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Polarean Imaging plc

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FY2018 Annual Report · Polarean Imaging plc
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Polarean Imaging Plc 
Group Annual Report & Accounts 2018 

Company Number 10442853 

 
 
 
 
 
 
 
 
 
 Group Annual Report and Financial Statements 

for the year ended 31 December 2018 

Contents 

Page 

2 

3 

Company Information 

Chairman’s Statement 

5   Chief Executive Officer’s Statement 

7 

Strategic Report 

15  Directors’ Report 

20  Corporate Governance Statement 

25  Remuneration Committee Report 

27  Audit Committee Report 

28 

Independent Auditors’ Report  

31  Consolidated Statement of Comprehensive Income 

32  Consolidated Statement of Financial Position 

33  Company Statement of Financial Position 

34  Consolidated Statement of Changes in Equity 

35  Company Statement of Changes in Equity 

36  Consolidated Statement of Cash Flows 

37  Company Statement of Cash Flows 

38  Notes to the Financial Statements 

58  Notice of the Annual General Meeting 

Polarean Imaging plc 
1 

 
 
 
 Company Information 

Directors & Advisers 

Directors 

  Richard Morgan 
Richard Hullihen 
Kenneth West 
Bastiaan Driehuys, PH.D. 
Robert (“Bob”) Bertoldi 
Jonathan Allis 
Juergen Laucht 

Non-Executive Chairman 
Chief Executive Officer 
Chief Operating Officer 
Chief Technology Officer 
Non-Executive Director 
Non-Executive Director 
Non-Executive Director 

Company Secretary 

  Stephen Austin 

Chief Financial Officer 

  Charles Osborne 

Registered Office 

27-28 Eastcastle Street 
London, W1W 8DH 

Company Number 

  Registered in England and Wales Number 10442853 

Nominated Adviser and 
Broker 

Independent Auditor 

Registrar 

Bankers 

  SP Angel Corporate Finance LLP 

Prince Frederick House 
35-39 Maddox Street 
London  
W1S 2PP 

  Crowe U.K. LLP  
St Brides House  
10 Salisbury Square  
London  
EC4Y 8EH 

  Share Registrars Limited 

The Courtyard 
17 West Street Farnham  
Surrey  
GU9 7DR 

  Silicon Valley Bank 
Alphabeta Building 
14-18 Finsbury Square  
London  
EC2A 1BR 

Legal Advisers to the Group 

  Reed Smith LLP 

Financial Public Relations and 
Investor Relations 

The Broadgate Tower 
20 Primrose Street 
London  
EC2A 2RS 

  Walbrook PR 

4 Lombard Street 
London  
EC3V 9HD 

Polarean Imaging plc 
2 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Chairman’s Statement 

The most immediate challenge facing the  Company upon completion of the IPO in March 2018 was the start of the 
clinical  trials.  Satisfactory  completion  of  the  clinical  trials  is  a  necessary  condition  for  successful  commercial 
development as we go forward, although it is far from being the only key to our success.  

The trials are now nearing completion.  No clinical trial is ever straight forward and the team has worked closely with 
the several advisors that have guided the design, launch and prosecution of the trials, to ensure that they are proceeding 
to plan. As we announced on 11 June 2019, we have elected to bring online a third trial site and we are grateful to our 
valued collaborators at the University of Cincinnati for their help with the initiation of this site, which we believe should 
ensure the timely completion of enrolment in both trials  by the end of the third quarter of 2019. That should allow us to 
file our New Drug Application (“NDA”) with the FDA and, assuming approval, is expected to enable us to make our first 
commercial unit sales by the end of 2020. 

While the clinical trials we are conducting are a critical part of the business plan, they are not the only part. The Company 
has continued to meet expectations in relation to sales of additional pre-clinical units to existing and new institutional 
customers. This has brought the total number of systems in use or on order to 24 and the majority of those are with 
leading medical institutions who are conducting research and additional clinical trials into the use of hyperpolarized 129 
Xenon using MRI (129Xe MRI).  At present there are at least 42 clinical trials into the use of  129Xe MRI showing on the 
FDA website.  We were particularly pleased to be able to announce on 21 May 2019 receipt of the third year of grant 
from the NIH / SBIR which is funding the work being done jointly with Cincinnati Children’s Hospital into the use of 129Xe 
MRI  in  paediatric  populations.  Alongside  the  work  being  done  by  SickKids  in  Canada,  and  others,  into  pediatric 
populations  we  believe  we  can  look  forward  to  129Xe  MRI  making  a  materially  positive  medical  contribution  to  the 
diagnosis and monitoring of treatment of pulmonary health conditions in children, including those suffering from cystic 
fibrosis. 

During the year a number of key advances were made in applications of the technology to gas exchange and beyond.  
Many of the medical issues that arise in patients with compromised pulmonary function occur as a result of deficiencies 
in the body’s ability to absorb oxygen out of air and into the bloodstream.  Some of these medical issues, like Idiopathic 
Pulmonary  Fibrosis  (“IPF”),  cannot  readily  be  diagnosed  accurately  using  existing  techniques  but  they  are  serious 
conditions  that  are  increasingly  being  targeted  by  the  pharmaceutical  companies  for  drug  development.  Accurate 
diagnosis and monitoring is one critical aspect of the effective medication of these conditions and we believe 129Xe MRI 
can  help  to  address  this  unmet  medical  need.  In  late  2018  we  extended  our  collaboration  with  Duke  University  by 
securing  the  intellectual  property  rights  to  an  entirely  new  application,  in  pulmonary  vascular  disease,  including 
pulmonary arterial hypertension (“PAH”). We are already in discussion with several companies that have developed 
medications for PAH and other conditions (COPD and asthma for example) in the expectation that 129Xe MRI can make 
a significant difference in both the development of new drugs and in the management of these conditions in the clinic. 

Our first nine months as a public company included the completion of two additional financing rounds, the second of 
which  closed  at  the  end  of  2018.  The  capital  market  environment  for  small  medical  technology  companies  was 
challenging throughout the year and the Polarean IPO was one of very few successful public listings in the sector on 
the AIM market in 2018. We were fortunate to be able to complete those financing rounds, which provided  additional 
support for the clinical trials.   

We believe  that partnering  with  pharmaceutical  and  other companies  to  facilitate  the  development  and  use  of  their 
products is a key part of Polarean’s future development. We already have relationships with several companies that 
have expressed an interest in partnering with us. Such relationships can help us expand our development activities in 
the near term and, following FDA approval, to expand access to and support a presence in deployment of Polarean’s 
technology as we reach into the clinical setting and help expand the treatment options available to patients. We have 
also consistently stated our intention to access markets outside the United States through partnerships and we are 
pleased to note a growing interest in partnering opportunities to expand our geographical footprint in that way. 

The  team has  done  a great  job  in  efficiently  producing  and  shipping new  systems  to  our  customers,  while  working 
closely with our installed base to provide service and support to their existing systems.  As our installed base grows, 
this becomes a proportionally larger challenge, in addition to the continuing work in hand to improve the design and 
performance of our systems and to plan for the future evolution of the product.  The manufacture of the equipment was 
successfully outsourced and the last five machines have been built under the GMP standards which are required both 
for pivotal clinical trials and the clinical use of this technology.   

Polarean Imaging plc 
3 

 
 
 
 
 
 
 
 
 
 
 
 
 
 Chairman’s Statement 

Continued 

We were delighted to be able to add Chuck Osborne to our team as Chief Financial Officer in April 2019 and welcome 
his help in addressing the many challenges that lie ahead as we grow the Company. 

We hope to be able to announce the completion of our clinical trials in the next few months and look forward to working 
with the FDA when we seek approval to allow marketing of the technology next year. This will be another major and 
exciting phase change for the Company which we will report on more fully in the coming months.  We continue to look 
forward with determination and high confidence in the strength of the technology and the commitment of the team. 

Richard Morgan 
Non-Executive Chairman 

26 June 2019 

Polarean Imaging plc 
4 

 
 
 
 
 
 
 
 
 
 
 Chief Executive Officer’s Statement 

2018 – Year of Development and Accomplishment 

Polarean and its subsidiaries (the ‘Group’) began their first full year focused on preparation for the Phase III Clinical 
trials. Having finalised contracts with Contract Research Organisations and with the two university sites for the trials, 
we planned and executed a Pilot Study which closely matched the trial protocol in order to prove that the structure and 
specifications of the trials were met in the “non-inferiority” structure of the trial. We conducted that study at one of the 
two trial sites, using the same equipment and methods of the Phase III trial protocol. That study was successful and 
gave the Group the confidence to initiate the trials. 

The Opportunity 

The  US  Healthcare  system  annual  burden  of  pulmonary  disease  is  US$150  billion  and  the  Directors  still  see  a 
tremendous opportunity to bring our technology’s quantitative, reproducible, non-invasive method for diagnostic and 
therapeutic guidance to medicine. We have begun to develop the healthcare economic analyses to support the adoption 
by providers of our technology, working with experts in the field. Over the planning horizon of the first 48 months post 
commercial launch, the Group intends to address the high end of US academic and teaching hospital market segment, 
which comprises approximately the top 1,000 institutions nationally. The combined addressable market there for our 
products approaches US$500 million. 

While  working  to  achieve  FDA  approval  for clinical use,  Polarean continues  to  serve  the  medical  imaging  research 
market by providing xenon polarisers to enable functional MRI of the pulmonary system.  This brings dynamic, high-
resolution, regional, image-based information to pulmonary physicians and researchers whose best alternative tool is 
spirometry, a relatively inaccurate measurement of expired breath. Current imaging technologies are not often used for 
assessing lung function, despite the revolutionary effects of MRI in other medical applications. 

Our Clinical Trials 

Our Phase III Clinical Trials are head-to-head, non-inferiority trials which are comparing our technology to an existing 
nuclear medicine technique using radioactive 133Xe and gamma cameras. The trials involve 80 patients in total and are 
being conducted at three of our closest collaborative sites, the University of Virginia Duke University (“Duke”) and the 
University  of  Cincinnati.  We  are  characterising  ventilation  in  two  sets  of  patients  being  evaluated  for  surgical 
procedures:  those  who  are  being  evaluated  for  lung  lobar  resection  surgery  and  those  being  evaluated  for  lung 
transplant. In each case their pre-operative expired vital capacity is measured through spirometry. Our technology and 
the existing nuclear medicine standard of care are used to assess the remaining post-operative vital capacities. Our 
trial has focused entirely on the pre-operative assessment and it makes no difference whether the patient is chosen for 
surgery. We are at an advanced stage in the trial and expect enrolment to conclude in the third quarter of 2019. 

Our Operations 

The Group completed the transition of manufacturing to a local certified medical device manufacturer. In 2018, we built 
and shipped five units and one upgrade. This is the largest production volume we have achieved. This included the 
transition to GMP level production for the Clinical Trial units and all units thereafter. We will continue to improve the 
production capability of our provider moving forward. 

R&D 

We  continued  to  invest  in  our  intellectual  property  portfolio  during  the  year.  Key  new  patent  filings  involving  gas 
exchange and pulmonary vascular disease were added, and an expanded and enhanced license agreement with Duke 
was achieved. 

2018 Financial Results 

Broadly speaking, our operating performance was as we expected in 2018, with revenues slightly higher than expected 
at US$2.439 million and expenses slightly lower than expected. In addition, we raised US$1M (before expenses) in 
July 2018 in a placing based on investor demand and US$4 million (before expenses) in December 2018 (a significant 
majority of the proceeds from the December 2018 placement were received by the Company in early 2019) in a placing 
designed to fund the company through our Clinical Trial enrolment.  During the period, we benefitted from the Year 2 
proceeds of the NIH SBIR Grant which we have jointly with the University of Cincinnati Children’s Hospital. Our pricing 
and margins  have  maintained  throughout  the  year.  It is  still  the case that  the  majority  of our  research  systems  are 
procured via grant mechanisms and while the outcomes are typically known with some certainty, the ultimate fiscal 
timing of these projects is difficult to predict with certainty. 

Polarean Imaging plc 
5 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Chief Executive Officer’s Statement 

continued 

2019 and Beyond 

We plan to complete enrolment of our Phase III trials in the third quarter of 2019 and look forward to the readout of both 
indications with confidence, based on the results of our Pilot Study. We will proceed with filing our NDA  and continue 
to cautiously plan to receive regulatory approval in the second half of 2020. In the meantime, we continue to collaborate 
with researchers in the US and abroad and look to expand our installed base of research systems. The exciting new 
developments  in  cardiology  and  pulmonary  vascular  disease  are  expanding  and  our  knowledge  base  about  these 
conditions is expanding. 

We  have  begun  early  discussions  with  potential  strategic  partners  in  the  pharmaceutical  industry  and  in  other 
geographic  markets  that  could  lead  to  important  developments  in  new  applications  and  uses  for  our  technology, 
expansion into new territories, and which may bring economic benefits to the Group going forward. 

Polarean is fortunate to have an outstanding collection of world-class collaborators and customers in both the US and 
Europe. Additionally, we support the “129Xe MRI Clinical Trials Consortium” and the crucial work they do in collaborative 
research, training investigators, providing infrastructure for evaluating new techniques, and multi-institution sharing of 
magnetic resonance (MR) techniques and image analysis methods. We would like to thank the National Heart Lung 
and Blood Institute for their continued support of our Small Business Innovation Research Program grant with Cincinnati 
Children’s  Hospital  Medical  Center.  In  addition,  we  have  developed  solid  working  relationships  with  MRI  systems 
manufacturers and exclusive relationships with global industrial gas suppliers, all key to our future as we scale the 
business.  

On behalf of the entire staff of Polarean Imaging, I would like to thank you for your investment in and support of the 
Group and we look forward to continuing to develop and deliver this critical life-saving and life-improving technology to 
physicians and patients everywhere. 

Richard Hullihen 
Chief Executive Officer  

26 June 2019

Polarean Imaging plc 
6 

 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

1. Introduction   

The Group comprises medical drug-device combination companies operating in the high resolution medical imaging market. The 
Group develops equipment that enables existing MRI systems to achieve an improved level of pulmonary functional imaging and 
specialises in the use of polarised Xenon gas (129Xe) as an imaging agent to visualise ventilation (the ability of air to reach the alveoli) 
and gas exchange (the ability of oxygen to diffuse through the alveolar membrane into the pulmonary vasculature) regionally down 
to the smallest airways of the lungs, the tissue barrier between the lung and the bloodstream and in the pulmonary vasculature; and 
now  also  microvascular  hemodynamics,  a  novel  diagnostic  approach.  The  Group  also  develops  and  manufactures  the  high 
performance MRI radiofrequency (RF) coils which are a required component for imaging 129Xe in the MRI system. The development 
of these coils by the Group facilitates the adoption of the Xenon technology by providing application-specific RF coils which optimise 
the imaging of 129Xe in MRI equipment. 

The Group was formed on 31 May 2017 when the Company acquired Polarean, Inc (the Subsidiary). The Subsidiary was 
formed as a result of two mergers: the first between Polarean Merger-Sub Inc. and m2m, a company that the Subsidiary had 
developed a relationship with during the course of previous research and commercialisation programmes in the US and the 
second between m2m and the Subsidiary. m2m was previously a portfolio company of Amphion Innovations plc (‘Amphion’), 
developer of medical, life science, and technology businesses, which is itself currently quoted on AIM. 

2. 

Investment Case 

Pulmonary disease currently affects hundreds of millions of people globally, including approximately 174 million people who suffer 
from Chronic Obstructive Pulmonary Disease (COPD), which is responsible for approximately 6% of all such deaths globally each 
year. In the US more than 30 million people suffer from a chronic lung disease such as COPD, which includes emphysema, chronic 
bronchitis and asthma. In addition to its significant human toll, pulmonary disease also represents an economic burden in excess of 
US$150 billion annually in the US alone. 

Every type of pulmonary disease involves some combination of ventilation and/or gas exchange impairment, yet the successful 
and cost-effective treatment of lung disease is hampered by sub-optimal methods for quantifying pulmonary ventilation and gas 
exchange.  Current  diagnostic  techniques  are  either  imprecise  (such  as  spirometry)  and/or  expose  the  patient  to  potentially 
dangerous radiation (such as x-rays, CT scans and nuclear scintigraphy). While spirometry has benefits as a screening tool, 
none of these current methods can visualise ventilation or gas exchange regionally in the smallest airways, where lung disease 
typically begins and where improvements from new pharmaceutical therapies can first be detected. 

As such, the Group operates in an area of significant unmet medical need and a number of key milestones are expected to be 
achieved by the Group in the short to medium term. The most important near-term milestone will be the successful completion of 
the FDA Phase III clinical trial in the US for the Group’s technology. The ongoing 80 patient non-inferiority trial is being conducted 
at Duke University Medical Center, the University of Virginia and The University of Cincinnati three leading US research hospitals. 
The trial has enrolled a significant majority of the 80 patients and is expected to complete enrolment by the end of the third quarter 
of 2019.  The Group will file a New Drug Application (NDA) after completion of the current Phase III trial. Upon completion of the 
Phase III trial and filing of the NDA, the Directors anticipate receiving a broad indication for use from the FDA following the FDA’s 
review period. 

The  Group’s  technology  overcomes  important  limitations  of  current  lung  diagnostic  methods,  providing  the  ability  to  visualise, 
quantify and monitor both the structure and function of the smallest airways and alveolar spaces with enhanced sensitivity and 
without harmful radiation. This provides a unique, valuable and more precise tool to help diagnose disease earlier, identify the type 
of intervention likely to benefit a patient, monitor the efficacy of treatment and  facilitate developing new therapies for pulmonary 
diseases. 

Polarean Imaging plc 
7 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

3. 

Group Structure and History 

The  Company  was  incorporated  in  England  and  Wales  on  24  October  2016  with  company  registration  number 
10442853. The Company’s registered office is 27-28 Eastcastle Street, London, W1W 8DH. 

On 31 May 2017, m2m, a company formed in the US State of Delaware on 18 February 1999, was merged into the Company.   

On 29 March 2018, the Company listed it shares on the AIM Market of the London Stock Exchange 

4. 

Information on Polarean, m2m and Strategy of Group 

4.1 Polarean, Inc. – Background 

The Subsidiary was co-founded by Dr Bastiaan Driehuys, a current Director of the Company, and John Sudol, a former director 
of the Subsidiary, in 2011. Prior to co-founding the Subsidiary, Dr Driehuys was a member of a research team at Princeton 
University in the early 1990s which was amongst the first research teams to focus on hyperpolarised gas MRI technology, in 
particular isotopically enriched Helium (3He), and developed and held key patents relating to the technology. The technology 
was acquired in 1999 by Amersham, Inc. (“Amersham”), with the goal of commercialising hyperpolarised Helium products to 
be marketed and distributed alongside Amersham’s full line of contrast agent products. Dr Driehuys led the development 
efforts for Amersham, which continued the development of these hyperpolarised Helium products throughout the early 2000s 
until GE Healthcare (“GE”) acquired Amersham in 2004. 

GE continued the research and development of hyperpolarised gas MRI after the acquisition of Amersham, focusing on 129Xe as 
a more effective substitute for 3He in visualising ventilation. GE also began to explore ways in which 129Xe could be used to image 
gas exchange within the lung in addition to ventilation. These work programmes culminated in the conduct of a Phase I/II 
clinical trial at Duke University in 2008-2009. GE also filed INDs with the FDA for both 3He and 129Xe. By 2010, after an 
investment of around US$40 million in the technology and with the regulatory path for hyperpolarised gas remaining unclear, 
GE decided to out-license the hyperpolarised gas technology and the related patent families that it had developed and/or 
maintained to the Subsidiary, due to the scale at the time and the early stage nature of the technology’s development. 

In December 2011, the Subsidiary negotiated the acquisition of all of GE’s assets related to the hyperpolarised MRI 
project,  including  an  inventory  of  polarisers  and  parts  and  the  licenses  (or outright  ownership)  of  the  related  patent 
families. 

Following the acquisition of GE’s hyperpolarisation assets, the Subsidiary focused on three key objectives: 

• 

• 

• 

building  and  selling  polarisers  to  research  users  to  generate  operating  revenue  and  to  disseminate  the 
technology to academic research institutions that generate clinical data in order to build additional interest in 
the technology; 

further  developing  the  xenon  hyperpolarisation  technology  in  order  to  meet  clinical  use  specification 
requirements; and 

liaising  with  the  FDA  in  order  to  clarify  the  FDA  regulatory  path  under  which  the  product  could  achieve 
clearance to market for clinical use. 

In July 2012, the US Congress passed the FDA Safety and Innovation Act and the Medical Gas Act, which clarified and 
simplified the path under which hyperpolarised gas MRI technology could be approved for clinical use by the FDA. 

As a result of discussions between the Group and the FDA, the Directors believe that a clearer path towards regulatory 
approval now exists. As such, following Admission the Group intends to focus on conducting the clinical studies required 
for FDA approval to market. 

Between 2012 and May 2017, the Subsidiary generated over US$3.7 million of revenue from selling polarisers to customers 
in  Canada,  Germany,  the  UK  and  the  US  for  research  use,  relating  to  both  clinical  (human)  and  pre-clinical  (animal) 
applications. In addition, the Subsidiary received additional funding of approximately US$2.5 million from Nukem and other 
Series A investors. Prior to the m2m Merger, the Subsidiary was also successful in receiving grant funding, including a US$3 
million grant awarded in April 2017 by the US National Heart, Lung and Blood Institute (NHLBI) following a competitive 
application process (for which the research will be conducted with its clinical collaborator, the Cincinnati Children’s Hospital) 
and a US$250,000 small business research loan from the North Carolina Biotech Center in March 2017, which was also 
awarded following a competitive application process.  

Polarean Imaging plc 
8 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

4.3 The Group’s Technology and Products 

The Subsidiary is a clinical-stage company and its lead product has been designated as a drug-device combination by the 
FDA.  The  Subsidiary’s  product  enables  the  visualisation  of  hyperpolarised  129Xe  (“HPX”)  via  MRI  technology  to  help 
diagnose  lung  disease  earlier,  identify  the  type  of  intervention  likely  to  benefit  a  patient  and  to  monitor  the  efficacy  of 
treatment. As a result of the FDA’s drug-device designation, the Subsidiary’s products will be approved and sold only for 
use with each other. The products are currently being used at a number of research sites on a pre-FDA clearance basis to 
facilitate the research and evaluation of lung function, to assist in making improved disease progression assessment and to 
clearly visualise the effectiveness of several therapeutics which are under development. The Group currently generates 
revenue from the sale of its 129Xe gas hyperpolarisation platform. 

Implementing the Group’s technology in a clinical setting is straightforward: prior to the MRI scan a patient breathes in 
a small amount of inert HPX to provide an extremely strong MRI signal. This transforms the MRI from a technology that 
is not applicable to the lungs into one that is able to provide multiple images of the lung structure and function in one 
10-20 second breath-hold. HPX MRI overcomes the limitations of traditional pulmonary function testing as HPX MRI: 

• 

• 

• 

is more accurate and reproducible than spirometry and other traditional pulmonary function tests, enabling the 
detection and mapping of small and localised changes in lung ventilation and gas exchange over time; 

provides regional information about lung disease without exposure to ionising radiation or radioactivity; and 

assesses ventilation and gas exchange in the smallest airways, where disease often begins. 

The Group’s technology works in conjunction with traditional MRI, transforming it into a powerful diagnostic modality for 
the lung. The Group’s approach is to take 129Xe, an inert gas, and hyperpolarise the nucleus to create an MRI signal which 
is approximately 100,000 times stronger than a conventional  MRI signal. When the MRI scan is undertaken, the HPX 
resonates at different frequencies: (i) in the bronchioles and alveoli of the lung; (ii) in the barrier tissue of the lung; and (iii) 
when dissolved in arterial blood in the pulmonary vasculature, thus providing information on ventilation (the ability of air to 
reach  the  alveoli)  and  gas  exchange  (the  ability  of  air  to  diffuse  through  the  alveolar  membrane  into  the  pulmonary 
vasculature).  As  all  pulmonary  diseases  result  from  impairments  to  the  free  flow  of  air  through  bronchioles,  or  from 
abnormal gas exchange between the lung alveoli and the pulmonary vasculature, the images that result from HPX MRI 
scans  which  have  been executed  using  the  Group’s  technology  can  aid  diagnosis,  as  the physician’s  ability  to  clearly 
identify  issues  with  ventilation  and  gas  exchange  on  a  regional  basis,  down  to  the  smallest  of  airways,  is  enhanced. 
Hyperpolarisation of the 129Xe is accomplished by placing a non-radioactive isotope of Xenon (129Xe) into a beam of circularly 
polarised laser light in the presence of very small concentration of the alkali metal Rubidium, which acts as a physical catalyst in 
the hyperpolarisation process. The result is  129Xe whose  nuclear  magnetic  spin  is  highly  aligned  but  not  chemically  or 
biologically different than unpolarised 129Xe, an inert gas. This hyperpolarised state persists for around 2 hours allowing 
ample time to administer the HPX to the patient. 

The Group’s products include: 

• 

• 

• 

• 

the 129Xe gas, blended and made under GMP at high purity, to be polarised within the polariser; 

the polariser itself, of which the latest model, the Polarean 9820 Xenon Hyperpolariser, has been designed 
to deliver up to 3 litres of HPX per hour (approximately 5-10 doses) of which each dose is to be used within 
30 minutes of its production in order to retain sufficient polarisation to create a strong image; 

the dose delivery inhalation bag, made of HPX-compatible impermeable plastic materials and a mouthpiece 
for ease of inhalation; and 

the  Polarean  2881  Polarisation  Measurement  Station,  which  provides  a  calibrated  measurement  of  the 
polarisation of hyperpolarised gas within the dose delivery inhalation bag. 

The Group currently designs and builds the polariser equipment and has relationships with GMP gas producers to 
supply the Group with high purity 129Xe. 

In order to take advantage of the Group’s current products, an MRI machine is required to be outfitted with hardware and 
software capable of operating at 129Xe frequency to detect the HPX signal. In addition, the patient will need to wear a 129Xe 
RF chest coil to allow for detecting the HPX MR signal in the lungs. Approximately 35,000 MRI machines are currently in 
use worldwide and technically many of these can be easily adapted to be used with 129Xe frequency. The Group’s products 
can  be  placed  near  the  MRI  scanner  for  ease  of  radiology  workflow  and,  following  the  m2m  Merger,  the  Group  has 
continued to explore ways to further integrate the Group’s existing technology with the coils which had previously been the 
focus of m2m. 

Polarean Imaging plc 
9 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

4.5 Location 

The Group is based at the Meridian Corporate Center, located in the Research Triangle Park area of North Carolina, which 
provides a favourable location at which to further develop the core technology and product range. The Group’s facilities consist 
of more than 4,000 square feet of combined offices, laboratory space, inventory warehouse and assembly and testing areas. 
The Group benefits from facilities that were originally purpose-built by GE for the design and manufacture of hyperpolarisation 
equipment and components, pursuant to FDA-mandated guidelines. 

Within  these  facilities  are  a  dedicated  research  and  development  laboratory  equipped  with  3-phase  power,  central 
compressed  air,  specialty  gas  handling  and  distribution  and  separate  heating,  ventilation  and  air  conditioning.  The 
laboratory area also includes optical cell production equipment capable of simultaneous processing of four optical cells 
for Xenon applications. The laboratory is designed for safe operation of class 4 lasers and is equipped with laser power 
and spectral testing apparatus. 

The Group also maintains a dedicated polariser test bed that is used for product development and a dedicated NMR 
system  capable  of  delivering  available  electromagnetic  field  strength,  utilised  for  calibrating  absolute  polarisation 
measurements of hyperpolarised gas samples. 

4.6 The Regulatory Environment 

At present, prior to the receipt of any approvals for clinical use, the Group sells its polarisers and disposables for research 
use only to academic medical centres with their research being subject to oversight by their respective institutional review 
boards and conducted under IND from the FDA or equivalent regulatory body. 

The Group has held regular meetings with the FDA to develop a path towards approval for clinical use and the FDA has 
indicated its willingness to accept a very broad indication for use for the Group’s technology – for the evaluation of pulmonary 
function  –  as  opposed  to  its  use  being  limited  to  any  particular  pulmonary  disease  or  condition.  The  FDA  has  reviewed 
proposals for the Group’s Phase III clinical trials and has provided clearance for the trials to take place. The Phase III trials 
include a total of 80 patients and the FDA has indicated that it will also accept existing literature-based data in fulfilment of 
certain  safety  and  toxicology  requirements.  The  Directors  believe  that  this  broad  indication  and  limited  clinical  trial  size 
provides the Group with a sizeable, addressable market at a modest clinical trial cost. 

4.7 The Group’s Customers 

The Group’s existing customer base already comprises some of the world’s luminary medical imaging research institutions. 
Indeed,  there  are  currently  twelve  research  institutions  worldwide  utilising  the  Group’s  system  and  products,  including 
Cincinnati Children’s Hospital, the University of Virginia, University of Wisconsin – Madison and Duke University in the US, 
Robarts Research Institute and Hospital for Sick Children (SickKids) in Canada, the University of Oxford and the University of 
Nottingham in the UK and the Fraunhofer Institute for Toxicology and Experimental Medicine in Germany. At the date of this 
report, there are currently 24 Xenon Hyperpolariser units installed at these and several other leading research hospitals and 
the Group anticipates selling further units for research purposes during the course of the Phase III clinical trial. 

4.8 The Group’s Suppliers 

The Group has entered into Master Service Agreements with two CROs in relation to the Phase III trial. Pharma Start LLC, 
doing business as Firma Clinical Research, has been engaged to project manage the trial and will oversee the recruitment 
of patients for the trial. In addition, Icon Clinical Research Limited will assist with the medical imaging aspects of the trial.  

The Group has a long-standing relationship with its strategic investor Nukem Isotopes GmbH, a leading global supplier 
of 129Xe, the isotope of Xenon which is provided to the various gas blenders that in turn supply gas to the Group. It has 
a supply agreement with Nukem for 129Xe. 

In December 2017 the Group signed a letter of intent (“LoI”) with Linde Electronics and Speciality Gases, a division of Linde 
Gas North America LLC (“Linde”), in relation to a potential product supply agreement. Under the terms of the LoI, the Group 
and Linde have agreed to negotiate, prepare and sign a product supply agreement for the supply of industrial gas to the 
Group, subject to all required licenses and approvals being obtained by the parties. This agreement contains provision for the 
supply of bulk Xe to be enriched to 129Xe, and for the blending, packaging, and distribution of its drug product under GMP. 

4.9 Current Trading and Prospects 

Trading of the Group since IPO continues to be in line with the Directors’ expectations. The potential of the Group’s 
technology enables the Directors to view the future with confidence ahead of the completion of the Phase III clinical 
trials and the exploitation of the addressable markets for the Group’s technology. 

Polarean Imaging plc 
10 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

4.10 Growth Strategy 

The Group estimates that in the short term it will generate additional revenue from the sale of hyperpolarisers to global 
research  institutions  and  the  Directors  believe  that  the  market  for  polarisers  will  grow  as  the  technology  gains  wider 
acceptance as a tool for studying lung disease and for monitoring the effectiveness of therapeutics. At present, a number of 
major pharmaceutical companies are working with universities that are well known to the Group, regarding the use of HPX 
MRI technology to help guide clinical trials of developmental pharmaceutical products which is raising awareness of the 
Group’s technology and product range. 

The FDA have accepted the Group’s Phase III clinical trial design and upon completion of the Phase III trial and subsequent 
FDA approval, the Group will adopt a traditional market entry strategy of building market awareness for its technology through 
key opinion leaders and a direct sales force to reach the key decision makers within its initial target market of large academic 
medical centres. In implementing this strategy, the Group benefits from  approximately 1000 journal articles on the use of 
hyperpolarised gas MRI that are currently published in peer-reviewed journals. Over time, as more research centres purchase 
the Group’s equipment and begin clinical studies, an increasing number of peer reviewed scientific articles are likely to be 
published, further enhancing the Group’s credibility and raising awareness of the Group’s technology. The Group also intends 
to continue patenting and in-licensing hyperpolarised gas technology IP to protect its current position. 

Following completion of the Phase III trial and upon receipt of FDA clearance to market the technology, the Group’s initial 
sales targets will be the radiology and pulmonary medicine departments of top academic hospital organisations in the US, 
who are opinion leaders in the use of new diagnostic technologies and their application in a clinical setting. 

Subsequently, the Group will seek to expand its sales and marketing teams. Because of the specialty nature of the Group’s 
products in the pulmonary specialist market, which is concentrated in approximately 1,000 medical centres, the Directors 
believe that a small specialty sales force can be deployed effectively at reasonable cost. 

The Group may also choose to partner with companies that offer complementary products. 

Furthermore, the Directors believe that the Group’s products will benefit a number of clinical applications. While the Group’s HPX 
MRI technology provides more specific information than currently available using existing lung diagnostic procedures (especially 
spirometry), the Group will focus its use on specific clinical conditions where the high accuracy of HPX MRI and greater cost are 
justified. The Directors do not believe that HPX MRI will replace low-cost spirometry as a general screening tool but believe that 
it  should  add  value  in  more  demanding  clinical  applications  where  HPX  MRI  addresses  unmet  diagnostic  needs.  These 
applications could include, but are not limited to, the following: 

the monitoring of COPD therapy, especially for the most severe cases; 
the management of cystic fibrosis exacerbations; 

• 
• 
•  a more efficient diagnosis of dyspnoea and the chronic cough; 
•  providing guidance for radiation therapy planning of lung cancer treatment; 
•  providing guidance for interventional pulmonology procedures including ablation and the placement of valves and 

stents; 

•  surgical procedure planning for lung transplant and volume reduction surgery; 
•  diagnosis of IPF and monitoring of IPF therapy; and 
•  diagnosis of pulmonary vascular disease (PVD) including pulmonary arterial hypertension (PAH) and monitoring of 

therapy. 

The Directors have begun to develop relationships with a range of strategic partners and will evaluate opportunities 
which will enable the Group to address its target markets globally, either alone or in collaboration with a partner. 

5. 

Intellectual Property (“IP”) 

The  Group’s  technology  has  been  developed  in  four  areas:  (i)  hyperpolarising  gas;  (ii)  assuring  the  quality  of  the 
hyperpolarised gas; (iii) using the polarised gas in MRI applications; and (iv) developing and producing specialised RF 
coils to improve signal-to-noise ratios (“SNR”). GE had put a comprehensive patent policy in place to protect its technology 
from potential competitors. The Group is now the sole owner of this IP portfolio, which is based on 22 patent families, and 
when combined with the 7 patents that were previously owned by m2m, that were transferred to the Group following the 
m2m Merger, the Group’s portfolio covers four broad types of patents: 

• 

imaging methods – these cover the imaging of a subject, or patient, who has inhaled a hyperpolarised noble gas and the 
functionality of the gas as a contrast agent. Newly licensed technology from Duke University extends the protection over 
these patents through to the early 2030s; 

Polarean Imaging plc 
11 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

•  hyperpolarisation  methods  –  these  are  Polarimetry  patents  covering  the  methods  by  which  noble  gases  are 
polarised and the methods by which the resulting polarised gas is isolated and delivered to patients. The latest 
of these patents expire in the early 2020s; 

•  hyperpolarisation  equipment  –  these  patents  cover  the  multiple  preferred  mechanical  design  and  automation 

elements of hyperpolarised equipment; and 

•  RF coil patents – these patents cover the use of cryogenics to improve RF coils SNR and image quality and may 
play an important part in the next generation of applications such as neurological, cardiac and oncology imaging. 

Polarean is committed to proactively developing further IP, both internally and through licensing arrangements with third 
parties, as part of the Group’s overall growth strategy. The third parties are likely to include the Group’s key collaborative 
academic sites, such as Duke University, that are seeking to develop emerging applications and technologies. Because of 
the Group’s extensive patent portfolio and leading market position, the Directors believe the Group is an attractive licensing 
partner  for  academic  research  institutions  that  are  interested  in  out-licensing  such  IP.  One  such  patent  application 
(US15/120013), which is currently pending, relates to improving the overall efficiency of the hyperpolarisation process. 
This patent has also been exclusively licensed to the Group by Duke University. The Directors believe that this patent, now 
having been prosecuted successfully to issuance in a number of geographic jurisdications worldwide, would enable the 
Group to protect methods for increasing the level of hyperpolarisation significantly, which could improve the competitive 
economics of the Group’s products.  

6. 

Principal risks and uncertainties 

The principal risks and uncertainties facing the Group are detailed below:  

Early stage of operations 

The Group’s operations are at an early stage of development and there can be no guarantee that the Group will be able to, 
or that it will be commercially advantageous for the Group to, develop its proprietary technology. Further, the Group currently 
has no positive operating cash flow and its ultimate success will depend on the Directors’ ability to implement the Group’s 
strategy, generate cash flow and access capital markets.  

Principal mitigation  
The Group has successfully advanced the 129Xe technology for several years, including selling polarisers for the research 
market.   The Group has been able to access capital required to continue to advance the technology.   

Regulatory approvals and compliance 

The Group will need to obtain various regulatory approvals (including FDA and EMA approvals) and otherwise comply with 
extensive  regulations  regarding  safety,  quality  and  efficacy  standards  in  order  to  market  its  future  products.  These 
regulations, including the time required for regulatory review, vary from country to country and can be lengthy, expensive 
and uncertain.  

Principal mitigation  
The Group utilises external specialists in regulatory affairs who consult with other experts to ensure that internal control 
processes  and  clinical  trial  designs  meet  current  regulatory  requirements.    The  Group  also  engages  directly  with 
regulatory authorities when appropriate. 

Future funding requirements 

The Group will need to raise additional funding or enter into a strategic partnership with industry partners to undertake 
work beyond that being funded by the Placing and Subscription. There is no certainty that this will be possible at all or 
on acceptable terms.  

Principal mitigation  
The  Group  successfully  engaged  with  investors  to  generate  significant  cash  resources  to  date.    The  Group’s 
Management Team expects that continued access to capital markets, or other access to capital, will be required to 
support the Group through regulatory approval and initial commercialisation efforts in the United States.  See Going 
Concern discussion above. 

Polarean Imaging plc 
12 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

Dependence on key personnel 

The success of the Group, in common with other businesses of a similar size, will be highly dependent on the expertise and 
experience of the Directors and key employees. However, the retention of such key personnel cannot be guaranteed. Should 
key personnel leave the Group’s business, prospects, financial condition or results of operations may be materially adversely 
affected. 

Principal mitigation  
The  Group’s  recruitment  processes  are  designed  to  identify  and  attract  the  best  candidates  for  specific  roles.    The 
Group aims to provide competitive rewards and incentives to staff and directors.   

Intellectual property and proprietary technology 

No assurance can be given that any current or future patent applications will result in granted patents, that the scope 
of any patent protection will exclude competitors or provide competitive advantages to the Group, that any of the Group’s 
patents will be held valid if challenged or that third parties will not claim rights in or ownership of the patents and other 
proprietary rights held by the Group. 

Principal mitigation  
The Group has a long-standing track record of IP generation and successful applications and have a long-standing 
relationship with our patent attorney who has a deep understanding of our technology.  The Group actively manages 
its IP, engaging with specialists to apply for and defend IP rights in appropriate territories. 

Technology and products 

The Group is a manufacturer and service provider for noble gas 29Xe devices and ancillary instruments with a special focus 
on pulmonary imaging. The development and commercialisation of its proprietary technology and future products, which are 
in early stages of development, will require multiple series of clinical trials and there is a risk that safety and efficacy issues 
may arise when the products are tested. There is also a risk that there will be delays to the development of the products or 
that  unforeseen  technical  problems  arise  as  the  Group’s  technology  becomes  increasingly  automated.  These  risks  are 
common to all new medical products and there is also a risk that the clinical trials may not be successful. 

Principal mitigation  
The Group has a depth of knowledge and experience in the area of medical devices development for the high resolution 
medical imaging market.  The Group also utilises external experts to supplement their knowledge in critical areas such as 
safety, manufacturing and software development.   

Research and development risk 

The Group will be operating in the life sciences and medical device development sector and will look to exploit opportunities 
within that sector. The Group will therefore be involved in complex scientific research and industry experience indicates that 
there may be a very high incidence of delay or failure to produce results. The Group may not be able to develop new products 
or to identify specific market needs that can be addressed by technology solutions developed by the Group.  

Principal mitigation 
The Group has a depth of knowledge and experience in the area of medical devices development for the high resolution 
medical imaging market.  The Group also utilises external experts to supplement their knowledge in critical areas such as 
conducting clinical trials and regulatory affairs.   

Reliance on third parties 

The business model for the Group anticipates that it will have limited internal resources over the next few years and that it will 
use third party providers wherever possible to conduct the research, development, registration, manufacture, marketing and 
sales of its proposed products. The commercial success of the Group’s products will depend upon the performance of these 
third parties.  

Principal mitigation  
The  Group  seeks  experts  in  the  areas  where  it  utilises  outsourcing.    Wherever  possible,  the  Group  seeks  to  have 
duplicate suppliers to lessen the reliance on a particular vendor.  

Polarean Imaging plc 
13 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Strategic Report 

continued 

Manufacturing 

There  can  be  no  assurance  that  the  Group’s  proposed  products  will  be  capable  of  being  manufactured  in  commercial 
quantities,  in  compliance  with  regulatory  requirements  and  at  an  acceptable  cost.  The  Group  intends  to  outsource  the 
manufacture  of  the  raw  materials  and  finished  products  required  in  connection  with  the  research,  development  and 
commercial manufacture of its proposed products and, as such, will be wholly dependent upon third parties for the provision 
of adequate facilities and raw  material supplies.  129Xe, the specific isotope of Xenon  which is the active ingredient in the 
Group’s drug-device product, is available from a limited number of suppliers and there can be no assurance that adequate 
supplies of this material at acceptable cost can be obtained. In addition, where the Group is dependent upon third parties for 
manufacture, its ability to procure the manufacture of the drug-device in a manner which complies with regulatory requirements 
may be constrained, and its ability to develop and deliver such products on a timely and competitive basis may be adversely 
affected. 

Principal mitigation  
The Group has designed the manufacturing process to be scalable and internal experts that train the outside vendors.  
The Group has established relationships with two 129Xe suppliers to mitigate the risk that 129Xe supply will be a limitation 
to the development and commercialization of its products. 

Product development timelines 

Product development timelines are at risk of delay, particularly since it is not always possible to predict the rate of patient 
recruitment into clinical trials. There is a risk therefore that product development could take longer than presently expected by 
the Directors. If such delays occur the Group may require further working capital. The Directors shall seek to minimise the risk 
of delays by careful management of projects. 

Principal mitigation  
The  Group  utilizes  contract  research  organisations  that  are  experts  in  recruiting  and  conducting  clinical  trials.    The 
Group contracted with an additional clinical site to increase the enrollment rate for the clinical trial. 

General legal and regulatory issues 

The Group’s operations are subject to laws, regulatory restrictions and certain governmental directives, recommendations and 
guidelines  relating  to,  amongst  other  things,  occupational  safety,  laboratory  practice,  the  use  and  handling  of  hazardous 
materials, prevention of illness and injury, environmental protection and animal and human testing. There can be no assurance 
that  future  legislation  will  not  impose  further  government  regulation,  which  may  adversely  affect  the  business  or  financial 
condition of the Group. Furthermore, as the Group already has some exposure to the UK market, there is a risk that possible 
changes resulting from the Brexit negotiations could lead to additional barriers to trade and regulatory divergence which could 
adversely affect the Group 

Principal mitigation   
The Group consults experts for advice in areas such as occupational safety, laboratory practice and human testing.  
The Group’s initial focus is on the US market, so Brexit negotiations should not impact the development pathway for 
the Group’s products.  The Group will continue to monitor the Brexit situation and assess the impact on the Group’s 
ability to access capital in the UK.  

Healthcare pricing environment 

In common with other healthcare products companies, the ability of the Group and any of its licensees or collaborators to 
market its products successfully depends in part on the extent to which reimbursement for the cost of such products and 
related treatment will be available from government health administration authorities, private health coverage insurers and 
other organisations.  

Principal mitigation  
The Group has contracted with an expert in the field of reimbursement for healthcare products in the US to determine 
the best strategy for accessing adequate reimbursement for its products.   

Richard Morgan  
Non-Executive Chairman 

26 June 2019 

Polarean Imaging plc 
14 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Directors’ Report   

The Directors present their report on the affairs of Polarean Imaging plc (the “Company”) and its subsidiaries, referred 
to as the Group, together with the audited Financial Statements and Independent Auditors’ Report for the year ended 
31 December 2018. 

Principal activities 

The main activity of the Group is a drug device manufacturer and service provider for noble gas polarizer devices, its 
proprietary 129Xe drug and ancillary instruments with a special focus on pulmonary imaging.  

Results and dividends 

During the year ended 31 December 2018 the Group recorded a loss after tax of US$5,454,659 (2017: US$3,957,821) 
and a net cash outflow from operating activities of US$4,676,346 (2017: US$2,615,901). 

The Directors do not recommend the payment of a dividend (2017: US $nil). 

Going concern 

In considering the appropriateness of this basis of preparation, the Directors have reviewed the Group’s working capital 
forecasts  for  a  minimum  of  12  months  from  the  date  of  the  approval  of  this  financial  information.    Based  on  their 
consideration the Directors have reasonable expectation that the Group has adequate resources to continue for the 
foreseeable future and that carrying values of intangible assets are supported.  Thus, they continue to adopt the going 
concern basis of accounting in preparing this financial information. 

Future developments 

The Company’s future developments are outlined in the Strategic Report on page 11. 

Research design & development 

Research and development is performed by employees of the company.  The Group is committed to increasing 
its R&D budget to meet anticipated market demands for additional technology. In addition, the company also in -
licenses  technology  from  collaborative  academic  institutions.  Details  of  R&D  carried  out  during  the  year  are 
contained in the Strategic Report. 

Financial risk management 

Financial  risk  management  policies  and  objectives  for  capital  management  are  outlined  in  the  principal  risks  and 
uncertainties section of the strategic report on pages 12 to 14 and in note 25 to the financial statements. 

Directors’ indemnities  

The Group has made qualifying third-party indemnity provisions for the benefit of its Directors, which were made during 
the year and remain in force at the date of this report. 

Events after the reporting period 

Details of significant events since the reporting period are contained in note 28 of the financial statements. 

Polarean Imaging plc 
15 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Directors’ emoluments 

2018 

Executive Directors  

Bastiaan Driehuys (Note A) 

Richard Hullihen (Note B) 

Kenneth West (Note C) 

Non-Executive Directors 

Richard Morgan (Note A) 

Jonathan Allis (Note A) 

Robert Bertoldi (Note A) 

Juergen Laucht (Note A) 

Total 

2017 

Executive directors 

Bastiaan Driehuys 

Richard Hullihen (Note B) 

Kenneth West (Note C) 

Non-Executive Directors 

Richard Morgan 

Jonathan Allis 

Robert Bertoldi  

Juergen Laucht 

Total 

 Directors’ Report 

continued 

Salary, Fees & 
Bonus 

Benefits 

Share-Based 
Payments 

US$ 

US$ 

US$  

37,500 

269,000 

225,000 

86,250 

33,750 

41,250 

41,250 

734,000 

- 

- 

- 

- 

- 

- 

- 

- 

9,780 

39,082 

37,098 

9,780 

9,780 

9,780 

9,780 

125,080 

859,080 

Total 

US$ 

47,280 

308,082 

262,098 

96,030 

43,530 

51,030 

51,030 

Salary, Fees & 
Bonus 

Benefits 

Share-Based 
Payments 

US$ 

US$ 

US$  

- 

155,714 

121,254 

- 

8,059 

5,727 

- 

- 

- 

- 

- 

- 

- 

- 

276,968 

13,786 

- 

- 

- 

- 

- 

- 

- 

- 

Total 

US$ 

- 

163,773 

126,981 

- 

- 

- 

- 

290,754 

Note A: The Board agreed to a 100% salary deferral in 2018. These amounts were paid in 2019. 
Note  B:  Richard  Hullihen  agreed  to  a  salary  deferral  in  2018  and  2017.  The  amounts  included  in  salaries  are 
US$117,437 and US$51,547, respectively. 
Note C: Kenneth West agreed to a salary deferral in 2018 and 2017. The amounts included in salaries are US$93,750 
and US$46,392, respectively. 

Directors’ interests 

The  Directors  who  held  office  at  31  December  2018  had  the  following  direct  interest  in  the  ordinary  shares  of  the 
Company at 31 December 2018. 

Directors’ beneficial interests in shares of the Company: 

Richard Morgan 

Richard Hullihen  

Robert Bertoldi 

Kenneth West 

Bastiaan Driehuys 

2018  
Number 
419,018 

2,137,354 

93,333 

475,594 

12,267,503 

2018 
% 
0.4 

2.1 

0.1 

0.5 

12.2 

2017 
Number 

- 

1,540,211 

- 

216,085 

12,007,994 

2017 
% 

- 

3.18 

- 

0.45 

24.77 

Polarean Imaging plc 
16 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Directors’ Report 

continued 
On  16  February  2018  the  Company  sub-divided  its  share  capital  on  the  basis  of  26.71999:1.    The  number  of 
Ordinary shares in issue in the Company at 31 December 2017 reflects the sub-division.  

The shareholdings noted above include those shares held by connected persons of the individual director.  

Directors’ beneficial interests in options to subscribe for additional shares of the Company: 

Richard Morgan 

Richard Hullihen  

Robert Bertoldi 

Kenneth West 

Bastiaan Driehuys 

Juergen Laucht 

2018  
Number 

534,400 

2,135,440 

534,400 

1,913,218 

1,336,000 

534,400 

2017 
Number 
- 

- 

- 

267,200 

801,600 
- 

On 20 April 2018, the Company issued 10,403,600 Options to certain directors, persons discharging managerial 
responsibilities  (“PDMR”)  and  employees.  The  exercise  price  for  the  Options  is  £0.15  being  the  price  at  which 
Polarean’s Ordinary Shares were placed at Admission. The Options will vest in equal portions on an annual basis 
on the anniversary of Admission, over a four-year period from the date of Admission. The options term expires on 
29 March 2028. 

The following directors were a part of the grant of PDMR options were: 

•  Richard Morgan was granted 534,400 options; 
•  Richard Hullihen was granted 2,135,440 options; 
•  Robert Bertoldi was granted 534,400 options; 
•  Kenneth West was granted 1,646,018 options; 
•  Bastiaan Driehuys was granted 534,400 options;  
Juergen Laucht was granted 534,400 options; and 
• 
Jonathan Allis was granted 534,400 under a separate option grant. 
• 

Kenneth West’s pre-2018 options have an exercise price of US$0.0337. They were issued on 16 December 2015 
and expire on 16 December 2025.  400,800 of Bastiaan Driehuys’ options with an exercise price of  US$0.00412 
were issued on 15 December 2014 and expire on 15 December 2024 and 400,800 options with an exercise price 
of US$0.0337 were issued on 16 December 2015 and expire on 16 December 2025. 

Directors’ beneficial interests in warrants to subscribe for additional shares of the Company:  

Richard Morgan 

Robert Bertoldi 

Bastiaan Driehuys 

2018 
Number 

- 

- 

148,456 

2017 
Number 

523,659 

523,659 

148,456 

The  warrants  issued  to  Richard  Morgan  and  Robert  Bertoldi  are  part  of  the  Amphion  Warrants.  They  ha d  an 
exercise price of £0.009. The warrants expired on 31 May 2018 as the Company did not raise a minimum of $5 
million at £0.25 on or before 31 May 2018. The warrants issued to Bastiaan Driehuys have an exercise price of 
US$0.00037. The warrant holdings noted above include those shares held by connected persons of the i ndividual 
director. 

Polarean Imaging plc 
17 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Directors’ Report 

continued 

The options and warrants holdings noted above include those shares held by connected persons of the individual 
director. 

Common, Options and Warrant Shares: 

(On a fully-diluted 
basis) 

Richard Morgan  
Richard Hullihen  
Kenneth West  
Bastiaan Driehuys  
Robert Bertoldi  

Number of shares 
at 31 December 
2018 
419,018 
2,137,354 
475,594 
12,267,503 
93,333 

% held at 31 
December 2018 
0.4 
2.1 
0.5 
12.2 
0.1 

Number of shares at 20 
June 2019 
419,018 
2,137,354 
475,594 
12,267,503 
93,333 

% held at 20 
June 2019 
0.4 
2.1 
0.5 
12.2 
0.1 

Note: February 2018, the Company declared a share sub-division of 26.72:1. 

Share option schemes 

In order to provide incentive for the management and key employees of the Group, the  Company awards stock 
options. The Directors defined a new plan in 2018 and implemented it. The existing options granted prior to the 
merger were converted to options in Polarean Imaging, Plc. 

Substantial Shareholders 

As well as the Directors’ interests reported above, the following interests of 3.0% and above as at the date of this report 
were as follows at 31 December 2018 (on a fully-diluted basis):  

Amphion Innovations plc 

Bastiaan Driehuys 

NUKEM Isotopes Imaging GmbH 

W.B. Nominees Limited 

Amati Global Investors 

John Sudol 

David & Monique Newlands 

Number of shares, options or warrants  % held 
18.2 

18,372,524 

12,267,503 

11,234,208 

8,736,697 

8,571,429 

6,206,121 

12.2 

11.2 

8.7 

8.5 

6.2 

3,052,000 

3.03 

Note: February 2018, the Company declared a share sub-division of 26.72:1. 

Corporate Responsibility 

The Board recognises its employment, environmental and health and safety responsibilities. It devotes appropriate 
resources  towards  monitoring  and  improving  compliance  with  existing  standards.  The  Executive  Director s  are 
responsible  for  these  areas  at  Board  level,  ensuring  that  the  Group’s  policies  are  upheld  and  providing  the 
necessary resources. 

Employees 

The  Group  is  committed  to  achieving  equal  opportunities  and  to  complying  with  relevant  anti -discrimination 
legislation. It is established Group policy to offer employees and job applicants the opportunity to benefit from fair 
employment, without regard to their sex, sexual orientation, marital status, race, religion or belief, age or disability. 
Employees are encouraged to train and develop their careers. 

The Group has continued its policy of informing all employees of matters of concern to them as employees, both 
in  their  immediate  work  situation  and  in  the  wider  context  of  the  Group’s  well -being.  Communication  with 
employees  is  affected  through  the  Board,  the  Group’s  management  briefings  structure,  formal  and  informal 
meetings and through the Group’s information systems. 

Polarean Imaging plc 
18 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Directors’ Report 

continued 

The  Directors  are  responsible  for  preparing  the  Strategic  Report,  the  Directors’  Report  and  the  Financial 
Statements in accordance with applicable law and regulations.  

Company law requires the directors to prepare financial statements for each  financial year. Under that law the 
directors have elected to prepare the financial statements in accordance with International Financial Reporting 
Standards (IFRSs’) as adopted by the EU and applicable law. 

Under company law the directors must not approve the financial statements unless they are satisfied that they 
give a true and fair view of the state of affairs of the Company and the Group and of the profit or loss of the Group 
for that period. In preparing these financial statements, the directors are  required to: 

select suitable accounting policies and then apply them consistently; 

• 
•  make judgements and accounting estimates that are reasonable and prudent; 
• 

state whether applicable accounting standards have been followed, subject to any material departur es 
disclosed and explained in the financial statements;  
prepare the financial statements on the going concern basis unless it is inappropriate to presume that 
the Group will continue in business. 

• 

The directors are responsible for keeping adequate accounting records that are sufficient to show and explain the 
Group's transactions and disclose with reasonable accuracy at any time the financial position of the  Group and 
enable  them  to  ensure  that  the  financial  statements  comply  with  the  Companies  Act  2006.  T hey  are  also 
responsible for safeguarding  the  assets  of  the  Group  and  hence  for taking  reasonable  steps  for the prevention 
and detection of fraud and other irregularities. 

They are further responsible for ensuring that the Strategic Report and the Directo rs’ Report and other information 
included  in  the  Annual  Report  and  Financial  Statements  is  prepared  in  accordance  with  applicable  law  in  the 
United Kingdom. 

The maintenance and integrity of the Polarean Imaging plc web site is the responsibility of the di rectors; the work 
carried  out  by  the  auditors  does  not  involve  the  consideration  of  these  matters  and,  accordingly,  the  auditors 
accept no responsibility for any changes that may have occurred in the accounts since they were initially presented 
on the website. Legislation in the United Kingdom governing the preparation and dissemination of the accounts 
and the other information included in annual reports may differ from legislation in other jurisdictions.  

Auditors 

Each of the persons who are directors at the time when this Directors' report is approved has confirmed that:  

• 

• 

so far as that director is aware, there is no relevant audit information of which the Group and the Group's 
auditor is unaware; and 
that director has taken all the steps that ought to have been taken as a director in order to be aware of 
any relevant audit information and to establish that the Company and the Group's auditor is aware of 
that information. 

Crowe  U.K.  LLP  has  expressed  its  willingness  to  continue  in  office  and  a  resolution  to  re  appoint  the  firm  as 
Auditor and authorising the Directors to set their remuneration will be proposed at the forthcoming Annual General 
Meeting. 

Richard Morgan  
Non-Executive Chairman 

26 June 2019 

Polarean Imaging plc 
19 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Corporate Governance Report  

Corporate Governance Statement for the year ended 31 December 2018  

As Chairman of the Board of Directors of Polarean Imaging Plc (Polarean, or the Company/Group as the context 
requires), it is my responsibility to ensure that Polarean has both sound corporate governance and an effective 
Board. As Chairman of the Company,  my responsibilities include leading the Board effectively, overseeing the 
Company’s corporate governance model, communicating with shareholders, and ensuring that good information 
flows freely between the Executive and Non-Executives Directors in a timely manner. My leadership of the Board 
is undertaken in a manner which ensures that the Board retains integrity and effectiveness and includes creating 
the  right  Board  dynamic  and  ensuring  that  all  important  matters,  in  particular  strategic  decisions,  receive 
adequate time and attention at Board meetings. 

It is the Board’s job to ensure that Polarean is managed for the long-term benefit of all shareholders, with effective 
and efficient decision-making. Corporate governance is an important part of that role, reducing risk and adding 
value to our business. 

The  Directors  of  Polarean  recognise  the  value  of  good  corporate  governance  in  every  part  of  its  business.  As 
Polarean is an AIM listed company, it is required to adopt a recognised corporate governance code and disclose 
how  it  complies  with  that  code  and,  to  the  extent  Polarean  departs  from  the  corporate  governance  provisions 
outlined by  that code, it must explain its reasons for doing so.  The Directors have adopted the requirements of 
the Quoted Companies Alliance's Corporate Governance Code for Small and Mid -Size Quoted Companies (the 
"QCA Code"), to the extent that they consider it appropriate having regard to the Company's size, board structure, 
stage of development and resources. The Board considers that compliance with the QCA Code will enable us to 
serve the interests of all our key stakeholders, including our shareholders, and will promote the maintenance and 
creation  of  long-term  value  in  the  Company.  This  report  describes  our  approach  to  governance,  including 
information on relevant policies, practices and the operation of the Board and its Committees. Additional detail on 
how the company has applied the QCA code is also provided in the corporate governance section of our website 
http://www.polarean-ir.com/content/investors/governance.asp.  Any areas of non-compliance with the QCA Code 
are also explained. 

Polarean seeks to constantly improve its corporate governance practices.  Prior to the Company listing in March 
2018, the Company implemented certain governance related measures including the formation of the Company’s 
Audit and Remuneration Committees, and the adoption of a Share Dealing Code. 

Strategy, Risk Management and Responsibility 

A description of the Company’s business model and strategy can be found on pages 7-14 in the Strategic Report, 
and the key challenges in their execution can be found on pages 12-14 under “Principal Risks and Uncertainties”.  

The  Board  is  responsible  for  the  monitoring  of  financial  performance  against  budget  and  forecast  and  the 
formulation  of  the  Group’s  risk  appetite  including  the  identification,  assessment  and  monitoring  of  Polarean’s 
principal risks. The Board recognises the need for an effective and well-defined risk management process and it 
oversees and regularly reviews the current risk management and internal control mechanisms.   

The Board has overall responsibility for identifying, monitoring and reviewing the Company’s risks, and assessing 
the systems of external control for effectiveness. The Executive Directors report any new or changed risks, and 
any changes in risk management/control to the Board. The Board discusses all business matters having regard 
to the risks for the Group and to the extent that risks inherent in a particular activity are considered significant, 
appropriate  action  is  taken  and  steps  taken  to  mitigate  the  issue.  The  overall  objective  of  the  Board  is  to  set 
policies that seek to reduce risk as far as possible without unduly affecting the Company’s competitiveness and 
flexibility.  

The Board is satisfied that the procedures in place meet the particular needs  of the Group in managing the risks 
to which it is exposed. The Board is satisfied with the effectiveness of the system of internal controls, but by their 
very nature, these procedures can provide reasonable, not absolute, assurance against material missta tement or 
loss. The Board has delegated responsibility to the Audit Committee for ensuring that the Company’s management 
reviews, monitors and reports on the integrity of the consolidated financial statements of the Company and related 
financial information. The Audit Committee will maintain effective working relationships with the Board of Directors  
and executive management, and the external auditors and will monitor the independence and effectiveness of the 
auditors and the audit. The Company has strict segregation of duties and authority controls which are reviewed 
annually by the auditors whom report their findings to the Audit Committee. 

The  Board  has  reviewed  the  need  for  an  internal  audit  function  and  has  decided  that,  given  the  nature  of  the 
Group’s business and assets and the overall size of the Group, the systems and procedures currently employed 
provide  sufficient  assurance  that  a  sound  system  of  internal  controls  are  in  place,  which  safeguards  the 
shareholders’ investment and the Group’s assets. An internal audit function is therefore considered unnecessary. 
However, the Board will continue to monitor the need for this function. 

Polarean Imaging plc 
20 

 
 
 
 
 
 
 
 
 
 
 
Corporate Governance Report  

Continued 

The  Board  is responsible  for  the  Group’s system  of internal control  and  for reviewing  its effectiveness.  Such a 
system is designed to manage rather than eliminate risk of failure to achieve the business objectives and can only 
provide  reasonable  and not absolute  assurance against material misstatement or  loss.  The  Company’s  current 
system of internal financial control comprises those controls established to provide reasonable assurance of:  

The safeguarding of assets against unauthorised use or disposal; and 

• 
•  The maintenance of proper accounting records and the reliability of financial information used within the business 

and for publication 

The key procedures of internal financial control of the Group are as follows: 

•  The Board reviews and approves budgets and monitors performance against those budgets on a monthly basis.  
•  The Group has clearly defined reporting and authorisation procedures relating to the key financial areas. 

The Board 

The Group is run by the Board of Directors, which comprises  three Executive Directors and four Non-Executive 
Directors. As the business grows and becomes more complex it is anticipated that the  Board will be added to. In 
addition, the Group has a Chief Financial Officer, Charles Osborne and a Company Secretary, Stephen Austin.  

The Board meets regularly and is responsible for the Group’s corporate strategy, monitoring financial performance, 
approval of capital expenditure, treasury and risk management policies. Board papers are sent out to all Directors 
in  advance  of  each  Board  meeting  including  management  accounts  and  accompanying  reports  from  those 
responsible. 

At the date of this Report, the Board has seven members, whose roles are set out below: 

Director’s Name 

Richard Morgan 

Position(s) 
Non-Executive Chairman, Chairman of the Remuneration Committee & member of 
the Audit Committee 

Richard Hullihen 

Executive Director – Chief Executive Officer 

Kenneth West 

Executive Director – Chief Operating Officer 

Bastiaan Driehuys 

Executive Director – Chief Technology Officer & member of Remuneration 
Committee  

Robert Bertoldi 

Non-Executive Director & Chairman of the Audit Committee, 

Jonathan Allis 

Independent Non-Executive Director 

Juergen Laucht 

Non-Executive Director & member of Remuneration and Audit Committees 

The  biographical  details  of  the  Directors  of  the  Company  are  set  out  on  the  Company’s  websi te: 
http://www.polarean-ir.com/content/investors/board.asp 

The Directors believe that the Board, as a whole, has a broad range of commercial and professional skills, enabling 
it to discharge its duties and  responsibilities effectively  and that the  Non-Executive  Directors, together, have a 
sufficient range of experience and skills to enable them to provide the necessary guidance, oversight and advice 
for  the  Board  to  operate  effectively.  All  Directors  are  encouraged  to  use  their  independent  judgement  and  to 
challenge all matters, whether strategic or operational.  

Jonathan Allis is currently the Company's only independent Non-Executive Director. The Company acknowledges 
that the guidance in the QCA Code is for a company to have at least two independent  Non-Executive Directors. 
However, the Directors are satisfied that the Company's board composition is appropriate given the Company's 
size and stage of development. All Directors are encouraged to use their independent judgement and to challenge 
all matters, whether strategic or operational. The Directors shall keep the position under regular review and to the 
extent additional independence is felt to be required on the Board, it shall be sought . 

The Board will seek to take into account any Board imbalances for future nominations. The Company is committed 
to a culture of equal opportunities for all employees regardless of gender. The Board aims to be diverse in terms 
of its range of culture, nationality and international experience. Give n the current phase of Polarean’s life cycle, 
the Board has determined that it is not practicable to set measurable objectives for achieving gender diversity. It 
is  the  Board’s  intention  as  the  size  and  complexity  of  the  Company  grows,  to  set  and  aim  to  ac hieve  gender 
diversity objectives pursuant to a defined diversity policy. 

Polarean Imaging plc 
21 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Corporate Governance Report  

Continued 

All of the Executive Directors work full time for the Company. The Chairman is expected to devote not less than 
52  days  per  annum and the Non-Executive  Directors are  each expected  to dedicate not less than  15 days  per 
annum to the Company’s affairs. The Chairman and other Non-Executive Directors endeavour to ensure that their 
knowledge of best practices and regulatory developments is continually up to date by attending relevant seminars 
and conferences.  

There  were  16  scheduled  board  meetings  held  during  2018.  The  table  below  sets  out  attendance  statistics  for 
each Director at Board and, where relevant, Committee meetings held during the financial year.  

Director 

Richard Morgan 
Richard Hullihen 
Kenneth West 
Bastiaan Driehuys 
Robert Bertoldi 
Jonathan Allis 
Juergen Laucht 

Board 
(16 meetings held) 
16/16 
16/16 
16/16 
13/16 
16/16 
9/16 
16/16 

Audit Committee 
(2 meetings held) 
2/2 
- 
- 
- 
2/2 

2/2 

Remuneration Committee 
(2 meetings held) 
2/2 
- 
- 
2/2 
- 
- 
2/2 

The  Board,  as  a  whole,  is  responsible  for  the  overall  management  of  the  Group  and  for  its  strategic  direction, 
including  approval  of  the  Group’s  strategy,  its  annual  business  plans  and  budgets,  the  interim  and  full  year 
financial  statements  and  reports,  any  dividend  proposals,  the  accounting  policies,  major  capital  projects,  any 
investments or disposals, its succession  plans and the monitoring of  financial performance against  budget and 
forecast and the formulation of the Group’s risk appetite including the  identification, assessment and monitoring 
of Polarean’s principal risks. In accordance with best practice, Polarean has adopted a formal schedule of Matters 
Reserved  for  the  Board.  These  are  reviewed  annually,  and  any  items  not  included  within  the   schedule  are 
delegated to the management team. 

In  order  to  keep  Director  skillsets  up  to  date,  the  Board  uses  third  parties  to  advise  the  Directors  of  their 
responsibilities including receiving advice from the Company’s external lawyers. The Board proposes to in troduce 
a facility for Directors to receive training on relevant developments on a more regular basis. The Board reviews 
the  appropriateness  and  opportunity  for  continuing  professional  development  in  order  to  keep  each  Director’s 
skillset up-to-date. In addition to their general Board responsibilities, Non-Executive Directors are encouraged to 
be  involved  in  specific  workshops  or  meetings,  in  line  with  their  individual  areas  of  expertise.  The  Board  shall 
review annually the appropriateness and opportunity for continuing professional development, whether formal or 
informal. 

Polarean’s Company Secretary, Stephen Austin, is responsible for ensuring that Board procedures are followed 
and that the Company complies with all applicable rules, regulations and oblig ations governing its operation, as 
well as helping the Chairman maintain excellent standards of corporate governance. There are processes in place 
enabling Directors to take independent advice at the Company’s expense in the furtherance of their duties, an d to 
have access to the advice and services of the Company Secretary. 

Board Committees 

The  Board  has  established  an  Audit  Committee  and  a  Remuneration  Committee  with  delegated  duties  and 
responsibilities. 

Audit Committee 

Robert  Bertoldi,  Non-Executive  Director,  is  Chairman  of  the  Audit  Committee.  The  other  members  of  the 
Committee  are  Richard  Morgan and Juergen Laucht.  The  Audit  Committee is  responsible  for ensuring that  the 
financial performance, position and prospects for the Group are p roperly monitored, controlled and reported on 
and for meeting the auditors and reviewing their reports relating to accounts and internal controls.  The Committee 
held 2 meetings during the year. A report by the Chairman of the Audit Committee is included on page  27. 

Remuneration Committee 

Richard Morgan, Non-Executive Director, is Chairman of the Remuneration Committee. The other members of the 
Committee are Bastiaan Driehuys and Juergen Laucht. The Remuneration Committee is responsible for reviewing 
performance  of  Executive  Directors  and  determining  the  remuneration  and  basis  of  service  agreement s.  The 
Remuneration Committee also determines the payment of any bonuses to Executive Director s and the grant of 
options. A report by the Chairman of the Remuneration Committee is included on page 25. 

Polarean Imaging plc 
22 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Corporate Governance Report  

Continued 

Nomination Committee 

The Company does not currently have a Nomination Committee, as the Board does not consider it appropriate to 
establish such a committee at this stage of the Company's development. Decisions which would usually be taken 
by the nomination committee will be taken by the Board as a whole. The Board as a whole  will also be responsible 
for AIM compliance. 

The Chairman and the Board continue to monitor and evolve the Company’s corporate governance structures and 
processes, and maintain that these will evolve over time, in line with the Company’s growth and development.    

Advisers 

The  Board  has  regular  contact  with  its  advisers  to  ensure  that  it  is  aware  of  changes  to  generally  accepted 
corporate  governance  procedures  and  requirements  and  that  the  Group  remains,  at  all  times,  compliant  with 
applicable  rules  and  regulations.  The  Company  holds  appropriate  insurance  cover  i n  respect  of  possible  legal 
action  against  its  Directors.  The  Company’s  Nomad  supports  the  Board’s  development,  specifically  providing 
guidance on corporate governance and other regulatory matters, as required.  

All  Directors  may  receive  independent  professional  advice  at  Polarean’s  expense,  if  necessary,  for  the 
performance of their duties.  

Board Performance Evaluation 

The structure of the Board is subject to continual review to ensure that it is appropriate for the Company. Over the 
next  12  months  the  Company  intends  to  review  the  performance  of  the  Board  as  a  whole  to  ensure  that  its 
members collectively function in an efficient manner, focusing more closely on defined objectives and targets for 
improving performance, as well as reviewing the effectiveness of each Committee.  

The  Directors  consider  that  the  Company  and  Board  are  not  yet  of  sufficient  size  for  a  full  Board  performance 
evaluation to make commercial and practical sense at the current time, although the  Board currently runs a self-
evaluation process whereby the Chairman annually assesses the individual cont ributions of each of the members 
of the team to ensure that:  

Their contribution is relevant and effective; 
That they are committed; and 

- 
- 
-  Where relevant, they have maintained their independence. 

Therefore,  the  Board  accepts  that  the  Company  does  not  comply  with  this  aspect  of  the  QCA  Code,  although 
frequent Board meetings/calls, the Directors discuss areas where they feel a change would be beneficial for the 
Company, and the Company Secretary remains on hand to provide advice. As the Company grows, it intends to 
expand the Board and, with expansion, re-consider the need for a formal Board evaluation. 

The Company has not yet adopted a policy on succession planning, in particular with regard to the  Company’s 
Chairman,  Richard  Morgan. The Company  will consider succession planning  in  respect  of the  Board and  other 
members  of  senior  management  as  appropriate,  as  part  of  its  review  of  Board  effectiveness  over  the  next  12 
months. 

Culture 

The  Board  recognises  that  its  decisions  regarding  strategy  and  risk  may  impact  the  corporate  culture  of  the 
Company as a whole and that this will impact the performance of the Company. It is aware that the tone set by 
the Board and by its decisions regarding strategy and risk may impact the corporate culture of the Company as a 
whole and on the way that employees and other stakeholders behave.  

The Company operates in a manner that encourages an open and respectful dialogue with employees, customers 
and other stakeholders and the Board considers that sound ethical values and behaviours are crucial to the ability 
of the Company to achieve its corporate objectives. The Group is committed to the highest standards of personal 
and professional ethical behavior, and this must be reflected in every aspect of the way in which the Company 
operates. The Board places great importance on this aspect of corporate life and seeks to ensure that this flows 
through  all  that  the  Company  does.  The  Directors  believe  that  the  Company  has  an  open  culture  facilitating 
comprehensive dialogue and feedback and enabling positive and constructive challenge.  

The  Directors  consider  that  at  present  the  Group  has  an  open  culture  facilitating  comprehensive  dialogue  and 
feedback  and  enabling positive  and constructive challenge.  The Executive  Directors  regularly meet  with senior 
management and discuss staff well-being, development and staff feedback. Employees are encouraged to engage 
directly with Directors, and the Group seeks to promote Group values and behavior through a top-down approach.  

Polarean Imaging plc 
23 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Corporate Governance Report  

Continued 

Anti-Bribery Policy  

The Group has in place appropriate guidance, training and implementation of procedures to ensure compliance 
with  the  UK  Bribery  Act.  The  Group  takes  a  zero-tolerance  approach  to  bribery  and  corruption  and  we  are 
committed to act professionally, fairly and with integrity in all our business dealings. Any breach of this policy will 
be regarded as a serious matter by the Company and is likely to result in disciplinary action and potentially the 
involvement of the police.  

Share Dealing 

The  Group  has  a  Share  Dealing  Code,  which  will  apply  to  any  person  discharging  management  responsibility, 
including  the  Directors and members of  the senior  management team  and any  closely  associated  persons  and 
applicable employees. 

The Share Dealing Code imposes restrictions beyond those that are imposed by law (including by FSMA and the 
Market  Abuse  Regulation  (EU)  No.596/2014  and  other  relevant  legislation)  and  its  purpose  is  to  ensure  that 
persons discharging managerial responsibility and persons connected with them do not abuse, and do not place 
themselves  under  suspicion  of  abusing,  price-sensitive  information  that  they  may  have  or  be  thought  to  have, 
especially in periods leading up to an announcement of both financial results and the results of the Group's clinical 
trials.  The  Share  Dealing  Code  sets  out  a  notification  procedure  which  is  required  to  be  followed  prior  to  any 
dealing in the Company's securities. 

Communication with Shareholders 

The Group is strongly committed to the maintenance of good investor relations and seeks, wherever possible to 
be a relationship of mutual understanding with both its institutional and private client inves tors. Additionally, the 
Board seeks to meet with shareholders whenever possible and to use the Group’s website www.polarean.com  to 
communicate with all shareholders.  The board also welcomes shareholders’ enquiries, which may  also be sent 
via the Group’s website. 

The corporate governance arrangements that the Board has adopted are designed to ensure that the Company 
delivers long-term value to its shareholders and that shareholders are able to express their views and expectations 
for the Company in a manner that encourages open dialogue with the Board. 

In addition to the publication of half-year and full year results statements, the Company provides frequent trading 
updates and makes its senior management team available to meet with shareholders, when there is opportunity 
for shareholders to voice their concerns, thoughts or needs. The Company has recently appointed an independent 
research company to publish reports on the Company, in order that more of its shareholders may obtain access 
to such information. 

Polarean Imaging plc 
24 

 
 
 
 
 
 
 
 
 
Remuneration Committee Report  

Dear Shareholder  

As the Chairman of Polarean’s Remuneration Committee, I present my first Remuneration Committee Report for 
the year ended 31 December 2018, which has been prepared by the Committee and approved by the Board.   

The Remuneration Committee is responsible for determining the remuneration  policy for the Executive Directors, 
and for overseeing the Company’s long-term incentive plans. The Board as a whole is responsible for determining 
Non-Executive Directors’ remuneration.  

The Committee will continue to monitor market trends and developments in order to assess those relevant for the 
Group’s future remuneration policy.  

Remuneration policy for 2018 and future years 

The  Remuneration  Committee  determines  the  Company’s  policy  on  the  structure  of  Executive  Directors’  and  if 
required, senior management’s remuneration. The objectives of this policy are to:   

•  Reward Executive Directors and senior management in a manner that ensures that they are properly incentivised 

and motivated to perform in the best interests of shareholders.  

•  Provide  a  level  of  remuneration  required  to  attract  and  motivate  high-calibre  Executive  Directors  and  senior 

management of appropriate calibre.  

•  Encourage value creation through consistent and transparent alignment of incentive arrangements with the agreed 

company strategy over the long term.  

•  Ensure the total remuneration packages awarded to Executive Directors, comprising both performance-related and 
non-performance-related remuneration, is designed to motivate the individual, align interests with shareholders and 
comply with corporate governance best practice. 

Objectives and Responsibilities 

The Remuneration Committee’s main responsibilities can be summarised as follows: 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

To determine the framework or broad policy for the remuneration of the Chairman, the Executive Directors, and 
such  other  senior  executives  as  it  is  requested  by  the  Board  to  consider.  The  remuneration  of  Non-Executive 
Directors shall be a matter for the Chairman and the Executive Directors of the Board. No Director shall be involved 
in any decisions as to their own remuneration; 

To determine such remuneration policy, taking into account all factors which it deems necessary (including relevant 
legal and regulatory requirements); 

To review the ongoing appropriateness and relevance of the remuneration policy, including policy comparisons 
with market competitors; 

To  design  and  determine  targets  for  any  performance  related  pay  schemes  operated  by  the  Company  and 
approving the total annual payments made under such schemes; 

To review the design of, and any changes to, all share incentive plans; 

To advise on any major changes in employee benefits structures throughout the Company;  

To review the structure, size and composition of the Board, including the skills, knowledge and experience; 

To give full consideration to succession planning; 

To recommend new Board appointments; and 

To consider any matter specifically referred to the Committee by the Board. 

Remuneration Policy for Non-Executive Directors 

Jonathan Allis, Juergen Laucht, Robert Bertoldi and I each receive a fee for our services as Directors, which is approved 
by the Board, mindful of the time commitment and responsibilities of our roles and of current market rates for comparable 
organisations and appointments. 

Polarean Imaging plc 
25 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Remuneration Committee Report  

Continued 

Remuneration decisions for 2018 

Bonuses payable for the year ended 31 December 2018 was US$nil (2017: US$nil).   

Remuneration Committee Effectiveness 

The Committee is due to perform a self-assessment of its effectiveness during the second half of 2019. 

Further information on Directors’ remuneration, including Directors’ emoluments, share options and warrants holdings 
can be found in the Directors’ Report on pages 16-18.  

Richard Morgan 
Chairman of the Remuneration Committee 
26 June 2019 

Polarean Imaging plc 
26 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Audit Committee Report  

Dear Shareholder  

As  the  Chairman  of  Polarean’s  Audit  Committee,  I  present  my  first  Audit  Committee  Report  for  the  year  ended  31 
December 2018, which has been prepared by the Committee and approved by the Board.  

The Committee is responsible for reviewing and reporting to the Board on financial reporting, internal control and risk 
management, and for reviewing the performance, independence and effectiveness of the external auditors in carrying 
out the statutory audit.  

During  the  year,  the  Committee’s  primary  activity  involved  meeting  with  the  external  auditors,  considering  material 
issues and areas of judgement, and reviewing and approving the interim and year end results and accounts.  

In addition, the Committee reviewed the audit provided by Crowe UK LLP, the Group’s external auditors. The Committee 
concluded that Crowe UK LLP are delivering the necessary audit scrutiny. 

Accordingly, the Committee recommended to the Board that Crowe UK LLP be re-appointed for the next financial year.  

During 2018, the Committee:  

•  met with the external auditors to review and approve the annual audit plan and receive their findings and report 

on the annual audit;  
considered  significant  issues  and  areas  of  judgement  with  the  potential  to  have  a  material  impact  on  the 
financial statements;  
considered the integrity of the published financial information and whether the Annual Report and Accounts 
taken as a whole are fair, balanced and understandable and provide the information necessary to assess the 
Group’s position and performance, business model and strategy; and  
reviewed and approved the interim and year end results and accounts.   

• 

• 

• 

In the coming year, in addition to the Committee’s ongoing duties, the Committee will:  

• 

• 

consider significant issues and areas of judgement with the potential to have a material impact on the financial 
statements; and 
keep  the  need  for  an  internal  audit  function  under  review,  having  regard  to  the  Company’s  strategy  and 
resources.  

Audit Committee Effectiveness 

The Committee is due to perform an assessment of its effectiveness during the second half of 2019.  

Robert Bertoldi 
Chairman of the Audit Committee 
26 June 2019 

Polarean Imaging plc 
27 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Independent Auditors’ report to the members of 

 Polarean Imaging plc 

Opinion   

We have audited the  financial statements of Polarean Imaging plc (the “Parent Company”) and its subsidiaries (the 
“Group”) for the year ended 31 December 2018, which comprise: 

• 
• 
• 
• 
• 

the Group statement of comprehensive income for the year ended 31 December 2018; 
the Group and parent company statements of financial position as at 31 December 2018; 
the Group and parent company statements of cash flows for the year then ended; 
the Group and parent company statements of changes in equity for the year then ended; and 
the notes to the financial statements, including a summary of significant accounting policies. 

The financial reporting framework that has been applied in the preparation of the financial statements is applicable law 
and International Financial Reporting Standards (IFRSs) as adopted by the European Union. 

In our opinion: 

• 

• 

• 

• 

the financial statements give a true and fair view of the state of the Group’s and of the Parent Company's affairs 
as at 31 December 2018 and of the Group’s loss for the period then ended; 
the group financial statements have been properly prepared in accordance with IFRSs as adopted by the European 
Union;  
the parent company financial statements have been properly prepared in accordance with IFRSs as adopted by 
the European Union as applied in accordance with the provisions of the Companies Act 2006; and 
the financial statements have been prepared in accordance with the requirements of the Companies Act 2006.  

Basis for opinion  

We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. 
Our  responsibilities  under  those  standards  are  further  described  in  the  Auditor’s  responsibilities  for  the  audit  of  the 
financial statements section of our report. We are independent of the Group in accordance with the ethical requirements 
that are relevant to our audit of the financial statements in the UK, including the FRC’s Ethical Standard, and we have 
fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we 
have obtained is sufficient and appropriate to provide a basis for our opinion. 

Conclusions relating to going concern 

We have nothing to report in respect of the following matters in relation to which ISAs (UK) require us to report to you 
when: 

• 

• 

The directors’ use of the going concern basis of accounting in the preparation of the financial statements is not 
appropriate; or 
The  directors  have  not  disclosed  in  the  financial  statements  any  identified  material  uncertainties  that  may  cast 
significant doubt about the Group’s or the parent company’s ability to continue to adopt the going concern basis of 
accounting for a period of at least twelve months from the date when the financial statements are authorised for 
issue.  

Overview of our audit approach 

Materiality 

In planning and performing our audit we applied the concept of materiality. An item is considered material if it could 
reasonably be expected to change the economic decisions of a user of the financial statements. We used the concept 
of materiality to both focus our testing and to evaluate the impact of misstatements identified. Based on our professional 
judgement, we determined overall materiality for the Group financial statements as a whole to be US$250,000, which 
represents  approximately  5%  of  the  Group’s  operating  loss.  We  use  a  different  level  of  materiality  (‘performance 
materiality’) to determine the extent of our testing for the audit of the financial statements.  Performance materiality is 
set based on the audit materiality as adjusted for the judgements made as to the entity risk and our evaluation of the 
specific risk of each audit area having regard to the internal control environment.   

Where  considered  appropriate  performance  materiality  may  be  reduced  to  a  lower  level,  such  as,  for  related  party 
transactions and directors’ remuneration. 

Polarean Imaging plc 
28 

 
 
 
 
 
 
 
 
 Independent Auditors’ report to the members of 

 Polarean Imaging plc 

continued 

We agreed with the Audit Committee to report to it all identified errors in excess of US$6,000. Errors below that threshold 
would also be reported to it if, in our opinion as auditor, disclosure was required on qualitative grounds. 

Overview of the scope of our audit 

Polarean Imaging plc and its subsidiaries are accounted for from one operating location in North Carolina, USA. Our 
audit was conducted from this location and all Subsidiary companies were within the scope of our audit testing. 

Key Audit Matters 

Key audit matters are those matters that, in our professional judgement, were of most significance in our audit of the 
financial  statements  of  the  current  period  and  include  the  most  significant  assessed  risks  of  material  misstatement 
(whether or not due to fraud) that we identified. These matters included those which had the greatest effect on: the 
overall audit strategy, the allocation of resources in the audit; and directing the efforts of the engagement team. These 
matters were addressed in the context of our audit of the financial statements as a whole, and in forming our opinion 
thereon, and we do not provide a separate opinion on these matters. 

This is not a complete list of all risks identified by our audit. 

How the scope of our audit addressed the key audit 
matter 

We designed procedures to test each revenue 
stream and considered whether the revenue recognition 
policy applied to the revenue stream was appropriate. 
Our testing in this area included agreeing that revenue was 
appropriately recognised. This included cut off procedures.  

Key audit matter 

Revenue recognition 

Revenue  is  a  significant  figure  in  these  financial 
statements and is generated from various streams. 

Our audit risk focuses on the risk that revenues may be 
to  meet  market  expectations.  We 
overstated 
specifically 
revenue 
risks 
identified 
transactions recorded in the year may not exist (the risk 
of  fictitious  revenue  transactions)  or  that  revenues 
transactions recorded in the year may not have been 
despatched  to  the  customer  before  year  end  and 
therefore  may  have  been  recorded  in  the  incorrect 
period. 

that  either 

The accounting policy is documented in note 3 

Our audit procedures in relation to the above matter was designed in the context of our audit opinion as a whole. They 
were not designed to enable us to express an opinion on these matters individually and we express no such opinion. 

Other information 

The directors are responsible for the other information. The other information comprises the information included in the 
annual  report,  other  than  the  financial  statements  and  our  auditor’s  report  thereon.  Our  opinion  on  the  financial 
statements does not cover the other information and, except to the extent otherwise explicitly stated in our report, we 
do not express any form of assurance conclusion thereon. 

In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing 
so, consider  whether  the  other  information is materially  inconsistent  with  the  financial statements  or  our  knowledge 
obtained in the audit or otherwise appears to be materially misstated. If we identify such material inconsistencies or 
apparent material misstatements, we are required to determine whether there is a material misstatement in the financial 
statements or a material misstatement of the other information. If, based on the work we have performed, we conclude 
that there is a material misstatement of this other information, we are required to report that fact. 

We have nothing to report in this regard. 

Opinion on other matter prescribed by the Companies Act 2006 

In our opinion based on the work undertaken in the course of our audit  

• 

• 

the information given in the strategic report and the directors' report for the financial year for which the financial 
statements are prepared is consistent with the financial statements; and 

the directors’ report and strategic report have been prepared in accordance with applicable legal requirements. 

Polarean Imaging plc 
29 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Independent Auditors’ report to the members of 

 Polarean Imaging plc 

continued 

Matters on which we are required to report by exception 

In light of the knowledge and understanding of the group and the parent company and their environment obtained in 
the course of the audit, we have not identified material misstatements in the strategic report or the directors’ report. 

We have nothing to report in respect of the following matters where the Companies Act 2006 requires  us to report to 
you if, in our opinion: 

• 

• 

• 

adequate accounting records have not been kept by the parent company, or returns adequate for our audit 
have not been received from branches not visited by us; or 

the parent company financial statements are not in agreement with the accounting records and returns; or 

certain disclosures of directors' remuneration specified by law are not made; or 

•  we have not received all the information and explanations we require for our audit. 

Responsibilities of the directors for the financial statements 

As explained more fully in the directors’ responsibilities statement set out on page 19, the directors are responsible for 
the preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal 
control  as  the  directors  determine  is  necessary  to  enable  the  preparation  of  financial  statements  that  are  free  from 
material misstatement, whether due to fraud or error. 

In preparing the financial statements, the directors are responsible for assessing the group’s and parent company’s 
ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going 
concern basis of accounting unless the directors either intend to liquidate the group or the parent company or to cease 
operations, or have no realistic alternative but to do so. 

Auditor’s responsibilities for the audit of the financial statements 

Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from 
material  misstatement,  whether  due  to  fraud  or  error,  and  to  issue  an  auditor’s  report  that  includes  our  opinion. 
Reasonable assurance is a high level of assurance but is not a guarantee that an audit conducted in accordance with 
ISAs (UK) will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and 
are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic 
decisions of users taken on the basis of these financial statements. 

A further description of our responsibilities for the audit of the financial statements is located on the Financial Reporting 
Council’s website at: www.frc.org.uk/auditorsresponsibilities. This description forms part of our auditor’s report.  

Use of our report 

This report is made solely to the Group's members, as a body, in accordance with Chapter 3 of Part 16 of the Companies 
Act 2006. Our audit work has been undertaken so that we might state to the Group's members those matters we are 
required to state to them in an auditor's report and for no other purpose. To the fullest extent permitted by law, we do 
not accept or assume responsibility to anyone other than the Group and the Group's members as a body, for our audit 
work, for this report, or for the opinions we have formed. 

Stephen Bullock (Senior Statutory Auditor) 
for and on behalf of  
Crowe U.K. LLP 
Statutory Auditor 
London 

26 June 2019 

Polarean Imaging plc 
30 

 
 
 
 
 
 
 
 
 
 
 
 
 
 Consolidated Statement of Comprehensive Income 

for the year ended 31 December 2018 

Revenue 
Cost of sales 
Gross profit 

Administrative expenses 
Depreciation 
Amortisation 
Selling and distribution expenses 
Share-based payment expense 
Total administrative expenses 
Operating loss 
Finance income 
Finance expense 
Loss before tax 
Taxation 
Loss for the year and total other comprehensive expense 

Loss per share 

Basic and diluted (US$) 

Notes 
4 

11 
12 

19 

6 
7 
7 

10 

2018 
US$ 
2,439,139 
(633,463) 
1,805,676 

(6,161,916) 
(10,140) 
(616,852) 
(31,766) 
(251,790) 
(7,072,464) 
(5,266,788) 
184 
(188,055) 
(5,454,659) 
- 
(5,454,659) 

2017 
US$ 
1,237,163 
(297,215) 
939,948 

(4,051,000) 
(7,478) 
(361,746) 
(28,752) 
(414,866) 
(4,863,842) 
(3,923,894) 
129 
(34,056) 
(3,957,821) 
- 
(3,957,821) 

    9 

(0.078) 

(0.139) 

The results reflected above relate to continuing activities.  

There  is  no  recognised  income  or  expense  for  the  year  other  than  the  loss  above  and  therefore  no  separate 
statement of other comprehensive income has been presented. 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements. 

Polarean Imaging plc 
31 

 
 
 
 
 
 
 
 
 
 
  
 
 
 
  
  
 
  
  
  
 
 
 
 
 
 
 
 
  
  
 
 
 
  
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Consolidated Statement of Financial Position 

as at 31 December 2018 

Notes 

ASSETS 
Non-current assets 
Property, plant and equipment 
Intangible assets 
Trade and other receivables 

Current assets 
Inventories 
Trade and other receivables 
Cash and cash equivalents 

TOTAL ASSETS 

EQUITY AND LIABILITIES 
Equity attributable to holders of the parent 
Share capital 
Share premium 
Group re-organisation reserve 
Other equity 
Share-based payment reserve 
Accumulated losses 

Non-current liabilities 
Provision for contingent consideration 
Deferred income 

Current liabilities 
Trade and other payables 
Borrowings 
Deferred income 

TOTAL EQUITY AND LIABILITIES 

11 
12 
14 

15 
14 
16 

17 
18 
18 
18 
19 
18 

20 
21 

22 
23 
21 

2018 
US$ 

2017 
US$ 

17,752 
4,044,398 
12,539 

4,074,689 

651,781 
4,226,585 
875,601 

5,753,967 

9,828,656 

21,341 
4,661,250 
12,539 

4,695,130 

649,860 
488,861 
960,217 

2,098,938 

6,794,068 

49,427 
11,063,075 
7,813,337 
- 
1,078,335 
(12,212,767) 

23,291 
1,448,037 
7,813,337 
87,305 
826,545 
(6,758,108) 

7,791,407 

3,440,407 

316,000 
70,726 

386,726 

316,000 
- 

316,000 

1,590,482 
5,213 
54,828 

1,650,523 

9,828,656 

1,906,376 
1,104,723 
26,562 

3,037,661 

6,794,068 

These Financial Statements were approved and authorised for issue by the Board of Directors on  26 June 2019 
and were signed on its behalf by: 

Richard Morgan  
Non-Executive Chairman 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements.

Polarean Imaging plc 
32 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 Company Statement of Financial Position 

as at 31 December 2018 

Notes 

ASSETS 
Non-current assets 
Investment in subsidiary 

Current assets 
Trade and other receivables 
Cash and cash equivalents 

TOTAL ASSETS 

EQUITY AND LIABILITIES 
Equity attributable to holders of the parent 
Share capital 
Share premium 
Merger reserve 
Other equity 
Share-based payment reserve 
Accumulated losses 

Current liabilities 
Trade and other payables 
Borrowings 

TOTAL EQUITY AND LIABILITIES 

13 

14 
16 

17 
18 
18 
18 
19 
18 

22 
23 

2018 
US$ 

2017 
US$ 

4,342,848 

4,342,848 

4,342,848 

4,342,848 

9,370,611 
235,766 

9,606,377 

13,949,225 

1,891,495 
23,106 

1,914,601 

6,257,449 

49,427 
11,063,075 
4,322,527 
- 
773,304 
(2,287,282) 

13,921,051 

23,291 
1,448,037 
4,322,527 
87,305 
521,514 
(956,714) 

5,445,960 

28,174 
- 

28,174 

25,742 
785,747 

811,489 

13,949,225 

6,257,449 

The loss for the financial year dealt with in the financial statements of the parent Company was  US$1,330,568 
(2017: US$956,714). 

These Financial Statements were approved and authorised for issue by the Board of Directors on  26 June 2019 
and were signed on its behalf by: 

Richard Morgan  
Non-Executive Chairman 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements.

Polarean Imaging plc 
33 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Consolidated Statement of Changes in Equity 

for the year ended 31 December 2018 

Share capital  
US$ 

Share premium 
US$ 

Other equity 
US$ 

As at 1 January 2017 
Comprehensive income 
Loss for the year 
Transactions with owners 
Issue of shares  
Share issue costs 
Share-based payment expense 
Group re-organisation 
Convertible loans 

As at 31 December 2017 
Comprehensive income 
Loss for the year 
Transactions with owners 
Issue of shares  
Share issue costs 
Share-based payment expense 

As at 31 December 2018 

1 

- 

2,970 
- 
- 
20,320 
- 

23,291 

- 

26,136 
- 
- 

49,427 

- 

- 

1,982,094 
(534,057) 
- 
- 
- 

1,448,037 

- 

- 

- 
- 
- 
- 
87,305 

87,305 

Share-based 
payment reserve 
US$ 

Group re-org 
reserve 
US$ 

Accumulated losses 
US$ 

Total equity 
US$ 

238,172 

1,976,367 

(2,800,287) 

(585,747) 

- 

- 

(3,957,821) 

(3,957,821) 

- 
173,507 
414,866 
- 
- 

- 
- 
- 
5,836,970 
- 

- 
- 
- 
- 
- 

826,545 

7,813,337 

(6,758,108) 

1,985,064 
(360,550) 
414,866 
5,857,290 
87,305 

3,440,407 

- 

- 

- 

10,161,474 
(546,436) 
- 

11,063,075 

(87,305) 
- 
- 

- 
- 
251,790 

- 

- 
- 
- 

(5,454,659) 

(5,454,659) 

- 
- 
- 

10,100,305 
(546,436) 
251,790 

- 

1,078,335 

7,813,337 

(12,212,767) 

7,791,407 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements.

Polarean Imaging plc 
34 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Company Statement of Changes in Equity 

for the year ended 31 December 2018 

Share capital  
US$ 

Share premium 
US$ 

Other equity 
US$ 

Share-based 
payment reserve 
US$ 

Merger reserve 
US$ 

Accumulated 
losses 
US$ 

Total equity 
US$ 

- 

- 

4,322,527 
- 
- 
- 

4,322,527 

- 

- 
- 
- 

- 

1 

(956,714) 

(956,714) 

- 
- 
- 
- 

(956,714) 

6,327,911 
(360,550) 
348,007 
87,305 

5,445,960 

(1,330,568) 

(1,330,568) 

- 
- 
- 

10,100,305 
(546,436) 
251,790 

13,921,051 

4,322,527 

(2,287,282) 

As at 1 January 2017 
Comprehensive income 
Loss for the year 
Transactions with owners 
Issue of shares  
Share issue costs 
Share-based payment expense 
Convertible loans 

As at 31 December 2017 
Comprehensive income 
Loss for the year 
Transactions with owners 
Issue of shares  
Share issue costs 
Share-based payment expense 

As at 31 December 2018 

1 

- 

23,290 
- 
- 
- 

23,291 

- 

26,136 
- 
- 

49,427 

- 

- 

1,982,094 
(534,057) 
- 
- 

1,448,037 

- 

- 

- 
- 
- 
87,305 

87,305 

- 

- 

10,161,474 
(546,436) 
- 

11,063,075 

(87,305) 
- 
- 

- 

- 

- 

- 
173,507 
348,007 
- 

521,514 

- 

- 
- 
251,790 

773,304 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements. 

Polarean Imaging plc 
35 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consolidated Statement of Cash Flows 

for the year ended 31 December 2018 

Cash flows from operating activities  
Loss before tax 
Adjustments for non-cash/non-operating items: 
Depreciation of plant and equipment 
Amortisation of intangible assets 
Share-based payment expense 
Interest paid 
Interest received 

2018                   
US$ 

2017 
US$              

(5,454,659) 

(3,957,821) 

10,140 
616,852 
251,790 
188,055 
(184) 

7,478 
361,746 
414,866 
34,056 
(129) 

Operating cash flows before movements in working capital 

(4,388,006) 

(3,139,804) 

Increase in inventories 

Increase in trade and other receivables 
(Decrease)/increase in trade and other payables 
Increase/(decrease) in deferred income 

Net cash used in operations 

Cash flows from investing activities 
Purchase of plant and equipment 
Interest received 

Net cash used in investing activities 

Cash flows from financing activities 
Issue of shares 
Interest paid 
Issue of notes and loans 
Repayment of notes and loans  

Net cash generated by financing activities 

Net (decrease)/increase in cash and cash equivalents 

Cash and cash equivalents at the beginning of year 

Cash and cash equivalents at end of year 

(1,921) 

(69,517) 
(315,894) 
98,992 

(328,199) 

(440,931) 
1,343,861 
(50,618) 

(4,676,346) 

(2,615,691) 

(6,551) 
184 

(6,367) 

5,093,775 
(188,055) 
5,213 
(312,836) 

4,598,097 

(84,616) 

960,217 

875,601 

(16,834) 
129 

(16,705) 

2,481,808 
(34,056) 
1,047,014 
- 

3,494,766 

862,370 

97,847 

960,217 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements

Polarean Imaging plc 
36 

 
 
 
 
  
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Company Statement of Cash Flows 

for the year ended 31 December 2018 

Cash flows from operating activities  
Loss before tax 

Adjustments for non-cash/non-operating items: 

Share-based payment expense 

Year ended  
31 December 
2018 
US$ 

Year ended  
31 December 
2017 
US$ 

(1,330,568) 

(956,714) 

251,790 

348,007  

Operating cash flows before movements in working capital 

(1,078,778) 

(608,707) 

Increase in trade and other payables 

Net cash used by operations 

Cash flows from financing activities 

Issue of shares 

Loans to intercompany 

Issue of notes and loans 

Net cash generated by financing activities 

Increase in cash and cash equivalents 

Cash and cash equivalents at the beginning of period 

Cash and cash equivalents at end of period 

2,433 

25,742 

(1,076,345) 

(582,965) 

5,099,914 

1,624,514 

(3,810,909) 

(1,851,022) 

- 

1,289,005 

212,660 

23,106 

235,766 

832,579 

606,071 

23,106 

- 

23,106 

The accompanying notes on pages 38 to 57 are an integral part of these financial statements.

Polarean Imaging plc 
37 

 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 

1 

General information 

The  Company  is  incorporated  in  England  and  Wales  under  the  Companies  Act  2006.  The  registered  number  is 
10442853 and its registered office is at 27-28 Eastcastle Street, London, W1W 8DH. The Company is listed on AIM 
of the London Stock Exchange. 

The Company is the parent company of Polarean, Inc (the “Subsidiary”, together the “Group”). The principal activity of 
the  Group  is  developing  next  generation  medical  imaging  technology.  The  Subsidiary  is  incorporated  in  the  United 
States of America and has a registered office of 2500 Meridian Parkway #175, Durham, NC 27713, USA. 

2 

Adoption of new and revised International Financial Reporting Standards 

Standards and interpretations adopted during the year 

Information  on  new  standards,  amendments  and  interpretations  that  are  relevant  to  the  Group’s  annual  report  and 
accounts is provided below.  

IFRS 9 ‘Financial Instruments’ 
IFRS 9 uses a single approach to determine whether a financial asset is  measured at amortised cost or fair value, 
replacing the many different rules in IAS 39. The approach in IFRS 9 is based on how an entity manages its financial 
instruments (its business model) and the contractual cash flow characteristics of the financial assets. The Group has 
considered  the  implications  of  IFRS  9  to  have  an  immaterial  impact,  as  detailed  in  the  financial  assets  accounting 
policy. 

IFRS 15 ‘Revenue from Contracts with Customers’ 
IFRS  15  is  intended  to  clarify  the  principles  of  revenue  recognition  and  establish  a  single  framework  for  revenue 
recognition. This supersedes IAS 18 Revenue and the core principle is that an entity should recognise revenue to depict 
the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity 
expects to be entitled in exchange for those goods or services. The Group has considered the implications of IFRS 15 
to have an immaterial impact, as detailed in the revenue recognition accounting policy.  

Certain other new standards and interpretations have been issued but are not expected to have a material impact on 
the Group's annual report and accounts. 

New and revised IFRS Standards in issue but not yet effective 

At the date of authorisation of these financial statements, The Group has not applied the following new and revised 
IFRS Standards that have been issued but are not yet effective.  

IFRS 16 ‘Leases’, effective 1 January 2019 
The IASB has published IFRS 16 ‘Leases’, completing its long-running project on lease accounting. The new Standard, 
which is effective for accounting periods beginning on or after 1 January 2019, requires lessees to account for leases 
‘on-balance sheet’ by recognising a ‘right-of-use’ asset and a lease liability. The date of initial application of IFRS 16 
for the Group will be 1 January 2019. It will affect most companies that report under IFRS and are involved in leasing 
and will have a substantial impact on the annual report and accounts of lessees of property and high value equipment. 
This standard has been endorsed by the European Union.  

The Group’s management has carried out an impact review of the implementation of IFRS 16 and has decided it will 
apply  the  modified  retrospective  adoption  method  in  IFRS  16,  and,  therefore,  will  only  recognise  leases  on  the 
Statement of Financial Position  as at 1 January 2019. In addition, it has decided to measure right-of-use assets by 
reference to the measurement of the lease liability on that date. This will ensure there is no immediate impact to net 
assets on that date.  

At 31 December 2018 operating lease commitments amounted to  US$183,421 (see note 24), which is expected to 
reduce to US$109,899 at 31 December 2019. Assuming the Group’s lease commitments remain at this level, the effect 
of discounting those commitments is anticipated to result in right-of-use assets and lease liabilities of approximately 
US$115,000 being recognised on 1 January 2019. However, further work still needs to be carried out to determine 
whether and when extension and termination options are likely to be exercised, which will result in the actual liability 
recognised being higher than this. 

Instead of recognising an operating expense for its operating lease payments, the group will instead recognise interest 
on its lease liabilities and amortisation on its right-of-use assets. This will increase reported EBITDA by the amount of 
its current operating lease cost, which for the year ended 31 December 2018 was approximately US$73,000. 

There are no other standards issued which are expected to have a material impact on the financial statements.

Polarean Imaging plc 
38 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
Continued 

3 

Significant accounting policies 

Basis of preparation 

These  financial  statements  have  been  prepared  in  accordance  with  International  Financial  Reporting  Standards  as 
adopted by the European Union (“IFRS”) and under the historical cost convention, as modified by the use of fair value 
for financial instruments measured at fair value. The financial statements are presented in United States Dollars (“US$”) 
except where otherwise indicated. 

The principal accounting policies adopted in the preparation of the financial statements are set out below. The policies 
have been consistently applied to all the years presented, unless otherwise stated. 

Going concern 

The Directors consider the going concern basis of preparation to be appropriate in preparing the financial statements.  

The Group is in its development stage and has not yet moved to full commercial exploitation of its IP. During the year 
ended 31 December 2018 the Group recorded a loss after tax of US$5,454,659 (2017: loss of US$3,957,821) and a 
net cash outflow from operating activities of US$4,676,346 (2017: US$2,615,691).   

On 28 December 2018 the Group raised proceeds of US$4.0 million (excluding expenses) from investors by the issue 
of shares of which US$3.7 million remain outstanding at year-end. 

In considering the appropriateness of this basis of preparation, the Directors have reviewed the Group’s working capital 
forecasts  for  a  minimum  of  12  months  from  the  date  of  the  approval  of  this  financial  information.    Based  on  their 
consideration the Directors have reasonable expectation that the Group has adequate resources to continue for the 
foreseeable future and that carrying values of intangible assets are supported.  Thus, they continue to adopt the going 
concern basis of accounting in preparing this financial information. 

Share capital  

Ordinary shares are classified as equity. Incremental costs directly attributable to the issue of new shares are shown 
in share premium as a deduction from the proceeds. 

Government and other grants  

Grants are not recognised until there is a reasonable assurance that the Group will comply with the conditions attaching 
to  them  and  that  the  grants  will  be  received.  Grants  are  treated  as  deferred  income  and  released  to  the  income 
statement on the achievement of the relevant performance criteria. 

Inventory 

Inventories are measured at the lower of cost and net realisable value. The cost of inventories is based on the weighted 
average cost principle and includes expenditure incurred in inventories, adjusted for rebates, and other costs incurred 
in bringing them to their existing location. 

Cash and cash equivalents  

Cash and cash equivalents comprise cash balances and call deposits with an original maturity of three months or less.  

Polarean Imaging plc 
39 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

3 

Significant accounting policies continued 

Basis of consolidation 

The consolidated financial statements are for the year ended 31 December 2018. They have been prepared in 
accordance  with  the  requirements  of  International  Financial  Reporting  Standards  (IFRS)  as  adopted  by  the 
European Union (EU) and with those parts of the Companies Act 2006 applicable to companies reporting under 
IFRS. 

The measurement bases and principal accounting policies of the Group are set out below.  On 30 May 2017 Polarean 
Merger-Sub, Inc., a Subsidiary of the Subsidiary, completed a merger process under which it acquired substantially all of 
the assets of m2m Imaging Corp (“m2m”), a portfolio company of Amphion Innovations plc engaged in the development of 
high-performance MRI RF coils for the global research market, primarily in micro-imaging. By 2016 m2m had been inactive 
for several years due to an inability to raise funds. At the date of the merger the assets of m2m were its technology and 
patents. The merger was effected by way of court sanction in the process of which the Subsidiary acquired, through a 
special purpose entity, Polarean Merger Sub, Inc. the assets of another special purpose entity, m2m Merger Sub, Inc., with 
m2m Merger Sub, Inc. being the surviving entity. After the reporting date, on 1 September 2017, m2m Merger Sub, Inc. 
was merged into the Subsidiary with the Subsidiary being the surviving entity, the effect being that m2m Merger Sub, Inc. 
was collapsed, and the Subsidiary had acquired the m2m assets. 

As part of the arrangements for the merger 576,430 shares in the Subsidiary were issued to the former shareholders in 
m2m with the intention that all parties would exchange their stock in Polarean, Inc. for shares in the Group on a pro rata 
basis as soon as practicable.  

The Directors consider the merger between the Subsidiary and m2m Acquisition, Inc. as a consequence of which the group 
acquired the exclusive worldwide rights to m2m’s technology and patents does not meet the definition of an acquisition of 
a business as set out in IFRS3 and has therefore been accounted for as the acquisition of an asset or a group of assets 
that does not constitute a business.  

IFRS  3  requires  that  in  such cases  the  acquirer shall  identify  and  recognise  the  individual  identifiable  assets  acquired 
(including those assets that meet the definition of, and recognition criteria for, intangible assets in IAS 38 Intangible assets) 
and to allocate the cost of the individual identifiable assets and liabilities on the basis of their relative fair values at the date 
of purchase. Such a transaction or event does not give rise to goodwill.  

The provisional estimate of the fair value of the assets acquired under the merger arrangement of US$4,999,996 represents 
the aggregate estimated value of the financial obligations of the former m2m shareholders which were converted into equity 
in m2m prior to the merger agreement 

The Directors consider the acquisition of the entire issued common stock of the Subsidiary by the Company in exchange 
for equivalent equity participation in the Company to be a group re-organisation and not a business combination and to fall 
outside the scope of IFRS 3. Having considered the requirements of IAS 8 and the relevant UK and US guidance, the 
transaction has been accounted for on a merger or pooling of interest basis as if both entities had always been combined, 
using book values, with no fair value adjustments made nor goodwill recognised. 

Polarean Imaging plc 
40 

 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

3 

Significant accounting policies continued 

Revenue recognition 

Revenue comprises the fair value of the sale of goods and rendering of services to external customers, net of applicable 
sales tax, rebates, promotions and returns.  

Contracts and obligation 

The majority of customer contracts have three main elements that the Group provides to the customer: 

- 
- 
- 

Sale of polarisers; 
Sale of parts and upgrades; and 
Provision of service.  

The sale of polarisers is seen as a distinct performance obligation and revenue is recognised at a point in time. The 
customer can benefit from the use of the polarisers when supplied and is not reliant on the Group to provide the parts 
and upgrades or service, and therefore revenue from the sale of polarisers is recognised in full when supplied to the 
customer.  

The second performance obligation is the sale of parts and upgrades. The customer can benefit from the use of the 
parts and upgrade when supplied and is not reliant on the Group to provide the service, and therefore revenue from 
the sale of parts and upgrades is recognised in full when supplied to the customer. 

The third performance obligation is the provision of preventive maintenance service. Revenue from the provision of 
preventive  maintenance  service  is  recognised  in  the  period  in  which  the  services  are  provided  over  the  life  of  the 
contract.   

Determining the transaction price 

The transaction price is determined as the fair value of the Group expects to receive over the course of the contract.  
There are no incentives given to customers that would have a material effect on the financial statements. 

Allocate the transaction price to the performance obligations in the contract 

The allocation of the transaction price to the performance obligations in the contract is non-complex for the Group. 
There is a fixed unit price for each product or service sold. Therefore, there is limited judgement involved in allocating 
the contract price to each unit ordered.  

Recognise revenue when or as the entity satisfies its performance obligations 

The overarching terms are consistent in each contract.  

The sale of polarisers is seen as a distinct performance obligation and revenue is recognised at a point in time, when 
supplied to the customer, as the customer can benefit from the use of the polarisers when supplied.  

The sale of parts and upgrades is seen as a distinct performance obligation and revenue is recognised at a point in 
time, when supplied to the customer, as the customer can benefit from the use of the parts and upgrade when supplied.  
The provision of service is seen a as distinct performance obligation and revenue is recognised as the Group provides 
these services for the duration of the contract, i.e. over time. Any unexpired portion of a service contract or payment 
received in advance in respect of service contracts either partially completed or not started, are included in deferred 
income and released over their remaining term. 

Polarean Imaging plc 
41 

 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

3 

Significant accounting policies continued 

Property, plant and equipment  

Owned assets  
Items of property, plant and equipment are stated at cost or deemed cost less accumulated depreciation and impairment 
losses.  Cost  includes  the  original purchase  price  of  the  asset  and  the  costs  attributable  to  bringing  the  asset to  its 
working condition for its intended use. When parts of an item of property, plant and equipment have different useful 
lives, those components are accounted for as separate items of property, plant and equipment.  

Subsequent costs are included in the asset’s carrying amount or recognised as a separate asset, as appropriate, only 
when it is probable that future economic benefits associated with the item will flow to the Group and the cost of the item 
can be measured reliably. 

Depreciation  
Depreciation is charged to profit or loss on a straight-line basis over the estimated useful lives of each part of an item 
of property, plant and equipment. The estimated useful lives are as follows:  

●  Computer and IT equipment – 33% straight line 
●  Leasehold improvements – 20% straight line 
●  Laboratory equipment – 20% straight line 

The residual values, useful lives and depreciation methods are reviewed, and adjusted if appropriate, or if there is an 
indication of a significant change since the last reporting date.  

Gains and losses on disposals are determined by comparing the proceeds with the carrying amount and are recognised 
within “other operating income” in the statement of comprehensive income.  

Intangible Assets 

Patents and related rights which are acquired through a business combination, are assessed by reviewing their net 
present value of future cash flows. Patents are currently amortised over their useful life, not exceeding 10 years.  

Internally generated intangible assets – research costs are costs incurred in research activities and are recognised as 
an  expense  in  the  period  in  which  they  are  incurred.  An  internally  generated  intangible  asset  arising  from  the 
development of commercial technologies is recognised only if all of the following conditions are met: 

• 
• 
• 
• 
• 
• 

it is probable that the asset will create future economic benefits; 
the development costs can be measured reliably; 
technical feasibility of completing the intangible asset can be demonstrated; 
there is the intention to complete the asset and use or sell it; 
there is the ability to use or sell the asset; and 
adequate technical, financial and other resources to complete the development and to use or sell the asset 
are available. 

At this time the Directors consider that the Group does not meet all of those conditions and development costs are 
therefore recorded as expense in the period in which the cost is incurred.  

Impairment of non-financial assets 

Non-financial  assets  are  reviewed  for  impairment  whenever  events  or  changes  in  circumstances  indicate  that  the 
carrying amount may not be recoverable. An impairment loss is recognised for the amount by which the asset’s carrying 
amount exceeds its recoverable amount. The recoverable amount is the higher of an asset’s fair value less costs to 
sell and value in use. For the purposes of assessing impairment, assets are  reviewed at the lowest levels for which 
there are separately identifiable cash flows (cash-generating units).  

Non-financial assets other than goodwill that suffered impairment are reviewed for possible reversal of the impairment 
at each reporting date. 

Provisions  

A  provision  is  recognised in  the statement of  financial  position  when  the  Group has  a  present  legal or constructive 
obligation as a result of a past event, and it is probable that an outflow of economic benefits will be required to settle 
the obligation. If the effect is material, provisions are determined by discounting the expected future cash flows  at a 
pre-tax  rate  that  reflects  current  market  assessments  of  the  time  value  of  money  and,  when  appropriate,  the  risks 
specific to the liability. The increase in the provision due to the passage of time is recognised in finance costs.  

Polarean Imaging plc 
42 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

3 

Significant accounting policies continued 

Financial assets  

The  Group  classifies  all  of  its  financial  assets  at  amortised  cost.    Financial  assets  do  not  comprise  prepayments. 
Management determines the classification of its financial assets at initial recognition. 

Amortised costs 

The  Group's  financial  assets  held  at  amortised  cost  comprise  trade  and  other  receivables  and  cash  and  cash 
equivalents in the consolidated statement of financial position. 

These assets are non-derivative financial assets with fixed or determinable payments that are not quoted in an active 
market.  They arise principally through the provision of goods and services to customers (e.g. trade receivables), but 
also incorporate other types of contractual monetary asset.  They are initially recognised at fair value plus transaction 
costs that are directly attributable to their acquisition or issue and are subsequently carried at amortised cost using the 
effective interest rate method, less provision for impairment. 

Impairment provisions for trade receivables are recognised based on the simplified approach within IFRS 9 using the 
lifetime  expected  credit  losses.  During  this  process  the  probability  of  the  non-payment  of  the  trade  receivables  is 
assessed. This probability is then multiplied by the amount of the expected loss arising from default to determine the 
lifetime expected credit loss for the trade receivables. For trade receivables, which are reported net; such provisions 
are  recorded  in  a  separate  provision  account  with  the  loss  being  recognised  within  administrative  expenses  in  the 
consolidated statement of comprehensive income. On confirmation that the trade receivable will not be collectable, the 
gross carrying value of the asset is written off against the associated provision. 
These assets arise principally from the provision of goods and services to customers (e.g. trade receivables), but also 
incorporate other types of financial assets where the objective is to hold their assets in order to collect contractual cash 
flows and the contractual cash flows are solely payments of the principal and interest. They are initially recognised at 
fair value plus transaction costs that are directly attributable to their acquisition or issue and are subsequently carried 
at amortised cost using the effective interest rate method, less provision for impairment. 

Impairment provisions for other receivables are recognised based on the general impairment model within IFRS 9.  In 
doing so, the Company follows the 3-stage approach to expected credit losses.  Step 1 is to estimate the probability 
that the debtor will default over the next 12 months.  Step 2 considers if the credit risk has increased significantly since 
initial recognition of the debtor.  Finally, Step 3 considers if the debtor is credit impaired, following the criteria under IAS 
39. 

Financial liabilities 

The Group classifies its financial liabilities in the category of financial liabilities at amortised cost.  All financial liabilities 
are recognised in the statement of financial position when the Group becomes a party to the contractual provision of 
the instrument. 

Financial liabilities measured at amortised cost include: 

• 

Trade  payables  and  other  short-dated  monetary  liabilities,  which  are  initially  recognised  at  fair  value  and 
subsequently carried at amortised cost using the effective interest rate method. 

•  Bank and other borrowings are initially recognised at fair value net of any transaction costs directly attributable 
to the issue of the instrument.  Such interest-bearing liabilities are subsequently measured at amortised cost 
using the effective interest rate method, which ensures that any interest expense over the period to repayment 
is at a constant rate on the balance of the liability carried in the consolidated statement of financial position. 
For the purposes of each financial liability, interest expense includes initial transaction costs and any premium 
payable on redemption, as well as any interest or coupon payable while the liability is outstanding. 

Unless otherwise indicated, the carrying values of the Group’s financial liabilities measured at amortised cost represents 
a reasonable approximation of their fair values. 

Employee benefits: pension obligations  

The Group operates a defined contribution plan. A defined contribution plan is a pension plan under which the Group 
pays  fixed  contributions  into  a  separate  entity.  The  Group  has  no  legal  or  constructive  obligations  to  pay  further 
contributions if the fund does not hold sufficient assets to pay all employees the benefits relating to employee service 
in the current and prior periods.  

The Group has no further payment obligations once the contributions have been paid. The contributions are recognised 
as employee benefit expense when they are due. Prepaid contributions are recognised as an asset to the extent that 
a cash refund or a reduction in the future payments is available. 

Polarean Imaging plc 
43 

 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

3 

  Significant accounting policies continued 

Net finance costs 

Finance costs 
Finance costs comprise interest payable on borrowings, direct issue costs, dividends on preference shares and foreign 
exchange losses; and are expensed in the period in which they are incurred. 

Finance income 
Finance income comprises interest receivable on funds invested, and foreign exchange gains.  

Interest income is recognised in the income statement as it accrues using the effective interest method. 

Leases 

Leases are classified as finance leases whenever the terms of the lease transfer substantially all the risks and rewards 
of ownership to the lessee. All other leases are classified as operating leases. 

Leases in which a significant portion of the risks and rewards of ownership are retained by the lessor are classified as 
operating leases. The costs associated with operating leases are taken to the income statement on an accruals basis 
over the period of the lease.  

Income tax  

Income  tax  for  the  years  presented  comprises  current  and  deferred  tax.  Income  tax  is  recognised  in  the  income 
statement except to the extent that it relates to items recognised directly in equity, in which case it is recognised in 
equity.  Current  tax  is  the  expected  tax  payable  on  the  taxable  income  for  the  year,  using  tax  rates  enacted  or 
substantively  enacted  at  the  statement  of  financial  position  date,  and  any  adjustment  to  tax  payable  in  respect  of 
previous years.  

Deferred tax is recognised on temporary differences arsing between the tax bases of assets and liabilities and their 
carrying amounts.  

The following temporary differences are not recognised if they arise from a) the initial recognition of goodwill, and b) for 
the initial recognition of other assets or liabilities in a transaction other than a business combination that at the time of 
the transaction affects neither accounting nor taxable profit or loss. Deferred tax is determined using tax rates and laws 
that have been enacted or substantially enacted by the balance sheet date and are expected to apply when the related 
deferred tax asset is realised or the deferred income tax liability is settled. 

A deferred tax asset is recognised only to the extent that it is probable that future taxable profits will be available against 
which the asset can be utilised. Deferred tax assets are reduced to the extent that it is no longer probable that the 
related tax benefit will be realised.  

Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets 
against current tax liabilities and when the deferred income taxes assets and liabilities relate to income taxes levied by 
the same taxation authority on either the taxable entity or different taxable entities where there is an intention to settle 
the balances on a net basis.  

Critical accounting estimates and judgements 

The preparation of the Group’s financial statements under IFRS as endorsed by the EU requires the directors to make 
estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent 
assets and liabilities. Estimates and judgements are continually evaluated and are based on historical experience and 
other factors including expectations of future events that are believed to be reasonable under the circumstances. Actual 
results may differ from these estimates.  

The directors consider that the following estimates and judgements are likely to have the most significant effect on the 
amounts recognised in the financial statements.  

Carrying value of intangible assets 
In  determining  whether  there  are  indicators  of  impairment  of  the  Group’s  intangible  assets,  the  directors  take  into 
consideration various factors including the economic viability and expected future financial performance of the asset 
and when it relates to the intangible assets arising on a business combination, the expected future performance of the 
business acquired.  

Polarean Imaging plc 
44 

 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
4 

Segmental Information 

 Notes to the Financial Statements 
continued 

IFRS 8 requires operating segments to be identified on the basis of internal reports about components of the  Group 
that are regularly reviewed by the chief operating decision maker (which takes the form of the Board of Directors) as 
defined in IFRS 8, in order to allocate resources to the segment and to assess its performance. 

The chief operating decision maker has determined that the Group has one operating segment, the development and 
commercialisation of gas polariser devices and ancillary instruments. Revenues are reviewed based on the products 
and services provided: Polarisers, Parts and Upgrades, Service and Other revenue. 

The Group operates in Canada, Germany, the United Kingdom and the United States of America. Revenue by origin 
of geographical segment for all entities in the Group is as follows: 

Revenue 

Canada 

Germany 

United Kingdom 

United States of America 

Total 

 Non-current assets 

United States of America 

Total 

Product and services revenue analysis 

 Revenue 

Polarisers 

Parts and Upgrades 

Service 

Grants 

Total 

2018 

US$ 

163,677 

15,117 

38,661 

2,221,684 

2,439,139 

2017 

US$ 

340,113 

24,617 

111,765 

760,668 

1,237,163 

2018 

US$ 

2017 

US$ 

4,074,689 

4,074,689 

4,695,130 

4,695,130 

2018 

US$ 

1,056,728 

56,610 

117,220 

1,208,581 

2,439,139 

2017 

US$ 

340,113 

91,529 

154,528 

650,993 

1,237,163 

Management measures revenues by reference to the Group’s core services and products and related services, which 
underpin such income. 

Polarean Imaging plc 
45 

 
 
 
 
 
 
 
 
  
 
 
 
 
 
  
  
 
 
 
 
 
 
 
  
  
 
 
 
 
 
 Notes to the Financial Statements 
continued 

5 

Employees and Directors 

Staff costs for the Group and the Company during the year: 

Wages and salaries 

Social security costs 

Average monthly number of people (including directors) employed by activity: 

Senior management including directors 

R&D and clinical trial 

Administration 

Total 

2018 

US$ 

1,667,233 

367,748 

2,034,981 

2018 

No. 

9 

7 

1 

17 

2017 

US$ 

837,619 

321,009 

1,158,628 

2017 

 No.  

5 

7 

1 

13 

Key management compensation: 
The following table details the aggregate compensation paid to key management personnel. 

Salaries and fees 

Social security costs 

2018 

US$ 

873,229 

331,771 

1,205,000 

2017 

US$ 

512,636 

196,462 

709,098 

Key  management  personnel  include  all  directors  who  together  have  authority  and  responsibility  for  planning, 
directing, and controlling the activities of the Group and senior divisional managers.  

6 

Operating loss 

Depreciation 

-  Owned plant and equipment 

- 

Leased plant and equipment 

Amortisation of intangible assets 

Research expenses 

Operating lease costs 

Auditors remuneration (note 8) 

7 

Net finance expense 

Interest income 

Total finance income 

Finance expense 

Total finance expense 

Polarean Imaging plc 
46 

2018 
US$ 

9,601 

539 

616,852 

672,633 

77,971 

42,938 

2018   
US$ 

184 

184 

188,055 

188,055 

2017 
US$ 

6,939 

539 

361,746 

167,655 

68,335 

143,792 

2017   
US$ 

129 

129 

34,056 

34,056 

 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
  
  
 
 
 
 
  
 
  
 
 
 
  
  
 
  
  
  
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

8 

Auditor remuneration  

Auditors remuneration 

Fees payable to the Group’s auditor for audit of Parent 
Company and Consolidated Financial Statements 

Fees payables to the Group’s auditor for other services 
(assurance related services) 

9 

Loss per share 

2018 
US$ 

2017 
US$ 

42,938 

45,237 

- 

98,555 

The loss per share has been calculated using the loss for the year and the weighted average number of ordinary 
shares outstanding during the year, as follows: 

Loss for the year attributable to shareholders of the Group 
(US$) 
Weighted average number of ordinary shares 

Basic and diluted loss per share  

2018   
US$ 

2017   
US$ 

(5,454,659) 
69,940,338 

(3,957,821) 
28,460,390 

(0.078) 

(0.139) 

For  diluted  loss  per  share,  the  weighted  average  number  of  ordinary  shares  in  issue  is  adjusted  to  assume 
conversion of all potential dilutive warrants, options and convertible loans over ordinary shares. Potential ordinary 
shares  resulting  from  the  exercise  of  warrants,  options  and  the  conversion  of  convertible  loans  have  an  anti-
dilutive effect due to the  Group being in a loss position. As a result, diluted loss per share is disclosed as the 
same value as basic loss per share. 

The Group sub-divided its share capital on the basis of 26.71999:1 in February 2018. The weighted average for 
the year ended 31 December 2017 reflects this. 

10 

Taxation 

There were no charges to current corporate taxation due to the losses incurred by the Group in the period. No deferred 
tax assets have been recognised due to the uncertainty of reversal being dependant on future taxable profits. 

Income taxes computed at the statutory federal income tax of 21% (2017: 35%) and the state income tax of 3.30% 
(2017: 3.30%). UK corporation tax is calculated at 19% of the estimated assessable profits for the year. 

Loss on ordinary activities before tax 
Loss on ordinary activities multiplied by the rate of corporation tax in 
the US as above 
Effects of: 

Adjustments for rate of tax in other jurisdictions 

Unrelieved tax losses carried forward 

Total taxation charge 

2018   
US$ 
(5,454,659) 

2017   
US$ 
(3,957,821) 

(1,145,478) 

(1,385,237) 

26,611 
1,118,867 

- 

226,518 
1,158,719 

- 

The tax reform act of 1986 contains provisions which limit the ability to utilise the net operating loss carryforwards in 
the  case  of  certain  events  including  significant  changes  in  ownership  interests.  If  the  Group’s  net  operating  loss 
carryforward, the Group would incur a federal income tax liability even though net operating loss carryforwards would 
be available in future years.

Polarean Imaging plc 
47 

 
 
 
 
 
  
  
 
 
 
  
  
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 11 

Property, plant and equipment 

 Notes to the Financial Statements 
continued 

Leasehold 
improvements 
US$ 

Furniture and 
equipment  
US$ 

Computers 
and IT 
equipment  
US$ 

Cost 
At 1 January 2017 

Additions 

At 31 December 2017 

Additions 

At 31 December 2018 

Accumulated depreciation 

At 1 January 2017 

Depreciation expense 

At 31 December 2017 

Depreciation expense 

At 31 December 2018 

Carrying amount 

At 31 December 2017 

At 31 December 2018 

12 

Intangible assets 

2,695 

- 

2,695 

- 

2,695 

360 

539 

899 

539 

1,438 

1,796 

1,257 

27,671 

- 

27,671  

4,952 

32,623 

19,516 

2,775 

22,291 

3,380 

25,671 

5,380 

6,952 

8,232 

16,834 

25,066 

1,599 

26,665 

6,737 

4,164 

10,901 

6,221 

17,122 

14,165 

9,543 

Total  
US$ 

38,598 

16,834 

55,432 

6,551 

61,983 

26,613 

7,478 

34,091 

10,140 

44,231 

21,341 

17,752 

Cost 

At 1 January 2017 

Additions – m2m (see note 3 – basis of consolidation) 

At 31 December 2017 

Additions  

At 31 December 2018 

Accumulated amortisation 

 At 1 January 2017 

Amortisation expense 

At 31 December 2017 

Amortisation expense  

At 31 December 2018 

Carrying amount 

At 31 December 2017 

At 31 December 2018 

Patents 
US$ 

Total 
US$  

46,000 

46,000 

4,999,996 

4,999,996 

5,045,996 

5,045,996 

- 

- 

5,045,996 

5,045,996 

23,000 

361,746 

384,746 

616,852 

23,000 

361,746 

384,746 

616,852 

1,001,598 

1,001,598 

4,661,250 

4,044,398 

4,661,250 

4,044,398 

Polarean Imaging plc 
48 

 
  
 
  
  
  
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
13 

Investment in subsidiary undertakings 

 Notes to the Financial Statements 
continued 

Company 
Cost 
At 31 December 2017 
Additions 
At 31 December 2018 
Carrying amount 
At 31 December 2017 
At 31 December 2018 

Subsidiary Undertakings 
US$  

4,342,848 
- 
4,342,848 

4,342,848 
4,342,848 

The  Directors  annually  assess  the  carrying  value  of  the  investment  in  the  Subsidiary  and  in  their  opinion  no 
impairment provision is currently necessary.  

The  net  carrying  amounts  noted  above  relates  to  the  Subsidiary.  The  subsidiary  undertakings  during  the  year 
were as follows: 

Polarean Inc. 

Registered office address 
2500 Meridian Parkway #175, Durham, NC 27713, USA 

Country of 
incorporation 
USA 

Interest 
held 
% 
100 

2017   
US$ 
- 

2017   
US$ 

- 

- 

- 

14 

Trade and other receivables 

Amounts falling due after one year 

Rental deposit 

                 Group 

                 Company 

2018   
US$ 
12,539 

2017   
US$ 
12,539 

2018   
US$ 
- 

Amounts falling due within one year 

Trade receivables 

Other receivables 

Prepayments 

Due from Group undertakings 

Called up share capital not fully paid 

Due from borrowings 

Group 

2018   
US$ 

166,277 

3,972,321 

87,367 

- 

620 

- 

4,226,585 

2017   
US$ 

750 

    Company 
2018   
US$ 

- 

415,331 

3,708,681 

31,686 

- 

620 

40,474 

488,861 

- 

5,661,930 

1,851,021 

- 

- 

- 

40,474 

9,370,611 

1,891,495 

The  Company’s  other  receivable  of  US$3.7  million  relates  to  the  funds  outstanding  from  the  share  issue  on  28 
December 2018. 

Analysis of trade receivables based on age of invoices  

2018 

2017 

< 30 
£’000 

31 – 60 
£’000 

61 -90 
£’000 

> 90  
£’000 

Total Gross 
£’000 

163,677 

2,600 

750 

- 

- 

- 

- 

- 

166,277 

750 

ECL 
£’000 

- 

- 

Total Net 
£’000 

166,277 

750 

The Group applies the IFRS 9 simplified approach to measuring expected credit losses (ECL) which uses a lifetime 
expected  loss  allowance  for  all  trade  receivables.  The  ECL  balance  has been determined  based  on historical data 
available to management in addition to forward looking information utilising management knowledge. Based on the 
analyses performed there is no material impact on the transition to ECL. The Company applies a similar approach to 
measuring ECL for the amounts due from group undertakings. 

Polarean Imaging plc 
49 

 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
14 

Trade and other receivables continued 

 Notes to the Financial Statements 
continued 

Trade receivables are amounts due from customers for goods sold or services performed in the ordinary course of 
business. They are generally due for settlement within 30 days and therefore are all classified as current. The majority 
of trade and other receivables are non-interest bearing. Where the effect is material, trade and other receivables are 
discounted using discount rates which reflect the relevant costs of financing. The carrying amount of trade and other 
receivables approximates fair value. 

15 

Inventory 

Component parts 

16 

Cash and cash equivalents 

            Group 

2018   
US$ 

2017   
US$ 

651,781 

649,860 

Cash at bank and in hand 

875,601 

960,217 

235,766 

Group 

2018   
US$ 

2017   
US$ 

Company 
2018   
US$ 

17 

Share capital 

The issued share capital of the Company was as follows: 

Allotted and called up - Ordinary shares 
of 0.037p each 

2018 
No. 

2018 
US$ 

At beginning of period 

Issue of shares on group reorganisation 

Issue of shares to investors 

Issue of shares upon converting loans 

At end of year 

48,470,142 

23,291 

- 

- 

42,286,709 

47,321,448 

23,540 

6,180,761 

4,939,303 

100,730,893 

2,596 

49,427 

- 

48,470,142 

2017 
No. 

2,672 

The Company was incorporated on 24 October 2016 with issued share capital of £1 comprising 1 ordinary share 
of £1 each.  On 30 May 2017 the share capital of the Group was divided into 100 ordinary shares of 1p each.  

On 30 May 2017 the Company issued 1,582,587 new ordinary shares as consideration for the acquisition of 100% 
of the issued share capital of the Subsidiary. 

On  31  May  2017,  the  Company  raised  US$2  million  of  pre-IPO  funding  by  way  of  the  issue  of  231,316  new 
ordinary shares at a price of £6.68 per share. 

On  16  February  2018  the  Company  sub-divided  its  share  capital  on  the  basis  of  26.71999:1.    The  number  of 
ordinary shares in issue in the Company at 31 December 2017 reflects the sub -division.  

On 28 March 2018 the Company issued 20,000,000 new ordinary shares at a price of £0.15 each. 

On 16 July 2018 the Company issued 5,000,000 new ordinary shares at a price of £0.16 each.  

On 28 December 2018,  the Company  issued 22,321,448  new  ordinary shares at  a price of  £0.14 each.  Of the 
US$4.0 million (excluding expenses) raised from investors, US$3.7 million remain outstanding at year-end. 

Polarean Imaging plc 
50 

2017   
US$ 

23,106 

2017 
US$ 

1 

20,320 

2,970 

- 

23,291 

 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
18 

Reserves  

 Notes to the Financial Statements 
continued 

Share premium 
Share  premium  represents  the  excess  of  subscription  amounts  for  the  issue  of  shares  over  nominal  value  of 
shares issued, less any attributable share issue costs. 

Group re-organisation reserve 
The group re-organisation reserve arose on the transaction under which the  Group acquired the Subsidiary by 
way of a group re-organisation. 

Other equity 
Includes the value of conversion rights on convertible loans. 

Share based payment reserve 
Cumulative fair value of options charged to the consolidated income statement net of transfers to the profit or loss 
reserve on exercised and cancelled/lapsed options.   

Accumulated losses 
Includes all current and prior year retained profits and losses. 

Merger reserve 
The balance on the merger reserve represents the fair value of the consideration given in excess of the nominal 
value of the ordinary shares issued in an acquisition made by the issue of shares where the transaction 
qualifies for merger relief under the Companies Act 2006. 

19 

Share-based payments 

Share options 
The  Company  grants  share  options  at  its  discretion  to  Directors,  management  and  employees.  These  are 
accounted for as equity settled transactions. Should the options remain unexercised after a period of ten years 
from  the  date  of  grant  the  options  will  expire  unless  an  extension  is  agreed  to  by  the  board.  Options  are 
exercisable at a price equal to the Company’s quoted market price on the date of grant or an exercise price to 
be determined by the board. 

Details of share options granted, exercised, lapsed and outstanding at the year -end are as follows: 

Outstanding at beginning of year 
Granted during the year 
Forfeited/lapsed during the year 
Outstanding at end of the year 

Exercisable at end of the year 

Number of 
share 
options 
2018 
 5,156,960  
 10,403,600  
 -  
 15,560,560  

 6,590,282  

Weighted 
average 
exercise 
price (US$) 
2018 
 0.02  
 0.20  

 -    

 0.13  

Number  
of share  
options 
2017 
 5,156,960  
 -  
 -  
 5,156,960  

 0.07  

 4,304,619  

Weighted 
average 
exercise 
price (US$) 
2017 
 0.02  

 -    
 -    

 0.02  

 0.01  

During the year ended 31 December 2018, 10,403,600 options were granted (2017: Nil). The options will vest in equal 
portions on an annual basis on the anniversary of Admission, over the four year period from the date of Admission. The 
options outstanding as at 31 December 2018 have an exercise price in the range of  US$0.0041 to US$0.20 (2017: 
US$0.0041 to US$0.0337).  

The fair value of options granted has been calculated using the Black Scholes model which has given rise to fair 
values per share of US$0.09. This is based on risk-free rates of 1.41% and volatility of 40.84%.  

The Black Scholes calculations for the options resulted in a charge of US$ 211,015 (2017: US$66,859) which has 
been expensed in the year. 

The weighted average remaining contractual life of the share options is 7.91 years (2017: 6.2 years).  

All share options are equity settled on exercise. 

On 23 May 2019, the Company granted 1.2 million share options to Chuck Osborne with an exercise price of 15 pence 
per share. 25% of the options shall vest on 29 April 2020 with the remaining 75% vesting in equal portions on the last 
day of each calendar month over the period of 36 months, starting on 31 May 2020. 

Polarean Imaging plc 
51 

 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

19 

Share based payments continued 

Share warrants 
The  Company  grants  share  warrants  at  its  discretion  to  Directors,  management,  employees,  advisors  and 
lenders.  These  are  accounted  for  as  equity  settled  transactions.  Terms  of  warrants  very  from  agreement  to 
agreement. 

Details for the warrants granted, exercised, lapsed and outstanding at the year-end are as follows: 

Number of 
share warrants 
2018 
 9,065,428  

Weighted 
average exercise 
price (US$) 
2018 
 0.15  

Number of 
share warrants  
2017 
 5,081,449  

Weighted 
average 
exercise price 
(US$) 
2017 
 0.01  

 866,236  

 0.20  

 3,983,979  

 0.33  

(2,908,125)  

 0.30  

 -  

 -    

7,023,539  

 0.09  

 9,065,428  

 0.15  

 7,023,539  

 0.09  

 4,371,841  

 0.00  

Outstanding at beginning of year 

Granted during the year 

Forfeited/lapsed during the year 

Outstanding at end of the year 

Exercisable at end of the year 

On 30 May 2017, by way of a Warrant Substitution Agreement the  outstanding warrants in the Subsidiary were 
substituted into warrants over shares in the Company. The Warrant Substitution Agreement did not vary or amend 
any of the terms and conditions of the warrants granted. 

On  completion  of  the  m2m  merger  the  Company  granted  a  warrant  of  5%  of  the  issued  share  capital  of  the 
Subsidiary  following  the  merger  to  Amphion  Innovations  Plc,  Robert  Bertoldi  and  Richard  Morgan.  A  total  of 
2,618,373 warrants were issued pursuant to the Amphion Warrant Instrument. 

On 31 May 2017 the Company granted 1,236,174 warrants to subscribers as part of the pre -merger fundraise on 
31  May  2017  (Subscriber Warrants).  These  warrants  can  be  exercised  at  any  time  from  Admission  to  25  May 
2021. 

As part of the pre-Admission fundraising which was completed in December 2017 the Company granted 129,432 
warrants to subscribers (Pre-Admission Fundraise Warrants). These warrants can be exercised at any time from 
Admission to 25 May 2021. 

On 11 January 2018 the Company granted 866,236 warrants to subscribers with an exercise price of 15 pence 
per share which vested immediately and expiry on 31 March 2019. 

On 16 February 2018 the Company sub-divided its share capital on the basis of 26.71999:1. The warrants 
above reflect this event. 

The fair value of options granted during the year have been calculated using the Black Scholes model which has 
given rise to fair values per share of US$0.04. This is based on risk-free rates of 1.41% and volatility of 40.84%. 

Polarean Imaging plc 
52 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
19 

Share based payments continued 

 Notes to the Financial Statements 
continued 

The Black Scholes calculations for warrants resulted in a charge of US$40,775 (2017: US$348,007) which has 
been expensed in the year.  

The weighted average remaining contractual life of the share warrants is  4.1 years (2017: 3.6 years). 

On 2 April 2019 the Company issued 705,040 new ordinary shares of £0.00037 each in the capital of the Company 
at  the  exercise  price  of  15  pence  per  share,  following  the  exercise  of  warrants  from  certain  investors  that 
subscribed in January 2018. The total consideration received by the Company pursuant to the warrant exercise 
will be £105,756. The remaining 157,796 warrants issued in January 2018 lapsed on 1 April 2019. 

20 

Provision for contingent consideration 

Provision for contingent consideration 

Group 

Company 

2018   
US$ 
316,000 

2017   
US$ 
316,000 

2018   
US$ 
- 

2017   
US$ 
- 

On 19 December 2011, the Subsidiary entered into an agreement with a third party to purchase various assets, 
including patents, trademarks, a license agreement and physical inventory. As consideration for this transaction, 
the Subsidiary agreed to pay 5 per cent. of gross revenue on clinical sales of products that are sold related to the 
patents purchased, for seven years from the date of the commercial sale. As of 31 December 2018, the fair value 
of  this  contingent  consideration  was  US$316,000  (2017:  US$316,000).  This  liability  is  valued  based  on  a 
probability weighted expected return method using projected future cash flows.  There were no significant events 
in  the  year  ended  31  December  2018  necessitating  revision  of  the  probability  weighted  expected  value  of  the 
contingent consideration. 

There was therefore no profit or loss arising on revaluation of contingent consideration during the year ended 31 
December 2018 (2017: nil). 

21 

Deferred income 

Arising from service contracts 

Current 

Non-current 

22 

Trade and other payables 

Trade payables 

Accruals and other payables 

Royalties 

Group 

2018   
US$ 

54,829 

70,726 

125,555 

2017   
US$ 

26,562 

- 

26,562 

Company 

2018   
US$ 

- 

- 

- 

Group 

Company 

2018   
US$ 
417,356 

923,126 

250,000 

2017   
US$ 
711,363 

945,013 

250,000 

1,590,482 

1,906,376 

2018   
US$ 
- 

28,174 

- 

28,174 

2017   
US$ 

- 

- 

- 

2017   
US$ 
- 

25,742 

- 

25,742 

Trade payables and accruals principally comprise amounts outstanding for trade purchases and ongoing costs 
and are payable within 1 year.  

Royalties comprise a fixed payment of US$250,000 in relation to an agreement entered into by the  Subsidiary 
for the use of patents, see note 24 – Royalty commitments. 

The Directors consider the carrying value of all financial liabilities to be equivalent to their fair value.  

Polarean Imaging plc 
53 

 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
  
  
 
 
 
 
23 

Borrowings and loans 

 Notes to the Financial Statements 
continued 

Related party loans 

Overdraft 

Note payable 

Convertible loan notes 

Group 

Company 

2018   
US$ 
- 

5,213 

- 

- 

2017   
US$ 
47,086 

- 

265,750 

791,887 

5,213 

1,104,723 

2018   
US$ 
- 

- 

- 

- 

- 

2017   
US$ 
- 

- 

- 

785,747 

785,747 

In June 2013, an unsecured subordinated promissory note was issued to a related party for a principal amount 
of  US$8,000  per  month  for  18  months  for  a  total  of  US$144,000.  The  note  bears  interest  at  3  per  cent.  per 
annum. All principal and outstanding interest on the note is was repaid in December 2018. 

In April 2017, an unsecured loan note was issued for a principal amount of US250,000. The note bears interest 
at 6.75 per cent. per annum. All principal and outstanding interest on the note was repaid in April 2018.   

An  unsecured  promissory  note  that  was  issued  in  June  2017  for  a  principal  amount  of  US$150,000,  with  an 
interest rate of 6 per cent per annum, was settled in full including all outstanding interest in April 2018.   

In  December  2017,  an  unsecured  convertible  loan  note  was  issued  for  a  principal   amount  of  US$903,000 
(£647,147) was converted with accrued interest, into 4,939,303 ordinary shares in the Company at a conversion 
price equal to 90 per cent of the issue price of the ordinary shares upon admission.  

Net debt reconciliation 

Cash and cash equivalents 

Current borrowings 
Net debt 

2018 
US$ 

2017 
US$ 

875,601 

(5,213) 

      960,217 
    (1,104,723)  

870,388 

       (144,506)  

Cash and cash 
equivalents 
US$ 

Current 
borrowings 
US$ 

Total 
US$ 

Net debt at 1 January 2017 

        97,847  

       (104,541) 

        (6,694)  

Cash flows 
Other non-cash movements 

      862,370  

     (1,047,014) 

               -                    46,832    

    (184,644) 
       46,832 

Net debt at 31 December 2017 

      960,217  

     (1,104,723) 

    (144,506) 

Cash flows 
Other non-cash movements 

(84,616) 
- 

307,623 
791,887 

223,007 
791,887 

Net debt at 31 December 2018 

875,601 

(5,213) 

870,388 

Polarean Imaging plc 
54 

 
 
 
  
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
     
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

24 

Commitments 

Royalty commitments 

The  Subsidiary  has  entered  into  three  agreements  requiring  royalty  payments.  One  agreement  is  conditional  and 
requires a payment of 5 per cent. of gross revenue on clinical sales during the payment period beginning on the date 
a product is first commercially sold, contingent on receiving FDA approval, and ending seven years from that date. A 
separate agreement requires payments of 0.25 per cent of net sales of machines, and 20 per cent of any sublicensing 
income for a specific method of use of patent beginning in 2016. Additionally, beginning five years after the effective 
date of 1 February 2021, there are minimum yearly royalties of US$5,000. The third agreement requires a fixed payment 
of US$250,000 for use of patents. 

Operating lease commitments 

At  31  December  2018,  the  Company  was  committed  to  making  the  following  payments  under  non-cancellable 
operating leases: 

No later than one year 

Later than one year, and not later than five years 

Total 

                          Land & Buildings 
2018 
US$ 

2017 
US$ 

73,522 

109,899 

183,421 

72,205 

183,421 

255,626 

The  operating  lease  commitments  for  the  rental  of  the  property  is  calculated  on  a  straight -line  basis  over  the 
length of the lease.  

25 

Financial instruments 

The Group has exposure to the following key risks related to financial instruments:  

i. 
ii. 
iii. 

Market risk 
Credit risk 
Liquidity risk 

This note presents information about the Group’s exposure to each of the above risks, the Group’s objectives, 
policies  and  processes  for  measuring  and  managing  risk,  and  the  Group’s  management  of  capital.  Further 
quantitative disclosures are included throughout these consolidated Financial Statements.  

The Group uses financial instruments including cash, loans, as well as trade receivables and payables that arise 
directly from operations. 

Due to the simple nature of these financial instruments, there is no material difference between book and fair 
values, discounting would not give a material difference to the results of the Group and the Directors believe 
that there are no material sensitivities that require additional disclosure. 

(a) 

Credit risk 

Credit risk refers to the risk that a counterparty will default on its contractual obligations resulting in financial loss to 
the  Subsidiary.  In  order  to  minimise  the  risk,  the  Subsidiary  endeavours  only  to  deal  with  companies  which  are 
demonstrably creditworthy and this, together with the aggregate financial exposure, is continuously monitored. The 
maximum exposure to credit risk is the value of the outstanding amount. 

The Directors do not consider that there is any concentration of risk within either trade or other receivables. There are 
no impairments to trade or other receivables in each of the years presented. 

The Company has made unsecured interest-free loan to its Subsidiary and is repayable on demand and is expected 
to be repaid in the future as the Subsidiary is revenue generative. 

Polarean Imaging plc 
55 

 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

Financial instruments continued 

25 

Categories of financial instruments 

Cash and cash equivalents 

Loans and receivables 

Group 

Company 

2018   
US$ 
875,601 

2017   
US$ 
960,217 

2018   
US$ 
235,766 

2017   
US$ 
23,106 

Trade and other receivables – current 

4,226,585 

488,861 

9,370,611 

1,891,495 

12,539 

12,539 

- 

- 

Trade and other receivables – non-current 
Financial Liabilities measured at 
amortised cost 
Trade and other payables 

1,590,482 

1,906,376 

28,174 

Borrowings – current 

5,213 

1,104,723 

- 

Borrowings 

Financial Instruments 
Related Party Loans 

Overdraft 

Note payable 

Convertible Loan Notes 

Total 

Group 

Company 

2018   
US$ 
- 

5,213 

- 

- 

2017   
US$ 
47,086 

- 

265,750 

791,887 

5,213 

1,104,723 

2018   
US$ 
- 

- 

- 

- 

- 

25,742 

785,747 

2017   
US$ 
- 

- 

- 

785,747 

785,747 

In June 2013, an unsecured subordinated promissory note was issued to Technology  Commercialization Group, for 
whom Kenneth West was a retained consultant, for a principal amount of US$8,000 per month for 18 months for a total 
of US$144,000. The note bears interest at 3 per cent. per annum. This was repaid in full in December 2018. 

In December 2017, an unsecured convertible loan note was issued for a principal amount of US$903,000 (£647,147) 
was converted with accrued interest, into 4,939,303 ordinary shares in the Company at a conversion price equal to 90 
per cent of the issue price of the ordinary shares upon admission.   

Capital risk management 

The Group manages its capital to ensure that it will be able to continue as a going concern while maximising returns to 
shareholders through the optimisation of debt and equity balances. The Group is both equity and debt funded, and 
these two elements combine to make up the capital structure of the business. Equity comprises share capital, share 
premium and retained losses and is equal to the amount shown as ‘Equity’ in the statement of financial position. Debt 
comprises various items which are set out in further detail above and in note 23.  

The Group manages the capital structure and makes adjustments to it in the light of changes to economic conditions 
and risks.  

Polarean Imaging plc 
56 

 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notes to the Financial Statements 
continued 

25 

Financial instruments continued 

(b) 

Market risk 

The interest rate profile of the Subsidiary’s borrowings is shown below: 

Interest rate profile of interest-bearing borrowings: 

Fixed rate borrowings 
Related party loans 

Weighted average cost of fixed rate 
borrowings 

2018 

Debt 
US$ 

Interest rate 

- 

- 

-% 

-% 

2017 

Debt 
US$ 

Interest rate 

24,852 

6-10% 

24,852 

8% 

Details of the above borrowings can be found in note 23 above. 

Interest rate sensitivity analysis 

As the interest rates on shareholders loans are fixed, interest rate risk is considered to be very low. 

(c) 

Liquidity risk 

A maturity analysis of the Group’s borrowings is shown below: 

Less than one year 
One to two years 
Two to five years 
Total including interest cash flows 
Less: interest cash flows 
Total principal cash flows 

Derivatives 

The Group and Company have no derivative financial instruments. 

26 

Contingent liabilities 

2018 
US$ 
5,213 
- 
- 
5,213 
- 
5,213 

2017 
US$ 
49,631 
- 
- 
49,631 
(2,545) 
47,086 

The Directors are not aware of any material contingent liabilities, except for the contingent consideration detailed in 
note 20.  

27 

Related party transactions 

In June 2013, an unsecured subordinated promissory note was issued to Technology Commercialization Group, for 
whom Ken West was a retained consultant, for a principal amount of US$8,000 per month for 18 months for a total of 
US$144,000. The note bears interest at 3 per cent per annum. All principal and outstanding interest on the note was 
due 3 June 2016. This was repaid in full in December 2018. 

28 

Events after the reporting period 

On the 2 April 2019, the Company issued 705,040 new ordinary shares of £0.00037 each at an exercise price of 15 
pence per share in relation to the warrants exercised by certain investors that subscribed for Convertible Loan Notes 
the Group undertook in a pre-Admission fundraise in December 2017. The Company received £105,756.  

On 23 May 2019, the Company granted 1.2 million share options to Chuck Osborne with an exercise price of 15 pence 
per share. 25% of the options shall vest on 29 April 2020 with the remaining 75% shall vest  in equal portions on the 
last day of each calendar month over the period of 36 months, starting on 31 May 2020. 

Polarean Imaging plc 
57 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notice of the Annual General Meeting 

POLAREAN IMAGING PLC 
(Incorporated in England and Wales under the Companies Act 2006 with company 
number 10442853) 

NOTICE OF ANNUAL GENERAL MEETING 

THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION 

If you are in any doubt as to what action you should take, you are recommended to seek your 
own financial advice from your stockbroker or other independent adviser authorised under 
the Financial Services and Markets Act 2000. 

If you have recently sold or transferred all of your shares in Polarean Imaging plc, please 
forward  this  document,  together  with  the  accompanying  documents,  as  soon  as  possible 
either to the purchaser or transferee or to the person who arranged the sale or transfer so 
they can pass these documents to the person who now holds the shares. 

NOTICE IS HEREBY GIVEN that the second annual general meeting of Polarean Imaging plc (the 
'Company') will be held at the offices of Reed Smith LLP at The Broadgate Tower, 20 Primrose 
Street,  London  EC2A  2RS  at  2.00  p.m.  on  25  July  2019  for  the  purpose  of  considering  and,  if 
thought fit, transacting the following business: 

ORDINARY BUSINESS 

To consider and, if thought fit, pass the following resolutions which will be proposed as ordinary resolutions: 

1.  To receive and consider the Company's audited accounts for the year ended 31 December 2018 and the directors' 

of the Company (“Director(s)”) and auditors' reports thereon.  

2.  To consider and approve the remuneration report as detailed in the Company’s annual report and accounts.  

3.  To re-appoint Crowe UK LLP as auditor of the Company (the “Auditors”) to hold office until the conclusion of the next 

general meeting at which accounts are laid and to authorise the Directors to fix the auditor’s remuneration.  

4.  To re-elect Richard Hullihen as a Director, who retires in accordance with article 78 of the Articles, and who, being 

eligible, offers himself for re-election. 

5.  To re-elect Bastiaan Driehuys as a Director, who retires in accordance with article 78 of the Articles, and who, being 

eligible, offers himself for re-election. 

6.  To re-elect Robert Bertoldi as a Director, who retires in accordance with article 78 of the Articles, and who, being 

eligible, offers himself for re-election. 

7.  To generally and unconditionally authorise the Directors for the purpose of section 551 of the Companies Act 2006 
(the ‘Act’), in substitution for all existing authorities to the extent unused, to exercise all the powers of the Company 
to allot or grant rights to subscribe for or to convert any security into shares in the Company up to an aggregate 
number of 15,215,390 ordinary shares of £0.00037 each (“Ordinary Shares”) (being 15 per cent. of the total number 
of Ordinary Shares in issue as at the date of this notice) provided that this authority shall expire on the earlier 
of 15 months after the date of passing of this resolution and the conclusion of the annual general meeting 
of the Company next following the passing of this resolution, save that the Company may, before such 
expiry, make an offer or agreement which would or might require shares or equity securities, as the case 
may be, to be allotted or such rights granted after such expiry and the Directors may allot shares or equity 
securities  or  grant  such  rights,  as  the  case  may  be,  in  pursuance  of  such  offer  or  agreement 
notwithstanding that the authority conferred by this resolution has expired. 

Polarean Imaging plc 
58 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notice of the Annual General Meeting 

SPECIAL BUSINESS 

To consider and, if thought fit, pass the following resolutions as a special resolution:  

8.  Subject to the passing of resolution 7 above, to empower the Directors, pursuant to the general authority 
conferred on them and section 570 of the Act, to allot equity securities (within the meaning of section 560 of 
the Act) for cash as if section 561 of the Act did not apply to any such allotment, provided that this power 
shall be limited to the allotment of equity securities: 

8.1.  made in connection with an offer of securities, open for acceptance for a fixed period, to holders of 
Ordinary Shares of the Company on the register on a fixed record date in proportion (as nearly as may 
be)  to  their  then  holdings  of  such  Ordinary  Shares  (but  subject  to  such  exclusions  or  other 
arrangements as the Directors may deem necessary or expedient to deal with any  legal or practical 
problems under the laws or requirements of any recognised regulatory body or any stock exchange in 
any overseas territory or in connection with fractional entitlements); and/or 

8.2.  wholly  for  cash  (otherwise  than  pursuant  to  paragraph  8.1  above)  up  to  an  aggregate  number  of 

15,215,390 Ordinary Shares. 

This authority shall expire on the earlier of 15 months after the date of passing of this resolution and the 
conclusion of the annual general meeting of the Company next following the passing of this resolution but 
the Company may, before such expiry, make an offer or agreement which would or might require shares or 
equity securities, as the case may be, to be allotted or such rights granted after such expiry and the Directors 
may allot shares or equity securities or grant such rights, as the case may be, in pursuance of such an offer 
or agreement notwithstanding that the power conferred by this resolution has expired. 

By Order of the Board 

Stephen Austin 
Secretary 

26 June 2019 

Registered Office: 

27-28 Eastcastle Street 
London 
W1W 8DH 

Polarean Imaging plc 
59 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Notice of the Annual General Meeting 

NOTES 

(1) 

(2) 

(3) 

(4) 

(5) 

(6) 

(7) 

(8) 

(9) 

(10) 

(11) 

A shareholder entitled to attend and vote at the meeting convened by this notice is entitled to appoint one or more 
proxies to exercise all or any of their rights to attend, speak and vote on their behalf at the annual general meeting. A 
proxy need not be a shareholder. 

To appoint a proxy, shareholders should use the form of proxy enclosed with this notice of annual general meeting. 
Please carefully read the instructions on how to complete the form of proxy. For a proxy to be effective, the instrument 
appointing a proxy together with the power of attorney  or  such  other  authority  (if  any)  under  which  it  is  signed  or  a 
notarially  certified  copy  of  the  same  must  be  deposited  by  2.00  p.m.  (BST)  on  23  July  2019  with  the  Company’s 
registrars, Share Registrars Limited of The Courtyard, 17 West Street, Farnham, Surrey, GU9 7DR, United Kingdom 
(the ‘Registrars’). The completion and return of a form of proxy does not preclude a shareholder from subsequently 
attending and voting at the annual general meeting in person if he or she so wishes. If a shareholder has appointed a 
proxy and attends the annual general meeting in person, such proxy appointment will automatically be terminated. 
Pursuant  to  Regulation  41  of  Uncertificated  Securities  Regulations  2001,  the  Company  specifies  that  only  those 
shareholders on the register of members at 2.00 p.m. (BST) on 23 July 2019 or, if the meeting is adjourned, 48 hours 
before the time of the adjourned meeting (excluding any part of a day that is not a business day), shall be entitled to 
attend  or  vote  at  the  annual  general  meeting  in  respect  of  the  number  of  ordinary  shares  of  £0.00037  each  (the 
‘Ordinary Shares’) registered in their name at that time. Changes to the register of members after that time shall be 
disregarded in determining the rights of any person to attend or vote at the annual general meeting. 

Any Shareholder may insert the full name of a proxy or the full names of two alternative proxies of the Shareholder’s 
choice in the space provided with or without deleting ‘the Chairman of the meeting.’ A proxy need not be a Shareholder, 
but must attend the meeting to represent the relevant Shareholder. The person whose name appears first on the Form 
of Proxy and has not been deleted will be entitled to act as proxy to the exclusion of those whose names follow. If this 
proxy form is signed and returned with no name inserted in the space provided for that purpose, the Chairman of the 
meeting  will be deemed to be the appointed  proxy. Where a Shareholder appoints as his/her proxy someone other 
than  the  Chairman, the relevant Shareholder  is responsible for  ensuring  that  the  proxy  attends  the meeting  and is 
aware of the Shareholder’s voting intentions. Any alteration, deletion or correction made in the Form of Proxy must be 
initialed by the signatory/ies. 

A shareholder may appoint more than one proxy provided that each proxy is appointed to exercise the rights attached 
to a different Ordinary Share or Ordinary Shares held by that shareholder. A shareholder may not appoint more than 
one  proxy  to  exercise  rights  attached  to  any  one  Ordinary  Share. If a shareholder wishes to appoint more than one 
proxy, they should contact the Registrars on 01252 821390, +44 1252 821390 from overseas. Lines are open from 9.00 
a.m. to 5.30 p.m. Monday to Friday, excluding public holidays. Alternatively, you may write to the Registrars at Share 
Registrars Limited, The Courtyard, 17 West Street, Farnham, Surrey, GU9 7DR, United Kingdom for additional proxy 
forms and for assistance. 

Any corporation which is a shareholder can appoint one or more corporate representatives who may exercise on its 
behalf all of its powers as a shareholder provided that they do not do so in relation to the same Ordinary Share. 

As  at  the  close  of  business  on  the  date  immediately  preceding  this  notice,  the  Company's  issued  share  capital 
comprised 101,435,933 Ordinary Shares. Each Ordinary Share carries the right to vote at the Annual General Meeting 
and, therefore, the total number of voting rights in the Company  as  at  close  of  business  on  the  date  immediately 
preceding this notice is 101,435,933. 

A shareholder’s instructions to the proxy must be indicated in the appropriate space provided. To abstain from voting 
on a resolution, select the relevant ‘Vote withheld’ box. A vote withheld is not a vote in law, which means that the vote 
will not be counted in the calculation of votes for or against the resolution. If no voting indication is given, your proxy 
will vote or abstain from voting at his or her decision. Your proxy will vote (or abstain from voting) as he or she thinks 
fit in relation to any other matter which is put before the meeting. 

This form of proxy must be signed by the appointor or his attorney duly authorised in writing. The power of attorney or 
other authority (if any) under which the form of proxy is signed, or a notarially certified copy of the power or authority, 
must be received by the Registrars with the form of proxy. If the appointor is a corporation, the form of proxy should be 
signed on its behalf by an attorney or duly authorised officer or executed as a deed or executed under common seal. 
In the case of joint holders, the signature of any one of them will suffice, but the names of all joint holders should be 
stated. 

CREST members who wish to appoint a proxy or proxies through the CREST Electronic Proxy Appointment Service 
may do so for the Annual General Meeting to be held at 2.00 p.m. (BST) on 23 July 2019 and any adjournment(s) thereof 
by following the procedures described in the CREST manual. All messages relating to the appointment of a proxy or an 
instruction to  a  previously-appointed  proxy,  which  are  to be  transmitted  through  CREST,  must  be  received  by  the 
Registrars (ID 7RA36) no later than 2.00 p.m. (BST) on 23 July 2019, or, if the annual general meeting is adjourned, 
48 hours before the time fixed for the adjourned meeting (excluding any part of a day that is not a business day). 

In order to revoke a proxy instruction you will need to inform the Company by sending a signed hard copy notice clearly 
stating  your  intention  to  revoke  your  proxy  appointment  to  the  Registrars.  In  the  case  of  a  shareholder  which  is  a 
company, the revocation notice must be executed in accordance with note 12 below. Any power of attorney or any 
other authority under which the revocation notice is signed (or a duly certified copy of such power or authority) must 
be included with the revocation notice and must be received by the Registrars not less than 48 hours (excluding any 
part of a day that is not  a business day)  before  the time  fixed for the holding of the annual general meeting  or any 
adjourned meeting (or in the case of a poll before the time appointed for taking the poll) at which the proxy is to attend, 
speak and to vote. If you attempt to revoke your proxy appointment but the revocation is received after the time specified 
then, subject to the paragraph directly below, your proxy appointment will remain valid. 

(12) 

A  corporation’s  form  of  proxy  must be  executed  under either  its common  seal,  if  any,  or  under the  hand  of  a  duly 
authorised officer or attorney, in each case as required under the laws of its relevant jurisdiction.  

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