financial instruments are liquidity 
risk, interest rate risk, foreign currency risk and credit risk. The Board is responsible for risk 
management policies on managing each of these, which are summarised below, except credit 
risk which is detailed in note 15.

Liquidity risk
The Group’s operations are financed by retained earnings and bank borrowings, with 
additional equity being raised on a periodic basis to finance larger acquisitions. Borrowings 
are denominated in Sterling, Euro and US Dollars. The purpose of Euro and US Dollar 
borrowings are to manage the currency exposure arising from the Group’s operations.

The Group has a £165m fully Revolving Credit Facility (‘RCF’), together with a £50m 
accordion facility, with a syndicate of lenders. This facility is available until July 2024. 
The RCF is drawn in short to medium-term tranches of debt which are repayable within 12 
months of draw-down. These tranches of debt can be rolled over provided certain conditions 
are met, including covenant compliance. The Group considers that it is highly unlikely it would 
be unable to exercise its right to roll-over the debt. This is due to mitigating actions it could 
take to maintain compliance with these conditions, including future covenant requirements, 
even in downside scenarios. The Directors therefore believe that the Group has the ability and 
the intent to roll-over the drawn RCF amounts when due and consequently has presented the 
RCF as a non-current liability.

125

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

21 Financial instruments continued
Liquidity risk continued
The Group also has access to an overdraft facility of £2.0m.

The maturity profile of the Company’s financial gross liabilities (capital and interest) at the 
year end is as follows:

The maturity profile of the Group’s financial gross (capital and interest) liabilities, except 
forward foreign exchange contracts for which maturity is disclosed separately, at the year-
end is as follows:

Trade and other payables 

31 December 2021 
In one year or less 
£000s

31 December 2020 
In one year or less 
£000s

368

306

31 December 2021

In one year 
or less
£000s

In more than 
one year, but not 
more than two
£000s

In more than two 
years, but not 
more than five
£000s

In more than 
five years
£000s

36,166

117,057

539

153,762

–

–

391

391

–

–

900

900

–

–

1,244

1,244

Total
£000s

36,166

117,057

3,074

156,297

Trade and other 
payables

Bank loans*

Lease liabilities

* 

 Includes an amount of £117.1m (2020: £140.0m) in respect of gross contractual cash flows payable under the RCF; these are shown as due within one 
year or less to reflect the contractual maturity of the tranches drawn down at 31 December 2021. The RCF is classified as a non-current liability as the 
Directors have assessed that the Group has the ability and the intent to roll-over the drawn RCF amounts when due.

31 December 2020

In one year 
or less
£000s

In more than 
one year, but not 
more than two
£000s

In more than two 
years, but not 
more than five
£000s

In more than 
five years
£000s

27,220

139,995

964

168,179

–

–

544

544

–

–

1,086

1,086

–

–

1,521

1,521

Trade and other 
payables

Bank loans*

Lease liabilities

Interest rate risk
The Group’s debt is provided on a floating interest rate basis.

The interest rate exposure of the financial liabilities of the Group at the period end was:

Floating rate interest exposure

At 31 December 2021

Bank loans – Sterling denominated

Bank loans – Euro denominated

Bank loans – US Dollar denominated

Total financial liabilities

Unamortised issue costs

Net book value of  
financial liabilities

31 December 2021 
£000s

31 December 2020
£000s

96,817

7,895

12,313

117,025

(965)

105,317

9,281

25,322

139,920

(1,592)

116,060

138,328

Total
£000s

27,220

139,995

4,115

171,330

The Sterling floating rate borrowings bear interest at a rate based on LIBOR for the year 
ended 31 December 2021. From 1 January 2022 the Sterling floating rate borrowings will 
bear interest at a rate based on SONIA. This is not expected to have a significant impact on 
the Group’s financial instruments and associated risks. The Euro floating rate borrowings bear 
interest at a rate based on EURIBOR. The US Dollar floating rate borrowings bear interest at a 
benchmark rate (US Dollar LIBOR).

A 0.5% increase in LIBOR would have reduced pre-tax profits by approximately £0.5m in 
2021. A 0.5% decrease would have the opposite effect.

126

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

21 Financial instruments continued
Interest rate risk continued
A 0.5% increase in EURIBOR would have reduced pre-tax profits by approximately £0.1m 
in 2021. A 0.5% decrease would have no effect on profit as the Group’s Euro denominated 
borrowings have an interest rate floor.

A 0.5% increase in US LIBOR would have reduced pre-tax profits by approximately £0.1m in 
2020. A 0.5% decrease would have the opposite effect.

Currency risk
The Group is exposed to transactional foreign currency risk to the extent that there is a 
mismatch between the currencies in which sales, purchases, receivables and borrowings 
are denominated and the respective functional currencies of Group companies. The 
functional currencies of Group companies are primarily Sterling, Euro, US Dollars and Hong 
Kong Dollars. 

Approximately 23% of the Group’s sales are invoiced in Euro, 32% invoiced in US Dollar and 
9% invoiced in Hong Kong Dollar. The majority of other Group sales are invoiced in Sterling. 

The Group’s risk management policy is to hedge up to 75% of its estimated net foreign 
currency exposure in respect of forecast sales and purchases for up to the next 18 months at 
any point in time. The Group uses forward foreign exchange contracts to hedge its currency 
risk. These contracts are generally designated as cash flow hedges.

After the impacts of hedging, 5% weakening or strengthening of Sterling against the Euro 
would have resulted in £0.3m gain or loss to EBITDA (note 34) in 2021. On the same basis, 
5% weakening or strengthening of Sterling against the US Dollar would have resulted in a 
£0.3m gain or loss to EBITDA in 2021. On the same basis, 5% weakening or strengthening of 
Sterling against the Hong Kong Dollar would have had no impact on EBITDA in 2021. 

Net investment hedges
The Group uses currency denominated borrowings to hedge the exposure of a portion of 
its net investment in overseas operations against changes in value due to changes in foreign 
exchange rates. The net investment hedge was tested for effectiveness during the year and 
found to be effective. As the Group repays its foreign denominated borrowings the hedged 
portion of the net investment is reduced.

Fair value measurement
The Group has adopted IFRS 13 for financial instruments that are measured in the Group 
balance sheet at fair value. This requires disclosure of fair value measurements by level of the 
following fair value measurement hierarchy:

 › quoted prices (unadjusted) in active markets for identical assets or liabilities (Level 1);

 ›

 ›

inputs other than quoted prices included within Level 1 that are observable for the asset  
or liability, either directly (that is, as prices) or indirectly (that is, derived from prices)  
(Level 2); and

inputs for the asset or liability that are not based on observable market data (that is, 
unobservable inputs) (Level 3). 

The Group’s financial instruments held at fair value (or for which fair value is disclosed) in the 
scope of IFRS 13 are as follows:

Forward foreign exchange contracts

Level

2

31 December 2021
Carrying value
£000s

31 December 2020
Carrying value
£000s

64

64

295

295

For the other financial assets and liabilities, the carrying amount is a reasonable 
approximation of fair value and therefore no further disclosure is provided. The valuation 
techniques used for instruments categorised in Level 2 are described below:

Forward foreign exchange contracts (Level 2)
The Group’s currency rate swaps are not traded in active markets. These have been fair 
valued using observable currency rates. The effects of non-observable inputs are not 
significant for currency rate swaps. 

Counterparty banks perform valuations of currency rate swaps for financial reporting 
purposes, determined by discounting the future cash flows at rates determined by year end 
spot and forward rate. The valuation processes and fair value changes are discussed by 
the Audit and Risk Committee and the Finance team at least every half year, in line with the 
Group’s reporting dates.

127

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Financial Statements

Additional Information

21 Financial instruments continued
Forward foreign exchange contracts (Level 2) continued
Forward foreign exchange contract assets and liabilities are presented in ‘Derivative financial 
instruments’ (either as asset or as liabilities) within the statement of financial position. 

At 31 December 2021, the Group held the following forward exchange contracts to hedge 
exposures to changes in foreign currency rates:

Maturity

1–6 months

6–12 months

More than  
one year

Forward exchange contracts

Net exposure (£000s)

Average GBP:USD forward contract rate

Average GBP:EUR forward contract rate

54

1.370

1.138

10

1.367

–

Average GBP:HKD forward contract rate

10.508

10.488

–

–

–

–

At 31 December 2020, the Group held the following forward exchange contracts to hedge 
exposures to changes in foreign currency rates:

Forward exchange contracts

Net exposure (£000s)

Average GBP:USD forward contract rate

Average GBP:EUR forward contract rate

Average GBP:HKD forward contract rate

Maturity

1–6 months

6–12 months

More than  
one year

157

1.283

1.124

–

153

1.306

1.112

–

(15)

1.342

1.115

–

Group
Classification of the Group’s financial assets and liabilities is set out below:

Financial assets

Financial assets at amortised cost

Trade receivables

Accrued income

Cash and cash equivalents

Derivative financial instruments

Used for hedging 

Financial liabilities

Financial liabilities at amortised cost

Trade and other payables

Loans and borrowings

Other liabilities

Lease liabilities

Derivative financial instruments

Used for hedging 

31 December 2021
£000s

31 December 2020
£000s

23,929

1,837

29,061

64

54,891

20,221

2,838

28,898

310

52,267

31 December 2021
£000s

31 December 2020
£000s

36,166

117,057

–

2,882

–

156,105

27,220

138,328

470

3,695

15

169,728

128

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

21 Financial instruments continued
Forward foreign exchange contracts (Level 2) continued 
Company
Classification of the Company’s financial instruments is set out below:

Financial assets

Financial assets at amortised cost

Trade and other receivables 

Financial liabilities

Financial liabilities at amortised cost

Trade and other payables 

Reconciliation to cash flow movements

The cash flow hedges were tested for 
effectiveness both retrospectively and 
prospectively as at 31 December 2021. 
They were found to be highly effective, with 
the ineffective element being immaterial. 
The amount recognised through the Income 
Statement in finance costs for interest 
rate swaps during the year was a charge 
of £Nil (2020: £49,000). The amounts 
recognised through the Income Statement 
in respect of the forward foreign exchange 
contracts during the year was a credit  
of £982,000 in revenue (2020: credit  
of £24,000). 

31 December 2021
£000s

31 December 2020
£000s

31

36

31 December 2021
£000s

31 December 2020
£000s

368

306

Gross loans and borrowings

Prepaid arrangement fees 

Accrued interest

Lease liabilities

Cash flows

Non-cash changes

2020
£000s

Principal
£000s

Interest
£000s

139,920

(22,587)

(1,592)

76

3,695

–

–

(924)

–

–

(2,861)

(103)

Foreign 
exchange*
£000s

(308)

–

–

–

Net additions
£000s 

Amortisation
£000s

Interest
£000s

–

–

–

111

–

627

–

–

–

–

2,817

103

2021
£000s

117,025

(965)

32

2,882

* 

Exchange movements on loans and borrowings are reported in other comprehensive income and accumulated in the translation reserve.

Derivative financial instruments

Current portion

Non-current portion

Forward exchange swap – cash flow hedge

 31 December 2021
Assets/(Liabilities)
£000s

 31 December 2020
Assets/(Liabilities)
£000s

64

–

64

310

(15)

295

129

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

22. Deferred tax

Reconciliation of deferred tax movements:

The Group

Accelerated capital allowances on tangible assets

Temporary differences: trading

Temporary differences: non-trading

Accelerated allowances on intangible assets

Initial recognition of intangible assets from business combination

Share-based payments

Foreign exchange forward contracts 

Losses

Recognised as:

Deferred tax asset

Deferred tax liability

 31 December 2021
£000s

 31 December 2020
£000s

(464)

291

915

(13,452)

(47,796)

1,819

(16)

501

(917)

492

623

(9,839)

(45,369)

1,024

(56)

–

(58,202)

(54,042)

3,526

(61,728)

2,139

(56,181)

1 January 
2021
£000s

Transfers 
£000s

Recognised 
in other 
comprehensive 
income/
directly in 
equity

Recognised
in the income 
statement
£000s

31 December 
2021
£000s

(55,208)

(917)

(670)

670

(284)

(5,086)

(61,248)

–

(217)

(464)

The Group

Non-current assets

Intangible assets

Property, plant and equipment

Non-current liabilities

Derivative financial instruments

Other non-current liabilities

(56)

623

Equity

Share option reserve

1,024

Temporary differences

Trading

Losses

Recognised as:

Deferred tax asset

Deferred tax liability

492

–

(54,042)

2,139

(56,181)

(54,042)

–

–

–

–

–

–

40

292

626

–

–

–

–

(16)

915

169

1,819

(201)

501

291

501

674

(4,834)

(58,202)

The Group has unrecognised deferred tax assets of £246,000 in relation to losses  
(2020: £nil).

3,526

(61,728)

(58,202)

130

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

22. Deferred tax continued

23. Share capital

Recognised 
 in other 
comprehensive 
income
£000s

1 January 
2020
£000s

Recognised
 directly 
in equity 
£000s

Recognised 
on acquisition 
£000s

Recognised
in the income 
statement
£000s

31 December 
2020
£000s

The Group

Non-current assets

–

(25,491)

(475)

(55,208)

At 1 January 2020 – Ordinary shares of 1p each

Issued during the year

At 31 December 2020 – Ordinary shares of 1p each

Issued during the year

 Allotted, called up and fully paid

No. of shares

529,402,619

3,516,492

 532,919,111

5,306,413

£000s 

5,294

35

5,329

53

5,382

–

–

36

(39)

–

–

(3)

Intangible assets

(29,242)

Property, plant and 
equipment

Non-current liabilities

Derivative financial 
instruments

Other non-current 
liabilities

Equity

(468)

(92)

662

Share option reserve

806

Temporary differences

Trading

234

(28,100)

Recognised as:

Deferred tax asset

1,710

Deferred tax liability

(29,810)

(28,100)

(42)

–

–

96

221

275

–

–

–

–

–

(407)

(917)

At 31 December 2021 – Ordinary shares of 1p each

538,225,524

Between 1 January 2021 and 31 December 2021 5,306,413 shares were issued on the 
exercise of employee share options (2020: 3,516,492). 

The holders of Ordinary shares are entitled to receive dividends as declared from time to time 
and are entitled to one vote per share at meetings of the Company.

–

–

(56)

623

122

1,024

37

492

(25,491)

(723)

(54,042)

2,139

(56,181)

(54,042)

131

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

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Financial Statements

Additional Information

23. Share capital continued
Potential share options commitment
Under the Group’s share option scheme for employees and Executive Directors, options have been granted to subscribe for shares in the 
Company at prices ranging from 0.00p to 102.80p (2020: 0.00p to 81.60p). Options are exercisable three years after date of grant, but in 
certain instances this can be extended to five years. Options outstanding are as follows:

Year of grant

2011

2012

2013

2013

2014

2015

2016

2016

2017

2018

2019

2019

2020

2020

2021

2021

Exercise price
Pence

31.00 and 34.12

29.25

37.25

35.75

33.75

43.75 and 46.75

47.50

47.50

53.00

81.60

76.90

0.00

73.70

0.00

102.80

0.00

Exercise from

Scheme

31 December 2021
Number (000s)

31 December 2020 
Number (000s)

2014

2015

2016

2018

2017

2018

2019

2021

2020

2021

2022

2022

2023

2023

2024

2024

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

CSOP

LTIP

CSOP

LTIP

CSOP

LTIP

–

41

263

–

321

1,219

1,077

1,800

2,877

4,171

5,422

529

5,042

628

7,012

531

186

75

892

450

494

1,852

3,896

3,500

4,694

6,322

6,793

596

6,129

704

–

–

30,933

36,583

The provision of shares to satisfy certain of the Group’s share option schemes can be facilitated by purchases of own shares by the Group’s 
Employee Benefit Trust. The cost of operating the Trust is borne by the Group but is not material. To date, no shares have been purchased by  
the Trust for satisfaction of outstanding or future share option awards.

Managing capital
Our objective in managing the business’s 
capital structure is to ensure that the Group 
has the financial capacity, liquidity and 
flexibility to support the existing business 
and to fund acquisition opportunities as 
they arise.

The capital structure of the Group consists 
of net bank debt and shareholders’ equity. 
At 31 December 2021 net debt was 
£87.0m (2020: £109.4m) (note 34),  
whilst shareholders’ equity was £282.5m 
(2020: £281.0m).

The business is profitable and cash-
generative. The main financial covenant 
applying to bank debt is that leverage (the 
ratio of net bank debt to EBITDA) should 
not exceed 3.0 times. The Group complied 
with this covenant in 2021 and 2020.

Smaller acquisitions are typically financed 
using bank debt, while larger acquisitions 
typically involve a combination of bank 
debt and additional equity. The mixture 
of debt and equity is varied, taking 
into account the desire to maximise the 
shareholder returns while keeping leverage 
at comfortable levels.

132

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

24. Share-based payments

Under the Group’s share option scheme for employees and Executive Directors, options to 
subscribe for shares in the Company are granted normally once each year. The contractual 
life of an option is ten years from date of grant. Generally, options granted become 
exercisable on the third anniversary of the date of grant, but in certain instances this can be 
extended to five years. Exercise of an option is normally subject to continued employment. 
Options are valued by a third-party provider using the Black-Scholes option-pricing model. 

Share options and weighted average exercise price are as follows for the reporting  
periods presented:

2021

2020

Number 
 (000s)

36,583

7,674

(5,306)

(8,018)

30,933

11,845

Weighted  
average price
Pence

47.02

93.94

50.07

63.27

71.62

60.12

Number 
 (000s)

34,484

6,833

(3,516)

(1,218)

36,583

12,539

Weighted  
average price
Pence

59.40

66.10

47.65

74.70

61.39

47.02

Outstanding at start of year

Granted

Exercised

Forfeited

Outstanding at end of year

Exercisable at end of year

Share options were exercised throughout the financial year. Share options were exercised at 
prices of between 29.25 and 81.60 pence per share. 

Certain options are subject to EPS or Total Shareholder Return (TSR) accretion performance 
criteria; those outstanding are as follows:

Year of grant

Exercise price
Pence

Exercise from

31 December 2021 
Number (000s)

31 December 2020 
Number (000s)

2013

2014

2015

2016

2016

2017

2018

2019

2019

2020

2020

2021

2021

35.75

33.75

43.75 

47.50

47.50

53.00

81.60

76.90

0.00

73.70

0.00

102.80

0.00

2018

2017

2018

2019

2021

2020

2021

2022

2022

2023

2023

2024

2024

–

92

104

155

1,800

323

1,639

911

529

837

628

1,172

531

8,721

450

204

317

545

3,500

1,028

2,411

1,127

596

917

704

–

–

11,799

The total expense for the year relating to share-based payment plans was £2.3m (2020: 
£1.4m), of which £2.0m (2020: £1.1m) related to equity-settled transactions and £0.3m 
(2020: £0.3m) related to cash-settled transactions.

It is assumed that, on average, options will be exercised after five years. The expected 
volatility is based on historical volatility (calculated based on the weighted average remaining 
life of the share options), adjusted for any expected changes to future volatility due to publicly 
available information. The risk-free rate of return is based on UK Government bonds of a term 
consistent with the assumed option life.

The cash-settled transaction expense includes provision for social security charges based on 
the applicable social tax rate applied to the number of share awards which are expected to 
vest, valued with reference to the year-end share price.

The estimated total equity-settled fair value of the share options granted on 29 September 
2021 was £1,551,000. The model inputs were a market price of 102.8p, expected volatility 
of 29.96% and a risk-free rate of 1.07%. 

133

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

25. Cash generated from operations 

Group

Company

 Year ended
31 December 2021
£000s

 Year ended
31 December 2020
£000s

Year ended
31 December 2021
£000s

Year ended
31 December 2020
£000s

7,319

10,838

3,646

(23)

(205)

–

8,027

4,989

2,657

(10)

644

308

1,575

1,753

14,680

1,842

19,212

(5,206)

(6,146)

6,728

(326)

9,469

2,250

–

5,929

–

1,374

–

6,756

946

–

5,433

941

–

(6,121)

(5,777)

–

–

–

–

–

(3)

62

–

–

–

–

–

–

–

(12)

82

–

–

(2,600)

(2,800)

44,919

46,405

(960)

(2,133)

Profit for the year

Taxation

Interest payable and  
similar charges

Interest income

Foreign exchange (gain)/loss

Loss on disposal of intangibles

Depreciation of property, plant  
and equipment 

Amortisation and impairment  
of intangibles

Change in inventories

Change in trade and  
other receivables

Change in trade and  
other payables

Change in provisions

Share-based employee 
remuneration

Dividends received

Cash generated from/ 
(used in) operations

26. Capital commitments
The Group had capital commitments at 31 December 2021 totalling £Nil  
(2020: £3,500,000). 

27. Contingent liabilities
Contingent liabilities are possible obligations that are not probable. The Group operates 
in a highly regulated sector and in markets and geographies around the world each with 
differing requirements. As a result, and in the normal course of business, the Group can be 
subject to a number of regulatory inspections/investigations/customer and other claims on an 
ongoing basis. It is therefore possible that the Group may incur penalties for non-compliance. 
In addition, a number of the Group’s brands and products are subject to pricing and other 
forms of legal or regulatory restrictions from both governmental/regulatory bodies and also 
from third parties. Assessments as to whether or not to recognise a provision in respect of 
these matters are judgemental as the matters are often complex and rely on estimates and 
assumptions as to future events.

28. Pensions
The Group operates a defined contribution pension scheme for the benefit of Executive 
Directors and certain employees. 

The Group

31 December 2021
£000s

31 December 2020
£000s

Contributions payable by the Group for the year

1,306

994

134

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

29. Related party transactions 
During the year, the Company entered into the following transactions with related parties:

The Company 
Transaction values for the year ended 

Amount due from 
related parties 

31 December 2021
£000s

31 December 2020
£000s

31 December 2021
£000s

31 December 2020
£000s

Alliance Pharmaceuticals 
Limited – Net funds received

Alliance Pharmaceuticals 
Limited – Interest received 

Alliance Pharmaceuticals 
Limited – Investments during 
the year 

Alliance Pharmaceuticals 
Limited – Share-based 
payment recharge 

Alliance Pharmaceuticals 
Limited – Dividend declared 
and received 

(10,170) 

750

176,111

176,539

6,121 

5,777

– 

(272)

1,021

1,109

2,600 

2,800

–

–

–

–

–

–

–

–

Net funds received represent net payments made against the intercompany loan by Alliance 
Pharmaceuticals Limited.

30. Joint ventures

Name

Principal activity

Country of 
incorporation

% 
Owned

Synthasia International Company Limited Distribution of infant milk formula 

Hong Kong

products in China

Synthasia Shanghai Company Limited

Distribution of infant milk formula 
products in China

China

20

20

Until 10 March 2021, the Group owned 20% of the issued share capital of Synthasia 
International Company Limited, which is a 100% parent of Synthasia Shanghai Company 
Limited (together known as ‘Synthasia’). The Group considered the existence of substantive 
participating rights held by both the Group and another shareholder which provide both 
parties with a veto right over the significant financial and operating policies of Synthasia 
and determined that, as a result of these rights and by exercise of judgement, Synthasia was 
accounted for as a joint venture. In accordance with IFRS 11 Joint Arrangements, a joint 
venturer shall recognise its interest in a joint venture as an investment and shall account for that 
investment using the equity method in accordance with IAS 28 Investments in Associates and 
Joint Ventures. 

In May 2018 the Group was notified that the import licence partner was not going to 
receive the required approval to import Suprememil, the infant milk formula brand owned by 
Synthasia. Following subsequent discussions with the import licence partner and Synthasia 
management, the Board concluded that the joint venture investment of £0.3m, and associated 
loan balances of £2.2m, was to be written down in full. 

Following the impairment further losses from the Synthasia joint venture have not been 
recognised. This is due to the Group having no obligation to fund such losses. 

On 10 March 2021 the Group fully divested its holding in Synthasia for nil consideration.  
As part of the terms of disposal Suprememil brand trademarks were retained by the Group  
for potential future use. There are currently no forecasted sales for this brand.

31. Acquisition of Biogix Inc
On 29 December 2020 the Group completed the acquisition of 100% of the share capital 
of Biogix Inc, a privately held, US-based consumer healthcare company. The acquisition 
brought into the Group a highly successful and fast-growing brand, Amberen, with significant 
near-term growth potential.

The total amount paid in relation to the acquisition was $111.3m, being $110.0m consideration 
paid in cash on completion, $0.4m estimated working capital adjustment paid in cash on 
completion and $0.9m foreign exchange option cash premium paid in December 2020.

135

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

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Financial Statements

Additional Information

31. Acquisition of Biogix Inc continued

The acquisition was funded by drawdown of $22.0m and £66.1m from the Group’s existing 
£165m Revolving Credit Facility shortly before completion in December 2020. The Sterling 
drawdown was subsequently sold in a foreign exchange transaction to buy US Dollars for use 
in settlement of cash payments on completion. A portion of funding was drawn in Sterling so 
that, after taking account of existing borrowings, the Group’s overall loan position by currency 
matches expected post-hedging cash generated by currency. 

The fair value of the intangible asset recognised on business combination all relates to 
Amberen. A single brand intangible asset was identified for valuation through completion of 
a formal purchase price allocation exercise. This brand recognition and positioning were the 
key drivers for the acquisition and are regarded as the main barrier to market entry. No other 
intangible assets were considered to have separately identifiable value. 

The brand was valued using a multi-period excess earnings approach, utilising the Group’s 
long-term cash flow forecast and a post-tax discount rate of 10.75%.

The fair values of the assets acquired, as at 29 December 2020, are as follows:

None of the goodwill recognised is expected to be deductible for income tax purposes.

Book value  
of assets and 
liabilities acquired  
$000s

37
223

419

5,824
382
(1,587)
(378)
4,920

Intangible fixed assets
Deferred tax asset
Property, plant  
and equipment
Current assets (excluding 
cash and cash equivalents)
Cash and cash equivalents
Current liabilities
Lease liabilities
Net assets 
Deferred tax liability
Goodwill
Fair value of net  
assets acquired
Cash consideration
Working capital adjustment 
paid in cash
Option premium paid in cash
Total consideration

Fair value 
adjustments  
$000s

121,000
–

Fair value of  
assets and  
liabilities acquired  
$000s

Fair value of  
assets and  
liabilities acquired  
£000s

121,037
223

–

419

–
–
–
–
121,000

5,824
382
(1,587)
(378)
125,920
(35,101)
20,501

111,320
110,000

411
909
111,320

89,990
166

312

4,330
284
(1,180)
(281)
93,621
(26,097)
15,244

82,768
81,784

308
676
82,768

The fair values set out above are final figures, following additional review of judgemental areas 
including intangible asset allocation and finalisation of completion accounts during the year. 
There was a reduction in the working capital adjustment paid in cash by $249,000 (£183,000). 

Legal and professional fees incurred in the acquisition of £1.3m were recognised as non-
underlying costs within administration and marketing expenses (note 5). 

32. Events after the reporting date
On 25 March 2022 the Group announced that it has completed the acquisition of the Kelo-
cote® US licensing rights and the second largest US scar treatment brand ‘ScarAway®’ from 
Perrigo Company PLC, a global consumer self-care company, for $19.4m (£14.8m). paid for 
in cash from the Group’s existing financial resources. The accounting considerations will be 
finalised in the second quarter of 2022 and included in the Group’s interim results for the six 
months ended 30 June 2022.

33. Ultimate controlling party
The Company’s shares are listed on the Alternative Investment Market (‘AIM’) and are held 
widely. There is no single ultimate controlling party.

34. Alternative performance measures
The performance of the Group is assessed using Alternative Performance Measures (‘APMs’). 
The Group’s results are presented both before and after non-underlying items. Adjusted 
profitability measures are presented excluding non-underlying items as we believe this 
provides both management and investors with useful additional information about the Group’s 
performance and aids a more effective comparison of the Group’s trading performance from 
one period to the next and with similar businesses. In addition, the Group’s results are described 
using certain other measures that are not defined under IFRS and are therefore considered to 
be APMs. These measures are used by management to monitor ongoing business performance 
against both shorter-term budgets and forecasts but also against the Group’s longer-term 
strategic plans. APMs used to explain and monitor Group performance are as follows:

136

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

34. Alternative performance measures continued

A. Underlying EBIT and EBITDA

Measure

Definition

Underlying 
EBIT and 
EBITDA

Earnings before interest, tax and non-underlying items (EBIT, also referred to 
as underlying operating profit), then depreciation, amortisation and underlying 
impairment (EBITDA).

Reconciliation 
to GAAP measure

Note A below

Calculated by taking profit before tax and financing costs, excluding  
non-underlying items and adding back depreciation and amortisation.

EBITDA margin is calculated using see-though revenue.

Free cash 
flow

Free cash flow is defined as cash generated from operations less cash payments 
made for interest payable and similar charges, capital expenditure and tax.

Note B below

Reconciliation of Underlying EBIT and EBITDA

Profit before tax 

Non-underlying items (note 5)

Underlying profit before tax

Finance costs (note 6)

Underlying EBIT

Depreciation (note 12)

Underlying amortisation (note 11)

Net debt

Net debt is defined as the Group’s gross bank debt position net of finance issue 
costs and cash.

Underlying  
effective tax 
rate 

Underlying effective tax rate is calculated by dividing total taxation for the year 
less impact of tax rate changes and non-underlying charges, by the underlying 
profit before tax for the year.

See-through
Income 
Statement

Under the terms of the transitional services agreement with certain supply partners, 
Alliance receives the benefit of the net profit on sales of Nizoral from the date of 
acquisition up until the product licences in the Asia-Pacific territories transfer to 
Alliance. The net product margin is recognised as part of statutory revenue.

Constant 
exchange 
rate (CER) 
revenue

Like-for-like

The see-through Income Statement recognises the underlying sales and cost of 
sales which give rise to the net product margin, as management consider this 
to be a more meaningful representation of the underlying performance of the 
business, and to reflect the way in which it is managed.

Like-for-like revenue, impact of acquisitions, and total see-through revenue are 
stated so that the portion denominated in non-Sterling currencies is retranslated 
using foreign exchange rates from the previous financial year.

Like-for-like figures compare financial results in one period with those for the 
previous period, excluding the impact of acquisitions and disposals made in 
either period. For 2021, like-for-like revenue excludes the impact of Amberen 
which was acquired in December 2020.

Note C below

Underlying EBITDA

Note D below

B. Free cash flow

Note E below

Reconciliation of free cash flow

Cash generated from operations (note 25)

Interest payable and similar charges

Capital expenditure

Tax paid

Free cash flow

Note F below

C. Net debt

Reconciliation of net debt

Not needed

Loans and borrowings – non-current

Cash and cash equivalents

Net debt

Operating 
costs

Defined as underlying administration and marketing expenses, excluding 
depreciation and underlying amortisation charges.

Not needed

Year ended  
31 December 2021
£000s

Year ended  
31 December 2020
£000s

18,157

24,061

42,218

3,418

45,636

1,575

1,362

48,573

13,016

20,512

33,528

3,300

36,828

1,753

–

38,581

Year ended  
31 December 2021
£000s

Year ended  
31 December 2020
£000s

44,919 

(2,965)

(5,532)

(6,260)

30,162

46,405

(2,866)

(4,612)

(4,838)

34,089

Note

18

16

31 December 2021
£000s

31 December 2020
£000s

(116,060)

29,061 

(86,999)

(138,328)

28,898

(109,430)

137

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

34. Alternative performance measures continued
D. Underlying effective tax rate

There is no impact from the see-through adjustment on Income Statement lines below 
gross profit. 

Reconciliation of underlying effective tax rate

Total taxation charge for the year

Non-underlying tax debit/(credit) (note 5)

Underlying taxation charge for the year 

Underlying profit before tax for the year

Underlying effective tax rate

E. See-through Income Statement

Revenue – Consumer Healthcare brands

Revenue – Prescription Medicines

Total revenue 

Cost of sales

Gross profit

Gross profit margin

Revenue – Consumer Healthcare brands

Revenue – Prescription Medicines

Total revenue 

Cost of sales

Gross profit

Gross profit margin

Year ended  
31 December 2021
£000s

Year ended  
31 December 2020
£000s

F. Constant exchange rate revenue

(10,838)

2,805

(8,033)

42,218

19.0%

See-through  
adjustment 
£000s

6,443

–

6,443

(6,443)

–

–

See-through  
adjustment 
£000s

7,719

–

7,719

(7,719)

–

–

(4,989)

(1,383)

(6,372)

33,528

19.0%

2021  
See-through  
values
 £000s

121,819 

47,831 

169,650

(60,200)

109,450

64.5%

2020  
See-through  
values
 £000s

93,059

44,461

137,520

(54,704)

82,816

60.2%

2021  
Statutory 
 values 
£000s

115,376 

47,831 

163,207

(53,757)

109,450

67.1%

2020  
Statutory 
 values 
£000s

85,340

44,461

129,801

(46,985)

82,816

63.8%

LFL see-through revenue – Consumer  
Healthcare brands

LFL see-through revenue – Prescription Medicines

Like-for-like see-through revenue

Impact of acquisitions (Amberen)

See-through revenue (Note E)

LFL statutory revenue – Consumer  
Healthcare brands

LFL statutory revenue – Prescription Medicines

Like-for-like statutory revenue

Impact of acquisitions (Amberen)

Statutory revenue

2021 
AER
£000s

102,586

47,831

150,417

19,233

169,650

2021 
AER
£000s

96,143

47,831

143,974

19,233

163,207

Foreign  
exchange  
impact 
£000s

3,389

326

3,715

1,362

5,077

Foreign  
exchange  
impact 
£000s

3,247

326

3,573

1,362

4,935

2021  
CER 
 £000s

105,975

48,157

154,132

20,595

174,727

2021  
CER 
 £000s

99,390

48,157

147,547

20,595

168,142

138

Notes to the Financial Statements continuedAlliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Additional Information

Unaudited Information

Shareholder Information
Shareholder enquiries
The Company’s share register is maintained by Link Group (‘Link’) who are responsible 
for updating the register, including changes to shareholders’ names or addresses and 
processing off-market transfers of the Company’s shares. If you have any question about your 
shareholding in the Company or you need to notify any changes to your personal details you 
should write to Link Group, 10th Floor, Central Square, 29 Wellington Street, Leeds, LS1 4DL 
or telephone 0371 664 0300 (calls are charged at the standard geographical rate and will 
vary by provider, lines are open 9.00am to 5.00pm Monday to Friday). 

Financial Calendar
Annual General Meeting 

18 May 2022

Interim results announcement 

20 September 2022

Year end 

31 December 2022

Preliminary announcement 

21 March 2023

139

Alliance Pharma plc – Annual Report and Accounts 2021 
 
 
 
Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Additional Information continued

Five Year Summary

Revenue

Operating profit before non-underlying items

Non-underlying operating items

Operating profit 

Profit before tax before non-underlying items

Profit before tax after non-underlying items

Intangible assets

Tangible assets

Current assets

Current liabilities

Equity

Average shares in issue (millions)

Shares in issue at period end (millions)

Earnings per share – basic (p)

Earnings per share – adjusted underlying basic (p)

Year ended 
 31 December 2017
£m

Year ended 
 31 December 2018
£m 

Year ended 
 31 December 2019
£m

Year ended 
 31 December 2020
£m

Year ended 
 31 December 2021
£m

101.6

25.8

4.4

30.2

23.9

28.3

278.6

5.7

49.1

61.4

203.1

473.8

475.0

6.08

4.05

118.2

28.9

(5.3)

23.7

28.1

22.8

335.2

7.6

58.7

91.7

252.2

497.2

518.2

3.69

4.54

135.6

37.4

(1.8)

35.6

32.9

31.1

328.7

11.6

65.0

24.2

274.2

520.7

529.4

4.80

5.09

129.8

36.8

(20.5)

16.3

33.5

13.0

412.9

15.9

77.2

30.2

281.0

531.1

532.9

1.51

5.11

163.2

45.6

(24.0)

21.6

42.2

18.2

413.8

4.8

81.0

40.6

282.5

535.3

538.2

1.37

6.39

140

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Additional Information continued

Advisers and Key Service Providers

Registered Office
Avonbridge House 
Bath Road 
Chippenham 
Wiltshire 
SN15 2BB

Company number
04241478

Auditor
KPMG LLP
66 Queen Square 
Bristol  
BS1 4BE

Financial PR
Buchanan Communications
107 Cheapside 
London  
EC2V 6DN

Registrars
Link Group
10th Floor 
Central Square 
29 Wellington Street 
Leeds 
LS1 4DL

Nomad and Joint Broker
Numis Securities Limited
45 Gresham Street 
London  
EC2V 7BF

Joint Broker
Investec Bank plc
2 Gresham Street 
London 
EC2V 7QP

Bankers
Bank of Ireland
Bows Bells House 
1 Bread Street 
London EC4M 9BE

Citibank, N.A
Citigroup Centre 
33 Canada Square 
Canary Wharf 
London E14 5LB

Lloyds Bank PLC
25 Gresham Street 
London EC2V 7HN

National Westminster Bank PLC
250 Bishopsgate 
London EC2M 4AA

Silicon Valley Bank
Alphabeta 
14–18 Finsbury Square 
London EC2A 1BR

141

Alliance Pharma plc – Annual Report and Accounts 2021Company Overview

Strategic Report

Governance

Financial Statements

Additional Information

Additional Information continued

Cautionary Statement 

Glossary

The Report of the Directors in this Annual 
Report has been drawn up and presented in 
accordance with English company law and 
the liabilities of the Directors in connection 
with that report shall be subject to the 
limitations and restrictions provided by  
such law. 

In particular, Directors would be liable to the 
Company (but not to any third party) if the 
Report of the Directors contains errors as a 
result of recklessness or knowing misstatement 
or dishonest concealment of a material fact, 
but would not otherwise be liable.

Cautionary statement regarding 
forward-looking statements
This Annual Report has been prepared for the 
members of the Company and no one else. 
The Company, its Directors, employees or 
agents do not accept or assume responsibility 
to any other person in connection with this 
document and any such responsibility or 
liability is expressly disclaimed.

This Annual Report contains certain 
forward-looking statements with respect to 
the principal risks and uncertainties facing 
Alliance. By their nature, these statements 
and forecasts involve risk and uncertainty 
because they relate to events and depend on 
circumstances that may or may not occur in 
the future. There are a number of factors that 
could cause actual results or developments 
to differ materially from those expressed 
or implied by these forward-looking 
statements and forecasts. The forward-
looking statements reflect the knowledge 
and information available at the date of 
preparation of this Annual Report, and will 
not be updated during the year. Nothing in 
this Annual Report should be construed as a 
profit forecast.

ABHI

ABPI

AGM

CBEC

CEO

CFO

CMA

CMO

ERP

ESG

FDA

FTC

HCP

IHP

J&J

LSP

NAD

OTC

PAGB

QPPV

SECR

S&OP

TCFD

VPAS

Association of the British HealthTech Industry

Association of the British Pharmaceutical Industry

Annual General Meeting

Cross Border E-Commerce

Chief Executive Officer

Chief Finance Officer

Competition and Markets Authority

Contract Manufacturer

Enterprise Resource Planning

Environmental, Social, and Governance

US Food and Drug Administration

Federal Trade Commission

Healthcare Professional

International Health Partners

Johnson and Johnson

Logistics Service Provider

National Advertising Division

Over the Counter

Proprietary Association of Great Britain

Qualified Person Responsible For Pharmacovigilance

Streamlined Energy and Carbon Reporting regulations

Sales and Operations Planning

Task Force on Climate-related Financial Disclosures

Voluntary Pricing and Access Scheme

142

Alliance Pharma plc – Annual Report and Accounts 2021CBP00019082504183028

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Alliance Pharma plc 

Avonbridge House, Bath Road, Chippenham, Wiltshire, SN15 2BB, United Kingdom 
T: +44 (0)1249 466966 F: +44 (0)1249 466977 E: ir@alliancepharmaceuticals.com  
www.alliancepharmaceuticals.com