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OptiBiotix Health Plc

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FY2022 Annual Report · OptiBiotix Health Plc
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optibiotix.com

ANNUAL REPORT AND ACCOUNTS 

FOR THE YEAR ENDED 31 DECEMBER 2022

Contents 

Company Information

Chairman’s and Chief Executive’s Report

Strategic Report

Directors’ Report

Independent Auditor’s Report

2  

3 

9 

14 

 17 

Consolidated Statement of  
Comprehensive Income

Consolidated Statement of  
Financial Position

Consolidated Statement of  
Changes in Equity

22  

23 

24   

Consolidated Statement of Cash Flows

25 

Notes to the Consolidated Statement  
of Cash Flows

26 

Company Statement of Financial Position 27 

Company Statement of Changes in Equity 28 

Company Statement of Cash Flows

29 

Notes to the Company Statement of  
Cash Flows

Notes to the Financial Statements

30 

31  

1

OptiBiotix Health Plc 

 
Company Information 

Directors:                                                                                                 S P O’Hara 
                                                                                                                      R Davidson 
                                                                                                                      M Christie 
                                                                                                                      C Brinsmead 
                                                                                                                      S Hammond 
                                                                                                                      S Kolyda 

Secretary:                                                                                                 Mark Collingbourne 

Registered number:                                                                             05880755 (England & Wales) 

Registered office:                                                                                  Innovation Centre 
                                                                                                                      Innovation Way 
                                                                                                                      York 
                                                                                                                      YO10 5DG 

Auditors:                                                                                                   Jeffreys Henry LLP 
                                                                                                                      Finsgate 
                                                                                                                      5-7 Cranwood Street 
                                                                                                                      London 
                                                                                                                      EC1V 9EE 

Nominated adviser:                                                                             Cairn Financial Advisers LLP 
                                                                                                                      9th Floor 
                                                                                                                      107 Cheapside 
                                                                                                                      London 
                                                                                                                      EC2V 6DN 

Brokers:                                                                                                    Peterhouse Capital Limited 
                                                                                                                      80 Cheapside 
                                                                                                                      London 
                                                                                                                      EC2V 6DZ 

Website Address:                                                                                  www.optibiotix.com

Annual Report and Accounts 2022  2

Chairman’s and Chief Executive’s Report 
For the year ended 31 December 2022

approvals 

The Group addresses a very large and fast-growing market with 
a unique portfolio of proven ingredients and finished products. 
The year has seen progress in both scientific human studies and 
regulatory 
international  markets 
in  key 
demonstrating  our  products  effectiveness  and  global 
acceptability. After strong sales growth through 2019 (£745K), 
2020 (£1.5m) and 2021 (£2.2m) the Company expanded its team 
in 2021 including the appointment of CEO, René Kamminga to 
run the prebiotic business, to meet growth demands post Covid 
but as with many companies in the industry suffered from lower 
sales in 2022 caused by the global economic uncertainty that 
followed the Russian invasion of Ukraine.  

This was compounded by the large amount of orders placed in 
Q4  2021  resulting  in  high  stock  levels  held  by  customers 
accompanied  by  delays  in  launching  new  products  and 
re-ordering due to the global economic down turn in 2022. The 
Company  are  pleased  that  its  products  have  begun  to  be 
commercialised  by  a  number  of  large  and  well  known 
commercial partners. Agreements with these partners are time 
consuming with extensive due diligence and consumer testing 
prior  to  launch.  Launch  of  products  with  these  partners  is  a 
significant endorsement of our products which we believe in the 
absence of recent global economic events (COVID and Ukraine) 
would have led to strong revenue growth.  

Post period the Company has responded to these changes in the 
external environment by a reduction in costs, a focus on sales 
and partners delivering to forecast, and building up operational 
resilience  by  broadening  its  partner  base  and  building  its 
ecommerce  channels  to  reduce  partner  dependency.  The 
Company  believes  subject  to  no  significant  change  to  the 
external environment these measures will return the business 
to the high levels of growth and EBITDA profitability achieved 
in 2020 and 2021. The Group remains financially robust with no 
debt, and valuable assets in SkinBiotherapeutics and ProBiotix 
Health providing a strong balance sheet, with commercialisation 
of our second-generation technologies affording potential for 
future growth and shareholder value. 

Strategic overview 

is  a 

OptiBiotix  Health 
life  sciences  business  founded  on  the 
development of prebiotic and probiotic compounds to tackle obesity, 
cardiovascular disease, diabetes and skincare: all markets offering strong 
growth potential in every part of the world. The Company has built a 
broad portfolio of microbiome assets in this field including prebiotic 
products like SlimBiome®, WellBiome®, SweetBiotix®, and Microbiome 
modulators  within 
through 
SkinBiotherapeutics  and  probiotics  through  ProBiotix  Health  Plc. 
These create a diverse portfolio of opportunities in an emerging area 
of healthcare.  

its  core  business  and  skincare 

333

OptiBiotix Health Plc 

The first phase of the Companys’ two-stage growth strategy was to 
establish the credibility of our science and financial sustainability of each 
business through an initial focus on building sales of our first-generation 
products (principally SlimBiome® in prebiotics and LPLDL® in probiotics) 
though business-to-business deals with partners in multiple territories 
around the world, starting in Europe, while at the same time pursuing 
the development of our more innovative second-generation products 
that offer potentially larger future returns. This was achieved in 2020 
and 2021 with combined revenues of £2.2m and both the Probiotic 
(now  ProBiotix  Health  Plc)  and  Prebiotic  trading  businesses  being 
EBITDA profitable in both years and the Group showing a £5.8m profit 
in 2020 and £6.2m in 2021, albeit largely due to the gain in the value of 
its investments.  

With SlimBiome® and LPLDL® winning international awards, gaining 
excellent  customer  reviews,  and  becoming  established  ingredient 
brands with a number of key national and international partners in 2019 
we started to move towards developing and testing market acceptance 
of our own label branded products (e.g GoFigure, SlimBiome Medical, 
and CholBiomeX3) on our online store. The aim was to use the online 
store as a display window to attract B2B partners and major retailers and 
assess the potential of selling final products direct to consumers. With 
positive customer feedback on our own products and more consumers 
buying online as a result of the COVID pandemic (Mintel, Vitamins and 
Supplements: Inc Impact of COVID-19 - US, August 2020) a decision was 
made in 2021 to develop this into a business unit with the appointment 
of a E-commerce director. This was one of a number of changes made 
in 2022 to allow the Company to respond to changes in the external 
environment. These also included: 

•

•

•

•

Gradually moving from ingredient sales to the sale of finished own 
brand SlimBiome Medical or private label products, both through 
larger partners and direct-to-consumer through our own online 
store, Amazon, and other outlets such as Tmall.com in Asia. This 
increases margins and reduces partner dependency.  

Shifting the focus from Europe to large partners in key strategic 
markets, particularly the USA and Asia. This broadens the partner 
base and reduces revenue dependency on a small number of 
partners whilst accessing larger markets with substantially higher 
sales volumes. 

Expanding our first-generation product portfolio of functional 
ingredients by extending our technology into new channels such 
as sports nutrition with LeanBiome® and new product areas such 
as WellBiome®, and 

Progressing  the  commercialisation  of  our  second-generation 
products, SweetBiotix® and Microbiome Modulators. 

This was accompanied by a number of new appointments throughout 
2022 in marketing, business development in the USA, and e-commerce 
to support growth of the business. Whilst global economic conditions 

 
Chairman’s and Chief Executive’s Report (continued)

temporarily impacted on progress during 2022 we believe the changes 
made  in  2022  increase  the  Company’s  resilience  to  volatility  in  the 
external environment and are seeing sales slowly returning to previous 
forecast levels as market conditions improve. The other key point is that 
now we have established the SlimBiome® brand and OptiBiotix’s market 
credibility customers are starting to place orders without having to go 
through a complex negotiation process.  

Commercial and scientific overview 

Key  developments  during  the  financial  year  and  their  impact  on 
potential sales growth in 2023 include: 

•

•

•

The achievement in January 2022 of British Retail Consortium 
accreditation, confirming our compliance with the Global Food 
Safety Initiative (‘GFSI’) benchmark. This certification by one of the 
leading international food safety standards, accepted by most 
large  retailers  and  their  suppliers  worldwide,  is  an  important 
support to our commercial strategy of increasing our sales of final 
product solutions to retail partners and will enhance opportunities 
in  other  retail  channels  both  within  the  UK  and  international 
markets. 

Our  entry  into  the  sports  nutrition  market  with  the  launch  of 
LeanBiome®, a patented blend of dietary and prebiotic fibres and 
a  trace  mineral,  developed  to  support  athletes  increase  lean 
muscle mass and to improve metabolism, gut health and satiety. 
Our distribution agreement with leading e-commerce retailer The 
Hut  Group  PLC  (“THG”),  signed 
in  December  2021,  saw 
LeanBiome®  launched  in  January  2022  in  a  small  number  of 
products including its Impact Diet Lean product as part of its My 
Protein range in the UK and at the end of H1 2022 a product 
extension with a breakfast smoothie. Both products are receiving 
excellent  customer  reviews.  High  inflation  in  2022  led  to 
consumers becoming more price-conscious leading to a trading 
down  of  high  protein  products  which  reduced  the  forecast 
demand  for  protein  powder  shakes  across  the  industry  and  a 
lower than forecast sales from THG. With protein prices slowly 
returning to previous levels we are seeing a gradual return to sales 
growth in this area. 

Prior to ProBiotix’s separate listing, publication in January 2022 of 
a third human volunteer study on the clinical efficacy of LPLDL®, 
demonstrating through a placebo-controlled trial that LPLDL® 
delivered  large  and  statistically  significant  reductions  in  total 
cholesterol, LDL-C (bad) cholesterol and Apolipoprotein B (widely 
accepted as the most important causal agent of atherosclerotic 
cardiovascular disease), with no compliance, tolerance or safety 
issues. The results of this and other studies suggest efficacy similar 
to low level statins and other treatments more typically associated 
with  pharmaceuticals,  suggesting  potential  in  high  value 
pharmaceutical  consumer  markets  for  the  use  of  LPLDL® 

•

•

•

•

•

•

•

individuals  who  are  unwilling  or  unable  to  tolerate 

in 
other treatments.  

Admission of ProBiotix Health Plc to the AQSE Growth Market on 
31 March 2022, raising £2.5m for the further development of our 
former Probiotic subsidiary through a placing and subscription of 
new  shares,  while  giving  our  own  shareholders  a  dividend  in 
specie of 0.554673 ProBiotix share for every OptiBiotix Health share 
held. The Group retained a 44% shareholding in ProBiotix Health, 
valued  at  circa  £11.2m  at  the  end  of  2022.  An  impairment 
provision (see note 11) has been made to take account of the 
reduction in PBX share price from 31st March 2022 and the release 
of these accounts.  

Good progress in the development of OptiBiotix Health India. Its 
formation has allowed us to reduce the administrative and tax 
burden of manufacturing and selling ingredients and finished 
products in India. We see the lower manufacturing and transport 
costs with geographical proximity to the countries in the region 
a driver of future growth in the Asia Pacific region.  

Certification  in  June  2022  of  LeanBiome®  as  an  Informed 
Ingredient for Sports Nutrition: an important industry certification 
demonstrating  through  rigorous  independent  testing  by  an 
authorised body that it is free from substances that are banned in 
sport. This is a significant step in attracting major sports nutrition 
companies to incorporate LeanBiome® in their products. 

The appointment in September 2022 of Nutraconnect Pte Ltd, a 
nutraceutical business growth acceleration service headquartered 
in Singapore, as a new commercialisation partner for SlimBiome® 
and  LeanBiome®  in  the  Asia  Pacific  region.  This  has  led  to  a 
number of new partners signing agreements and placing first 
orders for products in 2023.  

The launch in September 2022 of our GoFigure range of weight 
management  products  containing  SlimBiome® 
in  several 
pharmacies across India owned by Apollo Hospitals & Pharmacies. 
This number has doubled in 2023 with the aim of having products 
in more than 1000 stores by the end of 2023.  

Regulatory approval in October 2022 by the Saudi Food & Drug 
Authority (SFDA) for the sale by our exclusive distributor Nahdi 
Medical  Co  (Nahdi)  of  GoFigure  shakes  and  bars  containing 
SlimBiome®. This has allowed the launch in January 2023 of the 
GoFigure range of weight management products through Nahdi’s 
pharmacy network and e-commerce platform. The registration 
process also provides approval in the other five countries that are 
members of the Gulf Cooperation Council. 

Completion  in  October  2022  of  a  systematic  review  of  the 
scientific literature relating to SlimBiome®, in accordance with the 
Australia New Zealand Food Standards Code (FSANZ), that enables 
us to make four new health claims for SlimBiome® on product 

Annual Report and Accounts 2022 4
Annual Report and Accounts 2022

Chairman’s and Chief Executive’s Report (continued)

•

•

•

•

•

packaging and in advertising; these relate to feelings of fullness, 
reduction of hunger, and improvement of the gut microbiome 
and  improving  digestive  health.  These  help  us  to  differentiate 
SlimBiome® from competitors.  

Launch in late November 2022 of an online shop for GoFigure 
products  containing  SlimBiome®  on  a  leading  e-commerce 
platform  in  China,  Tmall.com,  allowing  us  to  sell  direct  to 
consumers in this huge and growing market. We are seeing steady 
sales  growth 
in  2023,  particularly  of  our 
fruit gummies. 

in  this  market 

Publication of a peer-reviewed study (see Prebiotic Potential of a 
New Sweetener Based on Galactooligosaccharides and Modified 
Mogrosides  –  PubMed  (nih.gov))  of  one  of  our  SweetBiotix® 
products confirming its sweetness, bulking and prebiotic fibre 
properties  and  concluding  it  could  be  an  innovative,  healthy 
substitute for sugar in a range of everyday products. Independent 
scientific confirmation of SweetBiotix® by leading scientists in the 
field is key to creating interest and industry credibility and provides 
important marketing materials for commercial launches.  

Significant progress by one of our US partners in the commercial 
scale production of SweetBiotix®, with final product tested and 
accepted and now awaiting further structural analysis and formal 
taste  testing  to  determine  the  regulatory  pathway  before 
progressing to a launch. 

Conclusion of a new joint development agreement, announced 
in July 2022, with Firmenich, the world’s largest privately owned 
taste  and  fragrance  company,  and  one  of  the  world’s  largest 
supplier of Stevia, to develop new products containing our second 
generation  SweetBiotix®  compound,  in  return  for  sales-based 
milestone and royalty payments. This agreement with one of the 
leaders in the field after years of due diligence is a substantial 
validation of the SweetBiotix science. This continues to progress 
at pace in 2023. We believe that the recent scientific publication 
and the deal with Firmenich, which is merging with DSM, the 
world’s largest ingredients supplier, to create a NewCo with a US 
$11.4bn turnover, are major steps forward in bringing SweetBiotix® 
to  market.  Firmenich  is  now  making  substantial  progress  in 
producing  SweetBiotix®  and  in  optimising  the  manufacturing 
process, and we see significant opportunity here in 2023. 

Significant scientific and commercial progress in the development 
of  our  microbiome  modulators:  a  range  of  second-generation 
products which selectively enhance the growth rate of specific 
types of bacteria and create the potential for targeted treatment 
of a range of human diseases. The manufacturing scale up process 
was delayed during COVID but completed in late 2022. Structural 
and  functional  analysis  has  been  taking  place  during  2023  to 
determine novelty and the regulatory pathway.  

Results 

The  Group’s  results  reflect  its  new  structure  following  the  listing  of 
ProBiotix Health (“PBX”) on the AQSE Growth Market on 31 March 2022. 
The timing of the listing means that the accounts include the results of 
PBX for the three months to the end of March 2022 when it became a 
plc, after which PBX has been treated as an associate for accounting 
purposes with its revenues and costs removed and only OptiBiotix’s 
(44%)  proportion  of  its  profit  and  loss  included  in  the  Company’s 
accounts. This makes comparisons with previous years difficult. 

The results show revenue from continuing operations for the year of 
£457K (2021: combined sales of £2.2m), reflecting both the separate 
flotation of ProBiotix Health Plc and delays in the placement of orders 
by our new larger partners, which entered the year with substantial 
stocks from orders placed in late 2021, and then delayed re-ordering 
because of the global economic uncertainty created by the Russian 
invasion of Ukraine. 

Administrative expenses (excluding non-cash items such as share-based 
payments  and  amortisation)  were  £2.5m  (2021:  £2.1m),  including 
ProBiotix costs to the end of March and a number of one-off pre-listing 
and recruitment expenses. This includes a one off bad debt provision of 
£492K reflecting a more conservative approach to debtors and stock 
considering the volatility of the external environment. We continue to 
pursue outstanding debtors and believe a proportion of this provision 
will be recovered in 2023.  

The listing of PBX on AQSE materialised a previously unrecognised asset 
allowing the Company to report a profit of £2.47m largely from the gain 
on  this 
loss  on  revaluation  of  the 
SkinBioTherapeutics plc (“SBTX”) shares. The Group retains a healthy 
balance sheet with gross assets of £11.6m (2021: £20.1m) and net cash 
at the year-end of £1.1m (2021: £2.0m).  

investment  offset  by  a 

Post period end the Group sold 1,211,567 SBTX shares through Cenkos, 
SBTX’s broker in February 2023 at an average price of 20.4p, generating 
gross proceeds of £247K.  

The Board senior management and 
advisers 

We have taken decisive action in December 2022 and in 2023 to reflect 
the separate listing of PBX and reduce Board, management and advisory 
costs in order to ensure each part of the business and subsequently the 
Group  return  to  operational  profitability  as  soon  as  possible. These 
actions include: 

•

•

On 28 December 2022 the Company served three months’ notice 
to  terminate  the  joint  brokership  of  Cenkos  Securities  plc. 
Peterhouse Capital Limited continue as the Company’s sole broker. 

René Kamminga, who was appointed CEO of OptiBiotix Ltd in 
March 2021 left the business on 28 February 2023 and Group CEO 

5

OptiBiotix Health Plc 

 
Chairman’s and Chief Executive’s Report (continued)

Stephen O’Hara, who led the ProBiotix business in 2022, resumed 
the role of CEO of OptiBiotix Ltd. 

•

Re-engaged with major partners that underperformed against our 
sales expectations in 2022, leading to: 

•

•

All  directors  volunteered  to  accept  a  20%  reduction  in  their 
remuneration from 1 January 2023. 

With  the  departure  of  René  the  Company  has  twice  as  many 
non-executive directors as executive directors. As a result Stephen 
Hammond and Chris Brinsmead have agreed to step down at the 
Company’s upcoming Annual General Meeting in July 2023. 

We anticipate further restructuring of the board and management team 
of OptiBiotix as ProBiotix Health Plc develops its independence and we 
reduce the number of senior employees currently shared with ProBiotix 
Health Plc under shared service agreements.  

Looking ahead, the focus of the Company will be on investing in areas 
that offer the highest return. To support that process and ensure a focus 
on profitability the Company is developing profit and loss metrics for 
each  part  of  the  business  with  the  aim  of  each  area  (USA,  India, 
Ecommerce, B2B) reaching operational profitability, at least on a monthly 
basis by the end of the calendar year.  

Outlook 

Our focus in 2023 is on looking forward and moving the Company to 
operational profitability. We believe we will achieve this by a reduction 
in central costs and by the promotion of sales, both direct to consumers 
via ecommerce channels and through our existing partners delivering 
on forecasts and bringing in new customers, particularly in the USA and 
Asian  markets.  There  has  been  progress  in  each  of  these  areas  as 
outlined below which highlights some of the changes made since the 
beginning of 2023 year and provides a progress update on each of the 
business units. In the first part of 2023 we have: 

•

•

Invested  significantly  in  new  e-commerce  channels,  including 
Amazon in the UK, and Walmart in the USA, as well Tmall.com in 
China. This has led to rapid sales growth (see E-commerce report) 
which  with  continued  investment  we  anticipate  will  continue 
throughout 2023 and beyond. 

Shifted  our  commercial  focus  to  selling  SlimBiome®  Medical 
sachets in Europe and SlimBiome shots in India and the Gulf states. 
These are designed to be consumed before meals and help users 
manage their weight by making consumers feel fuller for longer 
and reducing cravings for sweet and savoury snacks. This is a highly 
differentiated product which leverages growing market interest 
in injectable appetite control drugs like semaglutide. SlimBiome® 
Medical can be used with any weight management plan or calorie 
restriction  plan  and  complements  rather  than  competes  in  a 
crowded  marketplace.  The  product  enjoys  high  margins  and 
became a top-selling line on Amazon UK in 2023. 

√

A significant new investment in marketing by Optipharm in 
Australia, coupled with the launch online of their Optislim and 
Optiman ranges containing our OptiBiome prebiotic fibre; 

√ New orders from both The Hut Group and Holland & Barrett 

in the UK and 

√

A substantial increase in the number of Apollo pharmacies 
and  Holland  and  Barret  shops  in  India  selling  GoFigure 
products accompanied by a launch of products on Amazon 
India on 16th May 2023. 

We anticipate further orders from all these partners in the second half 
of the current year. 

•

•

•

Successfully launched new products, including our reformulated 
WellBiome® functional fibre and mineral blend, which has been 
made available via our own online store and on Amazon UK in 
recent weeks. 

In the last two months recruited three new partners in Asia who 
have all placed initial orders for SlimBiome and a major US weight 
management brand, with which we will be launching during the 
second half of 2023, initially in Europe and later in the USA. 

Published the results of a third human study on SlimBiome® which 
demonstrated  statistically  significant  benefits  to  appetite  and 
hunger regulation, with no safety, compliance or tolerance issues 
reported by the participating volunteers. This study underlines the 
effectiveness of a single dose of SlimBiome® in delivering hunger-
free weight loss by non-invasive means. This study was timely 
given  the  growing  consumer,  media  and  pharmaceutical 
company interest in this field following NICE’S approval of the 
injectable drug semaglutide.  

North America Sales and Business 
Development 

The Company has received a number of orders from US partners who 
are owners of leading weight management or sports nutrition brands 
in the USA. This is a major endorsement of the products and is the result 
of  presentations  at  conferences  and  exhibitions  and  numerous 
customer  visits  by  our  US  Business  development  Director,  Zac 
Sniderman. These will show in 2023 H1 accounts if manufactured and 
delivered by the end of June or more likely H2 2023.  

Discussions are advancing with a number of international Multilevel 
Marketing (MLM) companies based in the USA with possible sales in H2 
2023 for Asian markets. Discussions with an e-commerce brand have 
continued at a steady pace in 2023 for a possible end of the year launch. 
In addition to above we have late-stage discussion with a number of 

Annual Report and Accounts 2022 6

Chairman’s and Chief Executive’s Report (continued)

e-commerce brands in both the US and Canada with potential sales in 
H2 2023.  

e-commerce  platform, T-Mall,  in  China,  particularly  with  sale  of  our 
fruit gummies. 

During  the  first  half  of  2023  we  have  seen  strong  sales  growth  of 
Dietworks Appetite Control gummies in the USA in both e-commerce 
channels and traditional retailers and we foresee increased sales in H2 
2023 with the possibility of line extensions.  

We  are  in  discussions  with  two  US  partners  who  are  interested  in 
purchasing WellBiome® with a potential US launch planned for Q4 2023. 
The new projects would incorporate WellBiome in a final product for 
healthy aging and hydration.  

Consumer Health and Ecommerce sales 

The  OptiBiotix  online  website  has  been  transitioned  from  a  shop 
window  used  to  demonstrate  product  possibilities  to  partners  to  a 
commercial  website  and  optimised  to 
improve  the  customer 
experience. The ecommerce business has opened up a number of new 
channels to market including Amazon UK and Walmart USA to allow 
customers from different locations/sites to have greater accessibility to 
our products. Increasing awareness on platforms such as Amazon UK 
have allowed brands such as SlimBiome to become a best seller within 
their respective categories. Since the end of 2022 through to April 2023 
we have focused more on promoting SlimBiome® Medical as a unique 
product which reduces hunger and cravings which can be used as part 
of any calorie restriction weight management plan. This has led to rapid 
growth with the ecommerce business reaching operational profitability 
in April and May 2023 with the highest monthly sales on record and a 
sales increase of 1,200% (Figure 1). We are seeing good growth on the 

In 2023 we plan to grow our brands presence and securing listings on 
various channels including Amazon Europe and Amazon India whilst 
pushing hard for sales and customer loyalty. The addition of WellBiome® 
to the online store in May 2023 is part of a strategy to enhance the range 
of different product offerings and products on the website throughout 
2023. Current product line extensions planned for SlimBiome® include 
a tomato and herb soup, a chicken soup, a Golden Syrup porridge, high 
protein chocolate bars and an indulgent range.  

As we add more products, open up channels to new markets, and bring 
on  new  applications  we  should  see  continued  growth  within  the 
Ecommerce business in 2023 and beyond. 

Our medical device registration for SlimBiome® Medical runs out in May 
2024. Brexit has added complexity and additional cost in reregistering a 
CE mark medical device with a £100k cost to renew the registration and 
an  annual  maintenance  cost  of  £20-30K  per  annum  per  device 
(unflavoured and flavoured SlimBiome Medical). Given the CE mark is 
only applicable in Europe and we have similar products non CE marked 
in India and the Gulf states we are seeing this as an opportunity to 
rebrand and broaden the offering with different flavours to a wider 
customer group who may be dissuaded from purchasing a product with 
a medical connotation.  

OptiBiotix Health India 

OptiBiotix Health India (“OHI”) was formed in November 2021 as a mid 
to long term strategic investment in the world’s most populous nation 
and forecast to have the highest population of medium to high level 

7

OptiBiotix Health Plc 

 
Chairman’s and Chief Executive’s Report (continued)

income customers in the world. Currently most middle-class consumers 
live in the European Union (EU) and the United States, but over the next 
decade, the majority will shift heavily toward India, with one in four 
global  middle-class  consumers  expected  to  reside  in  India  by  2035 
https://www.asianstudies.org/publications/eaa/archives/the-middle-
class-in-india-from-1947-to-the-present-and-beyond/. 

The formation of OHI has helped OptiBiotix avoid high import taxes and 
control the purchase and sale of ingredients (SlimBiome®) and final 
product ( GoFigure®) manufactured and sold in India. This has increased 
profit margins and given us a manufacturing base to export to other 
countries in Asia with lower manufacturing and transport costs than 
exporting from the UK. This will support future expansion and sales 
growth in the region. The lower costs and The ‘created in UK and made in 
India’  tag  helps  penetrate  the  market  and  makes  the  product 
viable commercially. 

We  had  two  small  customers  and  a  large  national  player  (Apollo 
Hospitals “Apollo”) in India in 2022. During 2023 we have had orders from 
a number of new customers and the launch of a new product range 
called  Slim-Pro  by  Health  Bae,  an  emerging  name  in  the  multilevel 
marketing channel (see https://health-bae.com ). Whilst these are small 
first orders they are part of building the customer base and product 
profile across India allowing us to build the business.  

After  a  slow  start  following  the  launch  of  products  with  Apollos  in 
September  2022  we  are  now  seeing  momentum  increase  with  the 
number of stores selling GoFigure products increase month on month 
with sales in April double that of March and continued strong growth 
in May 2023, with a high returning customer rate. Apollo have agreed 
to extend the product range in H2 2023. We are also pleased to be 
developing  a  product  for  the  Indian  Market  with  a  multinational 
consumer goods company for launch later in the year. 

The  fundamentals  of  our  marketplace  remain  very  exciting,  with 
modulation  of  the  human  microbiome  attracting  ever-increasing 
interest as the potential solution to a wide and growing range of life-
style related health challenges. Unique, innovative products take time 
to gain market acceptance and our first-generation products are no 
exception. We believe their strong science, clinical studies, and broad IP 
portfolio together with the industry awards and great customer reviews 
are starting to attract growing international recognition and with this 
more sales opportunities. 

After strong sales growth through 2019 (£745K), 2020(£1.5m) and 2021 
(£2.2m) we believe 2022 was an unusual year for the industry and the 
Company and that the actions we are taking to reduce costs and grow 
sales will restore the Group to operational profitability, while broadening 
our product and partner base, and increasing sales of final products 
direct to consumers. These actions will reduce the risks of revenues in 
future periods being impacted by timing differences in restocking or 
delays in individual product launches or regulatory approvals. 

Our expansion into USA and Asia, the proven credibility of our science, 
the growing number of large partners, and a return on our investment 
in 2023 from our sales teams give us continued confidence in the long-
term growth potential of the Group. 

Whilst the Board are optimistic about the opportunities for the business 
in 2023, we remain alert to the threats posed by the risks described in 
the ‘principal risks and uncertainties’ section of the Strategic Report and 
we note that future trading may be affected by these external factors.  
The group’s mitigation strategies for these principal risks are also set out 
in this section. 

We are confident that our strategy will continue to deliver sales growth 
in  2023  whilst  the  approaching  commercialisation  of  our  second-
generation SweetBiotix® family of products and microbiome modulators 
offer  exciting  potential  for  future  growth.  This  is  in  addition  to  the 
Company having a continued exposure to the considerable growth 
potential in probiotics and skincare through the Group’s shareholdings 
in ProBiotix Health Plc and SkinBiotherapeutics plc. 

N Davidson 
Chairman 

Stephen O’Hara 
Chief Executive 

23 June 2023

Annual Report and Accounts 2022 8

FINANCIAL AND CAPITAL RISK 
MANAGEMENT 

The directors constantly monitor the financial risks and uncertainties 
facing the Group with particular reference to the exposure of credit risk 
and liquidity risk. They are confident that suitable policies are in place 
and that all material financial risks have been considered. The financial 
risk management objectives and policies can be found within note 23 
of the financial statements. 

The Board’s objective is to maintain a balance sheet that is both efficient 
and delivers long term shareholder value. The Group had cash balances 
of £1.052m as at 31 December 2022 and had no short-term borrowings. 
The Board continues to monitor the balance sheet to ensure it has an 
adequate capital structure. 

Strategic Report 
For the year ended 31 December 2022

REVIEW OF BUSINESS 

A review of the business of the Group, together with comments on 
future developments is given in the Chairman’s and Chief Executive’s 
Reports on pages 3 to 8 

PRINCIPAL RISKS AND UNCERTAINTIES 
FACING THE GROUP 

Technology and products 
The Group is involved in the discovery and development of microbiome 
modulation  products.  The  development  and  commercialisation  of 
its  intellectual  property  and  future  products  will  require  human 
nutritional studies and there is a risk that products may not perform 
as expected. This risk is common to all new products developed for 
human consumption. 

Technologies  used  within  the  food,  beverage  and  healthcare 
marketplace are constantly evolving and improving. There is a risk that 
the Group’s products may become outdated or their commercial value 
decrease as improvements in technology are made and competitors 
launch competing products. To mitigate this risk the Group is working 
with industry key opinion leaders, attends international conferences and 
has developed a research and development department which will 
keep up with the latest developments in the industry. 

Intellectual Property 
The Group is focused on protecting its IP and seeking to avoid infringing 
on third parties’ IP. To protect its products, the Group is building and 
securing patents to protect its key products. However, there remains the 
risk that the Group may face opposition from third parties to patents 
that  it  seeks  to  have  granted  and  that  the  outstanding  patent 
applications  are  not  granted.  The  Group  engages  legal  advisers  to 
mitigate the risk of patent infringement and to assist with the protection 
of the Group’s IP. 

9

OptiBiotix Health Plc 

 
Strategic Report (continued)

Principal Risks And Uncertainties 

Market Risks

Impact

Mitigation 

Brexit 

New regulations, such as the Windsor protocol, could 
add complexity and delays to operations. 

The  current  consensus  is  that  the  new  regulations  will  not 
affect the regulations that are relevant to our business. 

Economic 
uncertainty caused 
by war in Ukraine

Technology 

Currency  fluctuations  could 
affect profitability.

increase  costs  and 

Currency fluctuations will impact both sales and costs. Our 
initial product offering is not price-sensitive. Substantial cost 
increases will be passed on.

Ongoing  economic  uncertainty,  recession  or  an 
escalation of the war in Ukraine may impact market 
confidence, demand and prices. 

The group is not directly affected by the war in Ukraine but the 
Board  monitor  the  general  economic  environment  and 
consider economic forecasts when taking key decisions. 

The  Group’s  platform  is  currently  unique.  Rapid 
technological advances could see competitor products 
being launched.

The Group has product development plans in place for improved 
technology as well as for a wider product portfolio that includes 
additional innovative solutions for the targeted consumer groups.

Financial Risks

Impact

Mitigation 

Future funding  
requirements 

Our  current  funding  covers  current  requirements.   
Potential as yet unidentified opportunities may not be 
pursued with the existing funding.

Management  will  analyse  major  opportunities  and  present 
them  in  additional  business  cases  when  warranted.  The 
Company is able to sell its listed investments and raise further 
equity and debt finance.

Legal Risks

Impact

Mitigation 

Intellectual  
Property litigation 

Any  claim  brought  against  us  would  detract  the 
Company  from  its  business  and  incur  potentially 
significant costs in defending its IP.

The Group engages with IP specialists to ensure we have a 
strong  position.  To  our  knowledge  we  do  not  infringe  on 
any patents.

Operational Risks

Impact

Mitigation 

Loss of key  
personnel 

Technology 

Material  adverse  impact  on  the  Group’s  financial 
condition and prospects.

Competitive remuneration packages, nil cost options to reduce 
market volatility. The remuneration committee oversees the 
level of remuneration to ensure it remains competitive

The Group is commercialising its technology to launch 
new products  in the consumer market.

The  Group  has 
consumer demand.

identified  a  need  and  responded  to 

Commercialisation 

The Group is making the transition from a research-
based organisation to a full commercial organisation. 
Manufacturing set-up and learning curve could delay 
sales or could impact our rate of growth

recruited  experienced  management  and 
The  Group 
consultants to manage the process and negotiate contracts. 
The manufacturing is outsourced.

Working capital 

The  Group  has  encouraged  customers  to  build  up 
material stocks of ingredients to meet user demand 
from end user customers. Flexible payment terms have 
been given to customers to pay for stock.  

If stocks are not used, would they become unusable.

Ingredients  have  a  three-year  shelf  life  risk  of  non-usability 
is reduced. 

As end user requirements become formalised and production 
time frames for ingredients come down it will be possible for 
Group customers to hold less stock of ingredients which will in 
turn reduce the debtor balances outstanding at period end.

Cyber attacks

Cyber-attacks could delay or impair operations as which 
would have financial implications. 

Training,  anti-virus  software,  all  users  have  multifactor 
authorisation for accounts, weekly review of attempts.

Annual Report and Accounts 2022 10

 
Strategic Report (continued)

KEY PERFORMANCE INDICATORS 
Financial 

Year to 
31 December
2022
£’000

Year to  
31 December 
2021 
£’000 

Revenue
Operating Loss
Profit/(Loss) for the period
Cash as at 31 December 

457                  2,213 
(2,489)                (1,365) 
2,587                  6,261 
2,007 
1,052

During the year to 31 December 2022 the company has achieved a 
number of key objectives to build shareholder value, these are laid out 
in the Chairman’s and Chief Executive’s report on pages 3 to 8. 

Non-financial 

The Board recognises the importance of KPI’s in driving appropriate 
behaviour  and  enabling  of  Group  performance.  For  the  year  to 
31 December 2022 the primary KPI’s were the completion of commercial 
agreements and the expansion of the Optibiotic® platform. The Group 
intends to review the following non-financial KPI’s going forward: 

1.

2.

3.

Number of Customers 

Number of IP and trademark registrations 

Rate of staff turnover 

DIVIDENDS 

A  dividend  in  specie  of  Ordinary  Shares  in  Probiotix  Health  Plc  was 
declared  on  25  March  2022.  The  value  of  the  dividend  was 
£10,257,999.99. 

The legal title to the Dividend Shares was held by Global Prime Partners 
Ltd acting as nominee on behalf of each of the Qualifying Shareholders 
(“Nominee”)  and  an  'omnibus'  share  certificate  in  respect  of  the 
Dividend Shares was issued and held by the Nominee. The Nominee 
held the Dividend Shares on trust for each of the Qualifying Shareholders 
for a minimum period of 9 months following admission to trading on 
AQSE  of  the  issued  share  capital  of  ProBiotix  Health  Plc  (“Lock-up 
Period”). The Lock-up Period was intended to contribute to the creation 
of an orderly market in ProBiotix Health Plcs shares for a period after 
admission to trading. 

The shares were released to the Qualifying shareholders in January 2023. 

FUTURE DEVELOPMENTS 

The  Chairman’s  and  Chief  Executive  Statement  on  pages  3-8  gives 
information on the future outlook of the Group. 

Corporate Governance 

Executive Management: 

The Group’s current executive team comprises: 

S O’Hara           Executive Director and CEO; with overall responsibility for 

all Group activities. 

Dr S Kolyda      Executive Director –  Research and Development Director 

Corporate Responsibility 

The  Board  takes  regular  account  of  the  significance  of  social, 
environmental  and  ethical  matters  affecting  the  Group  wherever  it 
operates. It has developed a specific set of policies on corporate social 
responsibility, which seek to protect the interests of all of its stakeholders 
through ethical and transparent actions and include an anti-corruption 
policy and code of conduct.  

Corporate Governance: 

The Group is committed to high standards of corporate governance and 
seeks to continually evaluate its policies, procedures and structures to 
ensure that they are fit for purpose. 

In  order  to  protect  the  interests  of  its  shareholders  and  other 
stakeholders the Board has chosen to adopt the Quoted Companies 
Alliance  (QCA)  Corporate  Governance  Code  for  Small  and  mid-size 
Quoted  Companies  (the “QCA  Code”),  and  the  Directors  are  always 
prepared, where practicable, to enter into dialogue with all such parties 
to promote a mutual understanding of objectives. 

By complying with this code the Company ensured compliance with 
the  new  AIM  Rules  regarding  Corporate  Governance  introduced 
September 2018. 

Full details of the Company's policy on Corporate Governance can be 
found on the website under: 

https://www.optibiotix-ir.com/content/investors/corporate-governance 

Composition of the Board of Directors 

The Board of Directors is currently comprised of the Chairman, Chief 
Executive Officer, the Research and development Director and the three 
Non-Executive Directors.  

11

OptiBiotix Health Plc 

 
Strategic Report (continued)

Role of the Board: 

Employees 

The role of the Board is to agree the Group’s long-term strategy and 
direction and to monitor achievement of its business objectives. The 
Board meets several times per annum, either by teleconference or in 
person. Furthermore, it holds additional meetings as are necessary to 
transact ongoing business. 

Board Committees: 

Remuneration Committee 

The  Remuneration  Committee  is  made  up  of  Chris  Brinsmead,  as 
Chairman  with  Neil  Davidson  and  Sean  Christie  and  has  access  to 
external expertise should that be required. This committee is responsible 
for the scale and structure of the remuneration of the Chief Executive, 
the  Executive  Directors  and  reports  to  the  Chief  Executive.  The 
recommendations of the committee must be approved by the Board 
of  Directors.  No  director  or  manager  shall  be  involved  in  decisions 
relating to his/her own remuneration. 

AIM Rules Compliance Committee 

The AIM Rules Compliance Committee is chaired by Neil Davidson. This 
committee  is  charged  with  ensuring  that  the  Group  has  sufficient 
procedures, resources and controls in place to ensure compliance with 
the AIM rules for companies. Among other things, the committee shall 
ensure  that  an  Executive  Director  is  at  all  times  able  to  respond  to 
requests  for  information  from  the  Nominated  Adviser  and  that  all 
Directors and employees are aware of their obligations with regards to 
the disclosure of any trading in the Group’s shares. 

Audit Committee 

The Audit Committee, is chaired by Sean Christie with Neil Davidson and 
Chris Brinsmead. This committee is required to monitor the integrity of 
the financial statements of the Group, including the interim and annual 
reports. The committee also reviews financial returns to regulators and 
any  financial  information  contained  in  announcements  of  a  price 
sensitive  nature.  The  committee  shall  also  consider  and  make 
recommendations  to  the  Board  regarding  resolutions  to  be  put  to 
shareholders for approval at the Annual General Meeting, with respect 
to the appointment or re-appointment of the Group’s external auditors. 
The  Audit  Committee,  together  with  the  external  auditors,  are 
responsible for determining the scope of the annual audit. 

Nomination Committee 

The Company does not currently have a nomination committee as the 
Board does not consider it appropriate to establish such a committee 
at this stage of the Company's development. Decisions which would 
usually be taken by the nomination committee will be taken by the 
Board as a whole. 

The Group engages its employees in all aspects of the business and 
seeks  to  remunerate  them  fairly.  The  Group  gives  full  and  fair 
consideration to applications for employment regardless of age, gender, 
colour,  ethnicity,  disability,  nationality,  religious  beliefs  or  sexual 
orientation. The Board takes employees’ interest into account when 
making decisions. Any suggestions from employees aimed at improving 
the Group’s performance are welcomed. 

Suppliers and Contractors 

The Group recognises that the goodwill of its contractors, consultants 
and suppliers is crucial to the success of its business, and seeks to build 
and  maintain  this  goodwill  through  fair  and  transparent  business 
practices. The Group aims to settle genuine liabilities in accordance with 
contractual obligations. 

Health and Safety 

The Board recognises that it has a responsibility to provide strategic 
leadership  and  direction  in  the  development  and  maintenance  of 
the  Group’s  health  and  safety  strategy,  in  order  to  protect  all  of 
its stakeholders. 

Section 172 Statement 

Under s172 of the Companies Act 2006 the Directors have a duty to act 
in good faith in a way that is most likely to promote the success of the 
Company for the benefit of its members as a whole, having regard to 
the likely consequences of decisions for the long term, the interests of 
the Company’s employees, the need to foster relationships with other 
key stakeholders, the impact on the community and the environment, 
maintaining a reputation for high standards of business conduct, and 
the need to act fairly as between members of the Company. 

Key decisions made by the Board during 2022 were related primarily to 

•

•

•

the  achievement  in  January  2022  of  British  Retail  Consortium 
accreditation, confirming our compliance with the Global Food 
Safety Initiative (‘GFSI’) benchmark. 

our  entry  into  the  sports  nutrition  market  with  the  launch  of 
LeanBiome®, a patented blend of dietary and prebiotic fibres and 
a  trace  mineral,  developed  to  support  athletes  increase  lean 
muscle mass and to improve metabolism, gut health and satiety 

admission of ProBiotix Health Plc to the AQSE Growth Market on 
31 March 2022, raising £2.5m for the further development of our 
former Probiotic subsidiary through a placing and subscription of 
new  shares,  while  giving  our  own  shareholders  a  dividend  in 
specie  of  0.554673  ProBiotix  share  for  every  OptiBiotix  Health 
share held. 

Annual Report and Accounts 2022 12

Social, Community and Human Rights 
Issues 

As an investment company with no employees the Company has no 
direct  social  or  community  responsibilities  or 
impact  on  the 
environment. The Company, however, takes into account the impact of 
environmental,  social  and  governance  factors  when  selecting  and 
managing its investments within the context of its obligation to manage 
investments in the financial interests of its shareholders. 

ON BEHALF OF THE BOARD 

S P O’Hara 
23 June 2023

Strategic Report (continued)

•

•

significant progress by one of our US partners in the commercial 
scale production of SweetBiotix®, with final product tested and 
accepted and now awaiting further structural analysis and formal 
taste  testing  to  determine  the  regulatory  pathway  before 
progressing to a launch ; and 

Significant scientific and commercial progress in the development 
of  our  microbiome  modulators:  a  range  of  second-generation 
products which selectively enhance the growth rate of specific 
types of bacteria and create the potential for targeted treatment 
of a range of human diseases. 

Employee engagement 

As a very small company in terms of staff, Board members have multiple 
points  of  contact  with  staff;  through  Board  meeting  feedback, 
participation in regular management meetings involving all staff, and 
ad hoc interactions in relation to specific matters. These forums provide 
staff with an opportunity to give their views which can then be taken 
into account in making decisions likely to affect their interests. Specific 
matters of concern to them as employees are dealt with in management 
meetings  and  by  email.  Corporate  developments  and  Company 
performance are discussed in regular management meetings. All staff 
are eligible for the Group’s share option scheme and this encourages 
involvement in the Company’s performance. 

Stakeholder Engagement 

The Group has a small number of major suppliers and distributors that 
support its delivery of strategy and corporate goals. The selection of, 
relationships with, and execution of, contracted work by these parties 
is considered regularly by the Executive Directors and at each Board 
meeting by all Directors. 

Shareholder Engagement 

The Company, through its corporate broker, Peterhouse Capital Limited, 
has  regular  contact  with  its  institutional  shareholders.  The  Board 
supports the principle that the Annual General Meeting be used to 
communicate  with  private  shareholders  and  encourages  them  to 
participate. The Annual General Meeting is attended by Directors. 

Greenhouse Gas Emissions 

The Company has no physical assets (other than a small amount of stock 
held  by  third  parties),  operations  or  premises.  Consequently,  it 
consumed less than 40,000 kWh of energy during the year so a detailed 
report on greenhouse gas emissions is not presented. 

13

OptiBiotix Health Plc 

 
Directors’ Report 
For the year ended 31 December 2022

The Directors present their report and the audited financial statements 
of the group for the year to 31 December 2022. 

PRINCIPAL ACTIVITY 

The principal activity of the group is that of identifying and developing 
microbial  strains,  compounds  and  formulations  for  use  in  food 
ingredients, supplements and active compounds that can impact on 
human physiology, deriving potential health benefits.  

DIRECTORS 

The directors who served the company during the year and up to the 
date of this report were as follows: 

Executive Directors 

S P O’Hara 
S Kolyda 

Non-executive Directors 

R Davidson 
M Christie 
C Brinsmead 
S Hammond 

Directors’ Remuneration 

The directors are entitled to receive relevant fees, as detailed in the 
directors’ remuneration in Note 4. 

Directors and their interests 

The directors of the Company held the following beneficial interests in 
the shares and share options of Optibiotix at the date of this report: 

Issued Share Capital

Share Warrants

Share Options 

Ordinary
shares of
£0.02 each

10,212,986
503,000
150,000
–
–
–
50,000

Percentage
Held 

Ordinary
shares of 
£0.02 each

Warrant
exercise
price

Ordinary
shares of 
£0.02 each

Option 
exercise 
price 

11.20%
0.55%
0.16%
–
–
–
0.05%

–
–
–
–
–
–
–

–
–
–
–
–
–
–

6,099,135
192,500
50,000
82,500
358,722
50,000
50,000

£0.08 
£0.02 
£0.02 
£0.02 
£0.20 
£0.02 
£0.02 

S P O’Hara
R Davidson
M Christie
S Kolyda
S Kolyda
C Brinsmead
S Hammond

The share options held by S P O’Hara were granted on 17 September 2016 and are exercisable at £0.08 at any time up 16 September 2024, subject 
to vesting conditions. 

The share options held by R Davidson were granted on 07 January 2022 and are exercisable at £0.02 at any time up 6 January 2032, subject to 
vesting conditions. On the same day R Davison surrendered 385,000 options at £0.73 and was granted options at £0.02. 

The share options held by M Christie were granted on 07 January 2022 and are exercisable at £0.02 at any time up 6 January 2032 , subject to 
vesting conditions. On the same day M Christie surrendered 50,000 options at £0.95 and was granted options at £0.02. 

The 358,772 share options held by S Kolyda were granted on 10 March 2015 and are exercisable at £0.20 at any time up 10 March 2025, subject to 
vesting conditions. 

The share options held by S Kolyda were granted on 07 January 2022 and are exercisable at £0.02 at any time up 6 January 2032, subject to vesting 
conditions. On the same day S Kolyda surrendered 82,500 options at £0.73 and was granted options at £0.02. 

The share options held by C Brinsmead were granted on 07 January 2022 and are exercisable at £0.02 at any time up 6 January 2032 , subject to 
vesting conditions. 

The share options held by S Hammond were granted on 07 January 2022 and are exercisable at £0.02 at any time up 6 January 2032 , subject to 
vesting conditions.

Annual Report and Accounts 2022 14

Directors’ Report (continued)

SUBSTANTIAL SHAREHOLDINGS 

Substantial shareholdings include directors as at 20 June 2023 were 
as follows: 

Stephen O’Hara
Finance Yorkshire Seedcorn LP

% of shares issued 

11.19 
10.36 

The share price per share at 31/12/2022 was £0.13 (31/12/2021: £0.46) 

have had regard to cash generation and preservation options including 
further cost mitigation, further sale of the Group's investment assets and 
share  issues  where  market  conditions  allow.  Through  one  or  a 
combination of these measures, the Board are satisfied that the Group 
can continue as a going concern in base case and downside scenarios. 

After making enquiries, the directors have a reasonable expectation that 
the Group has adequate resources to continue in operational existence 
for the foreseeable future. Accordingly, they continue to adopt a going 
concern basis in preparing the annual report and financial statements. 

FINANCIAL INSTRUMENTS 

The  Group’s  exposure  to  financial  risk  is  set  out  in  note  23  to  the 
financial statements. 

STATEMENT OF DIRECTORS’ 
RESPONSIBILITIES 

RESEARCH AND DEVELOPMENT 

The  Chairman’s  and  Chief  Executive’s  Report  on  pages  3-8  gives 
information on the Group’s research and development activities. 

DIRECTORS INDEMNITY INSURANCE 

The  Group  hold  a  Directors  and  Officers  policy  managed  by  CFC 
Underwriting Limited on behalf of Lloyds Syndicates with a limit of 
liability in the aggregate of £1,000,000. 

EVENTS AFTER THE REPORTING 
PERIOD 

Refer to Note 25 to the financial statements for further details. 

PUBLICATION OF ACCOUNTS ON 
GROUP WEBSITE 

Financial  statements  are  published  on  the  Group’s  website.  The 
maintenance and integrity of the website is the responsibility of the 
Directors. The  Directors’  responsibilities  also  extend  to  the  financial 
statements contained therein. 

GOING CONCERN 

The financial statements have been prepared on the assumption that 
the Group is a going concern. When assessing the foreseeable future, 
the Directors have looked at the budget for the next 12 months from 
the  date  of  this  report,  the  cash  at  bank  available  as  at  the  date  of 
approval of this report and are satisfied that the Group should be able 
to cover its forecast maintenance cost, other administrative expenses, 
as well as its ongoing research and development expenditure. 

As part of the Group going concern assessment the Directors have also 
reviewed a range of scenarios including those reflecting conditions less 
favourable than the base case scenario. In such scenarios the Directors 

15
15 OptiBiotix Health Plc 
OptiBiotix Health Plc 

The Directors are responsible for preparing the Directors’ Report and the 
financial statements in accordance with applicable laws and regulations. 

Company law requires the directors to prepare financial statements for 
each financial period. Under that law the directors have, as required by 
the AIM Rules for Companies of the London Stock Exchange, elected to 
in  accordance  with  UK  adopted 
prepare  financial  statements 
international  accounting  standards  (IFRS).  Under  company  law  the 
Directors must not approve the financial statements unless they are 
satisfied that they give a true and fair view of the state of affairs of the 
Group and of the profit or loss of the Group for that period. In preparing 
these financial statements, the Directors are required to: 

•

•

•

•

suitable  accounting  policies  and 

select 
them consistently. 

then  apply 

make judgements and estimates that are reasonable and prudent. 

state  whether  the  Group  and  parent  company  financial 
statements have been prepared in accordance with IFRS subject 
to any material departures disclosed and explained in the financial 
statements; and 

prepare  the  financial  statements  on  the  going  concern  basis, 
unless  it  is  inappropriate  to  presume  that  the  Company  will 
continue in business. 

The Directors confirm that the financial statements comply with the 
above requirements. 

The Directors are responsible for keeping adequate accounting records 
that are sufficient to show and explain the Group’s transactions and 
disclose with reasonable accuracy at any time the financial position of 
the Company and enable them to ensure that the financial statements 
comply with the Companies Act 2006. They are also responsible for 
safeguarding the assets of the Group and hence for taking reasonable 
steps for the prevention and detection of fraud and other irregularities. 

 
 
Directors’ Report (continued)

STATEMENT AS TO DISCLOSURE OF 
INFORMATION TO AUDITORS 

So far as the Directors are aware, there is no relevant audit information 
(as defined by Section 418 of the Companies Act 2006) of which the 
Group’s auditor is unaware, and each Director has taken all the steps 
that he ought to have taken as a Director in order to make himself aware 
of  any  relevant  audit  information  and  to  establish  that  the  Group’s 
auditor is aware of the information. 

AUDITOR 

Jeffreys Henry LLP has indicated that it will not seek re-appointment as 
the Company’s auditor at the Annual General Meeting as, following a 
business reorganisation, the firm will provide audit services to clients 
from another company in the group, Gravita Audit Limited. A resolution 
to  appoint  Gravita  Audit  Limited  as  the  Company’s  auditor  will  be 
proposed at the Annual General Meeting. 

STRATEGIC REPORT 

In accordance with section 414C(11) of the Companies Act 2006 the 
Group  chooses  to  report  the  future  outlook  and  the  risks  and 
uncertainties faced by the Group in the Strategic Report on page 9. 

ON BEHALF OF THE BOARD 
S P O’Hara 
23 June 2023

Annual Report and Accounts 2022 16

Independent Auditor’s Report to the Members of 
OptiBiotix Health Plc 
For the year ended 31 December 2021

Opinion 

We have audited the financial statements of Optibiotix Health Plc (the 
‘company’) and its subsidiaries (together the ‘group’) for the year ended 
31  December  2022  which  comprise  the  consolidated  statement  of 
comprehensive income, consolidated statement of financial position, 
consolidated statement of changes in equity, consolidated statement 
of  cash  flows,  company  statement  of  financial  position,  company 
statement of changes in equity, company statement of cash flows and 
notes to the financial statements, including a summary of significant 
accounting policies. The financial reporting framework that has been 
applied  in  the  preparation  of  the  group  and  company  financial 
statements is applicable law and UK-adopted International Accounting 
Standards (IFRS) as applied in accordance with the provision of the 
Companies Act 2006. 

In our opinion: 

•

•

•

•

the financial statements give a true and fair view of the state of 
the group’s and of the company’s affairs as at 31 December 2022 
and of the group’s profit for the year then ended; 

the  group  financial  statements  have  been  properly  prepared 
in  accordance  with  UK-adopted 
International  Accounting 
Standards (IFRS); 

the company financial statements have been properly prepared 
in  accordance  with  UK-adopted 
International  Accounting 
Standards (IFRS); and 

the financial statements have been prepared in accordance with 
the requirements of the Companies Act 2006. 

Basis for opinion 
We conducted our audit in accordance with International Standards on 
Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under 
those standards are further described in the Auditor’s responsibilities for 
the  audit  of  the  financial  statements  section  of  our  report.  We  are 
independent  of  the  company 
in  accordance  with  the  ethical 
requirements that are relevant to our audit of the financial statements in 
the UK, including the FRC’s Ethical Standard as applied to listed entities, 
and we have fulfilled our other ethical responsibilities in accordance with 
these  requirements.  We  believe  that  the  audit  evidence  we  have 
obtained is sufficient and appropriate to provide a basis for our opinion. 

Conclusions relating to going concern 
In  auditing  the  financial  statements,  we  have  concluded  that  the 
director's  use  of  the  going  concern  basis  of  accounting  in  the 
preparation of the financial statements is appropriate. Our evaluation of 
the directors’ assessment of the entity’s ability to continue to adopt the 
going concern basis of accounting included reviews of base case and 
downside cash flow scenarios and assessment of the ability of the group 
to realise its investment assets where needed to support the group’s 
cash position. 

17

OptiBiotix Health Plc 

Based on the work we have performed, we have not identified any 
material uncertainties relating to events or conditions that, individually 
or  collectively,  may  cast  significant  doubt  on  the  group's  ability  to 
continue as a going concern for a period of at least twelve months from 
when the financial statements are authorised for issue. 

Our responsibilities and the responsibilities of the directors with respect 
to going concern are described in the relevant sections of this report. 

Our approach to the audit 
As part of designing our audit, we determined materiality and assessed 
the  risks  of  material  misstatement  in  the  financial  statements.  In 
particular, we looked at where the directors made subjective judgments, 
for example in respect of significant accounting estimates that involved 
making assumptions and considering future events that are inherently 
uncertain.  As  in  all  of  our  audits  we  also  addressed  the  risk  of 
management override of internal controls, including evaluating whether 
there was evidence of bias by the directors that represented a risk of 
material misstatement due to fraud. 

How we tailored the audit scope 
We tailored the scope of our audit to ensure that we performed enough 
work to be able to give an opinion on the financial statements as a whole, 
taking into account the structure of the Group and the Company, the 
accounting processes and controls, and the industry in which they operate. 

The Group financial statements consolidate the results and balance of 
Optibiotix  Health  plc,  Optibiotix  Limited,  The  Healthy  Weight  Loss 
Company Limited, Optibiotix Health India Private Limited and, up to date 
when control was lost, the group headed by Probiotix Health Plc. 

We performed full scope audits of the financial information of Optibiotix 
Health plc, Optibiotix Limited, Probiotix Health Plc, Probiotix Limited and 
The Healthy Weight Loss Company Limited. We also performed targeted 
financial procedures on the financial information of Optibiotix Health 
India Private Limited. In total, the scope of audit work accounted for 
100% of the group’s revenue and 100% of the group’s profit. The group 
engagement team performed all audit procedures. 

Key audit matters 
Key audit matters are those matters that, in our professional judgment, 
were of most significance in our audit of the financial statements of the 
current period and include the most significant assessed risks of material 
misstatement (whether or not due to fraud) we identified, including 
those which had the greatest effect on: the overall audit strategy, the 
allocation of resources in the audit; and directing the efforts of the 
engagement team. These matters were addressed in the context of our 
audit of the financial statements as a whole, and in forming our opinion 
thereon, and we do not provide a separate opinion on these matters. 
This is not a complete list of all risks identified by our audit.

 
Independent Auditor’s Report to the Members  
of OptiBiotix Health Plc (continued)

Key audit matter

How our audit addressed the key audit matter

Loss of control of Probiotix Health Plc 

During the year, the directors assessed that the group lost control 
of Probiotix Health Plc as a result of a series of transactions which 
the board considered to form a single set of linked transactions. 
These transactions included the payment of a dividend in specie to 
shareholders of the company, the listing on AQSE Growth Market of 
Probiotix Health Plc, the automatic conversion of Probiotix Health 
Plc’s convertible loan notes upon admission to trading and the 
issue of new shares in Probiotix Heath plc. The result of these linked 
transactions was that the group’s interest in Probiotix Health Plc 
and Probiotix Limited fell from 100% to 44%. 

The Board determined that the date of loss of control was the date 
of Probiotix Health Plc’s admission to AQSE Growth, 31 March 2022. 

As a result, the result of Probiotix Health Plc was consolidated up to 
31 March 2022 at which time the group was deemed to lose 
control and therefore all assets and liabilities of Probiotix Health 
Plc were derecognised from the consolidated statement of 
financial position. 

The group reported a gain on disposal of Probiotix Health Plc as a 
result of the recognition of the dividend in specie at fair value and a 
remeasurement of the remaining interest at fair value. 
Management assessed that the facts and circumstances after the 
series of linked transactions resulting in the group having 
significant influence but not control over Probiotix Health Plc. 
Therefore from the date of loss of control the group’s interest in 
Probiotix Health Plc has been recorded as an associate and has 
been equity accounted.

We obtained the underlying documentation governing the series of 
transactions resulting in the loss of control of Probiotix Health Plc, 
including the Probiotix Admission Document to AQSE Growth, the 
convertible loan note instrument, board minutes and resolutions in 
respect of the dividend in specie and listing, shareholder registers 
and other relevant documents. 

We challenged management’s assessment of the nature of the 
relationship between the group and Probiotix Health Plc after 
31 March 2022 and reviewed key documents such as the 
Relationship Agreement and board minutes of both groups and 
examined the consistency of management’s arguments with the 
wider evidence reviewed. We found the evidence to support the 
judgement that the group did not control Probiotix Health Plc after 
31 March 2022. 

We reviewed the technical basis for the accounting treatment of 
the loss of control including by reference to IFRIC 17 and IFRS 10 in 
relation to dividends in specie and the treatment of retained 
interests following a loss in control respectively. We found the 
technical basis for the treatment of the series of linked transactions 
to be reasonable. 

We obtained and examined the application of cut off as at 31 March 
2022 in respect of the deconsolidation of the Probiotix group from 
that date with no material exception. We examined whether all 
assets and liabilities attributable to Probiotix Health Plc and 
Probiotix Limited were removed from the consolidated financial 
statements and reviewed the group’s disclosures in respect of 
the transaction. 

We determined that this matter was a key audit matter due to the 
significance of the financial impact on the group financial 
statements and the multiple judgements applied by management 

Annual Report and Accounts 2022 18

 
Independent Auditor’s Report to the Members  
of OptiBiotix Health Plc (continued)

Our application of materiality 

The scope of our audit was influenced by our application of materiality. We set certain quantitative thresholds for materiality. These, together with 
qualitative considerations, helped us to determine the scope of our audit and the nature, timing and extent of our audit procedures on the individual 
financial statement line items and disclosures and in evaluating the effect of misstatements, both individually and in aggregate on the financial 
statements as a whole. 

Based on our professional judgment, we determined materiality for the financial statements as a whole as follows: 

Group financial statements

Company financial statements

Overall materiality 

£92,000 (2021: £202,000)

£90,000 (2021: £178,000)

How we determined it

5% of adjusted profit 

1% of gross assets, capped at group materiality 

(2021: 1% gross assets)

(2021: 1% gross assets)

Rationale for  
benchmark applied 

The  group  reported  an  individually  significant 
gain on the loss of control of Probiotix Health Plc 
and an individually significant loss on revaluation 
of  its  interest  in  Skinbiotheraputics  plc.  These 
gains and losses were adjusted for the purposes 
of calculating materiality so as not to calculate an 
unduly  high  materiality  by  reference  to  the 
group’s trading operation.

We believe that gross assets is a primary measure 
the 
used  by 
performance  of  the  company.  Materiality  was 
restricted to group materiality.

in  assessing 

shareholders 

We agreed with the Audit Committee that we would report to them 
misstatements identified during our audit above £5,000 for the group 
(2021: £10,100) and £5,000 for the company (2021: £8,900) as well as 
misstatements  below  those  amounts  that,  in  our  view,  warranted 
reporting for qualitative reasons. 

Other information 

The  directors  are  responsible  for  the  other  information.  The  other 
information comprises the information included in the annual report, 
other than the financial statements and our auditor’s report thereon. 
Our  opinion  on  the  financial  statements  does  not  cover  the  other 
information and, except to the extent otherwise explicitly stated in our 
report, we do not express any form of assurance conclusion thereon. 

In  connection  with  our  audit  of  the  financial  statements,  our 
responsibility is to read the other information and, in doing so, consider 
whether  the  other  information  is  materially  inconsistent  with  the 
financial  statements  or  our  knowledge  obtained  in  the  audit  or 
otherwise appears to be materially misstated. If we identify such material 
inconsistencies or apparent material misstatements, we are required to 
determine whether there is a material misstatement in the financial 
statements or a material misstatement of the other information. If, based 
on the work we have performed, we conclude that there is a material 

misstatement  of  this  other  information,  we  are  required  to  report 
that fact. 

We have nothing to report in this regard. 

Opinions on other matters prescribed by 
the Companies Act 2006 

In our opinion, based on the work undertaken in the course of the audit: 

•

•

the information given in the strategic report and the directors’ 
report for the financial year for which the financial statements are 
prepared is consistent with the financial statements; and 

the strategic report and the directors’ report have been prepared 
in accordance with applicable legal requirements. 

Matters on which we are required to 
report by exception 

In the light of the knowledge and understanding of the group and 
parent company and its environment obtained in the course of the 
audit, we have not identified material misstatements in the strategic 
report or the directors’ report. 

1919

OptiBiotix Health Plc 

 
We have nothing to report in respect of the following matters in relation 
to which the Companies Act 2006 requires us to report to you if, in 
our opinion: 

The extent to which the audit was 
considered capable of detecting 
irregularities including fraud 

•

•

•

•

adequate accounting records have not been kept by the parent 
company,  or  returns  adequate  for  our  audit  have  not  been 
received from branches not visited by us; or 

the parent company financial statements are not in agreement 
with the accounting records and returns; or 

certain disclosures of directors’ remuneration specified by law are 
not made; or 

we have not received all the information and explanations we 
require for our audit. 

Responsibilities of directors 

As explained more fully in the directors’ responsibilities statement set 
out on page 20, the directors are responsible for the preparation of the 
financial statements and for being satisfied that they give a true and fair 
view,  and  for  such  internal  control  as  the  directors  determine  is 
necessary to enable the preparation of financial statements that are free 
from material misstatement, whether due to fraud or error. 

In preparing the financial statements, the directors are responsible for 
assessing the group’s and company’s ability to continue as a going 
concern, disclosing, as applicable, matters related to going concern and 
using the going concern basis of accounting unless the directors either 
intend  to  liquidate  the  group  or  the  parent  company  or  to  cease 
operations, or have no realistic alternative but to do so. 

Auditor’s responsibilities for the audit of 
the financial statements 

Our objectives are to obtain reasonable assurance about whether the 
financial statements as a whole are free from material misstatement, 
whether  due  to  fraud  or  error,  and  to  issue  an  auditor’s  report  that 
includes our opinion. Reasonable assurance is a high level of assurance, 
but is not a guarantee that an audit conducted in accordance with ISAs 
(UK)  will  always  detect  a  material  misstatement  when  it  exists. 
Misstatements can arise from fraud or error and are considered material 
if, individually or in the aggregate, they could reasonably be expected 
to influence the economic decisions of users taken on the basis of these 
financial statements. 

Irregularities, including fraud, are instances of non-compliance with laws 
and regulations. We design procedures in line with our responsibilities, 
outlined  above,  to  detect  material  misstatements  in  respect  of 
irregularities, including fraud. The extent to which our procedures are 
capable of detecting irregularities, including fraud is detailed below. 

Our  approach  to  identifying  and  assessing  the  risks  of  material 
misstatement  in  respect  of  irregularities,  including  fraud  and  non-
compliance with laws and regulations, was as follows: 

•

•

•

•

the  senior  statutory  auditor  ensured  the  engagement  team 
collectively had the appropriate competence, capabilities and skills 
to  identify  or  recognise  non-compliance  with  applicable  laws 
and regulations; 

we focused on specific laws and regulations which we considered 
may have a direct material effect on the financial statements or 
the operations of the group and company. 

we  assessed  the  extent  of  compliance  with  the  laws  and 
regulations  identified  above  through  making  enquiries  of 
management and inspecting legal correspondence; and 

identified laws and regulations were communicated within the 
audit team regularly and the team remained alert to instances of 
non-compliance throughout the audit. 

We  assessed  the  susceptibility  of  the  group  and  company  financial 
including  obtaining  an 
statements  to  material  misstatement, 
understanding of how fraud might occur, by: 

•

•

making enquiries of management as to where they considered 
there  was  susceptibility  to  fraud,  their  knowledge  of  actual, 
suspected and alleged fraud; 

considering the internal controls in place to mitigate risks of fraud 
and non-compliance with laws and regulations. 

To address the risk of fraud through management bias and override of 
controls, we: 

•

•

•

•

performed  analytical  procedures  to  identify  any  unusual  or 
unexpected relationships; 

tested journal entries to identify unusual transactions; 

assessed  whether 
judgements  and  assumptions  made 
in  determining  the  accounting  estimates  were  indicative  of 
potential bias; 

investigated  the  rationale  behind  significant  or  unusual 
transactions. 

In response to the risk of irregularities and non-compliance with laws 
and regulations, we designed procedures which included, but were not 
limited to: 

•

agreeing financial statement disclosures to underlying supporting 
documentation; 

20
Annual Report and Accounts 2022 20

Independent Auditor’s Report to the Members  
of OptiBiotix Health Plc (continued)

•

•

•

reading 
with governance; 

the  minutes  of  meetings  of 

those  charged 

enquiring of management as to actual and potential litigation 
and claims; 

obtaining  confirmation  of  compliance  from  the  company’s 
legal advisors. 

There are inherent limitations in our audit procedures described above. 
The  more  removed  that  laws  and  regulations  are  from  financial 
transactions, the less likely it is that we would become aware of non-
compliance. Auditing standards also limit the audit procedures required 
to identify non-compliance with laws and regulations to enquiry of the 
directors and other management and the inspection of regulatory and 
legal correspondence, if any. 

Material misstatements that arise due to fraud can be harder to detect 
than  those  that  arise  from  error  as  they  may  involve  deliberate 
concealment or collusion. 

A further description of our responsibilities for the audit of the financial 
statements is located on the Financial Reporting Council’s website at: 
www.frc.org.uk/auditorsresponsibilities. This description forms part of 
our auditor’s report. 

Use of this report 

This report is made solely to the company’s members, as a body, in 
accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our 
audit  work  has  been  undertaken  so  that  we  might  state  to  the 
company’s members those matters we are required to state to them in 
an  auditor’s  report  and  for  no  other  purpose.  To  the  fullest  extent 
permitted by law, we do not accept or assume responsibility to anyone 
other than the company and the company’s members as a body, for our 
audit work, for this report, or for the opinions we have formed. 

Sachin Ramaiya 
(Senior Statutory Auditor) 
For and on behalf of  

Jeffreys Henry LLP, Statutory Auditor 

Finsgate 
5-7 Cranwood Street 
London  
EC1V 9EE 

23 June 2022

21

OptiBiotix Health Plc 

 
Consolidated Statement of Comprehensive Income 
For the year ended 31 December 2022

Revenue from contracts with customers
Cost of sales

Gross profit
Share based payments 
Depreciation and amortisation
Other administrative costs

Total administrative expenses

Operating loss
Finance cost
Finance income 

Share of loss from associate
(Loss)/Gain on investments
Profit on disposal of investments
Profit on disposal of subsidiary 
Provision against associate valuation

Profit/(Loss) before tax
Taxation

Total comprehensive income for the period 

Total comprehensive income attributable to: 
Owners of the company
Non-controlling interests

Earnings per share from continued operations 
Basic profit/(loss) per share 
Diluted profit/(loss) per share 

All activities relate to continuing operations 

The notes on pages 31 to 54 form part of these financial statements

Notes

Year ended
31 December 2022
£’000

Year ended  
31 December 2021 
£’000 

457
(213)

244
(11)
(224)
(2,498)

(2,733)

(2,489)
–
–

–
(83)
(8,620)
16
21,647
(8,030)

2,441
146

2,587

2.587
–

2,587

2.93p
2.78p

2,213 
(1,090) 

1,123 
(60) 
(288) 
(2,140) 

(2,488) 

(1,365) 
(48) 
– 

(48) 
– 
7,502 
88 
– 
– 

 6,177 
84 

6,261 

6,261 
– 

6,261 

7.15p 
6.55p 

6

5
5

11
11
11
11
11

7

8
8

Annual Report and Accounts 2022 22

Consolidated Statement of Financial Position 
As at 31 December 2022

ASSETS 
Non-current assets 
Intangibles
Investments
Investment in associate

CURRENT ASSETS 
Inventories
Trade and other receivables
Current tax asset
Cash and cash equivalents

TOTAL ASSETS

EQUITY 
Shareholders’ Equity 
Called up share capital
Share premium
Share based payment reserve
Merger relief reserve
Convertible debt – reserve
Retained Earnings

Non-controlling interest

Total Equity

LIABILITIES 
Current liabilities 
Trade and other payables

Non-current liabilities 
Deferred tax liability
Convertible loan notes 

TOTAL LIABILITIES

TOTAL EQUITY AND LIABILITIES

Notes

As at
31 December 2022
£’000

As at 
31 December 2021 
£’000 

9
11
11

12
13
7
14

15
16
16
16
16
16

16

17

18
19

1,540
5,022
3,129

9,691

178
521
106
1,052

1,857

11,548

1,824
2,958
939
1,500
–
3,684

10,905
–

10,905

278

278

365
–

365
643

11,548

2,641 
13,651 
– 

16,292 

102 
1,553 
191 
2,007 

3,853 

20,145 

1,759 
2,537 
928 
1,500 
93 
11,320 

18,137 
35 

18,172 

602 

602 

552 
819 

1,371 
1,973 

20,145 

These financial statements were approved and authorised for issue by the Board of Directors on 23 June 2023 and were signed on 
its behalf by: 
S P O’Hara 
Director 
Company Registration no. 05880755 
The notes on pages 31 to 54 form part of these financial statement
23

OptiBiotix Health Plc 

 
Consolidated Statement of Changes in Equity 
For the year ended 31 December 2022

                                                                                                                                        Share-                                                                 
                                                                                                                                         based     Convertible           Merger              Non-
                                                                  Called up         Retained              Share          Payment              Debt              Relief     Controlling
                                                              Share capital          Earnings         Premium           reserve          Reserve          Reserve           interest
                                                                        £’000              £’000              £’000              £’000              £’000              £’000              £’000

Balance at 31 December 2020                             1,759              5,059              2,537                868                  93              1,500                  35
Profit for the year                                                      –              6,261                    –                    –                    –                    –                    –
Share options and warrants                                        –                    –                    –                  60                    –                    –                    –

Balance at 31 December 2021                             1,759            11,320              2,537                928                  93              1,500                  35
Profit for the year                                                      –              2,587                    –                    –                    –                    –                    –
Dividends                                                                 –           (10,258)                   –                    –                    –                    –                    –
Transfer on loss of control                                          –                    –                    –                    –                 (93)                   –                    –
Transfer within reserves                                             –                  35                    –                    –                    –                    –                 (35)
Issue of shares during the year                                  65                    –                445                    –                    –                    –                    –
Fundraising commission                                             –                    –                 (24)                   –                    –                    –                    –
Share Options and warrants                                       –                    –                    –                  11                    –                    –                    –

Total 
equity 
£’000 

11,851 
6,261 
60 

18,172 
2,587 
(10,258) 
(93) 
– 
510 
(24) 
11 

Balance at 31 December 2022                             1,824              3,684              2,958                939                    –              1,500                    –

10,905 

The notes on pages 31 to 54 form part of these financial statements 

Annual Report and Accounts 2022 24

 
 
Consolidated Statement of Cash Flows 
For the year ended 31 December 2022

Notes

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

Opening Cash

Operating activities
Operating loss
Amortisation
Share based payments
Movement on inventory
Decrease/(increase) on receivables
(Decrease)/increase on payables
Tax received

Net Proceeds for operating activities

Investing activities
Additions to intangibles 
Cash disposed on loss of subsidiary
Proceeds on disposal of investments 

Net 

Financing activities
Net proceeds on Share issues

Net cash inflow from financing activities

Total movement

Cash and cash equivalents at end of period

1

The notes on pages 31 to 54 form part of these financial statements 

2,007

(2,489)
224
11
(76)
1,116
(19)
124

(1,109)

(168)
(188)
25

(331)

485

485

(955)

1,052

865 

(1,365) 
288 
60 
82 
(906) 
82 
194 

(1,565) 

(194) 
– 
2,901 

2,707 

– 

– 

1,142 

2,007 

25

OptiBiotix Health Plc 

 
 
 
 
 
Notes to the Consolidated Statement of Cash Flows 
For the year ended 31 December 2022

1. Cash and Cash Equivalents 

Cash and cash equivalents

The notes on pages 31 to 54 form part of these financial statements 

Year ended 
31 December
2022
£’000

Year ended   

31 December 
 2021 
£’000 

1,052

2,007 

Annual Report and Accounts 2022 26

Company Statement of Financial Position 
As at 31 December 2022

ASSETS 
Non-current assets 
Investments
Investment in associate 
Other receivables

CURRENT ASSETS 
Trade and other receivables
Cash and cash equivalents

TOTAL ASSETS

EQUITY 
Shareholders’ Equity 
Called up share capital
Share premium
Merger relief reserve
Share based payment reserve
Accumulated profit

Total Equity

LIABILITIES 
CURRENT LIABILITIES 
Trade and other payables

TOTAL LIABILITIES

TOTAL EQUITY AND LIABILITIES

As at
31 December 2022
£’000

As at 
31 December 2021 
£’000 

Notes

11
11
13

13
14

15
16
16
16
16

17

7,008
3,212
–

10,220

25
865

890

11,110

1,824
2,958
1,500
939
3,806

11,027

83

83

11,110

15,732 
– 
318 

16,050 

66 
1,705 

1,771 

17,821 

1,759 
2,537 
1,500 
928 
11,056 

17,780 

41 

41 

17,821 

The Company has elected to take the exemption under section 408 of the Companies Act 2006 not to present the Company 
income statement. 
The profit for the Company for the year was £3.008m (2021: £5.788m). 
These financial statements were approved and authorised for issue by the Board of Directors on 23 June 2023 and were signed on 
its behalf by: 
S P O’Hara 
Director 
Company Registration no. 05880755  

The notes on pages 31 to 54 form part of these financial statements 

27

OptiBiotix Health Plc 

 
 
Company Statement of Changes in Equity 
For the year ended 31 December 2022

Called up
Share
capital
£’000

Share
Premium
£’000

Merger Share-based 
Payment
reserve
£’000

Relief 
Reserve
£’000

Balance at 31 December 2020

1,759

2,537

1,500

Profit for the year

Share options and warrants

–

–

–

–

–

–

Balance at 31 December 2021

1,759

2,537

1,500

Profit for the year

Dividends

Share options and warrants

Fundraising Commission

Issue of shares during the year

Balance at 31 December 2022

–

–

–

–

65

1,824

–

–

–

(24)

445

–

–

–

–

2,958

1,500

The notes on pages 31 to 54 form part of these financial statements 

868

–

60

928

–

–

11

–

939

Retained
Earnings
£’000

5,268

5,788

–

Total 
equity 
£’000 

11,932 

5,788 

60 

11,056

17,780 

3,008

3,008 

(10,258)

(10,258) 

–

–

11 

(24) 

510 

3,806

11,027 

Annual Report and Accounts 2022 28

Company Statement of Cash Flows 
For the year ended 31 December 2022

Year ended 
31 December 2022
£’000

Year ended   

31 December 2021 
£’000 

Notes

Opening Cash

Operating activities
Operating loss
Share based payments
Decrease/(increase) on receivables
Impairment of investment in subsidiary
(Decrease)/increase on payables
Release of loan to subsidiary

Net Proceeds for operating activities

Investing activities
Net cash advances to subsidiary 
Proceeds on disposal of investments 

Net 

Financing activities
Net proceeds on Share issues

Net cash inflow from financing activities

Total movement

Cash and cash equivalents at end of period

1

The notes on pages 31 to 54 form part of these financial statements 

1.705

(1,482)
11
416
50
42
756

(207)

(1,143)
25

(1,118)

485

485

(840)

865

533 

(2,749) 
60 
24 
– 
(22) 
932 

(1,755) 

26 
2,901 

2,927 

– 

– 

1,172 

1,705 

29

OptiBiotix Health Plc 

 
 
 
 
Notes to the Company Statement of Cash Flows 
For the year ended 31 December 2022

1. Cash and Cash Equivalents 

Cash and cash equivalents

The notes on pages 31 to 54 form part of these financial statements 

As at 
31 December 2022
 £’000

865

As at 
31 December 2021 

£’000   

1,705 

Annual Report and Accounts 2022 30

Notes to the Financial Statements 
For the year ended 31 December 2021

1. General Information 

OptiBiotix Health plc is a Public Limited Company limited by shares, incorporated and domiciled in England and Wales. Details of 
the registered office, the officers and advisers to the Company are presented on the company information page at the start of this 
report. The Company's offices are at Innovation Centre, Innovation Way, Heslington, York, YO10 5DG. The Company is listed on the 
AIM market of the London Stock Exchange (ticker: OPTI). 

The principal activity is that of identifying and developing microbial strains, compounds, and formulations for use in food ingredients, 
supplements and active compounds that can impact on human physiology, deriving potential health benefits. 

These financial statements present the results and balances of the Company and its subsidiaries (together, the ‘Group’) for the year 
ended 31 December 2022. 

2. Accounting Policies 

Statement of compliance 

The consolidated and parent financial statements of Optibiotix Health Plc have been prepared in accordance with UK adopted 
international accounting standards (IFRSs), IFRIC interpretations and the Companies Act 2006 applicable to companies reporting 
under IFRS. 

Basis of preparation 

The financial statements have been prepared under the historical cost convention. The functional currency is GBP. 

The principal accounting policies are summarised below. They have all been applied consistently throughout the period under 
review. The results are rounded to the nearest thousand. 

Going concern 

The financial statements have been prepared on the assumption that the Group is a going concern. When assessing the foreseeable 
future, the Directors have looked at the budget for the next 12 months from the date of this report, the cash at bank available as 
at the date of approval of these financial statements and are satisfied that the group should be able to cover its forecast maintenance 
costs, other administrative expenses and its ongoing research and development expenditure. 

As part of the Group going concern assessment the Directors have also reviewed a range of scenarios including those reflecting 
conditions less favourable than the base case scenario. In such scenarios the Directors have had regard to cash generation and 
preservation options including further cost mitigation, further sale of the Group's investment assets and share issues where market 
conditions allow. Through one or a combination of these measures, the Board are satisfied that the Group can continue as a going 
concern in base case and downside scenarios. 

Management have considered its forecast of the group’s cash requirements reflecting contracted and anticipated future revenue 
and the resulting net cash outflows. Management have not seen a material disruption to the business as a result of the current 
political crises in Eastern Europe. Management will keep events under constant review, and remedial action will be taken if the 
situation demands it. 

After making enquiries, the Directors have a reasonable expectation that the Group has adequate resources to continue in 
operational existence for the foreseeable future. Accordingly, they continue to adopt a going concern basis in preparing the annual 
report and financial statements 

31

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

Standards, amendments and interpretations effective and adopted in 2022 

New Standards and interpretations The following IFRS or IFRIC interpretations which are effective for the first time in the Group’s 
accounting period to December 2022 have been considered by the Directors. Their adoption is not expected to, and will not, have 
any material impact on the disclosures or on the amounts reported in this financial information. 

Standards/interpretations Application 

Standard or
Interpretation

Title

IFRS 3
IAS 16
IFRS 9

IAS 1

amendments Business Combinations
amendments Provisions, Contingent Liabilities and Contingent Assets
amendments Annual Improvements to IFRS 
Standards 2018–2020 (fees in the 10 percent test for 
derecognition of financial liabilities).
amendments Presentation of Financial Statements

Effective for annual 
periods beginning 
on or after  

1 January 2022 
1 January 2022 

1 January 2022 
1 January 2022 

There are no other IFRSs or IFRIC interpretations that are not yet effective that would be expected to have a material impact on 
the Group. 

The Directors anticipate that the adoption of these standards and the interpretations in future period will have no material impact 
on the financial statements of the company. 

2.1 Basis of consolidation 

The consolidated financial statements incorporate the financial statements of the Company and entities controlled by the Company 
(its subsidiaries) made up to 31 December each year. The group controls an investee when it is exposed, or has rights, to variable 
returns from its involvement with the investee and has the ability to affect those returns through its power over the investee. 

The results of subsidiaries acquired or disposed of during the year are included in the consolidated statement of comprehensive 
income from the effective date of acquisition or up to the effective date of disposal, as appropriate. 

Where necessary, adjustments are made to the financial statements of subsidiaries to bring their accounting policies into line with 
those used by other members of the Group. 

All intra-group transactions, balances, income and expenses are eliminated on consolidation. 

Changes in the Group’s ownership interests in subsidiaries that do not result in the Group losing control over the subsidiaries are 
accounted for as equity transactions. The carrying amounts of the Group’s interests and the non-controlling interests are adjusted 
to reflect the changes in their relative interests in the subsidiaries. Any difference between the amount by which the non-controlling 
interests are adjusted and the fair value of the consideration paid or received is recognised directly in equity and attributed to owners 
of the Company. 

When the Group loses control of a subsidiary, the profit or loss on disposal is calculated as the difference between (i) the aggregate 
of the fair value of the consideration received and the fair value of any retained interest and (ii) the previous carrying amount of the 
assets (including goodwill), and liabilities of the subsidiary and any non-controlling interests. Where certain assets of the subsidiary 
are measured at revalued amounts or fair values and the related cumulative gain or loss has been recognised in other comprehensive 
income and accumulated in equity, the amounts previously recognised in other comprehensive income and accumulated in equity 
are accounted for as if the Company had directly disposed of the related assets (i.e. reclassified to profit or loss or transferred directly 
to retained earnings). 

Annual Report and Accounts 2021 32

 
Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

The fair value of any investment retained in the former subsidiary at the date when control is lost is regarded as the fair value on 
initial recognition for subsequent accounting under IFRS 9 “Financial Instruments: Recognition and Measurement” or, when applicable, 
the cost on initial recognition of an investment in an associate or a jointly controlled entity. 

Business combinations 

Acquisitions of businesses are accounted for using the acquisition method. The consideration transferred in a business combination 
is measured at fair value, which is calculated as the sum of the acquisition-date fair values of the assets transferred by the Group, 
liabilities incurred by the group to the former owners of the acquiree and the equity interests issued by the group in exchange for 
control of the acquiree. Acquisition-related costs are recognised in profit or loss as incurred. 

At the acquisition date, the identifiable assets acquired and the liabilities assumed are recognised at their fair value at the acquisition 
date, except that: 

–

–

–

deferred tax assets or liabilities and liabilities or assets related to employee benefit arrangements are recognised and measured 
in accordance with IAS 12 Income Taxes and IAS 19 Employee Benefits respectively; 

liabilities or equity instruments related to share-based payment transactions of the acquiree or the replacement of an 
acquiree's  share-based  payment  transactions  with  share-based  payment  transactions  of  the  group  are  measured  in 
accordance with IFRS 2 Share-based Payment at the acquisition date; and 

assets (or disposal groups) that are classified as held for sale in accordance with IFRS 5 Non-current Assets Held for Sale and 
Discontinued Operations are measured in accordance with that standard. 

Goodwill is measured as the excess of the sum of the consideration transferred, the amount of any non-controlling interests in the 
acquiree, and the fair value of the acquirer's previously held equity interest in the acquiree (if any) over the net of the acquisition-
date amounts of the identifiable assets acquired and the liabilities assumed. If, after assessment, the net of the acquisition-date 
amounts of the identifiable assets acquired and liabilities assumed exceeds the sum of the consideration transferred, the amount of 
any non-controlling interests in the acquiree and the fair value of the acquirer's previously held interest in the acquiree (if any), the 
excess is recognised immediately in profit or loss as a bargain purchase gain. 

2.2 Revenue recognition 

Revenue is measured at the fair value of sales of goods and services less returns and sales taxes. The Group has analysed its business 
activities and applied the five-step model prescribed by IFRS 15 to each material line of business, as outlined below: 

2.2.1 Sale of products  

The contract to provide a product is established when the customer places a purchase order. The performance obligation is to 
provide the product requested by an agreed date, and the transaction price is the value of the product as stated in our order 
acknowledgement. The performance obligation is typically met when the product is dispatched and so revenue is primarily 
recognised for each product when dispatching takes place. In some limited situations when the product is complete but the 
customer is unable to take delivery the performance obligation is met when the customer formally accepts transfer of risk and 
control even though the product has not been dispatched.  

2.2.2 License arrangements 

Revenue is recognised when the customer obtains control of the rights to use the IP. The performance obligations are considered 
to be distinct from any ongoing distribution arrangements which are treated in line with sales of products. 

33

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

2.2.3  Milestone payments 

Where the transaction price includes consideration that is contingent upon a future event or circumstance, the contingent 
amount is allocated entirely to that performance obligation if certain criteria are met. Revenue is recognised at the point of time 
of the performance obligation being satisfied. 

2.3 Investments in associates 

Associates are those entities in which the Group has significant influence, but not control or joint control over the financial and 
operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power 
of another entity. Investments in associates are accounted for under the equity method and are recognised initially at cost. The cost 
of the investment includes transaction costs. 

The consolidated financial statements include the Group’s share of profit or loss and other comprehensive income of equity-
accounted investees, after adjustments to align the accounting policies with those of the Group, from the date that significant 
influence commences until the date that significant influence ceases. 

When the Group’s share of losses exceeds its interest in an equity-accounted investee, the carrying amount of the investment, 
including any long-term interests that form part thereof, is reduced to zero, and the recognition of further losses is discontinued 
except to the extent that the Group has an obligation or has made payments on behalf of the investee. 

2.4 Investments at fair value 

Equity investments are held at fair value at the balance sheet date with any profit or loss for the year being taken to the Income 
statement. The value of listed investments being calculated at the closing price on the balance sheet date. 

2.5 Employee Benefits 

The Group operates a defined contribution pension scheme. Contributions payable by the Group’s pension scheme are charged to 
the income statement in the period in which they relate. 

2.6 Taxation 

Income tax expense represents the sum of the tax currently payable and deferred tax. 

(i) Current tax 

Current taxes are based on the results shown in the financial statements and are calculated according to local tax rules using tax 
rates enacted or substantially enacted by the statement of financial position date. 

Income tax is recognised in the income statement or in equity if it relates to items that are recognised in the same or a different 
period, directly in equity. 

Current tax assets and liabilities for the current and prior periods are measured at the amount expected to be recovered from or 
paid to the taxation authorities. 

(ii) Deferred tax 

Deferred tax is provided, using the liability method, on temporary differences at the statement of financial position date between 
the tax base of assets and liabilities and their carrying amounts for financial reporting purposes. 

Deferred tax liabilities are recognised for all taxable temporary differences. 

Annual Report and Accounts 2021 34

Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

Deferred tax assets are recognised for all deductible temporary differences, carry forward of unused tax assets and unused tax losses, 
to the extent that it is probable that taxable profit will  be available against which the deductible temporary differenced and the 
carrying forward or unused tax assets and unused tax losses can be utilised. 

The carrying amount of deferred tax assets is reviewed at each balance sheet date and reduced to the extent that it is no longer 
probable that sufficient taxable profit will be available to allow all or part of the deferred tax assets to be utilised. Conversely, previously 
unrecognised deferred tax assets are recognised to the extent that it is probable that sufficient taxable profit that sufficient taxable 
profit will be available to allow all or part of the deferred tax asset to be utilised. 

Deferred tax assets and liabilities are measured at the tax rates that are expected to apply to the year when the asset is realised or 
the liability is settled, based on the tax rates and tax laws that have been enacted or substantively enacted at the balance sheet date. 

2.7 Financial instruments 

Financial  assets  and  financial  liabilities  are  recognised  when  the  group  becomes  a  party  to  the  contractual  provisions  of 
the instrument. 

Loans and receivables are initially measured at fair value and are subsequently measured at amortised cost, plus accrued 
2.8
interest, and are reduced by appropriate provisions for estimated irrecoverable amounts. Such provisions are recognised in the 
statement of income. 

Equity investments comprise investments which do have a fixed maturity and are classified as non current assets if they are 

2.9
intended to be held for the medium to long term. They are measured at fair value through profit or loss. 

2.10 Trade receivables are initially measured at fair value and are subsequently measured at amortised cost less appropriate 
provisions for credit losses. Such provisions are recognised in the income statement. 

2.11 Cash and cash equivalents comprise cash in hand and demand deposits and other short-term highly liquid investments 
with maturities of three months or less at inception that are readily convertible to a known amount of cash and are subject to an 
insignificant risk of changes in value. 

2.12 Trade payables are not interest-bearing and are initially valued at their fair value and are subsequently measured at amortised 
cost. 

2.13

Equity instruments are recorded at fair value, being the proceeds received, net of direct issue costs. 

Share Capital – Ordinary shares are classified as equity. Incremental costs directly attributable to the issue of new shares or 

2.14
options are shown in equity as a deduction, net of taxation, from the proceeds. 

Financial instruments require classification of fair value as determined by reference to the source of inputs used to derive 

2.15
the fair value. This classification uses the following three-level hierarchy: 

Level 1 – quoted prices (unadjusted) in active markets for identical assets or liabilities; 

Level 2 — inputs other than quoted prices included within level 1 that are observable for the asset or liability, either directly (i.e., as 
prices) or indirectly (i.e., derived from prices); 

Level 3 — inputs for the asset or liability that are not based on observable market data (unobservable inputs). 

2.16

Inventory 

Inventories are stated at the lower of cost and net realisable value. Cost is determined using the first-in, first-out (FIFO) method. Net 
realisable value is the estimated selling price in the ordinary course of business, less applicable variable selling expenses. 

35

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

2.17

Impairment of non-financial assets 

At each statement of financial position date, the Group reviews the carrying amounts of its investments to determine whether there 
is any indication that those assets have suffered an impairment loss. If any such indication exists, the recoverable amount of the 
asset is estimated in order to determine the extent of the impairment loss (if any). Where the asset does not generate cash flows 
that are independent from other assets, the group estimates the recoverable amount of the cash-generating unit to which the asset 
belongs. An intangible asset with an indefinite useful life is tested for impairment annually and whenever there is an indication that 
the asset may be impaired. 

Recoverable amount is the higher of fair value less costs to sell and value in use. In assessing value in use, the estimated future cash 
flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value 
of money and the risks specific to the asset for which the estimates of future cash flows have not been adjusted. 

If the recoverable amount of an asset (or cash-generating unit) is estimated to be less than its carrying amount, the carrying amount 
of the asset (cash-generating unit) is reduced to its recoverable amount. An impairment loss is recognised as an expense immediately, 
unless the relevant asset is carried at a re-valued amount, in which case the impairment loss is treated as a revaluation decrease. 

Where an impairment loss subsequently reverses, the carrying amount of the asset (cash-generating unit) is increased to the revised 
estimate of its recoverable amount, but so that the increased carrying amount does not exceed the carrying amount that would 
have been determined had no impairment loss been recognised for the asset (cash-generating unit) in prior years. A reversal of an 
impairment loss is recognised as income immediately, unless the relevant asset is carried at a revalued amount, in which case the 
reversal of the impairment loss is treated as a revaluation increase. 

2.18

Capital management 

Capital is made up of stated capital, premium, other reserves and retained earnings. The objective of the Group’s capital management 
is to ensure that it maintains strong credit ratings and capital ratios. This will ensure that the business is correctly supported and 
shareholder value is maximised. 

The Group manages its capital structure through adjustments that are dependent on economic conditions. In order to maintain or 
adjust the capital structure, the Company may choose to change or amend dividend payments to shareholders or issue new share 
capital to shareholders. There were no changes to the objectives, policies or processes during the period ended 31 December 2022. 

2.19

Convertible Loans 

Compound financial instruments issued by the Group comprise convertible notes that can be converted to share capital at the 
option of the holder, and the number of shares to be issued does not vary with changes in their fair value. 

The liability component of a compound financial instrument is recognised initially at the fair value of a similar liability that does not 
have an equity conversion option. The equity component is recognised initially at the difference between the fair value of the 
compound financial instrument as a whole and the fair value of the liability component. Any directly attributable transaction costs 
are allocated to the liability and equity components in proportion to their initial carrying amount. 

2.20

Convertible debt reserve 

The convertible debt reserve is the equity component of the convertible loan notes that have been issued. 

2.21

Share-based compensation 

The fair value of the employee and suppliers services received in exchange for the grant of the options is recognised as an expense. 
The total amount to be expensed over the vesting year is determined by reference to the fair value of the options granted, excluding 
the impact of any non-market vesting conditions (for example, profitability and sales growth targets). Non-market vesting conditions 
are included in assumptions about the number of options that are expected to vest. At each statement of financial position date, 

Annual Report and Accounts 2021 36

Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

the entity revises its estimates of the number of options that are expected to vest. It recognises the impact of the revision to original 
estimates, if any, in the income statement, with a corresponding adjustment to equity. 

The proceeds received net of any directly attributable transaction costs are credited to share capital (nominal value) and share 
premium when the options are exercised. 

The fair value of share-based payments recognised in the income statement is measured by use of the Black Scholes model, which 
takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used in the model 
is adjusted; based on management’s best estimate, for the effects of non-transferability, exercise restrictions and behavioural 
considerations. The share price volatility percentage factor used in the calculation is based on management’s best estimate of future 
share price behaviour and is selected based on past experience, future expectations and benchmarked against peer companies in 
the industry. 

2.22

Property, plant and equipment 

Property, plant and equipment are stated at historical cost less subsequent accumulated depreciation and accumulated impairment 
losses, if any. Historical cost includes expenditure that is directly attributable to the acquisition of the items. 

Subsequent costs are included in the asset’s carrying amount or recognised as a separate asset, as appropriate, only when it is 
probable that future economic benefits associated with the item will flow to the Group and the cost of the item can be measured 
reliably. All other repairs and maintenance are charged to profit or loss during the financial period in which they are incurred. 

Depreciation on property, plant and equipment is calculated using the straight-line method to write off their cost over their estimated 
useful lives at the following annual rates: 

Computer equipment

30% 

Useful lives and depreciation method are reviewed and adjusted if appropriate, at the end of each reporting period. 

An item of property, plant and equipment is derecognised upon disposal or when no future economic benefits are expected to 
arise from the continued use of the asset. Any gain or loss arising on the disposal or retirement of an item of property, plant and 
equipment is determined as the difference between the sales proceeds and the carrying amount of the relevant asset and is 
recognised in profit or loss in the year in which the asset is derecognised.  

2.23

Intangibles – Patents 

Separately acquired patents are shown at historical cost. Patents have a finite useful life and are carried at cost less accumulated 
amortisation. Amortisation is calculated using the straight line method to allocate the cost of the patents over their estimated useful 
life of twenty years once the patents have been granted. 

2.24

Research and Development 

Research expenditure is written off to the statement of comprehensive income in the year in which it is incurred. Development 
expenditure is written off in the same way unless the Directors are satisfied as to the technical, commercial and financial viability of 
individual projects. In this situation, the expenditure is deferred and amortised over the 10 years during which the Company is 
expected to benefit. 

2.25

Merger relief reserve 

The merger relief reserve arises from the 100% acquisition of OptiBiotix Limited whereby the excess of the fair value of the issued 
ordinary share capital issued over the nominal value of these shares is transferred to this reserve in accordance with section 612 of 
the Companies Act 2006. 

37

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

2.26

Critical accounting judgments and key sources of estimation uncertainty 

The preparation of the financial statements requires management to make estimates and assumptions concerning the future that 
affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the dates of the financial 
statements and the reported amounts of revenues and expenses during the reporting periods. 

The resulting accounting estimates will, by definition, differ from the related actual results. 

•

•

•

•

Share based payments 
The fair value of share based payments recognised in the income statement is measured by use of the Black Scholes model, 
which takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used 
in the model is adjusted; based on management’s best estimate, for the effects of non-transferability, exercise restrictions 
and behavioural considerations. The share price volatility percentage factor used in the calculation is based on management’s 
best estimate of future share price behaviour and is selected based on past experience, future expectations and benchmarked 
against peer companies in the industry. 

Useful life of intangible assets 
Management have estimated that the useful life of the fair value of the patents acquired on the acquisition of Optibiotix 
Limited in 2013 to be 20 years. Development costs that have been capitalized in line with the recognition criteria of IAS38 
have been estimated to have a useful economic life of 10 years. These estimates will be reviewed annually and revised if the 
useful life is deemed to be lower based on the trading business or any changes to patent law. The net book value of intangible 
assets at the year- end was £1.540m (£2.641m). 

Impairment reviews 
IFRS requires management to undertake an annual test for impairment of indefinite lived assets and, for finite lived assets to 
test  for  impairment  if  events  or  changes  in  circumstances  indicate  that  the  carrying  amount  of  an  asset  may  not  be 
recoverable. Impairment testing is an area involving management judgement, requiring assessment as to whether the 
carrying value of assets can be supported by the net present value of future cash flows derived from such assets using cash 
flow projections which have been discounted at an appropriate rate. In calculating the net present value of the future cash 
flows, certain assumptions are required to be made in respect of highly uncertain matters. The board looked at the current 
order book going forward, the ongoing discussions with current customers and the recent new customers and concluded 
that an impairment of the intangible assets was not applicable for the year to 31 December 2022. The net book value of the 
intangible assets held at 31 December was £1.54m and an adjustment was made of £0.922m to reflect the transfer of 2 patent 
families to Probiotix Health Plc as per note 9. 

Recognition and measurement of the investment in Probiotix Health Plc 
Management have reviewed the nature of the relationship with Probiotix Health Plc in line of the Group's interest moving 
from 100% to 44% by 31 March 2022. Management have had regard to the requirements of IFRS 10 to consider the facts and 
circumstances of the relationship between Optibiotix and Probiotix and not just the shareholding interest. In taking account 
of a range of factors, including Optibiotix's minority representation on the Probiotix board and the terms of a relationship 
agreement entered into between the parties, management have concluded that Optibiotix have significant influence over 
Probiotix but not control. This remains under continuing review as facts and circumstances change. 

As a result of the recognition of the Group's remaining 44% interest at 31 March 2022 at fair value the Group and Company 
balance sheet report material investment holdings in Probiotix Health Plc. 

The  Directors  have  had  regard  to  potential  impairment  of  this  asset.  After  taking  account  of  share  price  movements 
subsequent to the year end, and in particular after the end of the post-IPO lock-in period, the Directors concluded that an 
impairment should be recorded to reflect the movement in share price from 21p at the time of IPO in March 2022 to 6p 
which was the traded price on AQSE Growth after the lock-in period ended. 

Annual Report and Accounts 2021 38

Notes to the Financial Statements (continued)

2. Accounting Policies (continued)

Whilst the Directors believe the share price of 6p is reflective of wider economic uncertainties and a difficult equities market 
rather than any adverse impact in the group's trading prospects, the impairment has been recorded on the basis of a prudent 
approach reflective of market conditions which the Board believe are short term in nature. The Board consider that recently 
depressed share valuations across various international markets reflect significant underpricing and are not reflective of 
asset values. 

3. Segmental Reporting 

In the opinion of the directors, the Group has one class of business, in four geographical areas being that of identifying and developing 
microbial strains, compounds and formulations for use in the nutraceutical industry. The Group sells into to four highly interconnected 
markets, all costs assets and liabilities are derived from the UK location. 

Revenue analysed by market 

Probiotics
Functional Fibres 

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

24
433

457

1,100 
1,113 

 2,213 

Following the loss of control of Probiotix Health Plc on 31 March 2022, all group revenues have been derived from functional fibres. 

Revenue analysed by geographical market 

UK
US 
India
Rest of world

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

136
100
61
160

457

648 
827 
– 
738 

 2,213 

During the reporting period one customer represented £100k (21.9%) of Group revenues. (2021: one customer generated £727k 
representing 32.9% of Group revenues). 

39

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

4. Employees and Directors 

Wages and salaries
Directors’ remuneration
Social security costs
Pension costs

The average monthly number of employees during the period for was as follows: 

Group 
Directors
Research and development

Company 
Directors

Directors' remuneration was as follows: 

Directors’ remuneration
Directors’ share based payments
Benefits in kind
Bonus 

Pension

Total emoluments

Emoluments paid to the highest paid director

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

522
354
66
35

977

636 
494 
83 
44 

 1,257 

Year ended
31 December 2022
No.

Year ended 
31 December 2021 
No. 

6
3

9

6

6

6 
3 

9 

6 

6 

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

354
12
5

–
10

381

151

507 
33 
5 

70 
17 

632 

262 

Annual Report and Accounts 2021 40

Notes to the Financial Statements (continued)

4. Employees and Directors (continued)

Directors’ remuneration 

Details of emoluments received by Directors and key management of the Company for the year ended 31 December 2022 are 
as follows: 

Directors 

                                                            Remuneration   Share based         Pension 
                                                                     and fees       payments            Costs
                                                                         £’000            £’000            £’000

Benefits                     
in Kind             Total
£’000            £’000

S P O’Hara                                                            143                   –                   4
S Christie                                                                 25                   –                   –
R Davidson                                                              55                   –                   –
S Kolyda                                                                  81                   –                   6
C Brinsmead                                                            25                   6                   –
S Hammond                                                            25                   6                   –

Total                                                                      354                 12                 10

4               151
–                 25
–                 55
1                 88
–                 31
–                 31

5               381

Total 
2021 
£’000 

262 
33 
72 
128 
25 
21 

541 

Benefits in kind relate to medical insurance. The number of directors to whom retirement benefits were accruing was 2 (2021: 2). 

5. Net Finance Income/(Costs) 

Finance Income: 
Bank Interest
Finance Cost: 
Loan note interest

Net Finance Income / (Costs)

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

–

–

–

– 

(48) 

(48) 

41

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

6. Expenses – analysis by nature 

Research and development
Directors’ fees & remuneration (Note 4)
Salaries, pension and social security
Auditor remuneration – Group and Company audit fees 
Auditor remuneration-Audit of subsidiaries
Auditor remuneration – non audit fees:tax compliance
Auditor remuneration – non audit fees: other assurance
Brokers & Advisors
Advertising & marketing
Share based payments charge
Bad debt provision
Amortisation of patents and development costs
Patent and IP costs
Consultancy fees
Legal and professional fees
Public Relations costs
Travel costs
Other expenses

Total administrative expenses

7.  Corporation Tax  

Corporation Tax 

Corporation tax credit
Deferred tax movement

Total taxation

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

68
354
623
25
15
8
2
122
84
12
458 
224
88
378
12
80
102
78

64 
469 
512 
23 
22 
7 
3 
209 
42 
60 

288 
115 
262 
28 
68 
16 
213 

2,733

2,488 

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

(38)
(108)

(146)

(75) 
(9) 

(84) 

Annual Report and Accounts 2021 42

Notes to the Financial Statements (continued)

7.  Corporation Tax  (continued)

Analysis of tax expense 

No  liability  to  UK  corporation  tax  arose  on  ordinary  activities  for  the  year  ended  31  December  2022  nor  for  the  year  ended 
31 December 2021. 

Profit (Loss) on ordinary activities before income tax

Loss on ordinary activities multiplied by the standard rate of corporation tax in  
UK of 19% (2021 – 19%)
Effects of: 
Disallowables
Income not taxable
Accelerated depreciation
R&D tax credit claimed
Amortisation
Revenue items capitalised
Other timing differences
Unused tax losses carried forward

Tax credit

Year ended
31 December 2022
£’000

Year ended 
31 December 2021 
£’000 

2,442

466

166
(1,068)
–
(38)
28
–
–
408

(38)

6,177 

1,174 

14 
(1,546) 
– 
(75) 
33 
(37) 
19 
343 

(75) 

The group has estimated losses of £10.8m (2021: £8.41m) in respect of which a deferred tax asset of £2.7m (2021: £2.1m) has not 
been recognised due to the uncertainty of future taxable profits. The unrecognised deferred tax asset has been assessed by reference 
to a rate of 25% which is the UK headline corporation tax rate from 1 April 2023. 

The Group submits claims for R&D tax credits in respect of its research and development activities in respect of microbiome 
modulators and similar products relating to the exploitation of its patent portfolio and potential new patents arising from scientific 
research performed by group employees and its partners. Whilst the Board are confident of recovery of the estimated R&D tax credit, 
there is no certainty that the receivable will be recoverable until HMRC have approved the claim and the enquiry window is closed. 
However, based on the group's history of successful claims over a number of years, the Board are satisfied that the tax receivable is 
recoverable and appropriately recorded.  

Current tax asset – Group 
Balance brought forward
Received during the year 
Prior year adjustment 
Research & development tax credit claimed

43

OptiBiotix Health Plc 

2022
£

191,249
(123,663)
–
37,500

105,086

2021 
£ 

310,435 
(194,663) 
477 
75,000 

191,249 

 
Notes to the Financial Statements (continued)

8. Earnings per share 

Basic earnings per share is calculated by dividing the earnings attributable shareholders by the weighted average number of ordinary 
shares outstanding during the period. 

Reconciliations are set out below: 

                                                                                                                                         2022 

Basic and diluted EPS

Basic EPS
Diluted EPS

Earnings
£’000

2,587
2,587

Weighted average 
Number of shares
No.

88,279,952
93,213,179

                                                                                                                                         2021 

Basic and diluted EPS

Basic EPS
Diluted EPS

Earnings
£’000

6,261,029
6,261,029

Weighted average 
Number of shares
No.

87,574,152
95,536,395

Profit per-share 
Pence 

2.93 
2.78 

Profit per-share 
Pence 

7.15p 
6.55p 

As at 31 December 2022 there were 7,182,907 (2021: 7,632,907) outstanding share options and NIL (2021: 329,336) outstanding 
share warrants. 

Annual Report and Accounts 2021 44

Notes to the Financial Statements (continued)

9.

Intangible assets 

Group

Cost
At 31 December 2020
Additions
Disposals

At 31 December 2021
Additions
Disposals

At 31 December 2022

Amortisation 
At 31 December 2020
Amortisation charge for the year

At 31 December 2021
Amortisation charge for the year
Disposals

At 31 December 2022

Carrying amount 
At 31 December 2022
At 31 December 2021

Development  
Costs and  
Patents 
£’000 

3,672 
193 
– 

3,865 
46 
(1,370) 

2,541 

937 
288 

1,225 
224 
(448) 

1,001 

1,540 
2,640 

The company had no intangible assets during the reporting period. 

Development costs and patents represent cost capitalised in respect of the Group’s intellectual property portfolio and includes the 
costs of registering and maintaining patents as well as capitalised development costs. All intangible assets relate to the Group’s 
principal activities. 

Disposals in the year relate to two patent families relating to probiotic patents owned by Probiotix Limited and therefore which 
were derecognised upon the group's loss of control of Probiotix Health Plc. This disposal has formed part of the gain on loss on 
disposal reported in the income statement. 

45

OptiBiotix Health Plc 

 
 
Notes to the Financial Statements (continued)

10. Property, plant and equipment 

Group

Cost
At 31 December 2020
Additions
Disposals

At 31 December 2021
Additions
Disposals

At 31 December 2022

Depreciation 
At 31 December 2020
Charge for the year

At 31 December 2021
Charge for the year

At 31 December 2022

Carrying amount 
At 31 December 2022
At 31 December 2021

£ 

8,461 
– 
– 

8,461 
– 
– 

8,461 

8,461 
– 

8,461 
– 

8,461 

– 
– 

The company had no fixed assets during the reporting period. 

11. Investments 

Group 

Set out below is the investment in Skinbiotherapeutics PLC. The investment was treated as an associate of the group until 2 November 
2020, after which time the shareholding dropped to 24.65% and recalculated as an equity investment. The Group records its 
investment in Skinbiotheraputics plc at fair value and is remeasured by reference to its closing price on AIM at each reporting date. 
The share price at 31 December 2022 was 15.5p. 

During the year, a small holding of shares was disposed to generate proceeds of £25k with original cost of £8k. 

Investments 
At the beginning of the period
Revaluations 
Disposal of shares during year

At 31 December

2022
£’000 

13,651
(8,620)
(9)

5,022

2021 
£’000 

8,962 
7,501 
(2,812) 

13,651 

Annual Report and Accounts 2021 46

 
Notes to the Financial Statements (continued)

11. Investments (continued)

Investment in Associate 

On 31 March 2022, ProBiotix Health Plc ( “PBX”) the parent company of ProBiotix Limited listed on the AQSE Growth Market. The 
listing of PBX on AQSE, together with the issue of a dividend in specie and issue of new shares, means that PBX is now considered 
an associate for accounting purposes with its revenues and costs removed post listing and only OptiBiotix’s (44%) proportion of its 
profit and loss included in the Group’s accounts under the equity method of accounting. The step-down from being a subsidiary to 
an associate resulted in the revaluation of the remaining interest held in PBX at the listing price and a gain on disposal of a subsidiary 
recognised in the income statement. A gain of £21.647m was recorded in the income statement. 

An assessment was undertaken to assess whether the Company had defacto control over PBX during the period considering Board 
representation, financing arrangements , the Relationship agreement and the other shareholdings in PBX. Based on the assessment 
it was concluded that the Company only had significant influence and that PBX was an associate in the period. The Relationship 
agreement sets out costs that are being incurred by the Group that are being recharged to PBX. 

At 31 March 2022 the Group held 53,533,333 shares in Probiotix Health Plc, valued at the IPO price of 21p resulting in a deemed cost 
of investment in associate of £11.24m. As an associate, the Group's investment is equity accounted and the Group's 44% share of 
loss was deducted from this carrying value. 

Investment in Associate 

Investments 
At the beginning of the period
Additions 
Deemed cost on reclassification from subsidiary
Impairment in the period
Share of result for the period (see below)

At 31 December

2022
£’000 

–

11,242
(8,030)
(83)

3,129

2021 
£’000 

– 

– 
– 
– 

– 

PBX is registered in United Kingdom and is in the Health food sector. 

Set  out  below  is  financial  information  on  PBX  set  out  in  its  IFRS  financial  statements  for  the  period  from  incorporation  on 
4 November 2021 to 31 December 2022. 

Revenue
Loss from continuing operations
Total comprehensive income
Current assets
Current Liabilities
Non-current liabilities 
44% share of total comprehensive loss.

47

OptiBiotix Health Plc 

2022 
£’000 

1,308 
(237) 
(189) 
2,311 
(307) 
(89) 
(83) 

 
Notes to the Financial Statements (continued)

11. Investments (continued)

Company Investments 

Listed Investments 
At the beginning of the period
Additions
Revaluations
Disposal of shares during year

Investment in subsidiaries 
At the beginning of the period
Additions
Impairment
Disposals

At 31 December

Company Investment in Associate 

At the beginning of the period
Reclassification to associate
Provision against value of associate

At 31 December

2022
£’000 

13,651
–
(8,620)
(9)

5,022

2,081
16
(50) 
(61) 

1,986

7,008

2022
£’000 

60
11,182
(8,030)

3,212

2021 
£’000 

8,962 
– 
7,501 
(2,812) 

13,651 

2,081 
– 

2,081 

15,732 

2021 
£’000 

– 
– 
– 

– 

The Company holds listed investments at fair value, and investments in subsidiaries and associates at cost less impairment. The fair 
value of the Company's investment in Probiotix Health Plc upon losing control was set as deemed cost. 

The Directors have had regard to potential impairment of this group's investment in Probiotix. After taking account of share price 
movements subsequent to the year end, and in particular after the end of the post-IPO lock-in period, the Directors concluded that 
an impairment should be recorded to reflect the movement in share price from 21p at the time of IPO in March 2022 to 6p which 
is an approximation to the traded price on AQSE Growth after the lock-in period ended.  

Whilst the Directors believe the share price of 6p is reflective of wider economic uncertainties and a difficult equities market rather 
than any adverse impact in the group's trading prospects, the impairment has been recorded on the basis of a prudent approach 
reflective of market conditions which the Board believe are short term in nature. The Board consider that recently depressed share 
valuations across various international markets reflect significant under pricing and are not reflective of asset values. 

An impairment charge of £8.03m has been recorded in the income statement as a separate line item. The impairment assessment 
was made by reference to fair values using Level 1 inputs on the Fair Value Hierarchy, being observable traded prices on the AQSE 
Growth exchange. 

During the period an impairment of £50,000 was raised against the Company's investment in The Healthy Weight Loss Company 
Limited as the board intend to wind up this company which has minimal assets and no trading activity. 

Annual Report and Accounts 2021 48

Notes to the Financial Statements (continued)

11. Investments (continued)

The entities listed below have share capital consisting solely of ordinary shares, which are held by the Group. The country of 
incorporation is also the principal place of business and the proportion of ownership interest is the same as the proportion of voting 
rights held. 

As at 31 December 2022 the Company directly held the following subsidiaries: 

Name and                                                                                       Country of 
Registered office address                                                                  incorporation
of company                                       Principal activities                    and place of business

OptiBiotix Limited                              Research & Development          United Kingdom
Innovation Centre 
Innovation Way, Heslington 
York, YO10 5DG 

Optibiotix Health India                        Health foods                            India
Private Limited 
House NO.243, Mcd Colony,  
Vivekanand Puri Sarai, 
Rohilla City, Delhi CITY, DELHI,  
North Delhi, Delhi, India, 110007 

Proportion of 
equity interest 

100% of ordinary shares 

100% of ordinary shares 

The Healthy Weight Loss                     Health foods                            United Kingdom
Company Limited 
Office 7, 35/37 Ludgate Hill,  
London, England, EC4M 7JN 

68% of ordinary shares 

12. Inventories 

                                                                                         Group                                                          Company 
                                                                          2022
                                                                         £’000

2022
£’000

2021
£’000

Finished goods                                                        178

102

–

During the period £213k (2021: £1,090k) has been expensed to the income statement. 

13. Trade and other Receivables 

                                                                                         Group                                                         Company 
                                                                          2022
Non-current                                                       £’000

2022
£’000

2021
£’000

Amounts owed by group undertakings                         –

                                                                               –

Current 
Accounts receivable                                                379
Other receivables                                                   131
Prepayments and accrued income                              11

                                                                            521

49

OptiBiotix Health Plc 

–

–

1,415
82
56

1,553

–

–

–
17
8

25

2021 
£’000 

– 

2021 
£’000 

318 

318 

– 
40 
26 

66 

 
 
 
Notes to the Financial Statements (continued)

13. Trade and other Receivables (continued)

During the period 1 January 2022 to 31 March 2022 Optibiotix Health PLC loaned Probiotix Limited £150,000, to finance working 
capital costs in the period up to the listing of Probiotix Health Group plc. During the year £203,835 was repaid. The balance due to 
Probiotix Limited at 31 December 2022 of £10,137 (2021 owing: £53,835) was repaid post year end. There was no interest charged 
during the year. 

During the year Optibiotix Health PLC loaned Optibiotix Limited £1,220,000 to finance working capital costs. Optibiotix Limited 
recharged Optibiotix Health PLC £373,426 for salary costs. The balance at the year end of £846,574 (2021, £931,903) was cancelled. 
There was no interest charged during the year. This does not impact on the consolidated Group accounts. 

During the year Optibiotix Limited recharged Probiotix Health Plc £23,139 for directors’ fees. Optibiotix Limited received a recharge 
from Probiotix Health Plc for admin costs of £148. The balance at the year end of £22,991 was received after the year end. There was 
no interest charged during the year. 

During the year Optibiotix Limited transactions with Probiotix Limited were as follows: 

•

•

•

£440,663 for salaries and administration costs; 

£60,676 income received on behalf of Probiotix limited; and 

£544,177 repayments received. 

There was no interest charged during the year. The remaining balance of £30,146 was received after the year end. 

14. Cash and Cash Equivalents 

                                                                                         Group                                                         Company 
                                                                          2022
                                                                         £’000

2022
£’000

2021
£’000

Cash and bank balances                                        1,052

2,007

865

All cash is held in demand deposits with large UK banks. 

15. Called Up Share Capital 

Issued share capital comprises: 

Ordinary shares of 2p each – 91,190,661 (2021: 87,940,601)

During the period the Company issued ordinary shares of £0.02 each listed below: 

Exercise of warrants at exercise price of £0.08
Exercise of warrants at exercise price of £0.08
Issue of equity via subscription at a price of £0.16

2022
£’000 

1,824

1,824

Date 

27/01/2022
09/03/2022
05/12/2022

2021 
£’000 

1,705 

2021 
£’000 

1,759 

1,759 

Number 

125,000 
60 
3,125,000 

3,250,060 

Annual Report and Accounts 2021 50

Notes to the Financial Statements (continued)

16. Reserves 

Share capital is the amount subscribed for shares at nominal value. Share premium represents amounts subscribed for share capital 
in excess of nominal value, net of expenses. 

The convertible debt reserve is the equity component of the convertible loan notes that have been issued. 

Merger relief reserve arises from the 100% acquisition of OptiBiotix Limited on 5 August 2014 whereby the excess of the fair value 
of the issued ordinary share capital issued over the nominal value of these shares is transferred to this reserve in accordance with 
section 612 of the Companies Act 2006. 

Retained earnings represents the cumulative profits and losses of the group attributable to the owners of the company net of 
distributions paid. 

Share based payment reserve represents the cumulative amounts charged in respect of unsettled warrants and options issued. 

17. Trade and other payables 

                                                                                         Group                                                         Company 
                                                                          2022
Current                                                              £’000

2022
£’000

2021
£’000

Accounts Payable                                                    191
Accrued expenses                                                    70
Other payables                                                         17

Total trade and other payables                                 278

424
175
3

602

34
39
10

83

2021 
£’000 

18 
23 
– 

41 

18. Deferred Tax 

Deferred tax is provided, using the liability method, on temporary differences at the statement of financial position date between 
the tax base of assets and liabilities and their carrying amounts for financial reporting purposes. 

Deferred tax is calculated in full on temporary differences under the liability method using a tax rate of 25% (2021: 25%). 

The movement on the deferred tax account is as shown below: 

At 31 December 
Movement in the period

At 31 December 

2022
£’000

552
(187)

365

2021 
£’000 

561 
(9) 

552 

Deferred tax assets have not been recognised in respect of tax losses and other temporary differences giving rise to deferred tax 
assets as the directors believe there is uncertainty over the timing of future taxable profits. Further details of available losses are set 
out in note 7. 

19. Convertible Loan Notes  

The Company’s former subsidiary Probiotix Health Plc issued 1,025,000 floating rate convertible loan notes (CLN) for £1,025,000 on 
11 December 2018. The notes were convertible into ordinary shares of the Company and converted into shares immediately prior 
to the occurrence of a listing of the company, or repayable on December 2023. The conversion rate is 1 share for each note held at 
an amount which is equal to 50% of the listing price. 

OptiBiotix Health Plc had subscribed 250,000 of the CLN for £250,000 

The loan notes were converted as part of the listing process for Probiotix Health Plc on 31 March 2022. 

51

OptiBiotix Health Plc 

 
Notes to the Financial Statements (continued)

20. Related Party Disclosures 

Transactions and balances with Probiotix Group are set out in note 13. 

21. Ultimate Controlling Party 

The Board consider that there is no overall controlling party. 

22. Share Based payment Transactions 

(i) Share options 

The Company had introduced a share option programme to grant share options as an incentive for employees of the subsidiaries. 

Each share option converts into one ordinary share of the Company on exercise. No amounts are paid or payable by the recipient 
on receipt of the option and the Company has no legal obligation to repurchase or settle the options in cash. The options carry 
neither rights to dividends nor voting rights prior to the date on which the options are exercised. Options may be exercised at any 
time from the date of vesting to the date of expiry. 

Movements in the number of share options outstanding and their related weighted average exercise prices are as follows: 

                                                                                       Number of options                                 Average exercise price 
                                                                                    2022                        2021                        2022
                                                                                      No.                         No.                             £

2021 
£ 

Outstanding at the beginning of the period                 7,632,907                 8,032,907                         0.18
Granted during the period                                           500,000                             –                         0.02
Forfeited/cancelled during the year                              (950,000)                (400,000)                         0.70
Exercised during the period                                                   –                             –                             –

Outstanding at the end of the period                         7,182,907                 7,632,907                       0.092

0.21 
– 
0.785 
– 

0.17 

For the share options issued in 2014 vesting conditions dictate that half will vest if the middle market quotation of an existing 
Ordinary share is 16p or more on each day during any period of at least 30 consecutive Dealing days and half will vest when a 
commercial contract is signed. The two conditions are not dependent on each other and will vest separately. 

For the share options issued in 2015 vesting conditions dictate that some of the options will vest if the middle market quotation of 
an existing Ordinary share is 40p or more on each day during any period of at least 30 consecutive Dealing days and some will vest 
if certain revenue targets are met or if certain scientific studies are completed. The conditions are not dependent on each other and 
will vest separately. 

For the share options issues in 2017 vesting conditions dictate that the options will vest if certain revenue conditions are met. 

For the share options issues in 2020 vesting conditions dictate that the options will vest if certain revenue conditions are met. 

For share options issued in 2022 The Company has agreed with a number of option holders to surrender their existing options in 
return for Nominal Value Options over half the number of shares of their existing options, which will be subject to a combination of 
performance and time-based vesting criteria. This ensures a continued focus on commercial revenues and shareholder value creation. 
New options will be granted on a similar basis going forward. Options granted to non-executive directors will be subject to time-
based vesting. 

The share options outstanding at the period end had a weighted average remaining contractual life of 830 days (2021: 1,241 days) 
and the maximum term is 10 years. 

The share price per share at 31/12/22 was £0.13 (31/12/2021: £0.46). 

Annual Report and Accounts 2021 52

Notes to the Financial Statements (continued)

22. Share Based payment Transactions (continued)

Where share options were cancelled in the period and replaced with share options with revised terms, the Board have considered 
this set of transactions as a modification of share based payment arrangements and have therefore considered whether any 
incremental value arises as a result of the grant of modified awards. Having performed an assessment the Board have concluded 
that no incremental value fair is required and therefore no charge has been recognised. In respect of replacement options which 
include market based vesting conditions in respect of revenue targets, the Board have determined that the value of this proportion 
of shares have immaterial value in light of the Group's results for the 2022 accounting period in which they were granted.  

(i) Warrants 

On 20 February 2014, an open offer was made to the potential investors to subscribe for 203,380,942 new ordinary shares of £0.0001 
each  at  £0.0001  each.  On  a  1:1  basis,  warrants  attach  to  any  shares  issued  under  the  open  offer  convertible  at  any  time  to 
30 November 2018 at £0.0004 per shares. 

On 4 August 2014, the warrants in issue were consolidated in the ratio of 200:1 as part of the share reorganisation. 

At a meeting of warrant holders on 24 January 2017 it was agreed to extend the exercise period for all remaining warrants to 
28 January 2022 and 19 February 2022 

Movements in the number of share warrants outstanding and their related weighted average exercise prices are as follows: 

                                                                                        Number of warrants                               Average exercise price 
                                                                                    2022                        2021                        2022
                                                                                      No.                         No.                             £

2021 
£ 

Outstanding at the beginning of the period                    329,336                   329,386                         0.08
Exercised                                                                  (125,060)                            –                         0.08
Cancelled                                                                   204,276                             –                             – 

Outstanding at the end of the period                                      –                   329,386                             –

0.08 
0.08 

0.08 

There were no warrants in issue at 31 December 2022. 

A charge of £Nil (2021: £60,288) has been recognised during the year for the share based payments over the vesting period. 

23. Financial Risk Management Objectives and Policies  

The Group’s financial instruments comprise cash balances and receivables and payables that arise directly from its operations. 

The main risks the Group faces in respect of its financial statements are liquidity risk and credit risk. 

The Board regularly reviews and agrees policies for managing each of these risks. The Group’s policies for managing these risks are 
summarised below and have been applied throughout the period.  

Interest risk 

The Group is not exposed to significant interest rate risk as it has limited interest bearing liabilities at the year end. 

The group's financial assets do not bear interest. 

53

OptiBiotix Health Plc 

 
23. Financial Risk Management Objectives and Policies (continued)

Credit Risk 

The Group try to limit the credit risk by dealing with larger companies and also asking new smaller customers to provide a deposit 
with the purchase order. 

Management have regard to credit exposures when entering into new contracts and seek to agree settlement terms on all contracts. 
Credit exposure is regularly monitored by management and any overdue debts are followed up as part of the group's credit control 
procedures. Where a debt becomes significantly overdue, management have regard to credit loss provisions to reflect the existence 
of expected credit losses, taking account of forward looking information as well as the pattern of cash collections for that category 
of customer. 

At 31 December 2022 one material debt is overdue, however management have negotiated revised terms and expect to resolve 
the outstanding amount within 2023. 

Having taken account of the nature of the relationship with the customer and the pattern of repayments since the receivable was 
raised, the Directors expect the amount to be recovered in full, however a credit loss provision of £60,000 has been created to reflect 
the impact of wider economic uncertainties over the projected collection period. 

The Board consider a default to have occurred when a receivable passes 60 days beyond agreed credit terms, at which point regard 
is had to the specific characteristics of the debtor in assessing exposure to material credit risk and therefore the requirement to 
create a loss provision.  

Liquidity risk 

Liquidity risk is the risk that Group will encounter difficulty in meeting these obligations associated with financial liabilities. 

The responsibility for liquidity risks management rest with the Board of Directors, which has established appropriate liquidity risk 
management framework for the management of the Group’s short term and long-term funding risks management requirements. 

During the period under review, the Group has not utilised any borrowing facilities. 

The Group manages liquidity risks by maintaining adequate reserves by continuously monitoring forecast and actual cash flows, 
and by matching the maturity profiles of financial assets  and liabilities. 

Capital risk 

The Group’s objectives when managing capital are to safeguard the ability to continue as a going concern in order to provide returns 
for shareholders and benefits to other stakeholders and to maintain an optimal capital structure to reduce the cost of capital. 

24. Post Balance Sheet Events 

Subsequent to the period end, the share price of the group's associate Probiotix Health Plc was trading in the region of 5-7p, 
representing a material reduction since the IPO price of 21p at 31 March 2022. The Directors have had regard to the financial reporting 
impacts and further detail is given in Note 11.

Annual Report and Accounts 2021 54

Notice of Annual General Meeting

Notice is hereby given that the Annual General Meeting of OptiBiotix Health PLC (the “Company”) will be held at the offices of 
Walbrook PR Ltd, 75 King William Street, London, EC3V 9HD on 26 July 2023 at 11:00 am for the following purposes: 

1.

2.

3.

4.

To receive the Company’s Report and Accounts for the year ended 31 December 2022. 

To re-elect Sofia Kolida, who retires by rotation, as a Director. 

To re-elect Sean Christie, who retires by rotation, as a Director. 

To appoint Gravita Audit Limited as auditors of the Company and to authorise the Directors to determine their remuneration. 

Special Business 

To consider and, if thought fit, to pass the following resolutions as to the resolution numbered 5 as an Ordinary Resolution and as 
to the resolutions numbered 6 as Special Resolutions: 

5.

6.

THAT the Directors be and they are hereby authorised generally and unconditionally for the purposes of Section 551 of the 
Companies Act 2006 (the “Act”) to exercise all powers of the Company to allot shares in the Company or to grant rights to 
subscribe for, or to convert any security into, shares in the Company (such shares and/or rights being “Relevant Securities”) 
up to an aggregate nominal amount of £607,937.57 being one third of the current issued share capital, provided that this 
authority shall, unless renewed, varied or revoked by the Company, expire on the date being the earlier of the date 15 months 
after the passing of this Resolution and the conclusion of the Annual General Meeting of the Company to be held in 2024, 
save that the Company may, before such expiry, make offers or agreements which would or might require Relevant Securities 
to be allotted and the Directors may allot Relevant Securities in pursuance of such offer or agreement notwithstanding that 
the authority conferred by this Resolution has expired. 

This authority shall be in substitution for and shall replace any existing authority pursuant to Section 551 of the Act to the 
extent not utilised at the date this resolution is passed. 
THAT, subject to and conditional upon the passing of resolution 5, the Directors be and they are hereby generally empowered 
pursuant to Section 570 of the Act to allot equity securities (as defined in Section 560 of the Act) for cash pursuant to the 
authority conferred under Resolution 5 above as if sub-section 561(1) of the Act did not apply to such allotment, provided 
that this power shall be limited to: 

(a)

the allotment of equity securities in connection with a rights issue or any pre-emptive offer in favour of holders of 
ordinary shares in the Company where the equity securities attributable to the respective interests of such holders are 
proportionate (as nearly as maybe) to the respective numbers of ordinary shares held by them on the record date for 
such allotment subject to such exclusions or other arrangements as the Directors may deem necessary or expedient 
to deal with fractional entitlements or any legal or practical difficulties under the laws of, or the requirements of, any 
regulatory body or stock exchange of any overseas territory or otherwise; 

(b)

the allotment (otherwise than pursuant to sub-paragraph (a) above) of equity securities up to an aggregate nominal 
value of £547,143.82 being 30% of the current issued share capital; 

and shall expire on the date being the earlier of the date 15 months after the passing of this Resolution and the conclusion 
of the Annual General Meeting of the Company to be held in 2024, provided that the Company may before such expiry 
make an offer or agreement which would require equity securities to be allotted in pursuance of such offer or agreement as 
if the power conferred hereby had not expired and provided further that this authority shall be in substitution for and 
supersede and revoke any earlier power given to directors. 

By Order of the Board

Stephen O’Hara
27 June 2023

55

OptiBiotix Health Plc 

Registered Office: 
Innovation Centre 
Innovation Way 
Heslington 
York 
YO10 5DG 

 
Explanatory Notes to the 
Notice of Annual General Meeting

Notes:

1.

2.

3.

4.

5.

A member of the Company is entitled to appoint a proxy or proxies to attend, speak and vote at the meeting in his stead. 
A member may appoint more than one proxy provided each proxy is appointed to exercise rights attached to different shares. 
A member may not appoint more than one proxy to exercise rights attached to any one share. A proxy does not need to be 
a member of the Company. 

To be effective Forms of Proxy can be registered as follows: 
•         by logging on to www.shareregistrars.uk.com, clicking on the “Proxy Vote” button and then following the on-screen 

instructions; 

•         by post or by hand to Share Registrars Limited, 3 The Millennium Centre, Crosby Way, Farnham, Surrey GU9 7XX using 

the proxy form accompanying this notice; 

•         in the case of CREST members, by utilising the CREST electronic proxy appointment service in accordance with the 

procedures set out in note 5 below. 

In order for a proxy appointment to be valid the proxy must be received by Share Registrars Limited by 11:00 am on 
24 July 2023. 

To change your proxy instructions simply submit a new proxy appointment using the methods set out above and in the 
notes to the Form of Proxy. Note that the cut-off times for receipt of proxy appointments (see above) also apply in relation 
to amended instructions; any amended proxy appointment received after the relevant cut-off time will be disregarded. 

To be entitled to vote at the meeting (and for the purpose of the determination by Company of the number of votes they 
may cast), members must be entered in the Register of members at 11:00am on 24 July 2023 (“the specified time”). If the 
meeting is adjourned to a time not more than 48 hours after the specified time applicable to the original meeting, that time 
will also apply for the purpose of determining the entitlement of members to attend and vote (and for the purpose of 
determining the number of votes they may cast) at the adjourned meeting. If however the meeting is adjourned for a longer 
period then, to be so entitled, members must be entered on the Company’s Register of Members at the time which is not 
less than 48 hours before the time fixed for the adjourned meeting or, if the Company gives notice of the adjourned meeting, 
at the time specified in that notice. 

CREST members who wish to appoint a proxy or proxies through the CREST electronic proxy appointment service may do 
so for the General Meeting and any adjournment(s) thereof by using the procedures described in the CREST Manual. CREST 
Personal Members or other CREST sponsored members, and those CREST members who have appointed a voting service 
provider(s) should refer to their CREST sponsor or voting service provider(s), who will be able to take the appropriate action 
on their behalf. In order for a proxy appointment or instruction made using the CREST service to be valid, the appropriate 
CREST  message  (a “CREST  Proxy  Instruction”)  must  be  properly  authenticated  in  accordance  with  CRESTCO  Limited’s 
specifications and must contain the information required for such instructions, as described in the CREST Manual. The 
message, regardless of whether it relates to the appointment of a proxy or to an amendment to the instruction given to a 
previously appointed proxy must, in order to be valid, be transmitted so as to be received by the issuer’s agent 7RA36 by the 
latest time(s) for receipt of proxy appointments specified above. For this purpose, the time of receipt will be taken to be the 
time (as determined by the timestamp applied to the message by the CREST Applications Host) from which the issuer’s agent 
is able to retrieve the message by enquiry to CREST in the manner prescribed by CREST. After this time, any change of 
instructions to proxies appointed through CREST should be communicated to the appointee through other means. 

CREST members and, where applicable, their CREST sponsors or voting service providers should note that CRESTCO Limited 
does not make available special procedures in CREST for any particular messages. Normal system timings and limitations will 
therefore apply in relation to the input of CREST Proxy Instructions. It is the responsibility of the CREST member concerned 
to take (or, if the CREST member is a CREST personal member or sponsored member or has appointed a voting service 
provider(s), to procure that his or her CREST sponsor or voting service provider(s) take(s)) such action as shall be necessary to 
ensure that a message is transmitted by means of CREST by any particular time. In this connection, CREST members and, 
where applicable, their CREST sponsors or voting service providers are referred, in particular, to those sections of the CREST 
Manual concerning practical limitations of the CREST system and timings.The Company may treat as invalid a CREST Proxy 
Instruction in the circumstances set out in Regulation 35(5)(a) of the Uncertificated Securities Regulations 2001. 

Annual Report and Accounts 2021 56

Explanatory Notes to the Notice of Annual General Meeting (continued)

Resolution 1 

The Directors are required by law to present to the meeting the Audited Accounts and Directors’ Report for the period ended 
31 December 2022. 

Resolutions 2-3 

Each of the Company’s Directors listed in this resolution offer themselves up for re-appointment under the terms of the Company’s 
articles of association which state that each director must offer himself or herself up for re-appointment every three years. 

Resolution 4 

The  Auditors  are  required  to  be  re-appointed  at  each  Annual  General  Meeting  at  which  the  Company’s  Audited  Accounts 
are presented. 

Resolution 5 

Under the Act, the Directors may only allot shares if authorised to do so. Whilst the current authority has not yet expired, it is customary 
to grant a new authority at each Annual General Meeting. Accordingly, this resolution will be proposed as an ordinary resolution to 
grant a new authority to allot or grant rights over up to £607,937.57 in nominal value of the Company’s unissued share capital. If 
given, this authority will expire at the Company’s next annual general meeting following the date of the resolution. Although the 
Directors currently have no present intention of exercising this authority, passing this resolution will allow the Directors flexibility to 
act in the best interests of the Company’s shareholders when opportunities arise. 

Resolution 6 

The Directors require additional authority from the Company’s shareholders to allot shares where they propose to do so for cash 
and otherwise than to the Company’s shareholders pro rata to their holdings. This resolution will give the Directors power to issue 
new ordinary shares for cash other than to the Company’s shareholders on a pro rata basis 

(i)

(ii) 

by way of a rights or similar issue or 

with a nominal value of up to £547,143.82. This resolution will be proposed as a special resolution. 

57

OptiBiotix Health Plc 

 
optibiotix.com

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