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OptiBiotix Health Plc

opti · LSE Consumer Cyclical
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FY2018 Annual Report · OptiBiotix Health Plc
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ANNUAL REPORT AND ACCOUNTS 

FOR THE YEAR ENDED 30 NOVEMBER 2018

Contents 

Company Information

Chairman’s and Chief Executive’s  
Statement

Strategic Report

Directors’ Report

Report of the Independent Auditors

Consolidated Statement of  
Comprehensive Income

Consolidated Statement of 
Financial Position

Consolidated Statement of  
Changes in Equity

Consolidated Statement of  
Cash Flows

Notes to the Consolidated  
Statements of Cash Flows

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Company Statement of 
Financial Position

Company Statement of  
Changes in Equity

Company Statement of Cash Flows

Notes to the Company  
Statements of Cash Flows

Notes to the Financial Statements

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1

OptiBiotix Health Plc 

 
 
 
Company Information 

Directors:                                                                                                 S P O’Hara  
                                                                                                                      G Barker  
                                                                                                                      P Wennström 
                                                                                                                      C Wood  
                                                                                                                      R Davidson 
                                                                                                                      M Christie 
                                                                                                                      S Kolyda 
                                                                                                                      F Narbel 

Secretary:                                                                                                 International Registrars Limited 

Registered number:                                                                             05880755 (England & Wales) 

Registered office:                                                                                  Innovation Centre 
                                                                                                                      Innovation Way 
                                                                                                                      York 
                                                                                                                      YO10 5DG 

Auditors:                                                                                                   Jeffreys Henry LLP 
                                                                                                                      Finsgate 
                                                                                                                      5-7 Cranwood Street 
                                                                                                                      London 
                                                                                                                      EC1V 9EE 

Nominated adviser:                                                                             Cairn Financial Advisers LLP 
                                                                                                                      Cheyne House 
                                                                                                                      Crown Court 
                                                                                                                      62-63 Cheapside 
                                                                                                                      London  
                                                                                                                      EC2V 6AX 

Brokers:                                                                                                    finnCap 
                                                                                                                      60 New Broad street 
                                                                                                                      London 
                                                                                                                      EC2M 1JJ 

Website Address:                                                                                  www.optibiotix.com  

Annual Report and Accounts 2018  2

Market Context

The human microbiome are collectively the trillions of microorganisms which lives 
in and on our bodies and which play a vital part in our health. The awareness and 
scientific evidence of the microbiome and its relationship to human health and 
disease has grown in the last few years and now attracts much interest from global 
pharmaceutical  and  biotechnology  industries.  Strong  evidence  of  the  growing 
interest is the rapidly growing number of scientific publications in the field from 
Europe, the USA, and more recently China. 

Life sciences companies are showing growing interest in the microbiome to harness 
the power of developing non-pharmaceutical solutions for health problems. It is 
estimated that by 2025Microbiome development opportunities will be worth close 
to a trillion dollars with estimated growth (2022-2025) of 22.3% CAGR (Source: Market 
& Markets January 2016). 

Europe  is  expected  to  account  for  the  largest  total  share  mainly  through  its 
significant presence in the probiotics and prebiotics fields and the acceptance of 
these  products  by  the  consumer.  For  probiotics  the  global  retail  value  was 
USD40 billion in 2016. For probiotic supplements the retail value was USD4.3 billion 
in 2016 with a 38% growth prediction to 2021, whilst the US market retail value of 
probiotic supplements is expected to grow by 55% (2016-2021) to USD3.3 billion. 
(Source: Euromonitor International June 2017). 

The OptiBiotix Difference 

•       Utilises  validated  technology  platforms 
which  reduce  the  risk  of  developing 
products which modify the microbiome 
and improve health 

•       Extensive  and  valuable  IP  portfolio  of 
90+ patents and 40+ trademarks, 

•       Commercial  partners  in  place  for  all 

platforms with global brands  

•       At the forefront in the development of 
microbiome products which enable next 
generation health solutions 

•       Enables  current  brands  to  renovate 
products and price levels and new brands 
to  innovate  with  new  differentiated 
solutions 

According to the “Global Nutrition report 2017” more the 2 billion adults (age 18+) in the world are overweight or considered obese. It is today one 
of the world’s biggest public health problems increasing the risk of chronic diseases including diabetes, cardiovascular diseases, fatty liver, some 
cancers and immune-related diseases with an estimated cost to the global economy of USD1.2 trillion annual by 2025.In the UK, the bill is set to 
rise from USD19 billion to USD31 billion per year in 2025. (Source: The Guardian, October 2017). 

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OptiBiotix Health PLC is a leading company in the field of microbiome product research and development. We are developing the next generation 
of microbial strains (LPLDL®), targeted prebiotics (LPGOS), sweet functional fibres (SweetBiotix®), compounds and formulations (SlimBiome®) which 
modulate the human microbiome and impact on lipid and cholesterol management, energy harvest and appetite suppression, fuelled by our 
proprietary development and technology platforms to bring potential health benefits.  

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3

OptiBiotix Health Plc 

 
 
Overview of OptiBiotix

Key highlights of the year 

December  –  The  appointment  of  Neil  Davidson  CBE  as  Non 
executive chairman bringing sector specific commercial expertise 
and a track record of building shareholder value 

June – Non-exclusive agreement with global dairy company to 
explore the use of SweetBiotix® calorie free sweet fibres in dairy 
food products.  

February – Presentation of research at an international 
conference (ProBiota 2018) with DSM, on the development of a 
prebiotic which selectively enhances the growth of 
Lactobacillus rhamnosus GG (“LGG®”)  

April – Exclusive agreement with Trigen Pharma to 
commercialise OptiBiotix’s own label CholBiome® products 
in Pakistan. 

May – Exclusive agreement with Akums Drugs and 
Pharmaceuticals to exclusively manufacture and supply 
products containing LPLDL®, in India. 

May – SlimBiome® wins award for Weight Management 
Ingredient of the Year at the Vitafoods European tradeshow in 
Geneva. 

May – LPLDL® non exclusive agreement with Seed Health to 
commercialise products containing LP-LDL® in the USA.

June – Exclusive license agreement with ALFASIGMA to 
commercialise food supplements containing LPLDL® in Italy.  

June – Exclusivity with global corporate for the scale up and 
manufacture of SweetBiotix®  

September – Exclusive agreement with a US company for LPLDL® 
as a drug product with 6 figure milestone payments 

October  –  Non  exclusive  distribution  agreement  with  CTC 
Holding  to  distribute  SlimBiome®  weight  in  the  Philippines, 
Vietnam, Indonesia and Colombia. 

November – SlimBiome® receives CE mark and approval as a 
medical device.  

December  –  Exclusive  distribution  for  SlimBiome®  Medical  in 
Greece and Cyprus.  

December  –  Appointment  of  Dr  Fred  Narbel  as  Managing 
Director of OptiBiotix’s prebiotic division

Annual Report and Accounts 2018  4

 
Over the last year OptiBiotix has moved its Probiotic and OptiBiome divisions 
forward to commercialise their products i.e. Cholesterol and blood pressure 
reducing LPLDL® strain and its weight management ingredient SlimBiome® which 
were both launched at the VitaFoods tradeshow in Geneva may 2017. As part of the 
commercialisation process OptiBiotix has been focusing on getting the right 
partners in place for the manufacturing of the active ingredients and partners for 
the final product applications to be able to supply into distribution partners. 
OptiBiotix has achieved media and industry attention which has strengthened the 
commercial development of its products leading to a significant number of 
commercial agreements. 

Brief outlook on 2019: 

The focus for 2019 is on reaching new agreements, ensuring existing agreements generate revenues for SlimBiome® and LPLDL® and extending 
commercial reach further into the US and Asia. With the fast maturing Probiotics division we see a large potential in developing the 
manufacturing of the LPLDL® strain suitable for the pharmaceutical area. 

SweetBiotix® is progressing really well scientifically and is looking to offer a number of technology platforms which are now maturing into 
multiple opportunities across a wide range of application areas with a number of large corporates both on manufacturing and application 
development. 

We have achieved a number of scientific awards for our science at ProBiota and wonweight Management of the Year fro SlimBiome at 
Viafoods 2018. 

“Rewarding true innovation and cutting edge research in healthy foods, supplements and nutrition”

5

OptiBiotix Health Plc 

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OptiBiotix Deal Pipeline 

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Annual Report and Accounts 2018  6

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Chairman’s and Chief Executive’s Statement 

We  are  pleased  to  present  OptiBiotix 
the 
Health  plc’s 
and 
“Company”) 
accounts 
ended 
30 November 2018. 

(“Optibiotix”  or 
report 
annual 
year 
the 

for 

The 12 months to 30 November 2018 
have seen the continued transition of 
the  Company  from  a  research  and 
development business to a company 
showing strong commercial traction for 
its award winning products and technologies with significant deal flow 
and  rapidly  growing  revenues.  This  period  has  seen  eighteen 
commercial agreements signed in the year to 30 November 2018, eight 
more  than  the  10  deals  concluded  in  2017.  OptiBiotix  has  now 
completed twenty eight deals reflecting international interest from 
industry in high value ingredients and products which have a strong 
scientific and clinical evidence base. Of these deals approximately 20% 
are with companies whose annual turnover is greater than one billion 
dollars, and represent an opportunity to access global markets with 
large corporate partners.  

As the year progressed, an increasing number of agreements started to 
generate income with revenue growth in the second half of the year 
significantly  higher  than  at  the  start  of  the  year.  As  existing  deals 
contribute to full year revenues, partners continue to grow sales with 
new product launches in 2019, and new agreements continue to be 
signed on a regular basis, we anticipate further revenue growth in 2019.  

Key to OptiBiotix’s success is its strong science, independent clinical 
studies, and key opinion leader endorsement. Whilst each product has 
a different technological base they are united by a common theme of:- 

•

•

•

Understanding the underlying science and mechanism of 
action in laboratory studies. This allows us to optimise our 
products and identify multiple application opportunities. 

Proving our products are safe and that they work in humans 
by carrying out independent clinical studies and publishing 
them in leading peer reviewed journals authored by leading 
academics respected by industry. 

Working with world leading key opinion leaders who support 
the science behind our products. 

This systematic approach has led to OptiBiotix’s science winning awards 
at  international  conferences  (ProBiota  2017  and  2018)  and  its  two 
products,  LPLDL  and  SlimBiome®,  being  nominated  for  awards,  with 
SlimBiome® winning the award for best weight management ingredient 
at  Food  Matters  in  November  2017,  and Vitafoods  in  May  2018.  Of 
particular note in 2018 was the award for best scientific abstract at 
ProBiota  with  co-authors  DSM  for  developing  a  prebiotic  which 
selectively increased the growth rate of DSM”s Lactobacillus rhamnosus 
GG (LGG®), contained within its Culturelle® range. We believe this is the 

777

OptiBiotix Health Plc 

first reported publication of an optimised prebiotic for LGG®, one of the 
world’s best-selling probiotics. We see the combination of a probiotic 
and a prebiotic, which selectively enhances the probiotics growth and 
functionality, creates a means to provide product differentiation and 
enhance the benefits of existing probiotic products in the market. We 
anticipate further commercial progress in this area in 2019. 

We were also pleased by results of a clinical study carried out by the 
University of Roehampton which demonstrated that human volunteers 
taking SlimBiome® had statistically significant reductions in weight, BMI, 
hip circumference, percentage body fat, fat mass and systolic blood 
pressure (P<0.01) after four weeks of SlimBiome® intake. Significant 
reductions  in  cravings  for  savoury  foods  (P<0.001)  and  a  trend  for 
reduced sweet cravings were recorded from the end of week one of the 
treatment  onwards,  accompanied  by  a  significant  improvement  in 
mood  (P<0.01). This  study  added  further  evidence  to  other  clinical 
studies  and  consumer  feedback  which  shows  SlimBiome®  has  a 
significant impact on food cravings and hunger, leading to easier and 
more successful weight loss, typically 2-3lbs per week.  

We  believe  this  strategy  of  investing  in  strong  science  and  clinical 
studies, which independently demonstrate the safety and efficacy of 
our products, provides clear product differentiation and stimulates high 
industry interest, leading to strong deal flow. As the Company continues 
its transition from a technology company to a product company, it will 
continue  to  carry  out  further  studies  and  present  its  science  at 
international conferences and in leading peer reviewed journals around 
the world.  

Of particular note in the last year is the recognition of this systematic 
approach from pharmaceutical companies who have signed deals to 
develop LPLDL® as a drug product, and the award of medical device 
status and CE mark for SlimBiome®. These represent significant value 
enhancing steps as they extend the commercial opportunities for LPLDL® 
and  SlimBiome® 
into  the  high  value  medical  products  and 
pharmaceutical drug markets. 

As  the  scientific  and  consumer  understanding  of  the  role  of  the 
microbiome in the prevention of disease and the maintenance of health 
grows we see substantial opportunities in international markets for our 
products.  We  look  forward  to  converting  this  interest  into  growing 
revenue  streams  from  license  deals  and  supply  agreements  in  the 
months and years ahead. 

During the period to date we have achieved a number of key objectives, 
which continue to build shareholder value. These include:- 

•

•

A US manufacturing, supply and profit sharing agreement 
with Cereal Ingredients, Inc for SlimBiome®. 

Completion  of  five  successful  human  taste  studies  on 
SweetBiotix®  demonstrating  high  sweetness  and  low  off 
flavours.  

 
•

•

•

•

•

•

•

•

•

•

•

•

•

A  five  year  distribution  agreement  with  Trigen  Pharma 
International  to  exclusively  distribute  and  commercialise 
OptiBiotix’s own label CholBiome® products in Pakistan. 

A  non-exclusive  distribution  agreement  with  Cambridge 
Commodities  Ltd 
to  distribute  SlimBiome®  weight 
management technology in the United Kingdom. 

A  five  year  agreement  with  Akums  Drugs  and 
Pharmaceuticals Ltd to exclusively manufacture and supply 
supplements and biotherapeutic drug products containing 
LPLDL® in India. 

A non exclusive agreement with Seed Health to produce, 
promote, market, and commercialise products containing 
LPLDL® in the USA. 

A  non-exclusive  license  with  one  of  the  world’s  largest 
providers of dairy products to explore the potential for using 
OptiBiotix’s  SweetBiotix®  technology  to  reduce  the  sugar 
content in a range of its dairy food products. 

the 
Exclusive  agreement  with  a  US  company 
development of LPLDL® as a drug product with a six figure 
milestone  payments  at  signing  and  at  two  subsequent 
conditional milestones, amounts totalling a seven-figure sum. 

for 

Exclusive license agreement with AlfaSigma to commercialise 
food supplements containing LPLDL® in Italy. 

Non exclusive distribution agreement with CTC Holding to 
distribute SlimBiome® in the Philippines, Vietnam, Indonesia 
and Colombia. 

Launch of OptiBiotix online selling own brand GoFigure® and 
CholBiome®  products  direct  to  market  providing  a  shop 
window for its LPLDL® and SlimBiome® technologies.  

Award for SlimBiome® for Weight Management Ingredient of 
the Year at Vitafoods 2018 and ‘Best Functional Ingredient for 
Health and Wellbeing’ at Food Matters.  

for  best  scientific  abstract  at  ProBiota  2018 
Award 
co-authored  with  DSM 
identification  and 
for 
development of a prebiotic which selectively enhances the 
growth of Lactobacillus rhamnosus GG (“LGG®”) in the gut.  

the 

Independent  human  studies  from  by  Oxford  Brookes 
University  demonstrating  that  volunteers  who  took 
SlimBiome® compared to a placebo feel fuller and are less 
hungry, have less food cravings, and eat less sweet and fatty 
foods. 

The  granting  of  medical  device  status  and  a  CE  mark  for 
SlimBiome® extending its application as a food ingredient 

into high value medical products within consumer healthcare 
and pharmaceutical markets.  

The  appointment  of  Neil  Davidson  as  Non-Executive 
Chairman bringing sector expertise, a network of industry 
contacts,  and  over  30  years  of  operational  and  Board 
experience as Chairman, Chief Executive and Director of FTSE 
100, AIM and private companies. 

The investment in OptiBiotix of £450k by new non executive 
board members Neil Davidson and Sean Christie. 

•

•

Strategy 

OptiBiotix’s strategy is to develop microbiome product with a scientific 
and clinical evidence base targeted at large markets (>£100 million) 
where there are high growth opportunities (CAGR >10%), and a large 
unmet  demand.  Given  the  evolving  nature  of  the  microbiome 
OptiBiotix’s approach has been designed to reduce investor risk by 
building multiple opportunities within the microbiome space across a 
number of platforms which create food ingredients, supplements and 
pharmaceutical  products  with  partners.  This  multi  partner, 
multi-channel approach, enables OptiBiotix to maximize the income 
potential  of  each  product,  whilst  limiting  the  risk  related  to  any 
individual deal. This is reflected in OptiBiotix’s deal structure in which 
approximately 20% of deals are with companies whose annual turnover 
greater than one billion dollars, and the remaining 80% are with small 
to medium size companies who are quicker to market. Common to 
each  partner  is  an  existing  industry  reputation  and  an  established 
distribution network within the target market. 

This allows OptiBiotix to operate on a very asset-light infrastructure with 
manufacturing,  regulatory  approvals,  and  sales  and  marketing 
infrastructure funded by OptiBiotix’s partners such that license and 
royalty fees are largely cost free. Whilst this strategy takes longer to 
develop than single license deals it is a low risk, low cost approach to 
accessing multiple consumer healthcare and pharmaceutical markets 
around the world, and if successful, has the potential to cumulatively 
generate  substantive  revenues  and  profitability  in  the  forthcoming 
years. 

The  large  number  of  agreements  signed  in  2018  across  multiple 
application  areas  represents  early  execution  of  this  strategy. These 
agreements are starting to generate recurrent revenue streams and will 
form  the  backbone  of  future  sales  growth.  We  anticipate  further 
execution of this strategy in 2019 with growing revenues against a 
continued low-cost base creating profitable divisions across all areas of 
the Company. 

In  April  2017,  OptiBiotix’s  majority  owned  skincare  subsidiary, 
SkinBiotherapeutics (formerly SkinBiotix), was admitted to AIM with an 
associated  £4.5  million  institutional  and  private  client  investment 
manager fundraise. SkinBiotherapeutics plc is making solid progress in 

Annual Report and Accounts 2018  8

industry  validation  of 

building relationships with potential commercial partners, successfully 
completing human studies, and building a commercial leadership team. 
As  its  partnership  discussions  turn  into  commercial  agreements 
providing 
its  technology  we  anticipate 
SkinBiotherapeutics  plc  will  grow  in  value  whereupon  OptiBiotix 
shareholders will benefit from the appreciation of this asset. This is an 
innovative business model which over time looks to give OptiBiotix 
shareholders a position in multiple separately listed companies, and with 
it the prospect of multiple returns. 

As part of this strategy OptiBiotix raised £1.025 million through the issue 
of  convertible  loan  notes  for  its  wholly  owned  subsidiary  ProBiotix 
Health  Limited.  The  funds  will  be  used  to  provide  funding  for  an 
independent exit or potential initial public offering of ProBiotix in the 
UK, Europe, or the US, depending on market conditions. This is in line 
with OptiBiotix’s strategy to form separate divisions, which could in due 
course become separate legal entities with the potential for a separate 
public listing.  

Commercial 

The last twelve months has seen the continued transition of OptiBiotix® 
from a research and development Company to a commercial business 
with the signing of eighteen agreements with products now being 
commercialised  in  over  thirty  countries. This  includes  a  number  of 
agreements  with  leading  manufacturing  partners  within  India.  This 
introduces local manufacture to the supply chain to meet the needs of 
existing  and  new  corporate  partners  and  extend  the  opportunities 
offered by our products into the fast growing India and Southern Asia 
markets. We anticipate further deals with manufacturing partners in 
other territories as we extend the reach of OptiBotix’s products around 
the world.  

The  company  has  now  signed  twenty  eight  agreements  since  the 
European  launch  of  it  products  at Vitafoods  in  May  2017,  and  USA 
product launch at Supply Side West in September 2017. These include 
ten agreements for the Probiotic division, six for SlimBiome®, and two 
for SweetBiotix®. Three of these agreements extend LPLDL® into drug 
biotherapeutics  with  one  agreement  for  SlimBiome®  as  a  Medical 
Device. In the LPLDL® drug biotherapeutics deals, the partner provides all 
funding for drug registration and approvals in return for exclusivity. With 
the  US  partner  deal,  OptiBiotix  receives  milestone  and/or  royalty 
payments based on product development and future product sales. This 
is  a  low  cost,  low  risk  approach  to  enter  the  pharmaceutical  space, 
which, if successful, has the potential to create significant value uplift 
for OptiBiotix in the years ahead. Similarly, for SlimBiome®, its registration 
as a medical device with CE mark extends the application of SlimBiome® 
from food products into high value medical products and opens up 
access  to  consumer  healthcare  and  pharmaceutical  markets  across 
Europe.  This  means  that  OptiBiotix’s  products  are  now  being 

commercialised  as 
ingredients,  medical  devices,  drug 
biotherapeutics, and supplements through retail and online platforms 
around the world. 

food 

This is all part of a commercial strategy based on closing out deals across 
multiple  levels  of  the  value  chain,  starting  with  manufacturing 
agreements (e.g Sacco, Knighton), royalty bearing license deals with 
formulation partners (e.g Nutrilinea, Cereal Ingredients) for the supply 
of  white  label  and  branded  products,  and  distribution  agreements 
directly  with  retailers.  This  allows  OptiBiotix  to  develop  multiple 
formulations and/or applications, which have the science, cost structure, 
and synergistic mode of action to create a wide product range, suitable 
for different territories in consumer health, pharmaceutical, and retail 
companies around the world.  

Of particular note in 2018 was the signing of two deals with global 
partners for SweetBiotix®, sweet natural healthy sugars which are not 
digested in the human gut and hence calorie free. These partners are 
looking to explore the potential to reduce the sugar content in a range 
of  applications,  in  particular  dairy.  These  agreements  are  part  of  a 
number  of  on-going  discussions  with  potential  partners  who  have 
expertise in either the manufacturing and/or application development 
of high value speciality ingredients within food and beverage products. 
One of these partners is funding the pilot scale up and supply of two 
batches of SweetBiotix® for consumer testing and further application 
development. Investors are cautioned that discussion with corporate 
partners takes place within a corporate process and timescale, and are 
often  subject  to  strict  confidentiality  clauses  which  prevents  any 
disclosure of progress or otherwise. 

With growing concerns over traditional sugars and artificial sweeteners 
there is the potential to replace existing ‘unhealthy’ sugars products with 
non-digestible, low calorie, healthy, SweetBiotix®. Publication of the 
results  on  our  human  studies  and  accompanying  media  reports  in 
national newspapers such as The Times has stimulated high industry 
interest and we anticipate further developments and announcements 
in this area in the future. 

The  focus  for  2019  is  on  further  extending  our  reach  into  new 
application areas and new territories, and translating industry interest 
into deal flow and further revenue growth. In addition to the registration 
of SlimBiome® as a medical device, and the development of LPLDL® as a 
pharmaceutical drug product, we will extend the application of LPLDL® 
from its use as a supplement into use as a food and dairy ingredient. 
This  is  in  line  with  our  strategy  of  building  revenues  and  market 
presence  of  our  patented  and  trademarked  products  (LPLDL®, 
SlimBiome®)  as  the  ‘Intel’  inside  a  wide  range  of  food,  beverage, 
supplement, and medical products around the world.  

The online platform launched in autumn 2018 creates another channel 
to market and a shop window for our technologies and products. The 

999

OptiBiotix Health Plc 

 
addition of CholBiome®, and CholBiome® 3X, and muesli pots to the 
store  has  lead  to  month  on  month  increase  in  sales.  We  anticipate 
adding new products, including SlimBiome® Medical, to the online store 
and growing contribution from online sales in 2019.  

Results 

OptiBiotix’s results for the 12 months ended 30 November 2018 are set 
out in the Consolidated Statement of Comprehensive Income.  

The results show revenue for the year of £514K. The majority of this 
income (£434k) was generated in the second half of the year (June to 
30 November 2018) as an increasing number of agreements started to 
generate revenues. These figures, albeit from a low base, represent a 
543% increase in income from H1 to H2 and a 169% increase on 2017 
income of £191K. As existing deals contribute to full year revenues, 
partners continue to grow sales with new product launches in 2019, 
and new agreements continue to be signed, we would hope to see 
continued revenue growth in 2019.  

Administrative  expenses  for  2018  were  £1,850,403,  down  £223,865 
(17.5%)  from  administrative  expenses  of  £2,074,268  in  2017.  This 
reflected a £141,719 reduction in research and development costs (2018: 
£160,673; 2017: £302,392) as the company transitions from a research 
and development business to a commercial business. Reductions were 
also  seen  in  patent  and  IP  costs  (2018:  £88,003;  2017:  £129,043)  as 
patents were granted reducing filing costs, and legal and professional 
fees ( 2018: £26,563; 2017: £130,729), which were higher in 2017 due to 
the public listing of SkinBiotherapeutics plc. Within 2018 administration 
expenses  of  £267,943  was  for  non-cash  expenses  representing 
depreciation, amortisation, and share based payment devaluations.  

The operating loss for the period was £1,498,896, which was £627,906 
less than for the same period last year (2017: £2,126,802).  

At 30 November 2018, the Company had £1.33 million cash in the bank. 
Once R&D tax credits, and recoverable VAT are added back, the balance 
was c. £1.67 million. On 14 December 2018, post accounting period, 
Probiotix Health Ltd, a wholly owned subsidiary of OptiBiotix Health, 
announced it had raised £1.025 million of capital through the issue of 
convertible  loan  notes  in  preparation  for  a  potential  initial  public 
offering.  Of  this  £198K  was  received  before  30  November  with  the 
remaining  received  post  accounting  period.  With  this  funding  and 
growing revenues, the cash position remains strong and sufficient to 
cover the delivery of existing commercial plans. 

The share of loss from OptiBiotix’s associate, SkinBiotherapeutics (SBTX), 
has increased substantially from £294,278 in 2017 to £448, 223 in 2018, 
representing an increase in SkinBiotherapeutics scientific and clinical 
activity. This is an accounting adjustment and has no impact on the 
Groups cash balance. 

Board and Management 

We  continue  to  evolve  the  Board  in  line  with  the  Company’s 
development. The  last  twelve  months  has  seen  a  number  of  board 
additions to reflect the increased commercial focus.  

We were pleased to announce the appointment of Neil Davidson CBE 
as  Non-Executive  Chairman  in  January  2018  and  Sean  Christie,  as  a 
Non-Executive Director, who joined us in September 2018. Neil brings 
to the Board over thirty years of operational and Board experience as 
Chairman and Chief Executive of FTSE 100, AIM, and private companies. 
Sean brings financial, investor and M&A expertise and a strong track 
record of delivering revenue growth and creating shareholder value. 
Both come with a wide network of contacts in the food industry and a 
wealth of experience on the Board of some of the UK’s largest public 
companies. Their addition to the board increases the Company’s sector 
specific  expertise  and  brings  experience  of  working  within  a  large 
publicly listed company.  

We believe with the addition of Neil and Sean, we have a well-balanced 
Board with scientific and commercial expertise in the founder and Chief 
Executive  Stephen  O’Hara  and  market  expertise  in  Non-Executive 
Director  Peter  Wennström,  one  of  the  world’s  leading  experts  in 
functional food innovation and marketing. Dr Sofia Kolyda as Director 
of Research and Development brings specialised expertise in prebiotics. 
They  are  complemented  by  Christina  Wood  who  brings  sales  and 
marketing expertise and our CFO Mark Collingbourne. 

Gareth Barker will step down from the board at the end of April 2019 
due to work commitments in his new role. Gareth was Vice President of 
Human Nutrition & Health (EMEA) at DSM and took on a new role of 
President of Personal Care and Aroma Ingredients at DSM in early 2018. 
On behalf of the Board, I would like to thank Gareth for his contribution 
in helping guide OptiBiotix through its early developmental years and 
wish him well in his new role at DSM. 

We anticipate further additions and changes to the management team 
and the Board as we extend the global reach of our products and in-line 
with the continued growth and expansion of the Company. 

At the end of the accounting period we announced that Dr Fred Narbel 
would join the board as Managing Director of the prebiotic division 
containing its SweetBiotix®, OptiBiotic® and microbiome modulating 
technology platforms. Frederic was Vice President of Sales for Nutrition 
Solutions at Agropur, a company with annualised sales of $6.4 billion 
(2017), and joined us on 1 March 2019. This appointment reflects the 
growing partner interest in OptiBiotix’s microbiome modulators and 
SweetBiotix®. Fred’s experience of speciality food ingredients will help 
drive the commercialisation of OptiBiotix’s pipeline of products, and in 
time,  add  another  revenue  stream  to  the  growing  revenues  from 
OptiBiotix’s LPLDL® and SlimBiome® products. 

Annual Report and Accounts 2018 10

Outlook 

The last twelve months have seen the continued transition of OptiBiotix 
from a research and development business to a company showing 
strong  commercial  traction  for  its  award  winning  products  and 
technologies, with significant deal flow and rapidly growing revenues. 

We  anticipate  further  revenue  growth  in  2019  as  existing  deals 
contribute to full year revenues, and partners continue to grow sales. 
More of our existing agreements will start to generate revenues in 2019, 
particularly with larger partners launching products in international 
markets  in  late  2019,  and  new  agreements  continue  to  be  signed 
in 2019.  

We  anticipate  further  revenue  growth  will  occur  from  our  online 
platform (OPTIBIOTIX.Online), which has been making good progress 
under the leadership of Steve Riley. Sales have increased month on 
month as we have extended our range with the launch of new products 
(e.g.  Muesli,  CholBiome®),  and  invested  in  a  mixture  of  digital  and 
newspaper advertising. To support online sales growth we anticipate 
adding new products, including SlimBiome® Medical, to the online store 
and extending the GoFigure® product range. We anticipate revenues in 
2019 from SlimBiome® Medical (which received its CE mark and medical 
device  registration  at  the  end  of  the  accounting  period),  and  our 
SweetBiotix®,  OptiBiotic®  and  microbiome  modulating  platforms. 
Revenue growth from these areas will benefit from the appointment of 
Frederic Narbel as Managing Director of OptiBiotix’s prebiotic division. 

We are seeing growing interest from international partners in OptiBiotix’s 
own label CholBiome® and GoFigure® brands and intend to invest in 
marketing to build the brand. If this is successful we believe there are 
opportunities to leverage the brand to launch OptiBiotix own label 
products with partners across the world and build substantive value in 
these assets. This is being supported by a large investment in patents 
and  trademarks  to  broaden  protection  in  international  markets. 
OptiBiotix  now  has  an  extensive  and  valuable  intellectual  property 
portfolio of over ninety patents and forty trademarks.  

The Company will continue to invest in its science and clinical studies 
and  present  these  in  peer  reviewed  scientific  journals  and  at 
international conferences, with the endorsement of world key opinion 
leaders. These presentations and publications raise OptiBiotix’s profile 
and reputation, attract commercial and media interest in our products, 
and provide the scientific evidence for sales and marketing literature in 
support of product commercialisation. We are particularly pleased that 
our science continues to win awards at scientific conferences as this 
increases industry interest. We were particularly pleased to win the best 
scientific  abstract  at  ProBiota  2018  with  DSM  for  the  first  reported 
publication of an optimised prebiotic for LGG®, contained within DSM’s 
Culturelle® range. We see the development of species or genera specific 
prebiotics  which  can  selectively  enhance  the  growth  and  health 
benefits of existing probiotic products as a growing area of interest to 

11

OptiBiotix Health Plc 

the  probiotic  industry,  a  market  expected  to  be  worth  more  than 
$46.5 billion by 2020 (Markets and Markets). 

As we extend our reach into new application areas and new territories, 
the scale of the opportunity enlarges. The US is one of the largest and 
fastest growing probiotic markets in the world and an area of significant 
potential  growth  in  2019.  With  supplements  alone  accounting  for 
US$2.06 billion sales and projected to grow by 55% to US$3.3 billion by 
2021, and food and beverage products accounting for $5 billion per 
annum,  (“Trends,  Innovations  and  Opportunities  Driving  The  Global 
Probiotics Market, Euromonitor International June 2017”), the US is a large 
and rapidly growing market opportunity for probiotics such as LPLDL®. 
We were pleased to announce post year end, in February 2019, that the 
Independent Expert Panel ruled in favour of LPLDL® GRAS status. This is a 
significant achievement and a major commercial milestone for the US 
market as it expands the potential applications of LPLDL® from use as a 
supplement to inclusion as a functional ingredient in a wide range of 
food, dairy, beverage, and high value medical food applications, across 
the USA. The regulatory approval and extension of our products into 
other  application  areas,  particularly  food  and  beverages,  reflects  a 
growing confidence in our products and the scale of the opportunity. 
We would hope to see the expansion of territories and application areas 
leading to announcements of deals with a number of national and 
international partners in the future. 

With  a  population  of  1.3  billion  people  and  cardiovascular  disease 
accounting for up to 26% of all deaths (The Times of India June 8, 2014), 
15-20% of children overweight, and 60-70% of adolescents remaining 
overweight  or  obese  in  their  adulthood  years  India  represents  a 
substantial opportunity for OptiBiotix’s products. In a recent visit to India 
the  Company  met  with  around  thirty  companies  who  identified  a 
growing trend within India to improve Health and Wellbeing and an 
interest in products to help manage lifestyle diseases like heart disease 
and obesity. We believe India offers a substantial business opportunity 
which if realised could deliver multimillion pound revenues annually.  

OptiBiotix’s  technology  platforms  are  being  developed  into  self-
sustaining business units with a commercial focus lead by directors who 
have  the  business  development,  sales  skills  and  experience  to  fully 
exploit the revenue potential of the products. As these develop, our aim 
is to separate them into wholly owned separate legal entities with the 
potential for an independent exit by a trade sale, or listing separately or 
collectively in UK, Europe, or the US, depending on market conditions. 
This allows OptiBiotix shareholders to benefit from the appreciation of 
this asset plus any dividends which may be returned in recognition of 
this value uplift. This is consistent with our strategy of providing investors 
a broad based investment portfolio across a number of areas in the 
microbiome space which diversifies risk, whilst offering shareholders 
multiple opportunities in this exciting space. 

The  transition  from  a  technology  to  product  company  requires  a 
different focus and skill set. The appointment of Neil Davidson and Sean 
Christie is the start of the process of bringing board level sector and 

 
into agreements in new territories and application areas in the months 
ahead to continue rapidly growing revenues in this new and exciting 
area of science which has the potential to revolutionise the future of 
healthcare.  

On behalf of everyone at OptiBiotix Health we would like to thank our 
investors for their continued support and look forward to an exciting 
future.  

N Davidson and S OHara 
26 April 2019 

FTSE100 expertise into the company. We are pleased that both Neil and 
Sean have invested in the region of £450,000 in OptiBiotix since their 
appointment early in 2018. This level of financial commitment from such 
established  industry  leaders  as  new  board  members  provides 
reassurance to the Board on its strategy. 

The  Company  is  developing  technology  and  products  in  the 
microbiome space, a market growing at 22.3% per year, and described 
by health experts as “healthcare’s most promising and lucrative frontier” 
(Markets and Markets). The Board believes OptiBiotix® is at the leading 
edge in this space and has the right strategy, team, and award winning 
technology and products in place, to build a substantive business over 
the next few years. We are particularly pleased by the results customers 
are  achieving  with  our  products  with  substantive  reductions  in 
cholesterol using CholBiome® X3 and typical weight loss of 2-3lbs per 
week with SlimBiome® and GoFigure® products.  

The  last  twelve  months  has  seen  continued  progress  in  building  a 
broad-based microbiome business with a diversity of IP and commercial 
agreements which provides shareholders with multiple opportunities. 
The  large  number  of  agreements  signed  in  2018  across  multiple 
application areas and territories represent early tangible evidence of this 
progress. The next stage of the process is to build on existing revenues 
streams to continue building sales in 2019 against a continued low-cost 
base creating profitable divisions across all areas of the Company. 

We are pleased that our strategy of developing microbiome products 
with a strong scientific and clinical evidence base with key opinion 
leader support has provided clear product differentiation and stimulated 
high commercial interest. We look forward to converting this interest 

Annual Report and Accounts 2018 12

Strategic Report 

Review Of Business 

Financial And Capital Risk Management 

The Directors constantly monitor the financial risks and uncertainties 
facing the Group with particular reference to the exposure of credit risk 
and liquidity risk. They are confident that suitable policies are in place 
and that all material financial risks have been considered. The financial 
risk management objectives and policies can be found within note 23 
of the financial statements. 

The Board’s objective is to maintain a balance sheet that is both efficient 
and delivers long term shareholder value. The Group had cash balances 
of  £1,324,307  as  at  30  November  2018  and  had  no  short-term 
borrowings. The Board continues to monitor the balance sheet to ensure 
it has an adequate capital structure. 

A review of the business of the Group, 
together  with  comments  on  future 
developments is given in the Chairman’s 
and  Chief  Executive’s  Statement  on 
pages 2 to 12. 

Principal Risks And 
Uncertainties Facing 
The Group 

Technology and products 
The Group is involved in microbiome modulation products discovery 
and  development.  The  development  and  commercialisation  of  its 
intellectual property and future products will require human nutritional 
studies and there is a risk that products may not perform as expected. 
This  risk  is  common  to  all  new  products  developed  for  human 
consumption. 

Technologies used within the food, beverage and healthcare market 
place are constantly evolving and improving. There is a risk that the 
Group’s  products  may  become  outdated  or  their  commercial  value 
decrease as improvements in technology are made and competitors 
launch competing products. To mitigate this risk the Group is working 
with industry key opinion leaders, will attend international conferences 
and intends to develop a research and development department which 
will keep up with the latest developments in the industry. 

Intellectual Property 
The Group is focused on protecting its IP and seeking to avoid infringing 
on third parties’ IP. To protect its products, the Group is building and 
securing patents to protect its key products. However, there remains the 
risk that the Group may face opposition from third parties to patents 
that  it  seeks  to  have  granted  and  that  the  outstanding  patent 
applications  are  not  granted.  The  Group  engages  legal  advisers  to 
mitigate the risk of patent infringement and to assist with the protection 
of the Group’s IP. 

13

OptiBiotix Health Plc 

 
Principal Risks And Uncertainties 

Market Risks

Impact

Mitigation 

Brexit 

New regulations could add complexity and delays 
to operations. 

The  current  consensus  is  that  Brexit  will  not  affect  the 
regulations that are relevant to our business. 

Currency  fluctuations  could  increase  costs  and 
affect profitability. 

Currency fluctuations will impact both sales and costs. Our 
initial product offering is not price-sensitive. Substantial cost 
increases will be passed on.

Technology 

The Group’s platform is currently unique. Rapid 
technological  advances  could  see  competitor 
products being launched.

The  Group  has  product  development  plans  in  place  for 
improved technology as well as for a wider product portfolio 
that includes additional innovative solutions for the targeted 
consumer groups.

Operational Risks

Impact

Mitigation 

Technology 

Commercialisation 

The  Group  is  launching  products  that  are  not 
already available in the consumer market.

The Group has responded to consumer demand.

The  Group  is  making  the  transition  from  a 
research-based organisation to a full commercial 
organisation. Manufacturing set-up and learning 
curve could delay sales or could impact our rate 
of growth.

The  Group  recruited  experienced  management  and 
consultants to manage the process and negotiate contracts.

Financial Risks

Impact

Mitigation 

Future funding  
requirements 

Legal Risks

Intellectual  
Property  
litigation 

Our current funding covers current requirements. 
Potential as yet unidentified opportunities may 
not be pursued with the existing funding.

Management  will  analyse  major  opportunities 
and  present  them  in  additional  business  cases 
when warranted.

Impact

Mitigation 

Any claim brought against us would detract the 
Company from its business. 

The Group engages with IP specialists to ensure 
we have a strong position. To our knowledge we 
do not infringe on any patents.

Annual Report and Accounts 2018 14

 
 
 
 
 
 
 
 
 
 
 
Key Performance Indicators 

Non-financial 

Financial

Year to 
30 November
2018
£’000

Year to  
30 November  
2017 
£’000 

Revenue
Profit/(Loss) for the period
Cash as at 30 November 2018

514
(1,893)
1,324

191 
1,918 
1,247 

During the year to 30 November 2018 the company has achieved a 
number of key objectives which continue to build shareholder value. 
These include: 

•         Eighteen commercial agreements with manufacturing, application 

The Board recognises the importance of KPIs in driving appropriate 
behaviour  and  enabling  of  Group  performance.  For  the  year  to 
30  November  2018  the  primary  KPI’s  were  the  completion  of 
commercial agreements and the expansion of the Optibiotic® platform. 
The Group intends to review the following non-financial KPIs going 
forward: 

1. Customer relationships 

2.

IP and trademark registrations 

3. Service quality and brand awareness 

4. Attraction, motivation and retention of employees 

Dividends 

and distribution partners 

No dividends can be distributed for the year ended 30 November 2018. 

•         Award for SlimBiome® for Weight Management Ingredient of the 
Year at Vitafoods 2018 and ‘Best Functional Ingredient for Health 
and Wellbeing’ at Food Matters 

•         Award  for  best  scientific  abstract  at  ProBiota  2018  for  the 
identification and development of a prebiotic which selectively 
enhances the growth of Lactobacillus rhamnosus GG (“LGG®”) 

•         The  granting  of  medical  device  status  and  a  CE  mark  for 

SlimBiome® 

•         The appointment of Neil Davidson as Non-executive Chairman 
bringing sector and FTSE 100 experience to the company. 

Future Developments 

The Chairman’s and Chief Executive Statement on pages 2-12 gives 
information on the future outlook of the Group. 

On Behalf Of The Board 

S P O’Hara 
26 April 2019

15

OptiBiotix Health Plc 

 
Directors’ Report 

The  Directors  present  their  report  and  the  audited  financial 
statements of the Group for the year to 30 November 2018. 

Principal Activity 
The  principal  activity  of  the  Group  is  that  of  research  and 
development into microbiome modulators. 

Directors 
The Directors who served the company during the year and up to 
the date of this report were as follows: 

Executive Directors 
S P O’Hara  
C Wood  
P Rehne  
S Kolyda (Appointed on 4 July 2018) 
F Narbel (Appointed on 1 March 2019) 

Non-executive Directors 
G Barker  
P Wennström  
R Davidson (Appointed on 1 January 2018) 
M Christie (Appointed on 10 September 2018) 

Directors’ Remuneration 
The Directors are entitled to receive relevant fees, as detailed in the 
Directors’ remuneration in Note 4. 

Directors and their interests 
The Directors of the Group held the following beneficial interests in 
the shares and share options of OptiBiotix at the date of this report: 

Issued Share Capital

Share Warrants

Share Options 

Ordinary
shares of
£0.02 each

10,103,031
478,000
–
125,000
357,722
–
–
–
–

Percentage
Held 

Ordinary
shares of 
£0.02 each

Warrant
exercise
price

Ordinary
shares of 
£0.02 each

11.8%
0.56%
–
0.14%
0.42%
–
–
–
–

–

–

–
–
–
–
–

–

–

–
–
–
–
–

6,099,135
385,000
–
100,000
–
500,000
500,000
165,000
358,722

Option 
exercise 
price 

£0.08 
£0.73 
– 
£0.95 
– 
£0.695 
£0.785 
£0.73 
£0.20 

S P O’Hara
R Davidson
P Wennström 
M Christie
G Barker 
C Wood
F Narbel 
S Kolyda
S Kolyda

The share options held by S P O’Hara were granted on 17 September 2016 and are exercisable at £0.08 at any time up 16 September 2024, subject 
to vesting conditions. 

The share options held by R Davidson were granted on 13 July 2018 and are exercisable at £0..73 at any time up 13 July 2024, subject to vesting 
conditions. 

The share options held by M Christie were granted on 21 September 2018 and are exercisable at £0.95 at any time up 21 September 2028, subject 
to vesting conditions. 

The share options held by F Narbel were granted on 27 March 2019 and are exercisable at £0.785 at any time up 27 March 2029, subject to vesting 
conditions. 

The 358,772 share options held by S Kolyda were granted on 10 March 2015 and are exercisable at £0.20 at any time up 10 March 2025, subject to 
vesting conditions. 

The 165,000 share options held by S Kolyda were granted on 13 September 2018 and are exercisable at £0.73 at any time up 13 September 2019, 
subject to vesting conditions. 

The share options held by C Wood were granted on 29 June 2017 and are exercisable at £0.695 at any time up to 29 June 2027, subject to vesting 
conditions.

Annual Report and Accounts 2018 16

Substantial Shareholdings 

Statement Of Directors’ Responsibilities 

Substantial shareholdings including Directors as at 23 April 2019 were 
as follows: 

The Directors are responsible for preparing the Directors’ Report and the 
financial statements in accordance with applicable laws and regulations. 

Stephen O’Hara
Finance Yorkshire Seedcorn LP

% of shares issued 
11.18 
11.05 

The share price per share at 30/11/2018 was £0.92 (30/11/2017: 
£0.69) 

Financial Instruments 

The Group’s exposure to financial risk is set out in Note 23 to the financial 
statements. 

Company law requires the Directors to prepare financial statements for 
each financial period. Under that law the Directors have, as required by 
the AIM Rules for Companies of the London Stock Exchange, elected to 
prepare financial statements in accordance with International Financial 
Reporting Standards (IFRS) as adopted for use in the European Union. 
Under  company  law  the  Directors  must  not  approve  the  financial 
statements unless they are satisfied that they give a true and fair view 
of the state of affairs of the Company and of the profit or loss of the 
Company for that period. In preparing these financial statements, the 
Directors are required to: 

•      select  suitable  accounting  policies  and  then  apply  them 

Research And Development 

consistently; 

The  Chairman’s  and  Chief  Executive  Statement  on  page  2-12  gives 
information on the Group’s research and development activities. 

Political And Charitable Contributions 

The Group made no charitable or political contributions during the 
period. 

Events After The Reporting Period 

Refer to Note 24 to the financial statements for further details. 

Publication Of Accounts On Group 
Website 

Financial  statements  are  published  on  the  Group’s  website.  The 
maintenance and integrity of the website is the responsibility of the 
Directors. The  Directors’  responsibilities  also  extend  to  the  financial 
statements contained therein. 

Going Concern 

The financial statements have been prepared on the assumption that 
the Group is a going concern. When assessing the foreseeable future, 
the Directors have looked at the budget for the next 12 months from 
the  date  of  this  report,  the  cash  at  bank  available  as  at  the  date  of 
approval of this report and are satisfied that the Group should be able 
to cover its quoted maintenance cost, other administrative expenses, as 
well as its ongoing research and development expenditure. 

After making enquiries, the Directors have a reasonable expectation that 
the Group has adequate resources to continue in operational existence 
for the foreseeable future. Accordingly, they continue to adopt a going 
concern basis in preparing the annual report and financial statements. 

17

OptiBiotix Health Plc 

•      make judgements and estimates that are reasonable and prudent; 

•      state  whether  the  company  financial  statements  have  been 
prepared  in  accordance  with  IFRS  as  adopted  by  the  European 
Union, subject to any material departures disclosed and explained 
in the financial statements; and 

•      prepare the financial statements on the going concern basis, unless 
it is inappropriate to presume that the company will continue in 
business. 

The Directors confirm that the financial statements comply with the 
above requirements. 

The Directors are responsible for keeping adequate accounting records 
that are sufficient to show and explain the company’s transactions and 
disclose with reasonable accuracy at any time the financial position of 
the company and enable them to ensure that the financial statements 
comply with the Companies Act 2006. They are also responsible for 
safeguarding  the  assets  of  the  company  and  hence  for  taking 
reasonable steps for the prevention and detection of fraud and other 
irregularities. 

Statement As To Disclosure Of 
Information To Auditors 

So far as the Directors are aware, there is no relevant audit information 
(as defined by Section 418 of the Companies Act 2006) of which the 
Company’s auditor is unaware, and each Director has taken all the steps 
that he ought to have taken as a Director in order to make himself aware 
of  any  relevant  audit  information  and  to  establish  that  the  Group’s 
auditor is aware of the information.

 
Auditor 

Jeffreys Henry LLP will be proposed for re-appointment as auditors at 
the forthcoming Annual General Meeting. 

Strategic Report 

In accordance with section 414C(11) of the Companies Act 2006 the 
Group chooses to report the review of the business, the future outlook 
and  the  risks  and  uncertainties  faced  by  the  Group  in  the  Strategic 
Report on page 13. 

On Behalf Of The Board 

S P O’Hara 
26 April 2019

Annual Report and Accounts 2018 18

 
Independent Auditor’s Report to the Members of 
OptiBiotix Health Plc 

Opinion 

We have audited the financial statements of OptiBiotix Health Plc (the 
‘parent company’) and its subsidiaries (the ‘Group’) for the year ended 
30  November  2018  which  comprise  the  consolidated  income 
statement,  consolidated  statement  of  comprehensive 
income, 
consolidated statement of changes in equity, company statement of 
changes  in  equity,  consolidated  statement  of  financial  position, 
company statement of financial position, consolidated statement of 
cash flows, company statement of cash flows and notes to the financial 
statements, including a summary of significant accounting policies. The 
financial reporting framework that has been applied in the preparation 
of the Group financial statements is applicable law and International 
Financial  Reporting  Standards  (IFRSs)  as  adopted  by  the  European 
Union. The financial reporting framework that has been applied in the 
preparation of the parent company financial statements is applicable 
law and International Financial Reporting Standards (IFRSs) as adopted 
by the European Union as applied in accordance with the provision of 
the Companies Act 2006. 

In our opinion: 

•      the financial statements give a true and fair view of the state of the 
Group’s and of the parent company’s affairs as at 30 November 2018 
and of the Group’s loss for the year then ended; 

•      the Group financial statements have been properly prepared in 

accordance with IFRSs as adopted by the European Union; 

•      the  parent  company  financial  statements  have  been  properly 
prepared in accordance with IFRS’s as adopted by the European 
Union  as  applied  in  accordance  with  the  provisions  of  the 
Companies Act 2006; and 

•      the financial statements have been prepared in accordance with the 

requirements of the Companies Act 2006. 

Basis for opinion 

We conducted our audit in accordance with International Standards on 
Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under 
those standards are further described in the Auditor’s responsibilities for 
the  audit  of  the  financial  statements  section  of  our  report.  We  are 
independent  of  the  company  in  accordance  with  the  ethical 
requirements that are relevant to our audit of the financial statements 
in  the  UK,  including  the  FRC’s  Ethical  Standard  as  applied  to  listed 
entities,  and  we  have  fulfilled  our  other  ethical  responsibilities  in 
accordance with these requirements. We believe that the audit evidence 
we have obtained is sufficient and appropriate to provide a basis for our 
opinion. 

Conclusions relating to going concern 

We have nothing to report in respect of the following matters in relation 
to which the ISAs (UK) require us to report to you where: 

•      the Directors’ use of the going concern basis of accounting in the 
preparation of the financial statements is not appropriate; or 

•      the Directors have not disclosed in the financial statements any 
identified material uncertainties that may cast significant doubt 
about the Group’s or the parent company’s ability to continue to 
adopt the going concern basis of accounting for a period of at least 
twelve months from the date when the financial statements are 
authorised for issue. 

Our audit approach 

Overview 

Key Audit Matters 

Key audit matters are those matters that, in our professional judgment, 
were of most significance in our audit of the financial statements of the 
current period and include the most significant assessed risks of material 
misstatement (whether or not due to fraud) we identified, including 
those which had the greatest effect on: the overall audit strategy, the 
allocation of resources in the audit; and directing the efforts of the 
engagement team. These matters were addressed in the context of our 
audit of the financial statements as a whole, and in forming our opinion 
thereon, and we do not provide a separate opinion on these matters. 
This is not a complete list of all risks identified by our audit. 

•      Carrying value of investments and recoverability of receivables 

•      Capitalisation of development costs and carrying value of intangible 

assets 

These are explained in more detail below 

Audit scope 

•      We  conducted  audits  of  the  complete  financial  information  of 
OptiBiotix Health Plc, OptiBiotix Limited, The Healthy Weight Loss 
Company Limited and ProBiotix Health Limited. 

•      We performed specified procedures over certain account balances 

and transaction classes at other Group companies. 

•      Taken together, the Group companies over which we performed 
our audit procedures accounted for 100% of the absolute profit 
before tax (i.e. the sum of the numerical values without regard to 
whether they were profits or losses for the relevant reporting units) 
and 100% of revenue. 

19

OptiBiotix Health Plc 

 
Key audit matter

How our audit addressed the key audit matter

Carrying value of  investments and recoverability of Group 
receivables – Company Risk 

The amount owed to the Company at the year- end by the subsidiary 
OptiBiotix Limited is £4,044,646. 

The carrying value of investments in Group companies are as follows: 

OptiBiotix Limited : £2,000,000 

ProBiotix Health Limited : £1,000 

The Healthy Weight Loss Company Limited : £50,000 

Impairment of The Healthy Weight Loss Company Limited:  

As the company has not been trading as of September 2018, the 
Directors feel it is prudent to write down the investment to £50,000 
to reflect change in trading status. The remaining investment reflects 
the value of the ‘gofigure’ brand held.  

Carrying value of investments – Group Risk 

At the year end the Group had investments of £3.74 million made up 
of the investment in SkinBiotherapeutics plc. 

We carried out a review of the investments held in the subsidiaries. 

Management’s 
underlying assumptions audited. 

impairment  workings  were  reviewed  and  the 

We reviewed management’s basis for impairment across the Company 
and agree with their approach. 

As part of the review of management’s forecasts, consideration was 
given to the capability of the subsidiary to repay the amount within a 
12-month period.  

The estimation of the residual value held in The Healthy Weight Loss 
Company Limited has been assessed. 

investment 

We  reviewed  the 
in  SkinBiotherapeutics  plc  for 
impairment, with particular consideration given to the fact that the 
market value of OptiBiotix Health Plc’s holding at the year-end was 
greater than the carrying value of the investment.

The  Directors  have  assessed  whether 
in 
SkinBiotherapeutics plc requires impairment and have concluded that 
it does not, by reference to the company’s share price.

investment 

the 

Carrying  value  of  intangible  assets  and  capitalisation  of 
development costs 

The Group had intangible assets of £2.25 million at the year ended 
31 December 2018 (2017: £1.92 million), of which £467,639 (2017: £Nil) 
were development costs capitalised in the year. 

The  remaining  costs  are  comprised  of  the  fair  value  of  patents 
acquired on the acquisition of OptiBiotix Limited. 

The  Directors  have  assessed  whether  intangible  assets  require 
impairment and have concluded that they do not. The patents are 
amortised in a straight line over 20 years, the period in which the 
Directors believe the assets will generate revenue. 

The development costs are amortised in a straight line over 10 years, 
a period the Directors believe to be in line with industry standard. 

Intangible assets in the accounts have been allocated useful lives and 
therefore  an  annual  impairment  test  is  not  required.  However,  as 
OptiBiotix Limited is loss making we considered if there were indicators 
of impairment and reviewed the discounted cash flow forecasts. 

The development costs capitalised in the year were evaluated against 
the recognition criteria of IAS38. The estimated useful economic life 
assigned to the costs was reviewed.

Annual Report and Accounts 2018 20

 
 
 
Our Application Of Materiality 

The scope of our audit was influenced by our application of materiality. We set certain quantitative thresholds for materiality. These, together with 
qualitative considerations, helped us to determine the scope of our audit and the nature, timing and extent of our audit procedures on the individual 
financial statement line items and disclosures and in evaluating the effect of misstatements, both individually and in aggregate on the financial 
statements as a whole. 

Based on our professional judgment, we determined materiality for the financial statements as a whole as follows:

Group financial statements

Company financial statements

Overall materiality 

£126,000 (2017: £94,000).

£120,000 (2017: £52,000).

How we determined it

1.5% of gross assets. 

1% of gross assets. 

(2017:  average  of  3%  revenue,  10%  profit/loss 
before tax, 1% gross assets).

(2017:  average  of  3%  revenue,  10%  profit/loss 
before tax, 1% gross assets).

Rationale for  
benchmark applied 

We believe that gross assets is a primary measure 
used  by 
the 
performance of the Group, whilst the subsidiaries 
are in varied states of development and trading.

in  assessing 

shareholders 

shareholders 

We believe that gross assets is a primary measure 
used  by 
the 
performance  of  the  Company,  given  that  it  is 
largely  a  holding  company  for  the  trading 
subsidiaries.

in  assessing 

How we tailored the audit scope 
We tailored the scope of our audit to ensure that we performed enough 
work to be able to give an opinion on the financial statements as a 
whole, taking into account the structure of the Group and the Company, 
the accounting processes and controls, and the industry in which they 
operate. 

The Group financial statements are a consolidation of 4 reporting units, 
comprising the Group’s operating businesses and holding companies. 

We performed audits of the complete financial information of OptiBiotix 
Health plc, OptiBiotix Limited and The Healthy Weight Loss Company 
Limited reporting units, which were individually financially significant 
and accounted for 100% of the Group’s revenue and 100% of the Group’s 
absolute profit before tax (i.e. the sum of the numerical values without 
regard to whether they were profits or losses for the relevant reporting 
units). The Group engagement team performed all audit procedures. 

For each component in the scope of our Group audit, we allocated a 
materiality that is less than our overall Group materiality. The range of 
materiality allocated across components was between £41,000 and 
£52,000. 

We agreed with the Audit Committee that we would report to them 
misstatements identified during our audit above £6,300 for the Group 
(2017: £4,700) and £6,000 for the Parent as well as misstatements below 
those amounts that, in our view, warranted reporting for qualitative 
reasons. 

An overview of the scope of our audit 

As part of designing our audit, we determined materiality and assessed 
the  risks  of  material  misstatement  in  the  financial  statements.  In 
particular, we looked at where the Directors made subjective judgments, 
for example in respect of significant accounting estimates that involved 
making assumptions and considering future events that are inherently 
uncertain.  As  in  all  of  our  audits  we  also  addressed  the  risk  of 
management override of internal controls, including evaluating whether 
there was evidence of bias by the Directors that represented a risk of 
material misstatement due to fraud. 

21

OptiBiotix Health Plc 

 
Other information 

The  Directors  are  responsible  for  the  other  information.  The  other 
information comprises the information included in the annual report, 
other than the financial statements and our auditor’s report thereon. 
Our  opinion  on  the  financial  statements  does  not  cover  the  other 
information and, except to the extent otherwise explicitly stated in our 
report, we do not express any form of assurance conclusion thereon. 

In  connection  with  our  audit  of  the  financial  statements,  our 
responsibility is to read the other information and, in doing so, consider 
whether  the  other  information  is  materially  inconsistent  with  the 
financial  statements  or  our  knowledge  obtained  in  the  audit  or 
otherwise appears to be materially misstated. If we identify such material 
inconsistencies or apparent material misstatements, we are required to 
determine whether there is a material misstatement in the financial 
statements or a material misstatement of the other information. If, based 
on the work we have performed, we conclude that there is a material 
misstatement of this other information, we are required to report that 
fact. We have nothing to report in this regard. 

Opinions on other matters prescribed by 
the Companies Act 2006 

In our opinion, based on the work undertaken in the course of the audit: 

•     the information given in the strategic report and the Directors’ report 
for the financial year for which the financial statements are prepared 
is consistent with the financial statements; and 

•     the strategic report and the Directors’ report have been prepared in 

accordance with applicable legal requirements. 

Matters on which we are required to 
report by exception 

•     certain disclosures of Directors’ remuneration specified by law are 

not made; or 

•     we  have  not  received  all  the  information  and  explanations  we 

require for our audit. 

Responsibilities of Directors 

As explained more fully in the Directors’ responsibilities statement set 
out on pages 16-17, the Directors are responsible for the preparation of 
the financial statements and for being satisfied that they give a true and 
fair view, and for such internal control as the Directors determine is 
necessary to enable the preparation of financial statements that are free 
from material misstatement, whether due to fraud or error. 

In preparing the financial statements, the Directors are responsible for 
assessing the Group’s and parent company’s ability to continue as a 
going  concern,  disclosing,  as  applicable,  matters  related  to  going 
concern and using the going concern basis of accounting unless the 
Directors either intend to liquidate the group or the parent company or 
to cease operations, or have no realistic alternative but to do so. 

Auditor’s responsibilities for the audit of 
the financial statements 

Our objectives are to obtain reasonable assurance about whether the 
financial statements as a whole are free from material misstatement, 
whether  due  to  fraud  or  error,  and  to  issue  an  auditor’s  report  that 
includes our opinion. Reasonable assurance is a high level of assurance, 
but is not a guarantee that an audit conducted in accordance with ISAs 
(UK)  will  always  detect  a  material  misstatement  when  it  exists. 
Misstatements can arise from fraud or error and are considered material 
if, individually or in the aggregate, they could reasonably be expected 
to influence the economic decisions of users taken on the basis of these 
financial statements. 

In the light of the knowledge and understanding of the Group and 
parent company and its environment obtained in the course of the 
audit, we have not identified material misstatements in the strategic 
report or the Directors’ report. 

A further description of our responsibilities for the audit of the financial 
statements is located on the Financial Reporting Council’s website at: 
www.frc.org.uk/auditorsresponsibilities. This description forms part of 
our auditor’s report. 

We have nothing to report in respect of the following matters in relation 
to which the Companies Act 2006 requires us to report to you if, in our 
opinion: 

Other matters which we are required to 
address 

•     adequate accounting records have not been kept by the parent 
company, or returns adequate for our audit have not been received 
from branches not visited by us; or 

•     the  parent  company  financial  statements  [and  the  part  of  the 
Directors’ remuneration report to be audited] are not in agreement 
with the accounting records and returns; or 

We were appointed as auditors by the company at the Annual General 
Meeting on 11 June 2018 to audit the financial statements for the period 
ending  30  November  2018.  Our  total  uninterrupted  period  of 
engagement is 5 years, covering the periods ending 30 November 2014 
to 30 November 2018. 

Annual Report and Accounts 2018 22

The non-audit services prohibited by the FRC’s Ethical Standard were 
not  provided  to  the  Group  or  the  parent  company  and  we  remain 
independent of the Group and the parent company in conducting our 
audit. 

In addition to the audit, the firm provides tax compliance services to 
OptiBiotix Health Plc and its subsidiaries. 

Our audit opinion is consistent with the additional report to the audit 
committee. 

Use of this report 

This report is made solely to the company’s members, as a body, in 
accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our 
audit  work  has  been  undertaken  so  that  we  might  state  to  the 
company’s members those matters we are required to state to them in 
an  auditor’s  report  and  for  no  other  purpose.  To  the  fullest  extent 
permitted by law, we do not accept or assume responsibility to anyone 
other than the company and the company’s members as a body, for our 
audit work, for this report, or for the opinions we have formed. 

Sudhir Rawal 
(Senior Statutory Auditor) 

For and on behalf of  

Jeffreys Henry LLP, Statutory Auditor 
Finsgate 
5-7 Cranwood Street 
London  
EC1V 9EE 

26 April 2019 

23

OptiBiotix Health Plc 

 
 
Consolidated Statement of Comprehensive Income 

Revenue
Cost of sales

Gross Profit

Share based payments
Depreciation and amortisation
Other administrative costs

Total administrative costs

Operating (loss)
Finance cost
Finance income

Share of loss from associate
Profit on disposal of subsidiary

Profit/(loss) before Income tax
Income tax

Profit/(loss) for the period
Other comprehensive income

Total comprehensive income for the period

Total comprehensive income attributable to: 
Owners of the company
Non-controlling interests

Earnings per share from continued operations 
Basic profit/(loss) per share – pence
Diluted profit/(loss) per share – pence

The notes on pages 33 to 53 form part of these financial statements

Notes

Year ended 
30 November 2018
£

Year ended  
30 November 2017 
£ 

514,289
(162,782)

351,507

128,222
141,908
1,580,273

(1,850,403)

(1,498,896)
–
169

169
(448,223)
–

(1,946,950)
54,371

(1,892,579)
–

(1,892,579)

(1,919,276)
26,697

(1,892,579)

(2.33)p
(2.33)p

191,073 
(73,706) 

117,367 

56,932 
119,966 
2,067,271 

(2,244,169) 

(2,126,802) 
(6,154) 
142 

(6,012) 
(294,278) 
4,116,286 

1,689,194 
228,447 

1,917,641 
– 

1,917,641 

1,907,441 
10,200 

1,917,641 

2.43p 
2.17p 

6

5
5

12

7

8

Annual Report and Accounts 2018 24

Consolidated Statement of Financial Position 

ASSETS 
Non-current assets 
Intangibles
Property, plant & equipment
Investments

CURRENT ASSETS 
Inventories
Trade and other receivables
Current tax asset
Cash and cash equivalents

TOTAL ASSETS

EQUITY 
Shareholders’ Equity 
Called up share capital
Share premium
Share based payment reserve
Merger relief reserve
Retained Earnings
Non-controlling interest

Total Equity

LIABILITIES 
Current liabilities 
Trade and other payables

Non – current liabilities 
Deferred tax liability

TOTAL LIABILITIES

TOTAL EQUITY AND LIABILITIES

Notes

As at
30 November 2018
£

As at 
30 November 2017 
£ 

10
11
12

13
14
7
15

16

18

19

2,253,089
3,143
3,740,799

5,997,031

30,433
373,803
303,952
1,324,307

2,032,495

8,029,526

1,694,488
1,603,904
602,739
1,500,000
1,624,348
36,897

7,062,376

520,989

520,989

446,161

446,161

967,150

1,927,226 
6,561 
4,189,022 

6,122,809 

8,890 
106,122 
183,951 
1,247,431 

1,546,394 

7,669,203 

1,586,628 
6,279,718 
474,517 
1,500,000 
(2,805,347) 
10,200 

7,045,716 

239,395 

239,395 

384,092 

384,092 

623,487 

8,029,526

7,669,203 

These financial statements were approved and authorised for issue by the Board of Directors on 26 April 2019 and were signed on 
its behalf by: 

S P O’Hara 
Director 
Company Registration no. 05880755  
The notes on pages 33 to 53 form part of these financial statements 

25

OptiBiotix Health Plc 

 
Consolidated Statement of Changes in Equity 

Called up
Share capital
£

Retained
Earnings
£

Non-
Share Controlling
interest
£

Premium
£

Merger
Relief
Reserve
£

Share-
based
Payment
reserve
£

Total 
equity 
£ 

Balance at 30 November 2016

7,196,010 (10,345,513)

6,144,357

90,692

1,500,000

417,585 5,003,131 

Profit for the year

–

1,907,441

–

10,200

Issues of shares during the year

23,343

Share options and warrants

Non-controlling Interest

Cancellation of shares  
during the year

–

–

–

–

–

135,361

–

–

–

–

–

(90,692)

–

(5,632,725)

5,632,725

–

–

–

–

–

– 1,917,641 

–

158,704 

56,932

56,932 

–

–

(90,692) 

– 

Balance at 30 November 2017

1,586,628

(2,805,347)

6,279,718

10,200

1,500,000

474,517 7,045,716 

Loss for the year

–

(1,919,276)

–

26,697

Issues of shares during the year

107,860

Share options and warrants

Cancellation of share  
premium account

–

–

–

–

1,673,157

–

6,348,971

(6,348,971)

–

–

–

–

–

–

–

– (1,892,579) 

– 1,781,017 

128,222

128,222 

–

– 

Balance at 30 November 2018

1,694,488

1,624,398

1,603,904

36,897

1,500,000

602,739 7,062,376 

Share capital is the amount subscribed for shares at nominal value. Share premium represents amounts subscribed for share capital 
in excess of nominal value, net of expenses. 

Merger relief reserve arises from the 100% acquisition of OptiBiotix Limited on 5 August 2014 whereby the excess of the fair value 
of the issued ordinary share capital issued over the nominal value of these shares is transferred to this reserve in accordance with 
section 612 of the Companies Act 2006. 

Retained earnings represents the cumulative profits and losses of the Group attributable to the owners of the company. 

Share based payment reserve represents the cumulative amounts charged in respect of unsettled warrants and options issued. 

The notes on pages 33 to 53 form part of these financial statements 

Annual Report and Accounts 2018 26

 
 
Consolidated Statement of Cash Flows 

Notes

1

Cash flows from operating activities 
Cash utilised by operations
Interest received
Taxation

Net cash outflow from operating activities

Cash flows from investing activities 
Purchases of property, plant and equipment
Purchase of intangible assets
Disposal of subsidiary net of cash balances

Net cash outflow from investing activities

Cash flows from financing activities 
Share issues

Net cash inflow from financing activities

Increase/(decrease) in cash and equivalents
Cash and cash equivalents at beginning of year

Cash and cash equivalents at end of year

15

The notes on pages 33 to 53 form part of these financial statements 

Year ended
30 November 2018
£

Year ended 
30 November 2017 
£ 

(1,233,717)
169
–

(1,233,548)

(2,954)
(469,639)
–

(470,593)

1,781,017

1,781,017

76,876
1,247,431

1,324,307

(1,895,285) 
142 
141,902 

(1,753,241) 

(1,804) 
(43,381) 
(228,212) 

(273,397) 

158,703 

158,703 

(1,867,935) 
3,115,366 

1,247,431 

27

OptiBiotix Health Plc 

 
Notes to the Consolidated Statement of Cash Flows 

1. Reconciliation of loss before income tax to cash outflow from operations 

Year ended
30 November
2018 
£

Year ended 
30 November 
2017 
£ 

Operating loss                                                                                                                (1,498,896)
(Increase)/Decrease in inventories                                                                                         (21,543)
Increase in trade and other receivables                                                                                 (267,681)
Increase in trade and other payables                                                                                     281,594
Depreciation charge                                                                                                               2,187
Share Option expense                                                                                                         128,222
Amortisation of patents and development costs                                                                     139,721
Loss on disposal of tangible and intangible assets                                                                        2,679

Net cash outflow from operations                                                                                    (1,233,717)

(2,126,802) 
17,735 
(172,336) 
209,220 
6,998 
56,932 
112,968 
– 

(1,895,285) 

2. Cash and Cash Equivalents 

Cash and cash equivalents

The notes on pages 33 to 53 form part of these financial statements 

Year ended
30 November
2018
£

1,324,307

Year ended 
30 November 
2017 
£ 

1,247,431 

Annual Report and Accounts 2018 28

Company Statement of Financial Position 

ASSETS 
Non-current assets 
Investments
Other receivables

CURRENT ASSETS 
Trade and other receivables
Cash and cash equivalents

TOTAL ASSETS

EQUITY 
Shareholders’ Equity 
Called up share capital
Share premium
Merger relief reserve
Share based payment reserve
Accumulated profit

Total Equity

LIABILITIES 
CURRENT LIABILITIES 
Trade and other payables

TOTAL LIABILITIES

TOTAL EQUITY AND LIABILITIES

As at
30 November 2018
£

As at 
30 November 2017 
£ 

Notes

12
14

14
15

16

18

6,534,300
4,242,286

10,776,586

9,242
1,167,437

1,176,679

11,953,265

1,694,488
1,603,904
1,500,000
602,739
6,323,134

6,633,299 
– 

6,633,299 

2,726,860 
1,007,769 

3,734,629 

10,367,928 

1,586,628 
6,279,718 
1,500,000 
474,517 
470,658 

11,724,265

10,311,521 

229,000

229,000

56,407 

56,407 

11,953,265

10,367,928 

These financial statements were approved and authorised for issue by the Board of Directors on 26 April 2019 and were signed on 
its behalf by: 
S P O’Hara 
Director 
Company Registration no. 05880755 

The notes on pages 33 to 53 form part of these financial statements 

29

OptiBiotix Health Plc 

 
 
Company Statement of Changes in Equity 

Called up
Share
capital
£

Retained
Earnings
£

Share
Premium
£

Merger Share-based 
Payment
reserve
£

Relief 
Reserve
£

Total 
equity 
£ 

Balance at 30 November 2016

7,196,010

(8,522,570)

6,144,357

1,500,000

417,585

6,735,382 

Profit for the period

Issues of shares during the year

Share options and warrants

–

3,360,503

23,343

–

–

–

Cancellation of shares during the period

(5,632,725)

5,632,725

–

135,361

–

–

–

–

–

–

–

–

3,360,503 

158,704 

56,932

56,932 

–

– 

Balance at 30 November 2017

1,586,628

470,658

6,279,718

1,500,000

474,517 10,311,521 

Loss for the period

–

(496,495)

–

Issues of shares during the year

107,860

Share options and warrants

Cancellation of share premium account

–

–

–

–

1,673,157

–

6,348,971

(6,348,971)

–

–

–

–

–

–

(496,495) 

1,781,015 

128,222

128,222 

–

– 

Balance at 30 November 2018

1,694,488

6,323,134

1,603,904

1,500,000

602,739 11,724,265 

Share capital is the amount subscribed for shares at nominal value. Share premium represents amounts subscribed for share capital 
in excess of nominal value, net of expenses. 

Merger relief reserve arises from the 100% acquisition of OptiBiotix Limited on 5 August 2014 whereby the excess of the fair value 
of the issued ordinary share capital issued over the nominal value of these shares is transferred to this reserve in accordance with 
section 612 of the Companies Act 2006. 

Retained earnings represents the cumulative profits and losses of the Company attributable to the owners of the company. 

Share based payment reserverepresents the cumulative amounts charged in respect of unsettled warrants and options issued. 

The notes on pages 33 to 53 form part of these financial statements 

Annual Report and Accounts 2018 30

Company Statement of Cash Flows 

Notes

1

Cash flows from operating activities 
Cash utilised by operations
Interest received

Net cash outflow from operating activities
Cash flows from investing activities 
Investment in subsidiaries

Net cash outflow from investing activities

Cash flows from financing activities 
Share issues

Net cash inflow from financing activities

Increase/(decrease) in cash and equivalents
Cash and cash equivalents at beginning of year

Cash and cash equivalents at end of year

15

The notes on pages 33 to 53 form part of these financial statements 

30 November 2018
Year ended
£

30 November 2017 
Year ended 
£ 

(1,620,434)
85

(1,620,349)

(1,000)

(1,000)

1,781,017

1,781,017

159,668
1,007,769

1,167,437

(1,263,554) 
64 

(1,263,490) 

(74,895) 

(74,895) 

158,703 

158,703 

(1,179,682) 
2,187,451 

1,007,769 

31

OptiBiotix Health Plc 

 
Notes to the Company Statement of Cash Flows 

1. Reconciliation of loss before income tax to cash generated from operations 

Operating loss

(Increase)/decrease in trade and other receivables

(Decrease)/increase in trade and other payables

Share Option expense

Interest received

Impairment losses

Net cash outflow from operations

2. Cash and Cash Equivalents 

Cash and cash equivalents

The notes on pages 33 to 53 form part of these financial statements 

Year ended
30 November
2018
£

Year ended 
30 November 
2017 
£ 

(496,495)                     (462,696) 

(1,327,028)                     (838,784) 

172,593                        (18,943) 

128,222                          56,932 

197,725                                64 

99,999

(1,620,434)

– 

(1,263,554) 

As at
30 November
2018
£

1,167,437

As at 
30 November 
2017 
£ 

1,007,769 

Annual Report and Accounts 2018 32

 
 
Notes to the Financial Statements 

1. General Information 

OptiBiotix Health plc is a company incorporated and domiciled in England and Wales. Details of the registered office, the officers 
and advisers to the Company are presented on the Company information page at the start of this report. The Company’s offices are 
in York. The Company is listed on the AIM market of the London Stock Exchange (ticker: OPTI). 

The principal activity of the Group was that of research and development into microbiome modulators. 

2. Accounting Policies 

Statement of compliance 

The consolidated financial statements of OptiBiotix Health plc have been prepared in accordance with International Financial 
Reporting  Standards  (IFRS),  International  Accounting  Standards  (IASs)  and  International  Financial  Reporting  Interpretations 
Committee (IFRIC) interpretations (collectively ‘IFRS’) as adopted for use in the European Union and as issued by the International 
Accounting Standards Board and with those parts of the Companies Act 2006 applicable to companies reporting under IFRS. 

Basis of preparation 

The financial statements have been prepared under the historical cost convention. 

The principal accounting policies are summarised below. They have all been applied consistently throughout the period under 
review. 

Going concern 

The financial statements have been prepared on the assumption that the Company is a going concern. When assessing the 
foreseeable future, the Directors have looked at the budget for the next 12 months from the date of this report, the cash at bank 
available as at the date of approval of this report and are satisfied that the Group should be able to cover its quoted maintenance 
costs, other administrative expenses and its ongoing research and development expenditure. 

After making enquiries, the Directors have a reasonable expectation that the Group has adequate resources to continue in operational 
existence for the foreseeable future. Accordingly, they continue to adopt a going concern basis in preparing the annual report and 
financial statements. 

New and amended standards adopted by the Group 

There are no IFRS or IFRIC interpretations that are effective for the first time in this financial period that would be expected to have 
a material impact on the Group. 

The following new standards, amendments to standards, and interpretations have been issued, but are not effective for the financial 
period beginning 1 December 2017 and have not been early adopted: 

New Standards, amendments and interpretations issued but not effective 

                                                                                                           Application date of             Application date of  
Reference           Title                   Summary                                           standard                            Company 

IFRS 2                 Share                  Amendments to classification and         Periods commencing on       1 December 2018 
                         based payments   measurement of share-based               or after 1 January 2018 
                                                   payment transactions 

IFRS 4                 Insurance            Amendments regarding                       Periods commencing on       1 December 2018 
                         contracts             implementation of IFRS 9                     or after 1 January 2018 

IFRS 9                 Financial              Revised standard for accounting for      Periods commencing on  
                         Instruments         financial instruments                            or after 1 January 2018        1 December 2018

33

OptiBiotix Health Plc 

 
2. Accounting Policies (continued)

                                                                                                           Application date of             Application date of  
Reference           Title                   Summary                                           standard                            Company 

IFRS 15               Revenue from      Specifies how and when to recognise    Periods commencing on       1 December 2018 
                         contracts with      revenue from contracts as well as         or after 1 January 2018 
                         customers           requiring more informative and  
                                                   relevant disclosures 
IFRS 16               Lease                  IFRS 16 Leases published                      Periods commencing on       1 December 2019 
                                                                                                           or after 1 January 2019 

IAS 40                Investment          Amendment regarding the transfer       Periods commencing on       1 December 2018 
                         property             of property                                        or after 1 January 2018 

The Directors anticipate that the adoption of these Standards and Interpretations in future periods will have no material impact on 
the financial statements of the Group. 

Basis of consolidation 

The consolidated financial statements incorporate the financial statements of the company and entities controlled by the company 
(its subsidiaries) made up to 30th November each year. Control is achieved where the Company has the power to govern the financial 
and operating policies of an investee entity so as to obtain benefits from its activities. 

The results of subsidiaries acquired or disposed of during the year are included in the consolidated statement of comprehensive 
income from the effective date of acquisition or up to the effective date of disposal, as appropriate. 

Where necessary, adjustments are made to the financial statements of subsidiaries to bring their accounting policies into line with 
those used by other members of the Group. 

All intra-group transactions, balances, income and expenses are eliminated on consolidation. 

Changes in the Group’s ownership interests in subsidiaries that do not result in the Group losing control over the subsidiaries are 
accounted for as equity transactions. The carrying amounts of the Group’s interests and the non-controlling interests are adjusted 
to reflect the changes in their relative interests in the subsidiaries. Any difference between the amount by which the non-controlling 
interests are adjusted and the fair value of the consideration paid or received is recognised directly in equity and attributed to owners 
of the company. 

When the Group loses control of a subsidiary, the profit or loss on disposal is calculated as the difference between (i) the aggregate 
of the fair value of the consideration received and the fair value of any retained interest and (ii) the previous carrying amount of the 
assets (including goodwill), and liabilities of the subsidiary and any non-controlling interests. Where certain assets of the subsidiary 
are measured at revalued amounts or fair values and the related cumulative gain or loss has been recognised in other comprehensive 
income and accumulated in equity, the amounts previously recognised in other comprehensive income and accumulated in equity 
are accounted for as if the Company had directly disposed of the related assets (i.e. reclassified to profit or loss or transferred directly 
to retained earnings). 

The fair value of any investment retained in the former subsidiary at the date when control is lost is regarded as the fair value on 
initial recognition for subsequent accounting under IAS 39 “Financial Instruments: Recognition and Measurement” or, when applicable, 
the cost on initial recognition of an investment in an associate or a jointly controlled entity.

Annual Report and Accounts 2018 34

2. Accounting Policies (continued)

Business combinations 

Acquisitions of businesses are accounted for using the acquisition method. The consideration transferred in a business combination 
is measured at fair value, which is calculated as the sum of the acquisition-date fair values of the assets transferred by the Group, 
liabilities incurred by the Group to the former owners of the acquiree and the equity interests issued by the Group in exchange for 
control of the acquiree. Acquisition-related costs are recognised in profit or loss as incurred. 

At the acquisition date, the identifiable assets acquired and the liabilities assumed are recognised at their fair value at the acquisition 
date, except that: 

–

–

–

deferred tax assets or liabilities and liabilities or assets related to employee benefit arrangements are recognised and measured 
in accordance with IAS 12 Income Taxes and IAS 19 Employee Benefits respectively; 

liabilities or equity instruments related to share-based payment transactions of the acquiree or the replacement of an 
acquiree’s  share-based  payment  transactions  with  share-based  payment  transactions  of  the  Group  are  measured  in 
accordance with IFRS 2 Share-based Payment at the acquisition date; and 

assets (or disposal groups) that are classified as held for sale in accordance with IFRS 5 Non-current Assets Held for Sale and 
Discontinued Operations are measured in accordance with that standard. 

Goodwill is measured as the excess of the sum of the consideration transferred, the amount of any non-controlling interests in the 
acquiree, and the fair value of the acquirer’s previously held equity interest in the acquiree (if any) over the net of the acquisition-
date amounts of the identifiable assets acquired and the liabilities assumed. If, after assessment, the net of the acquisition-date 
amounts of the identifiable assets acquired and liabilities assumed exceeds the sum of the consideration transferred, the amount of 
any non-controlling interests in the acquiree and the fair value of the acquirer’s previously held interest in the acquiree (if any), the 
excess is recognised immediately in profit or loss as a bargain purchase gain. 

Investments in associates 

Associates are those entities in which the Group has significant influence, but not control or joint control over the financial and 
operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power 
of another entity. Investments in associates are accounted for under the equity method and are recognised initially at cost. The cost 
of the investment includes transaction costs. 

The consolidated financial statements include the Group’s share of profit or loss and other comprehensive income of equity-
accounted investees, after adjustments to align the accounting policies with those of the Group, from the date that significant 
influence commences until the date that significant influence ceases. 

When the Group’s share of losses exceeds its interest in an equity-accounted investee, the carrying amount of the investment, 
including any long-term interests that form part thereof, is reduced to zero, and the recognition of further losses is discontinued 
except to the extent that the Group has an obligation or has made payments on behalf of the investee. 

Taxation 

Income tax expense represents the sum of the tax currently payable and deferred tax. 

(i) Current tax 

Current taxes are based on the results shown in the financial statements and are calculated according to local tax rules using tax 
rates enacted or substantially enacted by the statement of financial position date. 

Income tax is recognised in the income statement or in equity if it relates to items that are recognised in the same or a different 
period, directly in equity. 

35

OptiBiotix Health Plc 

 
2. Accounting Policies (continued)

Current tax assets and liabilities for the current and prior periods are measured at the amount expected to be recovered from or 
paid to the taxation authorities. 

(ii) Deferred tax 

Deferred tax is provided, using the liability method, on temporary differences at the statement of financial position date between 
the tax base of assets and liabilities and their carrying amounts for financial reporting purposes. 

Deferred tax liabilities are recognised for all taxable temporary differences. 

Deferred tax assets are recognised for all deductible temporary differences, carry forward of unused tax assets and unused tax losses, 
to the extent that it is probable that taxable profit will be available against which the deductible temporary differenced, and the 
carrying forward or unused tax assets and unused tax losses can be utilised. 

The carrying amount of deferred tax assets is reviewed at each balance sheet date and reduced to the extent that it is no longer 
probable that sufficient taxable profit will be available to allow all or part of the deferred tax assets to be utilised. Conversely, previously 
unrecognised deferred tax assets are recognised to the extent that it is probable that sufficient taxable profit that sufficient taxable 
profit will be available to allow all or part of the deferred tax asset to be utilised. 

Deferred tax assets and liabilities are measured at the tax rates that are expected to apply to the year when the asset is realised or 
the liability is settled, based on the tax rates and tax laws that have been enacted or substantively enacted at the balance sheet 
date. 

Investments 

Investments in subsidiaries are held at cost less any impairment. 

Financial instruments 

Financial assets and financial liabilities are recognised when the Group becomes a party to the contractual provisions of the 
instrument. 

Inventory 

Inventories are stated at the lower of cost and net realisable value. Cost is determined using the first-in, first-out (FIFO) method. Net 
realisable value is the estimated selling price in the ordinary course of business, less applicable variable selling expenses. 

Trade and other receivables 

Trade and other receivables are non-derivative financial assets with fixed or determinable payments that are not quoted in an active 
market. Subsequent to the initial recognition, trade and receivables and measured at amortised cost less impairment losses for bad 
and doubtful debts, except where the receivables are interest-free loans made to related parties without any fixed repayment terms 
or the effect of discounting would be immaterial. In such cases, the receivables are stated at cost less impairment losses for bad and 
doubtful debts. 

Impairment losses for bad and doubtful debts are measured as the difference between the carrying amount of financial asset and 
the estimated future cash flows, discounted where the effect of discounting is material. 

Cash and cash equivalents 

Cash and cash equivalents include cash in hand and deposits held on call, together with other short term highly liquid investments 
which are not subject to significant changes in value and have original maturities of less than three months. 

Annual Report and Accounts 2018 36

2. Accounting Policies (continued)

Fair values 

The carrying amounts of the financial assets and liabilities such as cash and cash equivalents, receivables and payables of the company 
at the statement of financial position date approximated their fair values, due to relatively short term nature of these financial 
instruments. 

Trade and other payables 

Trade and other payables are initially recognised at fair value and thereafter stated in amortised cost, except where the payables are 
interest free loans made by related parties without any fixed repayment terms or the effect of discounting would be immaterial, in 
which case they are stated at cost. 

Impairment of non-financial assets 

At each statement of financial position date, the Group reviews the carrying amounts of its investments to determine whether there 
is any indication that those assets have suffered an impairment loss. If any such indication exists, the recoverable amount of the 
asset is estimated in order to determine the extent of the impairment loss (if any). Where the asset does not generate cash flows 
that are independent from other assets, the Group estimates the recoverable amount of the cash-generating unit to which the asset 
belongs. An intangible asset with an indefinite useful life is tested for impairment annually and whenever there is an indication that 
the asset may be impaired. 

Recoverable amount is the higher of fair value less costs to sell and value in use. In assessing value in use, the estimated future cash 
flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value 
of money and the risks specific to the asset for which the estimates of future cash flows have not been adjusted. If the recoverable 
amount of an asset (or cash-generating unit) is estimated to be less than its carrying amount, the carrying amount of the asset (cash-
generating unit) is reduced to its recoverable amount. An impairment loss is recognised as an expense immediately, unless the 
relevant asset is carried at a re-valued amount, in which case the impairment loss is treated as a revaluation decrease. 

Where an impairment loss subsequently reverses, the carrying amount of the asset (cash-generating unit) is increased to the revised 
estimate of its recoverable amount, but so that the increased carrying amount does not exceed the carrying amount that would 
have been determined had no impairment loss been recognised for the asset (cash-generating unit) in prior years. A reversal of an 
impairment loss is recognised as income immediately, unless the relevant asset is carried at a revalued amount, in which case the 
reversal of the impairment loss is treated as a revaluation increase. 

Capital management 

Capital is made up of stated capital, premium and retained earnings. The objective of the Group’s capital management is to ensure 
that it maintains strong credit ratings and capital ratios. This will ensure that the business is correctly supported and shareholder 
value is maximised. 

The Group manages its capital structure through adjustments that are dependent on economic conditions. In order to maintain or 
adjust the capital structure, the Company may choose to change or amend dividend payments to shareholders or issue new share 
capital to shareholders. There were no changes to the objectives, policies or processes during the year ended 30 November 2018. 

Equity instruments 

Equity instruments issued by the Company are recorded at the proceeds received. Incremental costs directly attributable to the 
issuance of new ordinary shares are deducted against share capital.

37

OptiBiotix Health Plc 

 
2. Accounting Policies (continued)

Share-based compensation 

The fair value of the employee and suppliers services received in exchange for the grant of the options is recognised as an expense. 
The total amount to be expensed over the vesting year is determined by reference to the fair value of the options granted, excluding 
the impact of any non-market vesting conditions (for example, profitability and sales growth targets). Non-market vesting conditions 
are included in assumptions about the number of options that are expected to vest. At each statement of financial position date, 
the entity revises its estimates of the number of options that are expected to vest. It recognises the impact of the revision to original 
estimates, if any, in the income statement, with a corresponding adjustment to equity. 

The proceeds received net of any directly attributable transaction costs are credited to share capital (nominal value) and share 
premium when the options are exercised. 

The fair value of share-based payments recognised in the income statement is measured by use of the Black Scholes model, which 
takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used in the model 
is adjusted; based on management’s best estimate, for the effects of non-transferability, exercise restrictions and behavioural 
considerations. The share price volatility percentage factor used in the calculation is based on management’s best estimate of future 
share price behaviour and is selected based on past experience, future expectations and benchmarked against peer companies in 
the industry. 

Property, plant and equipment 

Property, plant and equipment are stated at historical cost less subsequent accumulated depreciation and accumulated impairment 
losses, if any. Historical cost includes expenditure that is directly attributable to the acquisition of the items. 

Subsequent costs are included in the asset’s carrying amount or recognised as a separate asset, as appropriate, only when it is 
probable that future economic benefits associated with the item will flow to the Group and the cost of the item can be measured 
reliably. All other repairs and maintenance are charged to profit or loss during the financial period in which they are incurred. 

Depreciation on property, plant and equipment is calculated using the straight-line method to write off their cost over their estimated 
useful lives at the following annual rates: 

Computer equipment

30% 

Useful lives and depreciation method are reviewed and adjusted if appropriate, at the end of each reporting period. 

An item of property, plant and equipment is derecognised upon disposal or when no future economic benefits are expected to 
arise from the continued use of the asset. Any gain or loss arising on the disposal or retirement of an item of property, plant and 
equipment is determined as the difference between the sales proceeds and the carrying amount of the relevant asset, and is 
recognised in profit or loss in the year in which the asset is derecognised. 

Intangibles – Patents 

Separately acquired patents are shown at historical cost. Patents have a finite useful life and are carried at cost less accumulated 
amortisation. Amortisation is calculated using the straight line method to allocate the cost of the patents over their estimated useful 
life of twenty years once the patents have been granted. 

Research and Development 

Research expenditure is written off to the statement of comprehensive income in the year in which it is incurred. Development 
expenditure is written off in the same way unless the Directors are satisfied as to the technical, commercial and financial viability of 
individual projects. In this situation, the expenditure is deferred and amortised over the period during which the company is expected 
to benefit. 

Annual Report and Accounts 2018 38

2. Accounting Policies (continued)

Revenue recognition 

Revenue is recognised to the extent that it is probable that the economic benefits will flow to the company and the revenue can 
be reliably measured, regardless of when the payment is made. Revenue is measured at the fair value of the consideration received 
or receivable, excluding discounts, rebates and sales taxes or duty. 

Merger relief reserve 

The merger relief reserve arises from the 100% acquisition of OptiBiotix Limited whereby the excess of the fair value of the issued 
ordinary share capital issued over the nominal value of these shares is transferred to this reserve in accordance with section 612 of 
the Companies Act 2006. 

Critical accounting judgments and key sources of estimation uncertainty 

The preparation of the financial statements requires management to make estimates and assumptions concerning the future that 
affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the dates of the financial 
statements and the reported amounts of revenues and expenses during the reporting periods. 

The resulting accounting estimates will, by definition, differ from the related actual results. 

•

Share based payments 

•

•

The fair value of share based payments recognised in the income statement is measured by use of the Black Scholes model, 
which takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used 
in the model is adjusted; based on management’s best estimate, for the effects of non-transferability, exercise restrictions 
and behavioural considerations. The share price volatility percentage factor used in the calculation is based on management’s 
best estimate of future share price behaviour and is selected based on past experience, future expectations and benchmarked 
against peer companies in the industry. 

Amortisation 

Management have estimated that the useful life of the fair value of the patents acquired on the acquisition to be 20 years. 
Research and developments that have been capitalised in line with the recognition criteria of IAS38 have been estimated to 
have a useful economic life of 10 years. These estimates will be reviewed annually and revised if the useful life is deemed to 
be lower based on the trading business or any changes to patent law. 

Impairment Reviews 

IFRS requires management to undertake an annual test for impairment of indefinite lived assets and, for finite lived assets to 
test  for  impairment  if  events  or  changes  in  circumstances  indicate  that  the  carrying  amount  of  an  asset  may  not  be 
recoverable. Impairment testing is an area involving management judgement, requiring assessment as to whether the 
carrying value of assets can be supported by the net present value of future cash flows derived from such assets using cash 
flow projections which have been discounted at an appropriate rate. In calculating the net present value of the future cash 
flows, certain assumptions are required to be made in respect of highly uncertain matters. 

3. Segmental Reporting 

In the opinion of the Directors, the Group has one class of business, being that of research and development. The Group’s primary 
reporting format is determined by the geographical segment according to the location of its establishments. There is currently only 
one geographic reporting segment, which is the UK. All costs are derived from the single segment.

39

OptiBiotix Health Plc 

 
4. Employees and Directors 

Wages and salaries
Director’s remuneration
Director’s Fees
Social security costs
Pension costs

The average monthly number of employees during the year was as follows: 
Directors
Research and development

Directors’ remuneration and fees
Directors’ share based payments
Bonus
Pension

Total emoluments

Emoluments paid to the highest paid Director

Included on total emoluments paid to Directors are capitalised wages of £221,703. 

Year ended
30 November 2018
£

Year ended 
30 November 2017 
£ 

23,274
576,228
41,083
79,319
54,385

774,289

141,185 
463,965 
70,500 
58,456 
36,360 

770,446 

Year ended
30 November 2018
No.

Year ended 
30 November 2017 
No. 

8
2

10

6 
2 

8 

Year ended
30 November 2018
£

Year ended 
30 November 2017 
£ 

572,311
120,793
45,000
53,834

791,938

212,897

475,350 
46,173 
38,000 
35,592 

595,115 

212,800 

Annual Report and Accounts 2018 40

4. Employees and Directors (continued)

Directors’ remuneration 

Details of emoluments received by Directors of the Group for the year ended 30 November 2018 are as follows: 

A Reynolds*
S P O’Hara
G Barker*
M Christie
R Davidson
S Kolyda
P Wennström*
P Rehne
C Wood

Total

Remuneration,
Pension and fees
£

Share based  
payments
£

5,083
212,897
18,000
5,603
50,417
87,187
18,000
144,054
129,904

671,145

–
–
13,710
2,185
7,429
21,139
–
38,165
38,165

120,793

Total 
£ 

5,083 
212,897 
31,710 
7,788 
57,846 
108,326 
18,000 
182,219 
168,069 

791,938 

*For disclosure in relation to Directors’ fees please refer to note 20. 

5. Net Finance Income/(Costs) 

Year ended
30 November 2018
£

Year ended 
30 November 2017 
£ 

169

–

169

142 

(6,154) 

(6,012) 

Finance Income: 
Bank Interest
Finance Costs: 
Loan interest

Net Finance Income/(Costs)

41

OptiBiotix Health Plc 

 
6. Expenses – analysis by nature 

Research and development
Directors’ fees & remuneration (Note 4)
Wages and Salaries
Staff training and recruitment
Auditor remuneration – audit fees (Company only nil (2017: £16,000))
Auditor remuneration – non audit fees
Brokers & Advisors
Advertising & marketing
Share based payments charge
Depreciation on property, plant and equipment
Amortisation of patents and development costs
Patent and IP costs
Consultancy fees
Legal and professional fees
Public Relations costs
Travel costs
Other expenses

Year ended
30 November 2018
£

Year ended 
30 November 2017 
£ 

160,673
449,442
–
–
50,984
2,309
86,414
48,201
128,222
2,187
139,721
88,003
146,559
26,563
152,082
120,541
248,502

302,392 
513,350 
141,185 
57,678 
34,000 
2,300 
71,360 
73,728 
56,932 
6,998 
112,969 
129,043 
202,838 
130,729 
43,860 
79,400 
285,407 

Total administrative expenses

1,850,403

2,244,169 

7.

Income Tax 

Year ended
30 November 2018
£

Year ended 
30 November 2017 
£ 

Corporation tax credit                                                                                                       (120,000)
Corporation tax credit prior year                                                                                                   –
Deferred tax movement                                                                                                        62,069
Overseas tax suffered                                                                                                             3,560

Total taxation                                                                                                                      (54,371)

(183,951) 
(21,902) 
(22,594) 
– 

(228,447) 

Annual Report and Accounts 2018 42

7.

Income Tax (continued)

Analysis of tax expense 

No  liability  to  UK  corporation  tax  arose  on  ordinary  activities  for  the  year  ended  30  November  2018  nor  for  the  year  ended 
30 November 2017. 

Year ended
30 November 2018
                                                                                                                                                  £

Year ended 
30 November 2017 
£ 

Profit (Loss) on ordinary activities before income tax                                                          (1,946,950)

1,689,194 

Loss on ordinary activities multiplied by the standard rate of corporation  
tax in UK of 19.33% (2017 – 19.33%)                                                                                  (376,345)

Effects of: 
Disallowables
Income not taxable
R&D enhanced deductions
Effect of research & development tax credit
Capital allowances
Amortisation
Revenue items capitalised
Overseas tax suffered
Other timing differences
Unused tax losses carried forward

Tax credit

62,061
–
(122,086)
(120,000)
571
27,008
(90,395)
3,560
62,069
500,372

(54,371)

326,521 

124,946 
(793,300) 
(138,607) 
(205,854) 
– 
843 
(991) 
– 
(22,594) 
480,589 

(228,447) 

The Group has estimated losses of £1,646,423 (2017: £1,760,341) and estimated excess management expenses of £2,093,197 (2017: 
£2,091,815). 

The tax losses have resulted in a deferred tax asset at 19% of approximately £710,528 (2017: £732,676) which has not been recognized 
as it is uncertain whether future taxable profits will be sufficient to utilise the losses. 

2018
£

183,952
120,000

303,952

2017 
£ 

– 
183,952 

183,952 

Current tax asset – Group 
Balance brought forward
Research & development tax credit claimed

Balance carried forward

43

OptiBiotix Health Plc 

 
8. Earnings per Share 

Basic earnings per share is calculated by dividing the earnings attributable shareholders by the weighted average number of ordinary 
shares outstanding during the period. 

Reconciliations are set out below: 

                                                                                                                                  2018 

Basic and diluted EPS

Basic EPS
Diluted EPS

Earnings
£

(1,919,276)
(1,919,276)

Weighted average 
Number of shares
No.

Profit per-share 
Pence 

82,233,690                          (2.33)p 
82,233,690                          (2.33)p 

                                                                                                                                  2017 

Basic EPS
Diluted EPS

Earnings
£

1,907,641
1,907,641

Weighted average 
Number of shares
No.

78,586,791
87,831,953

Profit per-share 
Pence 

2.43 
2.17 

As  at  30  November  2018  there  were  6,041,057  (2017:  7,845,237)  outstanding  share  options  and  1,045,524  (2017:  1,399,925) 
outstanding share warrants. As the Group was loss making in the year, the options and warrants are considered anti-dilutive. 

9. Company’s result for the year 

The Company has elected to take the exemption under section 408 of the Companies Act 2006 not to present the parent Company 
income statement account. 

The loss for the parent Company for the year was £496,495 (2017: Profit £3,360,503). 

Annual Report and Accounts 2018 44

Development  
Costs and  
Patents 
£ 

2,421,582 
43,382 
(198,834) 

2,266,130 
467,639 
(6,763) 

2,727,006 

225,936 
112,968 

338,904 
139,721 
(4,708) 

473,917 

2,253,089 
1,927,226 

10. Intangible assets 

Group

Cost 
At 1 December 2016
Additions
Disposals

At 30 November 2017
Additions
Disposals

At 30 November 2018

Amortisation 
At 1 December 2016
Amortisation charge for the year

At 30 November 2017
Amortisation charge for the year
Eliminated on disposal

At 30 November 2018

Carrying amount 
At 30 November 2018
At 30 November 2017

45

OptiBiotix Health Plc 

 
11. Property, plant and equipment 

Cost 

At 30 November 2016
Additions

At 30 November 2017
Additions
Disposals

At 30 November 2018

Depreciation 
At 30 November 2016
Charge for the year

At 30 November 2017
Charge for the year
Eliminated on disposal

At 30 November 2018

Carrying amount 
At 30 November 2018
At 30 November 2017

12. Investments 

Group 
£ 

13,615 
1,804 

15,419 
2,954 
(9,912) 

8,461 

1,860 
6,998 

8,858 
2,187 
(5,727) 

5,318 

3,143 
6,561 

Set out below is the associate of the Group as at 30 November 2018 which is material to the Group. The entity listed below have 
share capital consisting solely of ordinary shares, which are held by the Group. The country of incorporation is also the principal 
place of business and the proportion of ownership interest is the same as the proportion of voting rights held. 

Group: Investments in associate undertakings 

Cost 
At 30 November 2017
Share of Loss

At 30 November 2018

Carrying amount 
At 30 November 2018
At 30 November 2017

£ 

4,189,022 
(448,223) 

3,740,799 

3,740,799 
4,189,022 

Annual Report and Accounts 2018 46

12. Investments (continued)

As at 30 November 2018, the Group directly held the following associates: 

                                                                                                      Country of
                                                                                                      incorporation
Name of company                              Principal activities                    and place of business

Proportion of 
equity interest 
2018 

SkinBioTherapeutics Plc                       Research & Development          United Kingdom

41.9% of ordinary shares 

Company: Investments in subsidiary undertakings 

Cost 
At 30 November 2016
Additions
Disposals

At 30 November 2017
Additions
Impairments

Carrying amount 
At 30 November 2018
At 30 November 2017

£ 

2,735,100 
74,999 
(660,100) 

2,149,999 
1,000 
(99,999) 

2,051,000 
2,149,999 

The additions are in respect of 100% of the share capital of ProBiotix Health Limited. 

As at 30 November 2018, the company directly held the following subsidiaries: 

                                                                                                      Country of
                                                                                                      incorporation
Name of company                              Principal activities                    and place of business

Proportion of 
equity interest 
2017 

OptiBiotix Limited                              Research & Development          United Kingdom

100% of ordinary shares 

The Healthy Weight Loss                     Health foods                            United Kingdom
Company Limited 

68% of ordinary shares 

ProBiotix Health Ltd                           Health foods                            United Kingdom

100% of ordinary shares 

Investments in associate

At 30 November 2018
At 30 November 2017

Total Investment 
At 30 November 2018
At 30 November 2017

47

OptiBiotix Health Plc 

£ 

4,483,300 
4,483,300 

6,534,300 
6,633,299 

 
13. Inventories 

                                                                                                  Group                                                Company 
                                                                                    2018                        2017                        2018
                                                                                         £                             £                             £

Finished goods                                                             30,433                       8,890                             –

2017 
£ 

– 

14. Trade and other Receivables 

                                                                                                  Group                                                Company 
                                                                                    2018                        2017                        2018
                                                                                         £                             £                             £

2017 
£ 

Non-current 
Amounts owed by Group undertakings                                   –                             –                 4,242,286

                                                                                          –                             –                 4,242,286

Current 
Accounts receivable                                                    228,825                     20,249                             –
Amounts owed by group undertakings                                    –                             –                             –
Other receivables                                                         52,190                     77,275                         969
Prepayments and accrued income                                  92,788                       8,598                       8,283

                                                                                373,803                   106,122                       9,242

– 

– 

– 
2,645,210 
73,992 
7,658 

2,726,860 

15. Cash and Cash Equivalents 

                                                                                                  Group                                                Company 
                                                                                    2018                        2017                        2018
                                                                                         £                             £                             £

2017 
£ 

Cash and bank balances                                            1,324,307                 1,247,431                 1,167,437

1,007,769 

16. Called Up Share Capital 

Issued share capital comprises: 

Ordinary shares of 2p each – 84,724,413 (2017: 79,331,477)

2018
£

1,694,488

1,694,488

2017 
£ 

1,586,628 

1,586,628 

Annual Report and Accounts 2018 48

16. Called Up Share Capital (continued)

During the year the company issued the ordinary shares of £0.02 each listed below, exercised at a price of £0.08 per share in the 
capital of the company following the exercise of warrants: 

Total warrants exercised in the year

Date issued

14/12/2017
30/01/2018
13/09/2018

Number 

73 
354,162 
166 

354,401 

During the year the Company issued the ordinary shares of £0.02 each listed below, exercised at the following prices per share in 
the capital of the company following the exercise of share options: 

Total options exercised in the year

Date issued

06/02/2018
19/06/2018
11/10/2018

Number

800,000
1,461,408
357,772

2,619,180 

Price Per Share 

£0.08 
£0.08 
£0.20 

During the year the Company issued new ordinary shares of £0.02 at the following price per share: 

Date issued

30/05/2018

Number

2,419,355

Price Per Share 

£0.62 

The ordinary shares are non-redeemable and provide holders with one vote per share on a vote at a company meeting. They also 
provide one equal right per share in any ordinary dividend declared and one equal right per share in the distribution of any surplus 
due to the ordinary shareholders on a winding up. 

17. Reserves 

Merger relief reserve arises from the 100% acquisition of OptiBiotix Limited on 5 August 2014 whereby the excess of the fair value 
of the issued ordinary share capital issued over the nominal value of these shares is transferred to this reserve in accordance with 
section 612 of the Companies Act 2006. 

Retained earnings represents the cumulative profits and losses of the Group attributable to the owners of the Company. 

Share based payment reserve represents the cumulative amounts charged in respect of unsettled warrants and options issued. 

49

OptiBiotix Health Plc 

 
18. Trade and other payables 

Current: 
                                                                                                  Group                                                Company 
                                                                                    2018                        2017                        2018
                                                                                         £                             £                             £

Accounts Payable                                                        115,697                     10,136                             –
Accrued expenses                                                      207,103                   210,965                     30,000
Amount due to Director                                                   189                         189                             –
Other payables                                                           198,000                     18,105                             –
Amounts due to Group undertakings                                     –                             –                   199,000

Total trade and other payables                                     520,989                   239,395                   229,000

2017 
£ 

– 
56,407 
– 
– 
– 

56,407 

19. Deferred Tax 

Deferred tax is provided, using the liability method, on temporary differences at the statement of financial position date between 
the tax base of assets and liabilities and their carrying amounts for financial reporting purposes. 

Deferred tax is calculated in full on temporary differences under the liability method using a tax rate of 19% (2017: 20%). 

The movement on the deferred tax account is as shown below: 

At 30 November
Movement in the year

At 30 November

2018
£

384,092
62,069

441,161

2017 
£ 

406,686 
(22,594) 

384,092 

Deferred tax assets have not been recognised in respect of tax losses and other temporary differences giving rise to deferred tax 
assets as the Directors believe there is uncertainty whether the assets are recoverable. 

20. Related Party Disclosures 

During the year 30 November 2018 the Group was charged £5,083 (2017 – £35,500) by Reyco Limited, a company controlled by A 
Reynolds. £18,000 (2017 – £12,000) was paid to both G Barker and P Wennström in respect of Director’s services provided. 

During the year 30 November 2018 the Group was charged £36,167 (2017 – £35,000) for services provided by Morrison Kingsley 
Consultants Limited, a company controlled by Mark Collingbourne, Chief Financial Officer. 

21. Ultimate Controlling Party 

No one shareholder has control of the company. 

22. Share Based payment Transactions 

(i) Share options 

The Company had introduced a share option programme to grant share options as an incentive for employees of the former 
subsidiaries. 

Each share option converts into one ordinary share of the company on exercise. No amounts are paid or payable by the recipient 
on receipt of the option and the company has no legal obligation to repurchase or settle the options in cash. The options carry 

Annual Report and Accounts 2018 50

22. Share Based payment Transactions (continued)

neither rights to dividends nor voting rights prior to the date on which the options are exercised. Options may be exercised at any 
time from the date of vesting to the date of expiry. 

Movements in the number of share options outstanding and their related weighted average exercise prices are as follows: 

                                                                                       Number of options                                 Average exercise price 
                                                                                    2018                        2017                        2018
                                                                                      No.                         No.                             £

2017 
£ 

Outstanding at the beginning of the period                 7,845,237               10,345,237                         0.17
Granted during the year                                              815,000                 1,000,000                         0.76
Forfeited/cancelled during the year                                         –                 (666,667)                             –
Exchanged for shares                                               (2,619,180)             (2,833,333)                         0.10

Outstanding at the end of the period                         6,041,057                 7,845,237                         0.17

0.11 
0.70 
0.27 
0.10 

0.17 

For the share options issued in 2014 vesting conditions dictate that half will vest if the middle market quotation of an existing 
Ordinary share is 16p or more on each day during any period of at least 30 consecutive Dealing days and half will vest when a 
commercial contract is signed. The two conditions are not dependent on each other and will vest separately. 

For the share options issued in 2015 year vesting conditions dictate that some of the options will vest if the middle market quotation 
of an existing Ordinary share is 40p or more on each day during any period of at least 30 consecutive Dealing days, and some will 
vest if certain revenue targets are met or if certain scientific studies are completed. The conditions are not dependent on each other 
and will vest separately. 

For the share options issues in 2017 vesting conditions dictate that the options will vest if certain revenue conditions are met. 

For the share options issued in 2018 vesting conditions dictate that the options will vest if certain revenue conditions are met. 

The share options outstanding at the period end had a weighted average remaining contractual life of 2,146 days (2017 – 2,511 
days) and the maximum term is 10 years. 

The fair values of the share options issued in the year were derived using the Black Scholes model. The following assumptions were 
used in the calculations: 

Grant date

Exercise price
Share price at grant date
Risk-free rate
Volatility
Expected life
Fair value

Grant date

Exercise price
Share price at grant date
Risk-free rate
Volatility
Expected life
Fair value

51

OptiBiotix Health Plc 

13/07/2018 

73.00p 
76.00p 
0.25% 
35% 
10 years 
25.00p 

21/09/2018 

95.00p 
96.90p 
0.25% 
35% 
10 years 
34.00p 

 
22. Share Based payment Transactions (continued)

The share price per share at 30/11/2018 was £0.92 (30/11/2017: £0.69) 

Expected volatility is based on a best estimate for an AIM listed entity. The expected life used in the model has been adjusted, based 
on management’s best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations. 

(ii) Warrants 

On 20 February 2014, an open offer was made to the potential investors to subscribe for 203,380,942 new ordinary shares of £0.0001 
each at £0.0001 each. On a 1:1 basis, warrants attach to any shares issued under the open offer convertible at any time to 30 November 
2018 at £0.0004 per shares. 

On 4 August 2014, the warrants in issue were consolidated in the ratio of 200:1 as part of the share reorganisation. 

At a meeting of warrant holders on 24 January 2017 it was agreed to extend the exercise period for all remaining warrants to 
28 January 2022 and 19 February 2022. 

Movements in the number of share warrants outstanding and their related weighted average exercise prices are as follows: 

                                                                                      Number of warrants                                Average exercise price 
                                                                                    2018                        2017                        2018
                                                                                      No.                         No.                             £

2017 
£ 

Outstanding at the beginning of the period                 1,399,925                 1,983,709                         0.08
Exchanged for shares                                                 (354,401)                 (583,784)                        0.08

Outstanding at the end of the period                         1,045,524                 1,399,925                         0.08

0.08 
0.08 

0.08 

A charge of £128,222 (2017: £56,932) has been recognised during the year for the share based payments over the vesting period. 

23. Financial Risk Management Objectives and Policies 

The Group’s financial instruments comprise cash balances and receivables and payables that arise directly from its operations. 

The main risks the Group faces are liquidity risk and capital risk. 

The Board regularly reviews and agrees policies for managing each of these risks. The Group’s policies for managing these risks are 
summarised below and have been applied throughout the period. The numerical disclosures exclude short-term debtors and their 
carrying amount is considered to be a reasonable approximation of their fair value. 

Interest risk 

The Group is not exposed to significant interest rate risk as it has limited interest bearing liabilities at the year end. 

Credit risk 

The Group is not exposed to significant credit risk as it did not make any credit sales during the year. 

Liquidity risk 

Liquidity risk is the risk that Group will encounter difficulty in meeting these obligations associated with financial liabilities. 

The responsibility for liquidity risks management rest with the Board of Directors, which has established appropriate liquidity risk 
management framework for the management of the Group’s short term and long-term funding risks management requirements. 

During the period under review, the group has not utilised any borrowing facilities. 

Annual Report and Accounts 2018 52

23. Financial Risk Management Objectives and Policies (continued)

The group manages liquidity risks by maintaining adequate reserves and reserve borrowing facilities by continuously monitoring 
forecast and actual cash flows, and by matching the maturity profiles of financial assets and liabilities. 

Capital risk 

The Group’s objectives when managing capital are to safeguard the ability to continue as a going concern in order to provide returns 
for shareholders and benefits to other stakeholders and to maintain an optimal capital structure to reduce the cost of capital. 

24. Post Balance Sheet Events 

On 24 January 2019 the Company issued and allotted 7,813 ordinary shares of 2 pence each exercised at a price of 8 pence per 
share in the capital of the Company following the exercise of warrants. 

ProBiotix Health Limited (“the subsidiary”) obtained loans totalling £198,000 during 2018, in respect of convertible loan notes that 
were issued on 11 December 2018. The issue was for a total of £1.025 million, of which £725,050 was for cash consideration. £250,000 
was paid to OptiBiotix Health plc for assets transferred, and £50,000 were paid in lieu of commission costs.

53

OptiBiotix Health Plc 

 
optibiotix.com

To find out more please contact OptiBiotix on:

  info@optibiotix.com

OptiBiotix Health Plc  |  Innovation Centre, Innovation Way, Heslington, York, YO10 5DG, UK.

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